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Conserved domains on  [gi|228822350|gb|EEM68330|]
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DNA polymerase III subunit gamma/tau [Bacillus thuringiensis serovar berliner ATCC 10792]

Protein Classification

DNA polymerase III subunit gamma/tau( domain architecture ID 11481115)

DNA polymerase III subunit gamma/tau is part of the DNA polymerase III holoenzyme; gamma and tau subunits are isoforms and either one or both may be present in the holoenzyme; gamma interacts with the delta subunit to transfer the beta subunit on the DNA while tau serves as a scaffold to help in the dimerization of the core complex

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK05563 PRK05563
DNA polymerase III subunits gamma and tau; Validated
1-562 0e+00

DNA polymerase III subunits gamma and tau; Validated


:

Pssm-ID: 235505 [Multi-domain]  Cd Length: 559  Bit Score: 931.59  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   1 MSYQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCL 80
Cdd:PRK05563   1 MMYQALYRKWRPQTFEDVVGQEHITKTLKNAIKQGKISHAYLFSGPRGTGKTSAAKIFAKAVNCLNPPDGEPCNECEICK 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  81 GITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPH 160
Cdd:PRK05563  81 AITNGSLMDVIEIDAASNNGVDEIRDIRDKVKYAPSEAKYKVYIIDEVHMLSTGAFNALLKTLEEPPAHVIFILATTEPH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 161 KIPPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDEIVTTEDVLAV 240
Cdd:PRK05563 161 KIPATILSRCQRFDFKRISVEDIVERLKYILDKEGIEYEDEALRLIARAAEGGMRDALSILDQAISFGDGKVTYEDALEV 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 241 TGSVSQQYLGNLVECIRENDVSRALQIIDEMMSKGKDPVRFMEDFIYYYRDMLLYQTSPQLEHMLERVIVDDQFRKLSEE 320
Cdd:PRK05563 241 TGSVSQEALDDLVDAIVEGDVAKALKILEELLDEGKDPNRFIEDLIYYLRDLLLVKTSPELEILDESTENDELFKELSEK 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 321 MQPEVIYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQLCQQFMMQANGTDRLQAIMNRMQQLEKELEQVKKNGVPAGVQQE 400
Cdd:PRK05563 321 LDIERLYRMIDILNDAQQQIKWTNQPRIYLEVALVKLCEQAAASPEYDTELEVLLQRVEQLEQELKQLKAQPVGVAPEQK 400
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 401 vrETRATPKPVRTGSMKIPVGRVNEVLKQAKRQDLEQLKAVWGELLGRLKSYNKVAFAvLLENSEPVAASDDTYVLAFQY 480
Cdd:PRK05563 401 --EKKKEKKKNKKKKYKVPRGKIYKVLKEATRQDLELLKNVWGEILESLKAQRKSLRA-LLVNSEPVAASEDTVVLAFEY 477
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 481 EIHCKMASENREAMDTVEQALFELLSKRLNMIAIPKSEWGKIREDFLQREGGESEESPEKKEDPLIEEAVKLVGQELIEI 560
Cdd:PRK05563 478 EIHFEKAMLDKELNDTIENILSKLLGKSVEIVAVPEDEWQKIREEFLQKHKNEEEEEEEEEELPLIPEAKELFGEDLVEI 557

                 ..
gi 228822350 561 KE 562
Cdd:PRK05563 558 ID 559
 
Name Accession Description Interval E-value
PRK05563 PRK05563
DNA polymerase III subunits gamma and tau; Validated
1-562 0e+00

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235505 [Multi-domain]  Cd Length: 559  Bit Score: 931.59  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   1 MSYQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCL 80
Cdd:PRK05563   1 MMYQALYRKWRPQTFEDVVGQEHITKTLKNAIKQGKISHAYLFSGPRGTGKTSAAKIFAKAVNCLNPPDGEPCNECEICK 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  81 GITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPH 160
Cdd:PRK05563  81 AITNGSLMDVIEIDAASNNGVDEIRDIRDKVKYAPSEAKYKVYIIDEVHMLSTGAFNALLKTLEEPPAHVIFILATTEPH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 161 KIPPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDEIVTTEDVLAV 240
Cdd:PRK05563 161 KIPATILSRCQRFDFKRISVEDIVERLKYILDKEGIEYEDEALRLIARAAEGGMRDALSILDQAISFGDGKVTYEDALEV 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 241 TGSVSQQYLGNLVECIRENDVSRALQIIDEMMSKGKDPVRFMEDFIYYYRDMLLYQTSPQLEHMLERVIVDDQFRKLSEE 320
Cdd:PRK05563 241 TGSVSQEALDDLVDAIVEGDVAKALKILEELLDEGKDPNRFIEDLIYYLRDLLLVKTSPELEILDESTENDELFKELSEK 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 321 MQPEVIYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQLCQQFMMQANGTDRLQAIMNRMQQLEKELEQVKKNGVPAGVQQE 400
Cdd:PRK05563 321 LDIERLYRMIDILNDAQQQIKWTNQPRIYLEVALVKLCEQAAASPEYDTELEVLLQRVEQLEQELKQLKAQPVGVAPEQK 400
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 401 vrETRATPKPVRTGSMKIPVGRVNEVLKQAKRQDLEQLKAVWGELLGRLKSYNKVAFAvLLENSEPVAASDDTYVLAFQY 480
Cdd:PRK05563 401 --EKKKEKKKNKKKKYKVPRGKIYKVLKEATRQDLELLKNVWGEILESLKAQRKSLRA-LLVNSEPVAASEDTVVLAFEY 477
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 481 EIHCKMASENREAMDTVEQALFELLSKRLNMIAIPKSEWGKIREDFLQREGGESEESPEKKEDPLIEEAVKLVGQELIEI 560
Cdd:PRK05563 478 EIHFEKAMLDKELNDTIENILSKLLGKSVEIVAVPEDEWQKIREEFLQKHKNEEEEEEEEEELPLIPEAKELFGEDLVEI 557

                 ..
gi 228822350 561 KE 562
Cdd:PRK05563 558 ID 559
dnaX_nterm TIGR02397
DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ ...
3-358 0e+00

DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ 365 amino acids of the translation of the dnaX gene. The full-length product of the dnaX gene in the model bacterium E. coli is the DNA polymerase III tau subunit. A translational frameshift leads to early termination and a truncated protein subunit gamma, about 1/3 shorter than tau and present in roughly equal amounts. This frameshift mechanism is not necessarily universal for species with DNA polymerase III but appears conserved in the exterme thermophile Thermus thermophilis. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274111 [Multi-domain]  Cd Length: 355  Bit Score: 553.33  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350    3 YQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCLGI 82
Cdd:TIGR02397   1 YQVLARKYRPQTFEDVIGQEHIVQTLKNAIKNGRIAHAYLFSGPRGTGKTSIARIFAKALNCQNGPDGEPCNECESCKEI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   83 TQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHKI 162
Cdd:TIGR02397  81 NSGSSLDVIEIDAASNNGVDDIREILDNVKYAPSSGKYKVYIIDEVHMLSKSAFNALLKTLEEPPEHVVFILATTEPHKI 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  163 PPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDEIVTTEDVLAVTG 242
Cdd:TIGR02397 161 PATILSRCQRFDFKRIPLEDIVERLKKILDKEGIKIEDEALELIARAADGSLRDALSLLDQLISFGNGKITYEDVNELLG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  243 SVSQQYLGNLVECIRENDVSRALQIIDEMMSKGKDPVRFMEDFIYYYRDMLLYQTSPqlEHMLERV-IVDDQFRKLSEEM 321
Cdd:TIGR02397 241 LVDDEKLIELLEAILNKDTAEALKILDEILESGVDPEKFLEDLIEILRDLLLIKKTP--SNLLAVLeSEQEFLKELALKL 318
                         330       340       350
                  ....*....|....*....|....*....|....*..
gi 228822350  322 QPEVIYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQLC 358
Cdd:TIGR02397 319 SLEFLLRLLDILLEALKDLRFSNDPRIWLEMTLLRLL 355
DnaX COG2812
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
1-359 2.71e-175

DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];


Pssm-ID: 442061 [Multi-domain]  Cd Length: 340  Bit Score: 498.56  E-value: 2.71e-175
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   1 MSYQAlyrtwrPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCL 80
Cdd:COG2812    1 MSYQV------PQTFDDVVGQEHVVRTLKNALASGRLAHAYLFTGPRGVGKTTLARILAKALNCENGPTGEPCGECESCR 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  81 GITQGSISDVLEIDA-ASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEP 159
Cdd:COG2812   75 AIAAGSHPDVIEIDAeASNIGVDDIRELIEKVSYAPVEGRYKVYIIDEAHMLTTEAFNALLKTLEEPPPHVVFILATTEP 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 160 HKIPPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYsdeivttedvla 239
Cdd:COG2812  155 QKLLPTILSRCQRFDFRRLPPEEIAEHLAKIAEREGIEIEPEALALIARAADGSMRDALSLLDQAIAF------------ 222
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 240 vtGSVS-QQYLGNLVECIRENDVSRALQIIDEMMSKGKDPVRFMEDFIYYYRDMLLYQTSPQLEHMLERVIVdDQFRKLS 318
Cdd:COG2812  223 --GLLDrRELLLDLLEALLAGDVAALLALAEELAKRGRDLKRFLDDLLSLLRDLLLLKLGPDAELLVNEDER-ERLQELA 299
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|.
gi 228822350 319 EEMQPEVIYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQLCQ 359
Cdd:COG2812  300 RRLSPERLLRAIQILLEARRELERNVNPRLALEMLLLRLAR 340
DNA_pol3_delta2 pfam13177
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ...
20-179 6.49e-55

DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.


Pssm-ID: 433013 [Multi-domain]  Cd Length: 161  Bit Score: 182.80  E-value: 6.49e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   20 GQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCLGITQGSISDVLEIDAASNN 99
Cdd:pfam13177   1 GQPEAIQLLQNSLENGRLSHAYLFSGPEGVGKLELALAFAKALFCEEPGDDLPCGQCRSCRRIESGNHPDLVIIEPEGQS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  100 -GVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHKIPPTIISRCQRFEFRKI 178
Cdd:pfam13177  81 iKIDQIRELQKEFSKSPYEGKKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRCQIIRFKPL 160

                  .
gi 228822350  179 S 179
Cdd:pfam13177 161 S 161
HLD_clamp_pol_III_gamma_tau cd18137
helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit ...
178-242 1.09e-24

helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit gamma/tau is part of the DNA polymerase III holoenzyme. Gamma and tau subunits are isoforms, both containing the helical lid domain. Gamma interacts with the delta subunit to transfer the beta subunit on the DNA while tau serves as a scaffold to help in the dimerization of the core complex. Both are members of the clamp-loader clade of the AAA+ superfamily.


Pssm-ID: 350839 [Multi-domain]  Cd Length: 65  Bit Score: 97.19  E-value: 1.09e-24
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 228822350 178 ISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDEIVTTEDVLAVTG 242
Cdd:cd18137    1 ISVEDIVGRLAHILEKEGIEIEDEALELIARAAEGSMRDALSLLDQAIAFGGGRVTLDDVREMLG 65
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
41-178 3.71e-09

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 55.46  E-value: 3.71e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350    41 YLFSGPRGTGKTTIAKVFAKAINCEHAPVAEpCNECPSCLGITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPsaveY 120
Cdd:smart00382   5 ILIVGPPGSGKTTLARALARELGPPGGGVIY-IDGEDILEEVLDQLLLIIVGGKKASGSGELRLRLALALARKLK----P 79
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 228822350   121 KVYIIDEVHMLSMGAFNALL--------KTLEEPPGHVIFILATTEPHKIPPTIISR--CQRFEFRKI 178
Cdd:smart00382  80 DVLILDEITSLLDAEQEALLllleelrlLLLLKSEKNLTVILTTNDEKDLGPALLRRrfDRRIVLLLI 147
 
Name Accession Description Interval E-value
PRK05563 PRK05563
DNA polymerase III subunits gamma and tau; Validated
1-562 0e+00

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235505 [Multi-domain]  Cd Length: 559  Bit Score: 931.59  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   1 MSYQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCL 80
Cdd:PRK05563   1 MMYQALYRKWRPQTFEDVVGQEHITKTLKNAIKQGKISHAYLFSGPRGTGKTSAAKIFAKAVNCLNPPDGEPCNECEICK 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  81 GITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPH 160
Cdd:PRK05563  81 AITNGSLMDVIEIDAASNNGVDEIRDIRDKVKYAPSEAKYKVYIIDEVHMLSTGAFNALLKTLEEPPAHVIFILATTEPH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 161 KIPPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDEIVTTEDVLAV 240
Cdd:PRK05563 161 KIPATILSRCQRFDFKRISVEDIVERLKYILDKEGIEYEDEALRLIARAAEGGMRDALSILDQAISFGDGKVTYEDALEV 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 241 TGSVSQQYLGNLVECIRENDVSRALQIIDEMMSKGKDPVRFMEDFIYYYRDMLLYQTSPQLEHMLERVIVDDQFRKLSEE 320
Cdd:PRK05563 241 TGSVSQEALDDLVDAIVEGDVAKALKILEELLDEGKDPNRFIEDLIYYLRDLLLVKTSPELEILDESTENDELFKELSEK 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 321 MQPEVIYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQLCQQFMMQANGTDRLQAIMNRMQQLEKELEQVKKNGVPAGVQQE 400
Cdd:PRK05563 321 LDIERLYRMIDILNDAQQQIKWTNQPRIYLEVALVKLCEQAAASPEYDTELEVLLQRVEQLEQELKQLKAQPVGVAPEQK 400
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 401 vrETRATPKPVRTGSMKIPVGRVNEVLKQAKRQDLEQLKAVWGELLGRLKSYNKVAFAvLLENSEPVAASDDTYVLAFQY 480
Cdd:PRK05563 401 --EKKKEKKKNKKKKYKVPRGKIYKVLKEATRQDLELLKNVWGEILESLKAQRKSLRA-LLVNSEPVAASEDTVVLAFEY 477
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 481 EIHCKMASENREAMDTVEQALFELLSKRLNMIAIPKSEWGKIREDFLQREGGESEESPEKKEDPLIEEAVKLVGQELIEI 560
Cdd:PRK05563 478 EIHFEKAMLDKELNDTIENILSKLLGKSVEIVAVPEDEWQKIREEFLQKHKNEEEEEEEEEELPLIPEAKELFGEDLVEI 557

                 ..
gi 228822350 561 KE 562
Cdd:PRK05563 558 ID 559
dnaX_nterm TIGR02397
DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ ...
3-358 0e+00

DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ 365 amino acids of the translation of the dnaX gene. The full-length product of the dnaX gene in the model bacterium E. coli is the DNA polymerase III tau subunit. A translational frameshift leads to early termination and a truncated protein subunit gamma, about 1/3 shorter than tau and present in roughly equal amounts. This frameshift mechanism is not necessarily universal for species with DNA polymerase III but appears conserved in the exterme thermophile Thermus thermophilis. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274111 [Multi-domain]  Cd Length: 355  Bit Score: 553.33  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350    3 YQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCLGI 82
Cdd:TIGR02397   1 YQVLARKYRPQTFEDVIGQEHIVQTLKNAIKNGRIAHAYLFSGPRGTGKTSIARIFAKALNCQNGPDGEPCNECESCKEI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   83 TQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHKI 162
Cdd:TIGR02397  81 NSGSSLDVIEIDAASNNGVDDIREILDNVKYAPSSGKYKVYIIDEVHMLSKSAFNALLKTLEEPPEHVVFILATTEPHKI 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  163 PPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDEIVTTEDVLAVTG 242
Cdd:TIGR02397 161 PATILSRCQRFDFKRIPLEDIVERLKKILDKEGIKIEDEALELIARAADGSLRDALSLLDQLISFGNGKITYEDVNELLG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  243 SVSQQYLGNLVECIRENDVSRALQIIDEMMSKGKDPVRFMEDFIYYYRDMLLYQTSPqlEHMLERV-IVDDQFRKLSEEM 321
Cdd:TIGR02397 241 LVDDEKLIELLEAILNKDTAEALKILDEILESGVDPEKFLEDLIEILRDLLLIKKTP--SNLLAVLeSEQEFLKELALKL 318
                         330       340       350
                  ....*....|....*....|....*....|....*..
gi 228822350  322 QPEVIYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQLC 358
Cdd:TIGR02397 319 SLEFLLRLLDILLEALKDLRFSNDPRIWLEMTLLRLL 355
DnaX COG2812
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
1-359 2.71e-175

DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];


Pssm-ID: 442061 [Multi-domain]  Cd Length: 340  Bit Score: 498.56  E-value: 2.71e-175
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   1 MSYQAlyrtwrPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCL 80
Cdd:COG2812    1 MSYQV------PQTFDDVVGQEHVVRTLKNALASGRLAHAYLFTGPRGVGKTTLARILAKALNCENGPTGEPCGECESCR 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  81 GITQGSISDVLEIDA-ASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEP 159
Cdd:COG2812   75 AIAAGSHPDVIEIDAeASNIGVDDIRELIEKVSYAPVEGRYKVYIIDEAHMLTTEAFNALLKTLEEPPPHVVFILATTEP 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 160 HKIPPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYsdeivttedvla 239
Cdd:COG2812  155 QKLLPTILSRCQRFDFRRLPPEEIAEHLAKIAEREGIEIEPEALALIARAADGSMRDALSLLDQAIAF------------ 222
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 240 vtGSVS-QQYLGNLVECIRENDVSRALQIIDEMMSKGKDPVRFMEDFIYYYRDMLLYQTSPQLEHMLERVIVdDQFRKLS 318
Cdd:COG2812  223 --GLLDrRELLLDLLEALLAGDVAALLALAEELAKRGRDLKRFLDDLLSLLRDLLLLKLGPDAELLVNEDER-ERLQELA 299
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|.
gi 228822350 319 EEMQPEVIYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQLCQ 359
Cdd:COG2812  300 RRLSPERLLRAIQILLEARRELERNVNPRLALEMLLLRLAR 340
PRK14965 PRK14965
DNA polymerase III subunits gamma and tau; Provisional
1-562 4.13e-144

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237871 [Multi-domain]  Cd Length: 576  Bit Score: 428.01  E-value: 4.13e-144
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   1 MSYQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCL 80
Cdd:PRK14965   1 MSYLVLARKYRPQTFSDLTGQEHVSRTLQNAIDTGRVAHAFLFTGARGVGKTSTARILAKALNCEQGLTAEPCNVCPPCV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  81 GITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPH 160
Cdd:PRK14965  81 EITEGRSVDVFEIDGASNTGVDDIRELRENVKYLPSRSRYKIFIIDEVHMLSTNAFNALLKTLEEPPPHVKFIFATTEPH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 161 KIPPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDEIVTTEDVLAV 240
Cdd:PRK14965 161 KVPITILSRCQRFDFRRIPLQKIVDRLRYIADQEGISISDAALALVARKGDGSMRDSLSTLDQVLAFCGDAVGDDDVAEL 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 241 TGSVSQQYLGNLVECIRENDVSRALQIIDEMMSKGKDPVRFMEDFIYYYRDMLLYQTSPQLEHMLERVIVD-DQFRKLSE 319
Cdd:PRK14965 241 LGVVDRRLLLDISAAVFGRDTRALLEIVERVDEFGYNMRQFCQELIDHLRNLVVLRAVGEPGDLLDLSEAElAELRAQAA 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 320 EMQPEVIYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQLC--------QQFMmqangtDRLQAIMNRMqQLEKELEQVKKN 391
Cdd:PRK14965 321 AADAADLQRHLTLLLRAEGEMAHASFPRLVLEMALLKMAtlapgapvSELL------DRLEALERGA-PAPPSAAWGAPT 393
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 392 GVPAGVQQEVRETRATPKPVRTGSMKIPVGR--VNEVLKQAKRQDLEQLKAVWGELLGRLKSY---NKVAFAVLLENSEP 466
Cdd:PRK14965 394 PAAPAAPPPAAAPPVPPAAPARPAAARPAPApaPPAAAAPPARSADPAAAASAGDRWRAFVAFvkgKKPALGASLEQGSP 473
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 467 VAASDDTYVLAF---QYEIHCKMASENREAMDTVEQALF------ELLSKRLNMIAIPKSEWGKIREDFLQReggESEES 537
Cdd:PRK14965 474 LGVSAGLLEIGFpegSFELSAMQDPDSRAELKALAEQFFgrptrlRITVLAAPPGAAPPSLAEKKAAEREQR---QARLR 550
                        570       580
                 ....*....|....*....|....*
gi 228822350 538 PEKKEDPLIEEAVKLVGQELIEIKE 562
Cdd:PRK14965 551 EEAREHPLVQEALRVFGGEIDEVEE 575
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
1-562 8.37e-138

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 412.28  E-value: 8.37e-138
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   1 MSYQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEH-APVAEPCNECPSC 79
Cdd:PRK14950   1 MTVQVLYRKWRSQTFAELVGQEHVVQTLRNAIAEGRVAHAYLFTGPRGVGKTSTARILAKAVNCTTnDPKGRPCGTCEMC 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  80 LGITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEP 159
Cdd:PRK14950  81 RAIAEGSAVDVIEMDAASHTSVDDAREIIERVQFRPALARYKVYIIDEVHMLSTAAFNALLKTLEEPPPHAIFILATTEV 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 160 HKIPPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDEIVTTEDVLA 239
Cdd:PRK14950 161 HKVPATILSRCQRFDFHRHSVADMAAHLRKIAAAEGINLEPGALEAIARAATGSMRDAENLLQQLATTYGGEISLSQVQS 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 240 VTGSVSQQYLGNLVECIRENDVSRALQIIDEMMSKGKDPVRFMEDFIYYYRD-MLLYQTSpqlehmlERVIVD------D 312
Cdd:PRK14950 241 LLGISGDEEVKALAEALLAKDLKAALRTLNAVAADGADLRQFTRDLVEYLRQvMLLNSGA-------DRSLLDltadekA 313
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 313 QFRKLSEEMQPEVIYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQ-------LCQQFMMQANGTDRLQ-----------AI 374
Cdd:PRK14950 314 ALQKVSQIANLEALTKWVKAFSQLDFQLRTTSYGQLPLELAVIEallvpvpAPQPAKPTAAAPSPVRptpapstrpkaAA 393
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 375 MNRMQQLEKELEQVKKNGVPAG-VQQEVRETRATPKPVRTGSMKIPVGRVNEVLKQAKRQD---------LEQLKAVWGE 444
Cdd:PRK14950 394 AANIPPKEPVRETATPPPVPPRpVAPPVPHTPESAPKLTRAAIPVDEKPKYTPPAPPKEEEkaliadgdvLEQLEAIWKQ 473
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 445 LLGRLKSYNKVAFAVLLENSEPVAASDDTYVLAFQYEIHCKMASEnreamDTVEQALFELLSKRLN-MIAIPKSEwgkir 523
Cdd:PRK14950 474 ILRDVPPRSPAVQALLSSGVRPVSVEKNTLTLSFKSKFHKDKIEE-----PENRKITEELLSNFVGkTCAVRCTI----- 543
                        570       580       590
                 ....*....|....*....|....*....|....*....
gi 228822350 524 EDFLQREGGESEESPEKKEDPLIEEAVKLVGQELIEIKE 562
Cdd:PRK14950 544 EEKSEEPGDLREQIREARKDHLVKAAQNIFDAQIISVEE 582
PRK06305 PRK06305
DNA polymerase III subunits gamma and tau; Validated
2-357 4.56e-127

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 180523 [Multi-domain]  Cd Length: 451  Bit Score: 379.89  E-value: 4.56e-127
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   2 SYQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEH-APVAEPCNECPSCL 80
Cdd:PRK06305   3 SYQVSSRKYRPQTFSEILGQDAVVAVLKNALRFNRAAHAYLFSGIRGTGKTTLARIFAKALNCQNpTEDQEPCNQCASCK 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  81 GITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPH 160
Cdd:PRK06305  83 EISSGTSLDVLEIDGASHRGIEDIRQINETVLFTPSKSRYKIYIIDEVHMLTKEAFNSLLKTLEEPPQHVKFFLATTEIH 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 161 KIPPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDEIVTTEDVLAV 240
Cdd:PRK06305 163 KIPGTILSRCQKMHLKRIPEETIIDKLALIAKQEGIETSREALLPIARAAQGSLRDAESLYDYVVGLFPKSLDPDSVAKA 242
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 241 TGSVSQQYLGNLVECIRENDVSRALQIIDEMMSKGKDPVRFMEDFIYYYRDMLLYQTSPQLEhmlervivddqfrKLSEE 320
Cdd:PRK06305 243 LGLLSQDSLYTLDEAITTQNYAQALEPVTDAMNSGVAPAHFLHDLTLFFRNILLKQYNKQLS-------------SVATK 309
                        330       340       350
                 ....*....|....*....|....*....|....*..
gi 228822350 321 MQPEVIYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQL 357
Cdd:PRK06305 310 YSSEQLLEIIDFLGESAKHIQLTIFEKTFLETVIIHL 346
PRK14948 PRK14948
DNA polymerase III subunit gamma/tau;
1-449 1.31e-126

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237862 [Multi-domain]  Cd Length: 620  Bit Score: 384.31  E-value: 1.31e-126
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   1 MSYQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINC--EHAPVAEPCNECPS 78
Cdd:PRK14948   1 MAYEPLHHKYRPQRFDELVGQEAIATTLKNALISNRIAPAYLFTGPRGTGKTSSARILAKSLNClnSDKPTPEPCGKCEL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  79 CLGITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTE 158
Cdd:PRK14948  81 CRAIAAGNALDVIEIDAASNTGVDNIRELIERAQFAPVQARWKVYVIDECHMLSTAAFNALLKTLEEPPPRVVFVLATTD 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 159 PHKIPPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQaISYSDEIVTTEDVL 238
Cdd:PRK14948 161 PQRVLPTIISRCQRFDFRRIPLEAMVQHLSEIAEKESIEIEPEALTLVAQRSQGGLRDAESLLDQ-LSLLPGPITPEAVW 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 239 AVTGSVSQQYLGNLVECIRENDVSRALQIIDEMMSKGKDPVRFMEDFIYYYRDMLLYQTSPQlehMLERVIVDDQFR--- 315
Cdd:PRK14948 240 DLLGAVPEQDLLNLLKALASNDPESLLDSCRQLLDRGREPLAILQGLAAFYRDLLLAKTAPN---RPDLVAVSQQTWdel 316
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 316 -KLSEEMQPEVIYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQLCQQFMMQANGTD----RLQAIMNRMQQLEKELEQVKK 390
Cdd:PRK14948 317 cKLAKQINLERILQWQQHLKGSEYQLKNSTQPRLWLEVTLLGLLPSAFISEIANAsapaNPTPAPNPSPPPAPIQPSAPK 396
                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 228822350 391 NGVPAGVQQEVRETRATPKPVRTGSMKIPvgrVNEVLKQAKRQDLEQLKAVWGELLGRL 449
Cdd:PRK14948 397 TKQAATTPSPPPAKASPPIPVPAEPTEPS---PTPPANAANAPPSLNLEELWQQILAKL 452
PRK07133 PRK07133
DNA polymerase III subunits gamma and tau; Validated
1-358 1.91e-124

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235943 [Multi-domain]  Cd Length: 725  Bit Score: 382.24  E-value: 1.91e-124
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   1 MSYQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPV-AEPCNECPSC 79
Cdd:PRK07133   3 MKYKALYRKYRPKTFDDIVGQDHIVQTLKNIIKSNKISHAYLFSGPRGTGKTSVAKIFANALNCSHKTDlLEPCQECIEN 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  80 LgitQGSIsDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEP 159
Cdd:PRK07133  83 V---NNSL-DIIEMDAASNNGVDEIRELIENVKNLPTQSKYKIYIIDEVHMLSKSAFNALLKTLEEPPKHVIFILATTEV 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 160 HKIPPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDEIVTTEDVLA 239
Cdd:PRK07133 159 HKIPLTILSRVQRFNFRRISEDEIVSRLEFILEKENISYEKNALKLIAKLSSGSLRDALSIAEQVSIFGNNKITLKNVEE 238
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 240 VTGSVSQQYLGNLVECIRENDVSRALQIIDEMMSKGKDPVRFMEDFIYYYRDMLLYQ---TSPQLEHM----LERVIVDD 312
Cdd:PRK07133 239 LFGLVSNENLINLLNLLYSKDIKEVLNILNQIKEQGIDPELLLISLINLVKEFIIFNktkDNSLLEYYseedLEKLKIDD 318
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*.
gi 228822350 313 QFRklseemqpeviYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQLC 358
Cdd:PRK07133 319 DFA-----------YKFIEILFDLLKDLKISDNPNDTLEILIIKLL 353
PRK14969 PRK14969
DNA polymerase III subunits gamma and tau; Provisional
1-512 3.65e-120

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237873 [Multi-domain]  Cd Length: 527  Bit Score: 364.84  E-value: 3.65e-120
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   1 MSYQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCL 80
Cdd:PRK14969   1 MSYQVLARKWRPKSFSELVGQEHVVRALTNALEQQRLHHAYLFTGTRGVGKTTLARILAKSLNCETGVTATPCGVCSACL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  81 GITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPH 160
Cdd:PRK14969  81 EIDSGRFVDLIEVDAASNTQVDAMRELLDNAQYAPTRGRFKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPQ 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 161 KIPPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDEIVTTEDVLAV 240
Cdd:PRK14969 161 KIPVTVLSRCLQFNLKQMPPPLIVSHLQHILEQENIPFDATALQLLARAAAGSMRDALSLLDQAIAYGGGTVNESEVRAM 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 241 TGSVSQQYLGNLVECIRENDVSRALQIIDEMMSKGkdpVRF---MEDFIYYYRDMLLYQTSPQL--EHMLERvivdDQFR 315
Cdd:PRK14969 241 LGAIDQDYLFALLEALLAQDGAALLAIADAMEERS---LSFdaaLQDLAALLHRLAIAQTVPDSiaDDLPER----DRLL 313
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 316 KLSEEMQPEVI---YEI-IHtlskGQQEMKWTnhPRIFLEVVMVQLcqqfmmqangtdRLQAIMNRmqqlekelEQVKKN 391
Cdd:PRK14969 314 DLAKRLSPEDIqlyYQIaLH----GRRDLGLA--PDEYAGFTMTLL------------RMLAFRPS--------EQDSGA 367
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 392 GVPAGVQQEVRETRATPKPVRTGSmkipvgrvnevlKQAKRQDLEQLKAVWGELLGRLKsYNKVAFAvLLENSEPVAASD 471
Cdd:PRK14969 368 GRAPGAVPGVNRTRAVPTAAPAAP------------AAATPSDRQSFNGNWRALVDQLK-LSGLARE-LAQNCELKSFSE 433
                        490       500       510       520
                 ....*....|....*....|....*....|....*....|.
gi 228822350 472 DTYVLAFQyEIHCKMASENREamDTVEQALFELLSKRLNMI 512
Cdd:PRK14969 434 DRIELRVP-EAHKHLLDKPYQ--DKLQAALEQHFGRPVQLI 471
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
1-354 3.77e-120

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 368.42  E-value: 3.77e-120
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   1 MSYQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCL 80
Cdd:PRK07994   1 MSYQVLARKWRPQTFAEVVGQEHVLTALANALDLGRLHHAYLFSGTRGVGKTTIARLLAKGLNCETGITATPCGECDNCR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  81 GITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPH 160
Cdd:PRK07994  81 EIEQGRFVDLIEIDAASRTKVEDTRELLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 161 KIPPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDEIVTTEDVLAV 240
Cdd:PRK07994 161 KLPVTILSRCLQFHLKALDVEQIRQQLEHILQAEQIPFEPRALQLLARAADGSMRDALSLTDQAIASGNGQVTTDDVSAM 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 241 TGSVSQQYLGNLVECIRENDVSRALQIIDEMMSKGKdpvrfmeDFIYYYRDML-------LYQTSPQ--LEHMLERvivD 311
Cdd:PRK07994 241 LGTLDDDQALSLLEALVEGDGERVMALINQLAERGP-------DWEGLLVELLellhriaMAQLLPAalDNDMADI---E 310
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*.
gi 228822350 312 DQFRKLSEEMQPEVI---YEIihtLSKGQQEMKWTNHPRIFLEVVM 354
Cdd:PRK07994 311 LRLRELARTLPPEDVqlyYQT---LLIGRKDLPLAPDRRMGVEMTL 353
PRK14953 PRK14953
DNA polymerase III subunits gamma and tau; Provisional
1-349 5.88e-120

