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Conserved domains on  [gi|149059162|gb|EDM10169|]
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mitochondrial ribosomal protein S27 (predicted), isoform CRA_c [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
MRP-S27 super family cl25450
Mitochondrial 28S ribosomal protein S27; Members of this family of small ribosomal proteins ...
1-162 1.84e-94

Mitochondrial 28S ribosomal protein S27; Members of this family of small ribosomal proteins possess one of three conserved blocks of sequence found in proteins that stimulate the dissociation of guanine nucleotides from G-proteins, leaving open the possibility that MRP-S27 might be a functional partner of GTP-binding ribosomal proteins.


The actual alignment was detected with superfamily member pfam10037:

Pssm-ID: 462947 [Multi-domain]  Cd Length: 395  Bit Score: 280.87  E-value: 1.84e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149059162    1 MAAPMVRCGMLLARGIAASRLsLAGKRCLLSAAYVDSHQWEAREKEQCHLADLASLMDKAYERKLPVSSLSISRFVDNIS 80
Cdd:pfam10037   1 MAASRIRRALLPARNVTVRPL-LSGRRSLLSAAYVDSKKWESRLKEPQNLADLASEMDKTFERKLPVSSLDVDRFVNNIS 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149059162   81 SREDIDSAEYYLYKFRHSPNCWYLRDWTIHTWIRQCLKYGAPDKALYTLVNKVQYGIFPDNFTFNLLMDYFIKKENYKEN 160
Cdd:pfam10037  80 SREEIDDAEYYLYKLRHSPNCWYLRDWTSHAWIRQCLKYGAPDKALYTLKNKVQYGIFPDNFTFNLLMDSFLKNGDYKSA 159

                  ..
gi 149059162  161 LS 162
Cdd:pfam10037 160 AS 161
 
Name Accession Description Interval E-value
MRP-S27 pfam10037
Mitochondrial 28S ribosomal protein S27; Members of this family of small ribosomal proteins ...
1-162 1.84e-94

Mitochondrial 28S ribosomal protein S27; Members of this family of small ribosomal proteins possess one of three conserved blocks of sequence found in proteins that stimulate the dissociation of guanine nucleotides from G-proteins, leaving open the possibility that MRP-S27 might be a functional partner of GTP-binding ribosomal proteins.


Pssm-ID: 462947 [Multi-domain]  Cd Length: 395  Bit Score: 280.87  E-value: 1.84e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149059162    1 MAAPMVRCGMLLARGIAASRLsLAGKRCLLSAAYVDSHQWEAREKEQCHLADLASLMDKAYERKLPVSSLSISRFVDNIS 80
Cdd:pfam10037   1 MAASRIRRALLPARNVTVRPL-LSGRRSLLSAAYVDSKKWESRLKEPQNLADLASEMDKTFERKLPVSSLDVDRFVNNIS 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149059162   81 SREDIDSAEYYLYKFRHSPNCWYLRDWTIHTWIRQCLKYGAPDKALYTLVNKVQYGIFPDNFTFNLLMDYFIKKENYKEN 160
Cdd:pfam10037  80 SREEIDDAEYYLYKLRHSPNCWYLRDWTSHAWIRQCLKYGAPDKALYTLKNKVQYGIFPDNFTFNLLMDSFLKNGDYKSA 159

                  ..
gi 149059162  161 LS 162
Cdd:pfam10037 160 AS 161
 
Name Accession Description Interval E-value
MRP-S27 pfam10037
Mitochondrial 28S ribosomal protein S27; Members of this family of small ribosomal proteins ...
1-162 1.84e-94

Mitochondrial 28S ribosomal protein S27; Members of this family of small ribosomal proteins possess one of three conserved blocks of sequence found in proteins that stimulate the dissociation of guanine nucleotides from G-proteins, leaving open the possibility that MRP-S27 might be a functional partner of GTP-binding ribosomal proteins.


Pssm-ID: 462947 [Multi-domain]  Cd Length: 395  Bit Score: 280.87  E-value: 1.84e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149059162    1 MAAPMVRCGMLLARGIAASRLsLAGKRCLLSAAYVDSHQWEAREKEQCHLADLASLMDKAYERKLPVSSLSISRFVDNIS 80
Cdd:pfam10037   1 MAASRIRRALLPARNVTVRPL-LSGRRSLLSAAYVDSKKWESRLKEPQNLADLASEMDKTFERKLPVSSLDVDRFVNNIS 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149059162   81 SREDIDSAEYYLYKFRHSPNCWYLRDWTIHTWIRQCLKYGAPDKALYTLVNKVQYGIFPDNFTFNLLMDYFIKKENYKEN 160
Cdd:pfam10037  80 SREEIDDAEYYLYKLRHSPNCWYLRDWTSHAWIRQCLKYGAPDKALYTLKNKVQYGIFPDNFTFNLLMDSFLKNGDYKSA 159

                  ..
gi 149059162  161 LS 162
Cdd:pfam10037 160 AS 161
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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