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Conserved domains on  [gi|315026096|gb|EFT38028|]
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pyridine nucleotide-disulfide oxidoreductase [Enterococcus faecalis TX2137]

Protein Classification

NAD(P)/FAD-dependent oxidoreductase( domain architecture ID 11441299)

NAD(P)/FAD-dependent oxidoreductase catalyzes the transfer of electrons from one molecule, the electron donor or reductant, to another molecule, the electron acceptor or oxidant; similar to sulfide:quinone oxidoreductase which catalyzes the oxidation of hydrogen sulfide using quinone as the electron acceptor

EC:  1.6.-.-
Gene Ontology:  GO:0003954|GO:0006116
PubMed:  15590775|28181562

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
Ndh COG1252
NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];
3-393 5.94e-140

NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];


:

Pssm-ID: 440864 [Multi-domain]  Cd Length: 386  Bit Score: 413.37  E-value: 5.94e-140
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096   3 KQNIVVVGAGYAGVSATKFLAKKFKKDtdVTITLIDRHSYHTMMTELHEVAGGRVEPEAIQYDLQRLFsRKKNVKLVTDT 82
Cdd:COG1252    1 MKRIVIVGGGFAGLEAARRLRKKLGGD--AEVTLIDPNPYHLFQPLLPEVAAGTLSPDDIAIPLRELL-RRAGVRFIQGE 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096  83 VTGIDKENKVVKTLAG-SYPFDQLILGMGGEPNDFGTPGVKENGFTLWSFDDAVKIRHHIEATVAKAAiepdaevRKAML 161
Cdd:COG1252   78 VTGIDPEARTVTLADGrTLSYDYLVIATGSVTNFFGIPGLAEHALPLKTLEDALALRERLLAAFERAE-------RRRLL 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096 162 TFVVCGSGFTGIEMVGELIDWKDRLAKDAKIDPDEITLMVVEAMPTILNMLSRNDAAKAERYLEKKNVQLLLNSPIVEVA 241
Cdd:COG1252  151 TIVVVGGGPTGVELAGELAELLRKLLRYPGIDPDKVRITLVEAGPRILPGLGEKLSEAAEKELEKRGVEVHTGTRVTEVD 230

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096 242 ADHIKLKDGSEVPTHTLIWTAGVKATSDAADFGLEAARGSRLVANEYMQAKGYEdkNIYIIGDLVYYEETPNTPTPQIVQ 321
Cdd:COG1252  231 ADGVTLEDGEEIPADTVIWAAGVKAPPLLADLGLPTDRRGRVLVDPTLQVPGHP--NVFAIGDCAAVPDPDGKPVPKTAQ 308

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 315026096 322 AAEQTGHTAAANIVADIKGGEKHAFKGNYQGFMVSIGAKWGVANLFdKIHLSGFLAIIMKHIVNLKYFFDIR 393
Cdd:COG1252  309 AAVQQAKVLAKNIAALLRGKPLKPFRYRDKGCLASLGRGAAVADVG-GLKLSGFLAWLLKRAIHLYFLPGFR 379
DoxX COG2259
Uncharacterized membrane protein YphA, DoxX/SURF4 family [Function unknown];
532-625 9.16e-05

Uncharacterized membrane protein YphA, DoxX/SURF4 family [Function unknown];


:

Pssm-ID: 441860  Cd Length: 134  Bit Score: 42.51  E-value: 9.16e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096 532 FDHMPKWFESvmkFMMPNQEVALFMqkfMTIVEVCIALALIAGLFTWLSSAATIGLTIAFCLS---GMFYWV------NI 602
Cdd:COG2259   33 FDGTAGFFAS---LGLPLPALLAYL---AGLAELVGGLLLILGLFTRLAALLLAGFMLVAIFVvhlPNGFWAmgggekNL 106

                         90       100
                 ....*....|....*....|....
gi 315026096 603 WFIFVAFALM-NGSGRaVGLDRWV 625
Cdd:COG2259  107 LLAGGLLALAlLGPGR-YSLDALL 129
 
Name Accession Description Interval E-value
Ndh COG1252
NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];
3-393 5.94e-140

NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];


Pssm-ID: 440864 [Multi-domain]  Cd Length: 386  Bit Score: 413.37  E-value: 5.94e-140
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096   3 KQNIVVVGAGYAGVSATKFLAKKFKKDtdVTITLIDRHSYHTMMTELHEVAGGRVEPEAIQYDLQRLFsRKKNVKLVTDT 82
Cdd:COG1252    1 MKRIVIVGGGFAGLEAARRLRKKLGGD--AEVTLIDPNPYHLFQPLLPEVAAGTLSPDDIAIPLRELL-RRAGVRFIQGE 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096  83 VTGIDKENKVVKTLAG-SYPFDQLILGMGGEPNDFGTPGVKENGFTLWSFDDAVKIRHHIEATVAKAAiepdaevRKAML 161
Cdd:COG1252   78 VTGIDPEARTVTLADGrTLSYDYLVIATGSVTNFFGIPGLAEHALPLKTLEDALALRERLLAAFERAE-------RRRLL 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096 162 TFVVCGSGFTGIEMVGELIDWKDRLAKDAKIDPDEITLMVVEAMPTILNMLSRNDAAKAERYLEKKNVQLLLNSPIVEVA 241
Cdd:COG1252  151 TIVVVGGGPTGVELAGELAELLRKLLRYPGIDPDKVRITLVEAGPRILPGLGEKLSEAAEKELEKRGVEVHTGTRVTEVD 230

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096 242 ADHIKLKDGSEVPTHTLIWTAGVKATSDAADFGLEAARGSRLVANEYMQAKGYEdkNIYIIGDLVYYEETPNTPTPQIVQ 321
Cdd:COG1252  231 ADGVTLEDGEEIPADTVIWAAGVKAPPLLADLGLPTDRRGRVLVDPTLQVPGHP--NVFAIGDCAAVPDPDGKPVPKTAQ 308

