NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|288329341|gb|EFC67927|]
View 

glycosyl hydrolase family 26 [Prevotella sp. oral taxon 317 str. F0108]

Protein Classification

glycoside hydrolase family 26 protein( domain architecture ID 10008320)

glycoside hydrolase family 26 protein such as mannan endo-1,4-beta-mannosidase that catalyzes the endo hydrolysis of beta-1,4-linked mannan, galactomannan and glucomannan

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
ManB2 COG4124
Beta-mannanase [Carbohydrate transport and metabolism];
58-332 8.98e-48

Beta-mannanase [Carbohydrate transport and metabolism];


:

Pssm-ID: 443300  Cd Length: 330  Bit Score: 164.52  E-value: 8.98e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288329341  58 VCGDYPAVLGCELGGLELGNDKNLDGVPFDKMRQQIIAHHQKGGIVTISWHPYNPVTGKDAWNTEGDAVtavlPGGKEVA 137
Cdd:COG4124   62 VAGAGGQGAGGGGRGGALGGADNGAGAASGQLAAATTEYKLGAAALVTLASGLLAATPVSGAGGTNGLK----PGGIAHG 137

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288329341 138 KMQLWHTRLAQFLGSLKDDkghaVPVIFRPWHEMSGAWFWWGsKQCTPEQYKSLFRLTFDAMMQA-GLRNLVWSYSPNAQ 216
Cdd:COG4124  138 AYDAYLDRIADFLKSLQAG----VPVIFRPGHEMNGGWFWWG-AGADPEDYKALWRHVVDYLRNTgGLPNLIWVWSPNGG 212

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288329341 217 ANDTpEHYFLFYPGDSYVDVLGVDLYQ---YNASAVFIEQCQNEMRIMSEYAKSHNKLYALTEAGY--RNTPDAQWYSSt 291
Cdd:COG4124  213 FPSS-ADYLDYYPGDDYVDIVGLDGYNdgpTDPWQSFDELLDPGYDELRAFARAHGKPIAITETGPepDPYDKAAWITD- 290

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 288329341 292 LVPAIKGFAP--SYVlLWRNAWDkaeeNFGPAPEKTCANDFRK 332
Cdd:COG4124  291 LLDALRAKYPkiSYF-IWFNGDD----DWRVDPSPNSAAAFKK 328
 
Name Accession Description Interval E-value
ManB2 COG4124
Beta-mannanase [Carbohydrate transport and metabolism];
58-332 8.98e-48

Beta-mannanase [Carbohydrate transport and metabolism];


Pssm-ID: 443300  Cd Length: 330  Bit Score: 164.52  E-value: 8.98e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288329341  58 VCGDYPAVLGCELGGLELGNDKNLDGVPFDKMRQQIIAHHQKGGIVTISWHPYNPVTGKDAWNTEGDAVtavlPGGKEVA 137
Cdd:COG4124   62 VAGAGGQGAGGGGRGGALGGADNGAGAASGQLAAATTEYKLGAAALVTLASGLLAATPVSGAGGTNGLK----PGGIAHG 137

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288329341 138 KMQLWHTRLAQFLGSLKDDkghaVPVIFRPWHEMSGAWFWWGsKQCTPEQYKSLFRLTFDAMMQA-GLRNLVWSYSPNAQ 216
Cdd:COG4124  138 AYDAYLDRIADFLKSLQAG----VPVIFRPGHEMNGGWFWWG-AGADPEDYKALWRHVVDYLRNTgGLPNLIWVWSPNGG 212

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288329341 217 ANDTpEHYFLFYPGDSYVDVLGVDLYQ---YNASAVFIEQCQNEMRIMSEYAKSHNKLYALTEAGY--RNTPDAQWYSSt 291
Cdd:COG4124  213 FPSS-ADYLDYYPGDDYVDIVGLDGYNdgpTDPWQSFDELLDPGYDELRAFARAHGKPIAITETGPepDPYDKAAWITD- 290

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 288329341 292 LVPAIKGFAP--SYVlLWRNAWDkaeeNFGPAPEKTCANDFRK 332
Cdd:COG4124  291 LLDALRAKYPkiSYF-IWFNGDD----DWRVDPSPNSAAAFKK 328
Glyco_hydro_26 pfam02156
Glycosyl hydrolase family 26;
17-247 3.73e-41

Glycosyl hydrolase family 26;


