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Conserved domains on  [gi|452000400|gb|EMD92861|]
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hypothetical protein COCHEDRAFT_1133030 [Bipolaris maydis C5]

Protein Classification

hydantoinase/oxoprolinase family protein( domain architecture ID 1004610)

hydantoinase/oxoprolinase family protein is involved in the hydrolysis of 5-membered rings via hydrolysis of their internal imide bonds; such as 5-oxoprolinase that catalyzes the hydrolysis of 5-oxoproline (5-OP) to L-glutamate

EC:  3.5.2.-
Gene Ontology:  GO:0005524|GO:0016812

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLN02666 super family cl33539
5-oxoprolinase
 4-1323 0e+00

5-oxoprolinase


The actual alignment was detected with superfamily member PLN02666:

Pssm-ID: 215358 [Multi-domain]  Cd Length: 1275  Bit Score: 1862.46  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400    4 PKIAQRGIRIAIDRGGTFTDCVGN-PGtgkMEDDVLIKLLSVDPSNYDDAPLEGIRRLLSRFTGTEIPRGQPLDTSKIES 82
Cdd:PLN02666    3 GSRGSRKFRFCIDRGGTFTDVYAEvPG---GSDFRVLKLLSVDPANYDDAPREGIRRILEEVTGKKIPRSAKIPTERIEW 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400   83 IRMGTTVATNALLERKGEDIAMVVTKGFKDCLEIGNQSRPNIFALDIRKPEVLYKKVVEIDERVTLedyaedpernqtqA 162
Cdd:PLN02666   80 IRMGTTVATNALLERKGERIALCVTKGFKDLLQIGNQARPNIFDLTVSKPSNLYEEVVEVDERVVL-------------A 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  163 ASIEEAGDEAELVKGLSGETVRILQRPQEQAIRKQLQEVYDSGLKSIAVCLMHGYTYPKHEALVGKIAREIGFEHVSLSH 242
Cdd:PLN02666  147 LEEDGDDAGGSVVKGVTGELVEVVKPLDEEALRPLLQGLLDKGIRSLAVVLMHSYTYPAHERAVGKLARSMGFKQVSLSS 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  243 ELMPMIKLVPRATSACADAYLTPAIRKYIDGFSKGFEGGLGTKSVkreegskgarcEFMQSDGGLVDVDMFSGLKAILSG 322
Cdd:PLN02666  227 ALVPMVRAVPRGHTASVDAYLTPVIKEYLSGFLSGFDDGLGDVNV-----------LFMQSDGGLTPESRFSGHKAILSG 295

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  323 PAGGVVGYALTSYDPQTKIPVIGFDMGGTSTDVSRYgAGRYDHVFETTTAGVTIQSPQLDINTVAAGGGSRLFWKNGLFV 402
Cdd:PLN02666  296 PAGGVVGYAQTTFGLETEKPVIGFDMGGTSTDVSRY-DGSYEQVLETQTAGVIIQAPQLDINTVAAGGGSKLKFQFGAFR 374

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  403 VGPESASAHPGPACYRKGGPLTITDANLFLGRLLPDFFPKIFGKNEDEGLDAQASEKLFKELADQINKEIAGGNKE-KEM 481
Cdd:PLN02666  375 VGPESVGAHPGPVCYRKGGELAVTDANLVLGRVIPDYFPSIFGPNEDEPLDLEATRAAFEALAAQINSYRKSQDPSaKDM 454

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  482 SLDDIANGFIKIANETMTRPIRSLTEARGHDTSKHRLATFGGAGGQHAVAIAEALGISQILVHRYSSVLSAYGMALADVV 561
Cdd:PLN02666  455 SVEEVALGFVRVANEAMCRPIRQLTEMKGYETANHALACFGGAGPQHACAIARALGMSEVFVHRYCGILSAYGMGLADVV 534

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  562 DERQEPESKIWSDEkdVRSYLQAKMADLKSKSTATLKDQGFDEEHIHFEEYLNLRYRGTESALMIIKPtkeeaqEDYDGD 641
Cdd:PLN02666  535 AEAQEPYAAVYGPE--SLAEASRREDALAEKVRQKLQEQGFREDNITTETYLNLRYEGTDTAIMVAEP------ENGDGS 606

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  642 EWAFGKAFIKQHEQEFGFTLPDRDIIVDDVRARGIGKTfEGLEKSVDQQLKEIKPKDLqgdakryDTRKVFFEGGRQDTS 721
Cdd:PLN02666  607 DGDYAAAFVKLFRREYGFKLQNRDILIDDVRVRGIGVT-NILKPLPLDAASGGLPEPE-------RTTKVYFENGWHDTP 678

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  722 VYKLEDLEVGDRLKGPAIIADGTQTIVVTPGATALIINTH-VVINIGET----EDQEKQIDTKEVDPILLSIFAHRFMAI 796
Cdd:PLN02666  679 VYKLENLGPGHEIPGPAIIMNGNSTVVVEPGCKAIVTKYGnIKIEVENSaeqsAEETVKAAEKKADVVQLSIFNHRFMGI 758

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  797 AEQMGRALQKTSVSTNVKERLDYSCALFDADGGLVANAPHLPVHLGSMSTCVRKQAAIWKGKLKKGDVLVSNHPMFGGTH 876
Cdd:PLN02666  759 AEQMGRTLQRTSISTNIKERLDFSCALFGPDGGLVANAPHVPVHLGAMSSTVRWQLEYWGENLNEGDVLVTNHPQAGGSH 838

                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  877 LPDITVITPAFSGDNIVFYVASRAHHADIGGILPGSMPPASKELYQEGAAIKSEKLVSEGHFNEERITELLL--DEPGQY 954
Cdd:PLN02666  839 LPDITVITPVFRDGKIVFFVASRGHHADIGGITPGSMPPFSKTIWEEGAAIKAFKLVEGGVFQEEGITKLLQapGSDETA 918

                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  955 PGCSGTRCLSDNINDLKAQVAANQKGINLISTLMSDYGEEVVKFYMTNIQANAEKSVRALLKDVYKRFEGQD-------- 1026
Cdd:PLN02666  919 PKIPGTRRLQDNLSDLRAQVAANQRGISLIKELIDEYGLGTVQAYMGHVQANAELAVREMLKSVAARVSSESptfgdgss 998

                        1050      1060      1070      1080      1090      1100      1110      1120
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400 1027 --LSAEEFMDDGSPIRLKVSIDPEKGEAVFDFSGTGPEVYGNINAPEAVTYSAIIYCLRCLISEDIPLNQGCLKPIHVLI 1104
Cdd:PLN02666  999 vtLEAEDYMDDGSPIHLTLTIDRRKGSAVFDFEGTSPEVYGNWNAPPAVTAAAVIYCLRCLVDVDIPLNQGCLAPVTIRI 1078

                        1130      1140      1150      1160      1170      1180      1190      1200
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400 1105 PKKSFLSPSDNAAVVGGNVLTSQRVTDVVLKAFRACAASQGDCNNLtfgfggttfgegaksgerkeTKG---FGYYETIA 1181
Cdd:PLN02666 1079 PPGSFLSPSDKAAVVGGNVLTSQRVTDVVLTAFQACACSQGCMNNL--------------------TFGddtFGYYETIA 1138

                        1210      1220      1230      1240      1250      1260      1270      1280
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400 1182 GGSGAGPTWNGTSGVHTHMTNTRITDSEVFERRYPVLLREFSLRQGSAGRGMHIGGEGVIRDIEFRIPVQVSILSERRVY 1261
Cdd:PLN02666 1139 GGAGAGPTWDGTSGVQCHMTNTRITDPEILERRYPVLLHRFGLREGSGGDGLHRGGDGVVREIEFRRPVTVSILSERRVH 1218

                        1290      1300      1310      1320      1330      1340
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 452000400 1262 HPYGMEGGGDAACGLNIWVRKtlekkdaardrkedvEYRYINLGAKNTASMRPGERIIIHTP 1323
Cdd:PLN02666 1219 APRGLAGGGDGARGANLLIRK---------------DGRRVNLGGKNTVHVEAGERLRILTP 1265
 
Name Accession Description Interval E-value
PLN02666 PLN02666
5-oxoprolinase
 4-1323 0e+00

5-oxoprolinase


Pssm-ID: 215358 [Multi-domain]  Cd Length: 1275  Bit Score: 1862.46  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400    4 PKIAQRGIRIAIDRGGTFTDCVGN-PGtgkMEDDVLIKLLSVDPSNYDDAPLEGIRRLLSRFTGTEIPRGQPLDTSKIES 82
Cdd:PLN02666    3 GSRGSRKFRFCIDRGGTFTDVYAEvPG---GSDFRVLKLLSVDPANYDDAPREGIRRILEEVTGKKIPRSAKIPTERIEW 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400   83 IRMGTTVATNALLERKGEDIAMVVTKGFKDCLEIGNQSRPNIFALDIRKPEVLYKKVVEIDERVTLedyaedpernqtqA 162
Cdd:PLN02666   80 IRMGTTVATNALLERKGERIALCVTKGFKDLLQIGNQARPNIFDLTVSKPSNLYEEVVEVDERVVL-------------A 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  163 ASIEEAGDEAELVKGLSGETVRILQRPQEQAIRKQLQEVYDSGLKSIAVCLMHGYTYPKHEALVGKIAREIGFEHVSLSH 242
Cdd:PLN02666  147 LEEDGDDAGGSVVKGVTGELVEVVKPLDEEALRPLLQGLLDKGIRSLAVVLMHSYTYPAHERAVGKLARSMGFKQVSLSS 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  243 ELMPMIKLVPRATSACADAYLTPAIRKYIDGFSKGFEGGLGTKSVkreegskgarcEFMQSDGGLVDVDMFSGLKAILSG 322
Cdd:PLN02666  227 ALVPMVRAVPRGHTASVDAYLTPVIKEYLSGFLSGFDDGLGDVNV-----------LFMQSDGGLTPESRFSGHKAILSG 295

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  323 PAGGVVGYALTSYDPQTKIPVIGFDMGGTSTDVSRYgAGRYDHVFETTTAGVTIQSPQLDINTVAAGGGSRLFWKNGLFV 402
Cdd:PLN02666  296 PAGGVVGYAQTTFGLETEKPVIGFDMGGTSTDVSRY-DGSYEQVLETQTAGVIIQAPQLDINTVAAGGGSKLKFQFGAFR 374

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  403 VGPESASAHPGPACYRKGGPLTITDANLFLGRLLPDFFPKIFGKNEDEGLDAQASEKLFKELADQINKEIAGGNKE-KEM 481
Cdd:PLN02666  375 VGPESVGAHPGPVCYRKGGELAVTDANLVLGRVIPDYFPSIFGPNEDEPLDLEATRAAFEALAAQINSYRKSQDPSaKDM 454

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  482 SLDDIANGFIKIANETMTRPIRSLTEARGHDTSKHRLATFGGAGGQHAVAIAEALGISQILVHRYSSVLSAYGMALADVV 561
Cdd:PLN02666  455 SVEEVALGFVRVANEAMCRPIRQLTEMKGYETANHALACFGGAGPQHACAIARALGMSEVFVHRYCGILSAYGMGLADVV 534

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  562 DERQEPESKIWSDEkdVRSYLQAKMADLKSKSTATLKDQGFDEEHIHFEEYLNLRYRGTESALMIIKPtkeeaqEDYDGD 641
Cdd:PLN02666  535 AEAQEPYAAVYGPE--SLAEASRREDALAEKVRQKLQEQGFREDNITTETYLNLRYEGTDTAIMVAEP------ENGDGS 606