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 315026096 322 AAEQTGHTAAANIVADIKGGEKHAFKGNYQGFMVSIGAKWGVANLFdKIHLSGFLAIIMKHIVNLKYFFDIR 393
Cdd:COG1252  309 AAVQQAKVLAKNIAALLRGKPLKPFRYRDKGCLASLGRGAAVADVG-GLKLSGFLAWLLKRAIHLYFLPGFR 379
PTZ00318 PTZ00318
NADH dehydrogenase-like protein; Provisional
 1-379 2.84e-42

NADH dehydrogenase-like protein; Provisional


Pssm-ID: 185553 [Multi-domain]  Cd Length: 424  Bit Score: 158.39  E-value: 2.84e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096   1 MTKQNIVVVGAGYAGVSATKFL-AKKFKkdtdvtITLIDRHSYHTMMTELHEVAGGRVEPEAIQYDLQRLFSRKKNvKLV 79
Cdd:PTZ00318   8 LKKPNVVVLGTGWAGAYFVRNLdPKKYN------ITVISPRNHMLFTPLLPQTTTGTLEFRSICEPVRPALAKLPN-RYL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096  80 TDTVTGIDKENKVVKTLAGS-----------YPFDQLILGMGGEPNDFGTPGVKENGFTLWSFDDAVKIRHHIEATVAKA 148
Cdd:PTZ00318  81 RAVVYDVDFEEKRVKCGVVSksnnanvntfsVPYDKLVVAHGARPNTFNIPGVEERAFFLKEVNHARGIRKRIVQCIERA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096 149 AI-EPDAEVRKAMLTFVVCGSGFTGIEMVGELIDWKDRLAKdaKIDPD---EITLMVVEAMPTILNMLSRNDAAKAERYL 224
Cdd:PTZ00318 161 SLpTTSVEERKRLLHFVVVGGGPTGVEFAAELADFFRDDVR--NLNPElveECKVTVLEAGSEVLGSFDQALRKYGQRRL 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096 225 EKKNVQLLLNSPIVEVAADHIKLKDGSEVPTHTLIWTAGVKATSDAADFGLEAARGSRLVANEYMQAKGYEdkNIYIIGD 304
Cdd:PTZ00318 239 RRLGVDIRTKTAVKEVLDKEVVLKDGEVIPTGLVVWSTGVGPGPLTKQLKVDKTSRGRISVDDHLRVKPIP--NVFALGD 316

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 315026096 305 LVYYEetpNTPTPQIVQAAEQTGHTAAANIVADIKGG-EKHAFKGNYQGFMVSIGAKWGVANLfDKIHLSGFLAII 379
Cdd:PTZ00318 317 CAANE---ERPLPTLAQVASQQGVYLAKEFNNELKGKpMSKPFVYRSLGSLAYLGNYSAIVQL-GAFDLSGFKALL 388
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 5-327 2.10e-35

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 135.52  E-value: 2.10e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096    5 NIVVVGAGYAGVSATKFLAKKfkkdtDVTITLIDR---HSYHTMMteLHEVAGGRVEPEAIQYDLQRLFSRKKNV----- 76
Cdd:pfam07992   2 DVVVIGGGPAGLAAALTLAQL-----GGKVTLIEDegtCPYGGCV--LSKALLGAAEAPEIASLWADLYKRKEEVvkkln 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096   77 ----KLVTDTVTGIDKENKVVKTLAG------SYPFDQLILGMGGEPNDFGTPGVKENGFTLWS-FDDAVKIRHHieatv 145
Cdd:pfam07992  75 ngieVLLGTEVVSIDPGAKKVVLEELvdgdgeTITYDRLVIATGARPRLPPIPGVELNVGFLVRtLDSAEALRLK----- 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096  146 akaaiepdaEVRKamlTFVVCGSGFTGIEMVGELIdwkdRLAKDAkidpdeitlMVVEAMPTILNMLSRNDAAKAERYLE 225
Cdd:pfam07992 150 ---------LLPK---RVVVVGGGYIGVELAAALA----KLGKEV---------TLIEALDRLLRAFDEEISAALEKALE 204

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096  226 KKNVQLLLNSPIVEVAAD----HIKLKDGSEVPTHTLIWTAGVKATSDAADF-GLEAARGSRLVANEYMQAKgyeDKNIY 300
Cdd:pfam07992 205 KNGVEVRLGTSVKEIIGDgdgvEVILKDGTEIDADLVVVAIGRRPNTELLEAaGLELDERGGIVVDEYLRTS---VPGIY 281

                         330       340
                  ....*....|....*....|....*..
gi 315026096  301 IIGDLVYyeetpntPTPQIVQAAEQTG 327
Cdd:pfam07992 282 AAGDCRV-------GGPELAQNAVAQG 301
lipoamide_DH TIGR01350
dihydrolipoamide dehydrogenase; This model describes dihydrolipoamide dehydrogenase, a ...
 5-334 6.45e-11

dihydrolipoamide dehydrogenase; This model describes dihydrolipoamide dehydrogenase, a flavoprotein that acts in a number of ways. It is the E3 component of dehydrogenase complexes for pyruvate, 2-oxoglutarate, 2-oxoisovalerate, and acetoin. It can also serve as the L protein of the glycine cleavage system. This family includes a few members known to have distinct functions (ferric leghemoglobin reductase and NADH:ferredoxin oxidoreductase) but that may be predicted by homology to act as dihydrolipoamide dehydrogenase as well. The motif GGXCXXXGCXP near the N-terminus contains a redox-active disulfide.


