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Conserved domains on  [gi|479812671|gb|ENT81472|]
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hypothetical protein H713_02768, partial [Brucella ovis IntaBari-2010-47-268]

Protein Classification

transposase family protein( domain architecture ID 1750073)

transposase family protein might bind to the end of a transposon and catalyze the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism

Gene Ontology:  GO:0003677|GO:0006313
PubMed:  21439812

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
transpos_IS5_3 super family cl41332
IS5 family transposase;
1-101 9.07e-32

IS5 family transposase;


The actual alignment was detected with superfamily member NF033580:

Pssm-ID: 468097 [Multi-domain]  Cd Length: 257  Bit Score: 111.90  E-value: 9.07e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479812671   1 DCAEADALTNELGEG-----DILLADKGYDTNAIRAKAAARKAWANIPPKSNRKgSFVFSRWVYRQRNLVERFFNRIKQF 75
Cdd:NF033580 152 DSKGALPLLDGLPVLrpprpKHLLADKGYDSDALRAALRERGAVPVIPRRRNRL-RPAYDFRLYKKRWVVERTFAWLKRF 230

                         90       100
                 ....*....|....*....|....*.
gi 479812671  76 RGIATRYDKRPENYLAAVKLVATRIW 101
Cdd:NF033580 231 RRLATRYEKLARNFLAFVHLACIRIW 256
 
Name Accession Description Interval E-value
transpos_IS5_3 NF033580
IS5 family transposase;
1-101 9.07e-32

IS5 family transposase;


Pssm-ID: 468097 [Multi-domain]  Cd Length: 257  Bit Score: 111.90  E-value: 9.07e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479812671   1 DCAEADALTNELGEG-----DILLADKGYDTNAIRAKAAARKAWANIPPKSNRKgSFVFSRWVYRQRNLVERFFNRIKQF 75
Cdd:NF033580 152 DSKGALPLLDGLPVLrpprpKHLLADKGYDSDALRAALRERGAVPVIPRRRNRL-RPAYDFRLYKKRWVVERTFAWLKRF 230

                         90       100
                 ....*....|....*....|....*.
gi 479812671  76 RGIATRYDKRPENYLAAVKLVATRIW 101
Cdd:NF033580 231 RRLATRYEKLARNFLAFVHLACIRIW 256
DDE_Tnp_1_2 pfam13586
Transposase DDE domain; Transposase proteins are necessary for efficient DNA transposition. ...
 18-101 6.77e-08

Transposase DDE domain; Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.


Pssm-ID: 463928 [Multi-domain]  Cd Length: 90  Bit Score: 46.26  E-value: 6.77e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479812671   18 LLADKGYDTNAIRAKAAARKAWANIPPKS----NRKGSFVFSRWVYRQRNLVERFFNRIKQFRGIATRYDKRPENYLAAV 93
Cdd:pfam13586   1 VHVDRGYRTRHNREWLKERGIRASGPPLGrpakNKAQEKKQAREDEIARNVIEGKFGWFKRRRSLAKRYEKLASTFEGAI 80


                  ....*...
gi 479812671   94 KLVATRIW 101
Cdd:pfam13586  81 ALTFLVIN 88
transpos_IS5_2 NF033579
IS5 family transposase;
16-74 3.16e-03

IS5 family transposase;


Pssm-ID: 468096 [Multi-domain]  Cd Length: 287  Bit Score: 35.34  E-value: 3.16e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 479812671  16 DILLADKGYDTNAIRAKAAARKAWANIPPKSN------------------RKGSFVFSRWV-YRQRNLVERFFNRIKQ 74
Cdd:NF033579 181 DSVLADGAYDTKKCHEAIRERGARPLIPPRKNarlwkegkarnaaireirRLGRELWKKWSgYHRRSLVETAFSRLKR 258
 
Name Accession Description Interval E-value
transpos_IS5_3 NF033580
IS5 family transposase;
1-101 9.07e-32

IS5 family transposase;


Pssm-ID: 468097 [Multi-domain]  Cd Length: 257  Bit Score: 111.90  E-value: 9.07e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479812671   1 DCAEADALTNELGEG-----DILLADKGYDTNAIRAKAAARKAWANIPPKSNRKgSFVFSRWVYRQRNLVERFFNRIKQF 75
Cdd:NF033580 152 DSKGALPLLDGLPVLrpprpKHLLADKGYDSDALRAALRERGAVPVIPRRRNRL-RPAYDFRLYKKRWVVERTFAWLKRF 230

                         90       100
                 ....*....|....*....|....*.
gi 479812671  76 RGIATRYDKRPENYLAAVKLVATRIW 101
Cdd:NF033580 231 RRLATRYEKLARNFLAFVHLACIRIW 256
DDE_Tnp_1_2 pfam13586
Transposase DDE domain; Transposase proteins are necessary for efficient DNA transposition. ...
 18-101 6.77e-08

Transposase DDE domain; Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.


Pssm-ID: 463928 [Multi-domain]  Cd Length: 90  Bit Score: 46.26  E-value: 6.77e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479812671   18 LLADKGYDTNAIRAKAAARKAWANIPPKS----NRKGSFVFSRWVYRQRNLVERFFNRIKQFRGIATRYDKRPENYLAAV 93
Cdd:pfam13586   1 VHVDRGYRTRHNREWLKERGIRASGPPLGrpakNKAQEKKQAREDEIARNVIEGKFGWFKRRRSLAKRYEKLASTFEGAI 80


                  ....*...
gi 479812671   94 KLVATRIW 101
Cdd:pfam13586  81 ALTFLVIN 88
DDE_Tnp_4 pfam13359
DDE superfamily endonuclease; This family of proteins are related to pfam00665 and are ...
 6-74 1.21e-03

DDE superfamily endonuclease; This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.


Pssm-ID: 463855 [Multi-domain]  Cd Length: 158  Bit Score: 36.10  E-value: 1.21e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 479812671    6 DALTNELGEGDILLADKGYDTNAIRAkaaarkawanIPPKSNRKGSF-----VFSRWVYRQRNLVERFFNRIKQ 74
Cdd:pfam13359  66 KALNLAFGPGDYILADKGFPISDWLL----------VPYKKPGGAQLspeevEFNRRIASARIHVERVIGRLKG 129
transpos_IS5_2 NF033579
IS5 family transposase;
16-74 3.16e-03

IS5 family transposase;


Pssm-ID: 468096 [Multi-domain]  Cd Length: 287  Bit Score: 35.34  E-value: 3.16e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 479812671  16 DILLADKGYDTNAIRAKAAARKAWANIPPKSN------------------RKGSFVFSRWV-YRQRNLVERFFNRIKQ 74
Cdd:NF033579 181 DSVLADGAYDTKKCHEAIRERGARPLIPPRKNarlwkegkarnaaireirRLGRELWKKWSgYHRRSLVETAFSRLKR 258
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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