|
Name |
Accession |
Description |
Interval |
E-value |
| SpoU |
COG0566 |
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA ... |
11-248 |
4.41e-69 |
|
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA G18 (ribose-2'-O)-methylase SpoU is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440332 [Multi-domain] Cd Length: 265 Bit Score: 213.90 E-value: 4.41e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384468738 11 KEQTRKARAAETVWL-FGLHAVRDALLNpRREKLRLIVTPNAELRLADAIAAA---GITPDVQDPRRFDApLDPQSVHQG 86
Cdd:COG0566 14 KLRDKKYREEEGLFLaEGRHAVEEALKA-GREIEELLVTEGALDRLAELLALAkaaGIPVYEVSREVLDK-LSGTETHQG 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384468738 87 AALEAKPLDWGHLGDVaLGDGTRPPRLVLLDRVTDPHNVGAILRSAEVFGAQAVIGTLHHSAPETGALAKTASGALERQP 166
Cdd:COG0566 92 VLAVVRPPEYADLEDL-LAEAGEPPLLLVLDGVQDPGNLGAILRSAAAFGVDGVILPKRRADPYNPKVVRASAGALFHVP 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384468738 167 YLRERNLSDTIQALQEMGYLVLGLDGDAEDTV-EAALDGlrdrAVALVLGAEGPGLRQKTRETVDRLVRIDFAGGFGSLN 245
Cdd:COG0566 171 VARVTNLADALEELKEAGFWVVGTDLDGEASLyEVDLPG----PVALVLGNEGKGLSRLVLEACDELVRIPMAGGVESLN 246
|
...
gi 384468738 246 VSN 248
Cdd:COG0566 247 VAV 249
|
|
| SpoU-like_RlmB |
cd18103 |
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the ... |
113-248 |
1.51e-53 |
|
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the methylation of guanosine 2251, a modification conserved in the peptidyltransferase domain of 23S rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349976 Cd Length: 143 Bit Score: 169.87 E-value: 1.51e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384468738 113 LVLLDRVTDPHNVGAILRSAEVFGAQAVIGTLHHSAPETGALAKTASGALERQPYLRERNLSDTIQALQEMGYLVLGLDG 192
Cdd:cd18103 2 LLILDGITDPHNLGAIIRSAEAFGVDGVIIPKRRSAPLTPTVAKASAGALEHLPIARVTNLARALEELKEAGFWIYGADG 81
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 384468738 193 DAEDTV-EAALDGlrdrAVALVLGAEGPGLRQKTRETVDRLVRIDFAGGFGSLNVSN 248
Cdd:cd18103 82 EAEKSLyDVDLTG----PLALVLGSEGKGLRRLVLKNCDFLVKIPMAGKVDSLNVSV 134
|
|
| rRNA_methyl_3 |
TIGR00186 |
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases ... |
25-247 |
1.65e-52 |
|
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129290 [Multi-domain] Cd Length: 237 Bit Score: 170.60 E-value: 1.65e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384468738 25 LFGLHAVRDALLNPRREKLRLIVTPNAELRLADAIAAAGITPDVQDPRRFDAPLDpQSVHQGAALEAKP---LDWGHLGD 101
Cdd:TIGR00186 4 LYGKNAVLEALLNQQRVFILKGLESKRLKKLIQLAKKQGINIQLVDRQKLDQLTK-GGNHQGIAAKVKPilyKDLNDLYK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384468738 102 VALGDGTrpPRLVLLDRVTDPHNVGAILRSAEVFGAQAVIGTLHHSAPETGALAKTASGALERQPYLRERNLSDTIQALQ 181
Cdd:TIGR00186 83 TAKSKKQ--PFLLILDEITDPHNLGAILRTAEAFGVDGVILPKRRSAPLNSTVVKTSSGAVEYVPLARVTNLSRTITKLK 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 384468738 182 EMGYLVLGLDGDAEDTVEAALDGLRdraVALVLGAEGPGLRQKTRETVDRLVRIDFAGGFGSLNVS 247
Cdd:TIGR00186 161 ESGFWTVGTDLDAQDTLYQVKLTKP---LALVVGNEGEGVSRLIKENCDFLIKIPMAGKVDSLNVS 223
|
|
| PRK11181 |
PRK11181 |
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB; |
24-247 |
9.11e-40 |
|
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB;
Pssm-ID: 183021 [Multi-domain] Cd Length: 244 Bit Score: 137.79 E-value: 9.11e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384468738 24 WLFGLHAVRdALLNprREKLRLI------------VTPnaelrLADAIAAAGITpdVQDPRRfdAPLDPQS---VHQGAA 88
Cdd:PRK11181 4 IIYGIHAVQ-ALLE--RAPERFIevfvlkgredkrLLP-----LINELEAQGIV--IQLANR--QTLDEKAegaVHQGII 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384468738 89 LEAKP---LDWGHLGDvaLGDGTRPPRLVLLDRVTDPHNVGAILRSAEVFGAQAVIGTLHHSAPETGALAKTASGALERQ 165
Cdd:PRK11181 72 ARVKPgrqLQENDLPD--LLASLEQPFLLILDGVTDPHNLGACLRSADAAGVHAVIVPKDRSAQLNATAKKVACGAAETV 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384468738 166 PYLRERNLSDTIQALQEMGYLVLGLDGDAEDTV-EAALDGlrdrAVALVLGAEGPGLRQKTRETVDRLVRIDFAGGFGSL 244
Cdd:PRK11181 150 PLIRVTNLARTMRMLQEKNIWIVGTAGEADHTLyQSKLTG----PLALVMGAEGEGMRRLTREHCDELISIPMAGSVSSL 225
|
...
gi 384468738 245 NVS 247
Cdd:PRK11181 226 NVS 228
|
|
| SpoU_methylase |
pfam00588 |
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet. |
111-248 |
4.66e-35 |
|
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet.
Pssm-ID: 425768 Cd Length: 142 Bit Score: 122.64 E-value: 4.66e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384468738 111 PRLVLLDRVTDPHNVGAILRSAEVFGAQAVIGTLHHSA-PETGALAKTASGALERQPYLRERNLSDTIQALQEMGYLVLG 189
Cdd:pfam00588 1 PLVVVLDNIQDPGNLGAIIRTAAAFGADGLILVEPRSAdPYNPKAIRASAGALFHLPLVVVDNLEEALKDLKEAGYAVVA 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 384468738 190 LDGDAEDTVEAALDGlrdrAVALVLGAEGPGLRQKTRETVDRLVRIDFAGGFGSLNVSN 248
Cdd:pfam00588 81 TSLGGKSLYEIDFPK----KVALVFGNEGTGLSNEVLELCDRLVRIPMSGDVESLNVAV 135
|
|
| SpoU_sub_bind |
smart00967 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
25-93 |
9.08e-07 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 214943 [Multi-domain] Cd Length: 70 Bit Score: 45.22 E-value: 9.08e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 384468738 25 LFGLHAVRDALLNPRREKlRLIVTPNAELRLADAIAAA---GITPDVQDPRRFDAPLDPQsVHQGAALEAKP 93
Cdd:smart00967 1 IEGRHAVEEALKSGRRIK-ELYLTEGRAERLKELLKLAkerGIKVIEVSKKELDKLSGTA-NHQGVVAVVKP 70
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| SpoU |
COG0566 |
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA ... |
11-248 |
4.41e-69 |
|
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA G18 (ribose-2'-O)-methylase SpoU is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440332 [Multi-domain] Cd Length: 265 Bit Score: 213.90 E-value: 4.41e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384468738 11 KEQTRKARAAETVWL-FGLHAVRDALLNpRREKLRLIVTPNAELRLADAIAAA---GITPDVQDPRRFDApLDPQSVHQG 86
Cdd:COG0566 14 KLRDKKYREEEGLFLaEGRHAVEEALKA-GREIEELLVTEGALDRLAELLALAkaaGIPVYEVSREVLDK-LSGTETHQG 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384468738 87 AALEAKPLDWGHLGDVaLGDGTRPPRLVLLDRVTDPHNVGAILRSAEVFGAQAVIGTLHHSAPETGALAKTASGALERQP 166
Cdd:COG0566 92 VLAVVRPPEYADLEDL-LAEAGEPPLLLVLDGVQDPGNLGAILRSAAAFGVDGVILPKRRADPYNPKVVRASAGALFHVP 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384468738 167 YLRERNLSDTIQALQEMGYLVLGLDGDAEDTV-EAALDGlrdrAVALVLGAEGPGLRQKTRETVDRLVRIDFAGGFGSLN 245
Cdd:COG0566 171 VARVTNLADALEELKEAGFWVVGTDLDGEASLyEVDLPG----PVALVLGNEGKGLSRLVLEACDELVRIPMAGGVESLN 246
|
...
