|
Name |
Accession |
Description |
Interval |
E-value |
| PRK03080 |
PRK03080 |
phosphoserine transaminase; |
16-385 |
1.49e-173 |
|
phosphoserine transaminase;
Pssm-ID: 235103 Cd Length: 378 Bit Score: 488.54 E-value: 1.49e-173
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 16 MAQPMIPrDLLPSDPRFGCGPSRIRREV-VASLSepGSVMGTSHRQPPVRHVVAAIREELTELYNLPTDYEVALGNGGAT 94
Cdd:PRK03080 1 MTTLTIP-ALRPADPRFSSGPCKKRPGWqLEALA--DALLGRSHRQKPVKALLKRVIEGTRELLSLPEGYEVGIVPGSDT 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 95 LFWDMATVSLV-EKRAATGVYGEFTRKFSSALQRAPFLADPAVFQAEPGKLALPKAVSDVDTYAWAHNETSTGVVAPVRR 173
Cdd:PRK03080 78 GAWEMALWSLLgARRVDHLAWESFGSKWATDVVKQLKLEDPRVLEADYGSLPDLSAVDFDRDVVFTWNGTTTGVRVPVAR 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 174 PNDIDDNSLVLVDATSAAGGVAADMSTIDAYYFSPQKNLSSDGGLWLAILSPAAIERSNRVTsSARWVPQMLDLS---LA 250
Cdd:PRK03080 158 WIGADREGLTICDATSAAFALPLDWSKLDVYTFSWQKVLGGEGGHGMAILSPRAVERLESYT-PARPIPKFFRLTkggKA 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 251 VTNSRADQTLNTPALATLVMLEAQCRWLLDQGGMAWAASRTASTSGILYRWAEDNPLTTPFVADPALRSPVVVTIDIDE- 329
Cdd:PRK03080 237 IENSFKGQTINTPSMLTVEDYLDQLDWANSIGGLDALIARTAANASVLYDWAEKTPWATPLVADPATRSNTSVTLDFVDa 316
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 328758673 330 --SVDAARLCARARDNGILDIEPYRKlGRNQIRIATFSSIEPSDVEALTACLDWLLEN 385
Cdd:PRK03080 317 qaAVDAAAVAKLLRENGAVDIEPYRD-APNGLRIWCGPTVEPADVEALTPWLDWAFER 373
|
|
| serC_3 |
TIGR01366 |
phosphoserine aminotransferase, putative; This model represents a putative variant form of the ... |
27-384 |
1.37e-162 |
|
phosphoserine aminotransferase, putative; This model represents a putative variant form of the serine biosynthesis enzyme phosphoserine aminotransferase, as found in Mycobacterium tuberculosis and related high-GC Gram-positive bacteria. [Amino acid biosynthesis, Serine family]
Pssm-ID: 130433 Cd Length: 361 Bit Score: 460.17 E-value: 1.37e-162
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 27 PSDPRFGCGPSRIRREVVASLSEPG-SVMGTSHRQPPVRHVVAAIREELTELYNLPTDYEVALGNGGATLFWDMATVSLV 105
Cdd:TIGR01366 2 PRDGRFGSGPSKVRLEQLQALTTTAaSLFGTSHRQAPVKNLVGRVREGLAELFSLPDGYEVILGNGGATAFWDAATFGLI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 106 EKRAATGVYGEFTRKFSSALQRAPFLADPAVFQAEPGKLALPKAVSDVDTYAWAHNETSTGVVAPVRRPNDIDDnSLVLV 185
Cdd:TIGR01366 82 EKKSLHLSFGEFSSKFAKAVKLAPWLGEPIIVTADPGSAPEPQADPGVDVIAWAHNETSTGVAVPVRRPEGSDD-ALVVI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 186 DATSAAGGVAADMSTIDAYYFSPQKNLSSDGGLWLAILSPAAIERSNRVTSSARWVPQMLDLSLAVTNSRADQTLNTPAL 265
Cdd:TIGR01366 161 DATSGAGGLPVDIAETDVYYFAPQKNFASDGGLWLAIMSPAALERIEAIAASGRWVPEFLSLPTAVDNSLKNQTYNTPAI 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 266 ATLVMLEAQCRWLLDQGGMAWAASRTASTSGILYRWAEDNPLTTPFVADPALRSPVVVTIDIDESVDAARLCARARDNGI 345
Cdd:TIGR01366 241 ATLALLAEQIDWMNGNGGLDWAVARTADSSSRLYSWAQERPYATPFVTDPGKRSQVVGTIDFVDDIDAATVAKILRANGI 320
|
330 340 350
....*....|....*....|....*....|....*....
