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Conserved domains on  [gi|314927087|gb|EFS90918|]
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amino acid permease [Cutibacterium acnes HL036PA3]

Protein Classification

APC family permease( domain architecture ID 1903533)

APC (amino acid/polyamine/organocation) family permease is involved in the uptake of a specific amino acid and/or polyamine substrate with the concomitant import of a proton

Gene Ontology:  GO:0055085|GO:0022857
TCDB:  2.A.3

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
AA_permease_2 super family cl45918
Amino acid permease;
4-475 0e+00

Amino acid permease;


The actual alignment was detected with superfamily member PRK11049:

Pssm-ID: 459263  Cd Length: 469  Bit Score: 619.44  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087   4 MDSATQATTPTegPTEEPQLQRGLKNRHLQLIAIGGAIGTGLFLGSGKTISLAGPSILLVYLIIGAVLFFVMRAMGELLL 83
Cdd:PRK11049   1 VDQVKVVADDQ--APAEQSLRRNLTNRHIQLIAIGGAIGTGLFMGSGKTISLAGPSIIFVYMIIGFMLFFVMRAMGELLL 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  84 SNLAYKSFADFATDLVGPGAGFYMGWTYWMCWVVIGNADTIAMCGYLAAWFPHLDKWIPATCIVLLLTCLNMVAVKLFGE 163
Cdd:PRK11049  79 SNLEYKSFSDFASDLLGPWAGYFTGWTYWFCWVVTGIADVVAITAYAQFWFPDLSDWVASLAVVLLLLSLNLATVKMFGE 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 164 MEFWFAMIKIVTIIALILVGGYLAITGFQPPrSGVpAASFSHLWDRGGFFPTGFMGFIAGFQIAIFSFQGIEMAGTAAAE 243
Cdd:PRK11049 159 MEFWFAMIKIVAIVALIVVGLVMVAMHFQSP-TGV-EASFAHLWNDGGMFPKGLSGFFAGFQIAVFAFVGIELVGTTAAE 236
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 244 TADPEHNLPKAINSIPARVLIFYVLTLGVIMAVQPWDLINPQASPFVEMFSFIGILIAFHIVNFVVLTSAASSANSGVFS 323
Cdd:PRK11049 237 TKDPEKSLPRAINSIPIRIIMFYVFALIVIMSVTPWSSVVPDKSPFVELFVLVGLPAAASVINFVVLTSAASSANSGVFS 316
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 324 TSRILYGLAREKDAPPVFAKLSSRHIPRNALILTAMCIAPAIVLVTLEDSVMDAFSLVAGVSSVLYLSVWGLILVCYLKY 403
Cdd:PRK11049 317 TSRMLFGLAQEGVAPKAFAKLSKRAVPAKGLTFSCICLLGGVVLLYVNPSVIGAFTLVTTVSAILFMFVWTIILCSYLVY 396
                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 314927087 404 LGKHPQRHAESAFKMPAGRVMSWVGILFFITILIMLGFSADSRQALIAAPVWVIFMMVLYRLLASARADHTR 475
Cdd:PRK11049 397 RKQRPHLHEKSIYKMPLGKLMCWVCMAFFAFVLVLLTLEDDTRQALIVTPLWFIALGLGYLFIGKKRAAELR 468
 
Name Accession Description Interval E-value
PRK11049 PRK11049
D-alanine/D-serine/glycine permease; Provisional
4-475 0e+00

D-alanine/D-serine/glycine permease; Provisional


Pssm-ID: 236830  Cd Length: 469  Bit Score: 619.44  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087   4 MDSATQATTPTegPTEEPQLQRGLKNRHLQLIAIGGAIGTGLFLGSGKTISLAGPSILLVYLIIGAVLFFVMRAMGELLL 83
Cdd:PRK11049   1 VDQVKVVADDQ--APAEQSLRRNLTNRHIQLIAIGGAIGTGLFMGSGKTISLAGPSIIFVYMIIGFMLFFVMRAMGELLL 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  84 SNLAYKSFADFATDLVGPGAGFYMGWTYWMCWVVIGNADTIAMCGYLAAWFPHLDKWIPATCIVLLLTCLNMVAVKLFGE 163
Cdd:PRK11049  79 SNLEYKSFSDFASDLLGPWAGYFTGWTYWFCWVVTGIADVVAITAYAQFWFPDLSDWVASLAVVLLLLSLNLATVKMFGE 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 164 MEFWFAMIKIVTIIALILVGGYLAITGFQPPrSGVpAASFSHLWDRGGFFPTGFMGFIAGFQIAIFSFQGIEMAGTAAAE 243
Cdd:PRK11049 159 MEFWFAMIKIVAIVALIVVGLVMVAMHFQSP-TGV-EASFAHLWNDGGMFPKGLSGFFAGFQIAVFAFVGIELVGTTAAE 236
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 244 TADPEHNLPKAINSIPARVLIFYVLTLGVIMAVQPWDLINPQASPFVEMFSFIGILIAFHIVNFVVLTSAASSANSGVFS 323
Cdd:PRK11049 237 TKDPEKSLPRAINSIPIRIIMFYVFALIVIMSVTPWSSVVPDKSPFVELFVLVGLPAAASVINFVVLTSAASSANSGVFS 316
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 324 TSRILYGLAREKDAPPVFAKLSSRHIPRNALILTAMCIAPAIVLVTLEDSVMDAFSLVAGVSSVLYLSVWGLILVCYLKY 403
Cdd:PRK11049 317 TSRMLFGLAQEGVAPKAFAKLSKRAVPAKGLTFSCICLLGGVVLLYVNPSVIGAFTLVTTVSAILFMFVWTIILCSYLVY 396
                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 314927087 404 LGKHPQRHAESAFKMPAGRVMSWVGILFFITILIMLGFSADSRQALIAAPVWVIFMMVLYRLLASARADHTR 475
Cdd:PRK11049 397 RKQRPHLHEKSIYKMPLGKLMCWVCMAFFAFVLVLLTLEDDTRQALIVTPLWFIALGLGYLFIGKKRAAELR 468
AnsP COG1113
L-asparagine transporter or related permease [Amino acid transport and metabolism];
12-471 0e+00

L-asparagine transporter or related permease [Amino acid transport and metabolism];


Pssm-ID: 440730 [Multi-domain]  Cd Length: 458  Bit Score: 603.65  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  12 TPTEGPTEEPQLQRGLKNRHLQLIAIGGAIGTGLFLGSGKTISLAGPSILLVYLIIGAVLFFVMRAMGELLLSNLAYKSF 91
Cdd:COG1113    2 STSAAASEEEGLKRGLKNRHIQMIALGGAIGTGLFLGSGKAIALAGPAVLLSYLIAGLIVFLVMRALGEMAVANPVSGSF 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  92 ADFATDLVGPGAGFYMGWTYWMCWVVIGNADTIAMCGYLAAWFPHLDKWIPATCIVLLLTCLNMVAVKLFGEMEFWFAMI 171
Cdd:COG1113   82 SDYAREYLGPWAGFVTGWLYWFFWVLVGMAEATAVGIYLQFWFPDVPQWVWALVFLVLLTAINLLSVKLFGEFEFWFALI 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 172 KIVTIIALILVGGYLAITGFQPPrsGVPAASFSHLWDRGGFFPTGFMGFIAGFQIAIFSFQGIEMAGTAAAETADPEHNL 251
Cdd:COG1113  162 KVVAIVAFIVVGLLLIFFGFGLP--GGPPAGLSNLWDHGGFFPNGIGGVLAALQIVVFAFGGIELVGIAAAEAKDPEKTI 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 252 PKAINSIPARVLIFYVLTLGVIMAVQPWDLINPQASPFVEMFSFIGILIAFHIVNFVVLTSAASSANSGVFSTSRILYGL 331
Cdd:COG1113  240 PKAINSVIWRILLFYVGSLFVILALVPWNQIGAGGSPFVTVFSLLGIPAAAGIMNFVVLTAALSSLNSGLYSTSRMLYSL 319
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 332 AREKDAPPVFAKLSSRHIPRNALILTAMCIAPAIVLVTLEDSvmDAFSLVAGVSSVLYLSVWGLILVCYLKYLGKHPQRH 411
Cdd:COG1113  320 AERGDAPKFFGKLSKRGVPVRAILLSAVVLLIGVVLNYLLPE--KAFTFLLSISGFGALFVWLMILVSQLKFRRRLPREG 397
                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 314927087 412 AE-SAFKMPAGRVMSWVGILFFITILIMLGFSADSRQALIAAPVWVIFMMVLYRLLASARA 471
Cdd:COG1113  398 AAaLKFKMPGFPYTSYLTLAFLAAVLVLMAFDPDTRIALIVGPVWLALLVVGYFLVRRRRA 458
GABAperm TIGR01773
gamma-aminobutyrate permease; GABA permease (gabP) catalyzes the translocation of ...
22-467 9.40e-92

