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Concise Results
Standard Results
Full Results
urocanate hydratase [Streptococcus sanguinis SK353]
Protein Classification
HutU family protein ( domain architecture ID 10006832 )
HutU family protein
List of domain hits
Name
Accession
Description
Interval
E-value
HutU
COG2987 Urocanate hydratase [Amino acid transport and metabolism];
73-667
0e+00
Urocanate hydratase [Amino acid transport and metabolism];
Pssm-ID: 442226 [Multi-domain]
Cd Length: 567
Bit Score: 1018.11
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 73 LK T H GRIYGYR W RP KER I YGK P IH E YKGNCTAAK A MQV M ID NNL SF E I A LY P Y ELV T YG E TG SVCA NW M QY N LI K KYL EI 152
Cdd:COG2987 1 MT T Y GRIYGYR F RP ERE I RAP P GT E LPAKGWQQE A ALR M LM NNL DP E V A EH P E ELV V YG G TG RAAR NW A QY D LI V KYL KE 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 153 MT D HQ TL V V E SG H P L G L F KSK P E APRV I I T N GL LV GEYD N MK D W E IA E EM G V T N YGQMTAG G W M YIGPQGIV H GT FN T LL 232
Cdd:COG2987 81 LE D DE TL L V Q SG K P V G V F RTH P D APRV L I A N SN LV PNWA N WE D F E EL E AL G L T M YGQMTAG S W I YIGPQGIV Q GT YE T FA 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 233 NA G R LKL G vadd GDL T GKLF ISS GLGGM S GAQ GK AA EI A KA V AIV AEVD Q SRIE T R HS QG WISQL A ESPK EA IEL A QK A L 312
Cdd:COG2987 161 NA A R KHF G ---- GDL A GKLF LTA GLGGM G GAQ PL AA TM A GG V GLI AEVD P SRIE K R LE QG YLDEV A DDLD EA LAR A KE A K 236
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 313 ETG E ST SI AYH GN IV D L L EYVNENN I HV DL LS DQTS C H NVYD g GY C PAG I SFEE RTR L L AED K E T F AK LV DQTLE RH FK A 392
Cdd:COG2987 237 AKK E PL SI GLL GN AA D V L PELVRRG I VP DL VT DQTS A H DPLN - GY L PAG L SFEE ANE L R AED P E E F KE LV KESMA RH VE A 315
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 393 IKTLTNN G T YFFDYGN AFMKAV YD S G I keiskngfdd KD G F IW P SY V EDIMG P M l F D YG Y GPFRWV C LSG KH ED LVA TD H 472
Cdd:COG2987 316 MLEFQAR G A YFFDYGN NIRQEA YD A G V ---------- KD A F DF P GF V PAYIR P L - F C YG K GPFRWV A LSG DP ED IYK TD E 384
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 473 AA M E VI d P nrry QDRD NYN WIR D A EK N Q L VV G TQ ARI LYQDCMG R VN IAL K FNE L VR E G KI - G P VM IGRDH H DV SGTD SP 551
Cdd:COG2987 385 AA L E LF - P ---- QDRD LHR WIR M A RE N V L FQ G LP ARI CWLGYGE R AK IAL A FNE M VR K G EL k A P IV IGRDH L DV GSVA SP 459
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 552 F RET S N I KDGS NVTC D MAVQCYA GN A ARG MSL V A LH N GGG T GIG KA I NG GF GL V L DGSE RI DE II K SAIAW D TIG GVAR R 631
Cdd:COG2987 460 N RET E N M KDGS DAVA D WPLLNAL GN T ARG ATW V S LH H GGG V GIG YS I HA GF VI V A DGSE EA DE RL K RVLTN D PGM GVAR H 539
570 580 590
....*....|....*....|....*....|....*.