gi 328758673 346 LDIEPYRKLGRNQIRIATFSSIEPSDVEALTACLDWLLE 384
Cdd:TIGR01366 321 VDTEPYRKLGRNQLRVAMFPAIDPDDVEALTECVDWVVE 359
|
|
| SerC |
COG1932 |
Phosphoserine aminotransferase [Coenzyme transport and metabolism, Amino acid transport and ... |
29-386 |
3.87e-117 |
|
Phosphoserine aminotransferase [Coenzyme transport and metabolism, Amino acid transport and metabolism]; Phosphoserine aminotransferase is part of the Pathway/BioSystem: Serine biosynthesis
Pssm-ID: 441535 Cd Length: 358 Bit Score: 344.36 E-value: 3.87e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 29 DPRFGCGPSRIRREVVASLSE-----PG---SVMGTSHRQPPVRHVVAAIREELTELYNLPTDYEVALGNGGATLFWDMA 100
Cdd:COG1932 3 VYNFSAGPAKLPEEVLEQAQAelldwNGsgmSVMEMSHRSKPFKAIVEEAEADLRELLGIPDGYEVLFLQGGATAQFAMV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 101 TVSLVE--KRAATGVYGEFTRKFSSALQRApflADPAVFQA--EPGKLALPKAVS-----DVDTYAWAHNETSTGVVAPv 171
Cdd:COG1932 83 PMNLLRggKKADYLVTGEWSKKAIKEAKKY---GEVNVVASseDDNFGYIPKPEEwqlspDADYVHYTSNETITGVEFH- 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 172 rRPNDIDDnSLVLVDATSAAGGVAADMSTIDAYYFSPQKNLSSdGGLWLAILSPAAIERSNRVTssarwvPQMLDLSlav 251
Cdd:COG1932 159 -ELPDVGD-VPLVADMSSDILSRPVDVSKFGLIYAGAQKNIGP-AGLTVVIVRPDLLGRAERAI------PSMLDYK--- 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 252 TNSRADQTLNTPALATLVMLEAQCRWLLDQGGMAWAASRTASTSGILYRWAEDNPLTTPFVaDPALRSPVVVTIDIDESV 331
Cdd:COG1932 227 THADNDSMYNTPPTFAIYLAGLVLKWLKEQGGLAAMEKRNAEKAALLYDWIDASDFYTNPV-DPEDRSRMNVTFDLADEE 305
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 328758673 332 DAARLCARARDNGILDIEPYRKLGrnQIRIATFSSIEPSDVEALTACLDWLLENR 386
Cdd:COG1932 306 LDAAFLAEAKAAGLVGLKGHRSVG--GMRASIYNAMPLEGVEALVDFMDEFERRH 358
|
|
| AGAT_like |
cd06451 |
Alanine-glyoxylate aminotransferase (AGAT) family. This family belongs to pyridoxal phosphate ... |
32-343 |
3.55e-24 |
|
Alanine-glyoxylate aminotransferase (AGAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to alanine-glyoxylate aminotransferase (AGAT), serine-glyoxylate aminotransferase (SGAT), and 3-hydroxykynurenine transaminase (HKT). AGAT is a homodimeric protein, which catalyses the transamination of glyoxylate to glycine, and SGAT converts serine and glyoxylate to hydroxypyruvate and glycine. HKT catalyzes the PLP-dependent transamination of 3-hydroxykynurenine, a potentially toxic metabolite of the kynurenine pathway.
