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Conserved domains on  [gi|149039373|gb|EDL93593|]
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neural proliferation, differentiation and control, 1, isoform CRA_e [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NPDC1 super family cl06049
Neural proliferation differentiation control-1 protein (NPDC1); This family consists of ...
 1-86 3.39e-37

Neural proliferation differentiation control-1 protein (NPDC1); This family consists of several neural proliferation differentiation control-1 (NPDC1) proteins. NPDC1 plays a role in the control of neural cell proliferation and differentiation. It has been suggested that NPDC1 may be involved in the development of several secretion glands. This family also contains the C-terminal region of the C. elegans protein CAB-1 which is known to interact with AEX-3.


The actual alignment was detected with superfamily member pfam06809:

Pssm-ID: 284276  Cd Length: 352  Bit Score: 128.00  E-value: 3.39e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149039373    1 MATPVPPPSPRHLRLLRLLLSGLILGAALNGATARRPDAPTCPGSLDCALKRRAKCPPGAHACGPCLQSFQEDQRGVCVP 80
Cdd:pfam06809   1 MATPLPPPSPRHLRLLRLLLSGLILGAALNGAAAGHPDAAACPGSLDCALKRRAKCPPGAHACGPCLQPFQEDQQGFCVP 80


                  ....*.
gi 149039373   81 RKHQSS 86
Cdd:pfam06809  81 RKHLSS 86
 
Name Accession Description Interval E-value
NPDC1 pfam06809
Neural proliferation differentiation control-1 protein (NPDC1); This family consists of ...
 1-86 3.39e-37

Neural proliferation differentiation control-1 protein (NPDC1); This family consists of several neural proliferation differentiation control-1 (NPDC1) proteins. NPDC1 plays a role in the control of neural cell proliferation and differentiation. It has been suggested that NPDC1 may be involved in the development of several secretion glands. This family also contains the C-terminal region of the C. elegans protein CAB-1 which is known to interact with AEX-3.


Pssm-ID: 284276  Cd Length: 352  Bit Score: 128.00  E-value: 3.39e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149039373    1 MATPVPPPSPRHLRLLRLLLSGLILGAALNGATARRPDAPTCPGSLDCALKRRAKCPPGAHACGPCLQSFQEDQRGVCVP 80
Cdd:pfam06809   1 MATPLPPPSPRHLRLLRLLLSGLILGAALNGAAAGHPDAAACPGSLDCALKRRAKCPPGAHACGPCLQPFQEDQQGFCVP 80


                  ....*.
gi 149039373   81 RKHQSS 86
Cdd:pfam06809  81 RKHLSS 86
 
Name Accession Description Interval E-value
NPDC1 pfam06809
Neural proliferation differentiation control-1 protein (NPDC1); This family consists of ...
 1-86 3.39e-37

Neural proliferation differentiation control-1 protein (NPDC1); This family consists of several neural proliferation differentiation control-1 (NPDC1) proteins. NPDC1 plays a role in the control of neural cell proliferation and differentiation. It has been suggested that NPDC1 may be involved in the development of several secretion glands. This family also contains the C-terminal region of the C. elegans protein CAB-1 which is known to interact with AEX-3.


Pssm-ID: 284276  Cd Length: 352  Bit Score: 128.00  E-value: 3.39e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149039373    1 MATPVPPPSPRHLRLLRLLLSGLILGAALNGATARRPDAPTCPGSLDCALKRRAKCPPGAHACGPCLQSFQEDQRGVCVP 80
Cdd:pfam06809   1 MATPLPPPSPRHLRLLRLLLSGLILGAALNGAAAGHPDAAACPGSLDCALKRRAKCPPGAHACGPCLQPFQEDQQGFCVP 80


                  ....*.
gi 149039373   81 RKHQSS 86
Cdd:pfam06809  81 RKHLSS 86
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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