gamma-aminobutyrate permease; GABA permease (gabP) catalyzes the translocation of 4-aminobutyrate (GABA) across the plasma membrane, with homologues expressed in Gram-negative and Gram-positive organisms. This permease is a highly hydrophobic transmembrane protein consisting of 12 transmembrane domains with hydrophilic N- and C-terminal ends. Induced by nitrogen-limited culture conditions in both Escherichia coli and Bacillus subtilis, gabP is an energy dependent transport system stimulated by membrane potential and has been observed adjacent and distant from other GABA degradation proteins. GabP is highly homologous to amino acid permeases from B. subtilis, E. coli, as well as to other members of the amino acid permease family (pfam00324). A member of the APC (amine-polyamine-choline) transporter superfamily, GABA permease possesses a "consensus amphiphatic region" (CAR) found to be evolutionarily conserved within this transport family. This amphiphatic region is located between helix 8 and cytoplasmic loop 8-9, forming a potential channel domain and suggested to play a significant role in ligand recognition and translocation. Unique to GABA permeases, a conserved cysteine residue (CYS-300, E.coli) located at the beginning of the amphiphatic domain, has been determined to be critical for catalytic specificity. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273797  Cd Length: 452  Bit Score: 286.77  E-value: 9.40e-92
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087   22 QLQRGLKNRHLQLIAIGGAIGTGLFLGSGKTISLAGPSILLVYLIIGAVLFFVMRAMGELLLSNLAYKSFADFATDLVGP 101
Cdd:TIGR01773   9 KLPNGLKTRHVTMLSIAGVIGAGLFVGSGSAIASAGPAALLAYLLAGLLVVFIMRMLGEMAVANPDTGSFSTYADDAIGR 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  102 GAGFYMGWTYWMCWVVIGNADTIAMCGYLAAWFPHLDKWIPATCIVLLLTCLNMVAVKLFGEMEFWFAMIKIVTIIALIL 181
Cdd:TIGR01773  89 WAGFTIGWLYWWFWVLVIPLEAIAAAGILQYWFPDIPLWLFSLILTIVLTLTNLYSVKSYGEFEFWFALIKVIAIIAFII 168
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  182 VgGYLAITGFQPPRSgvpAASFSHLWDRGGFFPTGFMGFIAGFQIAIFSFQGIEMAGTAAAETADPEHNLPKAINSIPAR 261
Cdd:TIGR01773 169 L-GAVAIFGFAPGSE---VSGFSNLTGKGGFFPNGIGAVLLAILVTMFSFMGTEIVTIAAAESSNPIKSITRATNSVIWR 244
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  262 VLIFYVLTLGVIMAVQPWDLIN-PQASPFVEMFSFIGILIAFHIVNFVVLTSAASSANSGVFSTSRILYGLAREKDAPPV 340
Cdd:TIGR01773 245 IIVFYLGSIFIVVALLPWNSPNlLEVGSYVAVLELLGIPHAKLIMDFVVLTAVLSCLNSALYTTSRMLYSLAERGDAPRV 324
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  341 FAKLSSRHIPRNALIL-TAMCIAPAIVLVTLEDSVmdaFSLVAGVSSVLYLSVWGLILVCYLKYLGKHPQRHAESAFKMP 419
Cdd:TIGR01773 325 FMKLNKKGVPVQAVLAsTFFSFLTVVVNYFAPDKV---FLFLVNSSGAIALLVYLVIAVSQLRMRKKLKANGEAIKIRMW 401
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*...
gi 314927087  420 AGRVMSWVGILFFITILIMLGFSADSRQALIAAPVWVIFMMVLYRLLA 467
Cdd:TIGR01773 402 LYPWLTWLVIIFICGILVSMLFIPSMRDEVLLTGLLTIIVLCSYLVFA 449
AA_permease pfam00324
Amino acid permease;
31-443 1.38e-91

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 286.91  E-value: 1.38e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087   31 HLQLIAIGGAIGTGLFLGSGKTISLAGP-SILLVYLIIGAVLFFVMRAMGELLLSNLAYKSFADFATDLVGPGAGFYMGW 109
Cdd:pfam00324   1 HVQMIALGGVIGTGLFVGSGSVLGQAGPaGALLGYLISGVVIFLVMLSLGEISTNGPVSGGFYTYASRFLGPSLGFATGW 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  110 TYWMCWVVIGNADTIAMCGYLAAWFPHLD---KWIPATCIVLLLTCLNMVAVKLFGEMEFWFAMIKIVTIIALILVGgyl 186
Cdd:pfam00324  81 NYWLSWITVLALELTAASILIQFWELVPDipyLWVWGAVFLVLLTIINLVGVKWYGEAEFWFALIKIIAIIGFIIVG--- 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  187 AITGFQPPRSgvPAASFSHLWDRGG--FFPTGFM-GFIAGFQIAIFSFQGIEMAGTAAAETADPEHNLPKAINSIPARVL 263
Cdd:pfam00324 158 IILLSGGNPN--DGAIFRYLGDNGGknNFPPGFGkGFISVFVIAFFAFTGIELVGIAAGEVKNPEKSIPKAILQVIWRIT 235
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  264 IFYVLTLGVIMAVQPWD------LINPQASPFVEMFSFIGILIAFHIVNFVVLTSAASSANSGVFSTSRILYGLAREKDA 337
Cdd:pfam00324 236 IFYILSLLAIGLLVPWNdpgllnDSASAASPFVIFFKFLGISGLAPLINAVILTAALSAANSSLYSGSRMLYSLARDGLA 315
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  338 PPVFAKLSSRHIPRNALILTamCIAPAIVLVTLEDSVMDAFSLVAGVSSVLYLSVWGLILVCYLKY---LGKHPQRHAES 414
Cdd:pfam00324 316 PKFLKKVDKRGVPLRAILVS--MVISLLALLLASLNPAIVFNFLLAISGLSGLIVWGLISLSHLRFrkaFKYQGRSIDEL 393
                         410       420
                  ....*....|....*....|....*....
gi 314927087  415 AFKMPAGRVMSWVGILFFITILIMLGFSA 443
Cdd:pfam00324 394 PFKAPLGPLGVILGLAAIIIILIIQFLYA 422
 
Name Accession Description Interval E-value
PRK11049 PRK11049
D-alanine/D-serine/glycine permease; Provisional
4-475 0e+00

D-alanine/D-serine/glycine permease; Provisional


Pssm-ID: 236830  Cd Length: 469  Bit Score: 619.44  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087   4 MDSATQATTPTegPTEEPQLQRGLKNRHLQLIAIGGAIGTGLFLGSGKTISLAGPSILLVYLIIGAVLFFVMRAMGELLL 83
Cdd:PRK11049   1 VDQVKVVADDQ--APAEQSLRRNLTNRHIQLIAIGGAIGTGLFMGSGKTISLAGPSIIFVYMIIGFMLFFVMRAMGELLL 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  84 SNLAYKSFADFATDLVGPGAGFYMGWTYWMCWVVIGNADTIAMCGYLAAWFPHLDKWIPATCIVLLLTCLNMVAVKLFGE 163
Cdd:PRK11049  79 SNLEYKSFSDFASDLLGPWAGYFTGWTYWFCWVVTGIADVVAITAYAQFWFPDLSDWVASLAVVLLLLSLNLATVKMFGE 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 164 MEFWFAMIKIVTIIALILVGGYLAITGFQPPrSGVpAASFSHLWDRGGFFPTGFMGFIAGFQIAIFSFQGIEMAGTAAAE 243
Cdd:PRK11049 159 MEFWFAMIKIVAIVALIVVGLVMVAMHFQSP-TGV-EASFAHLWNDGGMFPKGLSGFFAGFQIAVFAFVGIELVGTTAAE 236
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 244 TADPEHNLPKAINSIPARVLIFYVLTLGVIMAVQPWDLINPQASPFVEMFSFIGILIAFHIVNFVVLTSAASSANSGVFS 323
Cdd:PRK11049 237 TKDPEKSLPRAINSIPIRIIMFYVFALIVIMSVTPWSSVVPDKSPFVELFVLVGLPAAASVINFVVLTSAASSANSGVFS 316
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 324 TSRILYGLAREKDAPPVFAKLSSRHIPRNALILTAMCIAPAIVLVTLEDSVMDAFSLVAGVSSVLYLSVWGLILVCYLKY 403
Cdd:PRK11049 317 TSRMLFGLAQEGVAPKAFAKLSKRAVPAKGLTFSCICLLGGVVLLYVNPSVIGAFTLVTTVSAILFMFVWTIILCSYLVY 396
                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 314927087 404 LGKHPQRHAESAFKMPAGRVMSWVGILFFITILIMLGFSADSRQALIAAPVWVIFMMVLYRLLASARADHTR 475
Cdd:PRK11049 397 RKQRPHLHEKSIYKMPLGKLMCWVCMAFFAFVLVLLTLEDDTRQALIVTPLWFIALGLGYLFIGKKRAAELR 468
AnsP COG1113
L-asparagine transporter or related permease [Amino acid transport and metabolism];
12-471 0e+00

L-asparagine transporter or related permease [Amino acid transport and metabolism];


Pssm-ID: 440730 [Multi-domain]  Cd Length: 458  Bit Score: 603.65  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  12 TPTEGPTEEPQLQRGLKNRHLQLIAIGGAIGTGLFLGSGKTISLAGPSILLVYLIIGAVLFFVMRAMGELLLSNLAYKSF 91
Cdd:COG1113    2 STSAAASEEEGLKRGLKNRHIQMIALGGAIGTGLFLGSGKAIALAGPAVLLSYLIAGLIVFLVMRALGEMAVANPVSGSF 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  92 ADFATDLVGPGAGFYMGWTYWMCWVVIGNADTIAMCGYLAAWFPHLDKWIPATCIVLLLTCLNMVAVKLFGEMEFWFAMI 171
Cdd:COG1113   82 SDYAREYLGPWAGFVTGWLYWFFWVLVGMAEATAVGIYLQFWFPDVPQWVWALVFLVLLTAINLLSVKLFGEFEFWFALI 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 172 KIVTIIALILVGGYLAITGFQPPrsGVPAASFSHLWDRGGFFPTGFMGFIAGFQIAIFSFQGIEMAGTAAAETADPEHNL 251
Cdd:COG1113  162 KVVAIVAFIVVGLLLIFFGFGLP--GGPPAGLSNLWDHGGFFPNGIGGVLAALQIVVFAFGGIELVGIAAAEAKDPEKTI 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 252 PKAINSIPARVLIFYVLTLGVIMAVQPWDLINPQASPFVEMFSFIGILIAFHIVNFVVLTSAASSANSGVFSTSRILYGL 331
Cdd:COG1113  240 PKAINSVIWRILLFYVGSLFVILALVPWNQIGAGGSPFVTVFSLLGIPAAAGIMNFVVLTAALSSLNSGLYSTSRMLYSL 319
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 332 AREKDAPPVFAKLSSRHIPRNALILTAMCIAPAIVLVTLEDSvmDAFSLVAGVSSVLYLSVWGLILVCYLKYLGKHPQRH 411
Cdd:COG1113  320 AERGDAPKFFGKLSKRGVPVRAILLSAVVLLIGVVLNYLLPE--KAFTFLLSISGFGALFVWLMILVSQLKFRRRLPREG 397
                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 314927087 412 AE-SAFKMPAGRVMSWVGILFFITILIMLGFSADSRQALIAAPVWVIFMMVLYRLLASARA 471
Cdd:COG1113  398 AAaLKFKMPGFPYTSYLTLAFLAAVLVLMAFDPDTRIALIVGPVWLALLVVGYFLVRRRRA 458
LysP COG0833
Amino acid permease [Amino acid transport and metabolism];
14-465 1.43e-121

Amino acid permease [Amino acid transport and metabolism];


Pssm-ID: 440595 [Multi-domain]  Cd Length: 467  Bit Score: 364.11  E-value: 1.43e-121
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  14 TEGPTEEPQLQRGLKNRHLQLIAIGGAIGTGLFLGSGKTISLAGP-SILLVYLIIGAVLFFVMRAMGELLlsnlAYK--- 89
Cdd:COG0833    1 SSGSEKQNKLKRGLKSRHLSMIALGGVIGTGLFLASGYTISQAGPgGALLAYLLGGLMVYFLMTSLGELA----VAMpvs 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  90 -SFADFATDLVGPGAGFYMGWTYWMCWVVIGNADTIAMCGYLAAWFPHLDKWIPATCIVLLLTCLNMVAVKLFGEMEFWF 168
Cdd:COG0833   77 gSFQTYATRFIDPAFGFAVGWNYWLNWAITVAAELTAAGIIMQYWFPDVPVWIWSLLFLALIFLLNALSVKAFGESEFWF 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 169 AMIKIVTIIALILVGGyLAITGFqpprSGVPAASFSHLWDRGGFFPTGFMGFIAGFQIAIFSFQGIEMAGTAAAETADPE 248
Cdd:COG0833  157 SLIKVITVIAFIIVGL-LMIFGI----IGGHAPGFSNFTTGDGPFPGGFLAILGVMMIVGFSFQGTELIGIAAGESENPE 231
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 249 HNLPKAINSIPARVLIFYVLTLGVIMAVQPWDLINPQASPFVEMFSFIGILIAFHIVNFVVLTSAASSANSGVFSTSRIL 328
Cdd:COG0833  232 KTIPKAIRQVFWRILLFYILAIFVIAALIPYTDAGVAESPFTLVFERAGIPYAADIMNAVILTAVLSAGNSGLYASTRML 311
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 329 YGLAREKDAPPVFAKLSSRHIPRNALILTaMCIAPAIVLVTL--EDSVMDAFSLVAGVSSVLylsVWGLILVCYLKY--- 403
Cdd:COG0833  312 WSLAKEGMAPKIFAKLNKRGVPLNALLAT-MAVGLLALLSSFfgAGTVYLWLLSISGLTGFI---AWLGIAISHYRFrra 387
                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 314927087 404 LGKHPQRHAESAFKMPAGRVMSWVGILFFITILIMLGFSADSRQALIAAPVWVIFMMVLYRL 465
Cdd:COG0833  388 YVAQGGDLEDLKYKAPLFPFGPIFAFILCLIVIIGQAFDPEQRIALYIGIPFFLACYLGYKL 449
PRK10238 PRK10238
aromatic amino acid transporter AroP;
15-463 1.78e-107

aromatic amino acid transporter AroP;


Pssm-ID: 182324 [Multi-domain]  Cd Length: 456  Bit Score: 327.68  E-value: 1.78e-107
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  15 EGPTEEPQLQRGLKNRHLQLIAIGGAIGTGLFLGSGKTISLAGPSILLVYLIIGAVLFFVMRAMGELLLSNLAYKSFADF 94
Cdd:PRK10238   2 EGQQHGEQLKRGLKNRHIQLIALGGAIGTGLFLGSASVIQSAGPGIILGYAIAGFIAFLIMRQLGEMVVEEPVAGSFSHF 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  95 ATDLVGPGAGFYMGWTYWMCWVVIGNADTIAMCGYLAAWFPHLDKWIPATCIVLLLTCLNMVAVKLFGEMEFWFAMIKIV 174
Cdd:PRK10238  82 AYKYWGSFAGFASGWNYWVLYVLVAMAELTAVGKYIQFWYPEIPTWVSAAVFFVVINAINLTNVKVFGEMEFWFAIIKVI 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 175 TIIALILVGGYLAITGfqpprSGVPAASFSHLWDRGGFFPTGFMGFIAGFQIAIFSFQGIEMAGTAAAETADPEHNLPKA 254
Cdd:PRK10238 162 AVVAMIIFGGWLLFSG-----NGGPQATVSNLWDQGGFLPHGFTGLVMMMAIIMFSFGGLELVGITAAEADNPEQSIPKA 236
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 255 INSIPARVLIFYVLTLGVIMAVQPWDLINPQASPFVEMFSFIGILIAFHIVNFVVLTSAASSANSGVFSTSRILYGLARE 334
Cdd:PRK10238 237 TNQVIYRILIFYIGSLAVLLSLMPWTRVTADTSPFVLIFHELGDTFVANALNIVVLTAALSVYNSCVYCNSRMLFGLAQQ 316
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 335 KDAPPVFAKLSSRHIPRNALILTAMCIAPAIVLVTLedSVMDAFSLV-AGVSSVLYLSvWGLILVCYLKYLGKHPQRHAE 413
Cdd:PRK10238 317 GNAPKALASVDKRGVPVNTILVSALVTALCVLINYL--APESAFGLLmALVVSALVIN-WAMISLAHMKFRRAKQEQGVV 393
                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|
gi 314927087 414 SAFKMPAGRVMSWVGILFFITILIMLGFSADSRQALIAAPVWVIFMMVLY 463
Cdd:PRK10238 394 TRFPALLYPLGNWICLLFMAAVLVIMLMTPGMAISVYLIPVWLIVLGIGY 443
PRK10249 PRK10249
phenylalanine transporter; Provisional
11-466 1.39e-105

phenylalanine transporter; Provisional


Pssm-ID: 236667  Cd Length: 458  Bit Score: 322.71  E-value: 1.39e-105
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  11 TTPTEGPTEEPQLQRGLKNRHLQLIAIGGAIGTGLFLGSGKTISLAGPSILLVYLIIGAVLFFVMRAMGELLLSNLAYKS 90
Cdd:PRK10249   7 VSEDTASNQEPTLHRGLHNRHIQLIALGGAIGTGLFLGIGPAIQMAGPAVLLGYGVAGIIAFLIMRQLGEMVVEEPVSGS 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  91 FADFATDLVGPGAGFYMGWTYWMCWVVIGNADTIAMCGYLAAWFPHLDKWIPATCIVLLLTCLNMVAVKLFGEMEFWFAM 170
Cdd:PRK10249  87 FAHFAYKYWGPFAGFLSGWNYWVMFVLVGMAELTAAGIYMQYWFPDVPTWIWAAAFFIIINAVNLVNVRLYGETEFWFAL 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 171 IKIVTIIALILVGGYLAITGfqpprSGVPAASFSHLWDRGGFFPTGFMGFIAGFQIAIFSFQGIEMAGTAAAETADPEHN 250
Cdd:PRK10249 167 IKVLAIIGMIGFGLWLLFSG-----HGGEKASIDNLWRYGGFFATGWNGLILSLAVIMFSFGGLELIGITAAEARDPEKS 241
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 251 LPKAINSIPARVLIFYVLTLGVIMAVQPWDLINPQASPFVEMFSFIGILIAFHIVNFVVLTSAASSANSGVFSTSRILYG 330
Cdd:PRK10249 242 IPKAVNQVVYRILLFYIGSLVVLLALYPWVEVKSNSSPFVMIFHNLDSNVVASALNFVILVASLSVYNSGVYSNSRMLFG 321
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 331 LAREKDAPPVFAKLSSRHIPRNALILTAMCIAPAIVLVTLEDSvmDAFSLVAGVSSVLYLSVWGLILVCYLKYLGKHPQR 410
Cdd:PRK10249 322 LSVQGNAPKFLTRVSRRGVPINSLMLSGAITSLVVLINYLLPQ--KAFGLLMALVVATLLLNWIMICLAHLRFRAAMRRQ 399
                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 314927087 411 HAESAFKMPAGRVMSWVGILFFITILIMLGFSADSRQALIAAPVWVIFMMVLYRLL 466
Cdd:PRK10249 400 GRETQFKALLYPFGNYLCIAFLGMILLLMCTMDDMRLSAILLPVWIVFLFVAFKTL 455
proY PRK10580
putative proline-specific permease; Provisional
19-465 1.84e-101

putative proline-specific permease; Provisional


Pssm-ID: 182566 [Multi-domain]  Cd Length: 457  Bit Score: 312.14  E-value: 1.84e-101
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  19 EEPQLQRGLKNRHLQLIAIGGAIGTGLFLGSGKTISLAGPSILLVYLIIGAVLFFVMRAMGELLLSNLAYKSFADFATDL 98
Cdd:PRK10580   3 SKNKLKRGLSTRHIRFMALGSAIGTGLFYGSADAIKMAGPSVLLAYIIGGVAAYIIMRALGEMSVHNPAASSFSRYAQEN 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  99 VGPGAGFYMGWTYWMCWVVIGNADTIAMCGYLAAWFPHLDKWIPATCIVLLLTCLNMVAVKLFGEMEFWFAMIKIVTIIA 178
Cdd:PRK10580  83 LGPLAGYITGWTYCFEILIVAIADVTAFGIYMGVWFPTVPHWIWVLSVVLIICAVNLMSVKVFGELEFWFSFFKVATIII 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 179 LILVGGYLAITGFQpprSGVPAASFSHLWDRGGFFPTGFMGFIAGFQIAIFSFQGIEMAGTAAAETADPEHNLPKAINSI 258
Cdd:PRK10580 163 MIVAGIGIIIWGIG---NGGQPTGIHNLWSNGGFFSNGWLGMVMSLQMVMFAYGGIEIIGITAGEAKDPEKSIPRAINSV 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 259 PARVLIFYVLTLGVIMAVQPWDLINPQASPFVEMFSFIGILIAFHIVNFVVLTSAASSANSGVFSTSRILYGLAREKDAP 338
Cdd:PRK10580 240 PMRILVFYVGTLFVIMSIYPWNQVGTNGSPFVLTFQHMGITFAASILNFVVLTASLSAINSDVFGVGRMLHGMAEQGSAP 319
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 339 PVFAKLSSRHIPRNALILTAMCIAPAIVLVTLEDSvmDAFSLVAGVSSVLYLSVWGLILVCYLKYLGKHPQRHAES-AFK 417
Cdd:PRK10580 320 KIFSKTSRRGIPWVTVLVMTTALLFAVYLNYIMPE--NVFLVIASLATFATVWVWIMILLSQIAFRRRLPPEEVKAlKFK 397
                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*...
gi 314927087 418 MPAGRVMSWVGILFFITILIMLGFSADSRQALIAAPVWVIFMMVLYRL 465
Cdd:PRK10580 398 VPGGVATTIGGLIFLVFIIGLIGYHPDTRISLYVGFAWIVLLLIGWMF 445
PRK10746 PRK10746
putative transport protein YifK; Provisional
20-475 1.49e-95

putative transport protein YifK; Provisional


Pssm-ID: 182694  Cd Length: 461  Bit Score: 297.11  E-value: 1.49e-95
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  20 EPQLQRGLKNRHLQLIAIGGAIGTGLFLGSGKTISLAGPSILLVYLIIGAVLFFVMRAMGELLLSNLAYKSFADFATDLV 99
Cdd:PRK10746   5 KPELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPSVLLAYIIAGLFVFFIMRSMGEMLFLEPVTGSFAVYAHRYM 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 100 GPGAGFYMGWTYWMCWVVIGNADTIAMCGYLAAWFPHLDKWIPATCIVLLLTCLNMVAVKLFGEMEFWFAMIKIVTIIAL 179
Cdd:PRK10746  85 SPFFGYLTAWSYWFMWMAVGISEITAIGVYVQFWFPEMAQWIPALIAVALVALANLAAVRLYGEIEFWFAMIKVTTIIVM 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 180 ILVGGYLAITGFQpprSGVPAASFSHLWDRGGFFPTGFMGFIAGFQIAIFSFQGIEMAGTAAAETADPEHNLPKAINSIP 259
Cdd:PRK10746 165 IVIGLGVIFFGFG---NGGQSIGFSNLTEHGGFFAGGWKGFLTALCIVVASYQGVELIGITAGEAKNPQVTLRSAVGKVL 241
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 260 ARVLIFYVLTLGVIMAVQPWDLINPQASPFVEMFSFIGILIAFHIVNFVVLTSAASSANSGVFSTSRILYGLAREKDAPP 339
Cdd:PRK10746 242 WRILIFYVGAIFVIVTIFPWNEIGSNGSPFVLTFAKIGITAAAGIINFVVLTAALSGCNSGMYSCGRMLYALAKNRQLPA 321
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 340 VFAKLSSRHIPRNALILTAMCIAPAIVLVTLEDSVMDAFSLVAGVSSVLYLSVWGLILVCYLKYLGKHPQRHAESAFKMP 419
Cdd:PRK10746 322 AMAKVSRHGVPVAGVAVSILILLVGSCLNYIIPNPQRVFVYVYSASVLPGMVPWFVILISQLRFRRAHKAAIASHPFRSI 401
                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 314927087 420 AGRVMSWVGILFFITILIMLGFSADSRQALIAAPVWVIFMMVLYRLLASARADHTR 475
Cdd:PRK10746 402 LFPWANYLTMAFLICVLIGMYFNEDTRMSLFVGIIFLLAVTLIYKVFGLNRHGKAH 457
GABAperm TIGR01773
gamma-aminobutyrate permease; GABA permease (gabP) catalyzes the translocation of ...
22-467 9.40e-92

gamma-aminobutyrate permease; GABA permease (gabP) catalyzes the translocation of 4-aminobutyrate (GABA) across the plasma membrane, with homologues expressed in Gram-negative and Gram-positive organisms. This permease is a highly hydrophobic transmembrane protein consisting of 12 transmembrane domains with hydrophilic N- and C-terminal ends. Induced by nitrogen-limited culture conditions in both Escherichia coli and Bacillus subtilis, gabP is an energy dependent transport system stimulated by membrane potential and has been observed adjacent and distant from other GABA degradation proteins. GabP is highly homologous to amino acid permeases from B. subtilis, E. coli, as well as to other members of the amino acid permease family (pfam00324). A member of the APC (amine-polyamine-choline) transporter superfamily, GABA permease possesses a "consensus amphiphatic region" (CAR) found to be evolutionarily conserved within this transport family. This amphiphatic region is located between helix 8 and cytoplasmic loop 8-9, forming a potential channel domain and suggested to play a significant role in ligand recognition and translocation. Unique to GABA permeases, a conserved cysteine residue (CYS-300, E.coli) located at the beginning of the amphiphatic domain, has been determined to be critical for catalytic specificity. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273797  Cd Length: 452  Bit Score: 286.77  E-value: 9.40e-92
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087   22 QLQRGLKNRHLQLIAIGGAIGTGLFLGSGKTISLAGPSILLVYLIIGAVLFFVMRAMGELLLSNLAYKSFADFATDLVGP 101
Cdd:TIGR01773   9 KLPNGLKTRHVTMLSIAGVIGAGLFVGSGSAIASAGPAALLAYLLAGLLVVFIMRMLGEMAVANPDTGSFSTYADDAIGR 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  102 GAGFYMGWTYWMCWVVIGNADTIAMCGYLAAWFPHLDKWIPATCIVLLLTCLNMVAVKLFGEMEFWFAMIKIVTIIALIL 181
Cdd:TIGR01773  89 WAGFTIGWLYWWFWVLVIPLEAIAAAGILQYWFPDIPLWLFSLILTIVLTLTNLYSVKSYGEFEFWFALIKVIAIIAFII 168
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  182 VgGYLAITGFQPPRSgvpAASFSHLWDRGGFFPTGFMGFIAGFQIAIFSFQGIEMAGTAAAETADPEHNLPKAINSIPAR 261
Cdd:TIGR01773 169 L-GAVAIFGFAPGSE---VSGFSNLTGKGGFFPNGIGAVLLAILVTMFSFMGTEIVTIAAAESSNPIKSITRATNSVIWR 244
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  262 VLIFYVLTLGVIMAVQPWDLIN-PQASPFVEMFSFIGILIAFHIVNFVVLTSAASSANSGVFSTSRILYGLAREKDAPPV 340
Cdd:TIGR01773 245 IIVFYLGSIFIVVALLPWNSPNlLEVGSYVAVLELLGIPHAKLIMDFVVLTAVLSCLNSALYTTSRMLYSLAERGDAPRV 324
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  341 FAKLSSRHIPRNALIL-TAMCIAPAIVLVTLEDSVmdaFSLVAGVSSVLYLSVWGLILVCYLKYLGKHPQRHAESAFKMP 419
Cdd:TIGR01773 325 FMKLNKKGVPVQAVLAsTFFSFLTVVVNYFAPDKV---FLFLVNSSGAIALLVYLVIAVSQLRMRKKLKANGEAIKIRMW 401
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*...
gi 314927087  420 AGRVMSWVGILFFITILIMLGFSADSRQALIAAPVWVIFMMVLYRLLA 467
Cdd:TIGR01773 402 LYPWLTWLVIIFICGILVSMLFIPSMRDEVLLTGLLTIIVLCSYLVFA 449
AA_permease pfam00324
Amino acid permease;
31-443 1.38e-91