Pssm-ID: 99744 [Multi-domain] Cd Length: 356 Bit Score: 101.98 E-value: 3.55e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 32 FGCGPSRIRREVVASLSEPgsVMGtsHRQPPVRHVVAAIREELTELYNlPTDYEVALGNGGATLFWDMATVSLVEK--RA 109
Cdd:cd06451 3 LIPGPSNVPPRVLKAMNRP--MLG--HRSPEFLALMDEILEGLRYVFQ-TENGLTFLLSGSGTGAMEAALSNLLEPgdKV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 110 ATGVYGEFTRKFSSALQRapFLADPAVFQAEPGKLALPKAVS------DVDTYAWAHNETSTGVVAPVRRPNDI--DDNS 181
Cdd:cd06451 78 LVGVNGVFGDRWADMAER--YGADVDVVEKPWGEAVSPEEIAealeqhDIKAVTLTHNETSTGVLNPLEGIGALakKHDA 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 182 LVLVDATSAAGGVAADMST--IDAYYFSPQKNLSSDGGLWLAILSPAAIERSNRVTSSARWvpqMLDLSL-AVTNSRADQ 258
Cdd:cd06451 156 LLIVDAVSSLGGEPFRMDEwgVDVAYTGSQKALGAPPGLGPIAFSERALERIKKKTKPKGF---YFDLLLlLKYWGEGYS 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 259 TLNTPALATLVMLEAQCRWLLDQGGMAWAASRTASTSGIlyrWAEDNPLTTPFVADPALRSPVVVTIDIDESVDAARLCA 338
Cdd:cd06451 233 YPHTPPVNLLYALREALDLILEEGLENRWARHRRLAKAL---REGLEALGLKLLAKPELRSPTVTAVLVPEGVDGDEVVR 309
|
....*
gi 328758673 339 RARDN 343
Cdd:cd06451 310 RLMKR 314
|
|
| Aminotran_5 |
pfam00266 |
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes ... |
157-340 |
4.23e-06 |
|
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.
Pssm-ID: 425567 [Multi-domain] Cd Length: 368 Bit Score: 48.40 E-value: 4.23e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 157 AWAHNETSTGVVAPVrrpNDI-----DDNSLVLVDATSAAGGVAADMST--IDAYYFSPQKNLSSDgGLWLAILSPAAIE 229
Cdd:pfam00266 144 AITHVSNVTGTIQPV---PEIgklahQYGALVLVDAAQAIGHRPIDVQKlgVDFLAFSGHKLYGPT-GIGVLYGRRDLLE 219
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 230 RSNRVTSSARWVPQmLDLSLAVTNSrADQTLN--TPALATLVMLEAQCRWlLDQGGMAWAASRTASTSGILYRWAEDNPL 307
Cdd:pfam00266 220 KMPPLLGGGGMIET-VSLQESTFAD-APWKFEagTPNIAGIIGLGAALEY-LSEIGLEAIEKHEHELAQYLYERLLSLPG 296
|
170 180 190
....*....|....*....|....*....|...
gi 328758673 308 TTpFVADPALRSPVVVTIDIDESVDAARLCARA 340
Cdd:pfam00266 297 IR-LYGPERRASIISFNFKGVHPHDVATLLDES 328
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK03080 |
PRK03080 |
phosphoserine transaminase; |
16-385 |
1.49e-173 |
|
phosphoserine transaminase;
Pssm-ID: 235103 Cd Length: 378 Bit Score: 488.54 E-value: 1.49e-173
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 16 MAQPMIPrDLLPSDPRFGCGPSRIRREV-VASLSepGSVMGTSHRQPPVRHVVAAIREELTELYNLPTDYEVALGNGGAT 94
Cdd:PRK03080 1 MTTLTIP-ALRPADPRFSSGPCKKRPGWqLEALA--DALLGRSHRQKPVKALLKRVIEGTRELLSLPEGYEVGIVPGSDT 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 95 LFWDMATVSLV-EKRAATGVYGEFTRKFSSALQRAPFLADPAVFQAEPGKLALPKAVSDVDTYAWAHNETSTGVVAPVRR 173
Cdd:PRK03080 78 GAWEMALWSLLgARRVDHLAWESFGSKWATDVVKQLKLEDPRVLEADYGSLPDLSAVDFDRDVVFTWNGTTTGVRVPVAR 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 174 PNDIDDNSLVLVDATSAAGGVAADMSTIDAYYFSPQKNLSSDGGLWLAILSPAAIERSNRVTsSARWVPQMLDLS---LA 250
