|
Name |
Accession |
Description |
Interval |
E-value |
| Rabaptin |
pfam03528 |
Rabaptin; |
1-411 |
0e+00 |
|
Rabaptin;
Pssm-ID: 367545 [Multi-domain] Cd Length: 486 Bit Score: 650.24 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 1 MENIKAIATVSENTKQEAIDEVKRQWREEVASLQAVMKETVRDYEHQFHLRLEQERAQWAQYRESADREIADLRRRLSEG 80
Cdd:pfam03528 77 MENIKAVATVSENTKQEAIDEVKSQWQEEVASLQAIMKETVREYEVQFHRRLEQERAQWNQYRESAEREIADLRRRLSEG 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 81 QEEENLENEMKKAQEDAEKLRSVVMPMEKEIAALKDKLTEAEDKIKELEASKVKELNHYLEAEKSCRTDLEMYVAVLNTQ 160
Cdd:pfam03528 157 QEEENLEDEMKKAQEDAEKLRSVVMPMEKEIAALKAKLTEAEDKIKELEASKMKELNHYLEAEKSCRTDLEMYVAVLNTQ 236
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 161 KSVLQEDAEKLRKELHEVCHLLEQERQQHNQLKHTWQKANDQFLESQRLLMRDMQRMEIVLTSEQLRQVEELKKKDQEED 240
Cdd:pfam03528 237 KSVLQEDAEKLRKELHEVCHLLEQERQQHNQLKHTWQKANDQFLESQRLLMRDMQRMESVLTSEQLRQVEEIKKKDQEEH 316
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 241 EQQRINKGKDNKKIDTEEEVKIPVVCALTQEESSTPLSNEEEHLDSTHGSVHSLDADLLLPSGDPFSKSDnDMFKEGLRR 320
Cdd:pfam03528 317 KRARTHKEKETLKSDREHTVSIHAVFSPAGVETSAPLSNVEEQINSAHGSVHSLDTDVVLGAGDSFNKQE-DPFKEGLRR 395
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 321 AQSTDSLGTSSSLQSKALGYNYKAKSAGNLDESDFGPLVGADSVSENFDTVSLGSLQMPSGFMLTKDQERAIKAMTPEQE 400
Cdd:pfam03528 396 AQSTDSLGSSSSLQHKFLGHNQKAKSAGNLDESDFGPLVGADSVSENFDTSSLGSLKMPSGFMLTKDQEKAIKAMTPEQE 475
|
410
....*....|.
gi 149053242 401 ETASLLSSVTQ 411
Cdd:pfam03528 476 ETASLLSSVTQ 486
|
|
| Rab5-bind |
pfam09311 |
Rabaptin-like protein; Members of this family are predominantly found in Rabaptin and allow ... |
449-755 |
9.11e-123 |
|
Rabaptin-like protein; Members of this family are predominantly found in Rabaptin and allow for binding to the GTPase Rab5. This interaction is necessary and sufficient for Rab5-dependent recruitment of Rabaptin5 to early endosomal membranes.
Pssm-ID: 462752 [Multi-domain] Cd Length: 307 Bit Score: 370.45 E-value: 9.11e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 449 CDMCSNYEKQLQGIQIQEAETRDQVKKLQLMLRQANDQLEKTMKEKQELEDFLRQSAEDSSHQISALVLRAQASEVLLEE 528
Cdd:pfam09311 1 CDMCSNYEKQLQAIQEQEAETRDQVKKLQEMLRQANDQLEKTMKDKKELEDKMNQLSEETSNQVSTLAKRNQKSETLLDE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 529 LQQSFSQAKRDVQEQMAVLMQSREQVSEELVRLQKDNDSLQGKHSLHVSLQLAEDFILPDTVQVLRELVLKYRENIVHVR 608
Cdd:pfam09311 81 LQQAFSQAKRNFQDQLAVLMDSREQVSDELVRLQKDNESLQGKHSLHVSLQQAEKFDMPDTVQELQELVLKYREELIEVR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 609 TAADHMEEKLKAEILFLKEQIQAEQCLKENLEETLQLEIENCKEEIASISSLKAELERIKVEKGQLESTLREKSQQLESL 688
Cdd:pfam09311 161 TAADHMEEKLKAEILFLKEQIQAEQCLKENLEETLQAEIENCKEEIASISSLKVELERIKAEKEQLENGLTEKIRQLEDL 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 149053242 689 QEIKVNLEEQLKKETAAKATVEQLMFEEKNKAQRLQTELDVSEQVQRDFVKLSQTLQVQLERIRQAD 755
Cdd:pfam09311 241 QTTKGSLETQLKKETNEKAAVEQLVFEEKNKAQRLQTELDVSEQVQRDFVKLSQTLQVQLERIRQAD 307
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
50-758 |
3.70e-13 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 73.55 E-value: 3.70e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 50 LRLEQERAQWAQYRESADREIadlrrrlsegQEEENLENEMKKAQEDAEKLRSVVMPMEKEIAALKDKLTEAEDKIKELE 129
Cdd:TIGR02168 232 LRLEELREELEELQEELKEAE----------EELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLE 301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 130 ASKV-------------KELNHYLEAEKSCRTDLEMYVAVLNTQKSVLQEDAEKLRKELHEVCHLLEQERQQHNQLKHTW 196
Cdd:TIGR02168 302 QQKQilrerlanlerqlEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQL 381
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 197 QKAND---QFLESQRLLMRDMQRMEIVLTSEQLRQVEELKKKDQEEDEQQRINKGKDNKKIDTEEEVKIPVVCAL----T 269
Cdd:TIGR02168 382 ETLRSkvaQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELerleE 461
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 270 QEESSTPLSNE-EEHLDSTHGSVHSLDADL-----LLPSGDPFSKSDNDMFKEGLRRAQSTDSLGTSSSLQSK------- 336
Cdd:TIGR02168 462 ALEELREELEEaEQALDAAERELAQLQARLdslerLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGyeaaiea 541
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 337 ALGYNYKA----------KSAGNLDESDFGPLV--GADSVSENFDTVSLG-SLQMPSGFMLTKDqeRAIKAMTPEQEETA 403
Cdd:TIGR02168 542 ALGGRLQAvvvenlnaakKAIAFLKQNELGRVTflPLDSIKGTEIQGNDReILKNIEGFLGVAK--DLVKFDPKLRKALS 619
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 404 SLLS------SVTQGMESAYVSPSGYLLVSE------TEWNLLQKEVHNAGNKLGRRCDMcSNYEKQLQGIQIQEAETRD 471
Cdd:TIGR02168 620 YLLGgvlvvdDLDNALELAKKLRPGYRIVTLdgdlvrPGGVITGGSAKTNSSILERRREI-EELEEKIEELEEKIAELEK 698
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 472 QVKKLQLMLRQANDQLEKTMKEKQELEDFLRQSAEDsshqisalVLRAQASEVLLEELQQSFSQAKRDVQEQMAVLMQSR 551
Cdd:TIGR02168 699 ALAELRKELEELEEELEQLRKELEELSRQISALRKD--------LARLEAEVEQLEERIAQLSKELTELEAEIEELEERL 770
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 552 EQVSEELVRLQKDNDSLQgkhslhvslqlaedfilpDTVQVLRELVLKYRENIVHVRTAADHMEEKLkAEILFLKEQIQA 631
Cdd:TIGR02168 771 EEAEEELAEAEAEIEELE------------------AQIEQLKEELKALREALDELRAELTLLNEEA-ANLRERLESLER 831
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 632 EQCLKENLEETLQLEIENCKEEIAsisSLKAELERIKVEKGQLESTLREKSQQLESLQEIKVNLEEQLKKETAAKATVEQ 711
Cdd:TIGR02168 832 RIAATERRLEDLEEQIEELSEDIE---SLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELES 908
|
730 740 750 760
....*....|....*....|....*....|....*....|....*..
