|
Name |
Accession |
Description |
Interval |
E-value |
| pgi |
PRK00179 |
glucose-6-phosphate isomerase; Reviewed |
10-548 |
0e+00 |
|
glucose-6-phosphate isomerase; Reviewed
Pssm-ID: 234679 Cd Length: 548 Bit Score: 1009.32 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 10 ATVAKLKKHWAESAPRDMRAAFSADPGRFGRYSLCLDDLLFDWSKCRVNDETMALLKELAVAADVEGRRAAMFAGEHINN 89
Cdd:PRK00179 9 PAWQALQAHADEIKDVHLRDLFAADPDRFERFSLTAGGLLLDYSKNRITDETLALLLDLAREAGLEGARDAMFAGEKINT 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 90 TEDRAVLHVALRDTSSKEVLVDGHNVLPDVKHVLDRMAAFADGIRSGALKGATGRKITDIVNIGIGGSDLGPVMATLALA 169
Cdd:PRK00179 89 TEDRAVLHTALRNPSNTPILVDGQDVMPEVHAVLARMKAFAEAVRSGEWKGYTGKAITDVVNIGIGGSDLGPVMVTEALR 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 170 PYHDGP-RAHFVSNIDGAHIADTLSPLDPASTLIIVASKTFTTIETMTNAQTARKWVADTLG-EAAVGAHFAAVSTALDK 247
Cdd:PRK00179 169 PYADPGlRVHFVSNVDGAHLAETLKKLDPETTLFIVASKTFTTQETLTNAHSARDWFLAAGGdEAAVAKHFVAVSTNAEA 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 248 VAAFGIPEDRVFGFWDWVGGRYSVWSAIGLPVMIAVGPDNFRKFLAGAHAMDVHFRDAPLEKNLPVMLGLIGYWHRAICG 327
Cdd:PRK00179 249 VAEFGIDPDNMFGFWDWVGGRYSLWSAIGLSIALAIGPDNFEELLAGAHAMDEHFRTAPLEKNLPVLLALIGVWYRNFFG 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 328 YGSRAIIPYDQRLSRLPAYLQQLDMESNGKSVTLDGKPVSGPTGPVVWGEPGTNGQHAFFQLLHQGTDTIPLEFIVAAKG 407
Cdd:PRK00179 329 AQSHAVLPYDQYLHRFPAYLQQLEMESNGKSVDRDGTPVDYQTGPIIWGEPGTNGQHAFFQLLHQGTKLVPADFIAPAQP 408
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 408 HEPtLDHQHEMLMANCLAQSEALMKGRTLDEARAQLQAKNLPASQVERIAPHRVFSGNRPSLTLIHDMLDPYALGRLIAL 487
Cdd:PRK00179 409 HNP-LGDHHDLLLANCFAQTEALMFGKTAEEVRAELRAKGLDEAEAEELAPHKVFPGNRPSTTILLDRLTPFTLGALIAL 487
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 479816257 488 YEHRVFVEAQIFGINAFDQWGVELGKELATELLPVVSGKEGASGRDASTQGLVAHLHARRK 548
Cdd:PRK00179 488 YEHKVFVQGVIWGINSFDQWGVELGKQLAKRILPELEGDSEASAHDSSTNGLINRYRAWRG 548
|
|
| Pgi |
COG0166 |
Glucose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Glucose-6-phosphate ... |
37-545 |
0e+00 |
|
Glucose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Glucose-6-phosphate isomerase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439936 Cd Length: 484 Bit Score: 731.56 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 37 RFGRYSLCLDDLLFDWSKCRVNDETMALLKELAVAADvegRRAAMFAGEHINNTEDRAVLHVALRDtsskevLVDGHNVL 116
Cdd:COG0166 12 RFERFSLEAAGLLLDYSKNRITDETLELLLELAEEEE---AREALFAGEKINPTEGRAVLHGALRL------PEAGEDVM 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 117 PDVKHVLDRMAAFADGIRsgalkgaTGRKITDIVNIGIGGSDLGPVMATLALAPY-HDGPRAHFVSNIDGAHIADTLSPL 195
Cdd:COG0166 83 PEVREELARIKAFAEKVR-------TGKRITDVVNIGIGGSDLGPRAVIEALKPYfRDGPRVHFVSNVDPDYLAELLAGL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 196 DPASTLIIVASKTFTTIETMTNAQTARKWVADTLGEAaVGAHFAAVSTALDKVAAFGIPED-RVFGFWDWVGGRYSVWSA 274
Cdd:COG0166 156 DPETTLFIVISKSGTTQETLTNARVAREWLEKAGGED-AAKHFVAVTDNAGALRAFGIDEGyNTFPFPDWVGGRYSVLSA 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 275 IGLPVMIAVGPDnFRKFLAGAHAMDVHFRDAPLEKNLPVMLGLIGYWHRAICGYGSRAIIPYDQRLSRLPAYLQQLDMES 354
Cdd:COG0166 235 VGLLPAAAIGID-FEELLAGAHAMDEHFRTAPLEENPPVLLALLGIWYRNFKGAETEAVLPYDQRLERFPAWLQQLWMES 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 355 NGKSVTLDGKPVSGPTGPVvwGEPGTNGQHAFFQLLHQGTDTIPLEFIVAAKGHEPTldhqHEMLMANClaQSEALMKGR 434
Cdd:COG0166 314 NGKSVDRDGNPVGYGTGPV--GEPGTTDQHSFGQLLHQGTRDIPVTFIAVAEPHHDI----PDLLLANL--QGLALLAGK 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 435 TLDEARAQLQAKnlpasqveriAPHRVFSGNRPSLTLIHDMLDPYALGRLIALYEHRVFVEAQIFGINAFDQWGVELGKE 514
Cdd:COG0166 386 TLDEVLALAAEA----------TPHALFPGNRPSNTILLPKLTPYTLGALIALYEHAVFVQGVLWGINPFDQPGVELGKK 455
|
490 500 510
....*....|....*....|....*....|.