Pssm-ID: 396639  Cd Length: 311  Bit Score: 146.66  E-value: 3.73e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288329341   17 AQQLIERLKTLQKRGVMFGHQDALFYGTTWKWEfgRSDVNDVCGDYPAVLGCEL--GGLELGN-DKNLDGvpfdKMRQQI 93
Cdd:pfam02156   9 TRSLMAFLQEQRRHSILSGHQGGLTITRTDGTQ--ASDIFNATGDFPAIYGFDMidGWDTLSIvEPKAAG----DIVQDK 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288329341   94 IAHHQKGGIVTISWHPYNPVTGKDAW--NTEGDAVTAVL--PGGKEVAKMQLWHTRLAQFLGSLKDDKghaVPVIFRPWH 169
Cdd:pfam02156  83 KAYWRMGGIIQVSSHFDNPKTQKGVFptGTTWDQTPAVLdsLPGGAYKVLNGYLDQIAEWLNNLKDEQ---VPVLFRPLH 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288329341  170 EMSGAWFWWGSK-QCTPEQYKSLFRLTFDAMMQA-GLRNLVWSYSPNAQANDTPEhyflFYPGDSYVDVLGVDLYQYNAS 247
Cdd:pfam02156 160 ENTGSWFWWGDKgQSTPEQYKQLFRYSVEYLRDVkGVRNLIWVYSPNNFWDVTEA----NYPGDEYVDIVGFDTYGPNVA 235
 
Name Accession Description Interval E-value
ManB2 COG4124
Beta-mannanase [Carbohydrate transport and metabolism];
58-332 8.98e-48

Beta-mannanase [Carbohydrate transport and metabolism];


Pssm-ID: 443300  Cd Length: 330  Bit Score: 164.52  E-value: 8.98e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288329341  58 VCGDYPAVLGCELGGLELGNDKNLDGVPFDKMRQQIIAHHQKGGIVTISWHPYNPVTGKDAWNTEGDAVtavlPGGKEVA 137
Cdd:COG4124   62 VAGAGGQGAGGGGRGGALGGADNGAGAASGQLAAATTEYKLGAAALVTLASGLLAATPVSGAGGTNGLK----PGGIAHG 137

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288329341 138 KMQLWHTRLAQFLGSLKDDkghaVPVIFRPWHEMSGAWFWWGsKQCTPEQYKSLFRLTFDAMMQA-GLRNLVWSYSPNAQ 216
Cdd:COG4124  138 AYDAYLDRIADFLKSLQAG----VPVIFRPGHEMNGGWFWWG-AGADPEDYKALWRHVVDYLRNTgGLPNLIWVWSPNGG 212

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288329341 217 ANDTpEHYFLFYPGDSYVDVLGVDLYQ---YNASAVFIEQCQNEMRIMSEYAKSHNKLYALTEAGY--RNTPDAQWYSSt 291
Cdd:COG4124  213 FPSS-ADYLDYYPGDDYVDIVGLDGYNdgpTDPWQSFDELLDPGYDELRAFARAHGKPIAITETGPepDPYDKAAWITD- 290

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 288329341 292 LVPAIKGFAP--SYVlLWRNAWDkaeeNFGPAPEKTCANDFRK 332
Cdd:COG4124  291 LLDALRAKYPkiSYF-IWFNGDD----DWRVDPSPNSAAAFKK 328
Glyco_hydro_26 pfam02156
Glycosyl hydrolase family 26;
17-247 3.73e-41

Glycosyl hydrolase family 26;


Pssm-ID: 396639  Cd Length: 311  Bit Score: 146.66  E-value: 3.73e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288329341   17 AQQLIERLKTLQKRGVMFGHQDALFYGTTWKWEfgRSDVNDVCGDYPAVLGCEL--GGLELGN-DKNLDGvpfdKMRQQI 93
Cdd:pfam02156   9 TRSLMAFLQEQRRHSILSGHQGGLTITRTDGTQ--ASDIFNATGDFPAIYGFDMidGWDTLSIvEPKAAG----DIVQDK 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288329341   94 IAHHQKGGIVTISWHPYNPVTGKDAW--NTEGDAVTAVL--PGGKEVAKMQLWHTRLAQFLGSLKDDKghaVPVIFRPWH 169
Cdd:pfam02156  83 KAYWRMGGIIQVSSHFDNPKTQKGVFptGTTWDQTPAVLdsLPGGAYKVLNGYLDQIAEWLNNLKDEQ---VPVLFRPLH 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288329341  170 EMSGAWFWWGSK-QCTPEQYKSLFRLTFDAMMQA-GLRNLVWSYSPNAQANDTPEhyflFYPGDSYVDVLGVDLYQYNAS 247
Cdd:pfam02156 160 ENTGSWFWWGDKgQSTPEQYKQLFRYSVEYLRDVkGVRNLIWVYSPNNFWDVTEA----NYPGDEYVDIVGFDTYGPNVA 235
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH