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Conserved domains on  [gi|476223761|gb|EMW43502|]
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RHS repeat-associated core domain protein [Escherichia coli 2788150]

Protein Classification

RHS repeat domain-containing protein( domain architecture ID 12063925)

RHS (Rearrangement hotspot) repeat domain-containing protein comprises multiple tandem 21-residue repeats, the YD-peptide repeats, and is distantly related to the wall-associated protein A (WapA) and may mediate intercellular competition

Gene Ontology:  GO:0030246
PubMed:  23572593|7868617

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RHS_core super family cl49306
RHS element core protein;
1-958 0e+00

RHS element core protein;


The actual alignment was detected with superfamily member NF041261:

Pssm-ID: 469161 [Multi-domain]  Cd Length: 1261  Bit Score: 1992.56  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761    1 MHDPAYPESLPGAPLARYTYTEAGELLAVYDRSNTQVRAFTYDAQHPGRMVAHRYAGRPEMRYRYDDTGRVVEQLNPAGL 80
Cdd:NF041261  305 THDPAYPESLPAAPLVRYTYTEAGELLAVYDRSNTQVRAFTYDAQHPGRMVAHRYAGRPEMCYRYDDTGRVTEQLNPAGL 384

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761   81 SYRYQYEQDRITVTDSLNRREVLHTEGGAGLKRVVKKELADGSVTHSGYDAAGRLTAQTDAAGRRTEYGLNVVSGDITDI 160
Cdd:NF041261  385 SYRYQYEQDRITITDSLNRREVLHTEGEGGLKRVVKKEHADGSVTRSGYDAAGRLTAQTDAAGRRTEYSLNVVSGDITDI 464

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  161 TTPDGRETKFYYNDGNQLTAVVSPDGLESRRAYDEPGRLVSETSRSGDVIRYAYDNPHSELPATTTDATGSTRQMTWSRY 240
Cdd:NF041261  465 TTPDGRETKFYYNDGNQLTSVTSPDGLESRREYDEPGRLVSETSRSGETTRYRYDDPHSELPATTTDATGSTKQMTWSRY 544

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  241 GQLLAFTDCSGYQTRYEYDRFGQMTAVHREEGISLYRRYDNRGRLTSVKDAQGRETRYEYNAAGDLTAVITPDGNRSETQ 320
Cdd:NF041261  545 GQLLAFTDCSGYQTRYEYDRFGQMTAVHREEGISTYRRYDNRGQLTSVKDAQGRETRYEYNAAGDLTAVITPDGNRSETQ 624

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  321 YDAWGKAVSTTQGGLTRSMEYDAAGRVISLTNENGSHSVFSYDALDRLVQQGGFDGRTQRYHYDLTGKLTQSEDEGLVTL 400
Cdd:NF041261  625 YDAWGKAVSTTQGGLTRSMEYDAAGRITTLTNENGSHSTFLYDALDRLVQQRGFDGRTQRYHYDLTGKLTQSEDEGLVTL 704

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  401 WYYDESDRITHRTVNGEPAEQWQYDDHGWLTDISHLSEGHRVAVHYGYDDKGRLTGERQTVENPETGELLWQHETTHAYN 480
Cdd:NF041261  705 WHYDESDRITHRTVNGEPAEQWQYDEHGWLTDISHLSEGHRVAVHYGYDDKGRLTGERQTVENPETGELLWQHETGHAYN 784

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  481 EQGLANRVTPDSLPPVEWLTYGSGYLAGMKLGDTPLLEYTRDRMHRETVRSFGsMAGSNAAYKLTSTYTPAGQLQSQHLN 560
Cdd:NF041261  785 EQGLANRVTPDSLPPVEWLTYGSGYLAGMKLGGTPLVEYTRDRLHRETVRSFG-GAGSNAAYELTTAYTPAGQLQSQHLN 863

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  561 SLVYDRDYGWNDNGDLVRISGPRQTREYGYSATGRLESVRTLAPDLDIRIPYATDPAGNRLPDPELHPDSTLTAWPDNRI 640
Cdd:NF041261  864 SLVYDRDYTWNDNGDLVRISGPRQTREYGYSATGRLTGVHTTAANLDIRIPYATDPAGNRLPDPELHPDSTLTAWPDNRI 943

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  641 AEDAHYVYHYDEYGRLTEKTDLIPAGVIRTDDERTHHYHYDSQHRLVFYTRIQHGEPLVESRYLYDPLGRRMAKRVWRRE 720
Cdd:NF041261  944 AEDAHYVYRYDEYGRLTEKTDRIPEGVIRTDDERTHHYHYDSQHRLVFYTRIQHGEPLVESRYLYDPLGRRMAKRVWRRE 1023

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  721 RDLTGWMSLSRKPEMTWYGWDGDRLTTVQTDTTRIQTVYQPGSFAPLIRIETDNGEREKAQRRSLAEKLQQEGSEDGHGV 800
Cdd:NF041261 1024 RDLTGWMSLSRKPEVTWYGWDGDRLTTVQTDTTRIQTVYQPGSFTPLIRVETENGERAKAQRRSLAETLQQEGSENGHGV 1103