gi 479816257 515 LATELLPVVSGKEGASGrdASTQGLVAHLHA 545
Cdd:COG0166 456 LAFALLGKLGGEEAAAG--DSTEALLKRLRA 484
|
|
| PGI |
pfam00342 |
Phosphoglucose isomerase; Phosphoglucose isomerase catalyzes the interconversion of ... |
51-540 |
0e+00 |
|
Phosphoglucose isomerase; Phosphoglucose isomerase catalyzes the interconversion of glucose-6-phosphate and fructose-6-phosphate.
Pssm-ID: 395271 Cd Length: 487 Bit Score: 695.38 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 51 DWSKCRVNDETMALLKELAVAADVEGRRAAMFAGEHINNTEDRAVLHVALRDTSSKEVLVDGHNVLPDVKHVLDRMAAFA 130
Cdd:pfam00342 1 DYSKNHINDEILTALVKLAEERGVDAAREAMFNGEKINSTENRAVLHVALRNRSNTPIYVDGKDVMPEVNAVLAKMKSFS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 131 DGIRSGALKGATGRKITDIVNIGIGGSDLGPVMATLALAPYHD-GPRAHFVSNIDGAHIADTLSPLDPASTLIIVASKTF 209
Cdd:pfam00342 81 ERVRSGEWKGYTGKAITDVVNIGIGGSDLGPVMVTEALKPYSGrDLDVHFVSNVDGTHIAEVLKKLNPETTLFIVASKTF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 210 TTIETMTNAQTARKWVADTLGE-AAVGAHFAAVSTALDKVAAFGIPEDRVFGFWDWVGGRYSVWSAIGLPVMIAVGPDNF 288
Cdd:pfam00342 161 TTAETMTNAESAKEWLLKALKDdSAVAKHFIALSTNAEKVEEFGIDTKNMFEFWDWVGGRYSLWSAIGLPIALSIGFENF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 289 RKFLAGAHAMDVHFRDAPLEKNLPVMLGLIGYWHRAICGYGSRAIIPYDQRLSRLPAYLQQLDMESNGKSVTLDGKPVSG 368
Cdd:pfam00342 241 QQLLEGAHAMDKHFLSAPPEKNIPVLLALLGVWYNNFFGAQTHAILPYDQYLHRFPAYLQQLDMESNGKYVTRDGVLVDH 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 369 PTGPVVWGEPGTNGQHAFFQLLHQGTDTIPLEFIVAAKGHEPTLDHQHEMLMANCLAQSEALMKGRTLDEARAQLQaknl 448
Cdd:pfam00342 321 QTGPIIFGEPGTNGQHAFYQLIHQGTRLIPCDFIGAVQSQNPENGDHHKILLSNFFAQTEALMVGKSPEEVRKELA---- 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 449 pASQVERIAPHRVFSGNRPSLTLIHDMLDPYALGRLIALYEHRVFVEAQIFGINAFDQWGVELGKELATELLPVVSGKEG 528
Cdd:pfam00342 397 -AADVEHLIPHKTFTGNRPSNSILVQKLTPATLGALIAMYEHKIFVQGAIWGINSFDQWGVELGKVLAKSILPELENSNK 475
|
490
....*....|..
gi 479816257 529 ASGRDASTQGLV 540
Cdd:pfam00342 476 VSSHDSSTNGLI 487
|
|
| SIS_PGI_2 |
cd05016 |
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification ... |
330-519 |
2.13e-78 |
|
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of glucose 6-phosphate to fructose 6-phosphate. As an extracellular protein, PGI also has functions equivalent to neuroleukin (NLK), autocrine motility factor (AMF), and maturation factor (MF). Evidence suggests that PGI, NLK, AMF, and MF are closely related or identical. NLK is a neurotrophic growth factor that promotes regeneration and survival of neurons. The dimeric form of NLK has isomerase function, whereas its monomeric form carries out neurotrophic activity. AMF is a cytokine that stimulates cell migration and metastasis. MF mediates the differentiation of human myeloid leukemic HL-60 cells to terminal monocytic cells.