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  642 EWAFGKAFIKQHEQEFGFTLPDRDIIVDDVRARGIGKTfEGLEKSVDQQLKEIKPKDLqgdakryDTRKVFFEGGRQDTS 721
Cdd:PLN02666  607 DGDYAAAFVKLFRREYGFKLQNRDILIDDVRVRGIGVT-NILKPLPLDAASGGLPEPE-------RTTKVYFENGWHDTP 678

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  722 VYKLEDLEVGDRLKGPAIIADGTQTIVVTPGATALIINTH-VVINIGET----EDQEKQIDTKEVDPILLSIFAHRFMAI 796
Cdd:PLN02666  679 VYKLENLGPGHEIPGPAIIMNGNSTVVVEPGCKAIVTKYGnIKIEVENSaeqsAEETVKAAEKKADVVQLSIFNHRFMGI 758

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  797 AEQMGRALQKTSVSTNVKERLDYSCALFDADGGLVANAPHLPVHLGSMSTCVRKQAAIWKGKLKKGDVLVSNHPMFGGTH 876
Cdd:PLN02666  759 AEQMGRTLQRTSISTNIKERLDFSCALFGPDGGLVANAPHVPVHLGAMSSTVRWQLEYWGENLNEGDVLVTNHPQAGGSH 838

                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  877 LPDITVITPAFSGDNIVFYVASRAHHADIGGILPGSMPPASKELYQEGAAIKSEKLVSEGHFNEERITELLL--DEPGQY 954
Cdd:PLN02666  839 LPDITVITPVFRDGKIVFFVASRGHHADIGGITPGSMPPFSKTIWEEGAAIKAFKLVEGGVFQEEGITKLLQapGSDETA 918

                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  955 PGCSGTRCLSDNINDLKAQVAANQKGINLISTLMSDYGEEVVKFYMTNIQANAEKSVRALLKDVYKRFEGQD-------- 1026
Cdd:PLN02666  919 PKIPGTRRLQDNLSDLRAQVAANQRGISLIKELIDEYGLGTVQAYMGHVQANAELAVREMLKSVAARVSSESptfgdgss 998

                        1050      1060      1070      1080      1090      1100      1110      1120
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400 1027 --LSAEEFMDDGSPIRLKVSIDPEKGEAVFDFSGTGPEVYGNINAPEAVTYSAIIYCLRCLISEDIPLNQGCLKPIHVLI 1104
Cdd:PLN02666  999 vtLEAEDYMDDGSPIHLTLTIDRRKGSAVFDFEGTSPEVYGNWNAPPAVTAAAVIYCLRCLVDVDIPLNQGCLAPVTIRI 1078

                        1130      1140      1150      1160      1170      1180      1190      1200
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400 1105 PKKSFLSPSDNAAVVGGNVLTSQRVTDVVLKAFRACAASQGDCNNLtfgfggttfgegaksgerkeTKG---FGYYETIA 1181
Cdd:PLN02666 1079 PPGSFLSPSDKAAVVGGNVLTSQRVTDVVLTAFQACACSQGCMNNL--------------------TFGddtFGYYETIA 1138

                        1210      1220      1230      1240      1250      1260      1270      1280
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400 1182 GGSGAGPTWNGTSGVHTHMTNTRITDSEVFERRYPVLLREFSLRQGSAGRGMHIGGEGVIRDIEFRIPVQVSILSERRVY 1261
Cdd:PLN02666 1139 GGAGAGPTWDGTSGVQCHMTNTRITDPEILERRYPVLLHRFGLREGSGGDGLHRGGDGVVREIEFRRPVTVSILSERRVH 1218

                        1290      1300      1310      1320      1330      1340
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 452000400 1262 HPYGMEGGGDAACGLNIWVRKtlekkdaardrkedvEYRYINLGAKNTASMRPGERIIIHTP 1323
Cdd:PLN02666 1219 APRGLAGGGDGARGANLLIRK---------------DGRRVNLGGKNTVHVEAGERLRILTP 1265
Hydantoinase_B pfam02538
Hydantoinase B/oxoprolinase; This family includes N-methylhydaintoinase B which converts ...
 783-1323 0e+00

Hydantoinase B/oxoprolinase; This family includes N-methylhydaintoinase B which converts hydantoin to N-carbamyl-amino acids, and 5-oxoprolinase EC:3.5.2.9 which catalyzes the formation of L-glutamate from 5-oxo-L-proline. These enzymes are part of the oxoprolinase family and are related to pfam01968.


Pssm-ID: 460583  Cd Length: 507  Bit Score: 738.13  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400   783 PILLSIFAHRFMAIAEQMGRALQKTSVSTNVKERLDYSCALFDADGGLVANAPHLPVHLGSMSTCVRKQAAIwKGKLKKG 862
Cdd:pfam02538    1 PITLEVFRNRLMSIAEEMGRTLQRTAFSPNIKERLDFSCAIFDADGRLVAQAPHIPVHLGSMSFAVKAVIEY-GGDLRPG 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400   863 DVLVSNHPMFGGTHLPDITVITPAFSGDNIVFYVASRAHHADIGGILPGSMPPASKELYQEGAAIKSEKLVSEGHFNEEr 942
Cdd:pfam02538   80 DVFITNDPYAGGTHLPDITVITPVFHDGELVFFVASRGHHADIGGIVPGSMPPDATEIYQEGLRIPPVKLVRRGVLNED- 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400   943 ITELLldepgqypgCSGTRCLSDNINDLKAQVAANQKGINLISTLMSDYGEEVVKFYMTNIQANAEKSVRALLKDVYKRf 1022
Cdd:pfam02538  159 VLRLL---------LANSRTPEDNLGDLKAQIAANRVGERRLLELIDEYGLDTVLAAMDEIQDYAERAVRAAIAALPDG- 228

