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Conserved domains on  [gi|323309753|gb|EGA62959|]
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Spc19p [Saccharomyces cerevisiae FostersO]

Protein Classification

DASH complex subunit SPC19( domain architecture ID 10550631)

DASH complex subunit SPC19 is a component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DASH_Spc19 pfam08287
Spc19; Spc19 is a component of the DASH complex. The DASH complex associates with the spindle ...
 6-129 5.32e-26

Spc19; Spc19 is a component of the DASH complex. The DASH complex associates with the spindle pole body and is important for spindle and kinetochore integrity during cell division.


:

Pssm-ID: 429900 [Multi-domain]  Cd Length: 148  Bit Score: 96.16  E-value: 5.32e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323309753    6 EQSVLALEGTVSVLKDSVESLKCANEPSTNLaSTMLQTKRVFRLVPEYDVERSKLDLIEEVEPLVRTLGDKLRKSMGRMQ 85
Cdd:pfam08287   1 ENCVSSLRSSVSLLQSSIETLDSGTSDFPRL-TKVLKTTRHFELVPEPDLEAAKASLREEIEPQIDELLDKAEKSLEKLE 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 323309753   86 RELDTLQQTYELNDLRLKKNiSMDDDDALNSPDMGQEYEGRDAD 129
Cdd:pfam08287  80 RREETLKAKLELNEGRLSNA-ESSARDEEGSQESDEEVNSSEGD 122
 
Name Accession Description Interval E-value
DASH_Spc19 pfam08287
Spc19; Spc19 is a component of the DASH complex. The DASH complex associates with the spindle ...
 6-129 5.32e-26

Spc19; Spc19 is a component of the DASH complex. The DASH complex associates with the spindle pole body and is important for spindle and kinetochore integrity during cell division.


Pssm-ID: 429900 [Multi-domain]  Cd Length: 148  Bit Score: 96.16  E-value: 5.32e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323309753    6 EQSVLALEGTVSVLKDSVESLKCANEPSTNLaSTMLQTKRVFRLVPEYDVERSKLDLIEEVEPLVRTLGDKLRKSMGRMQ 85
Cdd:pfam08287   1 ENCVSSLRSSVSLLQSSIETLDSGTSDFPRL-TKVLKTTRHFELVPEPDLEAAKASLREEIEPQIDELLDKAEKSLEKLE 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 323309753   86 RELDTLQQTYELNDLRLKKNiSMDDDDALNSPDMGQEYEGRDAD 129
Cdd:pfam08287  80 RREETLKAKLELNEGRLSNA-ESSARDEEGSQESDEEVNSSEGD 122
 
Name Accession Description Interval E-value
DASH_Spc19 pfam08287
Spc19; Spc19 is a component of the DASH complex. The DASH complex associates with the spindle ...
 6-129 5.32e-26

Spc19; Spc19 is a component of the DASH complex. The DASH complex associates with the spindle pole body and is important for spindle and kinetochore integrity during cell division.


Pssm-ID: 429900 [Multi-domain]  Cd Length: 148  Bit Score: 96.16  E-value: 5.32e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 323309753    6 EQSVLALEGTVSVLKDSVESLKCANEPSTNLaSTMLQTKRVFRLVPEYDVERSKLDLIEEVEPLVRTLGDKLRKSMGRMQ 85
Cdd:pfam08287   1 ENCVSSLRSSVSLLQSSIETLDSGTSDFPRL-TKVLKTTRHFELVPEPDLEAAKASLREEIEPQIDELLDKAEKSLEKLE 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 323309753   86 RELDTLQQTYELNDLRLKKNiSMDDDDALNSPDMGQEYEGRDAD 129
Cdd:pfam08287  80 RREETLKAKLELNEGRLSNA-ESSARDEEGSQESDEEVNSSEGD 122
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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