Pssm-ID: 240147 Cd Length: 164 Bit Score: 243.66 E-value: 2.13e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 330 SRAIIPYDQRLSRLPAYLQQLDMESNGKSVTLDGKPVsgPTGPVVWGEPGTNGQHAFFQLLHQGTDTIPLEFIVAAKGHE 409
Cdd:cd05016 2 THALLPYSQRLERFPAWLQQLDMESNGKSVTRDGEDY--PTGPIPWGAPGTNDQHSFFQLIHQGTKDKPVDFIAVKKPQN 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 410 PTLD-----HQHEMLMANCLAQSEALMkgrtldearaqlqaknlpasqveriaphrvFSGNRPSLTLIHDMLDPYALGRL 484
Cdd:cd05016 80 DVLDylagkTLHDLLLANCLATREALM------------------------------FPGGRPSNTIVLPELTPYTLGAL 129
|
170 180 190
....*....|....*....|....*....|....*
gi 479816257 485 IALYEHRVFVEAQIFGINAFDQWGVELGKELATEL 519
Cdd:cd05016 130 LALYEHKTAVQGALLGINPFDQPGVELGKKLAKKI 164
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| pgi |
PRK00179 |
glucose-6-phosphate isomerase; Reviewed |
10-548 |
0e+00 |
|
glucose-6-phosphate isomerase; Reviewed
Pssm-ID: 234679 Cd Length: 548 Bit Score: 1009.32 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 10 ATVAKLKKHWAESAPRDMRAAFSADPGRFGRYSLCLDDLLFDWSKCRVNDETMALLKELAVAADVEGRRAAMFAGEHINN 89
Cdd:PRK00179 9 PAWQALQAHADEIKDVHLRDLFAADPDRFERFSLTAGGLLLDYSKNRITDETLALLLDLAREAGLEGARDAMFAGEKINT 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 90 TEDRAVLHVALRDTSSKEVLVDGHNVLPDVKHVLDRMAAFADGIRSGALKGATGRKITDIVNIGIGGSDLGPVMATLALA 169
Cdd:PRK00179 89 TEDRAVLHTALRNPSNTPILVDGQDVMPEVHAVLARMKAFAEAVRSGEWKGYTGKAITDVVNIGIGGSDLGPVMVTEALR 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 170 PYHDGP-RAHFVSNIDGAHIADTLSPLDPASTLIIVASKTFTTIETMTNAQTARKWVADTLG-EAAVGAHFAAVSTALDK 247
Cdd:PRK00179 169 PYADPGlRVHFVSNVDGAHLAETLKKLDPETTLFIVASKTFTTQETLTNAHSARDWFLAAGGdEAAVAKHFVAVSTNAEA 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 248 VAAFGIPEDRVFGFWDWVGGRYSVWSAIGLPVMIAVGPDNFRKFLAGAHAMDVHFRDAPLEKNLPVMLGLIGYWHRAICG 327
Cdd:PRK00179 249 VAEFGIDPDNMFGFWDWVGGRYSLWSAIGLSIALAIGPDNFEELLAGAHAMDEHFRTAPLEKNLPVLLALIGVWYRNFFG 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 328 YGSRAIIPYDQRLSRLPAYLQQLDMESNGKSVTLDGKPVSGPTGPVVWGEPGTNGQHAFFQLLHQGTDTIPLEFIVAAKG 407
Cdd:PRK00179 329 AQSHAVLPYDQYLHRFPAYLQQLEMESNGKSVDRDGTPVDYQTGPIIWGEPGTNGQHAFFQLLHQGTKLVPADFIAPAQP 408
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 408 HEPtLDHQHEMLMANCLAQSEALMKGRTLDEARAQLQAKNLPASQVERIAPHRVFSGNRPSLTLIHDMLDPYALGRLIAL 487
Cdd:PRK00179 409 HNP-LGDHHDLLLANCFAQTEALMFGKTAEEVRAELRAKGLDEAEAEELAPHKVFPGNRPSTTILLDRLTPFTLGALIAL 487
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 479816257 488 YEHRVFVEAQIFGINAFDQWGVELGKELATELLPVVSGKEGASGRDASTQGLVAHLHARRK 548
Cdd:PRK00179 488 YEHKVFVQGVIWGINSFDQWGVELGKQLAKRILPELEGDSEASAHDSSTNGLINRYRAWRG 548
|
|
| Pgi |
COG0166 |
Glucose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Glucose-6-phosphate ... |
37-545 |
0e+00 |
|
Glucose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Glucose-6-phosphate isomerase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439936 Cd Length: 484 Bit Score: 731.56 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 37 RFGRYSLCLDDLLFDWSKCRVNDETMALLKELAVAADvegRRAAMFAGEHINNTEDRAVLHVALRDtsskevLVDGHNVL 116
Cdd:COG0166 12 RFERFSLEAAGLLLDYSKNRITDETLELLLELAEEEE---AREALFAGEKINPTEGRAVLHGALRL------PEAGEDVM 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 117 PDVKHVLDRMAAFADGIRsgalkgaTGRKITDIVNIGIGGSDLGPVMATLALAPY-HDGPRAHFVSNIDGAHIADTLSPL 195
Cdd:COG0166 83 PEVREELARIKAFAEKVR-------TGKRITDVVNIGIGGSDLGPRAVIEALKPYfRDGPRVHFVSNVDPDYLAELLAGL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 196 DPASTLIIVASKTFTTIETMTNAQTARKWVADTLGEAaVGAHFAAVSTALDKVAAFGIPED-RVFGFWDWVGGRYSVWSA 274
Cdd:COG0166 156 DPETTLFIVISKSGTTQETLTNARVAREWLEKAGGED-AAKHFVAVTDNAGALRAFGIDEGyNTFPFPDWVGGRYSVLSA 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 275 IGLPVMIAVGPDnFRKFLAGAHAMDVHFRDAPLEKNLPVMLGLIGYWHRAICGYGSRAIIPYDQRLSRLPAYLQQLDMES 354
Cdd:COG0166 235 VGLLPAAAIGID-FEELLAGAHAMDEHFRTAPLEENPPVLLALLGIWYRNFKGAETEAVLPYDQRLERFPAWLQQLWMES 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 355 NGKSVTLDGKPVSGPTGPVvwGEPGTNGQHAFFQLLHQGTDTIPLEFIVAAKGHEPTldhqHEMLMANClaQSEALMKGR 434
Cdd:COG0166 314 NGKSVDRDGNPVGYGTGPV--GEPGTTDQHSFGQLLHQGTRDIPVTFIAVAEPHHDI----PDLLLANL--QGLALLAGK 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 435 TLDEARAQLQAKnlpasqveriAPHRVFSGNRPSLTLIHDMLDPYALGRLIALYEHRVFVEAQIFGINAFDQWGVELGKE 514
Cdd:COG0166 386 TLDEVLALAAEA----------TPHALFPGNRPSNTILLPKLTPYTLGALIALYEHAVFVQGVLWGINPFDQPGVELGKK 455
|
490 500 510
....*....|....*....|....*....|.