Cdd:PRK03080 158 WIGADREGLTICDATSAAFALPLDWSKLDVYTFSWQKVLGGEGGHGMAILSPRAVERLESYT-PARPIPKFFRLTkggKA 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 251 VTNSRADQTLNTPALATLVMLEAQCRWLLDQGGMAWAASRTASTSGILYRWAEDNPLTTPFVADPALRSPVVVTIDIDE- 329
Cdd:PRK03080 237 IENSFKGQTINTPSMLTVEDYLDQLDWANSIGGLDALIARTAANASVLYDWAEKTPWATPLVADPATRSNTSVTLDFVDa 316
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 328758673 330 --SVDAARLCARARDNGILDIEPYRKlGRNQIRIATFSSIEPSDVEALTACLDWLLEN 385
Cdd:PRK03080 317 qaAVDAAAVAKLLRENGAVDIEPYRD-APNGLRIWCGPTVEPADVEALTPWLDWAFER 373
|
|
| serC_3 |
TIGR01366 |
phosphoserine aminotransferase, putative; This model represents a putative variant form of the ... |
27-384 |
1.37e-162 |
|
phosphoserine aminotransferase, putative; This model represents a putative variant form of the serine biosynthesis enzyme phosphoserine aminotransferase, as found in Mycobacterium tuberculosis and related high-GC Gram-positive bacteria. [Amino acid biosynthesis, Serine family]
Pssm-ID: 130433 Cd Length: 361 Bit Score: 460.17 E-value: 1.37e-162
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 27 PSDPRFGCGPSRIRREVVASLSEPG-SVMGTSHRQPPVRHVVAAIREELTELYNLPTDYEVALGNGGATLFWDMATVSLV 105
Cdd:TIGR01366 2 PRDGRFGSGPSKVRLEQLQALTTTAaSLFGTSHRQAPVKNLVGRVREGLAELFSLPDGYEVILGNGGATAFWDAATFGLI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 106 EKRAATGVYGEFTRKFSSALQRAPFLADPAVFQAEPGKLALPKAVSDVDTYAWAHNETSTGVVAPVRRPNDIDDnSLVLV 185
Cdd:TIGR01366 82 EKKSLHLSFGEFSSKFAKAVKLAPWLGEPIIVTADPGSAPEPQADPGVDVIAWAHNETSTGVAVPVRRPEGSDD-ALVVI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 186 DATSAAGGVAADMSTIDAYYFSPQKNLSSDGGLWLAILSPAAIERSNRVTSSARWVPQMLDLSLAVTNSRADQTLNTPAL 265
Cdd:TIGR01366 161 DATSGAGGLPVDIAETDVYYFAPQKNFASDGGLWLAIMSPAALERIEAIAASGRWVPEFLSLPTAVDNSLKNQTYNTPAI 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 266 ATLVMLEAQCRWLLDQGGMAWAASRTASTSGILYRWAEDNPLTTPFVADPALRSPVVVTIDIDESVDAARLCARARDNGI 345
Cdd:TIGR01366 241 ATLALLAEQIDWMNGNGGLDWAVARTADSSSRLYSWAQERPYATPFVTDPGKRSQVVGTIDFVDDIDAATVAKILRANGI 320
|
330 340 350
....*....|....*....|....*....|....*....
gi 328758673 346 LDIEPYRKLGRNQIRIATFSSIEPSDVEALTACLDWLLE 384
Cdd:TIGR01366 321 VDTEPYRKLGRNQLRVAMFPAIDPDDVEALTECVDWVVE 359
|
|
| SerC |
COG1932 |
Phosphoserine aminotransferase [Coenzyme transport and metabolism, Amino acid transport and ... |
29-386 |
3.87e-117 |
|
Phosphoserine aminotransferase [Coenzyme transport and metabolism, Amino acid transport and metabolism]; Phosphoserine aminotransferase is part of the Pathway/BioSystem: Serine biosynthesis
Pssm-ID: 441535 Cd Length: 358 Bit Score: 344.36 E-value: 3.87e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 29 DPRFGCGPSRIRREVVASLSE-----PG---SVMGTSHRQPPVRHVVAAIREELTELYNLPTDYEVALGNGGATLFWDMA 100
Cdd:COG1932 3 VYNFSAGPAKLPEEVLEQAQAelldwNGsgmSVMEMSHRSKPFKAIVEEAEADLRELLGIPDGYEVLFLQGGATAQFAMV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 101 TVSLVE--KRAATGVYGEFTRKFSSALQRApflADPAVFQA--EPGKLALPKAVS-----DVDTYAWAHNETSTGVVAPv 171