gi 384468738 246 VSN 248
Cdd:COG0566 247 VAV 249
|
|
| SpoU-like_RlmB |
cd18103 |
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the ... |
113-248 |
1.51e-53 |
|
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the methylation of guanosine 2251, a modification conserved in the peptidyltransferase domain of 23S rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349976 Cd Length: 143 Bit Score: 169.87 E-value: 1.51e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384468738 113 LVLLDRVTDPHNVGAILRSAEVFGAQAVIGTLHHSAPETGALAKTASGALERQPYLRERNLSDTIQALQEMGYLVLGLDG 192
Cdd:cd18103 2 LLILDGITDPHNLGAIIRSAEAFGVDGVIIPKRRSAPLTPTVAKASAGALEHLPIARVTNLARALEELKEAGFWIYGADG 81
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 384468738 193 DAEDTV-EAALDGlrdrAVALVLGAEGPGLRQKTRETVDRLVRIDFAGGFGSLNVSN 248
Cdd:cd18103 82 EAEKSLyDVDLTG----PLALVLGSEGKGLRRLVLKNCDFLVKIPMAGKVDSLNVSV 134
|
|
| rRNA_methyl_3 |
TIGR00186 |
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases ... |
25-247 |
1.65e-52 |
|
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129290 [Multi-domain] Cd Length: 237 Bit Score: 170.60 E-value: 1.65e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384468738 25 LFGLHAVRDALLNPRREKLRLIVTPNAELRLADAIAAAGITPDVQDPRRFDAPLDpQSVHQGAALEAKP---LDWGHLGD 101
Cdd:TIGR00186 4 LYGKNAVLEALLNQQRVFILKGLESKRLKKLIQLAKKQGINIQLVDRQKLDQLTK-GGNHQGIAAKVKPilyKDLNDLYK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384468738 102 VALGDGTrpPRLVLLDRVTDPHNVGAILRSAEVFGAQAVIGTLHHSAPETGALAKTASGALERQPYLRERNLSDTIQALQ 181
Cdd:TIGR00186 83 TAKSKKQ--PFLLILDEITDPHNLGAILRTAEAFGVDGVILPKRRSAPLNSTVVKTSSGAVEYVPLARVTNLSRTITKLK 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 384468738 182 EMGYLVLGLDGDAEDTVEAALDGLRdraVALVLGAEGPGLRQKTRETVDRLVRIDFAGGFGSLNVS 247
Cdd:TIGR00186 161 ESGFWTVGTDLDAQDTLYQVKLTKP---LALVVGNEGEGVSRLIKENCDFLIKIPMAGKVDSLNVS 223
|
|
| PRK11181 |
PRK11181 |
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB; |
24-247 |
9.11e-40 |
|
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB;
Pssm-ID: 183021 [Multi-domain] Cd Length: 244 Bit Score: 137.79 E-value: 9.11e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384468738 24 WLFGLHAVRdALLNprREKLRLI------------VTPnaelrLADAIAAAGITpdVQDPRRfdAPLDPQS---VHQGAA 88
Cdd:PRK11181 4 IIYGIHAVQ-ALLE--RAPERFIevfvlkgredkrLLP-----LINELEAQGIV--IQLANR--QTLDEKAegaVHQGII 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384468738 89 LEAKP---LDWGHLGDvaLGDGTRPPRLVLLDRVTDPHNVGAILRSAEVFGAQAVIGTLHHSAPETGALAKTASGALERQ 165
Cdd:PRK11181 72 ARVKPgrqLQENDLPD--LLASLEQPFLLILDGVTDPHNLGACLRSADAAGVHAVIVPKDRSAQLNATAKKVACGAAETV 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384468738 166 PYLRERNLSDTIQALQEMGYLVLGLDGDAEDTV-EAALDGlrdrAVALVLGAEGPGLRQKTRETVDRLVRIDFAGGFGSL 244
Cdd:PRK11181 150 PLIRVTNLARTMRMLQEKNIWIVGTAGEADHTLyQSKLTG----PLALVMGAEGEGMRRLTREHCDELISIPMAGSVSSL 225
|
...