gi 479816257 515 LATELLPVVSGKEGASGrdASTQGLVAHLHA 545
Cdd:COG0166 456 LAFALLGKLGGEEAAAG--DSTEALLKRLRA 484
|
|
| PGI |
pfam00342 |
Phosphoglucose isomerase; Phosphoglucose isomerase catalyzes the interconversion of ... |
51-540 |
0e+00 |
|
Phosphoglucose isomerase; Phosphoglucose isomerase catalyzes the interconversion of glucose-6-phosphate and fructose-6-phosphate.
Pssm-ID: 395271 Cd Length: 487 Bit Score: 695.38 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 51 DWSKCRVNDETMALLKELAVAADVEGRRAAMFAGEHINNTEDRAVLHVALRDTSSKEVLVDGHNVLPDVKHVLDRMAAFA 130
Cdd:pfam00342 1 DYSKNHINDEILTALVKLAEERGVDAAREAMFNGEKINSTENRAVLHVALRNRSNTPIYVDGKDVMPEVNAVLAKMKSFS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 131 DGIRSGALKGATGRKITDIVNIGIGGSDLGPVMATLALAPYHD-GPRAHFVSNIDGAHIADTLSPLDPASTLIIVASKTF 209
Cdd:pfam00342 81 ERVRSGEWKGYTGKAITDVVNIGIGGSDLGPVMVTEALKPYSGrDLDVHFVSNVDGTHIAEVLKKLNPETTLFIVASKTF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 210 TTIETMTNAQTARKWVADTLGE-AAVGAHFAAVSTALDKVAAFGIPEDRVFGFWDWVGGRYSVWSAIGLPVMIAVGPDNF 288
Cdd:pfam00342 161 TTAETMTNAESAKEWLLKALKDdSAVAKHFIALSTNAEKVEEFGIDTKNMFEFWDWVGGRYSLWSAIGLPIALSIGFENF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 289 RKFLAGAHAMDVHFRDAPLEKNLPVMLGLIGYWHRAICGYGSRAIIPYDQRLSRLPAYLQQLDMESNGKSVTLDGKPVSG 368
Cdd:pfam00342 241 QQLLEGAHAMDKHFLSAPPEKNIPVLLALLGVWYNNFFGAQTHAILPYDQYLHRFPAYLQQLDMESNGKYVTRDGVLVDH 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 369 PTGPVVWGEPGTNGQHAFFQLLHQGTDTIPLEFIVAAKGHEPTLDHQHEMLMANCLAQSEALMKGRTLDEARAQLQaknl 448
Cdd:pfam00342 321 QTGPIIFGEPGTNGQHAFYQLIHQGTRLIPCDFIGAVQSQNPENGDHHKILLSNFFAQTEALMVGKSPEEVRKELA---- 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 449 pASQVERIAPHRVFSGNRPSLTLIHDMLDPYALGRLIALYEHRVFVEAQIFGINAFDQWGVELGKELATELLPVVSGKEG 528
Cdd:pfam00342 397 -AADVEHLIPHKTFTGNRPSNSILVQKLTPATLGALIAMYEHKIFVQGAIWGINSFDQWGVELGKVLAKSILPELENSNK 475
|
490
....*....|..
gi 479816257 529 ASGRDASTQGLV 540
Cdd:pfam00342 476 VSSHDSSTNGLI 487
|
|
| PLN02649 |
PLN02649 |
glucose-6-phosphate isomerase |
14-549 |
0e+00 |
|
glucose-6-phosphate isomerase
Pssm-ID: 215351 [Multi-domain] Cd Length: 560 Bit Score: 636.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 14 KLKKHWAESAPRDMRAAFsADPGRFGRYSLCLDDLLFDWSKCRVNDETMALLKELAVAADVEGRRAAMFAGEHINNTEDR 93
Cdd:PLN02649 16 RLVAHVYQIKKTHLRELL-NDAERCQSMIAEFDGIYLDYSRQRVTDETMELLFPLAEAANLFEKIEAMFSGEIINSTEDR 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 94 AVLHVALRDTSSKEVLVDGHNVLPDVKHVLDRMAAFADGIRSGALKGATGRKITDIVNIGIGGSDLGPVMATLALAPYHD 173
Cdd:PLN02649 95 AVLHVALRAPRLAPILVDGKNVVPEVWEVLDKIKAFSEDVRSGKWKGATGKRFTNVVSIGIGGSFLGPLFVHEALATDPE 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 174 ------GPRAHFVSNIDGAHIADTLSPLDPASTLIIVASKTFTTIETMTNAQTARKWVADTLGEAAVGAHFAAVSTALDK 247