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  1023 egqDLSAEEFMDDGSPIRLKVSIDPEKGEAVFDFSGTGPEVYGNINAPEAVTYSAIIYCLRCLISEDIPLNQGCLKPIHV 1102
Cdd:pfam02538  229 ---TYEAEDYLDDGVPIPIRVTVTIDGDEATVDFTGTSPQVPGNINAPLAVTHSAVIYALRCLVDPDIPLNAGCLRPIEV 305

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  1103 LIPKKSFLSPSDNAAVVGGNVLTSQRVTDVVLKAF------RACAASQGDCNNLTfgfggttfgeGAKSGERKETKGFGY 1176
Cdd:pfam02538  306 IAPEGSLLNPSPPAAVVGGNVETSQRIVDVVLGALaqalpeRVPAASQGTMNNLT----------FGGVDPRGGGRFFGY 375

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  1177 YETIAGGSGAGPTWNGTSGVHTHMTNTRITDSEVFERRYPVLLREFSLRQGSAGRGMHIGGEGVIRDIEFRIP-VQVSIL 1255
Cdd:pfam02538  376 YETIGGGSGARPGGDGLDGVHVHMTNTRNTPVEVLERRYPVLVERYELRPDSGGAGRYRGGDGVVREIEFLAPdATVSIL 455

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 452000400  1256 SERRVYHPYGMEGGGDAACGlniwvrktlekkdaardrkedveyrYINLGAKNTA-SMRPGERIIIHTP 1323
Cdd:pfam02538  456 SERRVFPPWGLAGGEPGAPG-------------------------RVNLGGKATDvELKPGDRLRIETP 499
HyuA COG0145
N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit [Amino acid transport ...
 13-755 0e+00

N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit [Amino acid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 439915 [Multi-domain]  Cd Length: 678  Bit Score: 675.27  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400   13 IAIDRGGTFTDCVGNPGTGKMeddVLIKLLSvDPSNYDDAPLEGIRRLLSRftgteiprgQPLDTSKIESIRMGTTVATN 92
Cdd:COG0145     1 VGVDVGGTFTDVVAVDEDGRL---RTHKVLS-TPEDPSDGVLEGIRELLED---------AGIPLAEIDLVVHGTTVATN 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400   93 ALLERKGEDIAMVVTKGFKDCLEIGNQSRPNIFALDIRKPEVLYKK--VVEIDERVtledyaedpernqtqaasieeagd 170
Cdd:COG0145    68 ALLERKGARTGLITTRGFRDVLEIGRQNRPDLYDLFIEKPEPLVPRrlRFEVRERI------------------------ 123

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  171 eaeLVKGlsgetvRILQRPQEQAIRKQLQEVYDSGLKSIAVCLMHGYTYPKHEALVGKIARE-IGFEHVSLSHELMPMIK 249
Cdd:COG0145   124 ---DADG------EVLTPLDEAEVRAAARELRAAGVEAVAVCFLHSYRNPAHERRAAEILREeLPDVPVSLSSEVSPEIR 194

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  250 LVPRATSACADAYLTPAIRKYIDGFSKGFegglgtksvkREEGSKGaRCEFMQSDGGLVDVDMFS--GLKAILSGPAGGV 327
Cdd:COG0145   195 EYERTSTTVVNAYLSPILRRYLDRLEARL----------RERGFGG-PLLIMQSNGGLASAEAAArrPVRTILSGPAGGV 263

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  328 VGYALTSydPQTKIP-VIGFDMGGTSTDVSRYGAGRYDHVFETTTAGVTIQSPQLDINTVAAGGGSRLfW--KNGLFVVG 404
Cdd:COG0145   264 VGAAALA--RAAGFDnVITFDMGGTSTDVSLIEDGEPERTTETEVAGYPVRVPMVDIHTVGAGGGSIA-WvdAGGRLRVG 340

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  405 PESASAHPGPACYRKGGP-LTITDANLFLGRLLPDFFpkIFGkneDEGLDAQASEKLFKELADQINkeiaggnkekeMSL 483
Cdd:COG0145   341 PESAGADPGPACYGRGGTePTVTDANLVLGRLDPDNF--LGG---RMPLDVEAARAAIEKLADPLG-----------LSV 404

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  484 DDIANGFIKIANETMTRPIRSLTEARGHDTSKHRLATFGGAGGQHAVAIAEALGISQILVHRYSSVLSAYGMALADVVDE 563
Cdd:COG0145   405 EEAAEGILRIANENMANAIRKVSVERGYDPRDFTLVAFGGAGPLHACALAEELGIPRVIVPPAAGVLSALGMLLADIRHD 484

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  564 RQepESKIWSDEKDVRSYLQAKMADLKSKSTATLKDQGFDEEHIHFEEYLNLRYRGTESALMIIKPTKEEAQEDYDgdew 643
Cdd:COG0145   485 YV--RSVEAPLDDADLAELNAAFAELEAEARAELAAEGVAAEDIRVERSADMRYAGQGHELTVPLPAGRLDAADLA---- 558

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  644 AFGKAFIKQHEQEFGFTLPDRDIIVDDVRARGIGKTfeglEKSVDQQLkeikPKDLQGDAKRYDTRKVFFEGGRQDTSVY 723
Cdd:COG0145   559 ALRAAFHAAHERRYGFALPDAPVEIVNLRVEAIGPV----PKPELPRL----PPGGDAAPAPKGTRPVYFDGGWVDTPVY 630

                         730       740       750
                  ....*....|....*....|....*....|..
gi 452000400  724 KLEDLEVGDRLKGPAIIADGTQTIVVTPGATA 755
Cdd:COG0145   631 DREALPPGDRIAGPAIIEEPDTTTVVPPGWRA 662
 
Name Accession Description Interval E-value
PLN02666 PLN02666
5-oxoprolinase
 4-1323 0e+00