gi 384468738 245 NVS 247
Cdd:PRK11181 226 NVS 228
|
|
| SpoU_methylase |
pfam00588 |
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet. |
111-248 |
4.66e-35 |
|
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet.
Pssm-ID: 425768 Cd Length: 142 Bit Score: 122.64 E-value: 4.66e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384468738 111 PRLVLLDRVTDPHNVGAILRSAEVFGAQAVIGTLHHSA-PETGALAKTASGALERQPYLRERNLSDTIQALQEMGYLVLG 189
Cdd:pfam00588 1 PLVVVLDNIQDPGNLGAIIRTAAAFGADGLILVEPRSAdPYNPKAIRASAGALFHLPLVVVDNLEEALKDLKEAGYAVVA 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 384468738 190 LDGDAEDTVEAALDGlrdrAVALVLGAEGPGLRQKTRETVDRLVRIDFAGGFGSLNVSN 248
Cdd:pfam00588 81 TSLGGKSLYEIDFPK----KVALVFGNEGTGLSNEVLELCDRLVRIPMSGDVESLNVAV 135
|
|
| SpoU-like_MRM1 |
cd18105 |
SAM-dependent rRNA methylase related to MRM1; MRM1 catalyzes the methylation of 2'-O-ribose ... |
114-247 |
2.40e-32 |
|
SAM-dependent rRNA methylase related to MRM1; MRM1 catalyzes the methylation of 2'-O-ribose residues G1145 to GmG residue of the mitochondrial 16S rRNA. MRM1 is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349978 Cd Length: 158 Bit Score: 116.08 E-value: 2.40e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384468738 114 VLLDRVTDPHNVGAILRSAEVFGAQAVIGTLHHSAPETGALAKTASGALERQPYLRERNLSDTIQALQEMGYLVLGLDGD 193
Cdd:cd18105 3 LLLDEITDPQNLGAILRSAYFLGVDGVVVSSKNSAPLSPVVSKASAGALELMPIYSVDNLASFLKSSKENGWKVVGTSAP 82
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 384468738 194 AEDT-------VEAALDGLRDRAVALVLGAEGPGLRQKTRETVDRLVRIDFAGGFG-----SLNVS 247
Cdd:cd18105 83 PSASsdkktipANELSELLLEKPTILVLGNEGRGLRTNIKNLCDYLVSIPGGRSAEnpgvdSLNVS 148
|
|
| SpoU-like_rRNA-MTase |
cd18095 |
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
112-248 |
6.08e-31 |
|
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349968 Cd Length: 143 Bit Score: 111.75 E-value: 6.08e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384468738 112 RLVLLDRVTDPHNVGAILRSAEVFGAQAVIgTLHHSA-PETGALAKTASGALERQPYLRERNLSDTIQALQEMGYLVLGL 190
Cdd:cd18095 1 LVLVLDGVQDPGNLGTIIRTAAAFGVDGVI-LSKGTVdPYNPKVVRASMGALFRLPIIRVDDLEELLEELKEAGYKVVAA 79
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 384468738 191 DGDAEDTVEAALDglrDRAVALVLGAEGPGLRQKTRETVDRLVRIDFAGGFGSLNVSN 248
Cdd:cd18095 80 DLDGGSSLYDLDL---PKPVALVLGNEGNGLSDELLELCDKRVTIPMSGGVESLNVAV 134
|
|
| SpoU-like |
cd18097 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
114-248 |
4.29e-22 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349970 Cd Length: 144 Bit Score: 88.78 E-value: 4.29e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384468738 114 VLLDRVTDPHNVGAILRSAEVFGAQAVIGTLHHSAPETGALAKTASGALERQPYLRERNLSDTIQALQEMGYLVLGLDG- 192
Cdd:cd18097 3 VVLDNLRSAHNVGSIFRTADAAGVEKIYLCGYTPTPPHPKVAKTALGAEESVPWEHFEDTLEAVRALKARGYTIIALETt 82
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 384468738 193 -DAEDTVEAALDglrdRAVALVLGAEGPGLRQKTRETVDRLVRIDFAGGFGSLNVSN 248
Cdd:cd18097 83 eNSVPLHEARLP----RPLALVLGNEVRGVSPEVLALCDAVVEIPMFGRKNSLNVAV 135
|
|
| SpoU-like_family |
cd18082 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
114-248 |
5.55e-22 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349955 Cd Length: 145 Bit Score: 88.44 E-value: 5.55e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384468738 114 VLLDRVTDPHNVGAILRSAEVFGAQAVIGTLHHSAPETGALAKTASGALERQPYLRERNLSDTIQALQEMGYLVLGLDGD 193
Cdd:cd18082 2 LVLDNIRSPGNIGSIFRTADAFGVEKIYLVGPTADIFDPKAKRTSRGTHFSVPYERVDNFEEYLKSLKEEGYPLIGLELT 81
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 384468738 194 AEDTVEAALDGLRDRAVALVLGAEGPGLRQKTRETVDRLVRIDFAGGFGSLNVSN 248
Cdd:cd18082 82 DGSIPLSEFKFKKPKKIALIFGNERSGLSPELLALCDYTVHIPMSGKNSSLNVSV 136
|
|
| SpoU-like_TrmH |
cd18092 |
SAM-dependent tRNA methylase related to TrmH; TrmH catalyzes the transfer of the methyl group ... |
109-247 |
5.83e-17 |
|
SAM-dependent tRNA methylase related to TrmH; TrmH catalyzes the transfer of the methyl group from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of the ribose of the universally conserved guanosine 18 (G18) position in tRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349965 Cd Length: 162 Bit Score: 75.58 E-value: 5.83e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384468738 109 RPPRL-VLLDRVTDPHNVGAILRSAEVFGaqavIGTLH--HSAPETGALAKTASGAlerQPYL---RERNLSDTIQALQE 182
Cdd:cd18092 13 RTRDLtVVLENVHDPHNASAVLRTCDAFG----VQDVHviEPKNKFKKNRGVAMGA---DKWLdvhRHDSTEECLAALKE 85
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 384468738 183 MGYLVLG--LDGDAEDTVEAALdglrDRAVALVLGAEGPGLRQKTRETVDRLVRIDFAGGFGSLNVS 247
Cdd:cd18092 86 QGYRIVAtsLSPDAVPLDELDY----TRPTALVFGNEKDGVSEEALAAADERVYIPMYGFVESLNVS 148
|
|
| PRK10864 |
PRK10864 |
putative methyltransferase; Provisional |
116-247 |
6.29e-14 |
|
putative methyltransferase; Provisional
Pssm-ID: 236779 [Multi-domain] Cd Length: 346 Bit Score: 70.19 E-value: 6.29e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384468738 116 LDRVTDPHNVGAILRSAEVFGAQAVIGTlHHSAPETGALAKTASGALERQPYLRERNLSDTIQALQEMGYLVLGLDGDAE 195
Cdd:PRK10864 203 LEDVGNPHNLGGIMRSCAHFGVKGVVVQ-DAALLESGAAIRTAEGGAEHVQPITGDSFVDVLDDFRQAGYTIVTTSSHKG 281
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 384468738 196 DTVEAAldGLRDRAVaLVLGAEGPGLRQKTRETVDRLVRIDFAGGFGSLNVS 247
Cdd:PRK10864 282 TPLFKA--SLPAKMV-LVLGQEYDGLSDAARQQGDLSVSIDGTGNVESLNVS 330
|
|
| SpoU-like_RNA-MTase |
cd18109 |
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
112-247 |
8.74e-12 |
|
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349982 Cd Length: 141 Bit Score: 61.02 E-value: 8.74e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384468738 112 RLVLLDRVTDPHNVGAILRSAEVFGAQAVI---GTLHHSAPetgalaKT--AS-GALERQPyLRERNLSDTIQALQEmGY 185
Cdd:cd18109 1 LTLALDGIQDPGNLGTIIRTADWFGIRQIIcspDTVDPYNP------KVvqASmGSIFRVQ-IHYTDLPALLAELKK-AF 72