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237867 [Multi-domain]  Cd Length: 486  Bit Score: 362.99  E-value: 5.88e-120
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   1 MSYQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCL 80
Cdd:PRK14953   1 MMYIPFARKYRPKFFKEVIGQEIVVRILKNAVKLQRVSHAYIFAGPRGTGKTTIARILAKVLNCLNPQEGEPCGKCENCV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  81 GITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPH 160
Cdd:PRK14953  81 EIDKGSFPDLIEIDAASNRGIDDIRALRDAVSYTPIKGKYKVYIIDEAHMLTKEAFNALLKTLEEPPPRTIFILCTTEYD 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 161 KIPPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDEIVTTEDVLAV 240
Cdd:PRK14953 161 KIPPTILSRCQRFIFSKPTKEQIKEYLKRICNEEKIEYEEKALDLLAQASEGGMRDAASLLDQASTYGEGKVTIKVVEEF 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 241 TGSVSQQYLGNLVECIRENDVSRALQIIDEMMSKGKDPVRFMEDFIYYYRDMLLYQTspqLEHMLERVIVDDQFRKLSEE 320
Cdd:PRK14953 241 LGIVSQESVRKFLNLLLESDVDEAIKFLRTLEEKGYNLNKFWKQLEEEIRNILLNKS---LKNPEEVFQVEDFYRKLEKP 317
                        330       340
                 ....*....|....*....|....*....
gi 228822350 321 MqpEVIYEIIHTLSKGQQEMKWTNHPRIF 349
Cdd:PRK14953 318 L--EALLYLEDVINKAFSEARTRDPLRAY 344
PRK14962 PRK14962
DNA polymerase III subunits gamma and tau; Provisional
4-312 6.12e-117

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237869 [Multi-domain]  Cd Length: 472  Bit Score: 354.46  E-value: 6.12e-117
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   4 QALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCLGIT 83
Cdd:PRK14962   2 EALYRKYRPKTFSEVVGQDHVKKLIINALKKNSISHAYIFAGPRGTGKTTVARILAKSLNCENRKGVEPCNECRACRSID 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  84 QGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHKIP 163
Cdd:PRK14962  82 EGTFMDVIELDAASNRGIDEIRKIRDAVGYRPMEGKYKVYIIDEVHMLTKEAFNALLKTLEEPPSHVVFVLATTNLEKVP 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 164 PTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDEIVTTEDVLAVTGS 243
Cdd:PRK14962 162 PTIISRCQVIEFRNISDELIIKRLQEVAEAEGIEIDREALSFIAKRASGGLRDALTMLEQVWKFSEGKITLETVHEALGL 241
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 228822350 244 VSQQYLGNLVECIRENDVSRALQIIDEMMSKGKDPvrfmedfiyyyrDMLLYQTSPQLEHMLERVIVDD 312
Cdd:PRK14962 242 IPIEVVRDYINAIFNGDVKRVFTVLDDVYYSGKDY------------EVLIQQAIEDLVEDLERERAND 298
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
8-424 6.87e-116

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 356.78  E-value: 6.87e-116
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   8 RTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINC-EHAPVAEPCNECPSCLGITQGS 86
Cdd:PRK14971   9 RKYRPSTFESVVGQEALTTTLKNAIATNKLAHAYLFCGPRGVGKTTCARIFAKTINCqNLTADGEACNECESCVAFNEQR 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  87 ISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHKIPPTI 166
Cdd:PRK14971  89 SYNIHELDAASNNSVDDIRNLIEQVRIPPQIGKYKIYIIDEVHMLSQAAFNAFLKTLEEPPSYAIFILATTEKHKILPTI 168
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 167 ISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDEIVTTEDVLAVTGSVSQ 246
Cdd:PRK14971 169 LSRCQIFDFNRIQVADIVNHLQYVASKEGITAEPEALNVIAQKADGGMRDALSIFDQVVSFTGGNITYKSVIENLNILDY 248
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 247 QYLGNLVECIRENDVSRALQIIDEMMSKGKDPVRFMEDFIYYYRDMLLYQtSPQLEHMLE-RVIVDDQFRKLSEEMQPEV 325
Cdd:PRK14971 249 DYYFRLTDALLAGKVSDSLLLFDEILNKGFDGSHFITGLASHFRDLLVCK-DAATLQLLEvGESIRQRYLEQAQKCPMSF 327
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 326 IYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQLCQ--QFMMQANGTDRLQAIMNRM--QQLEKELEQVKKNGVPAGVQQEV 401
Cdd:PRK14971 328 LYRALKLCNQCDLNYRASKNKRLLVELTLIQLAQltQKGDDASGGRGPKQHIKPVftQPAAAPQPSAAAAASPSPSQSSA 407
                        410       420
                 ....*....|....*....|...
gi 228822350 402 RETRATPKPVRTGSMKIPVGRVN 424
Cdd:PRK14971 408 AAQPSAPQSATQPAGTPPTVSVD 430
PRK08691 PRK08691
DNA polymerase III subunits gamma and tau; Validated
1-275 4.84e-112

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236333 [Multi-domain]  Cd Length: 709  Bit Score: 349.39  E-value: 4.84e-112
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   1 MSYQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCL 80
Cdd:PRK08691   1 MAYQVLARKWRPKTFADLVGQEHVVKALQNALDEGRLHHAYLLTGTRGVGKTTIARILAKSLNCENAQHGEPCGVCQSCT 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  81 GITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPH 160
Cdd:PRK08691  81 QIDAGRYVDLLEIDAASNTGIDNIREVLENAQYAPTAGKYKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 161 KIPPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDEIVTTEDVLAV 240
Cdd:PRK08691 161 KVPVTVLSRCLQFVLRNMTAQQVADHLAHVLDSEKIAYEPPALQLLGRAAAGSMRDALSLLDQAIALGSGKVAENDVRQM 240
                        250       260       270
                 ....*....|....*....|....*....|....*
gi 228822350 241 TGSVSQQYLGNLVECIRENDVSRALQIIDEMMSKG 275
Cdd:PRK08691 241 IGAVDKQYLYELLTGIINQDGAALLAKAQEMAACA 275
PRK06647 PRK06647
DNA polymerase III subunits gamma and tau; Validated
1-426 1.35e-109

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235845 [Multi-domain]  Cd Length: 563  Bit Score: 338.67  E-value: 1.35e-109
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   1 MSYQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCL 80
Cdd:PRK06647   1 MSYRGTATKRRPRDFNSLEGQDFVVETLKHSIESNKIANAYIFSGPRGVGKTSSARAFARCLNCVNGPTPMPCGECSSCK 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  81 GITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPH 160
Cdd:PRK06647  81 SIDNDNSLDVIEIDGASNTSVQDVRQIKEEIMFPPASSRYRVYIIDEVHMLSNSAFNALLKTIEEPPPYIVFIFATTEVH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 161 KIPPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDEIVTTEDVLAV 240
Cdd:PRK06647 161 KLPATIKSRCQHFNFRLLSLEKIYNMLKKVCLEDQIKYEDEALKWIAYKSTGSVRDAYTLFDQVVSFSDSDITLEQIRSK 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 241 TGSVSQQYLGNLVECIRENDVSRALQIIDEMMSKGKDPVRFMEDFIYYYRDMLLYQTSPQLEHMLErvIVDDQFRKLSEE 320
Cdd:PRK06647 241 MGLTGDEFLEKLASSILNEDAKELLCVLDSVFLSGVSVEQFLLDCIEFFRELLFLKHGIKNEAFIG--IKAERLPEKLRE 318
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 321 MQPEVIYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQLCqqfmmqangtdRL------QAIMNRMQQLEKELEQVKKNGV- 393
Cdd:PRK06647 319 FDLSQIERAISVLLETYRDLQFSVNPRYELEINFSKIL-----------RLkdyvpnHELIKQIQDLESKLLEHAAPDSc 387
                        410       420       430
                 ....*....|....*....|....*....|....*
gi 228822350 394 --PAGVQQEVRETRAtPKPVRTgSMKIPVGRVNEV 426
Cdd:PRK06647 388 nfDVGSDNESTDDLS-PIPIDP-PLKAELPEIRSL 420
PRK14952 PRK14952
DNA polymerase III subunits gamma/tau;
4-505 5.64e-109

DNA polymerase III subunits gamma/tau;


Pssm-ID: 237866 [Multi-domain]  Cd Length: 584  Bit Score: 337.62  E-value: 5.64e-109
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   4 QALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCLGIT 83
Cdd:PRK14952   1 MALYRKYRPATFAEVVGQEHVTEPLSSALDAGRINHAYLFSGPRGCGKTSSARILARSLNCAQGPTATPCGVCESCVALA 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  84 Q---GSIsDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPH 160
Cdd:PRK14952  81 PngpGSI-DVVELDAASHGGVDDTRELRDRAFYAPAQSRYRIFIVDEAHMVTTAGFNALLKIVEEPPEHLIFIFATTEPE 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 161 KIPPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYS-DEIVTTEDVLA 239
Cdd:PRK14952 160 KVLPTIRSRTHHYPFRLLPPRTMRALIARICEQEGVVVDDAVYPLVIRAGGGSPRDTLSVLDQLLAGAaDTHVTYQRALG 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 240 VTGSVSQQYLGNLVECIRENDVSRALQIIDEMMSKGKDPVRFMEDFIYYYRDMLLYQTSPQlehMLERVIVD------DQ 313
Cdd:PRK14952 240 LLGATDVALIDDAVDALAADDAAALFGAIESVIDAGHDPRRFATDLLERFRDLIVLQAVPD---AAARGVVDapedvlER 316
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 314 FRKLSEEMQPEVIYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQLcqqfmMQANGTDRLQAIMNRMQQLEKELEQvkknGV 393
Cdd:PRK14952 317 MREQAARIGLATLTRYAEVVQAGLGEMRGATAPRLLLEVVCARL-----LLPSASDAESALLQRVERIETRLDM----SI 387
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 394 PAGVQQEVRETRATPKPVRTGSMKIPVGRVNEVLKQAKRQDLEQLKAV---WGELLGRLKSYNKVAfAVLLENSEPVAAS 470
Cdd:PRK14952 388 PANLLHNAPQAAPAPSAAAPEPKHQPAPEPRPVLAPTPASGEPNAAAVrsmWSTVRDKVRQRSRTT-EVMLAGATVRALE 466
                        490       500       510
                 ....*....|....*....|....*....|....*
gi 228822350 471 DDTYVLAFQYEIHCKMASENREAmDTVEQALFELL 505
Cdd:PRK14952 467 GNTLVLTHESAPLARRLSEQRNA-DVLAEALKDAL 500
PRK05896 PRK05896
DNA polymerase III subunits gamma and tau; Validated
1-296 1.49e-108

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235638 [Multi-domain]  Cd Length: 605  Bit Score: 337.20  E-value: 1.49e-108
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   1 MSYQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCL 80
Cdd:PRK05896   1 MSEITFYRKYRPHNFKQIIGQELIKKILVNAILNNKLTHAYIFSGPRGIGKTSIAKIFAKAINCLNPKDGDCCNSCSVCE 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  81 GITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPH 160
Cdd:PRK05896  81 SINTNQSVDIVELDAASNNGVDEIRNIIDNINYLPTTFKYKVYIIDEAHMLSTSAWNALLKTLEEPPKHVVFIFATTEFQ 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 161 KIPPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDEIVTTEDVLAV 240
Cdd:PRK05896 161 KIPLTIISRCQRYNFKKLNNSELQELLKSIAKKEKIKIEDNAIDKIADLADGSLRDGLSILDQLSTFKNSEIDIEDINKT 240
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 228822350 241 TGSVSQQYLGNLVECIRENDVSRALQIIDEMMSKGKDPVRFMEDFIYYYRDMLLYQ 296
Cdd:PRK05896 241 FGLVDNNKKINLIELIQKNDIEELRNLINELESKGINFEAFCRDLINLLIDLLVYQ 296
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
1-275 2.55e-108

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 339.54  E-value: 2.55e-108
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   1 MSYQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAP-----VAEPCNE 75
Cdd:PRK12323   1 MSYQVLARKWRPRDFTTLVGQEHVVRALTHALEQQRLHHAYLFTGTRGVGKTTLSRILAKSLNCTGADgeggiTAQPCGQ 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  76 CPSCLGITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILA 155
Cdd:PRK12323  81 CRACTEIDAGRFVDYIEMDAASNRGVDEMAQLLDKAVYAPTAGRFKVYMIDEVHMLTNHAFNAMLKTLEEPPEHVKFILA 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 156 TTEPHKIPPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDEIVTTE 235
Cdd:PRK12323 161 TTDPQKIPVTVLSRCLQFNLKQMPPGHIVSHLDAILGEEGIAHEVNALRLLAQAAQGSMRDALSLTDQAIAYSAGNVSEE 240
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 228822350 236 DVLAVTGSVSQQYLGNLVECIRENDVSRALQIIDEMMSKG 275
Cdd:PRK12323 241 AVRGMLGAIDQSYLVRLLDALAAEDGAALLAIADEMAGRS 280
PRK14954 PRK14954
DNA polymerase III subunits gamma and tau; Provisional
1-357 7.29e-106

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184918 [Multi-domain]  Cd Length: 620  Bit Score: 330.75  E-value: 7.29e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   1 MSYQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHA--------PVAEP 72
Cdd:PRK14954   1 MSYQVIARKYRPSKFADITAQEHITHTIQNSLRMDRVGHGYIFSGLRGVGKTTAARVFAKAVNCQRMiddpvylqEVTEP 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  73 CNECPSCLGITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIF 152
Cdd:PRK14954  81 CGECESCRDFDAGTSLNISEFDAASNNSVDDIRQLRENVRYGPQKGRYRVYIIDEVHMLSTAAFNAFLKTLEEPPPHAIF 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 153 ILATTEPHKIPPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYS---- 228
Cdd:PRK14954 161 IFATTELHKIPATIASRCQRFNFKRIPLDEIQSQLQMICRAEGIQIDADALQLIARKAQGSMRDAQSILDQVIAFSvgse 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 229 -DEIVTTEDVLAVTGSVSQQYLGNLVECIRENDVSRALQIIDEMMSKGKDPVRFMEDFIYYYRDMLLYQtSPQLEHMLER 307
Cdd:PRK14954 241 aEKVIAYQGVAELLNYIDDEQFFDVTDAIAENDAVKMLEVARFVIDNGYDEQDFLEKLIEHFRNFLVLY-NLRSTRLIER 319
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|.
gi 228822350 308 V-IVDDQFRKLSEEMQPEVIYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQL 357
Cdd:PRK14954 320 PeSVKERYQQSAGGLTPAAVMQMTDFLMKTQGELKFQFEYQFRFELALLRL 370
PRK09111 PRK09111
DNA polymerase III subunits gamma and tau; Validated
3-284 9.12e-106

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236382 [Multi-domain]  Cd Length: 598  Bit Score: 329.94  E-value: 9.12e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   3 YQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHA-----PVAEPCNECP 77
Cdd:PRK09111  11 YRVLARKYRPQTFDDLIGQEAMVRTLTNAFETGRIAQAFMLTGVRGVGKTTTARILARALNYEGPdgdggPTIDLCGVGE 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  78 SCLGITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATT 157
Cdd:PRK09111  91 HCQAIMEGRHVDVLEMDAASHTGVDDIREIIESVRYRPVSARYKVYIIDEVHMLSTAAFNALLKTLEEPPPHVKFIFATT 170
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 158 EPHKIPPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDEIVTTEDV 237
Cdd:PRK09111 171 EIRKVPVTVLSRCQRFDLRRIEADVLAAHLSRIAAKEGVEVEDEALALIARAAEGSVRDGLSLLDQAIAHGAGEVTAEAV 250
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 228822350 238 LAVTGSVSQQYLGNLVECIRENDVSRALQIIDEMMSKGKDPVRFMED 284
Cdd:PRK09111 251 RDMLGLADRARVIDLFEALMRGDVAAALAEFRAQYDAGADPVVVLTD 297
PRK14955 PRK14955
DNA polymerase III subunits gamma and tau; Provisional
1-357 1.51e-104

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184919 [Multi-domain]  Cd Length: 397  Bit Score: 320.30  E-value: 1.51e-104
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   1 MSYQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEH--------APVAEP 72
Cdd:PRK14955   1 MSYQVIARKYRPKKFADITAQEHITRTIQNSLRMGRVGHGYIFSGLRGVGKTTAARVFAKAVNCQRmiddadylQEVTEP 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  73 CNECPSCLGITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIF 152
Cdd:PRK14955  81 CGECESCRDFDAGTSLNISEFDAASNNSVDDIRLLRENVRYGPQKGRYRVYIIDEVHMLSIAAFNAFLKTLEEPPPHAIF 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 153 ILATTEPHKIPPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDE-- 230
Cdd:PRK14955 161 IFATTELHKIPATIASRCQRFNFKRIPLEEIQQQLQGICEAEGISVDADALQLIGRKAQGSMRDAQSILDQVIAFSVEse 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 231 ---IVTTEDVLAVTGSVSQQYLGNLVECIRENDVSRALQIIDEMMSKGKDPVRFMEDFIYYYRDMLLYQtSPQLEHMLER 307
Cdd:PRK14955 241 gegSIRYDKVAELLNYIDDEHFFAVTDAVADGDAVAMLDVAQFVIRNGYDEQDFLEKLIEHLRNFLVVH-NLRSTRLVER 319
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|.
gi 228822350 308 V-IVDDQFRKLSEEMQPEVIYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQL 357
Cdd:PRK14955 320 PdAVRERYERDAAKFSPEVIMQMTDLLLQTQKELKFQFEYQFRFELALLKL 370
PRK14956 PRK14956
DNA polymerase III subunits gamma and tau; Provisional
2-400 1.45e-102

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184920 [Multi-domain]  Cd Length: 484  Bit Score: 318.04  E-value: 1.45e-102
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   2 SYQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCLG 81
Cdd:PRK14956   4 THEVLSRKYRPQFFRDVIHQDLAIGALQNALKSGKIGHAYIFFGPRGVGKTTIARILAKRLNCENPIGNEPCNECTSCLE 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  82 ITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHK 161
Cdd:PRK14956  84 ITKGISSDVLEIDAASNRGIENIRELRDNVKFAPMGGKYKVYIIDEVHMLTDQSFNALLKTLEEPPAHIVFILATTEFHK 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 162 IPPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDEIVTTEDVLAVT 241
Cdd:PRK14956 164 IPETILSRCQDFIFKKVPLSVLQDYSEKLCKIENVQYDQEGLFWIAKKGDGSVRDMLSFMEQAIVFTDSKLTGVKIRKMI 243
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 242 GSVSQQYLGNLV-ECIRENDVSRALQIIDEMMSKGKDPVRFMEDFIYY------YRDMLLYQTSPQLEHMlERVIVDDQF 314
Cdd:PRK14956 244 GYHGIEFLTSFIkSLIDPDNHSKSLEILESLYQEGQDIYKFLWDSIEFthtlnlIRDSLADRESVNFPKE-DLQKMKSDF 322
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 315 RKLSEEMQPEV------IYEIIHTLS-KGQQEMKwtnhprIFLEVVMVQLCQQFMMQ--ANGTDRLQAIMNRMQ---QLE 382
Cdd:PRK14956 323 ENVDSSKLNFLsgklfeIYEKIKTIRlRNSFEIK------VFTEIQIKKLVEELTYPslAGLLDKINHLILMVQgskNIP 396
                        410
                 ....*....|....*...
gi 228822350 383 KELEQVKKNGVPAGVQQE 400
Cdd:PRK14956 397 EDVEPVKKISTPPPLQQE 414
PRK14963 PRK14963
DNA polymerase III subunits gamma and tau; Provisional
1-266 1.64e-102

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184927 [Multi-domain]  Cd Length: 504  Bit Score: 318.32  E-value: 1.64e-102
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   1 MSyqALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEhAPVAEPCNECPSCL 80
Cdd:PRK14963   1 MS--ALYQRARPITFDEVVGQEHVKEVLLAALRQGRLGHAYLFSGPRGVGKTTTARLIAMAVNCS-GEDPKPCGECESCL 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  81 GITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPH 160
Cdd:PRK14963  78 AVRRGAHPDVLEIDAASNNSVEDVRDLREKVLLAPLRGGRKVYILDEAHMMSKSAFNALLKTLEEPPEHVIFILATTEPE 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 161 KIPPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISySDEIVTTEDVLAV 240
Cdd:PRK14963 158 KMPPTILSRTQHFRFRRLTEEEIAGKLRRLLEAEGREAEPEALQLVARLADGAMRDAESLLERLLA-LGTPVTRKQVEEA 236
                        250       260
                 ....*....|....*....|....*.
gi 228822350 241 TGSVSQQYLGNLVECIRENDVSRALQ 266
Cdd:PRK14963 237 LGLPPQERLRGIAAALAQGDAAEALS 262
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
5-410 7.05e-101

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 323.48  E-value: 7.05e-101
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   5 ALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCLGITQ 84
Cdd:PRK07764   4 ALYRRYRPATFAEVIGQEHVTEPLSTALDSGRINHAYLFSGPRGCGKTSSARILARSLNCVEGPTSTPCGECDSCVALAP 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  85 ---GSIsDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHK 161
Cdd:PRK07764  84 ggpGSL-DVTEIDAASHGGVDDARELRERAFFAPAESRYKIFIIDEAHMVTPQGFNALLKIVEEPPEHLKFIFATTEPDK 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 162 IPPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYS-DEIVTTEDVLAV 240
Cdd:PRK07764 163 VIGTIRSRTHHYPFRLVPPEVMRGYLERICAQEGVPVEPGVLPLVIRAGGGSVRDSLSVLDQLLAGAgPEGVTYERAVAL 242
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 241 TGSVSQQYLGNLVECIRENDVSRALQIIDEMMSKGKDPVRFMEDFIYYYRDMLLYQTSPQlehMLERVIVD---DQFRKL 317
Cdd:PRK07764 243 LGVTDSALIDEAVDALAAGDGAALFGTVDRVIEAGHDPRRFAEDLLERLRDLIVLQAVPD---AAERGLVDapaDQLDRM 319
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 318 SEEMQ----PEVIY--EIIHTlskGQQEMKWTNHPRIFLEVvmvqLCQQFMMQANGTDRLqAIMNRMQQLEKELEQVKKN 391
Cdd:PRK07764 320 RAQAQrlgpAELTRaaDVVND---GLTEMRGATSPRLLLEL----LCARMLLPSASDDER-GLLARLERLERRLGVAGGA 391
                        410
                 ....*....|....*....
gi 228822350 392 GVPAGVQQEVRETRATPKP 410
Cdd:PRK07764 392 GAPAAAAPSAAAAAPAAAP 410
PRK14949 PRK14949
DNA polymerase III subunits gamma and tau; Provisional
1-278 2.32e-100

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237863 [Multi-domain]  Cd Length: 944  Bit Score: 324.76  E-value: 2.32e-100
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   1 MSYQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCL 80
Cdd:PRK14949   1 MSYQVLARKWRPATFEQMVGQSHVLHALTNALTQQRLHHAYLFTGTRGVGKTSLARLFAKGLNCEQGVTATPCGVCSSCV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  81 GITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPH 160
Cdd:PRK14949  81 EIAQGRFVDLIEVDAASRTKVDDTRELLDNVQYRPSRGRFKVYLIDEVHMLSRSSFNALLKTLEEPPEHVKFLLATTDPQ 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 161 KIPPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDEIVTTEDVLAV 240
Cdd:PRK14949 161 KLPVTVLSRCLQFNLKSLTQDEIGTQLNHILTQEQLPFEAEALTLLAKAANGSMRDALSLTDQAIAFGGGQVMLTQVQTM 240
                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 228822350 241 TGSVSQQYLGNLVECIRENDVSRALQIIDEMMSKGKDP 278
Cdd:PRK14949 241 LGSIDEQHVIALLKALTDADIGVLMQTCAQVLAFGADA 278
PRK08451 PRK08451
DNA polymerase III subunits gamma and tau; Validated
4-272 8.00e-100

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236267 [Multi-domain]  Cd Length: 535  Bit Score: 312.35  E-value: 8.00e-100
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   4 QALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCLGIT 83
Cdd:PRK08451   2 QALALKYRPKHFDELIGQESVSKTLSLALDNNRLAHAYLFSGLRGSGKTSSARIFARALVCEQGPSSTPCDTCIQCQSAL 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  84 QGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHKIP 163
Cdd:PRK08451  82 ENRHIDIIEMDAASNRGIDDIRELIEQTKYKPSMARFKIFIIDEVHMLTKEAFNALLKTLEEPPSYVKFILATTDPLKLP 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 164 PTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDEIVTTEDVLAVTGS 243
Cdd:PRK08451 162 ATILSRTQHFRFKQIPQNSIISHLKTILEKEGVSYEPEALEILARSGNGSLRDTLTLLDQAIIYCKNAITESKVADMLGL 241
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 228822350 244 VSQQYLGNLVECIRENDVSRALQ------------IIDEMM 272
Cdd:PRK08451 242 LDPSKLEDFFQAILNQDKEKLFEllkeledyeaemVLDEMM 282
PRK14961 PRK14961
DNA polymerase III subunits gamma and tau; Provisional
1-356 8.13e-99

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184925 [Multi-domain]  Cd Length: 363  Bit Score: 304.04  E-value: 8.13e-99
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   1 MSYQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCL 80
Cdd:PRK14961   1 MNYQILARKWRPQYFRDIIGQKHIVTAISNGLSLGRIHHAWLLSGTRGVGKTTIARLLAKSLNCQNGITSNPCRKCIICK 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  81 GITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPH 160
Cdd:PRK14961  81 EIEKGLCLDLIEIDAASRTKVEEMREILDNIYYSPSKSRFKVYLIDEVHMLSRHSFNALLKTLEEPPQHIKFILATTDVE 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 161 KIPPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDEIVTTEDVLAV 240
Cdd:PRK14961 161 KIPKTILSRCLQFKLKIISEEKIFNFLKYILIKESIDTDEYALKLIAYHAHGSMRDALNLLEHAINLGKGNINIKNVTDM 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 241 TGSVSQQYLGNLVECIRENDVSRALQIIDEMMSKGKDPVRFMEDFIYYYRDMLLYQTSPQLEHMLERVIVDDQFRKLSEE 320
Cdd:PRK14961 241 LGLLNEKQSFLLTDALLKKDSKKTMLLLNKISSIGIEWENILIEMLRFLHHISMSQSFPKIWNTIFIKNYKNQIQKIAQN 320
                        330       340       350
                 ....*....|....*....|....*....|....*.
gi 228822350 321 MQPEVIYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQ 356
Cdd:PRK14961 321 NKKTNIQLCYQILLNGRKELKFAPDQKIGVEMTLLR 356
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
1-300 2.49e-98

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 311.26  E-value: 2.49e-98
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   1 MSYQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAP-----VAEPCNE 75
Cdd:PRK14951   1 MSYLVLARKYRPRSFSEMVGQEHVVQALTNALTQQRLHHAYLFTGTRGVGKTTVSRILAKSLNCQGPDgqggiTATPCGV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  76 CPSCLGITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILA 155
Cdd:PRK14951  81 CQACRDIDSGRFVDYTELDAASNRGVDEVQQLLEQAVYKPVQGRFKVFMIDEVHMLTNTAFNAMLKTLEEPPEYLKFVLA 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 156 TTEPHKIPPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDEIVTTE 235
Cdd:PRK14951 161 TTDPQKVPVTVLSRCLQFNLRPMAPETVLEHLTQVLAAENVPAEPQALRLLARAARGSMRDALSLTDQAIAFGSGQLQEA 240
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 228822350 236 DVLAVTGSVSQQYLGNLVECIRENDVSRALQIIDEMMSKGKDPVRFMEDFIYYYRDMLLYQTSPQ 300
Cdd:PRK14951 241 AVRQMLGSVDRSHVFRLIDALAQGDGRTVVETADELRLNGLSAASTLEEMAAVLQRMAVLQAVPQ 305
PRK14970 PRK14970
DNA polymerase III subunits gamma and tau; Provisional
8-357 1.42e-97

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184934 [Multi-domain]  Cd Length: 367  Bit Score: 301.02  E-value: 1.42e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   8 RTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCehapvaepcnecPSCLGITQGSI 87
Cdd:PRK14970   9 RKYRPQTFDDVVGQSHITNTLLNAIENNHLAQALLFCGPRGVGKTTCARILARKINQ------------PGYDDPNEDFS 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  88 SDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHKIPPTII 167
Cdd:PRK14970  77 FNIFELDAASNNSVDDIRNLIDQVRIPPQTGKYKIYIIDEVHMLSSAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTIL 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 168 SRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDEIVTTEDVLAVTGSVSQQ 247
Cdd:PRK14970 157 SRCQIFDFKRITIKDIKEHLAGIAVKEGIKFEDDALHIIAQKADGALRDALSIFDRVVTFCGKNITRQAVTENLNILDYD 236
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 248 YLGNLVECIRENDVSRALQIIDEMMSKGKDPVRFMEDFIYYYRDMLLYQTsPQLEHMLErviVDDQFRKL-SEEMQPEVI 326
Cdd:PRK14970 237 TYINVTDLILENKIPELLLAFNEILRKGFDGHHFIAGLASHFRDLMVSKT-PATIALLE---VGEQAKKRyEVQSQKVSQ 312
                        330       340       350
                 ....*....|....*....|....*....|....
gi 228822350 327 YEIIHTLSKGQQ---EMKWTNHPRIFLEVVMVQL 357
Cdd:PRK14970 313 SFLLSGIDIANDcdlKYKLSKNQRLLVELALMQL 346
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
1-271 3.79e-97

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 313.71  E-value: 3.79e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   1 MSYQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCL 80
Cdd:PRK07003   1 MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  81 GITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPH 160
Cdd:PRK07003  81 EIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQ 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 161 KIPPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDEIVTTEDVLAV 240
Cdd:PRK07003 161 KIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEERIAFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTETAVSGM 240
                        250       260       270
                 ....*....|....*....|....*....|.
gi 228822350 241 TGSVSQQYLGNLVECIRENDVSRALQIIDEM 271
Cdd:PRK07003 241 LGALDQTYMVRLLDALAAGDGPEILAVADEM 271
PRK14964 PRK14964
DNA polymerase III subunits gamma and tau; Provisional
10-358 8.64e-97

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237870 [Multi-domain]  Cd Length: 491  Bit Score: 303.24  E-value: 8.64e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  10 WRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCLGITQGSISD 89
Cdd:PRK14964   7 YRPSSFKDLVGQDVLVRILRNAFTLNKIPQSILLVGASGVGKTTCARIISLCLNCSNGPTSDPCGTCHNCISIKNSNHPD 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  90 VLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHKIPPTIISR 169
Cdd:PRK14964  87 VIEIDAASNTSVDDIKVILENSCYLPISSKFKVYIIDEVHMLSNSAFNALLKTLEEPAPHVKFILATTEVKKIPVTIISR 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 170 CQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDEIVTTEDVLAVTGSVSQQYL 249
Cdd:PRK14964 167 CQRFDLQKIPTDKLVEHLVDIAKKENIEHDEESLKLIAENSSGSMRNALFLLEQAAIYSNNKISEKSVRDLLGCVDKHIL 246
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 250 GNLVECIRENDVSRALQIIDEMMSKGkDPVRFMEDFIYYYRDMLLYQTSPQLEHMLERVIVDDQfrKLSEEMQPEVIYEI 329
Cdd:PRK14964 247 EDLVEAILLGDAQSALNVFRELCNTS-NPVIILEGMLQIIYEICYFSITKEIDFLLGEDLITRI--KSLKIGSTIFLSRL 323
                        330       340
                 ....*....|....*....|....*....
gi 228822350 330 IHTLSKGQQEMKWTNHPRIFLEVVMVQLC 358
Cdd:PRK14964 324 WQMLLKGIQEVKSSTCVKQAAEMMIIRLC 352
PRK14959 PRK14959
DNA polymerase III subunits gamma and tau; Provisional
1-357 2.77e-94

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184923 [Multi-domain]  Cd Length: 624  Bit Score: 300.83  E-value: 2.77e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   1 MSYQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCL 80
Cdd:PRK14959   1 MSHASLTARYRPQTFAEVAGQETVKAILSRAAQENRVAPAYLFSGTRGVGKTTIARIFAKALNCETAPTGEPCNTCEQCR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  81 GITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPH 160
Cdd:PRK14959  81 KVTQGMHVDVVEIDGASNRGIDDAKRLKEAIGYAPMEGRYKVFIIDEAHMLTREAFNALLKTLEEPPARVTFVLATTEPH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 161 KIPPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDEIVTTEDVLAV 240
Cdd:PRK14959 161 KFPVTIVSRCQHFTFTRLSEAGLEAHLTKVLGREGVDYDPAAVRLIARRAAGSVRDSMSLLGQVLALGESRLTIDGARGV 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 241 TGSVSQQYLGNLVECIRENDVSRALQIIDEMMSKGKDPVRFMEDFIYYYRDMLLYQTS-----PQLEHMLERVivdDQFR 315
Cdd:PRK14959 241 LGLAGQELFLRLMEALAAQDCLGVANVVRELLDRGVDMGFFLRELVATWRNLFMLRQAgeaalASLDLPEDEA---RQWL 317
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|..
gi 228822350 316 KLSEEMQPEVIYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQL 357
Cdd:PRK14959 318 GWAKRFEPAHIHACWQMTLEGQRRVLTSLEPAMALELLLLNL 359
PRK14957 PRK14957
DNA polymerase III subunits gamma and tau; Provisional
1-476 3.79e-89