Cdd:COG1932 83 PMNLLRggKKADYLVTGEWSKKAIKEAKKY---GEVNVVASseDDNFGYIPKPEEwqlspDADYVHYTSNETITGVEFH- 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 172 rRPNDIDDnSLVLVDATSAAGGVAADMSTIDAYYFSPQKNLSSdGGLWLAILSPAAIERSNRVTssarwvPQMLDLSlav 251
Cdd:COG1932 159 -ELPDVGD-VPLVADMSSDILSRPVDVSKFGLIYAGAQKNIGP-AGLTVVIVRPDLLGRAERAI------PSMLDYK--- 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 252 TNSRADQTLNTPALATLVMLEAQCRWLLDQGGMAWAASRTASTSGILYRWAEDNPLTTPFVaDPALRSPVVVTIDIDESV 331
Cdd:COG1932 227 THADNDSMYNTPPTFAIYLAGLVLKWLKEQGGLAAMEKRNAEKAALLYDWIDASDFYTNPV-DPEDRSRMNVTFDLADEE 305
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 328758673 332 DAARLCARARDNGILDIEPYRKLGrnQIRIATFSSIEPSDVEALTACLDWLLENR 386
Cdd:COG1932 306 LDAAFLAEAKAAGLVGLKGHRSVG--GMRASIYNAMPLEGVEALVDFMDEFERRH 358
|
|
| PucG |
COG0075 |
Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism ... |
35-380 |
3.86e-32 |
|
Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG [Amino acid transport and metabolism, Nucleotide transport and metabolism]; Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG is part of the Pathway/BioSystem: Serine biosynthesis
Pssm-ID: 439845 [Multi-domain] Cd Length: 376 Bit Score: 124.43 E-value: 3.86e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 35 GPSRIRREVVASLSEPgsVMGtsHRQPPVRHVVAAIREELTELYNlpTDYEVALGNGGATLFWDMATVSLVEK--RAATG 112
Cdd:COG0075 7 GPTPVPPRVLRAMARP--MIG--HRDPEFVELMDEVRELLKKVFG--TENDVVILTGSGTGAMEAALANLVSPgdKVLVL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 113 VYGEFTRKFSSALQRAPflADPAVFQAEPGKLALPKAV-------SDVDTYAWAHNETSTGVVAPVR------RPNDIdd 179
Cdd:COG0075 81 VNGAFGERWAEIAERYG--AEVVVLEVPWGEAVDPEEVeealaadPDIKAVAVVHNETSTGVLNPLEeigalaKEHGA-- 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 180 nsLVLVDATSAAGGVAADMST--IDAYYFSPQKNLSSDGGLWLAILSPAAIERSNRVTsSARWvpqMLDLSLAVTNSRAD 257
Cdd:COG0075 157 --LLIVDAVSSLGGVPLDMDEwgIDVVVSGSQKCLMLPPGLAFVAVSERALEAIEARK-LPSY---YLDLKLWLKYWEKG 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 258 QTLNTPALATLVMLEAQCRWLLDQG-GMAWAasRTASTSGILYRWAEDNPLTtpFVADPALRSPVVVTIDIDESVDAARL 336
Cdd:COG0075 231 QTPYTPPVSLLYALREALDLILEEGlENRFA--RHRRLAEALRAGLEALGLE--LFAEEEYRSPTVTAVRVPEGVDAAAL 306
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 328758673 337 CARARDNgiLDIEPYRKLGRNQ---IRIATFSSIEPSDVEALTACLD 380
Cdd:COG0075 307 RKRLKER--YGIEIAGGLGPLKgkiFRIGHMGYVNPEDVLRTLAALE 351
|
|
| AGAT_like |
cd06451 |
Alanine-glyoxylate aminotransferase (AGAT) family. This family belongs to pyridoxal phosphate ... |
32-343 |
3.55e-24 |
|
Alanine-glyoxylate aminotransferase (AGAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to alanine-glyoxylate aminotransferase (AGAT), serine-glyoxylate aminotransferase (SGAT), and 3-hydroxykynurenine transaminase (HKT). AGAT is a homodimeric protein, which catalyses the transamination of glyoxylate to glycine, and SGAT converts serine and glyoxylate to hydroxypyruvate and glycine. HKT catalyzes the PLP-dependent transamination of 3-hydroxykynurenine, a potentially toxic metabolite of the kynurenine pathway.