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 384468738 186 LVLGLDGDAEDTVEAAldgLRDRAVaLVLGAEGPGLRQKTRETVDRLVRIDFAGGFG-SLNVS 247
Cdd:cd18109 73 PVYGADLDGENLYEFT---LPEKGI-LVMGNEGHGISPEVLKLLTHRLTIPRYGKGAeSLNVA 131
|
|
| SpoU-like_AviRb |
cd18107 |
SAM-dependent rRNA methylase related to AviRb; AviRb from Streptomyces viridochromogenes ... |
114-248 |
3.08e-11 |
|
SAM-dependent rRNA methylase related to AviRb; AviRb from Streptomyces viridochromogenes methylates the 2'-O atom of U2479 of the 23S ribosomal RNA. AviRb is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349980 Cd Length: 148 Bit Score: 59.71 E-value: 3.08e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384468738 114 VLLDRVTDPHNVGAILRSAEVFGAQAVIGTLHHSAPETGALAKTASGALERQPYLR---ERNLSDTIQALQE--MGYLVL 188
Cdd:cd18107 3 VLFDRPTSPGNLGTIIRSADALGAHGLVVTGHAADVYDPKTIRASTGSLFSLPIVRvpsNRELEDWVEARKArgTPLQLV 82
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 384468738 189 GLDGDAEdtVEAALDGLRdRAVALVLGAEGPGLRQKTRETVDRLVRIDFAGGFGSLNVSN 248
Cdd:cd18107 83 GTDEHGD--HQIADHDFT-RPTLLLIGNETAGLSAAWRELCDETVSIPMAGSASSLNAAC 139
|
|
| SpoU-like_RNA-MTase |
cd18104 |
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
113-248 |
4.76e-11 |
|
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349977 Cd Length: 146 Bit Score: 59.13 E-value: 4.76e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384468738 113 LVLLDRVTDPHNVGAILRSAEVFGAQAVIGTLHHSAPETGALAKTASGALERQPYLrERNLSDTIQALQEMGYLVLGLDG 192
Cdd:cd18104 2 ILVLEGLEKPGNLGAILRSADAAGADAVILCDPKTDLFNPNVIRASLGAVFTLPVA-EASSEETLAWLKENKIRILATTP 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 384468738 193 DAEDTVEAALdgLRDRaVALVLGAEGPGLRQKTRETVDRLVRIDFAGGFGSLNVSN 248
Cdd:cd18104 81 KAEKLYYEAD--LRGP-IAIVVGSESEGLSEFWLKAADERVRIPMAGQADSLNVSV 133
|
|
| SpoU-like |
cd18096 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
114-247 |
3.34e-10 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349969 Cd Length: 140 Bit Score: 56.84 E-value: 3.34e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384468738 114 VLLDRVTDPHNVGAILRSAEVFGAQAV--IGTLHHSApeTGALaktasGALERQPYLRERNLSDTIQALQEMGYLVLGLD 191
Cdd:cd18096 3 LVLHNVAKRHNIGTIVRSANAFGVKEVhlVGRRKFNP--FGAM-----GTDRHVKFRHFDTLAEAKEYLKERGIRLVGVE 75
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 384468738 192 --GDAEDTVEAALDGlrdrAVALVLGAEGPGLRQKTRETVDRLVRI-DFAGGFGSLNVS 247
Cdd:cd18096 76 ivPGAEPIETHPFPG----DTAFVLGNEGTGLSDEQLAICDGFVYIpQYGSGTASLNVS 130
|
|
| SpoU_sub_bind |
smart00967 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
25-93 |
9.08e-07 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 214943 [Multi-domain] Cd Length: 70 Bit Score: 45.22 E-value: 9.08e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 384468738 25 LFGLHAVRDALLNPRREKlRLIVTPNAELRLADAIAAA---GITPDVQDPRRFDAPLDPQsVHQGAALEAKP 93
Cdd:smart00967 1 IEGRHAVEEALKSGRRIK-ELYLTEGRAERLKELLKLAkerGIKVIEVSKKELDKLSGTA-NHQGVVAVVKP 70
|
|
| PRK11081 |
PRK11081 |
tRNA guanosine-2'-O-methyltransferase; Provisional |
108-250 |
5.80e-06 |
|
tRNA guanosine-2'-O-methyltransferase; Provisional
Pssm-ID: 236837 [Multi-domain] Cd Length: 229 Bit Score: 46.14 E-value: 5.80e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384468738 108 TRPPRL-VLLDRVTDPHNVGAILRSAEVFGaqavIGTLHHSAPETGA--LAKTASGALERQPYLRERNLSDTIQAL--QE 182
Cdd:PRK11081 15 RRQPDLtVCMEQVHKPHNVSAIIRTADAVG----VHEVHAVWPGSRMrtMGSTAAGSNSWVQVKTHRTIGDAVAHLkgQG 90
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 384468738 183 MGYLVLGLDGDAEDtveaaldgLRD----RAVALVLGAEGPGLRQKTRETVDRLVRIDFAGGFGSLNVSNAA 250
Cdd:PRK11081 91 MQILATHLSDTAVD--------FREidytRPTCILMGQEKTGISQEALALADQDIIIPMIGMVQSLNVSVAS 154
|
|
| SpoU-like_TRM3-like |
cd18091 |
SAM-dependent tRNA methylase related to TRM3; Yeast tRNA (guanosine(18)-2'-O) ... |
115-248 |
6.57e-05 |
|
SAM-dependent tRNA methylase related to TRM3; Yeast tRNA (guanosine(18)-2'-O)-methyltransferase TRM3 catalyzes the formation of 2'-O-methylguanosine at position 18 (Gm18) in various tRNAs. TRM3 is similar to C-terminal domain of TAR (HIV-1) RNA binding protein 1 (TARBP1), a protein binding to TAR, which functions as a RNA regulatory signal by forming a stable stem-loop structure to which transactivator protein Tat binds. The role of TARBP1 is believed to be to disengage RNA polymerase II from TAR during transcriptional elongation. TRM3 and the C-terminal methyltransferase domain of TARBP1 are members of the SPOUT methyltransferase superfamily.
Pssm-ID: 349964 Cd Length: 145 Bit Score: 41.75 E-value: 6.57e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384468738 115 LLDRvtdPHNVGAILRSAEVFGAQAVIgtLHHSA----PETGALAKTASGALERQpYLRERNLSDTIQALQEMGYLVLGL 190
Cdd:cd18091 7 LIDK---PPNLGGLCRTCEIFGVSKLV--LPNLAvvedKQFKALSVSAEKWLPIE-EVKPEDLLPYLKEKKQEGYTIVGL 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 384468738 191 dgdaEDTVEA-ALDGLR-DRAVALVLGAEGPGLRQKTRETVDRLVRIDFAGGFGSLNVSN 248
Cdd:cd18091 81 ----EQTANSvSLHDFQfPKKTVLVLGNEKEGIPAELLSLLDVCVEIPQLGVIRSLNVHV 136
|
|
| SpoU_sub_bind |
pfam08032 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
24-94 |
7.06e-05 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 429793 [Multi-domain] Cd Length: 74 Bit Score: 40.30 E-value: 7.06e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 384468738 24 WLFGLHAVRDALLNpRREKLRLIVTPNAELR----LADAIAAAGITPDVQDPRRFDApLDPQSVHQGAALEAKPL 94
Cdd:pfam08032 1 LIYGRHAVLEALKS-GPEIKKLYLTEGRRDPrlkeLLKLAKERGIKVEEVDRKKLDK-LSGTANHQGVVAEVKPY 73
|
|
| SpoU-like_TrmJ |
cd18093 |
SAM-dependent tRNA methylase related to TrmJ; tRNA methyltransferase TrmJ catalyzes the methyl ... |
114-247 |
5.29e-04 |
|
