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Conserved domains on  [gi|336009587|gb|EGN39579|]
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hypothetical protein HMPREF0994_03506 [Lachnospiraceae bacterium 3_1_57FAA_CT1]

Protein Classification

sialate O-acetylesterase( domain architecture ID 10508108)

sialate O-acetylesterase catalyzes the removal of O-acetyl ester groups from position 9 of free and/or glycosidically-bound N-acetyl- or N-glycoloylneuraminic acid such as 9-O-acetyl-N-acetylneuraminate

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
SASA pfam03629
Carbohydrate esterase, sialic acid-specific acetylesterase; The catalytic triad of this ...
120-345 1.13e-67

Carbohydrate esterase, sialic acid-specific acetylesterase; The catalytic triad of this esterase enzyme comprises residues Ser127, His403 and Asp391 in UniProtKB:P70665.


:

Pssm-ID: 427409  Cd Length: 227  Bit Score: 216.30  E-value: 1.13e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 336009587  120 VGNLFLIAGQSNSAGYGK---------DYCTDPPHlcVHLFRNRNQWDLASHPMNESTAAGSlpneemgIPGVSPYLSFG 190
Cdd:pfam03629   1 PKDIFLLAGQSNMAGRGGvenwdgvvpPECQPPPR--ILRLNADLEWEEAREPLHADIDAKK-------TCGVGPGMAFA 71
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 336009587  191 KKYYEL-TGMPVGLIQTAQGGSSIERWNPKdGDLYGNMMNKIRET--KGRYAGVLWYQGCEDT-RPEQAEAYGEHFRELA 266
Cdd:pfam03629  72 NALLRApPGGVIGLVPCAVGGTSIEEWARG-GLLYQEMVRRAKAAlkGGEIKGILWYQGESDTsDEEDAAAYKEKLEKLI 150
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 336009587  267 EALRAALGY-EIPFFTMQLNRFiNGPFdeaWGMVREAQrrAALSIPAVFVLPTTNLSL-SDSVHNSAQANVALGIRLARQ 344
Cdd:pfam03629 151 TDLRDDLGLpDLPIIQVQLASG-EGPY---EEVVREAQ--LGIKLPNVTVVDAKGLPLkDDNLHLTTESQVLLGKRLAEA 224

                  .
gi 336009587  345 C 345
Cdd:pfam03629 225 M 225
 
Name Accession Description Interval E-value
SASA pfam03629
Carbohydrate esterase, sialic acid-specific acetylesterase; The catalytic triad of this ...
120-345 1.13e-67

Carbohydrate esterase, sialic acid-specific acetylesterase; The catalytic triad of this esterase enzyme comprises residues Ser127, His403 and Asp391 in UniProtKB:P70665.


Pssm-ID: 427409  Cd Length: 227  Bit Score: 216.30  E-value: 1.13e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 336009587  120 VGNLFLIAGQSNSAGYGK---------DYCTDPPHlcVHLFRNRNQWDLASHPMNESTAAGSlpneemgIPGVSPYLSFG 190
Cdd:pfam03629   1 PKDIFLLAGQSNMAGRGGvenwdgvvpPECQPPPR--ILRLNADLEWEEAREPLHADIDAKK-------TCGVGPGMAFA 71
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 336009587  191 KKYYEL-TGMPVGLIQTAQGGSSIERWNPKdGDLYGNMMNKIRET--KGRYAGVLWYQGCEDT-RPEQAEAYGEHFRELA 266
Cdd:pfam03629  72 NALLRApPGGVIGLVPCAVGGTSIEEWARG-GLLYQEMVRRAKAAlkGGEIKGILWYQGESDTsDEEDAAAYKEKLEKLI 150
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 336009587  267 EALRAALGY-EIPFFTMQLNRFiNGPFdeaWGMVREAQrrAALSIPAVFVLPTTNLSL-SDSVHNSAQANVALGIRLARQ 344
Cdd:pfam03629 151 TDLRDDLGLpDLPIIQVQLASG-EGPY---EEVVREAQ--LGIKLPNVTVVDAKGLPLkDDNLHLTTESQVLLGKRLAEA 224

                  .
gi 336009587  345 C 345
Cdd:pfam03629 225 M 225
 
Name Accession Description Interval E-value
SASA pfam03629
Carbohydrate esterase, sialic acid-specific acetylesterase; The catalytic triad of this ...
120-345 1.13e-67

Carbohydrate esterase, sialic acid-specific acetylesterase; The catalytic triad of this esterase enzyme comprises residues Ser127, His403 and Asp391 in UniProtKB:P70665.


Pssm-ID: 427409  Cd Length: 227  Bit Score: 216.30  E-value: 1.13e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 336009587  120 VGNLFLIAGQSNSAGYGK---------DYCTDPPHlcVHLFRNRNQWDLASHPMNESTAAGSlpneemgIPGVSPYLSFG 190
Cdd:pfam03629   1 PKDIFLLAGQSNMAGRGGvenwdgvvpPECQPPPR--ILRLNADLEWEEAREPLHADIDAKK-------TCGVGPGMAFA 71
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 336009587  191 KKYYEL-TGMPVGLIQTAQGGSSIERWNPKdGDLYGNMMNKIRET--KGRYAGVLWYQGCEDT-RPEQAEAYGEHFRELA 266
Cdd:pfam03629  72 NALLRApPGGVIGLVPCAVGGTSIEEWARG-GLLYQEMVRRAKAAlkGGEIKGILWYQGESDTsDEEDAAAYKEKLEKLI 150
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 336009587  267 EALRAALGY-EIPFFTMQLNRFiNGPFdeaWGMVREAQrrAALSIPAVFVLPTTNLSL-SDSVHNSAQANVALGIRLARQ 344
Cdd:pfam03629 151 TDLRDDLGLpDLPIIQVQLASG-EGPY---EEVVREAQ--LGIKLPNVTVVDAKGLPLkDDNLHLTTESQVLLGKRLAEA 224

                  .
gi 336009587  345 C 345
Cdd:pfam03629 225 M 225
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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