Cdd:PLN02649 175 alksakGRKLRFLANVDPVDIARQIAQLDPETTLVVVVSKTFTTAETMLNARTVRKWLRDALGGLAVAKHMVAVSTNLLL 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 248 VAAFGIPEDRVFGFWDWVGGRYSVWSAIG-LPVMIAVGPDNFRKFLAGAHAMDVHFRDAPLEKNLPVMLGLIGYWHRAIC 326
Cdd:PLN02649 255 VNKFGIDPWNAFPFWDWVGGRYSVCSAVGlLPLSLQYGFDVVEEFLEGAASMDEHFRTAPLKENIPVLLGLLSVWNSSFL 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 327 GYGSRAIIPYDQRLSRLPAYLQQLDMESNGKSVTLDGKPVSGPTGPVVWGEPGTNGQHAFFQLLHQGTdTIPLEFIVAAK 406
Cdd:PLN02649 335 GYPARAILPYSQALLKFAPHIQQLDMESNGKGVDLDGNPLPVNTGEIDFGEPGTNGQHSFYQLIHQGR-NIPCDFIGVVR 413
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 407 GHEPTLDHQ------HEMLMANCLAQSEALMKGRTLDearaQLQAKNLPASQVeriaPHRVFSGNRPSLTLIHDMLDPYA 480
Cdd:PLN02649 414 SQQPVHLWLgegvsnHDELMSNFFAQPDALAYGKTPE----QLRAEGVPEELI----PHKVFAGNRPSLSILLPELTAYT 485
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 479816257 481 LGRLIALYEHRVFVEAQIFGINAFDQWGVELGKELATELLPVVSGK----EGASGRDASTQGLVAHLHARRKA 549
Cdd:PLN02649 486 VGQLLALYEHRVAVQGFIWNINSFDQWGVELGKALAKRVRAVLNEArtkgEPVEGFNSSTTALLNHYLANKRA 558
|
|
| PTZ00430 |
PTZ00430 |
glucose-6-phosphate isomerase; Provisional |
45-545 |
0e+00 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 185612 Cd Length: 552 Bit Score: 585.44 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 45 LDDLLFDWSKCRVNDETMALLKELAVAADVEGRRAAMFAGEHINNTEDRAVLHVALRDTSSKEVLVDGHNVLPDVKHVLD 124
Cdd:PTZ00430 41 FKGVTLDLSRQRLDEETLKLLIELAEEAKLKEKIKDMFNGEKINTTENRAVLHTALRAPRGEKVVVDGKNVLEDVHEVLD 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 125 RMAAFADGIRSGALKGATGRKITDIVNIGIGGSDLGPVMATLALAPYHDGPRA------HFVSNIDGAHIADTLSPLDPA 198
Cdd:PTZ00430 121 RIKKFSDKIRSGEILGSTGKKLKNVICIGIGGSYLGTEFVYEALRTYGEAREAskgrklRFLANVDPIDVRRATEGLDPE 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 199 STLIIVASKTFTTIETMTNAQTARKWVADTLG-EAAVGAHFAAVSTALDKVAAFGIPEDRVFGFWDWVGGRYSVWSAIG- 276
Cdd:PTZ00430 201 ETLVVIISKTFTTAETMLNAKTVRQWLLDNIKsKEALSKHLCAVSTNLKLTSEFGIPDENVFGFWDWVGGRFSVTSAVGi 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 277 LPVMIAVGPDNFRKFLAGAHAMDVHFRDAPLEKNLPVMLGLIGYWHRAICGYGSRAIIPYDQRLSRLPAYLQQLDMESNG 356
Cdd:PTZ00430 281 LPLSIQFGYDIVQQFLNGCHDMDEHFRTAPLEENLPVLLGLTSFYNSTFLGYNCVAILPYCQALLKFPAHVQQLLMESNG 360
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 357 KSVTLDGKPVSGPTGPVVWGEPGTNGQHAFFQLLHQGTdTIPLEFIVAAKGHEPT-LDH----QHEMLMANCLAQSEALM 431
Cdd:PTZ00430 361 KSVTLDGNTLDYNTGEIYFGEPGTNGQHSFYQLLHQGR-VVPSEFIGFAKSQNPIkLLGepvsNHDELMSNFFAQPDALA 439
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 432 KGRTLDearaQLQAKNLPasqvERIAPHRVFSGNRPSLTLIHDMLDPYALGRLIALYEHRVFVEAQIFGINAFDQWGVEL 511
Cdd:PTZ00430 440 FGKTYE----ELEKEGVP----EELIPHKVFPGNRPSLLLLFPELNPYTIGQLLALYEHRTVVEGFLWNINSFDQWGVEL 511
|
490 500 510 520
....*....|....*....|....*....|....*....|.