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  801 VFPAELVRLLDRLEEEIRADRVSSESRAWLAQCGLTVEQLARQVEPEYTPARKVHFYHCDHRGLPLALISEDGNTAWRGE 880
Cdd:NF041261 1104 VFPAELVRMLDRLEEEIRADRVSEESRAWLAQCGLTVEQMARQVEPEYTPARKLHLYHCDHRGLPLALISEEGNTAWQGE 1183

                         890       900       910       920       930       940       950
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 476223761  881 YDEWGNQLNEENPYSLPQPYRLPGQQHDEESGLYYNRNRYYDPLQGRYITQDPIGLAGGWNLYNYPLNPIIRMDPLGL 958
Cdd:NF041261 1184 YDEWGNLLNEENPHHLQQPYRLPGQQYDEESGLYYNRNRYYDPLQGRYITQDPIGLKGGWNLYQYPLNPIRFIDPLGL 1261
 
Name Accession Description Interval E-value
RHS_core NF041261
RHS element core protein;
1-958 0e+00

RHS element core protein;


Pssm-ID: 469161 [Multi-domain]  Cd Length: 1261  Bit Score: 1992.56  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761    1 MHDPAYPESLPGAPLARYTYTEAGELLAVYDRSNTQVRAFTYDAQHPGRMVAHRYAGRPEMRYRYDDTGRVVEQLNPAGL 80
Cdd:NF041261  305 THDPAYPESLPAAPLVRYTYTEAGELLAVYDRSNTQVRAFTYDAQHPGRMVAHRYAGRPEMCYRYDDTGRVTEQLNPAGL 384

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761   81 SYRYQYEQDRITVTDSLNRREVLHTEGGAGLKRVVKKELADGSVTHSGYDAAGRLTAQTDAAGRRTEYGLNVVSGDITDI 160
Cdd:NF041261  385 SYRYQYEQDRITITDSLNRREVLHTEGEGGLKRVVKKEHADGSVTRSGYDAAGRLTAQTDAAGRRTEYSLNVVSGDITDI 464

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  161 TTPDGRETKFYYNDGNQLTAVVSPDGLESRRAYDEPGRLVSETSRSGDVIRYAYDNPHSELPATTTDATGSTRQMTWSRY 240
Cdd:NF041261  465 TTPDGRETKFYYNDGNQLTSVTSPDGLESRREYDEPGRLVSETSRSGETTRYRYDDPHSELPATTTDATGSTKQMTWSRY 544

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  241 GQLLAFTDCSGYQTRYEYDRFGQMTAVHREEGISLYRRYDNRGRLTSVKDAQGRETRYEYNAAGDLTAVITPDGNRSETQ 320
Cdd:NF041261  545 GQLLAFTDCSGYQTRYEYDRFGQMTAVHREEGISTYRRYDNRGQLTSVKDAQGRETRYEYNAAGDLTAVITPDGNRSETQ 624

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  321 YDAWGKAVSTTQGGLTRSMEYDAAGRVISLTNENGSHSVFSYDALDRLVQQGGFDGRTQRYHYDLTGKLTQSEDEGLVTL 400
Cdd:NF041261  625 YDAWGKAVSTTQGGLTRSMEYDAAGRITTLTNENGSHSTFLYDALDRLVQQRGFDGRTQRYHYDLTGKLTQSEDEGLVTL 704

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  401 WYYDESDRITHRTVNGEPAEQWQYDDHGWLTDISHLSEGHRVAVHYGYDDKGRLTGERQTVENPETGELLWQHETTHAYN 480
Cdd:NF041261  705 WHYDESDRITHRTVNGEPAEQWQYDEHGWLTDISHLSEGHRVAVHYGYDDKGRLTGERQTVENPETGELLWQHETGHAYN 784

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  481 EQGLANRVTPDSLPPVEWLTYGSGYLAGMKLGDTPLLEYTRDRMHRETVRSFGsMAGSNAAYKLTSTYTPAGQLQSQHLN 560
Cdd:NF041261  785 EQGLANRVTPDSLPPVEWLTYGSGYLAGMKLGGTPLVEYTRDRLHRETVRSFG-GAGSNAAYELTTAYTPAGQLQSQHLN 863

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  561 SLVYDRDYGWNDNGDLVRISGPRQTREYGYSATGRLESVRTLAPDLDIRIPYATDPAGNRLPDPELHPDSTLTAWPDNRI 640
Cdd:NF041261  864 SLVYDRDYTWNDNGDLVRISGPRQTREYGYSATGRLTGVHTTAANLDIRIPYATDPAGNRLPDPELHPDSTLTAWPDNRI 943

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  641 AEDAHYVYHYDEYGRLTEKTDLIPAGVIRTDDERTHHYHYDSQHRLVFYTRIQHGEPLVESRYLYDPLGRRMAKRVWRRE 720
Cdd:NF041261  944 AEDAHYVYRYDEYGRLTEKTDRIPEGVIRTDDERTHHYHYDSQHRLVFYTRIQHGEPLVESRYLYDPLGRRMAKRVWRRE 1023

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  721 RDLTGWMSLSRKPEMTWYGWDGDRLTTVQTDTTRIQTVYQPGSFAPLIRIETDNGEREKAQRRSLAEKLQQEGSEDGHGV 800
Cdd:NF041261 1024 RDLTGWMSLSRKPEVTWYGWDGDRLTTVQTDTTRIQTVYQPGSFTPLIRVETENGERAKAQRRSLAETLQQEGSENGHGV 1103