Pssm-ID: 273568 [Multi-domain]  Cd Length: 460  Bit Score: 64.97  E-value: 6.45e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096    5 NIVVVGAGYAG-VSATKflAKKFKKDTDV-----------------TITLIdrHSYHTMmTELHEVAGGRVEPEAIQYDL 66
Cdd:TIGR01350   3 DVIVIGGGPGGyVAAIR--AAQLGLKVALvekeylggtclnvgcipTKALL--HSAEVY-DEIKHAKDLGIEVENVSVDW 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096   67 QRLFSRK-KNVKLVTDTVTGIDKENKVV------------------KTLAGSYPFDQLILGMGGEPNDFGTPgVKENGFT 127
Cdd:TIGR01350  78 EKMQKRKnKVVKKLVGGVSGLLKKNKVTvikgeakfldpgtvsvtgENGEETLEAKNIIIATGSRPRSLPGP-FDFDGKV 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096  128 LWSFDDAVKIRhhieatvakaaiepdaEVRKAMltfVVCGSGFTGIEMVGELidwkDRLAKDakidpdeitLMVVEAMPT 207
Cdd:TIGR01350 157 VITSTGALNLE----------------EVPESL---VIIGGGVIGIEFASIF----ASLGSK---------VTVIEMLDR 204

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096  208 ILNMLSRNDAAKAERYLEKKNVQLLLNSPI--VEVAADHIKLK-DGSEVPTHT----LIwTAGVKATSDaaDFGLEAA-- 278
Cdd:TIGR01350 205 ILPGEDAEVSKVLQKALKKKGVKILTNTKVtaVEKNDDQVTYEnKGGETETLTgekvLV-AVGRKPNTE--GLGLEKLgv 281

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096  279 ----RGsRLVANEYMQAKgyeDKNIYIIGDLvyyeetpnTPTPQIVQAAEQTGHTAAANI 334
Cdd:TIGR01350 282 eldeRG-RIVVDEYMRTN---VPGIYAIGDV--------IGGPMLAHVASHEGIVAAENI 329
DoxX COG2259
Uncharacterized membrane protein YphA, DoxX/SURF4 family [Function unknown];
532-625 9.16e-05

Uncharacterized membrane protein YphA, DoxX/SURF4 family [Function unknown];


Pssm-ID: 441860  Cd Length: 134  Bit Score: 42.51  E-value: 9.16e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096 532 FDHMPKWFESvmkFMMPNQEVALFMqkfMTIVEVCIALALIAGLFTWLSSAATIGLTIAFCLS---GMFYWV------NI 602
Cdd:COG2259   33 FDGTAGFFAS---LGLPLPALLAYL---AGLAELVGGLLLILGLFTRLAALLLAGFMLVAIFVvhlPNGFWAmgggekNL 106

                         90       100
                 ....*....|....*....|....
gi 315026096 603 WFIFVAFALM-NGSGRaVGLDRWV 625
Cdd:COG2259  107 LLAGGLLALAlLGPGR-YSLDALL 129
 
Name Accession Description Interval E-value
Ndh COG1252
NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];
3-393 5.94e-140

NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];


Pssm-ID: 440864 [Multi-domain]  Cd Length: 386  Bit Score: 413.37  E-value: 5.94e-140
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096   3 KQNIVVVGAGYAGVSATKFLAKKFKKDtdVTITLIDRHSYHTMMTELHEVAGGRVEPEAIQYDLQRLFsRKKNVKLVTDT 82
Cdd:COG1252    1 MKRIVIVGGGFAGLEAARRLRKKLGGD--AEVTLIDPNPYHLFQPLLPEVAAGTLSPDDIAIPLRELL-RRAGVRFIQGE 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096  83 VTGIDKENKVVKTLAG-SYPFDQLILGMGGEPNDFGTPGVKENGFTLWSFDDAVKIRHHIEATVAKAAiepdaevRKAML 161
Cdd:COG1252   78 VTGIDPEARTVTLADGrTLSYDYLVIATGSVTNFFGIPGLAEHALPLKTLEDALALRERLLAAFERAE-------RRRLL 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096 162 TFVVCGSGFTGIEMVGELIDWKDRLAKDAKIDPDEITLMVVEAMPTILNMLSRNDAAKAERYLEKKNVQLLLNSPIVEVA 241
Cdd:COG1252  151 TIVVVGGGPTGVELAGELAELLRKLLRYPGIDPDKVRITLVEAGPRILPGLGEKLSEAAEKELEKRGVEVHTGTRVTEVD 230

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096 242 ADHIKLKDGSEVPTHTLIWTAGVKATSDAADFGLEAARGSRLVANEYMQAKGYEdkNIYIIGDLVYYEETPNTPTPQIVQ 321
Cdd:COG1252  231 ADGVTLEDGEEIPADTVIWAAGVKAPPLLADLGLPTDRRGRVLVDPTLQVPGHP--NVFAIGDCAAVPDPDGKPVPKTAQ 308

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 315026096 322 AAEQTGHTAAANIVADIKGGEKHAFKGNYQGFMVSIGAKWGVANLFdKIHLSGFLAIIMKHIVNLKYFFDIR 393
Cdd:COG1252  309 AAVQQAKVLAKNIAALLRGKPLKPFRYRDKGCLASLGRGAAVADVG-GLKLSGFLAWLLKRAIHLYFLPGFR 379
PTZ00318 PTZ00318
NADH dehydrogenase-like protein; Provisional
 1-379 2.84e-42

NADH dehydrogenase-like protein; Provisional


Pssm-ID: 185553 [Multi-domain]  Cd Length: 424  Bit Score: 158.39  E-value: 2.84e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096   1 MTKQNIVVVGAGYAGVSATKFL-AKKFKkdtdvtITLIDRHSYHTMMTELHEVAGGRVEPEAIQYDLQRLFSRKKNvKLV 79
Cdd:PTZ00318   8 LKKPNVVVLGTGWAGAYFVRNLdPKKYN------ITVISPRNHMLFTPLLPQTTTGTLEFRSICEPVRPALAKLPN-RYL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096  80 TDTVTGIDKENKVVKTLAGS-----------YPFDQLILGMGGEPNDFGTPGVKENGFTLWSFDDAVKIRHHIEATVAKA 148
Cdd:PTZ00318  81 RAVVYDVDFEEKRVKCGVVSksnnanvntfsVPYDKLVVAHGARPNTFNIPGVEERAFFLKEVNHARGIRKRIVQCIERA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096 149 AI-EPDAEVRKAMLTFVVCGSGFTGIEMVGELIDWKDRLAKdaKIDPD---EITLMVVEAMPTILNMLSRNDAAKAERYL 224
Cdd:PTZ00318 161 SLpTTSVEERKRLLHFVVVGGGPTGVEFAAELADFFRDDVR--NLNPElveECKVTVLEAGSEVLGSFDQALRKYGQRRL 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096 225 EKKNVQLLLNSPIVEVAADHIKLKDGSEVPTHTLIWTAGVKATSDAADFGLEAARGSRLVANEYMQAKGYEdkNIYIIGD 304
Cdd:PTZ00318 239 RRLGVDIRTKTAVKEVLDKEVVLKDGEVIPTGLVVWSTGVGPGPLTKQLKVDKTSRGRISVDDHLRVKPIP--NVFALGD 316