gi 149053242 712 LMFEEKNKAQRLQTELdvsEQVQRDFVKLSQTLQVQLERIRQADSLE 758
Cdd:TIGR02168 909 KRSELRRELEELREKL---AQLELRLEGLEVRIDNLQERLSEEYSLT 952
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
456-737 |
3.71e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 60.34 E-value: 3.71e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 456 EKQLQGIQIQEAETRDQVKKLQLMLRQANDQLEkTMKEKQELEDFLRQSAEDSSHQISALVLRAQASEVLLEELQQSFSQ 535
Cdd:COG1196 238 EAELEELEAELEELEAELEELEAELAELEAELE-ELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEE 316
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 536 AKRDVQEQMAVLMQSREQVSEELVRLQKDNDSLQGKHslhvslqlaedfilpDTVQVLRELVLKYRENIVHVRTAADHME 615
Cdd:COG1196 317 RLEELEEELAELEEELEELEEELEELEEELEEAEEEL---------------EEAEAELAEAEEALLEAEAELAEAEEEL 381
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 616 EKLKAEILFLKEQIQAEQCLKENLEETLQLEIENCKEEIASISSLKAELERIKVEKGQLESTLREKSQQLESLQEIKVNL 695
Cdd:COG1196 382 EELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL 461
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 149053242 696 EEQLKKETAAKATVEQLMFEEKNKAQRLQTELDVSEQVQRDF 737
Cdd:COG1196 462 LELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
456-762 |
2.08e-08 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 58.02 E-value: 2.08e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 456 EKQLQGIQIQEAETRDQVKKLQLMLRQANDQLEKTMKEKQELEDFLRQSAEDSSH---QISALVLRAQASEVLLEELQQS 532
Cdd:COG1196 210 EKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAEleaELEELRLELEELELELEEAQAE 289
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 533 FSQAKRDV---QEQMAVLMQSREQVSEELVRLQKDNDSLQGKHSLHvslqlaedfilpdtvqvlrelvlkyRENIVHVRT 609
Cdd:COG1196 290 EYELLAELarlEQDIARLEERRRELEERLEELEEELAELEEELEEL-------------------------EEELEELEE 344
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 610 AADHMEEKLKAEILFLKEQIQAEQCLKENLEETLQLEIENCKEEIASISSLKAELERIKVEKGQLESTLREKSQQLESLQ 689
Cdd:COG1196 345 ELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELE 424
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 149053242 690 EIKVNLEEQLKKETAAKATVEQLMFEEKNKAQRLQTELDVSEQVQRDFVKLSQTLQVQLERIRQADSLERIRA 762
Cdd:COG1196 425 ELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLL 497
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
13-740 |
3.13e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 57.37 E-value: 3.13e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 13 NTKQEAIDEVKRQWREEVASLQAVMKETVRDYEHQFH--LRLEQERAQWAQYRESADREIADLRRRLSEGQEE-ENLENE 89
Cdd:TIGR02168 294 ANEISRLEQQKQILRERLANLERQLEELEAQLEELESklDELAEELAELEEKLEELKEELESLEAELEELEAElEELESR 373
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 90 MKKAQEDAEKLRSVVMPMEKEIAALKDKLTEAEDKIKELEASKVKELNHYLEAEKSCrtdLEMYVAVLNTQKSVLQEDAE 169
Cdd:TIGR02168 374 LEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKL---EEAELKELQAELEELEEELE 450
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 170 KLRKELHEVCHLLEQERQQHNQLKHTWQKANDQFLESQRLLmRDMQRMEIVLTSEQLRQVEELKKKDQEEDEQQRInkgK 249
Cdd:TIGR02168 451 ELQEELERLEEALEELREELEEAEQALDAAERELAQLQARL-DSLERLQENLEGFSEGVKALLKNQSGLSGILGVL---S 526
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 250 DNKKIDTEEEVKIPVVC-----ALTQEESSTPLSNEEEHLDSTHGSVHSLDADLLLPSGDPFSKSDNDMFKEGLrrAQST 324
Cdd:TIGR02168 527 ELISVDEGYEAAIEAALggrlqAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGF--LGVA 604
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 325 DSLGTSSSLQSKALGY----------------NYKAKSAGNLDESDFGPLVGADSV----SENFDTVSLG--------SL 376
Cdd:TIGR02168 605 KDLVKFDPKLRKALSYllggvlvvddldnaleLAKKLRPGYRIVTLDGDLVRPGGVitggSAKTNSSILErrreieelEE 684
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 377 QMPSGFMLTKDQERAIKAMTPEQEETASLLSSVTQGMESAYVSPSGY---LLVSETEWNLLQKEVHNAGNKLGRRCDMCS 453
Cdd:TIGR02168 685 KIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALrkdLARLEAEVEQLEERIAQLSKELTELEAEIE 764
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 454 NYEKQLQGIQIQEAETRDQVKKLQLMLRQANDQLEKTMKEKQELEDFLRQSAEDsshqISALVLRAQASEVLLEELQQSF 533
Cdd:TIGR02168 765 ELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEE----AANLRERLESLERRIAATERRL 840
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 534 ---SQAKRDVQEQMAVLMQSREQVSEELVRLQKDNDSLQ---GKHSLHVSLQLAEDFILPDTVQVLRELVLKYRENIVHV 607
Cdd:TIGR02168 841 edlEEQIEELSEDIESLAAEIEELEELIEELESELEALLnerASLEEALALLRSELEELSEELRELESKRSELRRELEEL 920
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 608 RTAADHME---EKLKAEILFLKEQIQAEQCLKENLEETLQLEIEnckeeiASISSLKAELERIKVEKGQLESTLREKSQQ 684
Cdd:TIGR02168 921 REKLAQLElrlEGLEVRIDNLQERLSEEYSLTLEEAEALENKIE------DDEEEARRRLKRLENKIKELGPVNLAAIEE 994
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*.