gi 324990246 632 NW A RN E H AIETA I E Y nrlhqgtd HI T I P Y L T D ED L V 667
Cdd:COG2987 540 AD A GY E E AIETA K E R -------- GV T L P M L V D DE L L 567
Name
Accession
Description
Interval
E-value
HutU
COG2987 Urocanate hydratase [Amino acid transport and metabolism];
73-667
0e+00
Urocanate hydratase [Amino acid transport and metabolism];
Pssm-ID: 442226 [Multi-domain]
Cd Length: 567
Bit Score: 1018.11
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 73 LK T H GRIYGYR W RP KER I YGK P IH E YKGNCTAAK A MQV M ID NNL SF E I A LY P Y ELV T YG E TG SVCA NW M QY N LI K KYL EI 152
Cdd:COG2987 1 MT T Y GRIYGYR F RP ERE I RAP P GT E LPAKGWQQE A ALR M LM NNL DP E V A EH P E ELV V YG G TG RAAR NW A QY D LI V KYL KE 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 153 MT D HQ TL V V E SG H P L G L F KSK P E APRV I I T N GL LV GEYD N MK D W E IA E EM G V T N YGQMTAG G W M YIGPQGIV H GT FN T LL 232
Cdd:COG2987 81 LE D DE TL L V Q SG K P V G V F RTH P D APRV L I A N SN LV PNWA N WE D F E EL E AL G L T M YGQMTAG S W I YIGPQGIV Q GT YE T FA 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 233 NA G R LKL G vadd GDL T GKLF ISS GLGGM S GAQ GK AA EI A KA V AIV AEVD Q SRIE T R HS QG WISQL A ESPK EA IEL A QK A L 312
Cdd:COG2987 161 NA A R KHF G ---- GDL A GKLF LTA GLGGM G GAQ PL AA TM A GG V GLI AEVD P SRIE K R LE QG YLDEV A DDLD EA LAR A KE A K 236
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 313 ETG E ST SI AYH GN IV D L L EYVNENN I HV DL LS DQTS C H NVYD g GY C PAG I SFEE RTR L L AED K E T F AK LV DQTLE RH FK A 392
Cdd:COG2987 237 AKK E PL SI GLL GN AA D V L PELVRRG I VP DL VT DQTS A H DPLN - GY L PAG L SFEE ANE L R AED P E E F KE LV KESMA RH VE A 315
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 393 IKTLTNN G T YFFDYGN AFMKAV YD S G I keiskngfdd KD G F IW P SY V EDIMG P M l F D YG Y GPFRWV C LSG KH ED LVA TD H 472
Cdd:COG2987 316 MLEFQAR G A YFFDYGN NIRQEA YD A G V ---------- KD A F DF P GF V PAYIR P L - F C YG K GPFRWV A LSG DP ED IYK TD E 384
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 473 AA M E VI d P nrry QDRD NYN WIR D A EK N Q L VV G TQ ARI LYQDCMG R VN IAL K FNE L VR E G KI - G P VM IGRDH H DV SGTD SP 551
Cdd:COG2987 385 AA L E LF - P ---- QDRD LHR WIR M A RE N V L FQ G LP ARI CWLGYGE R AK IAL A FNE M VR K G EL k A P IV IGRDH L DV GSVA SP 459
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 552 F RET S N I KDGS NVTC D MAVQCYA GN A ARG MSL V A LH N GGG T GIG KA I NG GF GL V L DGSE RI DE II K SAIAW D TIG GVAR R 631
Cdd:COG2987 460 N RET E N M KDGS DAVA D WPLLNAL GN T ARG ATW V S LH H GGG V GIG YS I HA GF VI V A DGSE EA DE RL K RVLTN D PGM GVAR H 539
570 580 590
....*....|....*....|....*....|....*.
gi 324990246 632 NW A RN E H AIETA I E Y nrlhqgtd HI T I P Y L T D ED L V 667
Cdd:COG2987 540 AD A GY E E AIETA K E R -------- GV T L P M L V D DE L L 567
PRK05414
PRK05414 urocanate hydratase; Provisional
79-662
0e+00
urocanate hydratase; Provisional
Pssm-ID: 235448 [Multi-domain]
Cd Length: 556
Bit Score: 925.69
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 79 IYGYR W RP KER I YGKPIH E YKGNCTAAK A MQV M ID NNL SF E I A LY P Y ELV T YG ET G SVCA NW MQ Y NL I K K Y L EIMT D HQ T 158
Cdd:PRK05414 1 IYGYR F RP ERE I RAPRGT E LTAKGWLQE A ALR M LM NNL DP E V A ER P E ELV V YG GI G RAAR NW EC Y DA I V K T L KELE D DE T 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 159 L V V E SG H P L G L FK SK P E APRV I I T N GL LV GEYD N MKDWEIA E EM G V T N YGQMTAG G W M YIG P QGIV H GT FN T LLN A G R LK 238
Cdd:PRK05414 81 L L V Q SG K P V G V FK TH P D APRV L I A N SN LV PHWA N WEHFNEL E AK G L T M YGQMTAG S W I YIG S QGIV Q GT YE T FAE A A R QH 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 239 L G vadd GDL T G K L FISS GLGGM S GAQ GK AA EI A K AV AIVA EVD Q SRI ET R HSQ G WISQL A ESPK EA IE LA QK A LET GE ST 318
Cdd:PRK05414 161 F G ---- GDL A G R L VLTA GLGGM G GAQ PL AA TM A G AV CLAV EVD E SRI DK R LRT G YLDEK A DDLD EA LA LA EE A KAA GE PL 236
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 319 SI AYH GN IV D L L EYVNENN I HV DL LS DQTS C H NVYD g GY C P A G ISF EE RTR L L AED K E T F A K LVDQTLE RH FK A IKTLTN 398
Cdd:PRK05414 237 SI GLL GN AA D V L PELVRRG I RP DL VT DQTS A H DPLN - GY L P V G WTL EE AAE L R AED P E E F V K AAKASMA RH VE A MLAFQA 315
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 399 N G T Y F FDYGN AFMKAVY D S G I keiskngfdd KDG F IW P SY V EDIMG P m LF DY G Y GPFRWV C LSG KH ED LVA TD H A AM E VI 478
Cdd:PRK05414 316 R G A Y V FDYGN NIRQMAF D A G V ---------- ENA F DF P GF V PAYIR P - LF CE G K GPFRWV A LSG DP ED IYK TD A A VK E LF 384
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 479 D pnrry Q D RDNYN WI RD A EKNQ L VV G TQ ARI LYQDCMG R VNIA L K FNE L VR E G KI - G P VM IGRDH H D VSGTD SP F RET SN 557
Cdd:PRK05414 385 P ----- D D EHLHR WI DM A RERI L FQ G LP ARI CWLGYGE R ARLG L A FNE M VR N G EL k A P IV IGRDH L D SGSVA SP N RET EA 459
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 558 I KDGS NVTC D MAVQCYAG N A A R G MSL V A LH N GGG T G I G KA I NG GF GL V L DG S E RID E IIKSAIAW D TIG GV A R RNW A RN E 637
Cdd:PRK05414 460 M KDGS DAVA D WPLLNALL N T A S G ATW V S LH H GGG V G M G YS I HA GF VI V A DG T E EAA E RLERVLTN D PAT GV M R HAD A GY E 539
570 580
....*....|....*....|....*
gi 324990246 638 H AIETA I E ynrlhqgt DH IT I P Y L T 662
Cdd:PRK05414 540 I AIETA K E -------- KG IT L P M L A 556
hutU
TIGR01228 urocanate hydratase; This model represents the second of four enzymes involved in the ...
93-645
5.51e-139
urocanate hydratase; This model represents the second of four enzymes involved in the degradation of histidine to glutamate. [Energy metabolism, Amino acids and amines]
Pssm-ID: 130295
Cd Length: 545
Bit Score: 417.70
E-value: 5.51e-139
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 93 KP I HEYK G NCTAA K ----- A MQV M ID NNL SF E I A LY P YE LV T YG ET G SVCA NW MQYNL I KKY L EIMTDHQ TL V V E SG H P L 167
Cdd:TIGR01228 1 RE I RAPR G TKLEC K gwlqe A ALR M LM NNL DP E V A ED P EN LV V YG GI G KAAR NW EAFDK I VET L KRLENDE TL L V Q SG K P V 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 168 G L FK SKPE APRV I I T N GL LV GEY dnm K DWE IAE E M --- G VTN YGQMTAG G W M YIG P QGI VH GT FN T LLNAG R LKL G vadd 244
Cdd:TIGR01228 81 G V FK THEN APRV L I A N SN LV PHW --- A DWE HFH E L eak G LMM YGQMTAG S W I YIG T QGI LQ GT YE T FAELA R QHF G ---- 153
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 245 G D L T GK LFISS GLGGM S GAQ GK A AEIAKA V A I VA EVD Q SRI ET R HSQGWISQLAE S PK EA IEL A QK A LET G EST SI AYH G 324
Cdd:TIGR01228 154 G S L K GK WVLTA GLGGM G GAQ PL A VTMNGG V S I AV EVD E SRI DK R LETKYCDEQTD S LD EA LAR A EE A KAE G KPI SI GLL G 233
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 325 N IVDL L EYVNENNIHV D LLS DQTS C H NVY d G GY C P A G ISF E ERTR L LA E DK E TFA K LVD Q TLER H FK A IKTLTNN G TYF F 404
Cdd:TIGR01228 234 N AAEV L PELLKRGVVP D VVT DQTS A H DPL - N GY I P E G YTV E DADK L RQ E EP E AYV K AAK Q SMAK H VR A MLAFQKQ G SVT F 312
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 405 DYGN AFMKAVYDS G ikei SKNG F d D KD GF I w P S Y VED imgpm LF DY G Y GPFRWV C LSG KHE D LVA TD H A AM E VIDPNRRY 484
Cdd:TIGR01228 313 DYGN NIRQVAKEE G ---- VEDA F - D FP GF V - P A Y IRP ----- LF CR G K GPFRWV A LSG DPA D IYR TD A A VK E LFPEDAHL 381
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 485 Q drdny N WI RD A EKNQLVV G TQ ARI LYQDCMG R VNIA L KF NE L VR E G KI - G PV M IGRDH H D VSGTD SP F RET SNI KDGS N 563
Cdd:TIGR01228 382 H ----- R WI DM A QERVSFQ G LP ARI CWLGYGE R AKLG L AI NE M VR S G EL k A PV V IGRDH L D AGSVA SP N RET EAM KDGS D 456
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 564 VTC D MAVQCYAG N A A R G MSL V AL H N GGG T G I G KAING G FGL V L DG SERID E I I KSAIAW D TIG GV A R RNW A RN E H AI ET A 643
Cdd:TIGR01228 457 AVS D WPLLNALL N T A A G ATW V SF H H GGG V G M G FSLHA G MVI V A DG TDEAA E R I ARVLTN D PGM GV I R HAD A GY E I AI DV A 536
..
gi 324990246 644 I E 645
Cdd:TIGR01228 537 K E 538
Urocanase_C
pfam17392 Urocanase C-terminal domain;
447-645
2.80e-112
Urocanase C-terminal domain;
Pssm-ID: 465414 [Multi-domain]
Cd Length: 196
Bit Score: 336.00
E-value: 2.80e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 447 LF DY G Y GPFRWV C LSG KH ED LVA TD H AA M E VI dpnrr Y QD R D NYN WI RD A EK N Q L VV G TQ ARI L Y QDCMG R VN IAL K FNE 526
Cdd:pfam17392 2 LF CE G F GPFRWV A LSG DP ED IYR TD E AA L E LF ----- P QD E D LIR WI KL A RE N V L FQ G LP ARI C Y LGYGE R AK IAL A FNE 76
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 527 LVREG K I - G P VM IGRDH H DV SGTD SPFRET S N I KDGS NVTC D MAVQCYA GNAARG MSL V A LHNGGG T GIG KA I NG GFG L V 605
Cdd:pfam17392 77 LVREG E I s A P IV IGRDH L DV GSVA SPFRET E N M KDGS DAIA D WPLLNAL GNAARG ATW V S LHNGGG V GIG YS I HA GFG M V 156
170 180 190 200
....*....|....*....|....*....|....*....|
gi 324990246 606 L DG S E RI DE IIKSAIA WD TIG GVAR RNW A RN E H AI ET A IE 645
Cdd:pfam17392 157 A DG T E EA DE RLRRVLT WD PGN GVAR HAD A GY E E AI DV A RR 196
Name
Accession
Description
Interval
E-value
HutU
COG2987 Urocanate hydratase [Amino acid transport and metabolism];
73-667
0e+00
Urocanate hydratase [Amino acid transport and metabolism];
Pssm-ID: 442226 [Multi-domain]
Cd Length: 567
Bit Score: 1018.11
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 73 LK T H GRIYGYR W RP KER I YGK P IH E YKGNCTAAK A MQV M ID NNL SF E I A LY P Y ELV T YG E TG SVCA NW M QY N LI K KYL EI 152
Cdd:COG2987 1 MT T Y GRIYGYR F RP ERE I RAP P GT E LPAKGWQQE A ALR M LM NNL DP E V A EH P E ELV V YG G TG RAAR NW A QY D LI V KYL KE 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 153 MT D HQ TL V V E SG H P L G L F KSK P E APRV I I T N GL LV GEYD N MK D W E IA E EM G V T N YGQMTAG G W M YIGPQGIV H GT FN T LL 232
Cdd:COG2987 81 LE D DE TL L V Q SG K P V G V F RTH P D APRV L I A N SN LV PNWA N WE D F E EL E AL G L T M YGQMTAG S W I YIGPQGIV Q GT YE T FA 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 233 NA G R LKL G vadd GDL T GKLF ISS GLGGM S GAQ GK AA EI A KA V AIV AEVD Q SRIE T R HS QG WISQL A ESPK EA IEL A QK A L 312
Cdd:COG2987 161 NA A R KHF G ---- GDL A GKLF LTA GLGGM G GAQ PL AA TM A GG V GLI AEVD P SRIE K R LE QG YLDEV A DDLD EA LAR A KE A K 236
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 313 ETG E ST SI AYH GN IV D L L EYVNENN I HV DL LS DQTS C H NVYD g GY C PAG I SFEE RTR L L AED K E T F AK LV DQTLE RH FK A 392
Cdd:COG2987 237 AKK E PL SI GLL GN AA D V L PELVRRG I VP DL VT DQTS A H DPLN - GY L PAG L SFEE ANE L R AED P E E F KE LV KESMA RH VE A 315
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 393 IKTLTNN G T YFFDYGN AFMKAV YD S G I keiskngfdd KD G F IW P SY V EDIMG P M l F D YG Y GPFRWV C LSG KH ED LVA TD H 472
Cdd:COG2987 316 MLEFQAR G A YFFDYGN NIRQEA YD A G V ---------- KD A F DF P GF V PAYIR P L - F C YG K GPFRWV A LSG DP ED IYK TD E 384
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 473 AA M E VI d P nrry QDRD NYN WIR D A EK N Q L VV G TQ ARI LYQDCMG R VN IAL K FNE L VR E G KI - G P VM IGRDH H DV SGTD SP 551
Cdd:COG2987 385 AA L E LF - P ---- QDRD LHR WIR M A RE N V L FQ G LP ARI CWLGYGE R AK IAL A FNE M VR K G EL k A P IV IGRDH L DV GSVA SP 459
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 552 F RET S N I KDGS NVTC D MAVQCYA GN A ARG MSL V A LH N GGG T GIG KA I NG GF GL V L DGSE RI DE II K SAIAW D TIG GVAR R 631
Cdd:COG2987 460 N RET E N M KDGS DAVA D WPLLNAL GN T ARG ATW V S LH H GGG V GIG YS I HA GF VI V A DGSE EA DE RL K RVLTN D PGM GVAR H 539
570 580 590
....*....|....*....|....*....|....*.
gi 324990246 632 NW A RN E H AIETA I E Y nrlhqgtd HI T I P Y L T D ED L V 667
Cdd:COG2987 540 AD A GY E E AIETA K E R -------- GV T L P M L V D DE L L 567
PRK05414
PRK05414 urocanate hydratase; Provisional
79-662
0e+00
urocanate hydratase; Provisional
Pssm-ID: 235448 [Multi-domain]
Cd Length: 556
Bit Score: 925.69
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 79 IYGYR W RP KER I YGKPIH E YKGNCTAAK A MQV M ID NNL SF E I A LY P Y ELV T YG ET G SVCA NW MQ Y NL I K K Y L EIMT D HQ T 158
Cdd:PRK05414 1 IYGYR F RP ERE I RAPRGT E LTAKGWLQE A ALR M LM NNL DP E V A ER P E ELV V YG GI G RAAR NW EC Y DA I V K T L KELE D DE T 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 159 L V V E SG H P L G L FK SK P E APRV I I T N GL LV GEYD N MKDWEIA E EM G V T N YGQMTAG G W M YIG P QGIV H GT FN T LLN A G R LK 238
Cdd:PRK05414 81 L L V Q SG K P V G V FK TH P D APRV L I A N SN LV PHWA N WEHFNEL E AK G L T M YGQMTAG S W I YIG S QGIV Q GT YE T FAE A A R QH 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 239 L G vadd GDL T G K L FISS GLGGM S GAQ GK AA EI A K AV AIVA EVD Q SRI ET R HSQ G WISQL A ESPK EA IE LA QK A LET GE ST 318
Cdd:PRK05414 161 F G ---- GDL A G R L VLTA GLGGM G GAQ PL AA TM A G AV CLAV EVD E SRI DK R LRT G YLDEK A DDLD EA LA LA EE A KAA GE PL 236
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 319 SI AYH GN IV D L L EYVNENN I HV DL LS DQTS C H NVYD g GY C P A G ISF EE RTR L L AED K E T F A K LVDQTLE RH FK A IKTLTN 398
Cdd:PRK05414 237 SI GLL GN AA D V L PELVRRG I RP DL VT DQTS A H DPLN - GY L P V G WTL EE AAE L R AED P E E F V K AAKASMA RH VE A MLAFQA 315
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 399 N G T Y F FDYGN AFMKAVY D S G I keiskngfdd KDG F IW P SY V EDIMG P m LF DY G Y GPFRWV C LSG KH ED LVA TD H A AM E VI 478
Cdd:PRK05414 316 R G A Y V FDYGN NIRQMAF D A G V ---------- ENA F DF P GF V PAYIR P - LF CE G K GPFRWV A LSG DP ED IYK TD A A VK E LF 384
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 479 D pnrry Q D RDNYN WI RD A EKNQ L VV G TQ ARI LYQDCMG R VNIA L K FNE L VR E G KI - G P VM IGRDH H D VSGTD SP F RET SN 557
Cdd:PRK05414 385 P ----- D D EHLHR WI DM A RERI L FQ G LP ARI CWLGYGE R ARLG L A FNE M VR N G EL k A P IV IGRDH L D SGSVA SP N RET EA 459
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 558 I KDGS NVTC D MAVQCYAG N A A R G MSL V A LH N GGG T G I G KA I NG GF GL V L DG S E RID E IIKSAIAW D TIG GV A R RNW A RN E 637
Cdd:PRK05414 460 M KDGS DAVA D WPLLNALL N T A S G ATW V S LH H GGG V G M G YS I HA GF VI V A DG T E EAA E RLERVLTN D PAT GV M R HAD A GY E 539
570 580
....*....|....*....|....*
gi 324990246 638 H AIETA I E ynrlhqgt DH IT I P Y L T 662
Cdd:PRK05414 540 I AIETA K E -------- KG IT L P M L A 556
hutU
TIGR01228 urocanate hydratase; This model represents the second of four enzymes involved in the ...
93-645
5.51e-139
urocanate hydratase; This model represents the second of four enzymes involved in the degradation of histidine to glutamate. [Energy metabolism, Amino acids and amines]
Pssm-ID: 130295
Cd Length: 545
Bit Score: 417.70
E-value: 5.51e-139
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 93 KP I HEYK G NCTAA K ----- A MQV M ID NNL SF E I A LY P YE LV T YG ET G SVCA NW MQYNL I KKY L EIMTDHQ TL V V E SG H P L 167
Cdd:TIGR01228 1 RE I RAPR G TKLEC K gwlqe A ALR M LM NNL DP E V A ED P EN LV V YG GI G KAAR NW EAFDK I VET L KRLENDE TL L V Q SG K P V 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 168 G L FK SKPE APRV I I T N GL LV GEY dnm K DWE IAE E M --- G VTN YGQMTAG G W M YIG P QGI VH GT FN T LLNAG R LKL G vadd 244
Cdd:TIGR01228 81 G V FK THEN APRV L I A N SN LV PHW --- A DWE HFH E L eak G LMM YGQMTAG S W I YIG T QGI LQ GT YE T FAELA R QHF G ---- 153
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 245 G D L T GK LFISS GLGGM S GAQ GK A AEIAKA V A I VA EVD Q SRI ET R HSQGWISQLAE S PK EA IEL A QK A LET G EST SI AYH G 324
Cdd:TIGR01228 154 G S L K GK WVLTA GLGGM G GAQ PL A VTMNGG V S I AV EVD E SRI DK R LETKYCDEQTD S LD EA LAR A EE A KAE G KPI SI GLL G 233
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 325 N IVDL L EYVNENNIHV D LLS DQTS C H NVY d G GY C P A G ISF E ERTR L LA E DK E TFA K LVD Q TLER H FK A IKTLTNN G TYF F 404
Cdd:TIGR01228 234 N AAEV L PELLKRGVVP D VVT DQTS A H DPL - N GY I P E G YTV E DADK L RQ E EP E AYV K AAK Q SMAK H VR A MLAFQKQ G SVT F 312
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 405 DYGN AFMKAVYDS G ikei SKNG F d D KD GF I w P S Y VED imgpm LF DY G Y GPFRWV C LSG KHE D LVA TD H A AM E VIDPNRRY 484
Cdd:TIGR01228 313 DYGN NIRQVAKEE G ---- VEDA F - D FP GF V - P A Y IRP ----- LF CR G K GPFRWV A LSG DPA D IYR TD A A VK E LFPEDAHL 381
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 485 Q drdny N WI RD A EKNQLVV G TQ ARI LYQDCMG R VNIA L KF NE L VR E G KI - G PV M IGRDH H D VSGTD SP F RET SNI KDGS N 563
Cdd:TIGR01228 382 H ----- R WI DM A QERVSFQ G LP ARI CWLGYGE R AKLG L AI NE M VR S G EL k A PV V IGRDH L D AGSVA SP N RET EAM KDGS D 456
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 564 VTC D MAVQCYAG N A A R G MSL V AL H N GGG T G I G KAING G FGL V L DG SERID E I I KSAIAW D TIG GV A R RNW A RN E H AI ET A 643
Cdd:TIGR01228 457 AVS D WPLLNALL N T A A G ATW V SF H H GGG V G M G FSLHA G MVI V A DG TDEAA E R I ARVLTN D PGM GV I R HAD A GY E I AI DV A 536
..
gi 324990246 644 I E 645
Cdd:TIGR01228 537 K E 538
Urocanase_C
pfam17392 Urocanase C-terminal domain;
447-645
2.80e-112
Urocanase C-terminal domain;
Pssm-ID: 465414 [Multi-domain]
Cd Length: 196
Bit Score: 336.00
E-value: 2.80e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 447 LF DY G Y GPFRWV C LSG KH ED LVA TD H AA M E VI dpnrr Y QD R D NYN WI RD A EK N Q L VV G TQ ARI L Y QDCMG R VN IAL K FNE 526
Cdd:pfam17392 2 LF CE G F GPFRWV A LSG DP ED IYR TD E AA L E LF ----- P QD E D LIR WI KL A RE N V L FQ G LP ARI C Y LGYGE R AK IAL A FNE 76
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 527 LVREG K I - G P VM IGRDH H DV SGTD SPFRET S N I KDGS NVTC D MAVQCYA GNAARG MSL V A LHNGGG T GIG KA I NG GFG L V 605
Cdd:pfam17392 77 LVREG E I s A P IV IGRDH L DV GSVA SPFRET E N M KDGS DAIA D WPLLNAL GNAARG ATW V S LHNGGG V GIG YS I HA GFG M V 156
170 180 190 200
....*....|....*....|....*....|....*....|
gi 324990246 606 L DG S E RI DE IIKSAIA WD TIG GVAR RNW A RN E H AI ET A IE 645
Cdd:pfam17392 157 A DG T E EA DE RLRRVLT WD PGN GVAR HAD A GY E E AI DV A RR 196
Urocanase
pfam01175 Urocanase Rossmann-like domain;
219-442
4.50e-108
Urocanase Rossmann-like domain;
Pssm-ID: 460098 [Multi-domain]
Cd Length: 209
Bit Score: 325.52
E-value: 4.50e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 219 G P QGIV H GT FN T LLN A G R LKL G vadd GDL T GKLF ISS GLGGM S GAQ GK AA EI A KA V AI V A EVD Q SRIE T R HS QG WISQL A 298
Cdd:pfam01175 1 G T QGIV Q GT YE T FAA A A R KHF G ---- GDL A GKLF VTA GLGGM G GAQ PL AA TM A GG V GL V V EVD P SRIE K R LE QG YLDEV A 76
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 299 ESPK EA IEL A QK A LETG E ST SI AYH GN IV D L LE YVNENN I HV DL LS DQTS C H NVYD g GY C PAG IS FEE RTR L LA ED K E TF 378
Cdd:pfam01175 77 DDLD EA LAR A KE A KAEK E PL SI GLL GN AA D V LE ELVRRG I IP DL VT DQTS A H DPLN - GY I PAG LT FEE ANE L RK ED P E KY 155
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 324990246 379 AK LV DQTLE RH FK A IKT L TNN G T YFFDYGN A F MKAVY D S G I keiskngfdd KDG F IW P SY V EDI 442
Cdd:pfam01175 156 KE LV QESMA RH VE A MLA L QAR G A YFFDYGN N F RLEAK D A G V ---------- DGA F DF P GF V PAY 209
Urocanase_N
pfam17391 Urocanase N-terminal domain;
90-216
1.03e-68
Urocanase N-terminal domain;
Pssm-ID: 465413 [Multi-domain]
Cd Length: 127
Bit Score: 220.11
E-value: 1.03e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324990246 90 I YGKPIH E YKGNCTAAK A MQV M ID NNL SF E I A L YP Y ELV T YG ET G SVCA NW M Q YN LI K KYL EIMTDH QTL V V E SG H P L GL 169
Cdd:pfam17391 1 I RAPRGT E LPCKGWQQE A ALR M LM NNL DP E V A E YP E ELV V YG GN G KAAR NW A Q FD LI V KYL KELEED QTL L V Q SG K P V GL 80
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 324990246 170 F KSK P E APRV I I T N GL LV GEYDNMK D W E IA E EM G V T N YGQMTAG G W M 216
Cdd:pfam17391 81 F RTH P D APRV L I A N SN LV PNWATWE D F E RL E AL G L T M YGQMTAG S W I 127
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