5-oxoprolinase


Pssm-ID: 215358 [Multi-domain]  Cd Length: 1275  Bit Score: 1862.46  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400    4 PKIAQRGIRIAIDRGGTFTDCVGN-PGtgkMEDDVLIKLLSVDPSNYDDAPLEGIRRLLSRFTGTEIPRGQPLDTSKIES 82
Cdd:PLN02666    3 GSRGSRKFRFCIDRGGTFTDVYAEvPG---GSDFRVLKLLSVDPANYDDAPREGIRRILEEVTGKKIPRSAKIPTERIEW 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400   83 IRMGTTVATNALLERKGEDIAMVVTKGFKDCLEIGNQSRPNIFALDIRKPEVLYKKVVEIDERVTLedyaedpernqtqA 162
Cdd:PLN02666   80 IRMGTTVATNALLERKGERIALCVTKGFKDLLQIGNQARPNIFDLTVSKPSNLYEEVVEVDERVVL-------------A 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  163 ASIEEAGDEAELVKGLSGETVRILQRPQEQAIRKQLQEVYDSGLKSIAVCLMHGYTYPKHEALVGKIAREIGFEHVSLSH 242
Cdd:PLN02666  147 LEEDGDDAGGSVVKGVTGELVEVVKPLDEEALRPLLQGLLDKGIRSLAVVLMHSYTYPAHERAVGKLARSMGFKQVSLSS 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  243 ELMPMIKLVPRATSACADAYLTPAIRKYIDGFSKGFEGGLGTKSVkreegskgarcEFMQSDGGLVDVDMFSGLKAILSG 322
Cdd:PLN02666  227 ALVPMVRAVPRGHTASVDAYLTPVIKEYLSGFLSGFDDGLGDVNV-----------LFMQSDGGLTPESRFSGHKAILSG 295

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  323 PAGGVVGYALTSYDPQTKIPVIGFDMGGTSTDVSRYgAGRYDHVFETTTAGVTIQSPQLDINTVAAGGGSRLFWKNGLFV 402
Cdd:PLN02666  296 PAGGVVGYAQTTFGLETEKPVIGFDMGGTSTDVSRY-DGSYEQVLETQTAGVIIQAPQLDINTVAAGGGSKLKFQFGAFR 374

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  403 VGPESASAHPGPACYRKGGPLTITDANLFLGRLLPDFFPKIFGKNEDEGLDAQASEKLFKELADQINKEIAGGNKE-KEM 481
Cdd:PLN02666  375 VGPESVGAHPGPVCYRKGGELAVTDANLVLGRVIPDYFPSIFGPNEDEPLDLEATRAAFEALAAQINSYRKSQDPSaKDM 454

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  482 SLDDIANGFIKIANETMTRPIRSLTEARGHDTSKHRLATFGGAGGQHAVAIAEALGISQILVHRYSSVLSAYGMALADVV 561
Cdd:PLN02666  455 SVEEVALGFVRVANEAMCRPIRQLTEMKGYETANHALACFGGAGPQHACAIARALGMSEVFVHRYCGILSAYGMGLADVV 534

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  562 DERQEPESKIWSDEkdVRSYLQAKMADLKSKSTATLKDQGFDEEHIHFEEYLNLRYRGTESALMIIKPtkeeaqEDYDGD 641
Cdd:PLN02666  535 AEAQEPYAAVYGPE--SLAEASRREDALAEKVRQKLQEQGFREDNITTETYLNLRYEGTDTAIMVAEP------ENGDGS 606

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  642 EWAFGKAFIKQHEQEFGFTLPDRDIIVDDVRARGIGKTfEGLEKSVDQQLKEIKPKDLqgdakryDTRKVFFEGGRQDTS 721
Cdd:PLN02666  607 DGDYAAAFVKLFRREYGFKLQNRDILIDDVRVRGIGVT-NILKPLPLDAASGGLPEPE-------RTTKVYFENGWHDTP 678

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  722 VYKLEDLEVGDRLKGPAIIADGTQTIVVTPGATALIINTH-VVINIGET----EDQEKQIDTKEVDPILLSIFAHRFMAI 796
Cdd:PLN02666  679 VYKLENLGPGHEIPGPAIIMNGNSTVVVEPGCKAIVTKYGnIKIEVENSaeqsAEETVKAAEKKADVVQLSIFNHRFMGI 758

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  797 AEQMGRALQKTSVSTNVKERLDYSCALFDADGGLVANAPHLPVHLGSMSTCVRKQAAIWKGKLKKGDVLVSNHPMFGGTH 876
Cdd:PLN02666  759 AEQMGRTLQRTSISTNIKERLDFSCALFGPDGGLVANAPHVPVHLGAMSSTVRWQLEYWGENLNEGDVLVTNHPQAGGSH 838

                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  877 LPDITVITPAFSGDNIVFYVASRAHHADIGGILPGSMPPASKELYQEGAAIKSEKLVSEGHFNEERITELLL--DEPGQY 954
Cdd:PLN02666  839 LPDITVITPVFRDGKIVFFVASRGHHADIGGITPGSMPPFSKTIWEEGAAIKAFKLVEGGVFQEEGITKLLQapGSDETA 918

                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  955 PGCSGTRCLSDNINDLKAQVAANQKGINLISTLMSDYGEEVVKFYMTNIQANAEKSVRALLKDVYKRFEGQD-------- 1026
Cdd:PLN02666  919 PKIPGTRRLQDNLSDLRAQVAANQRGISLIKELIDEYGLGTVQAYMGHVQANAELAVREMLKSVAARVSSESptfgdgss 998

                        1050      1060      1070      1080      1090      1100      1110      1120
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400 1027 --LSAEEFMDDGSPIRLKVSIDPEKGEAVFDFSGTGPEVYGNINAPEAVTYSAIIYCLRCLISEDIPLNQGCLKPIHVLI 1104
Cdd:PLN02666  999 vtLEAEDYMDDGSPIHLTLTIDRRKGSAVFDFEGTSPEVYGNWNAPPAVTAAAVIYCLRCLVDVDIPLNQGCLAPVTIRI 1078

                        1130      1140      1150      1160      1170      1180      1190      1200
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400 1105 PKKSFLSPSDNAAVVGGNVLTSQRVTDVVLKAFRACAASQGDCNNLtfgfggttfgegaksgerkeTKG---FGYYETIA 1181
Cdd:PLN02666 1079 PPGSFLSPSDKAAVVGGNVLTSQRVTDVVLTAFQACACSQGCMNNL--------------------TFGddtFGYYETIA 1138

                        1210      1220      1230      1240      1250      1260      1270      1280
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400 1182 GGSGAGPTWNGTSGVHTHMTNTRITDSEVFERRYPVLLREFSLRQGSAGRGMHIGGEGVIRDIEFRIPVQVSILSERRVY 1261
Cdd:PLN02666 1139 GGAGAGPTWDGTSGVQCHMTNTRITDPEILERRYPVLLHRFGLREGSGGDGLHRGGDGVVREIEFRRPVTVSILSERRVH 1218

                        1290      1300      1310      1320      1330      1340
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 452000400 1262 HPYGMEGGGDAACGLNIWVRKtlekkdaardrkedvEYRYINLGAKNTASMRPGERIIIHTP 1323
Cdd:PLN02666 1219 APRGLAGGGDGARGANLLIRK---------------DGRRVNLGGKNTVHVEAGERLRILTP 1265
Hydantoinase_B pfam02538
Hydantoinase B/oxoprolinase; This family includes N-methylhydaintoinase B which converts ...
 783-1323 0e+00

Hydantoinase B/oxoprolinase; This family includes N-methylhydaintoinase B which converts hydantoin to N-carbamyl-amino acids, and 5-oxoprolinase EC:3.5.2.9 which catalyzes the formation of L-glutamate from 5-oxo-L-proline. These enzymes are part of the oxoprolinase family and are related to pfam01968.


Pssm-ID: 460583  Cd Length: 507  Bit Score: 738.13  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400   783 PILLSIFAHRFMAIAEQMGRALQKTSVSTNVKERLDYSCALFDADGGLVANAPHLPVHLGSMSTCVRKQAAIwKGKLKKG 862
Cdd:pfam02538    1 PITLEVFRNRLMSIAEEMGRTLQRTAFSPNIKERLDFSCAIFDADGRLVAQAPHIPVHLGSMSFAVKAVIEY-GGDLRPG 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400   863 DVLVSNHPMFGGTHLPDITVITPAFSGDNIVFYVASRAHHADIGGILPGSMPPASKELYQEGAAIKSEKLVSEGHFNEEr 942
Cdd:pfam02538   80 DVFITNDPYAGGTHLPDITVITPVFHDGELVFFVASRGHHADIGGIVPGSMPPDATEIYQEGLRIPPVKLVRRGVLNED- 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400   943 ITELLldepgqypgCSGTRCLSDNINDLKAQVAANQKGINLISTLMSDYGEEVVKFYMTNIQANAEKSVRALLKDVYKRf 1022
Cdd:pfam02538  159 VLRLL---------LANSRTPEDNLGDLKAQIAANRVGERRLLELIDEYGLDTVLAAMDEIQDYAERAVRAAIAALPDG- 228

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  1023 egqDLSAEEFMDDGSPIRLKVSIDPEKGEAVFDFSGTGPEVYGNINAPEAVTYSAIIYCLRCLISEDIPLNQGCLKPIHV 1102
Cdd:pfam02538  229 ---TYEAEDYLDDGVPIPIRVTVTIDGDEATVDFTGTSPQVPGNINAPLAVTHSAVIYALRCLVDPDIPLNAGCLRPIEV 305

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  1103 LIPKKSFLSPSDNAAVVGGNVLTSQRVTDVVLKAF------RACAASQGDCNNLTfgfggttfgeGAKSGERKETKGFGY 1176
Cdd:pfam02538  306 IAPEGSLLNPSPPAAVVGGNVETSQRIVDVVLGALaqalpeRVPAASQGTMNNLT----------FGGVDPRGGGRFFGY 375

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  1177 YETIAGGSGAGPTWNGTSGVHTHMTNTRITDSEVFERRYPVLLREFSLRQGSAGRGMHIGGEGVIRDIEFRIP-VQVSIL 1255
Cdd:pfam02538  376 YETIGGGSGARPGGDGLDGVHVHMTNTRNTPVEVLERRYPVLVERYELRPDSGGAGRYRGGDGVVREIEFLAPdATVSIL 455

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 452000400  1256 SERRVYHPYGMEGGGDAACGlniwvrktlekkdaardrkedveyrYINLGAKNTA-SMRPGERIIIHTP 1323
Cdd:pfam02538  456 SERRVFPPWGLAGGEPGAPG-------------------------RVNLGGKATDvELKPGDRLRIETP 499
HyuA COG0145
N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit [Amino acid transport ...
 13-755 0e+00

N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit [Amino acid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 439915 [Multi-domain]  Cd Length: 678  Bit Score: 675.27  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400   13 IAIDRGGTFTDCVGNPGTGKMeddVLIKLLSvDPSNYDDAPLEGIRRLLSRftgteiprgQPLDTSKIESIRMGTTVATN 92
Cdd:COG0145     1 VGVDVGGTFTDVVAVDEDGRL---RTHKVLS-TPEDPSDGVLEGIRELLED---------AGIPLAEIDLVVHGTTVATN 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400   93 ALLERKGEDIAMVVTKGFKDCLEIGNQSRPNIFALDIRKPEVLYKK--VVEIDERVtledyaedpernqtqaasieeagd 170
Cdd:COG0145    68 ALLERKGARTGLITTRGFRDVLEIGRQNRPDLYDLFIEKPEPLVPRrlRFEVRERI------------------------ 123