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  801 VFPAELVRLLDRLEEEIRADRVSSESRAWLAQCGLTVEQLARQVEPEYTPARKVHFYHCDHRGLPLALISEDGNTAWRGE 880
Cdd:NF041261 1104 VFPAELVRMLDRLEEEIRADRVSEESRAWLAQCGLTVEQMARQVEPEYTPARKLHLYHCDHRGLPLALISEEGNTAWQGE 1183

                         890       900       910       920       930       940       950
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 476223761  881 YDEWGNQLNEENPYSLPQPYRLPGQQHDEESGLYYNRNRYYDPLQGRYITQDPIGLAGGWNLYNYPLNPIIRMDPLGL 958
Cdd:NF041261 1184 YDEWGNLLNEENPHHLQQPYRLPGQQYDEESGLYYNRNRYYDPLQGRYITQDPIGLKGGWNLYQYPLNPIRFIDPLGL 1261
Rhs_assc_core TIGR03696
RHS repeat-associated core domain; This model represents a conserved unique core sequence ...
 881-958 4.49e-29

RHS repeat-associated core domain; This model represents a conserved unique core sequence shared by large numbers of proteins. It is occasional in the Archaea Methanosarcina barkeri) but common in bacteria and eukaryotes. Most fall into two large classes. One class consists of long proteins in which two classes of repeats are abundant: an FG-GAP repeat (pfam01839) class, and an RHS repeat (pfam05593) or YD repeat (TIGR01643). This class includes secreted bacterial insecticidal toxins and intercellular signalling proteins such as the teneurins in animals. The other class consists of uncharacterized proteins shorter than 400 amino acids, where this core domain of about 75 amino acids tends to occur in the N-terminal half. Over twenty such proteins are found in Pseudomonas putida alone; little sequence similarity or repeat structure is found among these proteins outside the region modeled by this domain.


Pssm-ID: 274730 [Multi-domain]  Cd Length: 77  Bit Score: 111.05  E-value: 4.49e-29
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 476223761   881 YDEWGNQLNEENpySLPQPYRLPGQQHDEESGLYYNRNRYYDPLQGRYITQDPIGLAGGWNLYNY-PLNPIIRMDPLGL 958
Cdd:TIGR03696    1 YDPYGEVLSESG--AAPNPLRFTGQYYDAETGLYYNGARYYDPELGRFLSPDPIGLGGGLNLYAYvGNNPVNWVDPLGL 77
RhsA COG3209
Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction ...
 2-1005 4.81e-24

Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only];


Pssm-ID: 442442 [Multi-domain]  Cd Length: 1103  Bit Score: 109.85  E-value: 4.81e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761    2 HDPAYPESLPGAPLARYTYTEAGELLAVYDRSNTQVRAFTYDAQHPGRMVAHRYAGRPEMRYRYDDTGRVVEQLNPAGLS 81
Cdd:COG3209   193 TGLAGSALLALGSGAILGGLAGAYSGSATTATGTALGTPASVAATVTGSATGAAGAGAAVATAATTLGGTTGAGTGASGA 272

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761   82 YRYQYEQDRITVTDSLNRREVLHTEGGAGLKRVVKKELADGSVTHSGYDAAGRLTAQTDAAGRRTEYGLNVVSGDITDIT 161
Cdd:COG3209   273 GLDASTGTGGAGGSNAAATAGGLGGAGLGSGGAGGGGTAGGTTTAAGTTGTAAVSGAADAGTTTTTGTGTGGTTTTVGGG 352

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  162 TPDGRETKFYYNDGNQLTAVVSPDGLESRRAYDEPGRLVSETSRSGDVIRYAYDNPHSELPATTTDATGSTRQMTWSRYG 241
Cdd:COG3209   353 GSLTLGGYGAAGGLTTSVGAGGGGSTSGSTTTVGGGGTATGSGGGSSTTGVGAGTTTTSTTGGDGGPATAAGALTAGGTA 432

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  242 QLLAFTDCSGYQTRYEYDRFGQMTAVHREEGISLYRRYDNRGRLTSVKDAQGRET-RYEYNAAGDLTAVITPDGNRSETQ 320
Cdd:COG3209   433 TGTGTGGGGTTAGTDATTTTGGAGASGTLTTTGGAATGATTGGGTEAGTGGGTLTsGSAGATTLGTDTTLDDTLGGTTTT 512

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  321 YDAWGKAVSTTQGGLTRSMEYDAAGRVISLTNENGSHSVFSYDALDRLVQQGGFDGRTQRYHYDLTGKLTQSEDEGLVTL 400
Cdd:COG3209   513 TAGARGLVVTTGTTLTLGTTTTATLSATDATGTGDTTTTGTVGTGTSTGTGGTGTVTTTGDGTGGASTTTGTTGGTATTT 592

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  401 WYYDESDRITHRTVNGEPAEQWQYDDHGWLTDISHLSEGHRVAVHYGYDDKGRLTGERQTVENPETGELLWQHETTHAYN 480
Cdd:COG3209   593 TVTTTTTTSTAGTTTTTTSGYTRAGLTLTLGTGTASGLERATASTGSTTGGTTGTGVTTTGTTTTRATGTTGTGTGVTAG 672