gi 149053242 685 LESLQEIKVNLEEQLKKETAAKATVEQLMfEEKNKAQRLQTeLDVSEQVQRDFVKL 740
Cdd:TIGR02168 995 YEELKERYDFLTAQKEDLTEAKETLEEAI-EEIDREARERF-KDTFDQVNENFQRV 1048
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
467-756 |
5.36e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 53.53 E-value: 5.36e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 467 AETRDQVKKLQLMLRQANDQLEKTMKEKQELEDFLRQSAEDSSHQISALVLRAQASEVLLEELQQSFSQAKRdVQEQMAV 546
Cdd:TIGR02169 180 EEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEE-ELEKLTE 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 547 LMQSREQVSEELVRLQK----------DNDSLQGK---HSLHVSLQLAEDFI--LPDTVQVLRELVLKYRENIVHVRTAA 611
Cdd:TIGR02169 259 EISELEKRLEEIEQLLEelnkkikdlgEEEQLRVKekiGELEAEIASLERSIaeKERELEDAEERLAKLEAEIDKLLAEI 338
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 612 DHMEEKLKAEILfLKEQIQAEQCLKENLEETLQLEIENCKEEIAS----ISSLKAELERIKVEKGQLESTLREKSQQLES 687
Cdd:TIGR02169 339 EELEREIEEERK-RRDKLTEEYAELKEELEDLRAELEEVDKEFAEtrdeLKDYREKLEKLKREINELKRELDRLQEELQR 417
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 149053242 688 LQEIKVNLEEQLK----KETAAKATVEQLMFEEKNKAQRLQTELDVSEQVQRDFVKLSQTLQVQLERIRQADS 756
Cdd:TIGR02169 418 LSEELADLNAAIAgieaKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQR 490
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
51-245 |
1.02e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 52.63 E-value: 1.02e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 51 RLEQERAQWAQYRESADREIADLRRRLSEGQEE-ENLENEMKKAQEDAEKLRSVVMPMEKEIAALKDKLTEAEDKIKELE 129
Cdd:COG1196 243 ELEAELEELEAELEELEAELAELEAELEELRLElEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELE 322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 130 ASKVKELNHYLEAEKScrtdlemyVAVLNTQKSVLQEDAEKLRKELHEVCHLLEQERQQHNQLKHTWQKANDQFLESQRL 209
Cdd:COG1196 323 EELAELEEELEELEEE--------LEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRA 394
|
170 180 190
....*....|....*....|....*....|....*.
gi 149053242 210 LMRDMQRMEIVLTSEQLRQVEELKKKDQEEDEQQRI 245
Cdd:COG1196 395 AAELAAQLEELEEAEEALLERLERLEEELEELEEAL 430
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
467-708 |
7.33e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 48.99 E-value: 7.33e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 467 AETRDQVKKLQLMLRQANDQLEKTMKEKQELEDFLRQSAEDSSHQISALVLRAQASEVLLEELQQSFSQAKRDVQEQMAV 546
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 547 LMQSREQVSEELVRLQKdndslQGKHSLHVSLQLAEDFilpdtVQVLRELVLkYRENIVHVRTAADHMEEKLkAEILFLK 626
Cdd:COG4942 99 LEAQKEELAELLRALYR-----LGRQPPLALLLSPEDF-----LDAVRRLQY-LKYLAPARREQAEELRADL-AELAALR 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 627 EQIQAEQCLKENLEETLQLEIENCKEEIASISSLKAELERikvEKGQLESTLREKSQQLESLQEIKVNLEEQLKKETAAK 706
Cdd:COG4942 167 AELEAERAELEALLAELEEERAALEALKAERQKLLARLEK---ELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243
|
..
gi 149053242 707 AT 708
Cdd:COG4942 244 PA 245
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
615-763 |
1.25e-05 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 48.78 E-value: 1.25e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 615 EEKLKAEILFLKEQIQAEQCLKENLEETLQLEIENCKEEIASISSLKAELERIKVEKGQLESTLREKSQQLESLQEIKVN 694
Cdd:COG1196 290 EYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE 369
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 149053242 695 LEEQLKKETAAKATVEQLMFEEKNKAQRLQTELDVSEQVQRDFVKLSQTLQVQLERIRQADSLERIRAI 763
Cdd:COG1196 370 AEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEE 438
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
24-273 |
2.19e-05 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 48.01 E-value: 2.19e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 24 RQWREEVASLQAVMKETVRDYEhqfhlRLEQERAQWAQYRESADREIADLRRRLSEGQEEEN-LENEMKKAQEDAEKLRS 102
Cdd:COG1196 235 RELEAELEELEAELEELEAELE-----ELEAELAELEAELEELRLELEELELELEEAQAEEYeLLAELARLEQDIARLEE 309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 103 VVMPMEKEIAALKDKLTEAEDKIKELEASKVKELNHYLEAEKSCRTDLEMYVAVLNTQKSVLQEDAEKLRKELHEVCHLL 182
Cdd:COG1196 310 RRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELL 389
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 183 EQERQQHNQlkhtwQKANDQFLESQRLLMRDMQRMEIVLTSEQLRQVEELKKKDQEEDEQQRINKgKDNKKIDTEEEVKI 262
Cdd:COG1196 390 EALRAAAEL-----AAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAE-EEAELEEEEEALLE 463
|
250
....*....|.
gi 149053242 263 PVVCALTQEES 273
Cdd:COG1196 464 LLAELLEEAAL 474
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
467-700 |
3.86e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 47.37 E-value: 3.86e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 467 AETRDQVKKLQLMLRQANDQLEKTMKEKQELE---DFLRQSAEDSSHQISALVLRAQasevLLEELQQSFSQAKRDVQEQ 543
Cdd:TIGR02169 670 RSEPAELQRLRERLEGLKRELSSLQSELRRIEnrlDELSQELSDASRKIGEIEKEIE----QLEQEEEKLKERLEELEED 745
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 544 MAVLMQSREQVSEELVRLQKDNDSLQGK-HSLHVSLQLAEDFILPDTVQVLRELVLKYRENIVHVRTAADHMEEKLKA-- 620
Cdd:TIGR02169 746 LSSLEQEIENVKSELKELEARIEELEEDlHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRlt 825
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 621 ---------------EILFLKEQIQAEQCLKENLE---ETLQLEIENCKEEI-----------ASISSLKAELERIKVEK 671
Cdd:TIGR02169 826 lekeylekeiqelqeQRIDLKEQIKSIEKEIENLNgkkEELEEELEELEAALrdlesrlgdlkKERDELEAQLRELERKI 905
|
250 260
....*....|....*....|....*....
gi 149053242 672 GQLESTLREKSQQLESLQEIKVNLEEQLK 700
Cdd:TIGR02169 906 EELEAQIEKKRKRLSELKAKLEALEEELS 934
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
14-250 |
1.29e-04 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 45.70 E-value: 1.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 14 TKQEAIDEVKRQWREEVASLQAVMKETVRDYEHQFHLRLEQERAQwaQYRESADREIADLRRRLSE-GQEEENLENEMKK 92
Cdd:COG1196 271 ELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELE--ERLEELEEELAELEEELEElEEELEELEEELEE 348
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 93 AQEDAEKLrsvvmpmEKEIAALKDKLTEAEDKIKELEASKVKELNHYLEAEKScRTDLEMYVAVLNTQKSVLQEDAEKLR 172
Cdd:COG1196 349 AEEELEEA-------EAELAEAEEALLEAEAELAEAEEELEELAEELLEALRA-AAELAAQLEELEEAEEALLERLERLE 420
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 149053242 173 KELHEVCHLLEQERQQHNQLKHTWQKANDQFLESQRLLMRDMQRMEIVLTSEQLRQVEELKKKDQEEDEQQRINKGKD 250
Cdd:COG1196 421 EELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLE 498
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
50-252 |
2.32e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 45.13 E-value: 2.32e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 50 LRLEQERAQWAQYRESADREIADLRRRLSEGQEEENLENEMKKAQEDAEKLRSVVMPMEKEIAALKDKLTEAEDKIKELE 129
Cdd:PTZ00121 1557 LKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVE 1636
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 130 ASKVKELNHYLEAEKSCRTDLEMYVavlntQKSVLQEDAEKLRKELHEVCHLLEQERQQHNQLKHTWQKANdQFLESQRL 209
Cdd:PTZ00121 1637 QLKKKEAEEKKKAEELKKAEEENKI-----KAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAK-KAEELKKK 1710
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 149053242 210 LMRDMQRMEIVLTSEQLR--QVEELKKKDQEED---EQQRINKGKDNK 252
Cdd:PTZ00121 1711 EAEEKKKAEELKKAEEENkiKAEEAKKEAEEDKkkaEEAKKDEEEKKK 1758
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
84-369 |
4.17e-04 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 43.88 E-value: 4.17e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 84 ENLENEMKKAQEDAEKLRSvvmpmeKEIAAL-KDKLTEAEDKIKELEASKVKELNHYLEAEKSCRTDlemyvaVLNTQKS 162
Cdd:PTZ00108 1105 EKLNAELEKKEKELEKLKN------TTPKDMwLEDLDKFEEALEEQEEVEEKEIAKEQRLKSKTKGK------ASKLRKP 1172
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 163 VLQEDAEKLR-KELHEVCHLLEQERQQHNQLKHTWQKANDQFLESQRLLMRDMQRMEIVLTSEQLRQVEELKKKDQEEDE 241
Cdd:PTZ00108 1173 KLKKKEKKKKkSSADKSKKASVVGNSKRVDSDEKRKLDDKPDNKKSNSSGSDQEDDEEQKTKPKKSSVKRLKSKKNNSSK 1252
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 242 QQRINKGKDNKKIDTEEEVKIPV----VCALTQEESSTPLSNEEEHLDSTHGSVHSLDADLLLPSGDPFSKSdNDMFKEG 317
Cdd:PTZ00108 1253 SSEDNDEFSSDDLSKEGKPKNAPkrvsAVQYSPPPPSKRPDGESNGGSKPSSPTKKKVKKRLEGSLAALKKK-KKSEKKT 1331
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 149053242 318 LRRAQSTDSLGTSSSLQSKALGYNYKAKSAGNLDESDFGPLVGADSVSENFD 369
Cdd:PTZ00108 1332 ARKKKSKTRVKQASASQSSRLLRRPRKKKSDSSSEDDDDSEVDDSEDEDDED 1383
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
54-247 |
4.20e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 43.60 E-value: 4.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 54 QERAQWAQYRESADREIADLRRRLSEGQ-EEENLENEMKKAQEDAEKLRSVVMPMEKEIAALKDKLTEAEDKIKELEASK 132
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKkEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 133 VKELNHYLE----AEKSCR-------------TDLEMYVAVLNTQKSVLQEDAEKLRKELHEvchlLEQERQQHNQLKHT 195
Cdd:COG4942 100 EAQKEELAEllraLYRLGRqpplalllspedfLDAVRRLQYLKYLAPARREQAEELRADLAE----LAALRAELEAERAE 175
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 149053242 196 WQKANDQFLESQRLLMRDMQRMEIVLTSEQLRQVEELKKKDQEEDEQQRINK 247
Cdd:COG4942 176 LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEA 227
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1-261 |
4.43e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 43.90 E-value: 4.43e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 1 MENIKAIATVSENTKQE--AIDEVKRQWREEVASLQAVMKETVRDYEHQFHLRLEQERAQWAQYRESADREIADLRRRL- 77
Cdd:TIGR02169 743 EEDLSSLEQEIENVKSElkELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLn 822
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 78 SEGQEEENLENEMKKAQEDAEKLRSVVMPMEKEIAALKDKLTEAEDKIKELEAsKVKELNHYLEAEKSCRTDLEmyvavl 157
Cdd:TIGR02169 823 RLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEA-ALRDLESRLGDLKKERDELE------ 895
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 158 nTQKSVLQEDAEKLRKElhevchlLEQERQQHNQLKHTWQKANDQFLESQRLLMRDMQRMEIVLTSEQLrqVEELKKKDQ 237
Cdd:TIGR02169 896 -AQLRELERKIEELEAQ-------IEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDV--QAELQRVEE 965
|
250 260
....*....|....*....|....