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 315026096 305 LVYYEetpNTPTPQIVQAAEQTGHTAAANIVADIKGG-EKHAFKGNYQGFMVSIGAKWGVANLfDKIHLSGFLAII 379
Cdd:PTZ00318 317 CAANE---ERPLPTLAQVASQQGVYLAKEFNNELKGKpMSKPFVYRSLGSLAYLGNYSAIVQL-GAFDLSGFKALL 388
NirB COG1251
NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];
3-348 4.00e-42

NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];


Pssm-ID: 440863 [Multi-domain]  Cd Length: 402  Bit Score: 157.23  E-value: 4.00e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096   3 KQNIVVVGAGYAGVSATKFLAkkfKKDTDVTITLI---DRHSYHTMMteLHEVAGGRVEPEAIQYDLQRLFsRKKNVKLV 79
Cdd:COG1251    1 KMRIVIIGAGMAGVRAAEELR---KLDPDGEITVIgaePHPPYNRPP--LSKVLAGETDEEDLLLRPADFY-EENGIDLR 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096  80 TDT-VTGIDKENKVVKTLAGS-YPFDQLILGMGGEPNDFGTPGV-KENGFTLWSFDDAVKIRhhieatvakAAIEPDAEV 156
Cdd:COG1251   75 LGTrVTAIDRAARTVTLADGEtLPYDKLVLATGSRPRVPPIPGAdLPGVFTLRTLDDADALR---------AALAPGKRV 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096 157 rkamltfVVCGSGFTGIEmvgelidwkdrLAKDAK---IDPDeitlmVVEAMPTILN-MLSRNDAAKAERYLEKKNVQLL 232
Cdd:COG1251  146 -------VVIGGGLIGLE-----------AAAALRkrgLEVT-----VVERAPRLLPrQLDEEAGALLQRLLEALGVEVR 202

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096 233 LNSPIVEVAADH----IKLKDGSEVPTHTLIWTAGVKATSD-AADFGLEAARGsrLVANEYMQAkgyEDKNIYIIGDLV- 306
Cdd:COG1251  203 LGTGVTEIEGDDrvtgVRLADGEELPADLVVVAIGVRPNTElARAAGLAVDRG--IVVDDYLRT---SDPDIYAAGDCAe 277

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|..
gi 315026096 307 YYEETPNTPTPQIVQAAEQTGHTAAANIVadikgGEKHAFKG 348
Cdd:COG1251  278 HPGPVYGRRVLELVAPAYEQARVAAANLA-----GGPAAYEG 314
FadH2 COG0446
NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase ...
 27-368 1.34e-37

NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase [Lipid transport and metabolism];


Pssm-ID: 440215 [Multi-domain]  Cd Length: 322  Bit Score: 142.26  E-value: 1.34e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096  27 KKDTDVTITLIDR---HSYHTMMTELHeVAGGRVEPEAIQYDLQRLFsRKKNVKLVT-DTVTGIDKENKVVKTLAG-SYP 101
Cdd:COG0446    1 RLGPDAEITVIEKgphHSYQPCGLPYY-VGGGIKDPEDLLVRTPESF-ERKGIDVRTgTEVTAIDPEAKTVTLRDGeTLS 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096 102 FDQLILGMGGEPNDFGTPGVKENG-FTLWSFDDAVKIRHHIEatvakaaiepDAEVRKAmltfVVCGSGFTGIEMVGELI 180
Cdd:COG0446   79 YDKLVLATGARPRPPPIPGLDLPGvFTLRTLDDADALREALK----------EFKGKRA----VVIGGGPIGLELAEALR 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096 181 dwkdrlAKDAKIDpdeitlmVVEAMPTILNMLSRNDAAKAERYLEKKNVQLLLNSPIVEVAADH---IKLKDGSEVPTHT 257
Cdd:COG0446  145 ------KRGLKVT-------LVERAPRLLGVLDPEMAALLEEELREHGVELRLGETVVAIDGDDkvaVTLTDGEEIPADL 211

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096 258 LIWTAGVKATSD-AADFGLE-AARGSRLVaNEYMQAKgyeDKNIYIIGDLVyyeETPNTPTPQIV-----QAAEQTGHTA 330
Cdd:COG0446  212 VVVAPGVRPNTElAKDAGLAlGERGWIKV-DETLQTS---DPDVYAAGDCA---EVPHPVTGKTVyiplaSAANKQGRVA 284

                        330       340       350
                 ....*....|....*....|....*....|....*...
gi 315026096 331 AANIVadikgGEKHAFKgnyqgfmvsiGAKWGVANLFD 368
Cdd:COG0446  285 AENIL-----GGPAPFP----------GLGTFISKVFD 307
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 5-327 2.10e-35