gi 479816257 512 GKELATELLPVVSGKEGASGRDA-------STQGLVAHLHA 545
Cdd:PTZ00430 512 GKVLAKDVRNLFKDNRSNSSPHAkeskfngSTKRLLSYYLQ 552
|
|
| pgi |
PRK14095 |
glucose-6-phosphate isomerase; Provisional |
35-543 |
1.85e-143 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 237608 Cd Length: 533 Bit Score: 424.43 E-value: 1.85e-143
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 35 PGRFGRYSLCLDDLLFDWSKCRVNDETMALLKELAVAADVEGRRAAMFAGEHINN-----TEDRAVLHVALRDTSSKEVL 109
Cdd:PRK14095 34 EERIKKYSLSGEGFTYNYATERVDDRILAALQNLADEAELIEKMKAMQNGAVINRiegfpSENRPVLHTATRGQVGDSVL 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 110 VD-GHNVLPDVKHVLDRMAAFADGIRSGALKGATGRKITDIVNIGIGGSDLGPVMATLALAPY-HDGPRAHFVSNIDGAH 187
Cdd:PRK14095 114 TDeAEDMAEFSKRELERLAEFLKKVRSGEIKNSNGKKFTTVVQIGIGGSDLGPKALYLALKNYaKKDKRVHFISNVDPDD 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 188 IADTLSPLDPASTLIIVASKTFTTIETMTNAQtarkWVADTLGEAAVGA--HFAAVS---TALDKvaafgiPED--RVFG 260
Cdd:PRK14095 194 AAEVLSEIDLAKTLFIVVSKSGTTLETAANEE----FVRDALKKAGLDYkkHFIAVTsegSPMDD------ESGylEVFH 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 261 FWDWVGGRYSVWSAIGLPVM-IAVGPDNFRKFLAGAHAMDVHFRDAPLEKNLPVMLGLIGYWHRAICGYGSRAIIPYDQR 339
Cdd:PRK14095 264 MWDSIGGRFSSTSMVGGVVLgFAFGFEVFKEFLKGAAAMDKAALNPNIRENLPLLAALIGIWNRNFLGYPTTAVIPYSQA 343
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 340 LSRLPAYLQQLDMESNGKSVTLDGKPVSGPTGPVVWGEPGTNGQHAFFQLLHQGTDTIPLEFIVAAK---GHEPTLD--H 414
Cdd:PRK14095 344 LERFPAHLQQLDMESNGKSVNRFGEPINFKTGPIIWGEPGTNGQHSFFQLLHQGTDIVPVEFIGFKEsqlGQDIVIQgsT 423
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 415 QHEMLMANCLAQSEALMKGRtldearaqlqaknlpasqvERIAPHRVFSGNRPSLTLIHDMLDPYALGRLIALYEHRVFV 494
Cdd:PRK14095 424 SQQKLFANLIAQIIALACGK-------------------ENTNPNKNFKGNRPSSLLVAKQLTPYTLGALLAHYENKVMF 484
|
490 500 510 520
....*....|....*....|....*....|....*....|....*....
gi 479816257 495 EAQIFGINAFDQWGVELGKELATELLPVVSGKEgaSGRDASTQGLVAHL 543
Cdd:PRK14095 485 QGFCWNINSFDQEGVQLGKVLANQILGIMKGEA--PGEFPEADGLLKLF 531
|
|
| SIS_PGI_2 |
cd05016 |
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification ... |
330-519 |
2.13e-78 |
|
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of glucose 6-phosphate to fructose 6-phosphate. As an extracellular protein, PGI also has functions equivalent to neuroleukin (NLK), autocrine motility factor (AMF), and maturation factor (MF). Evidence suggests that PGI, NLK, AMF, and MF are closely related or identical. NLK is a neurotrophic growth factor that promotes regeneration and survival of neurons. The dimeric form of NLK has isomerase function, whereas its monomeric form carries out neurotrophic activity. AMF is a cytokine that stimulates cell migration and metastasis. MF mediates the differentiation of human myeloid leukemic HL-60 cells to terminal monocytic cells.
Pssm-ID: 240147 Cd Length: 164 Bit Score: 243.66 E-value: 2.13e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 330 SRAIIPYDQRLSRLPAYLQQLDMESNGKSVTLDGKPVsgPTGPVVWGEPGTNGQHAFFQLLHQGTDTIPLEFIVAAKGHE 409
Cdd:cd05016 2 THALLPYSQRLERFPAWLQQLDMESNGKSVTRDGEDY--PTGPIPWGAPGTNDQHSFFQLIHQGTKDKPVDFIAVKKPQN 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 410 PTLD-----HQHEMLMANCLAQSEALMkgrtldearaqlqaknlpasqveriaphrvFSGNRPSLTLIHDMLDPYALGRL 484
Cdd:cd05016 80 DVLDylagkTLHDLLLANCLATREALM------------------------------FPGGRPSNTIVLPELTPYTLGAL 129
|
170 180 190
....*....|....*....|....*....|....*
gi 479816257 485 IALYEHRVFVEAQIFGINAFDQWGVELGKELATEL 519
Cdd:cd05016 130 LALYEHKTAVQGALLGINPFDQPGVELGKKLAKKI 164
|
|
| SIS_PGI_1 |
cd05015 |
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification ... |
122-282 |
7.06e-73 |
|
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of glucose 6-phosphate to fructose 6-phosphate. As an extracellular protein, PGI also has functions equivalent to neuroleukin (NLK), autocrine motility factor (AMF), and maturation factor (MF). Evidence suggests that PGI, NLK, AMF, and MF are closely related or identical. NLK is a neurotrophic growth factor that promotes regeneration and survival of neurons. The dimeric form of NLK has isomerase function, whereas its monomeric form carries out neurotrophic activity. AMF is a cytokine that stimulates cell migration and metastasis. MF mediates the differentiation of human myeloid leukemic HL-60 cells to terminal monocytic cells.
Pssm-ID: 240146 Cd Length: 158 Bit Score: 228.95 E-value: 7.06e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 122 VLDRMAAFADGIRSGalkgatgRKITDIVNIGIGGSDLGPVMATLALAPY-HDGPRAHFVSNIDGAHIADTLSPLDPAST 200
Cdd:cd05015 3 ELERIKEFAEKVRSG-------KKITDVVVIGIGGSDLGPRAVYEALKPYfKGGLRLHFVSNVDPDDLAELLKKLDPETT 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 201 LIIVASKTFTTIETMTNAQTARKWVADTLGEaAVGAHFAAVSTALDKVAA-FGIPEDRVFGFWDWVGGRYSV-WSAIGLP 278
Cdd:cd05015 76 LFIVISKSGTTLETLANARLAREWLEEAGGD-DLAKHFVAITDNGSGLLKkAGIEGLNTFEIPDWVGGRFSVlSSVGGLP 154
|
....