gi 149053242 238 EEDEQQRINkgkdNKKIDTEEEVK 261
Cdd:TIGR02169 966 EIRALEPVN----MLAIQEYEEVL 985
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
595-774 |
4.58e-04 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 43.77 E-value: 4.58e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 595 ELVLKYRENIVHVRTAADHMEEKLKAEIlflkEQIQAEQCLKENLEETLQLEIENCKEEI----ASISSLKAELERIKVE 670
Cdd:COG1196 228 ELLLLKLRELEAELEELEAELEELEAEL----EELEAELAELEAELEELRLELEELELELeeaqAEEYELLAELARLEQD 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 671 KGQLESTLREKSQQLESLQEIKVNLEEQLKKETAAKATVEQLMFEEKNKAQRLQTELDVSEQVQRDFVKLSQTLQVQLER 750
Cdd:COG1196 304 IARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEE 383
|
170 180
....*....|....*....|....
gi 149053242 751 IRQADSLERIRAILNDTKLTDINQ 774
Cdd:COG1196 384 LAEELLEALRAAAELAAQLEELEE 407
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
608-775 |
5.21e-04 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 43.77 E-value: 5.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 608 RTAADHMEEKLKAEILFLKEQIQAEQCLKENLEETLQLEIENCKEEIASISSLKAELERIKVEKGQLESTLREKSQQLES 687
Cdd:COG1196 255 LEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEE 334
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 688 LQEIKVNLEEQL----KKETAAKATVEQLMFEEKNKAQRLQTELDVSEQVQRDFVKLSQTLQVQLERIRQADSLERIRAI 763
Cdd:COG1196 335 LEEELEELEEELeeaeEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLE 414
|
170
....*....|..
gi 149053242 764 LNDTKLTDINQL 775
Cdd:COG1196 415 RLERLEEELEEL 426
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
53-765 |
7.46e-04 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 43.04 E-value: 7.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 53 EQERAQWAQYRESADREIADLRRRLSEGQEE-ENLENEMKKAQEDAEKLRSVVMPMEKEIAALKDKLTEAEDKIKELEAS 131
Cdd:pfam02463 285 EEELKLLAKEEEELKSELLKLERRKVDDEEKlKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKL 364
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 132 KVKELNHYLEAEKSCRTDLEMyvavLNTQKSVLQEDAEKLRKELHEVCHLLEQERQQHNQLKHTWQKANDQFLESQRLLm 211
Cdd:pfam02463 365 QEKLEQLEEELLAKKKLESER----LSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESI- 439
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 212 rDMQRMEIVLTSEQLRQVEELKKKDQEEDEQQRINKGKDNKKidTEEEVKIPVVCALTQEESSTPLSNEEEHLDSTHGSV 291
Cdd:pfam02463 440 -ELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLV--KLQEQLELLLSRQKLEERSQKESKARSGLKVLLALI 516
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 292 HSLDADLLLPSGDPFSKSDNDMFKEGLRRAQSTDSLGTSSSLQSKALGYNYKAKSAGNLDESDFGPLVGADSVSENFDTV 371
Cdd:pfam02463 517 KDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAV 596
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 372 SLGSLQMPSGFMLTKDQERAIKAMTPEQEETASLLSSVTQGMESAYVSPSGYLLVSETEWNLLQKEVHNAGNKLGRRCDM 451
Cdd:pfam02463 597 LEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELL 676
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 452 CSNYEKQLQGIQIQEAETRDQVKKLQLMLRQANDQLEKTMKEKQELEDFLRQSAEDSSHQIsaLVLRAQASEVLLEELQQ 531
Cdd:pfam02463 677 EIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEE--LKLLKQKIDEEEEEEEK 754
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 532 SFSQAKRDVQEQMAVLMQSREQVSEELVRLQKDNDSLQGKHSLHVSLQLAEdfilpdTVQVLRELVLKYRENIVHVRTAA 611
Cdd:pfam02463 755 SRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRA------LEEELKEEAELLEEEQLLIEQEE 828
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 612 DHMEEKLKAEILFLKEQIQAEQCLKENLEETLQLEIENCKEEIASISSLKAELERIKVEKGQLESTLREKSQQLESLQEI 691
Cdd:pfam02463 829 KIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQK 908
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 149053242 692 KVNLEEQLKKETAAKATVEQLMFEEKNKAQRLQTELDVSEQVQRDFVKLSQTLQVQLERIRQADSLERIRAILN 765
Cdd:pfam02463 909 LNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEE 982
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
515-762 |
7.72e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 42.44 E-value: 7.72e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 515 LVLRAQASEVLLEELQQsfsqAKRDVQEQMAVLMQSREQVSEELVRLQKDNDSLQGKHSLhvslqlaedfiLPDTVQVLR 594
Cdd:COG4942 11 LALAAAAQADAAAEAEA----ELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAA-----------LARRIRALE 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 595 ELVLKYRENIVHVRTAADHMEEKLKAEILFLKEQIQAEQCLKENLEETLQLEIENCKEEIASISSLKAELERIKVEKGQL 674
Cdd:COG4942 76 QELAALEAELAELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEEL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 675 ESTLREKSQQLESLQEIKVNLEEQLKKETAAKATVEQLMFEEKNKAQRLQTELDVSEQVQRDFVKLSQTLQVQLERIRQA 754
Cdd:COG4942 156 RADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
|
....*...
gi 149053242 755 DSLERIRA 762
Cdd:COG4942 236 AAAAAERT 243
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
3-191 |
8.17e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 42.98 E-value: 8.17e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 3 NIKAIATVSEntKQEAIDEVKRQWREEVASLQAVMKETVRdyehQFHLRLEQERAQWAQYR-ESADREIADL---RRRLS 78
Cdd:COG4913 608 NRAKLAALEA--ELAELEEELAEAEERLEALEAELDALQE----RREALQRLAEYSWDEIDvASAEREIAELeaeLERLD 681
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 79 EGQEE-ENLENEMKKAQEDAEKLRSVVMPMEKEIAALKDKLTEAEDKIKELE-----ASKVKELNHYLEAEKSCRTDLEM 152
Cdd:COG4913 682 ASSDDlAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQdrleaAEDLARLELRALLEERFAAALGD 761
|
170 180 190
....*....|....*....|....*....|....*....
gi 149053242 153 yvAVLNTQKSVLQEDAEKLRKELHEVCHLLEQERQQHNQ 191
Cdd:COG4913 762 --AVERELRENLEERIDALRARLNRAEEELERAMRAFNR 798
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
67-196 |
8.29e-04 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 42.92 E-value: 8.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 67 DREIADLRRRLSEGQEEENLENEMKKAQEDAE--KLRSVVMPMEKEIAALKDKLTEAEDKIKELEAsKVKELNhyLEAEK 144
Cdd:COG2433 383 EELIEKELPEEEPEAEREKEHEERELTEEEEEirRLEEQVERLEAEVEELEAELEEKDERIERLER-ELSEAR--SEERR 459
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 149053242 145 SCRTDLEMyvavlntqkSVLQEDAEKLRKELHEVCHLLEQERQQHNQLKHTW 196
Cdd:COG2433 460 EIRKDREI---------SRLDREIERLERELEEERERIEELKRKLERLKELW 502
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
2-143 |
9.03e-04 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 42.54 E-value: 9.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 2 ENIKAIATVSENTKQEAIDEVKRQWREEVASLQAVMKETVRDYEHQFHlRLEQERAQWAQYRESADREIADLRRRLSEGQ 81
Cdd:COG2433 376 LSIEEALEELIEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVE-RLEAEVEELEAELEEKDERIERLERELSEAR 454
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 149053242 82 EEENLEnemkkAQEDAEklrsvVMPMEKEIAALKDKLTEAEDKIKELEaSKVKELNHYLEAE 143
Cdd:COG2433 455 SEERRE-----IRKDRE-----ISRLDREIERLERELEEERERIEELK-RKLERLKELWKLE 505
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
616-770 |
1.08e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 42.74 E-value: 1.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 616 EKLKAEILFLKEQI-QAEQCLKENLEETLQLEIENCK------EEIASISSLKAELERIKVEKGQLESTLREKSQQLESL 688
Cdd:TIGR02168 680 EELEEKIEELEEKIaELEKALAELRKELEELEEELEQlrkeleELSRQISALRKDLARLEAEVEQLEERIAQLSKELTEL 759
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 689 QEIKVNLEEQLKKETAAKATVEQLMFEEKNKAQRLQTELDVSEQVQRDFVKlsqtlQVQLERIRQADSLERIRAILNDTK 768
Cdd:TIGR02168 760 EAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRA-----ELTLLNEEAANLRERLESLERRIA 834
|
..
gi 149053242 769 LT 770
Cdd:TIGR02168 835 AT 836
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
609-774 |
1.13e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 42.74 E-value: 1.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 609 TAADHMEEKLKAEILFLKEQIQAEQCLKENLEETLQLEIENCKEEIASISSLKAELERIKVEKGQLESTLREKSQQLESL 688
Cdd:TIGR02168 249 KEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEEL 328
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 689 QEIKVNLEEQLKKETAAKATVEQLMFEEKNKAQRLQTELDVSEQVQRDFVKLSQTLQVQLERIRQADSLERIRAILNDTK 768
Cdd:TIGR02168 329 ESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEAR 408
|
....*.
gi 149053242 769 LTDINQ 774
Cdd:TIGR02168 409 LERLED 414
|
|
| FPP |
pfam05911 |
Filament-like plant protein, long coiled-coil; FPP is a family of long coiled-coil plant ... |
619-751 |
1.21e-03 |
|
Filament-like plant protein, long coiled-coil; FPP is a family of long coiled-coil plant proteins that are filament-like. It interacts with the nuclear envelope-associated protein, MAF1, the WPP family pfam13943.
Pssm-ID: 461778 [Multi-domain] Cd Length: 859 Bit Score: 42.35 E-value: 1.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 619 KAEILFLKEQIQAEQCLKENLEETLQLEIENCKEEIA-------SISSLKAELERIKVEKGQLEStlreksqQLESLQEI 691
Cdd:pfam05911 680 TEENKRLKEEFEQLKSEKENLEVELASCTENLESTKSqlqeseqLIAELRSELASLKESNSLAET-------QLKCMAES 752
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 692 KVNLEEQLkkeTAAKATVEQLmfeeKNKAQRLQTELDVSEQVQRDFVKLSQTLQVQLERI 751
Cdd:pfam05911 753 YEDLETRL---TELEAELNEL----RQKFEALEVELEEEKNCHEELEAKCLELQEQLERN 805
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
67-188 |
1.65e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 40.68 E-value: 1.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 67 DREIADLRRRLSEGQEE-ENLENEMKKAQEDAEKLRSVVMPMEKEIAALKDKLTEAEDKIKELE-----ASKVKELN--- 137
Cdd:COG1579 16 DSELDRLEHRLKELPAElAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEeqlgnVRNNKEYEalq 95
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 149053242 138 HYLEAEKSCRTDLEMYVAVLNTQKSVLQEDAEKLRKELHEVCHLLEQERQQ 188
Cdd:COG1579 96 KEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAE 146
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
524-754 |
1.76e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 41.29 E-value: 1.76e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 524 VLLEELQQSFSQAKRDVQEQMAVLMQSREQVSEELVRLQKDNDSLQGKhslhvsLQLAEDFI--LPDTVQVLRELVLKYR 601
Cdd:COG4942 9 LLLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQ------LAALERRIaaLARRIRALEQELAALE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 602 ENIVHVRTAADHMEEKLKAEILFLKEQIQAEQCLKENLEETLQLEIENCKEEIASISSLKA-------ELERIKVEKGQL 674
Cdd:COG4942 83 AELAELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYlaparreQAEELRADLAEL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 675 ESTLREKSQQLESLQEIKVNLEEQLKKETAAKATVEQLMFEEKNKAQRLQTELDVSEQVQRDFVKLSQTLQVQLERIRQA 754
Cdd:COG4942 163 AALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
17-193 |
2.00e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 41.82 E-value: 2.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 17 EAIDEVKRQWREEVASLQAV--MKETVRDYEHQFHLRL-EQERAQWAQYRESADREIADLRRRLSEGQEE-ENLENEMKK 92
Cdd:COG4913 255 EPIRELAERYAAARERLAELeyLRAALRLWFAQRRLELlEAELEELRAELARLEAELERLEARLDALREElDELEAQIRG 334
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 93 AQEDAEKlrsvvmPMEKEIAALKDKLTEAEDKIKELEAsKVKELNHYLEAEkscRTDLEMYVAVLNTQKSVLQEDAEKLR 172
Cdd:COG4913 335 NGGDRLE------QLEREIERLERELEERERRRARLEA-LLAALGLPLPAS---AEEFAALRAEAAALLEALEEELEALE 404
|
170 180
....*....|....*....|.
