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Conserved domains on  [gi|330410462|gb|EGG89893|]
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hypothetical protein HMPREF1025_00001, partial [Lachnospiraceae bacterium 3_1_46FAA]

Protein Classification

transposase( domain architecture ID 706256)

transposase binds to the end of a transposon and catalyze the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism

Gene Ontology:  GO:0032196|GO:0004803

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Transposase_mut super family cl27632
Transposase, Mutator family;
14-116 6.65e-31

Transposase, Mutator family;


The actual alignment was detected with superfamily member COG3328:

Pssm-ID: 474953  Cd Length: 400  Bit Score: 112.60  E-value: 6.65e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 330410462  14 TEGKRNIIHQLLKEYDiQSAEDIQDALKDLLGGTIKEMMEAEMDDHLGYEKSQRSD--SGDYRNGYKRKRVNSRYGSMEI 91
Cdd:COG3328    1 KTLTKELLEELLSELL-EGDDLFDDLLRELLKELLEQALEAELDAHLGAEKYERTGgeRGNSRNGYRERTVKTRVGELEL 79
                         90       100
                 ....*....|....*....|....*
gi 330410462  92 EVPQDRKSTFEPQVVKKRQKDISDI 116
Cdd:COG3328   80 RVPRDRDGSFEPQLLPKYQRREQAL 104
 
Name Accession Description Interval E-value
IS285 COG3328
Transposase (or an inactivated derivative) [Mobilome: prophages, transposons];
14-116 6.65e-31

Transposase (or an inactivated derivative) [Mobilome: prophages, transposons];


Pssm-ID: 442557  Cd Length: 400  Bit Score: 112.60  E-value: 6.65e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 330410462  14 TEGKRNIIHQLLKEYDiQSAEDIQDALKDLLGGTIKEMMEAEMDDHLGYEKSQRSD--SGDYRNGYKRKRVNSRYGSMEI 91
Cdd:COG3328    1 KTLTKELLEELLSELL-EGDDLFDDLLRELLKELLEQALEAELDAHLGAEKYERTGgeRGNSRNGYRERTVKTRVGELEL 79
                         90       100
                 ....*....|....*....|....*
gi 330410462  92 EVPQDRKSTFEPQVVKKRQKDISDI 116
Cdd:COG3328   80 RVPRDRDGSFEPQLLPKYQRREQAL 104
transpos_IS256 NF033543
IS256 family transposase; Members of this family belong to the branch of the IS256-like family ...
23-115 1.50e-26

IS256 family transposase; Members of this family belong to the branch of the IS256-like family of transposases that includes the founding member. It excludes the IS1249 group.


Pssm-ID: 468074 [Multi-domain]  Cd Length: 406  Bit Score: 101.14  E-value: 1.50e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 330410462  23 QLLKEYDIQSAEDIQDALKDLLGGTIKEMMEAEMDDHLGYEKSQRSDSGDYRNGYKRKRVNSRYGSMEIEVPQDRKSTFE 102
Cdd:NF033543  12 EALLGLKALEDLTDDELLRELLKALLEQLLEAELTAHLGAEKYERTGRGNVRNGYYPRTVLTRGGPVELRVPRDRDGSFE 91
                         90
                 ....*....|...
gi 330410462 103 PQVVKKRQKDISD 115
Cdd:NF033543  92 PQLILKRYRRSEK 104
Transposase_mut pfam00872
Transposase, Mutator family;
23-111 1.73e-19

Transposase, Mutator family;


Pssm-ID: 307151  Cd Length: 380  Bit Score: 81.66  E-value: 1.73e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 330410462   23 QLLKEYDIQSAEDIQDALKDLLGGTIKEMMEAEMDDHLGYEKSQRSDSG-DYRNGYKRKRVNSRYGSMEIEVPQDRKSTF 101
Cdd:pfam00872   9 DSEALQAIIELQGKDDLLRTLLKTVMNALLEAELTEHLGAARYERTEERsNQRNGSYSRTFITRAGTLELRIPRDRNGSF 88
                          90
                  ....*....|
gi 330410462  102 EPQVVKKRQK 111
Cdd:pfam00872  89 SPALLERYQR 98
 
Name Accession Description Interval E-value
IS285 COG3328
Transposase (or an inactivated derivative) [Mobilome: prophages, transposons];
14-116 6.65e-31

Transposase (or an inactivated derivative) [Mobilome: prophages, transposons];


Pssm-ID: 442557  Cd Length: 400  Bit Score: 112.60  E-value: 6.65e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 330410462  14 TEGKRNIIHQLLKEYDiQSAEDIQDALKDLLGGTIKEMMEAEMDDHLGYEKSQRSD--SGDYRNGYKRKRVNSRYGSMEI 91
Cdd:COG3328    1 KTLTKELLEELLSELL-EGDDLFDDLLRELLKELLEQALEAELDAHLGAEKYERTGgeRGNSRNGYRERTVKTRVGELEL 79
                         90       100
                 ....*....|....*....|....*
gi 330410462  92 EVPQDRKSTFEPQVVKKRQKDISDI 116
Cdd:COG3328   80 RVPRDRDGSFEPQLLPKYQRREQAL 104
transpos_IS256 NF033543
IS256 family transposase; Members of this family belong to the branch of the IS256-like family ...
23-115 1.50e-26

IS256 family transposase; Members of this family belong to the branch of the IS256-like family of transposases that includes the founding member. It excludes the IS1249 group.


Pssm-ID: 468074 [Multi-domain]  Cd Length: 406  Bit Score: 101.14  E-value: 1.50e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 330410462  23 QLLKEYDIQSAEDIQDALKDLLGGTIKEMMEAEMDDHLGYEKSQRSDSGDYRNGYKRKRVNSRYGSMEIEVPQDRKSTFE 102
Cdd:NF033543  12 EALLGLKALEDLTDDELLRELLKALLEQLLEAELTAHLGAEKYERTGRGNVRNGYYPRTVLTRGGPVELRVPRDRDGSFE 91
                         90
                 ....*....|...
gi 330410462 103 PQVVKKRQKDISD 115
Cdd:NF033543  92 PQLILKRYRRSEK 104
Transposase_mut pfam00872
Transposase, Mutator family;
23-111 1.73e-19

Transposase, Mutator family;


Pssm-ID: 307151  Cd Length: 380  Bit Score: 81.66  E-value: 1.73e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 330410462   23 QLLKEYDIQSAEDIQDALKDLLGGTIKEMMEAEMDDHLGYEKSQRSDSG-DYRNGYKRKRVNSRYGSMEIEVPQDRKSTF 101
Cdd:pfam00872   9 DSEALQAIIELQGKDDLLRTLLKTVMNALLEAELTEHLGAARYERTEERsNQRNGSYSRTFITRAGTLELRIPRDRNGSF 88
                          90
                  ....*....|
gi 330410462  102 EPQVVKKRQK 111
Cdd:pfam00872  89 SPALLERYQR 98
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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