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  481 EQGLANRVTPDSLPPVEWLTYGSGYLAGMKLGDTPLLEYTRDRMHRETVRSFGSMAGSNAAYKLTSTYTPAGQLQSQHLN 560
Cdd:COG3209   673 LTTLATGGTTVGGGTGTTSTATTGATTGGTETGTTVTTLAGGTTTRLGTTTTGGGGGTTTDGTGTGGTTGTLTTTSTTTT 752

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  561 SLVYDRDYGWNDNGDLVRISGPRQ------TREYGYSATGRLESVRTLApdlDIRIPYATDPAGNRlpdpelhpdSTLTA 634
Cdd:COG3209   753 TTAGALTYTYDALGRLTSETTPGGvtqgtyTTRYTYDALGRLTSVTYPD---GETVTYTYDALGRL---------TSVIT 820

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  635 WPDNRIAEDAHYVYHYDEYGRLTEKTDLIPAGvirtddERTHHYHYDSQHRLvfytrIQHGEPLVESRYLYDPLGRRMAK 714
Cdd:COG3209   821 VGSGGGTDLQDRTYTYDAAGNITSITDALRAG------TLTQTYTYDALGRL-----TSATDPGTTESYTYDANGNLTSR 889

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  715 RVWRRerdltgwmslsrkpemTWYGWDG-DRLTTVQT-DTTRIQTVYqpgsfaplirietdngerekaqrrslaeklqqe 792
Cdd:COG3209   890 TDGGT----------------TTYTYDAlGRLVSVTKpDGTTTTYTY--------------------------------- 920

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  793 gseDGHGvvfpaelvrlldrleeeiradrvssesrawlaqcgltveqlarqvepeytparkvhfyHCDHRGLPLALISED 872
Cdd:COG3209   921 ---DALG----------------------------------------------------------HTDHLGSVRALTDAS 939

                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  873 GNTAWRGEYDEWGNQLnEENPYSLPQPYRLPGQQHDEESGLYYNRNRYYDPLQGRYITQDPIGLAGGWNLYNYPL-NPII 951
Cdd:COG3209   940 GQVVWRYDYDPFGNLL-AETSGAAANPLRFTGQEYDAETGLYYNGARYYDPALGRFLSPDPIGLAGGLNLYAYVGnNPVN 1018

                         970       980       990      1000      1010
                  ....*....|....*....|....*....|....*....|....*....|....
gi 476223761  952 RMDPLGLYNLYQLLYDVWHDDSYGTSSIDITGSGDLISLGGHAGLGVAFAKKKG 1005
Cdd:COG3209  1019 YVDPLGLAALLGTTGLGGGAGVGAGAAGGGAAAAGGSAGAGAAGGGAGGAGAGG 1072
RHS pfam03527
RHS protein;
854-891 7.88e-13

RHS protein;


Pssm-ID: 427349 [Multi-domain]  Cd Length: 38  Bit Score: 63.48  E-value: 7.88e-13
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 476223761   854 VHFYHCDHRGLPLALISEDGNTAWRGEYDEWGNQLNEE 891
Cdd:pfam03527    1 IYYYHTDHLGTPEELTDEAGEIVWSAEYDAWGNVTEER 38
 
Name Accession Description Interval E-value
RHS_core NF041261
RHS element core protein;
1-958 0e+00

RHS element core protein;


Pssm-ID: 469161 [Multi-domain]  Cd Length: 1261  Bit Score: 1992.56  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761    1 MHDPAYPESLPGAPLARYTYTEAGELLAVYDRSNTQVRAFTYDAQHPGRMVAHRYAGRPEMRYRYDDTGRVVEQLNPAGL 80
Cdd:NF041261  305 THDPAYPESLPAAPLVRYTYTEAGELLAVYDRSNTQVRAFTYDAQHPGRMVAHRYAGRPEMCYRYDDTGRVTEQLNPAGL 384

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761   81 SYRYQYEQDRITVTDSLNRREVLHTEGGAGLKRVVKKELADGSVTHSGYDAAGRLTAQTDAAGRRTEYGLNVVSGDITDI 160
Cdd:NF041261  385 SYRYQYEQDRITITDSLNRREVLHTEGEGGLKRVVKKEHADGSVTRSGYDAAGRLTAQTDAAGRRTEYSLNVVSGDITDI 464

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  161 TTPDGRETKFYYNDGNQLTAVVSPDGLESRRAYDEPGRLVSETSRSGDVIRYAYDNPHSELPATTTDATGSTRQMTWSRY 240
Cdd:NF041261  465 TTPDGRETKFYYNDGNQLTSVTSPDGLESRREYDEPGRLVSETSRSGETTRYRYDDPHSELPATTTDATGSTKQMTWSRY 544

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  241 GQLLAFTDCSGYQTRYEYDRFGQMTAVHREEGISLYRRYDNRGRLTSVKDAQGRETRYEYNAAGDLTAVITPDGNRSETQ 320
Cdd:NF041261  545 GQLLAFTDCSGYQTRYEYDRFGQMTAVHREEGISTYRRYDNRGQLTSVKDAQGRETRYEYNAAGDLTAVITPDGNRSETQ 624

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  321 YDAWGKAVSTTQGGLTRSMEYDAAGRVISLTNENGSHSVFSYDALDRLVQQGGFDGRTQRYHYDLTGKLTQSEDEGLVTL 400
Cdd:NF041261  625 YDAWGKAVSTTQGGLTRSMEYDAAGRITTLTNENGSHSTFLYDALDRLVQQRGFDGRTQRYHYDLTGKLTQSEDEGLVTL 704