gi 149053242 173 KELHEVCHLLEQERQQHNQLK 193
Cdd:COG4913 405 EALAEAEAALRDLRRELRELE 425
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
470-690 |
2.04e-03 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 41.81 E-value: 2.04e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 470 RDQVKKLQLMLRQANDQLEKTMKEKQELEDFL--------RQSAEDSSHQISALVLRAQASEVLLEELQQSFSQAK---- 537
Cdd:PLN02939 48 KKRGKNIAPKQRSSNSKLQSNTDENGQLENTSlrtvmelpQKSTSSDDDHNRASMQRDEAIAAIDNEQQTNSKDGEqlsd 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 538 ----------RDVQEQMAVLMQSREQVSEELVRLQKDNDSLQGKHSLhVSLQLAEDFILPDT-------VQVLRELVLKY 600
Cdd:PLN02939 128 fqledlvgmiQNAEKNILLLNQARLQALEDLEKILTEKEALQGKINI-LEMRLSETDARIKLaaqekihVEILEEQLEKL 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 601 RENIVHVRTAADHMEEKLKAEILFLKEqiqaeqclkENLeeTLQLEIENCKEEIASISSLKAELERIKVEKGQLESTLRE 680
Cdd:PLN02939 207 RNELLIRGATEGLCVHSLSKELDVLKE---------ENM--LLKDDIQFLKAELIEVAETEERVFKLEKERSLLDASLRE 275
|
250
....*....|
gi 149053242 681 KSQQLESLQE 690
Cdd:PLN02939 276 LESKFIVAQE 285
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
387-752 |
2.20e-03 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 41.64 E-value: 2.20e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 387 DQERAIKAMTPEQEETASLLSSVTQGMESAYVSPSGYLLVSETEWNLLQKEVHNAGNKLGRRCDMCSNYEKQLQGIQIQE 466
Cdd:pfam15921 321 DLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQN 400
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 467 AETRDQVKKLQLMLRQANDQLEKTMKEKQELEDFLRQSAEDSSHQISALVLRAQASEVLLEELQQSFSQakrdVQEQMAV 546
Cdd:pfam15921 401 KRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQ----LESTKEM 476
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 547 LMQSREQVSEELVRLQKDNDSLQgkhSLHVSLQLAEDFILPDTVQV--LRELVLKYRENIVHVRTAADHM---EEKLKAE 621
Cdd:pfam15921 477 LRKVVEELTAKKMTLESSERTVS---DLTASLQEKERAIEATNAEItkLRSRVDLKLQELQHLKNEGDHLrnvQTECEAL 553
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 622 ILFLKEQIQAEQCLKENLEETLQL-----------EIENCKEEiASISSLKAELERIKVEKGQLESTLREKSQQLESLQE 690
Cdd:pfam15921 554 KLQMAEKDKVIEILRQQIENMTQLvgqhgrtagamQVEKAQLE-KEINDRRLELQEFKILKDKKDAKIRELEARVSDLEL 632
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 149053242 691 IKVNL----EEQLKKETAAKATVEQLMFEEKNKAQRLQTELDVSEQVQRDFVKLSQTLQVQLERIR 752
Cdd:pfam15921 633 EKVKLvnagSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLK 698
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
16-285 |
2.26e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 41.59 E-value: 2.26e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 16 QEAIDEVKRQ---WREEVASLQAVMKE--TVRDYEHQFHLRLEQERAQWAQYRESADREIADLRRRLSEGQEE-ENLENE 89
Cdd:TIGR02169 680 RERLEGLKRElssLQSELRRIENRLDElsQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEiENVKSE 759
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 90 MKKaqedaeklrsvvmpMEKEIAALKDKLTEAEDKIKELEA----SKVKELNHYLEAEKSCRTDLEMYVavlntqksvlq 165
Cdd:TIGR02169 760 LKE--------------LEARIEELEEDLHKLEEALNDLEArlshSRIPEIQAELSKLEEEVSRIEARL----------- 814
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 166 EDAEKLRKELHEVCHLLEQERQQHNQLKHTWQ---KANDQFLESQRLLMRDMQRmEIVLTSEQLRQVEELKKKDQEEDEQ 242
Cdd:TIGR02169 815 REIEQKLNRLTLEKEYLEKEIQELQEQRIDLKeqiKSIEKEIENLNGKKEELEE-ELEELEAALRDLESRLGDLKKERDE 893
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 149053242 243 QRINKGKDNKKIDT-EEEVKIPVVCALTQEESSTPLSNEEEHLD 285
Cdd:TIGR02169 894 LEAQLRELERKIEElEAQIEKKRKRLSELKAKLEALEEELSEIE 937
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
350-573 |
3.30e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 41.05 E-value: 3.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 350 LDESDFGPLvgADSVSENFDTVSLGSLQMpsgfmltKDQERAIKAMTPEQEETASLLSSVTQGMESAYVSPSGYLLVSET 429
Cdd:COG4913 218 LEEPDTFEA--ADALVEHFDDLERAHEAL-------EDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQR 288
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 430 EWNLLQKEVHNAGNKLGRRcdmcsnyEKQLQGIQIQEAETRDQVKKLQLMLRQAN----DQLEKTMKEKQELEDFLRQSA 505
Cdd:COG4913 289 RLELLEAELEELRAELARL-------EAELERLEARLDALREELDELEAQIRGNGgdrlEQLEREIERLERELEERERRR 361
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 149053242 506 EDSSHQISALVLRAQASEVLLEELQ-------QSFSQAKRDVQEQMAVLMQSREQVSEELVRLQKDNDSLQGKHS 573
Cdd:COG4913 362 ARLEALLAALGLPLPASAEEFAALRaeaaallEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKS 436
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
74-261 |
3.77e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 40.88 E-value: 3.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 74 RRRLSEGQEEENLENEMKKAQEDAEKLRSVVMPMEKEIAALKDKLteAEDKIKELEASKVKELNHYLEAEKSCRTDLEM- 152
Cdd:pfam17380 298 QERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERM--AMERERELERIRQEERKRELERIRQEEIAMEIs 375
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 153 YVAVLNTQKSVLQEDAEKLRKELHEV--CHLLEQERQQHNQLKHTW------QKANDQFLESQRLLMRDMQRMEIVLTSE 224
Cdd:pfam17380 376 RMRELERLQMERQQKNERVRQELEAArkVKILEEERQRKIQQQKVEmeqiraEQEEARQREVRRLEEERAREMERVRLEE 455
|
170 180 190
....*....|....*....|....*....|....*...
gi 149053242 225 QLRQVE-ELKKKDQEEDEQQRINKGKDNKKIDTEEEVK 261
Cdd:pfam17380 456 QERQQQvERLRQQEEERKRKKLELEKEKRDRKRAEEQR 493
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
12-139 |
4.16e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 40.53 E-value: 4.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 12 ENTKQEAIDEVKRQWreevaslqavmketvrdyehqFHLRLEQERaqwaQYREsADREIADLRRRLSegQEEENLENEMk 91
Cdd:PRK12704 52 EAIKKEALLEAKEEI---------------------HKLRNEFEK----ELRE-RRNELQKLEKRLL--QKEENLDRKL- 102
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 149053242 92 kaqEDAEKLRSVVMPMEKEIAALKDKLTEAEDKIKELEASKVKELNHY 139
Cdd:PRK12704 103 ---ELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERI 147
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
615-768 |
4.74e-03 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 40.67 E-value: 4.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 615 EEKLKAEILFLKEQIQAEQ---CLKENLEETLQLeienckeeIASISSLKAELERIKVEKGQLESTLREKSQQLESLQEI 691
Cdd:PRK11281 38 EADVQAQLDALNKQKLLEAedkLVQQDLEQTLAL--------LDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDD 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 692 KVnleeQLKKETAAKATVEQLMfeeknkaQRLQTELDVSEQVQRDFVKL-SQ--TLQVQLERIRQADS-----LERIRAI 763
Cdd:PRK11281 110 ND----EETRETLSTLSLRQLE-------SRLAQTLDQLQNAQNDLAEYnSQlvSLQTQPERAQAALYansqrLQQIRNL 178
|
....*
gi 149053242 764 LNDTK 768
Cdd:PRK11281 179 LKGGK 183
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
456-644 |
5.70e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 39.75 E-value: 5.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 456 EKQLQGIQIQEAETRDQVKKLQLMLRQANDQLEKTMKEKQELEDFLRQSAEDSSHQISALVLRAQASEVLLEELQQSFSQ 535
Cdd:COG4942 54 LKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLD 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 536 AKRDVQeQMAVLMQSREQVSEELVRLQKDNDSLQgkhslhVSLQLAEdfilpDTVQVLRELVLKYRENIVHVRTAADHME 615
Cdd:COG4942 134 AVRRLQ-YLKYLAPARREQAEELRADLAELAALR------AELEAER-----AELEALLAELEEERAALEALKAERQKLL 201
|
170 180
....*....|....*....|....*....
gi 149053242 616 EKLKAEILFLKEQIQAEQCLKENLEETLQ 644
Cdd:COG4942 202 ARLEKELAELAAELAELQQEAEELEALIA 230
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
533-756 |
6.58e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 40.33 E-value: 6.58e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 533 FSQAKRDvqEQMAVLMQSREQVSEELVRLQKDNDSLQGKH---SLHVSLQLAEDFIlPDTVQVLRELVLKYREnIVHVRT 609
Cdd:PRK04863 779 FGRAARE--KRIEQLRAEREELAERYATLSFDVQKLQRLHqafSRFIGSHLAVAFE-ADPEAELRQLNRRRVE-LERALA 854
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 610 AADHMEEKLKAEILFLKEQIQA-EQCLKEN---LEETLQLEIENCKEEIASISSLKAELERIKVEKGQLE---STLREKS 682
Cdd:PRK04863 855 DHESQEQQQRSQLEQAKEGLSAlNRLLPRLnllADETLADRVEEIREQLDEAEEAKRFVQQHGNALAQLEpivSVLQSDP 934
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 149053242 683 QQLESLQEIKVNLEEQLKKETAAKATVEQLM-----FEEKNKAQRLQTELDVSEQVQRDFVKLSQTLQVQLERIRQADS 756
Cdd:PRK04863 935 EQFEQLKQDYQQAQQTQRDAKQQAFALTEVVqrrahFSYEDAAEMLAKNSDLNEKLRQRLEQAEQERTRAREQLRQAQA 1013
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
456-618 |
9.06e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 39.51 E-value: 9.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 456 EKQLQGIQIQEAETRDQVKKLQLMLRQANDQLEK----------------TMKEKQELEDFLRQsAEDSSHQISALVLRA 519
Cdd:COG4913 616 EAELAELEEELAEAEERLEALEAELDALQERREAlqrlaeyswdeidvasAEREIAELEAELER-LDASSDDLAALEEQL 694
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149053242 520 QASEVLLEELQQsfsqAKRDVQEQMAVLMQSREQVSEELVRLQKDNDSLQGKHSLHVSLQLAEDFILPDTVQVLRELVLK 599
Cdd:COG4913 695 EELEAELEELEE----ELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELREN 770
|
170
....*....|....*....
gi 149053242 600 YRENIVHVRTAADHMEEKL 618
Cdd:COG4913 771 LEERIDALRARLNRAEEEL 789
|
|
| |
