NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|149045003|gb|EDL98089|]
View 

similar to Cyclin-dependent kinases regulatory subunit 2 (CKS-2) (predicted), isoform CRA_a [Rattus norvegicus]

Protein Classification

cyclin-dependent kinases regulatory subunit( domain architecture ID 10471449)

cyclin-dependent kinases regulatory subunit binds to the catalytic subunit of cyclin dependent kinases and is essential for their biological function

CATH:  3.30.170.10
Gene Ontology:  GO:0016538
PubMed:  25864384
SCOP:  4001729

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
CKS pfam01111
Cyclin-dependent kinase regulatory subunit;
1-51 2.64e-31

Cyclin-dependent kinase regulatory subunit;


:

Pssm-ID: 460068  Cd Length: 68  Bit Score: 103.01  E-value: 2.64e-31
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 149045003   1 MLPRELSKQVPKTHLMSEEEWRRLGVQQSLGWVHYMIHEPEPHILLFRRPL 51
Cdd:pfam01111 18 ILPKELAKKIPKNRLLTEEEWRNLGIQQSPGWEHYMIHKPEPHILLFRRPK 68
 
Name Accession Description Interval E-value
CKS pfam01111
Cyclin-dependent kinase regulatory subunit;
1-51 2.64e-31

Cyclin-dependent kinase regulatory subunit;


Pssm-ID: 460068  Cd Length: 68  Bit Score: 103.01  E-value: 2.64e-31
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 149045003   1 MLPRELSKQVPKTHLMSEEEWRRLGVQQSLGWVHYMIHEPEPHILLFRRPL 51
Cdd:pfam01111 18 ILPKELAKKIPKNRLLTEEEWRNLGIQQSPGWEHYMIHKPEPHILLFRRPK 68
CKS smart01084
Cyclin-dependent kinase regulatory subunit; Cyclin-dependent kinase regulatory subunit.
 1-52 8.80e-27

Cyclin-dependent kinase regulatory subunit; Cyclin-dependent kinase regulatory subunit.


Pssm-ID: 198152  Cd Length: 70  Bit Score: 91.63  E-value: 8.80e-27
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 149045003    1 MLPRELSKQVPKTHLMSEEEWRRLGVQQSLGWVHYMIHEPEPHILLFRRPLP 52
Cdd:smart01084 19 ILPKEIAKLVPKIRLLSENEWRKLGIQQSKGWEHYMIHKPEPHILLFRRPLN 70
PLN00010 PLN00010
cyclin-dependent kinases regulatory subunit; Provisional
 1-57 7.90e-23

cyclin-dependent kinases regulatory subunit; Provisional


Pssm-ID: 215027  Cd Length: 86  Bit Score: 82.29  E-value: 7.90e-23
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 149045003  1 MLPRELSKQVPKTHLMSEEEWRRLGVQQSLGWVHYMIHEPEPHILLFRRPLPKEQQK 57
Cdd:PLN00010 21 VLPPEVAKLLPKNRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQ 77
 
Name Accession Description Interval E-value
CKS pfam01111
Cyclin-dependent kinase regulatory subunit;
1-51 2.64e-31

Cyclin-dependent kinase regulatory subunit;


Pssm-ID: 460068  Cd Length: 68  Bit Score: 103.01  E-value: 2.64e-31
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 149045003   1 MLPRELSKQVPKTHLMSEEEWRRLGVQQSLGWVHYMIHEPEPHILLFRRPL 51
Cdd:pfam01111 18 ILPKELAKKIPKNRLLTEEEWRNLGIQQSPGWEHYMIHKPEPHILLFRRPK 68
CKS smart01084
Cyclin-dependent kinase regulatory subunit; Cyclin-dependent kinase regulatory subunit.
 1-52 8.80e-27

Cyclin-dependent kinase regulatory subunit; Cyclin-dependent kinase regulatory subunit.


Pssm-ID: 198152  Cd Length: 70  Bit Score: 91.63  E-value: 8.80e-27
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 149045003    1 MLPRELSKQVPKTHLMSEEEWRRLGVQQSLGWVHYMIHEPEPHILLFRRPLP 52
Cdd:smart01084 19 ILPKEIAKLVPKIRLLSENEWRKLGIQQSKGWEHYMIHKPEPHILLFRRPLN 70
PLN00010 PLN00010
cyclin-dependent kinases regulatory subunit; Provisional
 1-57 7.90e-23

cyclin-dependent kinases regulatory subunit; Provisional


Pssm-ID: 215027  Cd Length: 86  Bit Score: 82.29  E-value: 7.90e-23
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 149045003  1 MLPRELSKQVPKTHLMSEEEWRRLGVQQSLGWVHYMIHEPEPHILLFRRPLPKEQQK 57
Cdd:PLN00010 21 VLPPEVAKLLPKNRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQ 77
PTZ00453 PTZ00453
cyclin-dependent kinase; Provisional
 1-50 2.74e-22

cyclin-dependent kinase; Provisional


Pssm-ID: 185632  Cd Length: 96  Bit Score: 81.16  E-value: 2.74e-22
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|
gi 149045003  1 MLPRELSKQVPKTHLMSEEEWRRLGVQQSLGWVHYMIHEPEPHILLFRRP 50
Cdd:PTZ00453 45 ILPKDFARLVPRSRLMSESEWRQLGVQQSVGWRHYMIHKPEPHVLLFKRP 94
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH