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Conserved domains on  [gi|327549354|gb|EGF33925|]
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hypothetical protein IMCC9480_3851 [Oxalobacteraceae bacterium IMCC9480]

Protein Classification

STAS and STAS_2 domain-containing protein( domain architecture ID 10228318)

STAS and STAS_2 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MlaB COG3113
Binding protein subunit MlaB of the ABC-type intermembrane phospholipid transporter Mla, ...
 151-227 8.04e-06

Binding protein subunit MlaB of the ABC-type intermembrane phospholipid transporter Mla, contains STAS domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442347 [Multi-domain]  Cd Length: 97  Bit Score: 44.08  E-value: 8.04e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 327549354 151 SATTPSASAVIALSGDLD-ASIQKQLERVHKLGTSNSILQLDFTRVGTITREGCAMLLETLKQLQQAGSSVALIHASE 227
Cdd:COG3113    4 ALLWNAEGGTLRLSGELTrDTVLALWAQLLALLAAGGAVEIDLSGVTRVDSAGLALLLELLREARAQGKTLRLTGVPE 81
STAS_2 pfam13466
STAS domain; The STAS (after Sulphate Transporter and AntiSigma factor antagonist) domain is ...
 323-379 1.00e-04

STAS domain; The STAS (after Sulphate Transporter and AntiSigma factor antagonist) domain is found in the C-terminal region of Sulphate transporters and bacterial antisigma factor antagonists. It has been suggested that this domain may have a general NTP binding function.


:

Pssm-ID: 433231 [Multi-domain]  Cd Length: 80  Bit Score: 40.28  E-value: 1.00e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 327549354  323 AAQHNPAIIDCKHLARVDFSAAGQLLSCLAPLVKNDRIIELHNVNQLVTALFNVMGL 379
Cdd:pfam13466  23 LAAGSPVVVDLSGVERVDSAGLALLLALARRARARGKRLVLRGLPPALLRLLRLLGL 79
 
Name Accession Description Interval E-value
MlaB COG3113
Binding protein subunit MlaB of the ABC-type intermembrane phospholipid transporter Mla, ...
 151-227 8.04e-06

Binding protein subunit MlaB of the ABC-type intermembrane phospholipid transporter Mla, contains STAS domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442347 [Multi-domain]  Cd Length: 97  Bit Score: 44.08  E-value: 8.04e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 327549354 151 SATTPSASAVIALSGDLD-ASIQKQLERVHKLGTSNSILQLDFTRVGTITREGCAMLLETLKQLQQAGSSVALIHASE 227
Cdd:COG3113    4 ALLWNAEGGTLRLSGELTrDTVLALWAQLLALLAAGGAVEIDLSGVTRVDSAGLALLLELLREARAQGKTLRLTGVPE 81
STAS_2 pfam13466
STAS domain; The STAS (after Sulphate Transporter and AntiSigma factor antagonist) domain is ...
 323-379 1.00e-04

STAS domain; The STAS (after Sulphate Transporter and AntiSigma factor antagonist) domain is found in the C-terminal region of Sulphate transporters and bacterial antisigma factor antagonists. It has been suggested that this domain may have a general NTP binding function.


Pssm-ID: 433231 [Multi-domain]  Cd Length: 80  Bit Score: 40.28  E-value: 1.00e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 327549354  323 AAQHNPAIIDCKHLARVDFSAAGQLLSCLAPLVKNDRIIELHNVNQLVTALFNVMGL 379
Cdd:pfam13466  23 LAAGSPVVVDLSGVERVDSAGLALLLALARRARARGKRLVLRGLPPALLRLLRLLGL 79
STAS_anti-anti-sigma_factors cd07043
Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key ...
 151-235 2.03e-04

Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Anti-anti-sigma factors play an important role in the regulation of several sigma factors and their corresponding anti-sigma factors. Upon dephosphorylation they bind the anti-sigma factor and induce the release of the sigma factor from the anti-sigma factor. In a feedback mechanism the anti-anti-sigma factor can be inactivated via phosphorylation by the anti-sigma factor. Well studied examples from Bacillus subtilis are SpoIIAA (regulating sigmaF and sigmaC which play an important role in sporulation) and RsbV (regulating sigmaB involved in the general stress response). The STAS domain is also found in the C- terminal region of sulphate transporters and stressosomes.


Pssm-ID: 132914 [Multi-domain]  Cd Length: 99  Bit Score: 40.20  E-value: 2.03e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327549354 151 SATTPSASAVIALSGDLDASIQKQLERV--HKLGTSNSILQLDFTRVGTITREGCAMLLETLKQLQQAGSSVALIHaseL 228
Cdd:cd07043    2 TVEERGGVLVVRLSGELDAATAPELREAleELLAEGPRRLVLDLSGVTFIDSSGLGVLLGAYKRARAAGGRLVLVN---V 78


                 ....*..
gi 327549354 229 SDRVRAI 235
Cdd:cd07043   79 SPAVRRV 85
 
Name Accession Description Interval E-value
MlaB COG3113
Binding protein subunit MlaB of the ABC-type intermembrane phospholipid transporter Mla, ...
 151-227 8.04e-06

Binding protein subunit MlaB of the ABC-type intermembrane phospholipid transporter Mla, contains STAS domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442347 [Multi-domain]  Cd Length: 97  Bit Score: 44.08  E-value: 8.04e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 327549354 151 SATTPSASAVIALSGDLD-ASIQKQLERVHKLGTSNSILQLDFTRVGTITREGCAMLLETLKQLQQAGSSVALIHASE 227
Cdd:COG3113    4 ALLWNAEGGTLRLSGELTrDTVLALWAQLLALLAAGGAVEIDLSGVTRVDSAGLALLLELLREARAQGKTLRLTGVPE 81
STAS_2 pfam13466
STAS domain; The STAS (after Sulphate Transporter and AntiSigma factor antagonist) domain is ...
 323-379 1.00e-04

STAS domain; The STAS (after Sulphate Transporter and AntiSigma factor antagonist) domain is found in the C-terminal region of Sulphate transporters and bacterial antisigma factor antagonists. It has been suggested that this domain may have a general NTP binding function.


Pssm-ID: 433231 [Multi-domain]  Cd Length: 80  Bit Score: 40.28  E-value: 1.00e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 327549354  323 AAQHNPAIIDCKHLARVDFSAAGQLLSCLAPLVKNDRIIELHNVNQLVTALFNVMGL 379
Cdd:pfam13466  23 LAAGSPVVVDLSGVERVDSAGLALLLALARRARARGKRLVLRGLPPALLRLLRLLGL 79
SpoIIAA COG1366
Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) [Signal transduction ...
 159-227 1.06e-04

Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) [Signal transduction mechanisms];


Pssm-ID: 440977 [Multi-domain]  Cd Length: 93  Bit Score: 40.61  E-value: 1.06e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 327549354 159 AVIALSGDLDASIQKQLERV--HKLGTSNSILQLDFTRVGTITREGCAMLLETLKQLQQAGSSVALIHASE 227
Cdd:COG1366   11 LVLPLIGELDAARAPELREAllEALETGARRVVLDLSGVTFIDSSGLGALLSLAKAARLLGGRLVLVGVSP 81
STAS_anti-anti-sigma_factors cd07043
Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key ...
 151-235 2.03e-04

Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Anti-anti-sigma factors play an important role in the regulation of several sigma factors and their corresponding anti-sigma factors. Upon dephosphorylation they bind the anti-sigma factor and induce the release of the sigma factor from the anti-sigma factor. In a feedback mechanism the anti-anti-sigma factor can be inactivated via phosphorylation by the anti-sigma factor. Well studied examples from Bacillus subtilis are SpoIIAA (regulating sigmaF and sigmaC which play an important role in sporulation) and RsbV (regulating sigmaB involved in the general stress response). The STAS domain is also found in the C- terminal region of sulphate transporters and stressosomes.


Pssm-ID: 132914 [Multi-domain]  Cd Length: 99  Bit Score: 40.20  E-value: 2.03e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327549354 151 SATTPSASAVIALSGDLDASIQKQLERV--HKLGTSNSILQLDFTRVGTITREGCAMLLETLKQLQQAGSSVALIHaseL 228
Cdd:cd07043    2 TVEERGGVLVVRLSGELDAATAPELREAleELLAEGPRRLVLDLSGVTFIDSSGLGVLLGAYKRARAAGGRLVLVN---V 78


                 ....*..
gi 327549354 229 SDRVRAI 235
Cdd:cd07043   79 SPAVRRV 85
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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