Pssm-ID: 99744 [Multi-domain] Cd Length: 356 Bit Score: 101.98 E-value: 3.55e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 32 FGCGPSRIRREVVASLSEPgsVMGtsHRQPPVRHVVAAIREELTELYNlPTDYEVALGNGGATLFWDMATVSLVEK--RA 109
Cdd:cd06451 3 LIPGPSNVPPRVLKAMNRP--MLG--HRSPEFLALMDEILEGLRYVFQ-TENGLTFLLSGSGTGAMEAALSNLLEPgdKV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 110 ATGVYGEFTRKFSSALQRapFLADPAVFQAEPGKLALPKAVS------DVDTYAWAHNETSTGVVAPVRRPNDI--DDNS 181
Cdd:cd06451 78 LVGVNGVFGDRWADMAER--YGADVDVVEKPWGEAVSPEEIAealeqhDIKAVTLTHNETSTGVLNPLEGIGALakKHDA 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 182 LVLVDATSAAGGVAADMST--IDAYYFSPQKNLSSDGGLWLAILSPAAIERSNRVTSSARWvpqMLDLSL-AVTNSRADQ 258
Cdd:cd06451 156 LLIVDAVSSLGGEPFRMDEwgVDVAYTGSQKALGAPPGLGPIAFSERALERIKKKTKPKGF---YFDLLLlLKYWGEGYS 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 259 TLNTPALATLVMLEAQCRWLLDQGGMAWAASRTASTSGIlyrWAEDNPLTTPFVADPALRSPVVVTIDIDESVDAARLCA 338
Cdd:cd06451 233 YPHTPPVNLLYALREALDLILEEGLENRWARHRRLAKAL---REGLEALGLKLLAKPELRSPTVTAVLVPEGVDGDEVVR 309
|
....*
gi 328758673 339 RARDN 343
Cdd:cd06451 310 RLMKR 314
|
|
| PSAT_like |
cd00611 |
Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP) ... |
32-379 |
9.23e-16 |
|
Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT). PSAT is active as a dimer and catalyzes the conversion of phosphohydroxypyruvate to phosphoserine.
Pssm-ID: 99736 [Multi-domain] Cd Length: 355 Bit Score: 77.72 E-value: 9.23e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 32 FGCGPSRIRREVVASLSEP-------G-SVMGTSHRQPPVRHVVAAIREELTELYNLPTDYEVALGNGGATLFWDMATVS 103
Cdd:cd00611 3 FSAGPAALPEEVLEQAQKElldfnglGmSVMEMSHRSKDFEAIVNEAESDLRELLNIPDNYKVLFLQGGATGQFAAVPLN 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 104 LV--EKRAATGVYGEFTRKfssALQRAPFLAdPAVFQAEPGKLALPKAVSDVDT------YAWAH---NETSTGvvapVR 172
Cdd:cd00611 83 LLgdKGTADYVVTGAWSAK---AAKEAKRYG-GVVVIVAAKEEGKYTKIPDVETwdlapdAAYVHycsNETIHG----VE 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 173 RPNDIDDNSLVLV-DATSAAGGVAADMSTIDAYYFSPQKNLSSdGGLWLAILSPAAIERSNRVTssarwvPQMLDLSLAV 251
Cdd:cd00611 155 FDEVPDTGGVPLVaDMSSNILSRPIDVSKFGVIYAGAQKNLGP-AGVTVVIVRKDLLGKARKIT------PSMLNYKTHA 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 252 TNsraDQTLNTPALATLVMLEAQCRWLLDQGGMAWAASRTASTSGILYRWAEDNPLTTPFVADPALRSPVVVTIDI-DES 330
Cdd:cd00611 228 DN---NSLYNTPPTFAIYMMGLVLKWLKEQGGVEAMEKRNRQKAQLLYDTIDNSNGFYRGPVDKRARSRMNVPFRLgKEE 304
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 328758673 331 VDaARLCARARDNGILDIEPYRKLGrnQIRIATFSSIEPSDVEALTACL 379
Cdd:cd00611 305 LE-KEFLKEAEAAGMIGLKGHRSVG--GIRASIYNALSLEGVQALADFM 350
|
|
| PLN02409 |
PLN02409 |
serine--glyoxylate aminotransaminase |
22-342 |
1.37e-13 |
|
serine--glyoxylate aminotransaminase
Pssm-ID: 178031 [Multi-domain] Cd Length: 401 Bit Score: 71.71 E-value: 1.37e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 22 PRDLLpsdprFGCGPSRIRREVVASLSEPGSvmgtSHRQPPVRHVVAAIREELTELYNLPTDYEVAL---GNGGatlfWD 98
Cdd:PLN02409 8 GRNHL-----FVPGPVNIPERVLRAMNRPNE----DHRSPAFPALTKELLEDVKYIFKTKSGTPFIFpttGTGA----WE 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 99 MATVSLVE--KRAATGVYGEFTRKFSSALQRAPFlaDPAVFQAEPG----------KLAL-----PKAVSDVdtyawaHN 161
Cdd:PLN02409 75 SALTNTLSpgDKVVSFRIGQFSLLWIDQMQRLNF--DVDVVESPWGqgadldilksKLRQdtnhkIKAVCVV------HN 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 162 ETSTGV---VAPVRRPNDIDDN-SLVLVDATSAAGGVA--ADMSTIDAYYFSPQKNLSSDGGLWLAILSPAAIERSNRvt 235
Cdd:PLN02409 147 ETSTGVtndLAGVRKLLDCAQHpALLLVDGVSSIGALDfrMDEWGVDVALTGSQKALSLPTGLGIVCASPKALEASKT-- 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 236 ssARWVPQMLDLSLAV-TNSRADQTLNTPALATLVMLEAQCRwLLDQGGMAWAASRTASTSGILYRWAEDNPLtTPFVAD 314
Cdd:PLN02409 225 --AKSPRVFFDWADYLkFYKLGTYWPYTPSIQLLYGLRAALD-LIFEEGLENVIARHARLGEATRLAVEAWGL-KLCTKK 300
|
330 340
....*....|....*....|....*...
gi 328758673 315 PALRSPVVVTIDIDESVDAARLCARARD 342
Cdd:PLN02409 301 PEWRSDTVTAVVVPEGIDSAEIVKNAWK 328
|
|
| PRK12462 |
PRK12462 |
phosphoserine aminotransferase; Provisional |
41-377 |
1.29e-12 |
|
phosphoserine aminotransferase; Provisional
Pssm-ID: 183540 Cd Length: 364 Bit Score: 68.30 E-value: 1.29e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 41 REVVASLSEPG-SVMGTSHRQPPVRHVVAAIREELTELYNLPTDYEVALGNGGATLFWDMATVSLVEKRAATGVY---GE 116
Cdd:PRK12462 24 RQAVVELPETGlSVLGMSHRSSWFSSLLAQAEADLRDLLGIPDEYGVVFLQGGSSLQFSMIPMNFSRPGAAAPEYvttGY 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 117 FTRKfssALQRAPFLADPAVF--QAEPGKLALPkAVSDVDTYAWA------HNETSTGVVAPvrRPNDIDDNSLVlVDAT 188
Cdd:PRK12462 104 WSRK---AIGEASRVAAMRVVwdGAASGYRTLP-SLAELDWDARApfrhyvSNETVEGLQFP--DAAGLPDSPLI-ADMS 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 189 SAAGGVAADMSTIDAYYFSPQKNLSSdGGLWLAILSPAAIERSNRVtssarwVPQMLDLSlavTNSRADQTLNTPALATL 268
Cdd:PRK12462 177 SDFMSRPFDVEAYGMVYAHAQKNLGP-AGVTVAIIRRALLERVPDT------LPPMLDFR---THVEHRSNYNTPPVFAI 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 269 VMLEAQCRWLLDQ-GGMAWAASRTASTSGILYRWAEDNPLTTPFVADPALRSPVVVTIDIDESVDAARLCARARDNGILD 347
Cdd:PRK12462 247 YVMALVLRWIRDEiGGVHAMRDINARKAAMLYATLDALNEVIDCHAHRAARSTMNVAFRFRQPRLDTLFKEQSTEAGFCG 326
|
330 340 350
....*....|....*....|....*....|
gi 328758673 348 IEPYRKLGrnQIRIATFSSIEPSDVEALTA 377
Cdd:PRK12462 327 LSGHRSIG--GIRASLYNAVSEQAVSRLCA 354
|
|
| PRK05355 |
PRK05355 |
3-phosphoserine/phosphohydroxythreonine transaminase; |
52-346 |
1.92e-12 |
|
3-phosphoserine/phosphohydroxythreonine transaminase;
Pssm-ID: 235428 Cd Length: 360 Bit Score: 67.81 E-value: 1.92e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 52 SVMGTSHRQPPVRHVVAAIREELTELYNLPTDYEVALGNGGATLFWDMATVSLVE--KRAA---TGVYGEftrkfsSALQ 126
Cdd:PRK05355 35 SVMEISHRSKEFEAVAEEAEADLRELLNIPDNYKVLFLQGGASLQFAMVPMNLLGggKKADyvdTGSWSK------KAIK 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 127 RAPFLADPAVFQ--AEPGKLALPKAVSDV--DTYAWAH---NETSTGvvapVRRPNDIDDNSLVLVdatsaaggvaADM- 198
Cdd:PRK05355 109 EAKKYGEVNVAAssEDDGFTYIPPLDEWQlsDDAAYVHytsNETIDG----TEFHELPDTGDVPLV----------ADMs 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 199 STI----------DAYYFSPQKNLssdG--GLWLAILSPAAIERSNRVTSSarwvpqMLDLSLAVTNsraDQTLNTPA-- 264
Cdd:PRK05355 175 SDIlsrpidvskfGLIYAGAQKNI---GpaGLTIVIVREDLLGRALPSIPS------MLDYKTHADN---DSMYNTPPtf 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 265 ---LATLVMleaqcRWLLDQGGMAWAASRTASTSGILYRWAEDNPLTTPFVAdPALRSPVVVTIDI-DESVDAARLcARA 340
Cdd:PRK05355 243 aiyLAGLVF-----KWLKEQGGVAAMEKRNQEKAALLYDAIDSSDFYRNPVA-PEDRSRMNVPFTLaDEELDKKFL-AEA 315
|
....*.
gi 328758673 341 RDNGIL 346
Cdd:PRK05355 316 KAAGLV 321
|
|
| PLN02452 |
PLN02452 |
phosphoserine transaminase |
32-377 |
1.87e-11 |
|
phosphoserine transaminase
Pssm-ID: 178071 Cd Length: 365 Bit Score: 64.71 E-value: 1.87e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 32 FGCGPSRIRREVVASLS-------EPG-SVMGTSHRQPPVRHVVAAIREELTELYNLPTDYEVALGNGGATLFWDMATVS 103
Cdd:PLN02452 11 FSAGPATLPANVLAKAQaelynweGSGmSVMEMSHRGKEFLSIIQKAEADLRELLDIPDNYEVLFLQGGASTQFAAIPLN 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 104 LV--EKRAATGVYGEFTRKfssALQRAPFLADPAVfqAEPGKLALPKAVSDVDTY------AWAH---NETSTGV---VA 169
Cdd:PLN02452 91 LCkpGDKADFVVTGSWSKK---AAKEAKKYCKTNV--IASGKDEKYTKIPSVSEWeltpdaKFVHicaNETIHGVefkDY 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 170 PvrrpnDIDDNSLVlVDATSAAGGVAADMSTIDAYYFSPQKNLSSDGglwLAIlspaAIERSNRVTSSARWVPQMLDLSL 249
Cdd:PLN02452 166 P-----DVGNVPLV-ADMSSNFLSKPVDVSKYGVIYAGAQKNVGPSG---VTI----VIIRKDLIGNARPITPGMLDYKI 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 250 AVTNsraDQTLNTPALATLVMLEAQCRWLLDQGGMAWAASRTASTSGILYRW--AEDNPLTTPfvADPALRSPVVVTIDI 327
Cdd:PLN02452 233 HAEN---DSLYNTPPCFGIYMCGLVFEDLLAQGGLKAMEKRNIRKADLLYDAidESNGFYVCP--VEKSVRSLMNVPFTL 307
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 328758673 328 DESVDAARLCARARDNGILDIEPYRKLGrnQIRIATFSSIEPSDVEALTA 377
Cdd:PLN02452 308 GGSELEAEFVKEAAKAGMVQLKGHRSVG--GMRASIYNAMPLAGVEKLVA 355
|
|
| Aminotran_5 |
pfam00266 |
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes ... |
157-340 |
4.23e-06 |
|
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.
Pssm-ID: 425567 [Multi-domain] Cd Length: 368 Bit Score: 48.40 E-value: 4.23e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 157 AWAHNETSTGVVAPVrrpNDI-----DDNSLVLVDATSAAGGVAADMST--IDAYYFSPQKNLSSDgGLWLAILSPAAIE 229
Cdd:pfam00266 144 AITHVSNVTGTIQPV---PEIgklahQYGALVLVDAAQAIGHRPIDVQKlgVDFLAFSGHKLYGPT-GIGVLYGRRDLLE 219
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328758673 230 RSNRVTSSARWVPQmLDLSLAVTNSrADQTLN--TPALATLVMLEAQCRWlLDQGGMAWAASRTASTSGILYRWAEDNPL 307
Cdd:pfam00266 220 KMPPLLGGGGMIET-VSLQESTFAD-APWKFEagTPNIAGIIGLGAALEY-LSEIGLEAIEKHEHELAQYLYERLLSLPG 296
|
170 180 190
....*....|....*....|....*....|...
gi 328758673 308 TTpFVADPALRSPVVVTIDIDESVDAARLCARA 340
Cdd:pfam00266 297 IR-LYGPERRASIISFNFKGVHPHDVATLLDES 328
|
|
| |