gi 479816257 279 VMIA 282
Cdd:cd05015 155 LALA 158
|
|
| pgi |
PRK14096 |
glucose-6-phosphate isomerase; Provisional |
40-520 |
3.94e-57 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 237609 [Multi-domain] Cd Length: 528 Bit Score: 199.34 E-value: 3.94e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 40 RYS--LCLDD---LLFDWSKCRVNDETMALLKEL---AVAAdvegrRAAMFAGEHINNTEDRAVLHVALRDTSskevLVD 111
Cdd:PRK14096 9 RYCdwLYYHPelgLWLDISRMNFDDAFLESLEPKfqkAFAA-----MAALEAGAIANPDEGRMVGHYWLRNPE----LAP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 112 GHNVLPDVKHVLDRMAAFADGIRSGALKGATGRKITDIVNIGIGGSDLGPVMATLALAPYHDGPRAHFVSNIDGAHIADT 191
Cdd:PRK14096 80 TPEIRAEITETLAQIEAFAAKVHSGTIKPPNGEKFTDVLWIGIGGSALGPQFVAEALQPNSDGLNIHFIDNTDPDGIDRV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 192 LSPLDP--ASTLIIVASKTFTTIET---MTNAQTARKwvadtlgeaAVGAHFAAVSTA-------LDKVAafgIPED--R 257
Cdd:PRK14096 160 LAELGDrlATTLVVVISKSGGTPETrngMLEAKAAYE---------AAGLDFASHAVAitmkgskLDQLA---QSEGwlA 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 258 VFGFWDWVGGRYSVWSAIGLpVMIAVGPDNFRKFLAGAHAMDVHFRDAPLEKNlPVMLgLIGYWHRAICGYGSR--AIIP 335
Cdd:PRK14096 228 RFPMWDWVGGRTSETSAVGL-LPAALQGIDIRAFLAGAKQMDEATRVPDLKNN-PAAL-LALAWYYAGDGKGKKdmVVLP 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 336 YDQRLSRLPAYLQQLDMESNGKSVTLDGKPVSgpTGPVVWGEPGTNGQHAFFQLLHQGTDTIPLEFIvaakgheptldhq 415
Cdd:PRK14096 305 YKDRLLLFSRYLQQLVMESLGKELDLDGNVVH--QGIAVYGNKGSTDQHAYVQQLRDGVDNFFVTFI------------- 369
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 416 hEMLMANCLAQSEALMKGRTLDEARAQLQAKnlpasqveRIAphrVFSGNRPSLTLIHDMLDPYALGRLIALYEHRVFVE 495
Cdd:PRK14096 370 -EVLEDRQGSSIEVEPGVTSGDYLSGFLQGT--------RQA---LYENGRQSITITIPEVNPRTLGALIALFERAVGLY 437
|
490 500
....*....|....*....|....*
gi 479816257 496 AQIFGINAFDQWGVELGKELATELL 520
Cdd:PRK14096 438 ASLVNINAYHQPGVEAGKKAAAAIL 462
|
|
| PRK00973 |
PRK00973 |
glucose-6-phosphate isomerase; Provisional |
147-528 |
3.79e-44 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 179193 [Multi-domain] Cd Length: 446 Bit Score: 162.47 E-value: 3.79e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 147 TDIVNIGIGGSDLGPVMATLALAPYH---------DGPRAHFVSNIDGAHIADTLSPLDPASTLIIVASKTFTTIETMTN 217
Cdd:PRK00973 72 DNVVVLGIGGSALGNLALHYALNPLNwnelskeerNGPRVFVLDNVDPEKTASILDVIDLEKTLFNVISKSGNTAETLAN 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 218 AQTARKWVaDTLGEAAVGaHFAAVSTA----LDKVA------AFGIPEDrvfgfwdwVGGRYSVWSAIGLPVMIAVGPDn 287
Cdd:PRK00973 152 YLIIRGIL-EKLGLDPKK-HLVFTTDPekgkLKKIAekegyrTLEIPEN--------VGGRFSVLTPVGLAPAAALGID- 220
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 288 FRKFLAGAHAMDVHFRDAPLEKNLPVMLGLIGYWH--RaicGYGSRAIIPYDQRLSRLPAYLQQLDMESNGKsvtlDGKp 365
Cdd:PRK00973 221 IEELLEGAKEMDKICEKEDIFKNPALLNALIHYLYynR---GKNISVMMPYSERLKYFGDWYRQLWAESLGK----KGV- 292
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 366 vsGPTgPVvwGEPGTNGQHAFFQLLHQGTDTIPLEFIVAAKGHE----PTLDHQHEMLmaNCLAqsealmkGRTLDEA-R 440
Cdd:PRK00973 293 --GQT-PV--KALGATDQHSQLQLYMEGPKDKIITFLKVEKYRRdveiPYEYEDIEEL--SYLG-------GHKLSELiN 358
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 441 AQLQAknlpasqVERIAPHRvfsgNRPSLTLIHDMLDPYALGRLIALYEHRVFVEAQIFGINAFDQWGVELGKELATELL 520
Cdd:PRK00973 359 SEQKG-------TEIALTEN----GRPNVKITLDELNEYTVGQLFYMYEMQTAFMGELLNINAFDQPGVELGKKITYALL 427
|
....*...