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 286.91  E-value: 1.38e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087   31 HLQLIAIGGAIGTGLFLGSGKTISLAGP-SILLVYLIIGAVLFFVMRAMGELLLSNLAYKSFADFATDLVGPGAGFYMGW 109
Cdd:pfam00324   1 HVQMIALGGVIGTGLFVGSGSVLGQAGPaGALLGYLISGVVIFLVMLSLGEISTNGPVSGGFYTYASRFLGPSLGFATGW 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  110 TYWMCWVVIGNADTIAMCGYLAAWFPHLD---KWIPATCIVLLLTCLNMVAVKLFGEMEFWFAMIKIVTIIALILVGgyl 186
Cdd:pfam00324  81 NYWLSWITVLALELTAASILIQFWELVPDipyLWVWGAVFLVLLTIINLVGVKWYGEAEFWFALIKIIAIIGFIIVG--- 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  187 AITGFQPPRSgvPAASFSHLWDRGG--FFPTGFM-GFIAGFQIAIFSFQGIEMAGTAAAETADPEHNLPKAINSIPARVL 263
Cdd:pfam00324 158 IILLSGGNPN--DGAIFRYLGDNGGknNFPPGFGkGFISVFVIAFFAFTGIELVGIAAGEVKNPEKSIPKAILQVIWRIT 235
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  264 IFYVLTLGVIMAVQPWD------LINPQASPFVEMFSFIGILIAFHIVNFVVLTSAASSANSGVFSTSRILYGLAREKDA 337
Cdd:pfam00324 236 IFYILSLLAIGLLVPWNdpgllnDSASAASPFVIFFKFLGISGLAPLINAVILTAALSAANSSLYSGSRMLYSLARDGLA 315
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  338 PPVFAKLSSRHIPRNALILTamCIAPAIVLVTLEDSVMDAFSLVAGVSSVLYLSVWGLILVCYLKY---LGKHPQRHAES 414
Cdd:pfam00324 316 PKFLKKVDKRGVPLRAILVS--MVISLLALLLASLNPAIVFNFLLAISGLSGLIVWGLISLSHLRFrkaFKYQGRSIDEL 393
                         410       420
                  ....*....|....*....|....*....
gi 314927087  415 AFKMPAGRVMSWVGILFFITILIMLGFSA 443
Cdd:pfam00324 394 PFKAPLGPLGVILGLAAIIIILIIQFLYA 422
PRK15049 PRK15049
L-asparagine permease;
20-461 3.08e-82

L-asparagine permease;


Pssm-ID: 185009  Cd Length: 499  Bit Score: 263.79  E-value: 3.08e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  20 EPQLQRGLKNRHLQLIAIGGAIGTGLFLGSGKTISLAGPSILLVYLIIGAVLFFVMRAMGELLLSNLAYKSFADFATDLV 99
Cdd:PRK15049  23 EEGYHKAMGNRQVQMIAIGGAIGTGLFLGAGARLQMAGPALALVYLICGLFSFFILRALGELVLHRPSSGSFVSYAREFL 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 100 GPGAGFYMGWTYWMCWVVIGNADTIAMCGYLAAW--FPHLDKWIPATCIVLLLTCLNMVAVKLFGEMEFWFAMIKIVTII 177
Cdd:PRK15049 103 GEKAAYVAGWMYFINWAMTGIVDITAVALYMHYWgaFGGVPQWVFALAALTIVGTMNMIGVKWFAEMEFWFALIKVLAIV 182
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 178 ALILVGGYLAITGfqPPRSGvPAASFSHLWDRGGFFPTGFMGFIAGFQIAIFSFQGIEMAGTAAAETADPEHNLPKAINS 257
Cdd:PRK15049 183 TFLVVGTVFLGSG--QPLDG-NTTGFHLITDNGGFFPHGLLPALVLIQGVVFAFASIEMVGTAAGECKDPQTMVPKAINS 259
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 258 IPARVLIFYVLTLGVIMAVQPWDLINPQASPFVEMFSFIGILIAFHIVNFVVLTSAASSANSGVFSTSRILYGLAREKDA 337
Cdd:PRK15049 260 VIWRIGLFYVGSVVLLVMLLPWSAYQAGQSPFVTFFSKLGVPYIGSIMNIVVLTAALSSLNSGLYCTGRILRSMAMGGSA 339
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 338 PPVFAKLSSRHIPRNALILTAMCIAPAIVLVTLEDSvmDAFSLVAGVSSVLYLSVWGLILVCYLKYLGKHPQ-RHAESAF 416
Cdd:PRK15049 340 PSFMAKMSRQHVPYAGILATLVVYVVGVFLNYLVPS--RVFEIVLNFASLGIIASWAFIIVCQMRLRKAIKEgKAADVSF 417
                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*
gi 314927087 417 KMPAGRVMSWVGILFFITILIMLGFSADSRQALIAAPVWVIFMMV 461
Cdd:PRK15049 418 KLPGAPFTSWLTLLFLLSVLVLMAFDYPNGTYTIAALPIIGILLV 462
PRK10836 PRK10836
lysine transporter; Provisional
18-357 3.47e-77

lysine transporter; Provisional


Pssm-ID: 182767  Cd Length: 489  Bit Score: 250.12  E-value: 3.47e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  18 TEEPQLQRGLKNRHLQLIAIGGAIGTGLFLGSGKTISLAGPS-ILLVYLIIGAVLFFVMRAMGELLLSNLAYKSFADFAT 96
Cdd:PRK10836   8 TEAPGLRRELKARHLTMIAIGGSIGTGLFVASGATISQAGPGgALLSYMLIGLMVYFLMTSLGELAAYMPVSGSFATYGQ 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  97 DLVGPGAGFYMGWTYWMCWVVIGNADTIAMCGYLAAWFPHLDKWIPATCIVLLLTCLNMVAVKLFGEMEFWFAMIKIVTI 176
Cdd:PRK10836  88 NYVEEGFGFALGWNYWYNWAVTIAVDLVAAQLVMSWWFPDTPGWIWSALFLGVIFLLNYISVRGFGEAEYWFSLIKVTTV 167
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 177 IALILVgGYLAITGFQppRSGVPAAsfSHLWDRG-GFFPTGFMGFIAGFQIAIFSFQGIEMAGTAAAETADPEHNLPKAI 255
Cdd:PRK10836 168 IVFIIV-GVLMIIGIF--KGAEPAG--WSNWTIGdAPFAGGFAAMIGVAMIVGFSFQGTELIGIAAGESEDPAKNIPRAV 242
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 256 NSIPARVLIFYVLTLGVIMAVQPW--------DLINPQASPFVEMFSFIGILIAFHIVNFVVLTSAASSANSGVFSTSRI 327
Cdd:PRK10836 243 RQVFWRILLFYVFAILIISLIIPYtdpsllrnDVKDISVSPFTLVFQHAGLLSAAAVMNAVILTAVLSAGNSGMYASTRM 322
                        330       340       350
                 ....*....|....*....|....*....|
gi 314927087 328 LYGLAREKDAPPVFAKLSSRHIPRNALILT 357
Cdd:PRK10836 323 LYTLACDGKAPRIFAKLSRGGVPRNALYAT 352
2A0310 TIGR00913
amino acid permease (yeast); [Transport and binding proteins, Amino acids, peptides and amines]
24-463 1.72e-76