SAM-dependent tRNA methylase related to TrmJ; tRNA methyltransferase TrmJ catalyzes the methyl transfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH at position 32 in both tRNASer1 and tRNAGln2. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349966 Cd Length: 153 Bit Score: 39.40 E-value: 5.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384468738 114 VLLDRVTDPHNVGAILRSAEVFGAQA--VIGTlhHSAPETGALAKTASGAlerQPYLRERNLSDTI-QALQEMGYLV--- 187
Cdd:cd18093 3 VVLVEPQHPGNIGAVARAMKNFGLSDlrLVNP--RCDDPEEAARALASGA---EDVLENAKVYDTLeEALADCDLVVatt 77
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 384468738 188 --LGLDG----DAEDTVEAALDGLRDRAVALVLGAEGPGLrqkTRETV---DRLVRIDFAGGFGSLNVS 247
Cdd:cd18093 78 arPRGLRrpllTPRELAELLKEHAAGGKVALVFGREDSGL---TNEELalcDLLVTIPTNPEYPSLNLA 143
|
|
| SpoU-like |
cd18098 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
116-247 |
6.29e-04 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349971 Cd Length: 138 Bit Score: 38.78 E-value: 6.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384468738 116 LDRVTDPHNVGAILRSAEVFGAQAVIgtlhhsapetgalaktASGAlerqPYLRERNLSDTIQALQEMGYLVL-----GL 190
Cdd:cd18098 5 IENPKTPKNVGTLWRAAGCLGASFVF----------------TIGA----RYKRRKQSTDTSKAWRHIPLFHYddledLA 64
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 384468738 191 DGDAEDTVEAALDgLRDRAVAL-----------VLGAEGPGLRQKTRETVDRLVRIDfagGFGSLNVS 247
Cdd:cd18098 65 EPLPFGAVLVAVE-LTEGATPLpdfkhpdravyLLGPEDGGLPQEVLARCHHVVYLP---TRGSLNVA 128
|
|
| SpoU-like_RNMTL1 |
cd18106 |
SAM-dependent rRNA methylase related to RNMTL1; RNMTL1 (also known as HC90, MRM3 and RMTL1) ... |
114-143 |
1.85e-03 |
|
SAM-dependent rRNA methylase related to RNMTL1; RNMTL1 (also known as HC90, MRM3 and RMTL1) catalyzes the methylation of 2'-O-ribose residues G1370 to GmG residue of the mitochondrial 16S rRNA. RNMTL1 is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349979 Cd Length: 148 Bit Score: 37.62 E-value: 1.85e-03
10 20 30
....*....|....*....|....*....|
gi 384468738 114 VLLDRVTDPHNVGAILRSAEVFGAQAVIGT 143
Cdd:cd18106 3 VICDNIRDPGNLGSILRSAAAAGCSKVLLT 32
|
|
| SpoU-like_NHR |
cd18108 |
Nosiheptide-resistance methyltransferase (NHR); Nosiheptide-resistance methyltransferase (NHR) ... |
113-248 |
3.62e-03 |
|
Nosiheptide-resistance methyltransferase (NHR); Nosiheptide-resistance methyltransferase (NHR) confers resistance to the thiazole antibiotic nosiheptide via catalyzing 2'O-methylation of 23S rRNA at the nucleotide A1067. NHR is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349981 Cd Length: 144 Bit Score: 37.07 E-value: 3.62e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 384468738 113 LVLLDRVTDPHNVGAILRSAEVFGAQAVIgtLHHSAPETGA---LAKTASGALERQP-YLRERnlSDTIQALQEMGYLVL 188
Cdd:cd18108 2 VVVLDGVRIVGNIGAIVRTSLALGAAGIV--LVDSDLATVAdrrLLRASRGYVFSLPvVLADR--EEAVAFLRDNDIPLM 77
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 384468738 189 GLDGDAeDTVEAALDGLRDRaVALVLGAEGPGLRQKTRETVDRLVRIDFAGGFGSLNVSN 248
Cdd:cd18108 78 TLDADG-DVPVKELGDRPDR-LALVFGSEKGGPSGLFEEAAAGTVSIPMSSSTESLNVSV 135
|
|
| |