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  171 eaeLVKGlsgetvRILQRPQEQAIRKQLQEVYDSGLKSIAVCLMHGYTYPKHEALVGKIARE-IGFEHVSLSHELMPMIK 249
Cdd:COG0145   124 ---DADG------EVLTPLDEAEVRAAARELRAAGVEAVAVCFLHSYRNPAHERRAAEILREeLPDVPVSLSSEVSPEIR 194

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  250 LVPRATSACADAYLTPAIRKYIDGFSKGFegglgtksvkREEGSKGaRCEFMQSDGGLVDVDMFS--GLKAILSGPAGGV 327
Cdd:COG0145   195 EYERTSTTVVNAYLSPILRRYLDRLEARL----------RERGFGG-PLLIMQSNGGLASAEAAArrPVRTILSGPAGGV 263

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  328 VGYALTSydPQTKIP-VIGFDMGGTSTDVSRYGAGRYDHVFETTTAGVTIQSPQLDINTVAAGGGSRLfW--KNGLFVVG 404
Cdd:COG0145   264 VGAAALA--RAAGFDnVITFDMGGTSTDVSLIEDGEPERTTETEVAGYPVRVPMVDIHTVGAGGGSIA-WvdAGGRLRVG 340

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  405 PESASAHPGPACYRKGGP-LTITDANLFLGRLLPDFFpkIFGkneDEGLDAQASEKLFKELADQINkeiaggnkekeMSL 483
Cdd:COG0145   341 PESAGADPGPACYGRGGTePTVTDANLVLGRLDPDNF--LGG---RMPLDVEAARAAIEKLADPLG-----------LSV 404

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  484 DDIANGFIKIANETMTRPIRSLTEARGHDTSKHRLATFGGAGGQHAVAIAEALGISQILVHRYSSVLSAYGMALADVVDE 563
Cdd:COG0145   405 EEAAEGILRIANENMANAIRKVSVERGYDPRDFTLVAFGGAGPLHACALAEELGIPRVIVPPAAGVLSALGMLLADIRHD 484

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  564 RQepESKIWSDEKDVRSYLQAKMADLKSKSTATLKDQGFDEEHIHFEEYLNLRYRGTESALMIIKPTKEEAQEDYDgdew 643
Cdd:COG0145   485 YV--RSVEAPLDDADLAELNAAFAELEAEARAELAAEGVAAEDIRVERSADMRYAGQGHELTVPLPAGRLDAADLA---- 558

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  644 AFGKAFIKQHEQEFGFTLPDRDIIVDDVRARGIGKTfeglEKSVDQQLkeikPKDLQGDAKRYDTRKVFFEGGRQDTSVY 723
Cdd:COG0145   559 ALRAAFHAAHERRYGFALPDAPVEIVNLRVEAIGPV----PKPELPRL----PPGGDAAPAPKGTRPVYFDGGWVDTPVY 630

                         730       740       750
                  ....*....|....*....|....*....|..
gi 452000400  724 KLEDLEVGDRLKGPAIIADGTQTIVVTPGATA 755
Cdd:COG0145   631 DREALPPGDRIAGPAIIEEPDTTTVVPPGWRA 662
HyuB COG0146
N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit [Amino acid transport ...
 778-1323 0e+00

N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit [Amino acid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 439916  Cd Length: 563  Bit Score: 614.84  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  778 TKEVDPILLSIFAHRFMAIAEQMGRALQKTSVSTNVKERLDYSCALFDADGGLVANAPHLPVHLGSMSTCVRK-QAAIWK 856
Cdd:COG0146     2 GTTVDPVTLEVIRNRLIAIAEEMGETLQRTAFSPNIKERLDFSCALFDADGRLVAQAPGIPVHLGSMPEAVKAvIERFGN 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  857 GKLKKGDVLVSNHPMFGGTHLPDITVITPAFSGDNIVFYVASRAHHADIGGILPGSMPPASKELYQEGAAIKSEKLVSEG 936
Cdd:COG0146    82 DGIRPGDVFITNDPYLGGTHLPDITVVTPVFHDGELVGFVASRAHHADIGGIVPGSMPPDATEIFQEGLRIPPVKLVEAG 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400  937 HFNEERITELLldepgqypgcSGTRCLSDNINDLKAQVAANQKGINLISTLMSDYGEEVVKFYMTNIQANAEKSVRALLK 1016
Cdd:COG0146   162 ELNEDVLRLIL----------ANVRTPDQNLGDLRAQIAANRVGERRLLELVERYGLDTVEAAMDELLDYAERAVRAAIA 231

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400 1017 D----VYkrfegqdlSAEEFMDDGS----PIRLKVSIDPEKGEAVFDFSGTGPEVYGNINAPEAVTYSAIIYCLRCLISE 1088
Cdd:COG0146   232 AlpdgTY--------RAEDFLDDDGvgdePIKIKVTVTVKGDRITVDFTGTSPQVPGNINAPLAVTRAAVLYALRCLLDP 303

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400 1089 DIPLNQGCLKPIHVLIPKKSFLSPSDNAAVVGGNVLTSQRVTDVVLKAF------RACAASQGDCNNLTFgfggttfgeg 1162
Cdd:COG0146   304 DIPLNAGCLRPIEVIAPEGSILNPRYPAAVVAGNVETSQRVVDAVFGALaqalpeRVPAASQGTMNNLTF---------- 373

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400 1163 akSGERKETKGFGYYETIAGGSGAGPTWNGTSGVHTHMTNTRITDSEVFERRYPVLLREFSLRQGSAGRGMHIGGEGVIR 1242
Cdd:COG0146   374 --GGVDPRGEPFVYYETIGGGSGARPGGDGLDAVHTHMTNTRNTPVEVLEARYPVLVERYELRPDSGGAGKYRGGLGVVR 451