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184921 [Multi-domain]  Cd Length: 546  Bit Score: 285.05  E-value: 3.79e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   1 MSYQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCL 80
Cdd:PRK14957   1 MSYQALARKYRPQSFAEVAGQQHALNSLVHALETQKVHHAYLFTGTRGVGKTTLGRLLAKCLNCKTGVTAEPCNKCENCV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  81 GITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPH 160
Cdd:PRK14957  81 AINNNSFIDLIEIDAASRTGVEETKEILDNIQYMPSQGRYKVYLIDEVHMLSKQSFNALLKTLEEPPEYVKFILATTDYH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 161 KIPPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDEIVTTEDVLAV 240
Cdd:PRK14957 161 KIPVTILSRCIQLHLKHISQADIKDQLKIILAKENINSDEQSLEYIAYHAKGSLRDALSLLDQAISFCGGELKQAQIKQM 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 241 TGSVSQQYLGNLVECIRENDVSRALQIIDEMMSKGKDPVRFMEDFIYYYRDMLLYQTSPQLEHM--LERVIVDDQFRKLS 318
Cdd:PRK14957 241 LGIIDSEEVYSIINAIIDNDPKAILPAIKNLALTESSADAVLDRIAEIWFACCIYSFTQSLDAVndIDVDIINNILAKIS 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 319 EEmQPEVIYEIIHTLSKgqqemKWTNHPRIFLEVVMVQLcqqfmmqangtdRLQAIMNRmqQLEKELEQVKKNGVPAGVQ 398
Cdd:PRK14957 321 IE-QAHFLYQLTITAKK-----DIALAPNFETGVTMAIL------------RLIAFQKK--NLIDKTQTSKSNISPIVSK 380
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 399 QEVRETRATPKPVRTGSMKIPVGRVNEVLKQAKRQDLEQLKAVWGELLGR--LKSYNK-VAFavlleNSEPVAASDDTYV 475
Cdd:PRK14957 381 NDINLLKNTFKSEQPKQTVKAVVAQNNDSTASENTQEQSLDKKWFNLLNRikLKGFTKtLAF-----NSHLISDNSETFV 455

                 .
gi 228822350 476 L 476
Cdd:PRK14957 456 I 456
PRK14960 PRK14960
DNA polymerase III subunit gamma/tau;
3-467 3.65e-86

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237868 [Multi-domain]  Cd Length: 702  Bit Score: 281.55  E-value: 3.65e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   3 YQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCLGI 82
Cdd:PRK14960   2 YQVLARKYRPRNFNELVGQNHVSRALSSALERGRLHHAYLFTGTRGVGKTTIARILAKCLNCETGVTSTPCEVCATCKAV 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  83 TQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHKI 162
Cdd:PRK14960  82 NEGRFIDLIEIDAASRTKVEDTRELLDNVPYAPTQGRFKVYLIDEVHMLSTHSFNALLKTLEEPPEHVKFLFATTDPQKL 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 163 PPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDEIVTTEDVLAVTG 242
Cdd:PRK14960 162 PITVISRCLQFTLRPLAVDEITKHLGAILEKEQIAADQDAIWQIAESAQGSLRDALSLTDQAIAYGQGAVHHQDVKEMLG 241
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 243 SVSQQYLGNLVECIRENDVSRALQIIDEMMSKGKDPVRFMEDFIYYYRDMLLYQTSPQL-----EHMLERVIvddQFRKL 317
Cdd:PRK14960 242 LIDRTIIYDLILAVHQNQREKVSQLLLQFRYQALDVSLVLDQLISTLHELALLQYLPELglkysEEINAKIL---QLSKL 318
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 318 SEEMQPEVIYEIIhtlSKGQQEMKWTNHPRIFLEVVMVQLC-------QQFMMQANGTDRLQAIMNRMQQLEKELEQVKK 390
Cdd:PRK14960 319 ISAQDLQLYYQIA---CKGRSDLQLAVTQEQGFEMCVLRLLafrplapNEILVSEPVQQNGQAEVGLNSQAQTAQEITPV 395
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 391 NGV--------PAGVQQEVR-ETRATPKPVRTGSMKiPVGRVNEVLKQAKRQDLEQLKAVWGELLGRLKSYNKVAFAVLL 461
Cdd:PRK14960 396 SAVqpvevisqPAMVEPEPEpEPEPEPEPEPEPEPE-PEPEPEPEPEPQPNQDLMVFDPNHHELIGLESAVVQETVSVLE 474

                 ....*.
gi 228822350 462 ENSEPV 467
Cdd:PRK14960 475 EDFIPV 480
PRK14958 PRK14958
DNA polymerase III subunits gamma and tau; Provisional
1-367 3.82e-83

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184922 [Multi-domain]  Cd Length: 509  Bit Score: 268.52  E-value: 3.82e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   1 MSYQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCL 80
Cdd:PRK14958   1 MAHQVLARKWRPRCFQEVIGQAPVVRALSNALDQQYLHHAYLFTGTRGVGKTTISRILAKCLNCEKGVSANPCNDCENCR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  81 GITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPH 160
Cdd:PRK14958  81 EIDEGRFPDLFEVDAASRTKVEDTRELLDNIPYAPTKGRFKVYLIDEVHMLSGHSFNALLKTLEEPPSHVKFILATTDHH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 161 KIPPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDEIVTTEDVLAV 240
Cdd:PRK14958 161 KLPVTVLSRCLQFHLAQLPPLQIAAHCQHLLKEENVEFENAALDLLARAANGSVRDALSLLDQSIAYGNGKVLIADVKTM 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 241 TGSVSQQYLGNLVECIRENDVSRALQIIDEMMSKGKDPVRFMEDFIYYYRDMLLYQTSPqlEHMLERviVDDQFRKLSEE 320
Cdd:PRK14958 241 LGTIEPLLLFDILEALAAKAGDRLLGCVTRLVEQGVDFSNALADLLSLLHQIAIIQTVP--EALIEN--DSEQLRQLAKL 316
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*..
gi 228822350 321 MQPEVIYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQLCQQFMMQANG 367
Cdd:PRK14958 317 LDREDVQLFYQIGLIGQRDLAYSPTPQTGFEMTLLRMLAFYPSAANA 363
PRK06645 PRK06645
DNA polymerase III subunits gamma and tau; Validated
3-356 1.32e-82

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 180643 [Multi-domain]  Cd Length: 507  Bit Score: 266.72  E-value: 1.32e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   3 YQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEhAPVAE-----PCNECP 77
Cdd:PRK06645   8 YIPFARKYRPSNFAELQGQEVLVKVLSYTILNDRLAGGYLLTGIRGVGKTTSARIIAKAVNCS-ALITEnttikTCEQCT 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  78 SCLGITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATT 157
Cdd:PRK06645  87 NCISFNNHNHPDIIEIDAASKTSVDDIRRIIESAEYKPLQGKHKIFIIDEVHMLSKGAFNALLKTLEEPPPHIIFIFATT 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 158 EPHKIPPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYS---DEIVTT 234
Cdd:PRK06645 167 EVQKIPATIISRCQRYDLRRLSFEEIFKLLEYITKQENLKTDIEALRIIAYKSEGSARDAVSILDQAASMSaksDNIISP 246
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 235 EDVLAVTGSVSQQYLGNLVECIRENDVSRALQIIDEMMSKGKDPVRFME---DFIYYYR--DMLLYQTSPQLEHMlervi 309
Cdd:PRK06645 247 QVINQMLGLVDSSVIIEFVEYIIHRETEKAINLINKLYGSSVNLEIFIEsvsDFIAYLNkvKMLPNYSLPIYESF----- 321
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*..
gi 228822350 310 vDDQFRKLSEEMQPEVIYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQ 356
Cdd:PRK06645 322 -NDRTKSILDKISLPHLSILWQIYNKGVGEIKISYNQLTETEMLVIK 367
HolB COG0470
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
21-307 2.23e-59

DNA polymerase III, delta prime subunit [Replication, recombination and repair];


Pssm-ID: 440238 [Multi-domain]  Cd Length: 289  Bit Score: 199.05  E-value: 2.23e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  21 QKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCLgITQGSISDVLEIDAASNN- 99
Cdd:COG0470    1 QEEAWEQLLAAAESGRLPHALLLHGPPGIGKTTLALALARDLLCENPEGGKACGQCHSRL-MAAGNHPDLLELNPEEKSd 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 100 --GVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHKIPPTIISRCQRFEFRK 177
Cdd:COG0470   80 qiGIDQIRELGEFLSLTPLEGGRKVVIIDEADAMNEAAANALLKTLEEPPKNTPFILIANDPSRLLPTIRSRCQVIRFRP 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 178 ISVNDIVERLSTvvtnEGtqVEDEALQIVARAAEGGMRDALSLIdQAISYSDEIVttEDVLAVTGSVSQQYLgnLVECIR 257
Cdd:COG0470  160 PSEEEALAWLRE----EG--VDEDALEAILRLAGGDPRAAINLL-QALAGRKELL--EDLAALLSRDRALEL--LDALLK 228
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 228822350 258 ENDVSR----ALQIIDEMMSKGKDPVRF-MEDFIYYYRDMLLYQTSP--QLEHMLER 307
Cdd:COG0470  229 AEALELldwlLKWLLDNLPLEYAGEDLArAYEALSEADRRLGRYANDrlLLEALLAK 285
holB TIGR00678
DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' ...
26-212 3.73e-58

DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' subunit of DNA polymerase III. Delta' is homologous to the gamma and tau subunits, which form an outgroup for phylogenetic comparison. The gamma/tau branch of the tree is much more tighly conserved than the delta' branch, and some members of that branch score more highly against this model than some proteins classisified as delta'. The noise cutoff is set to detect weakly scoring delta' subunits rather than to exclude gamma/tau subunits. At position 126-127 of the seed alignment, this family lacks the HM motif of gamma/tau; at 132 it has a near-invariant A vs. an invariant F in gamma/tau. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273213 [Multi-domain]  Cd Length: 188  Bit Score: 192.07  E-value: 3.73e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   26 KTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCLGITQGSISDVLEIDAASNN-GVDEI 104
Cdd:TIGR00678   2 QQLKRALEKGRLAHAYLFTGPEGVGKELLALALAKALLCEQRGGGEPCGECHSCRLIEAGNHPDLHRLEPEGQSiKVDQV 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  105 RDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHKIPPTIISRCQRFEFRKISVNDIV 184
Cdd:TIGR00678  82 RELVEFLSRTPQESGRRVVIIEDAERMNEAAANALLKTLEEPPPNTLFILITPSPEKLLPTIRSRCQRLPFPPLSEEALL 161
                         170       180
                  ....*....|....*....|....*...
gi 228822350  185 ERLstvvtnEGTQVEDEALQIVARAAEG 212
Cdd:TIGR00678 162 QWL------IRQGISEEAAELLLALAGG 183
DNA_pol3_delta2 pfam13177
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ...
20-179 6.49e-55

DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.


Pssm-ID: 433013 [Multi-domain]  Cd Length: 161  Bit Score: 182.80  E-value: 6.49e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   20 GQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCLGITQGSISDVLEIDAASNN 99
Cdd:pfam13177   1 GQPEAIQLLQNSLENGRLSHAYLFSGPEGVGKLELALAFAKALFCEEPGDDLPCGQCRSCRRIESGNHPDLVIIEPEGQS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  100 -GVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHKIPPTIISRCQRFEFRKI 178
Cdd:pfam13177  81 iKIDQIRELQKEFSKSPYEGKKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRCQIIRFKPL 160

                  .
gi 228822350  179 S 179
Cdd:pfam13177 161 S 161
PRK08058 PRK08058
DNA polymerase III subunit delta'; Validated
21-323 1.08e-38

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181214 [Multi-domain]  Cd Length: 329  Bit Score: 144.68  E-value: 1.08e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  21 QKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCLGITQGSISDVLEI--DAASN 98
Cdd:PRK08058  11 QPVVVKMLQNSIAKNRLSHAYLFEGAKGTGKKATALWLAKSLFCLERNGVEPCGTCTNCKRIDSGNHPDVHLVapDGQSI 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  99 NgVDEIRDIrdKVKYAPSAVE--YKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHKIPPTIISRCQRFEFR 176
Cdd:PRK08058  91 K-KDQIRYL--KEEFSKSGVEsnKKVYIIEHADKMTASAANSLLKFLEEPSGGTTAILLTENKHQILPTILSRCQVVEFR 167
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 177 KISVNDIVERLstvvTNEGTQvedEALQIVARAAEGGMRDALSLIDqaisySDEIVTtedvlavtgsvSQQYLGNLVECI 256
Cdd:PRK08058 168 PLPPESLIQRL----QEEGIS---ESLATLLAGLTNSVEEALALSE-----DDWFAQ-----------ARALVIKLYEAL 224
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 257 RENDVSRALQIIDEMMS--KGKDPVRFMEDFI-YYYRDMLLYQTSPQlehmlERVIVDDQFRKLSEEMQP 323
Cdd:PRK08058 225 HEKDLQSFVFVQEKWMPlfKEKDQQQLGLDLLlLIYRDLLYLQLGEE-----DRLVFREQKEMLQQLALS 289
PRK07940 PRK07940
DNA polymerase III subunit delta'; Validated
15-212 4.42e-34

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236134 [Multi-domain]  Cd Length: 394  Bit Score: 133.50  E-value: 4.42e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  15 FEDVVGQKHVTKTLQNA---------LLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHaPVAEPCNECPSCLGITQG 85
Cdd:PRK07940   4 WDDLVGQEAVVAELRAAaraaradvaAAGSGMTHAWLFTGPPGSGRSVAARAFAAALQCTD-PDEPGCGECRACRTVLAG 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  86 SISDVLEIDA-ASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHKIPP 164
Cdd:PRK07940  83 THPDVRVVAPeGLSIGVDEVRELVTIAARRPSTGRWRIVVIEDADRLTERAANALLKAVEEPPPRTVWLLCAPSPEDVLP 162
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 228822350 165 TIISRCQRFEFRKISVNDIVERLstvVTNEGtqVEDEALQIVARAAEG 212
Cdd:PRK07940 163 TIRSRCRHVALRTPSVEAVAEVL---VRRDG--VDPETARRAARASQG 205
rfc PRK00440
replication factor C small subunit; Reviewed
10-315 5.86e-34

replication factor C small subunit; Reviewed


Pssm-ID: 234763 [Multi-domain]  Cd Length: 319  Bit Score: 131.15  E-value: 5.86e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  10 WRPQKFEDVVGQKHVTKTLQNALLQEKVSHaYLFSGPRGTGKTTIAKVFAKAIncehapVAEPCNEcpsclgitqgsisD 89
Cdd:PRK00440  11 YRPRTLDEIVGQEEIVERLKSYVKEKNMPH-LLFAGPPGTGKTTAALALAREL------YGEDWRE-------------N 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  90 VLEIDAASNNGVDEIRD-IRDKVKYAPSA-VEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHKIPPTII 167
Cdd:PRK00440  71 FLELNASDERGIDVIRNkIKEFARTAPVGgAPFKIIFLDEADNLTSDAQQALRRTMEMYSQNTRFILSCNYSSKIIDPIQ 150
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 168 SRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIdQAISYSDEIVTTEDVLAVTGSVSQQ 247
Cdd:PRK00440 151 SRCAVFRFSPLKKEAVAERLRYIAENEGIEITDDALEAIYYVSEGDMRKAINAL-QAAAATGKEVTEEAVYKITGTARPE 229
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 228822350 248 YLGNLVECIRENDVSRALQIIDEMMSK----GKDPVRFMedfiyyYRDMLLYQTSPQLEHMLERVIVDDQFR 315
Cdd:PRK00440 230 EIREMIELALNGDFTEAREKLRDLMIDyglsGEDIIKQI------HREVWSLDIPEELKVELIDAIGEADFR 295
PRK13342 PRK13342
recombination factor protein RarA; Reviewed
11-248 8.69e-34