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  401 WYYDESDRITHRTVNGEPAEQWQYDDHGWLTDISHLSEGHRVAVHYGYDDKGRLTGERQTVENPETGELLWQHETTHAYN 480
Cdd:NF041261  705 WHYDESDRITHRTVNGEPAEQWQYDEHGWLTDISHLSEGHRVAVHYGYDDKGRLTGERQTVENPETGELLWQHETGHAYN 784

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  481 EQGLANRVTPDSLPPVEWLTYGSGYLAGMKLGDTPLLEYTRDRMHRETVRSFGsMAGSNAAYKLTSTYTPAGQLQSQHLN 560
Cdd:NF041261  785 EQGLANRVTPDSLPPVEWLTYGSGYLAGMKLGGTPLVEYTRDRLHRETVRSFG-GAGSNAAYELTTAYTPAGQLQSQHLN 863

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  561 SLVYDRDYGWNDNGDLVRISGPRQTREYGYSATGRLESVRTLAPDLDIRIPYATDPAGNRLPDPELHPDSTLTAWPDNRI 640
Cdd:NF041261  864 SLVYDRDYTWNDNGDLVRISGPRQTREYGYSATGRLTGVHTTAANLDIRIPYATDPAGNRLPDPELHPDSTLTAWPDNRI 943

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  641 AEDAHYVYHYDEYGRLTEKTDLIPAGVIRTDDERTHHYHYDSQHRLVFYTRIQHGEPLVESRYLYDPLGRRMAKRVWRRE 720
Cdd:NF041261  944 AEDAHYVYRYDEYGRLTEKTDRIPEGVIRTDDERTHHYHYDSQHRLVFYTRIQHGEPLVESRYLYDPLGRRMAKRVWRRE 1023

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  721 RDLTGWMSLSRKPEMTWYGWDGDRLTTVQTDTTRIQTVYQPGSFAPLIRIETDNGEREKAQRRSLAEKLQQEGSEDGHGV 800
Cdd:NF041261 1024 RDLTGWMSLSRKPEVTWYGWDGDRLTTVQTDTTRIQTVYQPGSFTPLIRVETENGERAKAQRRSLAETLQQEGSENGHGV 1103

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  801 VFPAELVRLLDRLEEEIRADRVSSESRAWLAQCGLTVEQLARQVEPEYTPARKVHFYHCDHRGLPLALISEDGNTAWRGE 880
Cdd:NF041261 1104 VFPAELVRMLDRLEEEIRADRVSEESRAWLAQCGLTVEQMARQVEPEYTPARKLHLYHCDHRGLPLALISEEGNTAWQGE 1183

                         890       900       910       920       930       940       950
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 476223761  881 YDEWGNQLNEENPYSLPQPYRLPGQQHDEESGLYYNRNRYYDPLQGRYITQDPIGLAGGWNLYNYPLNPIIRMDPLGL 958
Cdd:NF041261 1184 YDEWGNLLNEENPHHLQQPYRLPGQQYDEESGLYYNRNRYYDPLQGRYITQDPIGLKGGWNLYQYPLNPIRFIDPLGL 1261
Rhs_assc_core TIGR03696
RHS repeat-associated core domain; This model represents a conserved unique core sequence ...
 881-958 4.49e-29

RHS repeat-associated core domain; This model represents a conserved unique core sequence shared by large numbers of proteins. It is occasional in the Archaea Methanosarcina barkeri) but common in bacteria and eukaryotes. Most fall into two large classes. One class consists of long proteins in which two classes of repeats are abundant: an FG-GAP repeat (pfam01839) class, and an RHS repeat (pfam05593) or YD repeat (TIGR01643). This class includes secreted bacterial insecticidal toxins and intercellular signalling proteins such as the teneurins in animals. The other class consists of uncharacterized proteins shorter than 400 amino acids, where this core domain of about 75 amino acids tends to occur in the N-terminal half. Over twenty such proteins are found in Pseudomonas putida alone; little sequence similarity or repeat structure is found among these proteins outside the region modeled by this domain.


Pssm-ID: 274730 [Multi-domain]  Cd Length: 77  Bit Score: 111.05  E-value: 4.49e-29
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 476223761   881 YDEWGNQLNEENpySLPQPYRLPGQQHDEESGLYYNRNRYYDPLQGRYITQDPIGLAGGWNLYNY-PLNPIIRMDPLGL 958
Cdd:TIGR03696    1 YDPYGEVLSESG--AAPNPLRFTGQYYDAETGLYYNGARYYDPELGRFLSPDPIGLGGGLNLYAYvGNNPVNWVDPLGL 77
RhsA COG3209
Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction ...
 2-1005 4.81e-24

Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only];


Pssm-ID: 442442 [Multi-domain]  Cd Length: 1103  Bit Score: 109.85  E-value: 4.81e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761    2 HDPAYPESLPGAPLARYTYTEAGELLAVYDRSNTQVRAFTYDAQHPGRMVAHRYAGRPEMRYRYDDTGRVVEQLNPAGLS 81
Cdd:COG3209   193 TGLAGSALLALGSGAILGGLAGAYSGSATTATGTALGTPASVAATVTGSATGAAGAGAAVATAATTLGGTTGAGTGASGA 272