amino acid permease (yeast); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273334  Cd Length: 478  Bit Score: 247.97  E-value: 1.72e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087   24 QRGLKNRHLQLIAIGGAIGTGLFLGSGKTISLAGP-SILLVYLIIGAVLFFVMRAMGEL-LLSNLAYKSFADFATDLVGP 101
Cdd:TIGR00913   1 KKSLKQRHIQMIALGGTIGTGLLVGSGTALATGGPaGLLIGYAIMGSIIYCVMQSLGEMaTFYPVVSGSFATYASRFVDP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  102 GAGFYMGWTYWMCWVVIGNADTIAMCGYLAAWFPHLDKWIPATCIVLLLTCLNMVAVKLFGEMEFWFAMIKIVTIIALIL 181
Cdd:TIGR00913  81 AFGFAVGWNYWLQWLIVLPLELVTASMTIQYWTDKVNPAVWIAIFYVFIVIINLFGVKGYGEAEFWFSSIKILAIIGFII 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  182 VGGYLaITGFQPPRSGVPAasfsHLWD-----RGGFFPTGFMGFIAGFQIAIFSFQGIEMAGTAAAETADPEHNLPKAIN 256
Cdd:TIGR00913 161 LSIIL-NCGGGPNHGYIGF----RYWHdpgafAGGTIGGRFKGVCSVFVTAAFSFGGTELVALTAGEAANPRKSIPRAAK 235
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  257 SIPARVLIFYVLTLGVIMAVQPWD---------LINPQASPFVEMFSFIGILIAFHIVNFVVLTSAASSANSGVFSTSRI 327
Cdd:TIGR00913 236 RTFWRILVFYILTLFLIGFLVPYNdprllssssSSDSAASPFVIAIQNHGIKVLPHIFNAVILISVLSAANSSLYASSRT 315
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  328 LYGLAREKDAPPVFAKLSSRHIPRNALILTAMCIAPAIVLVTleDSVMDAFSLVAGVSSVLYLSVWGLILVCYLKY---L 404
Cdd:TIGR00913 316 LYALAHQGLAPKIFAYVDRRGVPYVAVIVSSLFGLLAFLAVS--KKEAEVFTWLLNISGLSGFFTWMCICLSHIRFrkaM 393
                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 314927087  405 GKHPQRHAESAFKMPAGRVMSWVGILFFITILIMLGFSA-----DSRQALIAAPVWVIFMMVLY 463
Cdd:TIGR00913 394 KAQGRSLDELPYKSQTGPYGSYYALFFNILILIAQGYVAfapvkFSAKSFFEAYLSLPIFIALY 457
PRK11387 PRK11387
S-methylmethionine permease;
13-449 2.56e-69

S-methylmethionine permease;


Pssm-ID: 236904  Cd Length: 471  Bit Score: 228.97  E-value: 2.56e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  13 PTEGPTEEPQLQRGLKNRHLQLIAIGGAIGTGLFLGSGKTISLAGPS-ILLVYLIIGAVLFFVMRAMGELLLSNLAYKSF 91
Cdd:PRK11387   2 PEPTSQQAGQFKRTMKVRHLVMLSLGGVIGTGLFFNTGYIISTTGAAgTLLAYLIGALVVYLVMQCLGELSVAMPETGAF 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  92 ADFATDLVGPGAGFYMGWTYWMCWVVIGNADTIAMCGYLAAWFPHLDKWIPATCIVLLLTCLNMVAVKLFGEMEFWFAMI 171
Cdd:PRK11387  82 HVYAARYLGPATGYTVAWLYWLTWTVALGSSLTAAGFCMQYWFPQVPVWPWCLLFCALIFGLNVVSTRFFAEGEFWFSLI 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 172 KIVTIIALILVGGyLAITGFQPPRSGVPAASFSHLwDRGGFFPTGFMGFIAGFQIAIFSFQGIEMAGTAAAETADPEHNL 251
Cdd:PRK11387 162 KVVTILAFIVLGG-AAIFGFIPMQDGSPAPGLRNL-TAEGWFPHGGLPILMTMVAVNFAFSGTELIGIAAGETENPAKVI 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 252 PKAINSIPARVLIFYVLTLGVIMAVQPWDLINPQASPFVEMFSFIGILIAFHIVNFVVLTSAASSANSGVFSTSRILYGL 331
Cdd:PRK11387 240 PVAIRTTIARLVIFFVGTVLVLAALIPMQQAGVEKSPFVLVFEKVGIPYAADIFNFVILTAILSAANSGLYASGRMLWSL 319
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 332 AREKDAPPVFAKLSSRHIPRNALILTAMCIAPAIVL-VTLEDSVMDAFSLVAGVSSVlylSVWGLILVCYLKYLGKHPQR 410
Cdd:PRK11387 320 SNEGTLPACFARLTKRGIPLTALSVSMLGGLLALFSsVVAPDTVFVALSAISGFAVV---AVWLSICASHFMFRRRHLRD 396
                        410       420       430       440
                 ....*....|....*....|....*....|....*....|..
gi 314927087 411 H---AESAFKMPAGRVMSWVGILFFITILIMLGFSADSRQAL 449
Cdd:PRK11387 397 GkalSELAYRAPWYPLTPILGFVLCLLACVGLAFDPSQRIAL 438
PRK10197 PRK10197
GABA permease;
34-451 3.75e-57

GABA permease;


Pssm-ID: 182297  Cd Length: 446  Bit Score: 196.38  E-value: 3.75e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  34 LIAIGGAIGTGLFLGSGKTISLAGPSILLVYLIIGAVLFFVMRAMGELLLSNLAYKSFADFATDLVGPGAGFYMGWTYWM 113
Cdd:PRK10197   1 MLSIAGVIGASLFVGSSVAIAEAGPAVLLAYLFAGLLVVMIMRMLAEMAVATPDTGSFSTYADKAIGRWAGYTIGWLYWW 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 114 CWVVIGNADTIAMCGYLAAWFPHLDKWIPATCIVLLLTCLNMVAVKLFGEMEFWFAMIKIVTIIALILVGGyLAITGFQP 193
Cdd:PRK10197  81 FWVLVIPLEANIAAMILHSWVPGIPIWLFSLVITLALTGSNLLSVKNYGEFEFWLALCKVIAILAFIFLGA-VAISGFYP 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 194 PrsgVPAASFSHLWDRGGFFPTGFMGFIAGFQIAIFSFQGIEMAGTAAAETADPEHNLPKAINSIPARVLIFYVLTLGVI 273
Cdd:PRK10197 160 Y---AEVSGISRLWDSGGFMPNGFGAVLSAMLITMFSFMGAEIVTIAAAESDTPEKHIVRATNSVIWRISIFYLCSIFVV 236
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 274 MAVQPWDLINPQA-SPFVEMFSFIGILIAFHIVNFVVLTSAASSANSGVFSTSRILYGLAREKDAPPVFAKLSSRHIPRN 352
Cdd:PRK10197 237 VALIPWNMPGLKAvGSYRSVLELLNIPHAKLIMDCVILLSVTSCLNSALYTASRMLYSLSRRGDAPAVMGKINRSKTPYV 316
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 353 ALILTAMciAPAIVLVTLEDSVMDAFSLVAGVSSVLYLSVWGLILVCYLKYLGKHPQRHAESAFKMPAGRVMSWVGILFF 432
Cdd:PRK10197 317 AVLLSTG--AAFLTVVVNYYAPAKVFKFLIDSSGAIALLVYLVIAVSQLRMRKILRAEGSEIRLRMWLYPWLTWLVIGFI 394
                        410
                 ....*....|....*....
gi 314927087 433 ITILIMLGFSADSRQALIA 451
Cdd:PRK10197 395 TFVLVVMLFRPAQQLEVIS 413
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
18-475 4.43e-52

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 182.40  E-value: 4.43e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  18 TEEPQLQRGLKNRHLQLIAIGGAIGTGLFLGSGKTISLAGPSILLVYLIIGAVLFFVMRAMGELllsNLAYK---SFADF 94
Cdd:COG0531    4 GESSELKRKLGLFDLVALGVGAIIGAGIFVLPGLAAGLAGPAAILAWLIAGLLALLVALSYAEL---ASAFPragGAYTY 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  95 ATDLVGPGAGFYMGWTYWMCWVVIGNADTIAMCGYLAAWFPHLDKWIPATCIVLLLTCLNMVAVKLFGEMEFWFAMIKIV 174
Cdd:COG0531   81 ARRALGPLLGFLAGWALLLSYVLAVAAVAVAFGGYLSSLFPAGGSVLIALVLILLLTLLNLRGVKESAKVNNILTVLKLL 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 175 TIIALILVGGYlaitgfqpprsGVPAASFSHLWDrggfFPTGFMGFIAGFQIAIFSFQGIEMAGTAAAETADPEHNLPKA 254
Cdd:COG0531  161 VLLLFIVVGLF-----------AFDPANFTPFLP----AGGGLSGVLAALALAFFAFTGFEAIANLAEEAKNPKRNIPRA 225
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 255 INSIPARVLIFYVLTLGVIMAVQPWDLINPQASPFVEMFSFIGILIAFHIVNFVVLTSAASSANSGVFSTSRILYGLARE 334
Cdd:COG0531  226 IILSLLIVGVLYILVSLALTGVVPYDELAASGAPLADAAEAVFGPWGAILIALGALLSLLGALNASILGASRLLYAMARD 305
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 335 KDAPPVFAKLSSRH-IPRNALILTAMCIAPAIVLvtledsVMDAFSLVAGVSSVLYLSVWGLILVCYLKYLGKHPqrHAE 413
Cdd:COG0531  306 GLLPKVFAKVHPRFgTPVNAILLTGVIALLLLLL------GAASFTALASLASVGVLLAYLLVALAVIVLRRRRP--DLP 377
                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 314927087 414 SAFKMPaGRVMSWVGILFFITILIMLGFsadsrQALIAAPVWVIFMMVLYRLLASARADHTR 475
Cdd:COG0531  378 RPFRVP-LPLIPILGILLCLFLLYLLGP-----GALLIGLVLLAIGLLLYLLYRRRHPKLLK 433
AA_permease_2 pfam13520
Amino acid permease;
35-462 9.48e-28

Amino acid permease;


Pssm-ID: 404414 [Multi-domain]  Cd Length: 427  Bit Score: 115.10  E-value: 9.48e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087   35 IAIGGAIGTGLFLGSGktISLAGPSILLVYLIIGAVLFFVMRamgeLLLSNLAYKSFAD-----FATDLVGPGAGFYMGW 109
Cdd:pfam13520   9 LVIGSVIGSGIFVAPL--VASGGPALIVWGWIAAIIFSLAVG----LVYAELSSALPRSggiyvYLENAFGKFVAFLAGW 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  110 TYWMCWVVIGNADTIAMCGYLA-AWFPHLDKWIP-----ATCIVLLLTCLNMVAVKLFGEMEFWFAMIKIVTIIALILVG 183
Cdd:pfam13520  83 SNWFAYVLGLASSASVAASYLLsALGPDLVPTTWltygiAIAILIIFAIINIRGVRESAKIQNILGILKLLLPLILIIIL 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  184 GYLAITGFQPPRSGVPAASFshlwdrggfFPTGFMGFIAGFQIAIFSFQGIEMAGTAAAETADPehNLPKAINSIPARVL 263
Cdd:pfam13520 163 GLVTADGGGFNLLSGEWHTF---------FPDGWPGVFAGFLGVLWSFTGFESAANVSEEVKKR--NVPKAIFIGVIIVG 231
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  264 IFYVLTLGVIMAVQPWD---LINPQASPFVEMFSFIGILIAFHIVNFVVLTSAASSANSGVFSTSRILYGLAREKDAP-- 338
Cdd:pfam13520 232 VLYILVNIAFFGVVPDDeiaLSSGLGQVAALLFQAVGGKWGAIIVVILLALSLLGAVNTAIVGASRLLYALARDGVLPfs 311
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  339 PVFAKLSSRHIPRNALILTAMCIAPAIVLVTLEDSVMDAfslVAGVSSVLYLSVWGLILVCYLKYLGKHPQRHaesafKM 418
Cdd:pfam13520 312 RFFAKVNKFGSPIRAIILTAILSLILLLLFLLSPAAYNA---LLSLSAYGYLLSYLLPIIGLLILRKKRPDLG-----RI 383
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....
gi 314927087  419 PAGRVMSWVGILFFITILIMLGFSADSRQALIAAPVWVIFMMVL 462
Cdd:pfam13520 384 PGRWPVAIFGILFSLFLIVALFFPPVGPATGSSLNYAIILIVAF 427
2A0303 TIGR00906
cationic amino acid transport permease; [Transport and binding proteins, Amino acids, peptides ...
19-382 4.92e-20

cationic amino acid transport permease; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273330 [Multi-domain]  Cd Length: 557  Bit Score: 92.96  E-value: 4.92e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087   19 EEPQLQRGLKNRHLQLIAIGGAIGTGLFLGSGKTI-SLAGPSILLVYLIIGAVLffvmramgelLLSNLAYKSFA----- 92
Cdd:TIGR00906  22 EESKMKRCLTTWDLMALGIGSTIGAGIYVLTGEVArNDSGPAIVLSFLISGLAA----------VLSGFCYAEFGarvpk 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087   93 ---DFATDLVGPGA--GFYMGWTYWMCWVVIGNADTIAMCGYLAAWFPH-LDKW-----------------IPATCIVLL 149
Cdd:TIGR00906  92 agsAYLYSYVTVGElwAFITGWNLILEYVIGTAAVARSWSAYFDELLNKqIGQFrrtyfklnydglaeypdFFAVCLILL 171
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  150 LTCLNMVAVKLFGEMEFWFAMIKIVtIIALILVGGYLaitgfqppRSGVPAASFSHLWDRGGFFPTGFMGFIAGFQIAIF 229
Cdd:TIGR00906 172 LAVLLSFGVKESAWVNKIFTAINIL-VLLFVIIAGFT--------KADVANWSITEEKGAGGFMPYGFTGVLSGAATCFF 242
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  230 SFQGIEMAGTAAAETADPEHNLPKAINSIPARVLIFYVLTLGVIMAVQPWDLINPQaSPFVEMFSFIGILIAFHIVNFVV 309
Cdd:TIGR00906 243 AFIGFDAIATTGEEVKNPQRAIPIGIVTSLLVCFVAYFLMSAALTLMMPYYLLDPD-APFPVAFEYVGWDPAKYIVAVGA 321
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  310 LTSAASSANSGVFSTSRILYGLAREKDAPPVFAKLSSR-HIPRNALIlTAMCIAPAIVLVT--------LEDSVMDAFSL 380
Cdd:TIGR00906 322 LCGMSTSLLGGMFPLPRVIYAMARDGLLFKWLAQINSKtKTPINATV-VSGAIAALMAFLFdlkalvdlLSIGTLLAYSL 400

                  ..
gi 314927087  381 VA 382
Cdd:TIGR00906 401 VA 402
2A0308 TIGR00911
L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and ...
35-442 6.60e-12

L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273332 [Multi-domain]  Cd Length: 501  Bit Score: 67.46  E-value: 6.60e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087   35 IAIGGAIGTGLFLGSGKTISLAG-PSILLVYLIIGAVLffvmRAMGELLLSNLAY---KSFADFA--TDLVGPGAGFYmg 108
Cdd:TIGR00911  52 IIVGTIIGSGIFVSPKGVLKNAGsVGLALIMWAVCGIF----SIVGALVYAELGTtipKSGGEYNyiLEVFGPLLAFL-- 125
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  109 wTYWMCWVVIGNADTIAMCGYLAAWF----------PHLDKWIPATCIVLLLTCLNMVAVKLFGEMEFWFAMIKIvTIIA 178
Cdd:TIGR00911 126 -RLWIELLVIRPGSQAVNALNFAIYIltpvfpdcevPEWAIRLVAVLCVLLLTLVNCLSVKWATRVQDIFTACKL-LALL 203
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  179 LILVGGYLAITGFQpprsgvpaasFSHLWDRGGF--FPTGFMGFIAGFQIAIFSFQGIEMAGTAAAETADPEHNLPKAIN 256
Cdd:TIGR00911 204 LIIITGWVQLGKGG----------VESLNPKNAFegTETSAGGIVLAFYSGIWAYGGWNYLNFVTEEVKNPYRTLPIAII 273
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  257 SIPARVLIFYVLT-LGVIMAVQPWDLINPQASPfVEMFSFIGILIAFHIVNFVVLtSAASSANSGVFSTSRILYGLAREK 335
Cdd:TIGR00911 274 ISMPIVTFIYVLTnIAYFTVLSPEELLASLAVA-VDFGERLLGVMSWAMPALVGL-SCFGSVNGSLFSSSRLFFVGGREG 351
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  336 DAPPVFAKLSS-RHIPRNALILTamCIAPAIVLVTledsvMDAFSLVAGVSSVLYLSVwGLIlVCYLKYLgKHPQRHAES 414
Cdd:TIGR00911 352 HLPSLLSMIHVkRLTPLPSLLIV--CTLTLLMLFS-----GDIYSLINLISFANWLFN-ALA-VAGLLWL-RYKRPEMNR 421
                         410       420
                  ....*....|....*....|....*...
gi 314927087  415 AFKMPAgrvmsWVGILFFITILIMLGFS 442
Cdd:TIGR00911 422 PIKVPL-----FFPVFFLLSCLFLIILS 444
PRK10644 PRK10644
arginine/agmatine antiporter;
34-390 1.56e-11

arginine/agmatine antiporter;


Pssm-ID: 182613 [Multi-domain]  Cd Length: 445  Bit Score: 66.35  E-value: 1.56e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  34 LIAIGGAIGTGLFLGSGKTISLAGPSIL-LVYLIIGAV-LFFVMRAMGELLLSnlAYKSFAdFATDLVGPGAGFYMGWTY 111
Cdd:PRK10644  17 LMVAGNIMGSGVFLLPANLASTGGIAIYgWLVTIIGALgLSMVYAKMSSLDPS--PGGSYA-YARRCFGPFLGYQTNVLY 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 112 WM-CWvvIGN-ADTIAMCGYLAAWFPHLDKWI--PATCIVLL--LTCLNMVAVKLFGEMEfwfamiKIVTIIALILVGGy 185
Cdd:PRK10644  94 WLaCW--IGNiAMVVIGVGYLSYFFPILKDPLvlTITCVVVLwiFVLLNIVGPKMITRVQ------AVATVLALIPIVG- 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 186 LAITGFqpprSGVPAASFSHLWDRGGFFPTGFMGFIAGFqiAIFSFQGIEMAGTAAAETADPEHNLPKAINSIPARVLIF 265
Cdd:PRK10644 165 IAVFGW----FWFRGETYMAAWNVSGLGTFGAIQSTLNV--TLWSFIGVESASVAAGVVKNPKRNVPIATIGGVLIAAVC 238
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 266 YVLTLGVIMAVQPWDLINPQASPF---------------VEMFSFIGILIAFHIVNFVVLTSAASSANSGVFstsrilyg 330
Cdd:PRK10644 239 YVLSSTAIMGMIPNAALRVSASPFgdaarmalgdtagaiVSFCAAAGCLGSLGGWTLLAGQTAKAAADDGLF-------- 310
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 331 larekdaPPVFAKLSSRHIPRNALILTAMcIAPAIVLVTLEDSVMDAFSLVAGVSSVLYL 390
Cdd:PRK10644 311 -------PPIFARVNKAGTPVAGLLIVGV-LMTIFQLSSISPNASKEFGLVSSVSVIFTL 362
2A0302 TIGR00905
transporter, basic amino acid/polyamine antiporter (APA) family; This family includes several ...
32-458 2.89e-11