recombination factor protein RarA; Reviewed


Pssm-ID: 237355 [Multi-domain]  Cd Length: 413  Bit Score: 132.90  E-value: 8.69e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  11 RPQKFEDVVGQKHVT---KTLQNALLQEKVSHAyLFSGPRGTGKTTIAKVFAKAINCEhapvaepcnecpsclgitqgsi 87
Cdd:PRK13342   7 RPKTLDEVVGQEHLLgpgKPLRRMIEAGRLSSM-ILWGPPGTGKTTLARIIAGATDAP---------------------- 63
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  88 sdVLEIDAAsNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHmlsmgAFN-----ALLKTLEEppGHVIFILATTE-P-H 160
Cdd:PRK13342  64 --FEALSAV-TSGVKDLREVIEEARQRRSAGRRTILFIDEIH-----RFNkaqqdALLPHVED--GTITLIGATTEnPsF 133
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 161 KIPPTIISRCQRFEFRKISVNDIVERLSTVVTNEG---TQVEDEALQIVARAAEGGMRDALSLIDQAiSYSDEIVTTEDV 237
Cdd:PRK13342 134 EVNPALLSRAQVFELKPLSEEDIEQLLKRALEDKErglVELDDEALDALARLANGDARRALNLLELA-ALGVDSITLELL 212
                        250
                 ....*....|.
gi 228822350 238 LAVTGSVSQQY 248
Cdd:PRK13342 213 EEALQKRAARY 223
PRK12402 PRK12402
replication factor C small subunit 2; Reviewed
9-272 1.10e-30

replication factor C small subunit 2; Reviewed


Pssm-ID: 237090 [Multi-domain]  Cd Length: 337  Bit Score: 122.41  E-value: 1.10e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   9 TWRPQKFEDVVGQKHVTKTLQnALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPvaepcnecpsclgitqgsiS 88
Cdd:PRK12402   8 KYRPALLEDILGQDEVVERLS-RAVDSPNLPHLLVQGPPGSGKTAAVRALARELYGDPWE-------------------N 67
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  89 DVLEIDAAS--NNGVDEIRD-----------------IRDKVK--------YAPSAVEYKVYIIDEVHMLSMGAFNALLK 141
Cdd:PRK12402  68 NFTEFNVADffDQGKKYLVEdprfahflgtdkrirssKIDNFKhvlkeyasYRPLSADYKTILLDNAEALREDAQQALRR 147
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 142 TLEEPPGHVIFILATTEPHKIPPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLI 221
Cdd:PRK12402 148 IMEQYSRTCRFIIATRQPSKLIPPIRSRCLPLFFRAPTDDELVDVLESIAEAEGVDYDDDGLELIAYYAGGDLRKAILTL 227
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|..
gi 228822350 222 DQAISYSDEIvTTEDVLAVTGSV-SQQYLGNLVECIRENDVSRALQIIDEMM 272
Cdd:PRK12402 228 QTAALAAGEI-TMEAAYEALGDVgTDEVIESLLDAAEAGDFTDARKTLDDLL 278
PRK07399 PRK07399
DNA polymerase III subunit delta'; Validated
14-183 5.38e-29

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236011 [Multi-domain]  Cd Length: 314  Bit Score: 116.92  E-value: 5.38e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  14 KFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHapvaePCNECPSCLgITQGSISDVL-- 91
Cdd:PRK07399   2 LFANLIGQPLAIELLTAAIKQNRIAPAYLFAGPEGVGRKLAALCFIEGLLSQG-----SPSKNIRRR-LEEGNHPDLLwv 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  92 ----------------EIDAASNNGVDEIR--DIRD-KVKYAPSAVE--YKVYIIDEVHMLSMGAFNALLKTLEEpPGHV 150
Cdd:PRK07399  76 eptyqhqgklitaseaEEAGLKRKAPPQIRleQIREiKRFLSRPPLEapRKVVVIEDAETMNEAAANALLKTLEE-PGNG 154
                        170       180       190
                 ....*....|....*....|....*....|...
gi 228822350 151 IFILATTEPHKIPPTIISRCQRFEFRKISVNDI 183
Cdd:PRK07399 155 TLILIAPSPESLLPTIVSRCQIIPFYRLSDEQL 187
PRK05707 PRK05707
DNA polymerase III subunit delta'; Validated
39-223 5.36e-28

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180215 [Multi-domain]  Cd Length: 328  Bit Score: 114.41  E-value: 5.36e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  39 HAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCLGITQGSISD--VLEIDAASNN-GVDEIRDIRDKVKYAP 115
Cdd:PRK05707  23 HAYLLHGPAGIGKRALAERLAAALLCEAPQGGGACGSCKGCQLLRAGSHPDnfVLEPEEADKTiKVDQVRELVSFVVQTA 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 116 SAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHKIPPTIISRCQRFEFRKISVNDIVERLSTVVTNEG 195
Cdd:PRK05707 103 QLGGRKVVLIEPAEAMNRNAANALLKSLEEPSGDTVLLLISHQPSRLLPTIKSRCQQQACPLPSNEESLQWLQQALPESD 182
                        170       180
                 ....*....|....*....|....*...
gi 228822350 196 tqvEDEALQIVARAAEGGMRdALSLIDQ 223
Cdd:PRK05707 183 ---ERERIELLTLAGGSPLR-ALQLHEQ 206
RarA COG2256
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, ...
11-242 1.57e-25

Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, recombination and repair];


Pssm-ID: 441857 [Multi-domain]  Cd Length: 439  Bit Score: 109.38  E-value: 1.57e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  11 RPQKFEDVVGQKHVT---KTLQNALLQEKVsHAYLFSGPRGTGKTTIAKVFAKAINCEHAPvaepcnecpsclgitqgsI 87
Cdd:COG2256   20 RPRTLDEVVGQEHLLgpgKPLRRAIEAGRL-SSMILWGPPGTGKTTLARLIANATDAEFVA------------------L 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  88 SdvleidaASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHmlsmgAFN-----ALLKTLEEppGHVIFILATTE-P-H 160
Cdd:COG2256   81 S-------AVTSGVKDIREVIEEARERRAYGRRTILFVDEIH-----RFNkaqqdALLPHVED--GTITLIGATTEnPsF 146
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 161 KIPPTIISRCQRFEFRKISVNDIVERLSTVVTNEGT-------QVEDEALQIVARAAEGGMRDALSLIDQAISYSDE--- 230
Cdd:COG2256  147 EVNSALLSRCRVFVLKPLSEEDLEQLLERALADDERglggyklELDDEALEALARLADGDARRALNALELAVLSAPPdgv 226
                        250
                 ....*....|...
gi 228822350 231 -IVTTEDVLAVTG 242
Cdd:COG2256  227 iEITLELVEEALQ 239
PRK09112 PRK09112
DNA polymerase III subunit delta'; Validated
18-238 1.88e-25

DNA polymerase III subunit delta'; Validated


Pssm-ID: 169667 [Multi-domain]  Cd Length: 351  Bit Score: 107.82  E-value: 1.88e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  18 VVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAI----NCEHAP--VAEPCNECPSCLGITQGSISDVL 91
Cdd:PRK09112  25 LFGHEEAEAFLAQAYREGKLHHALLFEGPEGIGKATLAFHLANHIlshpDPAEAPetLADPDPASPVWRQIAQGAHPNLL 104
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  92 EID---------AASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHKI 162
Cdd:PRK09112 105 HITrpfdektgkFKTAITVDEIRRVGHFLSQTSGDGNWRIVIIDPADDMNRNAANAILKTLEEPPARALFILISHSSGRL 184
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 228822350 163 PPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTqvEDEALQIVARAAEGGMRDALSLidqaISYSD-EIVTTEDVL 238
Cdd:PRK09112 185 LPTIRSRCQPISLKPLDDDELKKALSHLGSSQGS--DGEITEALLQRSKGSVRKALLL----LNYGGlEIIATIDQL 255
PRK08699 PRK08699
DNA polymerase III subunit delta'; Validated
35-305 2.40e-25

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181538 [Multi-domain]  Cd Length: 325  Bit Score: 106.88  E-value: 2.40e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  35 EKVSHAYLFSGPRGTGKTTIAKVFAKAINCEH-APVAEPCNECPSCLGITQGSISDVLEIDAASN---NG-------VDE 103
Cdd:PRK08699  18 ERRPNAWLFAGKKGIGKTAFARFAAQALLCETpAPGHKPCGECMSCHLFGQGSHPDFYEITPLSDepeNGrkllqikIDA 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 104 IRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHKIPPTIISRCQRFE--------- 174
Cdd:PRK08699  98 VREIIDNVYLTSVRGGLRVILIHPAESMNLQAANSLLKVLEEPPPQVVFLLVSHAADKVLPTIKSRCRKMVlpapsheea 177
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 175 ---FRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEG-GMRDALSLIDqaisYSDEIVTTEDVLAVTGSVSQQYLG 250
Cdd:PRK08699 178 layLRERGVAEPEERLAFHSGAPLFDEEPELRALRIKLLDIlAEPRLLKILD----YAALFDKEKLPLAVFVGWMQKWLV 253
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 228822350 251 NLVECIRENDVSRALQIIDEM--MSKGKDPVRFMEdfiyyYRDMLLyQTSP----------QLEHML 305
Cdd:PRK08699 254 DLGLCLQHMKPVYYPAYEDRLlqTASGFRPRNVFA-----AEDMLK-QLAPygfhtlnvkmQIEHLL 314
HLD_clamp_pol_III_gamma_tau cd18137
helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit ...
178-242 1.09e-24

helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit gamma/tau is part of the DNA polymerase III holoenzyme. Gamma and tau subunits are isoforms, both containing the helical lid domain. Gamma interacts with the delta subunit to transfer the beta subunit on the DNA while tau serves as a scaffold to help in the dimerization of the core complex. Both are members of the clamp-loader clade of the AAA+ superfamily.


Pssm-ID: 350839 [Multi-domain]  Cd Length: 65  Bit Score: 97.19  E-value: 1.09e-24
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 228822350 178 ISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDEIVTTEDVLAVTG 242
Cdd:cd18137    1 ISVEDIVGRLAHILEKEGIEIEDEALELIARAAEGSMRDALSLLDQAIAFGGGRVTLDDVREMLG 65
PRK06964 PRK06964
DNA polymerase III subunit delta'; Validated
33-173 2.05e-23

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235898 [Multi-domain]  Cd Length: 342  Bit Score: 101.38  E-value: 2.05e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  33 LQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEH-APVAEPCNECPSCLGITQGSISD-------VLEIDAASNNGVDEI 104
Cdd:PRK06964  16 LRARLPHALLLHGQAGIGKLDFAQHLAQGLLCETpQPDGEPCGTCAACNWFAQGNHPDyrivrpeALAAEAPGAADEAKE 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 105 RDIRDKVKY--APSaveyKVYIIDEVHMLS--MG----------------------AFNALLKTLEEPPGHVIFILATTE 158
Cdd:PRK06964  96 ADADEGGKKtkAPS----KEIKIEQVRALLdfCGvgthrggarvvvlypaealnvaAANALLKTLEEPPPGTVFLLVSAR 171
                        170
                 ....*....|....*
gi 228822350 159 PHKIPPTIISRCQRF 173
Cdd:PRK06964 172 IDRLLPTILSRCRQF 186
PRK06871 PRK06871
DNA polymerase III subunit delta'; Validated
31-171 6.22e-22

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180738 [Multi-domain]  Cd Length: 325  Bit Score: 96.73  E-value: 6.22e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  31 ALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCLGITQGSISDVLEIDAASNN--GVDEIRDIR 108
Cdd:PRK06871  17 AFQQGLGHHALLFKADSGLGTEQLIRALAQWLMCQTPQGDQPCGQCHSCHLFQAGNHPDFHILEPIDNKdiGVDQVREIN 96
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 228822350 109 DKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHKIPPTIISRCQ 171
Cdd:PRK06871  97 EKVSQHAQQGGNKVVYIQGAERLTEAAANALLKTLEEPRPNTYFLLQADLSAALLPTIYSRCQ 159
PLN03025 PLN03025
replication factor C subunit; Provisional
10-264 9.93e-22

replication factor C subunit; Provisional


Pssm-ID: 178596 [Multi-domain]  Cd Length: 319  Bit Score: 96.34  E-value: 9.93e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  10 WRPQKFEDVVGQKHVTKTLQnALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAIncehapvaepcnecpscLGITqgSISD 89
Cdd:PLN03025   7 YRPTKLDDIVGNEDAVSRLQ-VIARDGNMPNLILSGPPGTGKTTSILALAHEL-----------------LGPN--YKEA 66
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  90 VLEIDAASNNGVDEIRD-----IRDKVKYAPSavEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHKIPP 164
Cdd:PLN03025  67 VLELNASDDRGIDVVRNkikmfAQKKVTLPPG--RHKIVILDEADSMTSGAQQALRRTMEIYSNTTRFALACNTSSKIIE 144
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 165 TIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIdQAISYSDEIVTTEDVLAVTGSV 244
Cdd:PLN03025 145 PIQSRCAIVRFSRLSDQEILGRLMKVVEAEKVPYVPEGLEAIIFTADGDMRQALNNL-QATHSGFGFVNQENVFKVCDQP 223
                        250       260
                 ....*....|....*....|
gi 228822350 245 SQQYLGNLVECIRENDVSRA 264
Cdd:PLN03025 224 HPLHVKNIVRNCLKGKFDDA 243
PRK07471 PRK07471
DNA polymerase III subunit delta'; Validated
39-223 8.50e-21

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236022 [Multi-domain]  Cd Length: 365  Bit Score: 94.33  E-value: 8.50e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  39 HAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCLG----------ITQGSISDVLEIDAASNNG-------- 100
Cdd:PRK07471  42 HAWLIGGPQGIGKATLAYRMARFLLATPPPGGDGAVPPPTSLAidpdhpvarrIAAGAHGGLLTLERSWNEKgkrlrtvi 121
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 101 -VDEIRDIrdKVKYAPSAVE--YKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHKIPPTIISRCQRFEFRK 177
Cdd:PRK07471 122 tVDEVREL--ISFFGLTAAEggWRVVIVDTADEMNANAANALLKVLEEPPARSLFLLVSHAPARLLPTIRSRCRKLRLRP 199
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 228822350 178 ISVNDiverLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQ 223
Cdd:PRK07471 200 LAPED----VIDALAAAGPDLPDDPRAALAALAEGSVGRALRLAGG 241
PRK05564 PRK05564
DNA polymerase III subunit delta'; Validated
14-354 4.98e-20

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180132 [Multi-domain]  Cd Length: 313  Bit Score: 90.86  E-value: 4.98e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  14 KFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAIncehapvaepcnecpscLGITQGSIS-DVLE 92
Cdd:PRK05564   2 SFHTIIGHENIKNRIKNSIIKNRFSHAHIIVGEDGIGKSLLAKEIALKI-----------------LGKSQQREYvDIIE 64
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  93 IDAASNN--GVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHKIPPTIISRC 170
Cdd:PRK05564  65 FKPINKKsiGVDDIRNIIEEVNKKPYEGDKKVIIIYNSEKMTEQAQNAFLKTIEEPPKGVFIILLCENLEQILDTIKSRC 144
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 171 QRFEFRKISVNDIVERLSTVVTNEGTQvedealqivaraaeggmrdalsLIDQAISYSDEIVTTEDVLAVTGSVS--QQY 248
Cdd:PRK05564 145 QIYKLNRLSKEEIEKFISYKYNDIKEE----------------------EKKSAIAFSDGIPGKVEKFIEDDSLKniRNM 202
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 249 LGNLVECIRENDVSRALQIIDEMMSKGKDPVRFMEDFIYYYRDMLLYQTSPQLEHMLERVIVDDqFRKLSEEMQPEVIYE 328
Cdd:PRK05564 203 SLEILKDIKKSNINILLKYENFLIKYKENWEEILTCILSYIRDSLLYKETGNEELIINIDKIED-IKHISEKFSYKKLNK 281
                        330       340
                 ....*....|....*....|....*..
gi 228822350 329 IIHTLSKGQQEM-KWTNHPRIFLEVVM 354
Cdd:PRK05564 282 MIEIINDTRDNLsSNVNPTLVFDSMLI 308
PRK07276 PRK07276
DNA polymerase III subunit delta'; Validated
21-177 2.64e-19