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761   82 YRYQYEQDRITVTDSLNRREVLHTEGGAGLKRVVKKELADGSVTHSGYDAAGRLTAQTDAAGRRTEYGLNVVSGDITDIT 161
Cdd:COG3209   273 GLDASTGTGGAGGSNAAATAGGLGGAGLGSGGAGGGGTAGGTTTAAGTTGTAAVSGAADAGTTTTTGTGTGGTTTTVGGG 352

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  162 TPDGRETKFYYNDGNQLTAVVSPDGLESRRAYDEPGRLVSETSRSGDVIRYAYDNPHSELPATTTDATGSTRQMTWSRYG 241
Cdd:COG3209   353 GSLTLGGYGAAGGLTTSVGAGGGGSTSGSTTTVGGGGTATGSGGGSSTTGVGAGTTTTSTTGGDGGPATAAGALTAGGTA 432

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  242 QLLAFTDCSGYQTRYEYDRFGQMTAVHREEGISLYRRYDNRGRLTSVKDAQGRET-RYEYNAAGDLTAVITPDGNRSETQ 320
Cdd:COG3209   433 TGTGTGGGGTTAGTDATTTTGGAGASGTLTTTGGAATGATTGGGTEAGTGGGTLTsGSAGATTLGTDTTLDDTLGGTTTT 512

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  321 YDAWGKAVSTTQGGLTRSMEYDAAGRVISLTNENGSHSVFSYDALDRLVQQGGFDGRTQRYHYDLTGKLTQSEDEGLVTL 400
Cdd:COG3209   513 TAGARGLVVTTGTTLTLGTTTTATLSATDATGTGDTTTTGTVGTGTSTGTGGTGTVTTTGDGTGGASTTTGTTGGTATTT 592

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  401 WYYDESDRITHRTVNGEPAEQWQYDDHGWLTDISHLSEGHRVAVHYGYDDKGRLTGERQTVENPETGELLWQHETTHAYN 480
Cdd:COG3209   593 TVTTTTTTSTAGTTTTTTSGYTRAGLTLTLGTGTASGLERATASTGSTTGGTTGTGVTTTGTTTTRATGTTGTGTGVTAG 672

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  481 EQGLANRVTPDSLPPVEWLTYGSGYLAGMKLGDTPLLEYTRDRMHRETVRSFGSMAGSNAAYKLTSTYTPAGQLQSQHLN 560
Cdd:COG3209   673 LTTLATGGTTVGGGTGTTSTATTGATTGGTETGTTVTTLAGGTTTRLGTTTTGGGGGTTTDGTGTGGTTGTLTTTSTTTT 752

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  561 SLVYDRDYGWNDNGDLVRISGPRQ------TREYGYSATGRLESVRTLApdlDIRIPYATDPAGNRlpdpelhpdSTLTA 634
Cdd:COG3209   753 TTAGALTYTYDALGRLTSETTPGGvtqgtyTTRYTYDALGRLTSVTYPD---GETVTYTYDALGRL---------TSVIT 820

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  635 WPDNRIAEDAHYVYHYDEYGRLTEKTDLIPAGvirtddERTHHYHYDSQHRLvfytrIQHGEPLVESRYLYDPLGRRMAK 714
Cdd:COG3209   821 VGSGGGTDLQDRTYTYDAAGNITSITDALRAG------TLTQTYTYDALGRL-----TSATDPGTTESYTYDANGNLTSR 889

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  715 RVWRRerdltgwmslsrkpemTWYGWDG-DRLTTVQT-DTTRIQTVYqpgsfaplirietdngerekaqrrslaeklqqe 792
Cdd:COG3209   890 TDGGT----------------TTYTYDAlGRLVSVTKpDGTTTTYTY--------------------------------- 920

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  793 gseDGHGvvfpaelvrlldrleeeiradrvssesrawlaqcgltveqlarqvepeytparkvhfyHCDHRGLPLALISED 872
Cdd:COG3209   921 ---DALG----------------------------------------------------------HTDHLGSVRALTDAS 939

                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  873 GNTAWRGEYDEWGNQLnEENPYSLPQPYRLPGQQHDEESGLYYNRNRYYDPLQGRYITQDPIGLAGGWNLYNYPL-NPII 951
Cdd:COG3209   940 GQVVWRYDYDPFGNLL-AETSGAAANPLRFTGQEYDAETGLYYNGARYYDPALGRFLSPDPIGLAGGLNLYAYVGnNPVN 1018

                         970       980       990      1000      1010
                  ....*....|....*....|....*....|....*....|....*....|....
gi 476223761  952 RMDPLGLYNLYQLLYDVWHDDSYGTSSIDITGSGDLISLGGHAGLGVAFAKKKG 1005
Cdd:COG3209  1019 YVDPLGLAALLGTTGLGGGAGVGAGAAGGGAAAAGGSAGAGAAGGGAGGAGAGG 1072
RHS pfam03527
RHS protein;
854-891 7.88e-13

RHS protein;


Pssm-ID: 427349 [Multi-domain]  Cd Length: 38  Bit Score: 63.48  E-value: 7.88e-13
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 476223761   854 VHFYHCDHRGLPLALISEDGNTAWRGEYDEWGNQLNEE 891
Cdd:pfam03527    1 IYYYHTDHLGTPEELTDEAGEIVWSAEYDAWGNVTEER 38
RHS_repeat pfam05593
RHS Repeat; RHS proteins contain extended repeat regions. These repeats often appear to be ...
 279-315 4.55e-08

RHS Repeat; RHS proteins contain extended repeat regions. These repeats often appear to be involved in ligand binding. Note that this model may not find all the repeats in a protein and that it covers two RHS repeats. The 3D structure of an RHS-repeat-containing protein (the B and C components of an ABC toxin complex) has been determined. The RHS repeats form an extended strip of beta-sheet that spirals around to form a hollow shell, encapsulating the variable C-terminal domain.


Pssm-ID: 461685 [Multi-domain]  Cd Length: 37  Bit Score: 49.90  E-value: 4.55e-08
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 476223761   279 YDNRGRLTSVKDAQGRETRYEYNAAGDLTAVITPDGN 315
Cdd:pfam05593    1 YDAAGRLTSVTDPDGRVTTYTYDAAGRLTAVTDPDGT 37
YD_repeat_2x TIGR01643
YD repeat (two copies); This model describes two tandem copies of a 21-residue extracellular ...
 279-320 5.20e-07

YD repeat (two copies); This model describes two tandem copies of a 21-residue extracellular repeat found in Gram-negative, Gram-positive, and animal proteins. The repeat is named for a YD dipeptide, the most strongly conserved motif of the repeat. These repeats appear in general to be involved in binding carbohydrate; the chicken teneurin-1 YD-repeat region has been shown to bind heparin.


Pssm-ID: 273728 [Multi-domain]  Cd Length: 42  Bit Score: 47.20  E-value: 5.20e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 476223761   279 YDNRGRLTSVKDAQGRETRYEYNAAGDLTAVITPDGNRSETQ 320
Cdd:TIGR01643    1 YDAAGRLTGSTDADGTTTRYTYDAAGRLVEITDADGGSTRYE 42
RhsA COG3209
Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction ...
 1-661 1.22e-05

Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only];


Pssm-ID: 442442 [Multi-domain]  Cd Length: 1103  Bit Score: 49.75  E-value: 1.22e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761    1 MHDPAYPESLPGAPLARYTYTEAGELLAVYDRSNTQVRAFTYDAQHPGRMVAHRYAGRPEMRYRYDDTGRVVEQLNPAGL 80
Cdd:COG3209   322 GTAAVSGAADAGTTTTTGTGTGGTTTTVGGGGSLTLGGYGAAGGLTTSVGAGGGGSTSGSTTTVGGGGTATGSGGGSSTT 401

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761   81 SYRYQYEQDRITVTDSLNRREVLHTEGGAGLKRVVKKELADGSVTHSGYDAAGRLTAQTDAAGRRTEYGLNVVSGDITDI 160
Cdd:COG3209   402 GVGAGTTTTSTTGGDGGPATAAGALTAGGTATGTGTGGGGTTAGTDATTTTGGAGASGTLTTTGGAATGATTGGGTEAGT 481

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  161 TTPDGRETKFYYNDGNQLTAVVSPDGLESRRAYDEPGRLVSETSRSGDVIRYAYDNPHSELPATTTDATGSTRQMTWSRY 240
Cdd:COG3209   482 GGGTLTSGSAGATTLGTDTTLDDTLGGTTTTTAGARGLVVTTGTTLTLGTTTTATLSATDATGTGDTTTTGTVGTGTSTG 561

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  241 GQLLAFTDCSGYQTRYEYDRFGQMTAVHREEGISLYRRYDNRGRLTSVKDAQGRETRYEYNAAGDLTAVITPDGNRSETQ 320
Cdd:COG3209   562 TGGTGTVTTTGDGTGGASTTTGTTGGTATTTTVTTTTTTSTAGTTTTTTSGYTRAGLTLTLGTGTASGLERATASTGSTT 641

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  321 YDAWGKAVSTTQGGLTRSMEYDAAGRVISLTNENGSHSVFSYDALDRLVQQGGFDGRTQRYHYDLTGKLTQSEDEGLVTL 400
Cdd:COG3209   642 GGTTGTGVTTTGTTTTRATGTTGTGTGVTAGLTTLATGGTTVGGGTGTTSTATTGATTGGTETGTTVTTLAGGTTTRLGT 721

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  401 WYYDESDRITHRTVNGEPAEQWQYDDHGWLTDishlsegHRVAVHYGYDDKGRLTGERQTvenpeTGELLWQHETTHAYN 480
Cdd:COG3209   722 TTTGGGGGTTTDGTGTGGTTGTLTTTSTTTTT-------TAGALTYTYDALGRLTSETTP-----GGVTQGTYTTRYTYD 789

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  481 EQGLANRVTPDSLPPVEWLTYGSGYLAGM------KLGDTPLLEYTRDRMHRETVRSFGSMAGSnaaYKLTSTYTPAGQL 554
Cdd:COG3209   790 ALGRLTSVTYPDGETVTYTYDALGRLTSVitvgsgGGTDLQDRTYTYDAAGNITSITDALRAGT---LTQTYTYDALGRL 866

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476223761  555 QSQHLNSLVydRDYGWNDNGDLVRISGpRQTREYGYSATGRLESVRTLApdlDIRIPYATDPAGnrlpDPELHPDSTLTA 634
Cdd:COG3209   867 TSATDPGTT--ESYTYDANGNLTSRTD-GGTTTYTYDALGRLVSVTKPD---GTTTTYTYDALG----HTDHLGSVRALT 936

                         650       660
                  ....*....|....*....|....*..
gi 476223761  635 WPDNRIAEdahyVYHYDEYGRLTEKTD 661
Cdd:COG3209   937 DASGQVVW----RYDYDPFGNLLAETS 959
RHS_repeat pfam05593
RHS Repeat; RHS proteins contain extended repeat regions. These repeats often appear to be ...
 129-166 1.30e-04

RHS Repeat; RHS proteins contain extended repeat regions. These repeats often appear to be involved in ligand binding. Note that this model may not find all the repeats in a protein and that it covers two RHS repeats. The 3D structure of an RHS-repeat-containing protein (the B and C components of an ABC toxin complex) has been determined. The RHS repeats form an extended strip of beta-sheet that spirals around to form a hollow shell, encapsulating the variable C-terminal domain.


Pssm-ID: 461685 [Multi-domain]  Cd Length: 37  Bit Score: 40.27  E-value: 1.30e-04
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 476223761   129 YDAAGRLTAQTDAAGRRTEYGLNvVSGDITDITTPDGR 166
Cdd:pfam05593    1 YDAAGRLTSVTDPDGRVTTYTYD-AAGRLTAVTDPDGT 37
RHS_repeat pfam05593
RHS Repeat; RHS proteins contain extended repeat regions. These repeats often appear to be ...
 341-377 2.66e-04

RHS Repeat; RHS proteins contain extended repeat regions. These repeats often appear to be involved in ligand binding. Note that this model may not find all the repeats in a protein and that it covers two RHS repeats. The 3D structure of an RHS-repeat-containing protein (the B and C components of an ABC toxin complex) has been determined. The RHS repeats form an extended strip of beta-sheet that spirals around to form a hollow shell, encapsulating the variable C-terminal domain.


Pssm-ID: 461685 [Multi-domain]  Cd Length: 37  Bit Score: 39.12  E-value: 2.66e-04
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 476223761   341 YDAAGRVISLTNENGSHSVFSYDALDRLVQQGGFDGR 377
Cdd:pfam05593    1 YDAAGRLTSVTDPDGRVTTYTYDAAGRLTAVTDPDGT 37
RHS_repeat pfam05593
RHS Repeat; RHS proteins contain extended repeat regions. These repeats often appear to be ...
 237-272 3.64e-04

RHS Repeat; RHS proteins contain extended repeat regions. These repeats often appear to be involved in ligand binding. Note that this model may not find all the repeats in a protein and that it covers two RHS repeats. The 3D structure of an RHS-repeat-containing protein (the B and C components of an ABC toxin complex) has been determined. The RHS repeats form an extended strip of beta-sheet that spirals around to form a hollow shell, encapsulating the variable C-terminal domain.


Pssm-ID: 461685 [Multi-domain]  Cd Length: 37  Bit Score: 38.73  E-value: 3.64e-04
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 476223761   237 WSRYGQLLAFTDCSGYQTRYEYDRFGQMTAVHREEG 272
Cdd:pfam05593    1 YDAAGRLTSVTDPDGRVTTYTYDAAGRLTAVTDPDG 36
RHS_repeat pfam05593
RHS Repeat; RHS proteins contain extended repeat regions. These repeats often appear to be ...
 113-144 1.22e-03

RHS Repeat; RHS proteins contain extended repeat regions. These repeats often appear to be involved in ligand binding. Note that this model may not find all the repeats in a protein and that it covers two RHS repeats. The 3D structure of an RHS-repeat-containing protein (the B and C components of an ABC toxin complex) has been determined. The RHS repeats form an extended strip of beta-sheet that spirals around to form a hollow shell, encapsulating the variable C-terminal domain.


Pssm-ID: 461685 [Multi-domain]  Cd Length: 37  Bit Score: 37.58  E-value: 1.22e-03
                           10        20        30
                   ....*....|....*....|....*....|..
gi 476223761   113 RVVKKELADGSVTHSGYDAAGRLTAQTDAAGR 144
Cdd:pfam05593    6 RLTSVTDPDGRVTTYTYDAAGRLTAVTDPDGT 37
RHS_repeat pfam05593
RHS Repeat; RHS proteins contain extended repeat regions. These repeats often appear to be ...
 258-294 5.09e-03

RHS Repeat; RHS proteins contain extended repeat regions. These repeats often appear to be involved in ligand binding. Note that this model may not find all the repeats in a protein and that it covers two RHS repeats. The 3D structure of an RHS-repeat-containing protein (the B and C components of an ABC toxin complex) has been determined. The RHS repeats form an extended strip of beta-sheet that spirals around to form a hollow shell, encapsulating the variable C-terminal domain.


Pssm-ID: 461685 [Multi-domain]  Cd Length: 37  Bit Score: 35.65  E-value: 5.09e-03
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 476223761   258 YDRFGQMTAVHREEGISLYRRYDNRGRLTSVKDAQGR 294
Cdd:pfam05593    1 YDAAGRLTSVTDPDGRVTTYTYDAAGRLTAVTDPDGT 37
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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