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 135.52  E-value: 2.10e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096    5 NIVVVGAGYAGVSATKFLAKKfkkdtDVTITLIDR---HSYHTMMteLHEVAGGRVEPEAIQYDLQRLFSRKKNV----- 76
Cdd:pfam07992   2 DVVVIGGGPAGLAAALTLAQL-----GGKVTLIEDegtCPYGGCV--LSKALLGAAEAPEIASLWADLYKRKEEVvkkln 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096   77 ----KLVTDTVTGIDKENKVVKTLAG------SYPFDQLILGMGGEPNDFGTPGVKENGFTLWS-FDDAVKIRHHieatv 145
Cdd:pfam07992  75 ngieVLLGTEVVSIDPGAKKVVLEELvdgdgeTITYDRLVIATGARPRLPPIPGVELNVGFLVRtLDSAEALRLK----- 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096  146 akaaiepdaEVRKamlTFVVCGSGFTGIEMVGELIdwkdRLAKDAkidpdeitlMVVEAMPTILNMLSRNDAAKAERYLE 225
Cdd:pfam07992 150 ---------LLPK---RVVVVGGGYIGVELAAALA----KLGKEV---------TLIEALDRLLRAFDEEISAALEKALE 204

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096  226 KKNVQLLLNSPIVEVAAD----HIKLKDGSEVPTHTLIWTAGVKATSDAADF-GLEAARGSRLVANEYMQAKgyeDKNIY 300
Cdd:pfam07992 205 KNGVEVRLGTSVKEIIGDgdgvEVILKDGTEIDADLVVVAIGRRPNTELLEAaGLELDERGGIVVDEYLRTS---VPGIY 281

                         330       340
                  ....*....|....*....|....*..
gi 315026096  301 IIGDLVYyeetpntPTPQIVQAAEQTG 327
Cdd:pfam07992 282 AAGDCRV-------GGPELAQNAVAQG 301
Lpd COG1249
Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex ...
 1-337 2.77e-14

Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase [Energy production and conversion]; Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase is part of the Pathway/BioSystem: Glycine cleavagePyruvate oxidation


Pssm-ID: 440861 [Multi-domain]  Cd Length: 456  Bit Score: 75.51  E-value: 2.77e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096   1 MTKQNIVVVGAGYAGVSATKFLAKKFKKdtdvtITLIDRHSY----------------HT--MMTELHEVAGGRVEPEAI 62
Cdd:COG1249    1 MKDYDLVVIGAGPGGYVAAIRAAQLGLK-----VALVEKGRLggtclnvgcipskallHAaeVAHEARHAAEFGISAGAP 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096  63 QYDLQRLFSRKKNV--KLVTDTVTGIDKENkvVKTLAGS----------------YPFDQLILGMGGEPNDFGTPGVKEN 124
Cdd:COG1249   76 SVDWAALMARKDKVvdRLRGGVEELLKKNG--VDVIRGRarfvdphtvevtggetLTADHIVIATGSRPRVPPIPGLDEV 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096 125 GFtlWSFDDAVKIRH---HIeatvakaaiepdaevrkamltfVVCGSGFTGIEMVGELidwkDRLakDAKIDpdeitlmV 201
Cdd:COG1249  154 RV--LTSDEALELEElpkSL----------------------VVIGGGYIGLEFAQIF----ARL--GSEVT-------L 196

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096 202 VEAMPTILNMLSRnDAAKA-ERYLEKKNVQLLLNSPIVEVAAD----HIKLKDGSEVPTHT---LIWTAGVKATSDaaDF 273
Cdd:COG1249  197 VERGDRLLPGEDP-EISEAlEKALEKEGIDILTGAKVTSVEKTgdgvTVTLEDGGGEEAVEadkVLVATGRRPNTD--GL 273

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096 274 GLEAA------RGsRLVANEYMQAKgyeDKNIYIIGDLvyyeetpnTPTPQIVQAAEQTGHTAAANIVAD 337
Cdd:COG1249  274 GLEAAgveldeRG-GIKVDEYLRTS---VPGIYAIGDV--------TGGPQLAHVASAEGRVAAENILGK 331
PRK04965 PRK04965
NADH:flavorubredoxin reductase NorW;
5-304 9.36e-12

NADH:flavorubredoxin reductase NorW;


Pssm-ID: 179902 [Multi-domain]  Cd Length: 377  Bit Score: 67.25  E-value: 9.36e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096   5 NIVVVGAGYAGVSATKFLAKKfkkDTDVTITLI---DRHSYHTmmTELHEVAGGRVEPEaiqyDLQRL----FSRKKNVK 77
Cdd:PRK04965   4 GIVIIGSGFAARQLVKNIRKQ---DAHIPITLItadSGDEYNK--PDLSHVFSQGQRAD----DLTRQsageFAEQFNLR 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096  78 LVTDT-VTGIDKENKVVKTLAGSYPFDQLILgmggepndfgtpgvkengftlwsfddavkirhhieATVAKAAIePDAEV 156
Cdd:PRK04965  75 LFPHTwVTDIDAEAQVVKSQGNQWQYDKLVL-----------------------------------ATGASAFV-PPIPG 118

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096 157 RKAMLTF-------------------VVCGSGFTGIEmvgelidwkdrLAKDAKIDPDEITLmvVEAMPTIL-NMLSRND 216
Cdd:PRK04965 119 RELMLTLnsqqeyraaetqlrdaqrvLVVGGGLIGTE-----------LAMDLCRAGKAVTL--VDNAASLLaSLMPPEV 185

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096 217 AAKAERYLEKKNVQLLLNSPI--VEVAADHIK--LKDGSEVPTHTLIWTAGVKA-TSDAADFGLEAARGsrLVANEYMQA 291
Cdd:PRK04965 186 SSRLQHRLTEMGVHLLLKSQLqgLEKTDSGIRatLDSGRSIEVDAVIAAAGLRPnTALARRAGLAVNRG--IVVDSYLQT 263

                        330
                 ....*....|...
gi 315026096 292 kgyEDKNIYIIGD 304
Cdd:PRK04965 264 ---SAPDIYALGD 273
PRK06416 PRK06416
dihydrolipoamide dehydrogenase; Reviewed
 6-334 2.79e-11

dihydrolipoamide dehydrogenase; Reviewed


Pssm-ID: 235798 [Multi-domain]  Cd Length: 462  Bit Score: 65.94  E-value: 2.79e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096   6 IVVVGAGYAGVSATKFLAKKFKKdtdvtITLIDR----------------------HSYHtmmtELHEVAGGRVEPEAIQ 63
Cdd:PRK06416   7 VIVIGAGPGGYVAAIRAAQLGLK-----VAIVEKeklggtclnrgcipskallhaaERAD----EARHSEDFGIKAENVG 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096  64 YDLQRLFSRKKNV--KLVTDtVTGIDKENKV----------------VKTLAGS--YPFDQLILGMGGEPndFGTPGVKE 123
Cdd:PRK06416  78 IDFKKVQEWKNGVvnRLTGG-VEGLLKKNKVdiirgeaklvdpntvrVMTEDGEqtYTAKNIILATGSRP--RELPGIEI 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096 124 NGFTLWSFDDAVKIRHhieatVAKAAIepdaevrkamltfvVCGSGFTGIEMVGElidWKDRLAkdakidpdEITlmVVE 203
Cdd:PRK06416 155 DGRVIWTSDEALNLDE-----VPKSLV--------------VIGGGYIGVEFASA---YASLGA--------EVT--IVE 202

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096 204 AMPTILNMLSRNDAAKAERYLEKKNVQLLLNSPI--VEVAADHIKLK--DGSEVPTHT---LIWTAGVKATSDaaDFGLE 276
Cdd:PRK06416 203 ALPRILPGEDKEISKLAERALKKRGIKIKTGAKAkkVEQTDDGVTVTleDGGKEETLEadyVLVAVGRRPNTE--NLGLE 280

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 315026096 277 AA-----RGSrLVANEYMQAkgyEDKNIYIIGDLVyyeetpntPTPQIVQAAEQTGHTAAANI 334
Cdd:PRK06416 281 ELgvktdRGF-IEVDEQLRT---NVPNIYAIGDIV--------GGPMLAHKASAEGIIAAEAI 331
lipoamide_DH TIGR01350
dihydrolipoamide dehydrogenase; This model describes dihydrolipoamide dehydrogenase, a ...
 5-334 6.45e-11

dihydrolipoamide dehydrogenase; This model describes dihydrolipoamide dehydrogenase, a flavoprotein that acts in a number of ways. It is the E3 component of dehydrogenase complexes for pyruvate, 2-oxoglutarate, 2-oxoisovalerate, and acetoin. It can also serve as the L protein of the glycine cleavage system. This family includes a few members known to have distinct functions (ferric leghemoglobin reductase and NADH:ferredoxin oxidoreductase) but that may be predicted by homology to act as dihydrolipoamide dehydrogenase as well. The motif GGXCXXXGCXP near the N-terminus contains a redox-active disulfide.


Pssm-ID: 273568 [Multi-domain]  Cd Length: 460  Bit Score: 64.97  E-value: 6.45e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096    5 NIVVVGAGYAG-VSATKflAKKFKKDTDV-----------------TITLIdrHSYHTMmTELHEVAGGRVEPEAIQYDL 66
Cdd:TIGR01350   3 DVIVIGGGPGGyVAAIR--AAQLGLKVALvekeylggtclnvgcipTKALL--HSAEVY-DEIKHAKDLGIEVENVSVDW 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096   67 QRLFSRK-KNVKLVTDTVTGIDKENKVV------------------KTLAGSYPFDQLILGMGGEPNDFGTPgVKENGFT 127
Cdd:TIGR01350  78 EKMQKRKnKVVKKLVGGVSGLLKKNKVTvikgeakfldpgtvsvtgENGEETLEAKNIIIATGSRPRSLPGP-FDFDGKV 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096  128 LWSFDDAVKIRhhieatvakaaiepdaEVRKAMltfVVCGSGFTGIEMVGELidwkDRLAKDakidpdeitLMVVEAMPT 207
Cdd:TIGR01350 157 VITSTGALNLE----------------EVPESL---VIIGGGVIGIEFASIF----ASLGSK---------VTVIEMLDR 204

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096  208 ILNMLSRNDAAKAERYLEKKNVQLLLNSPI--VEVAADHIKLK-DGSEVPTHT----LIwTAGVKATSDaaDFGLEAA-- 278
Cdd:TIGR01350 205 ILPGEDAEVSKVLQKALKKKGVKILTNTKVtaVEKNDDQVTYEnKGGETETLTgekvLV-AVGRKPNTE--GLGLEKLgv 281

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096  279 ----RGsRLVANEYMQAKgyeDKNIYIIGDLvyyeetpnTPTPQIVQAAEQTGHTAAANI 334
Cdd:TIGR01350 282 eldeRG-RIVVDEYMRTN---VPGIYAIGDV--------IGGPMLAHVASHEGIVAAENI 329
PRK09754 PRK09754
phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional
 1-305 2.55e-08

phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional


Pssm-ID: 170080 [Multi-domain]  Cd Length: 396  Bit Score: 56.47  E-value: 2.55e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096   1 MTKQNIVVVGAGYAGVSATKFLAKK-FKKDtdvtITLIDRHsYHTMMTELHEVAGGRVEPE-AIQYDLQRLFSRKKNVKL 78
Cdd:PRK09754   1 MKEKTIIIVGGGQAAAMAAASLRQQgFTGE----LHLFSDE-RHLPYERPPLSKSMLLEDSpQLQQVLPANWWQENNVHL 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096  79 -VTDTVTGIDK-ENKVVKTLAGSYPFDQLILGMGGEPNDFGT-PGVKENGFTLWSFDDAVKIRHhieatvakaAIEPDAE 155
Cdd:PRK09754  76 hSGVTIKTLGRdTRELVLTNGESWHWDQLFIATGAAARPLPLlDALGERCFTLRHAGDAARLRE---------VLQPERS 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096 156 VrkamltfVVCGSGFTGIEmvgelidwkdrLAKDAKIDPDEITlmVVEAMPTIlnmLSRNDAAKAERYL----EKKNVQL 231
Cdd:PRK09754 147 V-------VIVGAGTIGLE-----------LAASATQRRCKVT--VIELAATV---MGRNAPPPVQRYLlqrhQQAGVRI 203

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 315026096 232 LLNSPIVEVAADH---IKLKDGSEVPTHTLIWTAGVKATSD-AADFGLEAARGsrLVANEYMQAKgyeDKNIYIIGDL 305
Cdd:PRK09754 204 LLNNAIEHVVDGEkveLTLQSGETLQADVVIYGIGISANDQlAREANLDTANG--IVIDEACRTC---DPAIFAGGDV 276
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
6-340 2.64e-08

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 55.90  E-value: 2.64e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096   6 IVVVGAGYAGVSATkFLAKKFKKDTdvtiTLIDRHSYH---TMMTELHEVAGgrvEPEAIQ-YDL-QRLFS--RKKNVKL 78
Cdd:COG0492    3 VVIIGAGPAGLTAA-IYAARAGLKT----LVIEGGEPGgqlATTKEIENYPG---FPEGISgPELaERLREqaERFGAEI 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096  79 VTDTVTGIDKEN--KVVKTLAG-SYPFDQLILGMGGEPNDFGTPGVKEngFTlwsfddavkiRHHIEATVA-KAAIEPDA 154
Cdd:COG0492   75 LLEEVTSVDKDDgpFRVTTDDGtEYEAKAVIIATGAGPRKLGLPGEEE--FE----------GRGVSYCATcDGFFFRGK 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096 155 EVrkamltfVVCGSGFTGIEMVgelidwkDRLAKDAKidpdEITLMVveamptilnmlsRNDAAKAERYL-----EKKNV 229
Cdd:COG0492  143 DV-------VVVGGGDSALEEA-------LYLTKFAS----KVTLIH------------RRDELRASKILverlrANPKI 192

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096 230 QLLLNSPIVEVAAD----HIKLKDG-----SEVPTHTLIWTAGVKATSD-AADFGLEAARGSRLVANEYMQAKgyeDKNI 299
Cdd:COG0492  193 EVLWNTEVTEIEGDgrveGVTLKNVktgeeKELEVDGVFVAIGLKPNTElLKGLGLELDEDGYIVVDEDMETS---VPGV 269

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|.
gi 315026096 300 YIIGDLVYYeetpntPTPQIVQAAEQtGHTAAANIVADIKG 340
Cdd:COG0492  270 FAAGDVRDY------KYRQAATAAGE-GAIAALSAARYLEP 303
PRK09564 PRK09564
coenzyme A disulfide reductase; Reviewed
 6-348 4.57e-08

coenzyme A disulfide reductase; Reviewed


Pssm-ID: 181958 [Multi-domain]  Cd Length: 444  Bit Score: 55.82  E-value: 4.57e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096   6 IVVVGAGYAGVS-ATKflAKKFKKDTDVTItlidrhsYHtmMTE--------LHEVAGGRVEpeaiqyDLQRLFSR---- 72
Cdd:PRK09564   3 IIIIGGTAAGMSaAAK--AKRLNKELEITV-------YE--KTDivsfgacgLPYFVGGFFD------DPNTMIARtpee 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096  73 --KKNVKLVTDT-VTGIDKENK--VVKTLAGSYPF----DQLILGMGGEPNDFGTPGVK-ENGFTLWSFDDAVKIRHHIE 142
Cdd:PRK09564  66 fiKSGIDVKTEHeVVKVDAKNKtiTVKNLKTGSIFndtyDKLMIATGARPIIPPIKNINlENVYTLKSMEDGLALKELLK 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096 143 atvakaaiepDAEVRKAmltfVVCGSGFTGIEMVGE---------LIDWKDRLAKDaKIDPdEITLMVVEAmptilnmls 213
Cdd:PRK09564 146 ----------DEEIKNI----VIIGAGFIGLEAVEAakhlgknvrIIQLEDRILPD-SFDK-EITDVMEEE--------- 200

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096 214 rndaakaeryLEKKNVQLLLNSPIVEVAAD---HIKLKDGSEVPTHTLIWTAGVKATSD-AADFGLEAARGSRLVANEYM 289
Cdd:PRK09564 201 ----------LRENGVELHLNEFVKSLIGEdkvEGVVTDKGEYEADVVIVATGVKPNTEfLEDTGLKTLKNGAIIVDEYG 270

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 315026096 290 QAkgyEDKNIYIIGD--LVYyeetpNTPTPQIVQAAEQTGHTAAANIVADIKGGEKHAFKG 348
Cdd:PRK09564 271 ET---SIENIYAAGDcaTIY-----NIVSNKNVYVPLATTANKLGRMVGENLAGRHVSFKG 323
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 4-117 4.13e-06

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 49.24  E-value: 4.13e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096    4 QNIVVVGAGYAGVSATKFLAKKFKKdtdvtITLIDRhsyhtmMTELhevagGRVEPEAIQYDLQRLFsRKKNVKLVTDT- 82
Cdd:pfam07992 153 KRVVVVGGGYIGVELAAALAKLGKE-----VTLIEA------LDRL-----LRAFDEEISAALEKAL-EKNGVEVRLGTs 215

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 315026096   83 VTGIDKENKVVKTLAG---SYPFDQLILGMGGEPNDFG 117
Cdd:pfam07992 216 VKEIIGDGDGVEVILKdgtEIDADLVVVAIGRRPNTEL 253
FadH2 COG0446
NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase ...
 4-114 1.60e-05

NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase [Lipid transport and metabolism];


Pssm-ID: 440215 [Multi-domain]  Cd Length: 322  Bit Score: 47.50  E-value: 1.60e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096   4 QNIVVVGAGYAGVSATKFLAKKFKKdtdvtITLIDRHSYhtMMtelhevagGRVEPEAIQYDLQRLfsRKKNVKLVT-DT 82
Cdd:COG0446  125 KRAVVIGGGPIGLELAEALRKRGLK-----VTLVERAPR--LL--------GVLDPEMAALLEEEL--REHGVELRLgET 187