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180916 [Multi-domain]  Cd Length: 290  Bit Score: 88.54  E-value: 2.64e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  21 QKHVTKTLQNALLQEKVSHAYLFSGprGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCLGITQGSISDVLEIdaASNNG 100
Cdd:PRK07276   7 QPKVFQRFQTILEQDRLNHAYLFSG--DFASFEMALFLAQSLFCEQKEGVLPCGHCRSCRLIEQGEFSDVTVI--EPQGQ 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 101 VDEIRDIRDKVK-YAPSAVEYK--VYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHKIPPTIISRCQRFEFRK 177
Cdd:PRK07276  83 VIKTDTIRELVKnFSQSGYEGKqqVFIIKDADKMHVNAANSLLKVIEEPQSEIYIFLLTNDENKVLPTIKSRTQIFHFPK 162
PRK04132 PRK04132
replication factor C small subunit; Provisional
91-241 5.41e-18

replication factor C small subunit; Provisional


Pssm-ID: 235223 [Multi-domain]  Cd Length: 846  Bit Score: 87.97  E-value: 5.41e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  91 LEIDAASNNGVDEIRD-IRDKVKYAP-SAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHKIPPTIIS 168
Cdd:PRK04132 600 LELNASDERGINVIREkVKEFARTKPiGGASFKIIFLDEADALTQDAQQALRRTMEMFSSNVRFILSCNYSSKIIEPIQS 679
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 228822350 169 RCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIdQAISYSDEIVTTEDVLAVT 241
Cdd:PRK04132 680 RCAIFRFRPLRDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMRRAINIL-QAAAALDDKITDENVFLVA 751
PRK04195 PRK04195
replication factor C large subunit; Provisional
11-242 3.88e-17

replication factor C large subunit; Provisional


Pssm-ID: 235250 [Multi-domain]  Cd Length: 482  Bit Score: 84.20  E-value: 3.88e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  11 RPQKFEDVVGQKHVTKTLQ---NALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEhapvaepcnecpsclgitqgsi 87
Cdd:PRK04195   9 RPKTLSDVVGNEKAKEQLRewiESWLKGKPKKALLLYGPPGVGKTSLAHALANDYGWE---------------------- 66
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  88 sdVLEIDAASNNGVDEIRdirdkvKYAPSA--------VEYKVYIIDEVHMLS----MGAFNALLKTLEEPPGHVIfiLA 155
Cdd:PRK04195  67 --VIELNASDQRTADVIE------RVAGEAatsgslfgARRKLILLDEVDGIHgnedRGGARAILELIKKAKQPII--LT 136
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 156 TTEPHKIPP-TIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDAlslID--QAISYSDEIV 232
Cdd:PRK04195 137 ANDPYDPSLrELRNACLMIEFKRLSTRSIVPVLKRICRKEGIECDDEALKEIAERSGGDLRSA---INdlQAIAEGYGKL 213
                        250
                 ....*....|
gi 228822350 233 TTEDVLAVTG 242
Cdd:PRK04195 214 TLEDVKTLGR 223
PRK06090 PRK06090
DNA polymerase III subunit delta'; Validated
28-225 1.17e-16

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180394 [Multi-domain]  Cd Length: 319  Bit Score: 81.00  E-value: 1.17e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  28 LQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPvAEPCNECPSCLGITQGSISDVLEIDAASNNG---VDEI 104
Cdd:PRK06090  15 WKAGLDAGRIPGALLLQSDEGLGVESLVELFSRALLCQNYQ-SEACGFCHSCELMQSGNHPDLHVIKPEKEGKsitVEQI 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 105 RDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHKIPPTIISRCQRFEFRKISVNDIV 184
Cdd:PRK06090  94 RQCNRLAQESSQLNGYRLFVIEPADAMNESASNALLKTLEEPAPNCLFLLVTHNQKRLLPTIVSRCQQWVVTPPSTAQAM 173
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 228822350 185 ERLStvvtNEGTQVEDEALQ------IVARAA--EGGMRDALSLIDQAI 225
Cdd:PRK06090 174 QWLK----GQGITVPAYALKlnmgspLKTLAMmkEGGLEKYHKLERQLV 218
44 PHA02544
clamp loader, small subunit; Provisional
5-262 3.83e-16

clamp loader, small subunit; Provisional


Pssm-ID: 222866 [Multi-domain]  Cd Length: 316  Bit Score: 79.65  E-value: 3.83e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   5 ALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFakaincehapvaepCNEcpscLGItq 84
Cdd:PHA02544  10 MWEQKYRPSTIDECILPAADKETFKSIVKKGRIPNMLLHSPSPGTGKTTVAKAL--------------CNE----VGA-- 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  85 gsisDVLEIDAASNNgvdeIRDIRDKVKYAPSAVEY----KVYIIDEVHMLSMGAFNALLKTL-EEPPGHVIFILATTEP 159
Cdd:PHA02544  70 ----EVLFVNGSDCR----IDFVRNRLTRFASTVSLtgggKVIIIDEFDRLGLADAQRHLRSFmEAYSKNCSFIITANNK 141
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 160 HKIPPTIISRCQRFEFR------KISVN-DIVERLSTVVTNEGTQVEDEAL-QIVARAAEggmrDALSLIDQAISYSDEI 231
Cdd:PHA02544 142 NGIIEPLRSRCRVIDFGvptkeeQIEMMkQMIVRCKGILEAEGVEVDMKVLaALVKKNFP----DFRRTINELQRYASTG 217
                        250       260       270
                 ....*....|....*....|....*....|.
gi 228822350 232 VTTEDVLAVTGSVSqqyLGNLVECIRENDVS 262
Cdd:PHA02544 218 KIDAGILSEVTNSD---IDDVVEALKAKDFK 245
PRK05917 PRK05917
DNA polymerase III subunit delta'; Validated
34-170 2.14e-15

DNA polymerase III subunit delta'; Validated


Pssm-ID: 102059 [Multi-domain]  Cd Length: 290  Bit Score: 76.76  E-value: 2.14e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  34 QEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEpcnecpscLGITQGSISDVLEIDAASNNGVDEI---RDIRDK 110
Cdd:PRK05917  15 DQKVPSAIILHGQDLSNLSARAYELASLILKETSPEAA--------YKISQKIHPDIHEFSPQGKGRLHSIetpRAIKKQ 86
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 111 VKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHKIPPTIISRC 170
Cdd:PRK05917  87 IWIHPYESPYKIYIIHEADRMTLDAISAFLKVLEDPPQHGVIILTSAKPQRLPPTIRSRS 146
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
19-177 2.45e-15

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 73.33  E-value: 2.45e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  19 VGQKHVTKTLQNALLQEKVSHaYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPcnecpsclgitqgSISDVLEIDA-AS 97
Cdd:cd00009    1 VGQEEAIEALREALELPPPKN-LLLYGPPGTGKTTLARAIANELFRPGAPFLYL-------------NASDLLEGLVvAE 66
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  98 NNGVDEIRDIRDKVKYApsavEYKVYIIDEVHMLSMGAFNALLKTLEE------PPGHVIFILATT--EPHKIPPTIISR 169
Cdd:cd00009   67 LFGHFLVRLLFELAEKA----KPGVLFIDEIDSLSRGAQNALLRVLETlndlriDRENVRVIGATNrpLLGDLDRALYDR 142

                 ....*....
gi 228822350 170 C-QRFEFRK 177
Cdd:cd00009  143 LdIRIVIPL 151
PRK08769 PRK08769
DNA polymerase III subunit delta'; Validated
10-176 5.28e-15

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181551 [Multi-domain]  Cd Length: 319  Bit Score: 76.15  E-value: 5.28e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  10 WRPQKFEDVVGqkhvtktlqnALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAI--NCEHAPVAEPCNECpsclgITQGSI 87
Cdd:PRK08769   8 WQQRAYDQTVA----------ALDAGRLGHGLLICGPEGLGKRAVALALAEHVlaSGPDPAAAQRTRQL-----IAAGTH 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  88 SDVLEIDAASNNGVD---------EIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEP-PGHVIFiLATT 157
Cdd:PRK08769  73 PDLQLVSFIPNRTGDklrteivieQVREISQKLALTPQYGIAQVVIVDPADAINRAACNALLKTLEEPsPGRYLW-LISA 151
                        170
                 ....*....|....*....
gi 228822350 158 EPHKIPPTIISRCQRFEFR 176
Cdd:PRK08769 152 QPARLPATIRSRCQRLEFK 170
PRK07132 PRK07132
DNA polymerase III subunit delta'; Validated
26-188 2.95e-14

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180855 [Multi-domain]  Cd Length: 299  Bit Score: 73.60  E-value: 2.95e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  26 KTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPcNECPSclgitQGSISDVLEIDAASNNGVDEIR 105
Cdd:PRK07132   6 KFLDNSATQNKISHSFLLKSNYNEDIDEKILYFLNKFNNLQITNLNE-QELPA-----NIILFDIFDKDLSKSEFLSAIN 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 106 DIrdkVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHKIPPTIISRCQRFEFRKISVNDIVE 185
Cdd:PRK07132  80 KL---YFSSFVQSQKKILIIKNIEKTSNSLLNALLKTIEEPPKDTYFLLTTKNINKVLPTIVSRCQVFNVKEPDQQKILA 156

                 ...
gi 228822350 186 RLS 188
Cdd:PRK07132 157 KLL 159
AAA pfam00004
ATPase family associated with various cellular activities (AAA); AAA family proteins often ...
41-175 5.99e-14

ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.


Pssm-ID: 459627 [Multi-domain]  Cd Length: 130  Bit Score: 68.77  E-value: 5.99e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   41 YLFSGPRGTGKTTIAKVFAKAINCEhapvaepcnecpsclgitqgsisdVLEIDAAS--NNGVDE-IRDIRDKVKYApSA 117
Cdd:pfam00004   1 LLLYGPPGTGKTTLAKAVAKELGAP------------------------FIEISGSElvSKYVGEsEKRLRELFEAA-KK 55
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 228822350  118 VEYKVYIIDEVHML-----------SMGAFNALLKTLEEP---PGHVIFILATTEPHKIPPTIISRCQRFEF 175
Cdd:pfam00004  56 LAPCVIFIDEIDALagsrgsggdseSRRVVNQLLTELDGFtssNSKVIVIAATNRPDKLDPALLGRFDRIIE 127
PRK05818 PRK05818
DNA polymerase III subunit delta'; Validated
58-183 9.08e-14

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235618 [Multi-domain]  Cd Length: 261  Bit Score: 71.40  E-value: 9.08e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  58 FAKAINCEHApvAEPCNECPSCLGITQGSISDVLEI-DAASNNGVDEIRDIRDKVKY-APSAVEYKVYIIDEVHMLSMGA 135
Cdd:PRK05818  27 YLTSIVCTKA--NGFCKTCESCLKILNGKYNDFYLIfDQKNPIKKEDALSIINKLNRpSVESNGKKIYIIYGIEKLNKQS 104
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 228822350 136 FNALLKTLEEPPGHVIFILATTEPHKIPPTIISRC---------QRFEFrKISVNDI 183
Cdd:PRK05818 105 ANSLLKLIEEPPKNTYGIFTTRNENNILNTILSRCvqyvvlskeKKVPF-KVESNDR 160
PRK13341 PRK13341
AAA family ATPase;
11-221 2.57e-13

AAA family ATPase;


Pssm-ID: 237354 [Multi-domain]  Cd Length: 725  Bit Score: 72.78  E-value: 2.57e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  11 RPQKFEDVVGQKHVT---KTLQNALLQEKVSHAyLFSGPRGTGKTTIAKVFAKAINCEHApvaepcnecpsclgitqgSI 87
Cdd:PRK13341  23 RPRTLEEFVGQDHILgegRLLRRAIKADRVGSL-ILYGPPGVGKTTLARIIANHTRAHFS------------------SL 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  88 SDVLeidaasnNGVdeiRDIRDKVKYAPSAVEY----KVYIIDEVHMLSMGAFNALLKTLEEppGHVIFILATTE-PH-K 161
Cdd:PRK13341  84 NAVL-------AGV---KDLRAEVDRAKERLERhgkrTILFIDEVHRFNKAQQDALLPWVEN--GTITLIGATTEnPYfE 151
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 228822350 162 IPPTIISRCQRFEFRKISVNDIVERLSTVVTNEG-------TQVEDEALQIVARAAEGgmrDALSLI 221
Cdd:PRK13341 152 VNKALVSRSRLFRLKSLSDEDLHQLLKRALQDKErgygdrkVDLEPEAEKHLVDVANG---DARSLL 215
PRK07993 PRK07993
DNA polymerase III subunit delta'; Validated
10-170 8.62e-13

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181190 [Multi-domain]  Cd Length: 334  Bit Score: 69.71  E-value: 8.62e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  10 WRPQKFEDVVGQKHvtktlqnallQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCLGITQGSISD 89
Cdd:PRK07993   6 WLRPDYEQLVGSYQ----------AGRGHHALLIQALPGMGDDALIYALSRWLMCQQPQGHKSCGHCRGCQLMQAGTHPD 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  90 --VLEIDAASNN-GVDEIRDIRDKVkYAPSAVE-YKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHKIPPT 165
Cdd:PRK07993  76 yyTLTPEKGKSSlGVDAVREVTEKL-YEHARLGgAKVVWLPDAALLTDAAANALLKTLEEPPENTWFFLACREPARLLAT 154

                 ....*
gi 228822350 166 IISRC 170
Cdd:PRK07993 155 LRSRC 159
COG1223 COG1223
Predicted ATPase, AAA+ superfamily [General function prediction only];
15-277 2.04e-12

Predicted ATPase, AAA+ superfamily [General function prediction only];


Pssm-ID: 440836 [Multi-domain]  Cd Length: 246  Bit Score: 67.22  E-value: 2.04e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  15 FEDVVGQ-------KHVTKTLQNALLQEK----VSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAepcnecPSCLgit 83
Cdd:COG1223    1 LDDVVGQeeakkklKLIIKELRRRENLRKfglwPPRKILFYGPPGTGKTMLAEALAGELKLPLLTVR------LDSL--- 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  84 qgsISDVLEiDAASNngvdeIRDIRDKVKYAPSaveykVYIIDEVHML--------SMG----AFNALLKTLEEPPGHVI 151
Cdd:COG1223   72 ---IGSYLG-ETARN-----LRKLFDFARRAPC-----VIFFDEFDAIakdrgdqnDVGevkrVVNALLQELDGLPSGSV 137
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 152 FILATTEPHKIPPTIISRCQ-RFEFRKISVNDIVE----RLSTVVTNegtqvEDEALQIVARAAEGgmrdalslidqaIS 226
Cdd:COG1223  138 VIAATNHPELLDSALWRRFDeVIEFPLPDKEERKEilelNLKKFPLP-----FELDLKKLAKKLEG------------LS 200
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|.
gi 228822350 227 YSDeivtTEDVLavTGSVSQQYLGNLvECIRENDVSRALQIIDEMMSKGKD 277
Cdd:COG1223  201 GAD----IEKVL--KTALKKAILEDR-EKVTKEDLEEALKQRKERKKEPKK 244
HolA COG1466
DNA polymerase III, delta subunit [Replication, recombination and repair];
119-282 8.83e-11

DNA polymerase III, delta subunit [Replication, recombination and repair];


Pssm-ID: 441075 [Multi-domain]  Cd Length: 305  Bit Score: 63.35  E-value: 8.83e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 119 EYKVYIIDEVHMLSMG--AFNALLKTLEEPPGHVIFILATTEP---HKIPPTIISRCQRFEFRKISVNDIVERLSTVVTN 193
Cdd:COG1466   62 ERRLVIVRNAEFLKKPgeGLEALEAYLANPPPDTVLVLTAGKLdkrKKLFKALEKAGVVVECYPLKERELPAWIRQRLKA 141
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 194 EGTQVEDEALQIVARAAEGGMRDALSLIDQAISY--SDEIVTTEDVLAVTGSVSQQYLGNLVECIRENDVSRALQIIDEM 271
Cdd:COG1466  142 AGLRIDPDAAQLLAERVGGDLLALAQELEKLALYagDGGTITLEDVEALVGDSAEFNVFDLADALLAGDAARALRILRRL 221
                        170
                 ....*....|.
gi 228822350 272 MSKGKDPVRFM 282
Cdd:COG1466  222 LAEGEEPVLIL 232
SpoVK COG0464
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ...
8-239 1.15e-09

AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];


Pssm-ID: 440232 [Multi-domain]  Cd Length: 397  Bit Score: 60.31  E-value: 1.15e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   8 RTWRPQKFEDVVGQKHVTKTLQNALL----QEKVSHAY--------LFSGPRGTGKTTIAKVFAKAINcehapvaepcne 75
Cdd:COG0464  149 LELREAILDDLGGLEEVKEELRELVAlplkRPELREEYglppprglLLYGPPGTGKTLLARALAGELG------------ 216
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  76 cpsclgitqgsiSDVLEIDAAsnngvdEIRD---------IRDKVKYApSAVEYKVYIIDEVHMLSMG-----------A 135
Cdd:COG0464  217 ------------LPLIEVDLS------DLVSkyvgeteknLREVFDKA-RGLAPCVLFIDEADALAGKrgevgdgvgrrV 277
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 136 FNALLKTLEEPPGHVIFILATTEPHKIPPTIISRCQR-FEFRKIsvnDIVERLS--TVVTNEGTQVEDEALQIVARAAEG 212
Cdd:COG0464  278 VNTLLTEMEELRSDVVVIAATNRPDLLDPALLRRFDEiIFFPLP---DAEERLEifRIHLRKRPLDEDVDLEELAEATEG 354
                        250       260       270
                 ....*....|....*....|....*....|..
gi 228822350 213 G----MRDAL-SLIDQAISYSDEIVTTEDVLA 239
Cdd:COG0464  355 LsgadIRNVVrRAALQALRLGREPVTTEDLLE 386
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
41-178 3.71e-09

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 55.46  E-value: 3.71e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350    41 YLFSGPRGTGKTTIAKVFAKAINCEHAPVAEpCNECPSCLGITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPsaveY 120
Cdd:smart00382   5 ILIVGPPGSGKTTLARALARELGPPGGGVIY-IDGEDILEEVLDQLLLIIVGGKKASGSGELRLRLALALARKLK----P 79
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 228822350   121 KVYIIDEVHMLSMGAFNALL--------KTLEEPPGHVIFILATTEPHKIPPTIISR--CQRFEFRKI 178
Cdd:smart00382  80 DVLILDEITSLLDAEQEALLllleelrlLLLLKSEKNLTVILTTNDEKDLGPALLRRrfDRRIVLLLI 147
RecA-like_protease cd19481
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ...
41-176 2.01e-08

proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410889 [Multi-domain]  Cd Length: 158  Bit Score: 53.83  E-value: 2.01e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  41 YLFSGPRGTGKTTIAKVFAkaincehapvaepcNECPSCLGITQGSISdvleIDAASNNGVDEIRDI-RDKVKYAPSave 119
Cdd:cd19481   29 ILLYGPPGTGKTLLAKALA--------------GELGLPLIVVKLSSL----LSKYVGESEKNLRKIfERARRLAPC--- 87
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 228822350 120 ykVYIIDEVHMLSM------------GAFNALLKTLEEPP--GHVIFILATTEPHKIPPTIIsRCQRFEFR 176
Cdd:cd19481   88 --ILFIDEIDAIGRkrdssgesgelrRVLNQLLTELDGVNsrSKVLVIAATNRPDLLDPALL-RPGRFDEV 155
ruvB PRK00080
Holliday junction branch migration DNA helicase RuvB;
11-235 4.51e-08

Holliday junction branch migration DNA helicase RuvB;


Pssm-ID: 234619 [Multi-domain]  Cd Length: 328  Bit Score: 55.14  E-value: 4.51e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  11 RPQKFEDVVGQKHVTKTL----QNALLQEKV-SHAyLFSGPRGTGKTTIAKVFAkaincehapvaepcNECPSCLGITQG 85
Cdd:PRK00080  20 RPKSLDEFIGQEKVKENLkifiEAAKKRGEAlDHV-LLYGPPGLGKTTLANIIA--------------NEMGVNIRITSG 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  86 --------------SIS--DVLEIdaasnngvDEI----RDIrDKVKYapSAVE-YKVYIIdevhmlsMGA-FNALLKTL 143
Cdd:PRK00080  85 palekpgdlaailtNLEegDVLFI--------DEIhrlsPVV-EEILY--PAMEdFRLDIM-------IGKgPAARSIRL 146
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 144 EEPPghviFIL--ATTEPHKIPPTIISR---CQRFEFrkISVND---IVERLSTVVtneGTQVEDEALQIVARAAEGGMR 215
Cdd:PRK00080 147 DLPP----FTLigATTRAGLLTSPLRDRfgiVQRLEF--YTVEElekIVKRSARIL---GVEIDEEGALEIARRSRGTPR 217
                        250       260
                 ....*....|....*....|....
gi 228822350 216 DALSLI----DQAISYSDEIVTTE 235
Cdd:PRK00080 218 IANRLLrrvrDFAQVKGDGVITKE 241
COG2842 COG2842
Bacteriophage DNA transposition protein, AAA+ family ATPase [Mobilome: prophages, transposons]; ...
25-247 5.02e-08

Bacteriophage DNA transposition protein, AAA+ family ATPase [Mobilome: prophages, transposons];


Pssm-ID: 442090 [Multi-domain]  Cd Length: 254  Bit Score: 54.19  E-value: 5.02e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  25 TKTLQN--ALLQEKVSHAY--LFSGPRGTGKTTIAKVFAKaincEHAPV----AEPCNECPSCLgitqGSISDVLEIDAA 96
Cdd:COG2842   33 TKNVRRfaEALDEARALPGigVVYGESGVGKTTAAREYAN----RNPNViyvtASPSWTSKELL----EELAEELGIPAP 104
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  97 SNNGVDEIRDIRDKVKYAPSAVeykvyIIDEVHMLSMGAFNaLLKTLEEPPGhVIFILATTEphKIPPTIISRCQ----- 171
Cdd:COG2842  105 PGTIADLRDRILERLAGTGRLL-----IIDEADHLKPKALE-ELRDIHDETG-VGVVLIGME--RLPAKLKRYEQlysri 175
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 172 --RFEFRKISVND---IVERLSTVvtnegtqVEDEALQIVARAAEGGMR---DALSLIDQ-AISYSDEIVTTEDVLAVTG 242
Cdd:COG2842  176 gfWVEFKPLSLEDvraLAEAWGEL-------TDPDLLELLHRITRGNLRrldRTLRLAARaAKRNGLTKITLDHVRAAAL 248

                 ....*
gi 228822350 243 SVSQQ 247
Cdd:COG2842  249 MLGEG 253
DNA_pol3_gamma3 pfam12169
DNA polymerase III subunits gamma and tau domain III; This domain family is found in bacteria, ...
232-358 6.25e-08

DNA polymerase III subunits gamma and tau domain III; This domain family is found in bacteria, and is approximately 110 amino acids in length. The family is found in association with pfam00004. Domains I-III are shared between the tau and the gamma subunits, while most of the DnaB-binding Domain IV and all of the alpha-interacting Domain V are unique to tau.


Pssm-ID: 432379 [Multi-domain]  Cd Length: 143  Bit Score: 51.89  E-value: 6.25e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  232 VTTEDVLAVTGSVSQQYLGNLVECIRENDVSRALQIIDEMMSKGKDPVRFMEDFIYYYRDMLLYQTSPQLEHMLErvIVD 311
Cdd:pfam12169   1 VTAAQVRDMLGLADRGRVLDLLEALLEGDAAAALAELRDQYDAGADPVVVLRDLLELIHNLTRLKVAPDAADDLL--LPE 78
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 228822350  312 DQFRKL---SEEMQPEVIYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQLC 358
Cdd:pfam12169  79 EERARLaelAEKLSPEVLHRLWQMLLKGIEEVPNAPDPRQAAEMVLLRLA 128
PRK08485 PRK08485
DNA polymerase III subunit delta'; Validated
104-259 2.37e-07

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236274 [Multi-domain]  Cd Length: 206  Bit Score: 51.57  E-value: 2.37e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 104 IRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHKIPPTIISRCQRFEFR------- 176
Cdd:PRK08485  39 IEDAKEVIAEAYIAESEEKIIVIAAPSYGIEAQNALLKILEEPPKNICFIIVAKSKNLLLPTIRSRLIIEKRKqkkpvkp 118
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350 177 ------KISVNDIVERLstvvtNEGTQVE----DEALQIVARAAEGGMRDALSLIDQAISYSDEIVTTEDVLAVTGSVSQ 246
Cdd:PRK08485 119 ldldlkKLDLKDIYEFL-----KELEKENklskEELKELIESLLKECVKYKIPLNEEELEYFDKAIKLADLNAKSSYVLL 193
                        170
                 ....*....|...
gi 228822350 247 QYLGNLVECIREN 259
Cdd:PRK08485 194 PLLLSLLEKKKTP 206
HLD_clamp_RFC cd18140
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein ...
178-241 3.98e-07

helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein clamp loader complex that forms a stable ATP-dependent complex with the sliding clamp, PCNA, which binds specifically to primed DNA. RFC subunits belong to the clamp loader clade of the AAA+ superfamily.


Pssm-ID: 350842 [Multi-domain]  Cd Length: 63  Bit Score: 47.14  E-value: 3.98e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 228822350 178 ISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIdQAISYSDEIVTTEDVLAVT 241
Cdd:cd18140    1 LSKEQIVKRLREICKKEGVKIDEEALEAIAEKSEGDMRKAINDL-QAAAAGGGVITEEDVYEVA 63
PRK06581 PRK06581
DNA polymerase III subunit delta'; Validated
96-170 9.21e-07

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235833 [Multi-domain]  Cd Length: 263  Bit Score: 50.61  E-value: 9.21e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 228822350  96 ASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHKIPPTIISRC 170
Cdd:PRK06581  66 AKNISIEQIRKLQDFLSKTSAISGYKVAIIYSAELMNLNAANSCLKILEDAPKNSYIFLITSRAASIISTIRSRC 140
RuvB_N pfam05496
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the ...
11-60 3.00e-06

Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the RuvABC revolvasome which catalyzes the resolution of Holliday junctions that arise during genetic recombination and DNA repair. Branch migration is catalyzed by the RuvB protein that is targeted to the Holliday junction by the structure specific RuvA protein. This family contains the N-terminal region of the protein.


Pssm-ID: 398900 [Multi-domain]  Cd Length: 159  Bit Score: 47.49  E-value: 3.00e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 228822350   11 RPQKFEDVVGQKHVTKTLQ---NALLQ--EKVSHAyLFSGPRGTGKTTIAKVFAK 60
Cdd:pfam05496   2 RPRTLDEYIGQEKVKENLKifiEAAKQrgEALDHV-LLYGPPGLGKTTLANIIAN 55
HLD_clamp cd18133
helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit ...
186-241 2.76e-05

helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit complexes that play an important role in DNA replication. They open sliding clamps for assembly and close them around DNA, specifically targeting them to sites where DNA synthesis is initiated and orienting them correctly for replication. The subunits belong to the clamp loader clade of AAA+ superfamily.


Pssm-ID: 350838 [Multi-domain]  Cd Length: 65  Bit Score: 42.07  E-value: 2.76e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 228822350 186 RLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAI-SYSDEIVTTEDVLAVT 241
Cdd:cd18133    9 RLAAIAEQEKLKLDDAALQALAYISEGDLRKALNALQRAAaLGDDGKISLDRVYQAV 65
AAA_22 pfam13401
AAA domain;
42-155 4.31e-05

AAA domain;


Pssm-ID: 379165 [Multi-domain]  Cd Length: 129  Bit Score: 43.48  E-value: 4.31e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   42 LFSGPRGTGKTTIAKVFAKAINCEHAPVAepCNECPSclgitQGSISDVL-----EIDAASNNGVDEIRDIRDKVKYAPS 116
Cdd:pfam13401   9 VLTGESGTGKTTLLRRLLEQLPEVRDSVV--FVDLPS-----GTSPKDLLrallrALGLPLSGRLSKEELLAALQQLLLA 81
                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 228822350  117 AVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILA 155
Cdd:pfam13401  82 LAVAVVLIIDEAQHLSLEALEELRDLLNLSSKLLQLILV 120
RuvB COG2255
Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, ...
11-60 8.34e-05

Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, recombination and repair];


Pssm-ID: 441856 [Multi-domain]  Cd Length: 337  Bit Score: 45.07  E-value: 8.34e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 228822350  11 RPQKFEDVVGQKHVTKTL----QNALL-QEKVSHAyLFSGPRGTGKTTIAKVFAK 60
Cdd:COG2255   23 RPKRLDEYIGQEKVKENLkifiEAAKKrGEALDHV-LLYGPPGLGKTTLAHIIAN 76
PRK04132 PRK04132
replication factor C small subunit; Provisional
10-59 1.95e-04

replication factor C small subunit; Provisional


Pssm-ID: 235223 [Multi-domain]  Cd Length: 846  Bit Score: 44.44  E-value: 1.95e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 228822350  10 WRPQKFEDVVGQKHVTKTLQNALLQEKVSHaYLFSGPRGTGK--TTIAKVFA 59
Cdd:PRK04132  13 YRPQRLDDIVGQEHIVKRLKHYVKTGSMPH-LLFAGPPGVGKclTGDTKVIA 63
TIP49 pfam06068
TIP49 P-loop domain; This family consists of the C-terminal region of several eukaryotic and ...
122-169 1.68e-03

TIP49 P-loop domain; This family consists of the C-terminal region of several eukaryotic and archaeal RuvB-like 1 (Pontin or TIP49a) and RuvB-like 2 (Reptin or TIP49b) proteins. The N-terminal domain contains the pfam00004 domain. In zebrafish, the liebeskummer (lik) mutation, causes development of hyperplastic embryonic hearts. lik encodes Reptin, a component of a DNA-stimulated ATPase complex. Beta-catenin and Pontin, a DNA-stimulated ATPase that is often part of complexes with Reptin, are in the same genetic pathways. The Reptin/Pontin ratio serves to regulate heart growth during development, at least in part via the beta-catenin pathway. TBP-interacting protein 49 (TIP49) was originally identified as a TBP-binding protein, and two related proteins are encoded by individual genes, tip49a and b. Although the function of this gene family has not been elucidated, they are supposed to play a critical role in nuclear events because they interact with various kinds of nuclear factors and have DNA helicase activities.TIP49a has been suggested to act as an autoantigen in some patients with autoimmune diseases.


Pssm-ID: 399217 [Multi-domain]  Cd Length: 347  Bit Score: 40.76  E-value: 1.68e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  122 VYIIDEVHMLSMGAFNALLKTLEEPPGHVIfILATT------------EPHKIPPTIISR 169
Cdd:pfam06068 277 VLFIDEVHMLDIECFSFLNRALESDLAPIV-ILATNrgictirgtdiiSPHGIPLDLLDR 335
COG1373 COG1373
Predicted ATPase, AAA+ superfamily [General function prediction only];
23-151 4.66e-03

Predicted ATPase, AAA+ superfamily [General function prediction only];


Pssm-ID: 440984 [Multi-domain]  Cd Length: 405  Bit Score: 39.54  E-value: 4.66e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350  23 HVTKTLQNALlqeKVSHAYLFSGPRGTGKTTIAKVFAKA------INCEHAPVAEpcnecpsclgITQGSISDVLEidaa 96
Cdd:COG1373    8 KILDKLLKLL---DNRKAVVITGPRQVGKTTLLKQLAKElenilyINLDDPRLRA----------LAEEDPDDLLE---- 70
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 228822350  97 snngvdEIRDIRDKVKYApsaveykvyIIDEVHMLSmGAFNAlLKTL--EEPPGHVI 151
Cdd:COG1373   71 ------ALKELYPGKTYL---------FLDEIQRVP-EWEDA-LKRLvdDGRNGRFI 110
MoxR COG0714
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway ...
16-65 5.92e-03

MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 440478 [Multi-domain]  Cd Length: 292  Bit Score: 39.00  E-value: 5.92e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 228822350  16 EDVVGQKHVTKTLQNALLQEKvsHAyLFSGPRGTGKTTIAKVFAKAINCE 65
Cdd:COG0714   12 KVYVGQEELIELVLIALLAGG--HL-LLEGVPGVGKTTLAKALARALGLP 58
AAA_16 pfam13191
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ...
18-84 8.00e-03

AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.


Pssm-ID: 433025 [Multi-domain]  Cd Length: 167  Bit Score: 37.48  E-value: 8.00e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 228822350   18 VVGQKHVTKTLQNAL--LQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAE-PCNECPSCLGITQ 84
Cdd:pfam13191   2 LVGREEELEQLLDALdrVRSGRPPSVLLTGEAGTGKTTLLRELLRALERDGGYFLRgKCDENLPYSPLLE 71
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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