transporter, basic amino acid/polyamine antiporter (APA) family; This family includes several families of antiporters that, rather commonly, are encoded next to decarboxylases that convert one of the antiporter substrates into the other. This arrangement allows a cycle that can remove proteins from the cytoplasm and thereby protect against acidic conditions. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 129983  Cd Length: 473  Bit Score: 65.46  E-value: 2.89e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087   32 LQLIA--IGGAIGTGLFLGSGKTISLAGPSILLVYLIIGAV----LFFVMRAMGELLlSNLAYKSFAdFATDLVGPGAGF 105
Cdd:TIGR00905  12 FALTAlvIGSMIGSGIFSLPQNLASVAGPGAVIIGWIITGVgmlaLAFVFAILATKK-PELDGGIYA-YAREGFGPYIGF 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  106 YMGWTYWMCwVVIGN-ADTIAMCGYLAAWFPH---LDKW---IPATCIVLLLTCLNMVAVKlfgemefWFAMIKIVTIIA 178
Cdd:TIGR00905  90 MSGWGYWLS-AWIGNvAYAVLLFSALGYFFPLfgsGNPVpsiLGASVLLWVFTFLVLRGVR-------QAAFINTITTIA 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  179 LILVGGYLAITGFQPPRSGVPAASFshlWDRGGFFPTGFMGFIAG-FQIAIFSFQGIEMAgTAAAETADPEHNLPKAINS 257
Cdd:TIGR00905 162 KLIPLFLFIIIGWFWFKLDLFTADF---WGHDVPSLGSVFSQVKNtMLVTLWVFIGIEGA-VVSSGRAKNKSDVGKATVL 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  258 IPARVLIFYVLTLGVIMAVQPWD-LINPQASPFVEMFSFIGILIAFHIVNFVVLTSAASSANSGVFSTSRILYGLAREKD 336
Cdd:TIGR00905 238 GTLGALVIYILITLLSLGVLPQQeLANLPNPSMAAVLEMIVGKWGAVLISLGLIISVLGSLLSWTMLAAEVPFSAAKDGL 317
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  337 APPVFAKLSSRHIPRNALILTAMCIAPAIVLVTLedsVMDAFSLVAGVSSVlylsvwgLILVCYL---KYLGKHPQRHAE 413
Cdd:TIGR00905 318 FPKIFGRVNKNGAPSVALLLTNILIQLFLLLTLL---TSSAYNVLVSLAVV-------MILVPYLlsaAYLLKLAKVGTY 387
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*
gi 314927087  414 SAFKMPAGRVMSWVGILFFITILIMLGFSADSRQALIAAPVWVIF 458
Cdd:TIGR00905 388 PKIKNRKALIVGVIACVYSIWLLYAAGLKYLLLGFILYAPGIIFY 432
frlA PRK11357
amino acid permease;
22-472 3.38e-10

amino acid permease;


Pssm-ID: 183096 [Multi-domain]  Cd Length: 445  Bit Score: 62.18  E-value: 3.38e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  22 QLQRGLKNRHLQLIAIGGAIGTGLFLGSGKTISLAGPSILLV--YLIIGAVLFFVMRAMGELllsNLAYKSFADFATDLV 99
Cdd:PRK11357   5 ELQRKLGFWAVLAIAVGTTVGSGIFVSVGEVAKAAGTPWLTVlaFVIGGLIVIPQMCVYAEL---STAYPENGADYVYLK 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 100 GPGAGFYMGWTYWMCW-------VVIGNADTIAMCGYLAAWFPHLDKWIpATCIVLLLTCLNMVAVKLFGEMEFWFAMIK 172
Cdd:PRK11357  82 NAGSRPLAFLSGWASFwandapsLSIMALAIVSNLGFLTPIDPLLGKFI-AAGLIIAFMLLHLRSVEGGAAFQTLITIAK 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 173 IVTIIALILVGGYLAITG-FQPPRSGVPAASfshlwdrggffpTGFMGFIAGFQIAIFSFQGIEMAGTAAAETADPEHNL 251
Cdd:PRK11357 161 IIPFTIVIGLGIFWFKAEnFAAPTTTAIGAT------------GSFMALLAGISATSWSYTGMASICYMTGEIKNPGKTM 228
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 252 PKAINSIPARVLIFYVLTLGVIMAVQPWDLINPQASPFVEMFSFIGIL--IAFHIVNFVVLTSAASSANSGVFSTSRILY 329
Cdd:PRK11357 229 PRALIGSCLLVLVLYTLLALVISGLMPFDKLANSETPISDALTWIPALgsTAGIFVAITAMIVILGSLSSCVMYQPRLEY 308
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 330 GLAREKDAPPVFAKLSSRHIPRNALILTAMCIAPAIVLVTLEDSVMDAFSLVAGVSSVLylsVWGLILVCYLKylgkhpq 409
Cdd:PRK11357 309 AMAKDNLFFKCFGHVHPKYNTPDVSIILQGALGIFFIFVSDLTSLLGYFTLVMCFKNTL---TFGSIIWCRKR------- 378
                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 314927087 410 RHAESAFKMPAGRVMSWVGILFFItILIMLGFSADSRQALIAAPVWVIFMMVLYRLLASARAD 472
Cdd:PRK11357 379 DDYKPLWRTPAFGLMTTLAIASSL-ILVASTFVWAPIPGLICAVIVIATGLPAYAFWAKRSRQ 440
2A0304 TIGR00907
amino acid permease (GABA permease); [Transport and binding proteins, Amino acids, peptides ...
146-410 1.93e-04

amino acid permease (GABA permease); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273331 [Multi-domain]  Cd Length: 482  Bit Score: 43.97  E-value: 1.93e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  146 IVLLLTCLNMVAVKLFGEMEFWFAMIKIVTIIALILV-------GGYLAITGFQPprsgvpaasfshlwDRGGFFPTGFm 218
Cdd:TIGR00907 153 IHALINSLPTKWLPRITSSAAYWSLLGFLTICITLLAckspkfnDGKFVFTNFNN--------------STGGWKPGGF- 217
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  219 GFIAGFQIAIFSFQGIEMAGTAAAETADPEHNLPKAI-NSIPARVLIFYVLTLGVIMAVQ-PWDLIN-PQASPFVEMFS- 294
Cdd:TIGR00907 218 AFLLGLLNPAWSMTGYDGTAHMAEEIENPEVVGPRAIiGAVAIGIVTGFCFNIVLFFSMGdIDSLISsTTGQPIAQIFYn 297
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  295 ---------FIGILIAFhIVNFVVLTSAASSansgvfstSRILYGLAREKDAP--PVFAKLSSR-HIPRNALILTAMCIA 362
Cdd:TIGR00907 298 algnkagaiFLLCLILV-TSFFCAITCMTAN--------SRMIYAFSRDGGLPfsPLWSRVNPRtQVPLNAVWLSAVWII 368
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 314927087  363 pAIVLVTLEDSVmdAFSLVAGVSSVLYLSVWGLILVCYLKYLGKHPQR 410
Cdd:TIGR00907 369 -LIGLLGLGSST--AFQAIFSVCTVALDVSYVIPIICKLAKGRNTIAP 413
cadB PRK10435
cadaverine/lysine antiporter;
99-373 6.66e-04

cadaverine/lysine antiporter;


Pssm-ID: 182458  Cd Length: 435  Bit Score: 42.04  E-value: 6.66e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087  99 VGPGAGFYMGWTYWMC-WvvIGN-ADTIAMCGYLAAWFPHLDKWIPA----TCIVLLLTCLNMvavkLFGEMEFWFAMIK 172
Cdd:PRK10435  77 ISPAFGFQTGVLYYHAnW--IGNlAIGITAVSYLSTFFPVLNDPIPAgiacIAIVWVFTFVNM----LGGTWVSRLTTIG 150
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 173 IVTIIALILVGGYLAITGFQPprsgvpaASFSHLWDRGGffPTGFMGFIAGFQIAIFSFQGIEMAGTAAAETADPEHNLP 252
Cdd:PRK10435 151 LVLVLIPVVGTAIVGWHWFDA-------ATYAANWNTSD--TTDGHAIIKSILLCLWAFVGVESAAVSTGMVKNPKRTVP 221
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314927087 253 KAINSIPARVLIFYVLTLGVI---------------MAVQPWDLINPQASPFVEMFSFIGILIAFHIVNFVVLTSAASSA 317
Cdd:PRK10435 222 LATMLGTGLAGIIYIAATQVIsgmfpasvmaasgapFAISASTILGNWAAPLVSAFTAFACLTSLGSWMMLVGQAGVRAA 301
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 314927087 318 NSGVFstsrilyglarekdaPPVFAKLSSRHIPRNALILTAMCIAPAIVLVTLEDS 373
Cdd:PRK10435 302 NDGNF---------------PKVYGEVDKNGIPKKGLLLAAVKMTALMILITLMNS 342
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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