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400 1243 DIEFRIP-VQVSILSERRVYHPYGMEGGGDAACGLNIWVRKTLEKKDaardrkedveyryinLGAKNTASMRPGERIIIH 1321
Cdd:COG0146   452 EIRFLEPeMTVSLLGDRRRFPPWGLAGGGPGAPGRNVLVRGDGDEEE---------------LGGKATVPLQPGDVVVIE 516


                  ..
gi 452000400 1322 TP 1323
Cdd:COG0146   517 TP 518
Hydantoinase_A pfam01968
Hydantoinase/oxoprolinase; This family includes the enzymes hydantoinase and oxoprolinase EC:3. ...
 253-564 1.92e-113

Hydantoinase/oxoprolinase; This family includes the enzymes hydantoinase and oxoprolinase EC:3.5.2.9. Both reactions involve the hydrolysis of 5-membered rings via hydrolysis of their internal imide bonds.


Pssm-ID: 396517 [Multi-domain]  Cd Length: 288  Bit Score: 357.75  E-value: 1.92e-113
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400   253 RATSACADAYLTPAIRKYIDGFSKGFEgglgtksvkrEEGSKgARCEFMQSDGGLVDVDMFSG--LKAILSGPAGGVVGY 330
Cdd:pfam01968    1 RTVTAVVNAYLAPIMREYLEGVEDSLE----------KVGSK-APVYVMQSDGGLVSIDEARKrpVETILSGPAAGVVGA 69

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400   331 ALTSyDPQTKIPVIGFDMGGTSTDVSRYGAGRYDHVFETTTAGVTIQSPQLDINTVAAGGGSRL-FWKNGLFVVGPESAS 409
Cdd:pfam01968   70 AYTG-KLLGNKNLIGFDMGGTSTDISPIIDGEPEITTETEVAGYPTRLPRLDINTVGAGGGSILvSFLGGKVRVGPESAG 148

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400   410 AHPGPACYRKGG-PLTITDANLFLGRLLPDFFPKIFGKnedegLDAQASEKLFKELADQINkeiaggnkekeMSLDDIAN 488
Cdd:pfam01968  149 ADPGPACYRKGGtFPTVTDANLVLGRLNPEDFLGGDGK-----LDVEAARRAFEKLADPLN-----------LGVEEVAE 212

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 452000400   489 GFIKIANETMTRPIRSLTEARGHDTSKHRLATFGGAGGQHAVAIAEALGISQILVHRYSSVLSAYGMALADVVDER 564
Cdd:pfam01968  213 GIIRIANETMARAVRLVTVERGYDPSEFVLVVFGGAGPQHAPALAEELGIKKVIVPPYPGVLSAYGMALADLRAER 288
Hydant_A_N pfam05378
Hydantoinase/oxoprolinase N-terminal region; This family is found at the N-terminus of the ...
 12-234 1.85e-59

Hydantoinase/oxoprolinase N-terminal region; This family is found at the N-terminus of the pfam01968 family.


Pssm-ID: 398834 [Multi-domain]  Cd Length: 176  Bit Score: 202.13  E-value: 1.85e-59
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400    12 RIAIDRGGTFTDCVGNpgTGKMEDDVLIKLLSVDpsnydDAPLEGIRRLLSRFTGTEIPRgqpldTSKIESIRMGTTVAT 91
Cdd:pfam05378    1 RIGIDVGGTFTDAVAL--DEGDGEVAVIKVLTTP-----DDPVEGIREALEELLGELGPR-----TGKVDTVRHGTTVAT 68

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400    92 NALLERKGEDIAMVVTKGFKDCLEIGNQSRPNIFalDIRKPEVLYKKVVEIDERVTLEdyaedpernqtqaasieeagde 171
Cdd:pfam05378   69 NALLERKGARVGLITTKGFRDLLEIGRQNRPDLF--DLYKPLVLYELVVEVDERVDAD---------------------- 124

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 452000400   172 aelvkglsgetVRILQRPQEQAIRKQLQEVYDSGLKSIAVCLMHGYTYPKHEALVGKIAREIG 234
Cdd:pfam05378  125 -----------GEVLKPLDEEEVREALKALKDAGVEAIAVVLLHSYLNPEHELRVAEIAREEG 176
Hydant_A_C pfam19278
Hydantoinase/oxoprolinase C-terminal domain; This domain is found at the C-terminus of ...
 582-752 1.42e-10

Hydantoinase/oxoprolinase C-terminal domain; This domain is found at the C-terminus of acetophenone carboxylase alpha subunit. According to ECOD this domain adopts a reverse ferredoxin fold. This domain is found at the C-terminus of a wide range of related enzymes subunits.


Pssm-ID: 437110 [Multi-domain]  Cd Length: 193  Bit Score: 61.85  E-value: 1.42e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400   582 LQAKMADLKSKSTATLKDQGFDEEHIHFEEYLNLRYRGTESALMIIKP-TKEEAQEDYDGDEWAFGKAFIKQHEQ----- 655
Cdd:pfam19278   14 LQAAWSELADKVIEEFVINGYDPEDVTLRPGYRMQYMGQLNDLEIESPiASAETAEDWDRLVEAFEETYARVYAKaarsp 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452000400   656 EFGFTLpdrdiivddvrargigkTFEGLEKSVDQQLKEIKPKDLQG----DAKRYDTRKVFFEGGRQDTSVYKLEDLEVG 731
Cdd:pfam19278   94 ELGYSV-----------------TGAIMRGVVDKPKPVIPEEPLAGetppPEARLGTRPFYRKGKWVEAQLWEMEKLKPG 156

                          170       180
                   ....*....|....*....|.
gi 452000400   732 DRLKGPAIIADGTQTIVVTPG 752
Cdd:pfam19278  157 NRITGPAIIESPATTFVVPPG 177
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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