                         90       100       110
                 ....*....|....*....|....*....|....
gi 315026096  83 VTGIDKENKVVKTLA--GSYPFDQLILGMGGEPN 114
Cdd:COG0446  188 VVAIDGDDKVAVTLTdgEEIPADLVVVAPGVRPN 221
Pyr_redox pfam00070
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 164-250 1.98e-05

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 425450 [Multi-domain]  Cd Length: 80  Bit Score: 42.96  E-value: 1.98e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096  164 VVCGSGFTGIEMVGELIdwkdRLAKdakidpdEITlmVVEAMPTILNMLSRNDAAKAERYLEKKNVQLLLNSPIVEVAAD 243
Cdd:pfam00070   3 VVVGGGYIGLELAGALA----RLGS-------KVT--VVERRDRLLPGFDPEIAKILQEKLEKNGIEFLLNTTVEAIEGN 69

                          90
                  ....*....|.
gi 315026096  244 ----HIKLKDG 250
Cdd:pfam00070  70 gdgvVVVLTDG 80
DoxX COG2259
Uncharacterized membrane protein YphA, DoxX/SURF4 family [Function unknown];
532-625 9.16e-05

Uncharacterized membrane protein YphA, DoxX/SURF4 family [Function unknown];


Pssm-ID: 441860  Cd Length: 134  Bit Score: 42.51  E-value: 9.16e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096 532 FDHMPKWFESvmkFMMPNQEVALFMqkfMTIVEVCIALALIAGLFTWLSSAATIGLTIAFCLS---GMFYWV------NI 602
Cdd:COG2259   33 FDGTAGFFAS---LGLPLPALLAYL---AGLAELVGGLLLILGLFTRLAALLLAGFMLVAIFVvhlPNGFWAmgggekNL 106

                         90       100
                 ....*....|....*....|....
gi 315026096 603 WFIFVAFALM-NGSGRaVGLDRWV 625
Cdd:COG2259  107 LLAGGLLALAlLGPGR-YSLDALL 129
PRK06292 PRK06292
dihydrolipoamide dehydrogenase; Validated
 1-341 5.36e-04

dihydrolipoamide dehydrogenase; Validated


Pssm-ID: 235774 [Multi-domain]  Cd Length: 460  Bit Score: 42.86  E-value: 5.36e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096   1 MTKQNIVVVGAGYAGVSATKFLAKKFKKdtdvtITLIDRHSYHT------------------MMTELHEVAGGRVEPEAI 62
Cdd:PRK06292   1 MEKYDVIVIGAGPAGYVAARRAAKLGKK-----VALIEKGPLGGtclnvgcipskaliaaaeAFHEAKHAEEFGIHADGP 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096  63 QYDLQRLFSRKKNV--KLVTDTVTGIDKENKVvKTLAGS---------------YPFDQLILGMGGE-PNdfgTPGV-KE 123
Cdd:PRK06292  76 KIDFKKVMARVRRErdRFVGGVVEGLEKKPKI-DKIKGTarfvdpntvevngerIEAKNIVIATGSRvPP---IPGVwLI 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096 124 NGFTLWSFDDAVKIRhhieatvakaaiepdaEVRKAMltfVVCGSGFTGIEM--------Vgelidwkdrlakdakidpd 195
Cdd:PRK06292 152 LGDRLLTSDDAFELD----------------KLPKSL---AVIGGGVIGLELgqalsrlgV------------------- 193

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096 196 EITlmVVEAMPTILNMLSRNDAAKAERYLEKKnVQLLLNSPIVEVAadhiklKDGSEVPTHTLIWTAGVKATSDA----- 270
Cdd:PRK06292 194 KVT--VFERGDRILPLEDPEVSKQAQKILSKE-FKIKLGAKVTSVE------KSGDEKVEELEKGGKTETIEADYvlvat 264

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096 271 ------ADFGLEAA------RGsRLVANEYMQAKgyeDKNIYIIGDLvyyeeTPNTPtpqIVQAAEQTGHTAAANIVADI 338
Cdd:PRK06292 265 grrpntDGLGLENTgieldeRG-RPVVDEHTQTS---VPGIYAAGDV-----NGKPP---LLHEAADEGRIAAENAAGDV 332


                 ...
gi 315026096 339 KGG 341
Cdd:PRK06292 333 AGG 335
PRK09564 PRK09564
coenzyme A disulfide reductase; Reviewed
 3-114 1.11e-03

coenzyme A disulfide reductase; Reviewed


Pssm-ID: 181958 [Multi-domain]  Cd Length: 444  Bit Score: 41.95  E-value: 1.11e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315026096   3 KQNIVVVGAGYAGVSATKfLAKKFKKDTDVtITLIDRhsyhtmmtelheVAGGRVEPEAIQYDLQRLfsRKKNVKLVTD- 81
Cdd:PRK09564 149 IKNIVIIGAGFIGLEAVE-AAKHLGKNVRI-IQLEDR------------ILPDSFDKEITDVMEEEL--RENGVELHLNe 212

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 315026096  82 TVTGIDKENKV--VKTLAGSYPFDQLILGMGGEPN 114
Cdd:PRK09564 213 FVKSLIGEDKVegVVTDKGEYEADVVIVATGVKPN 247
NptA COG1283
Na+/phosphate symporter [Inorganic ion transport and metabolism];
543-596 6.49e-03

Na+/phosphate symporter [Inorganic ion transport and metabolism];


Pssm-ID: 440894 [Multi-domain]  Cd Length: 540  Bit Score: 39.39  E-value: 6.49e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 315026096 543 MKFMMPNQEVALFMQKFMTIVevcIALALIAGLFTWL--SSAATIGLTIAFCLSGM 596
Cdd:COG1283  154 MEPLRDSPAFRALLASLSGNP---LLGVLVGALLTALvqSSSATVGLLLALAAQGL 206
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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