gi 479816257 521 pvvsGKEG 528
Cdd:PRK00973 428 ----GRSG 431
|
|
| PRK03868 |
PRK03868 |
glucose-6-phosphate isomerase; Provisional |
145-520 |
3.03e-25 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 235168 Cd Length: 410 Bit Score: 108.10 E-value: 3.03e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 145 KITDIVNIGIGGSDLGPVMATLALAPYHDGPRA-HFVSNIDGAHIADTLSPLDPASTLIIVASKTFTTIETMT------- 216
Cdd:PRK03868 57 SIKNIVVIGIGGSSLGVKAIYSFLKNEKNNKKElHFLENTDPISINKTLSKINLENTLFIVISKSGTTIETISifkylls 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 217 ----NAQTARKWVADTlGEAAVGAHFAAVstalDKVAAFGIPEDrvfgfwdwVGGRYSVWSAIGL-PVMIAvGPDnFRKF 291
Cdd:PRK03868 137 hfklDQELKKNFLFIT-DPDSKLEQFAKE----NNIKCFNIPKN--------VGGRFSVLSAVGIvPLALC-GYD-IKAL 201
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 292 LAGAHAMDVHFRDAPLEKNLPVMLGLIGYWHRaicgYGSRAIIPYDQRLSRLPAYLQQLDMESNGKsvtLDG-KPVSGPT 370
Cdd:PRK03868 202 LEGAKACKDSFFEQKEDHILKKAYFYATHKNA----YNINVLFSYSDALKGFNDWYVQLWGESLGK---KQGyKTRVGLT 274
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 371 gPVvwGEPGTNGQHAFFQLLHQGT----------------DTIP---LEFIvaakghePTLDHQ-----HEMLMANCLAQ 426
Cdd:PRK03868 275 -PI--GLIGSRDQHSFLQLIMEGPrdktvtfikikdfqnaPKIPnisLKGL-------ESLDFVngvsfNELINAQCDAT 344
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 427 SEALMkgrtldearaqlqAKNLPasqVERIaphrvfsgnrpslTLihDMLDPYALGRLIALYEHRVFVEAQIFGINAFDQ 506
Cdd:PRK03868 345 MEALI-------------AEDIP---VDVI-------------TL--EKLDEFSIGYLIYYYELLTSAVGKMLGINTYDQ 393
|
410
....*....|....
gi 479816257 507 WGVELGKELATELL 520
Cdd:PRK03868 394 PGVEVGKRILKEKL 407
|
|
| PRK09533 |
PRK09533 |
bifunctional transaldolase/phosoglucose isomerase; Validated |
123-520 |
1.66e-24 |
|
bifunctional transaldolase/phosoglucose isomerase; Validated
Pssm-ID: 236551 [Multi-domain] Cd Length: 948 Bit Score: 108.13 E-value: 1.66e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 123 LDRMAAFADGIRsgalkgatGRKITDIVNIGIGGSDLGP-VMATlaLAPYHDG-PRAHFVSNIDGAHIADTLSPLDPAST 200
Cdd:PRK09533 440 LAEYEAFAEEVR--------AEGFTDAVVLGMGGSSLGPeVLAE--TFGQRDGfPKLHVLDSTDPAQVRALEAAVDLART 509
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 201 LIIVASKTFTTIETMTNAQTARKWVADTLGEAAvGAHFAAVS---TALDKVAAfgipEDrvfGFWDW------VGGRYSV 271
Cdd:PRK09533 510 LFIVSSKSGGTLEPNIFKDYFFARVKEVLGAKA-GRHFVAVTdpgSSLEKVAK----ED---GFRKIfhgdpdIGGRYSV 581
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 272 WSAIGLPVMIAVGPDnFRKFLAGAHAMdVHF--RDAPLEKNLPVMLGLI-GywHRAICGYGSRAIIpYDQRLSRLPAYLQ 348
Cdd:PRK09533 582 LSPFGLVPAAAAGID-VRALLDSALAM-VRScgPSVPPADNPGVQLGLAlG--VAATQGRDKVTIV-ASPAIADFGAWAE 656
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 349 QLDMESNGKsvtlDGK---PVSGPTgpvvWGEPGTNGQHAFFqlLHQGTDTIPlefivaakgheptlDHQHEmlmancla 425
Cdd:PRK09533 657 QLIAESTGK----EGKgliPIDGEP----LGDPAVYGNDRVF--VYLRLAGEA--------------DAAQD-------- 704
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 426 qsealmkgrtldearAQLQAknlpasqVERiAPHRVFSgnrpsltliHDMLDPYALGRLIALYEHRVFVEAQIFGINAFD 505
Cdd:PRK09533 705 ---------------AALAA-------LEA-AGHPVVR---------IVLDSAEQLGQEFFRWEMATAVAGAVLGINPFD 752
|
410
....*....|....*
gi 479816257 506 QWGVELGKELATELL 520
Cdd:PRK09533 753 QPDVEASKIKTRELT 767
|
|
| pgi |
PRK14097 |
glucose-6-phosphate isomerase; Provisional |
123-528 |
2.06e-14 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 184504 Cd Length: 448 Bit Score: 75.65 E-value: 2.06e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 123 LDRMAAFADGIRSgalkgatgrKITDIVNIGIGGSDLGPVMATLALA-PYH--------DGPRAHFVSN-IDGAHIADTL 192
Cdd:PRK14097 59 FARIKKAAEKIKS---------DSDVLVVIGIGGSYLGARAAIEFLNhSFYnllpkeqrKAPQIIFAGNsISSTYLADLL 129
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90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 193 SPLDPASTLIIVASKTFTTIETMTNAQTARKWVADTLG-EAAVGAHFA---AVSTALDKVA------AFGIPEDrvfgfw 262
Cdd:PRK14097 130 EYLKDKDFSINVISKSGTTTEPAIAFRIFKELLEKKYGkEEAKKRIYAttdKAKGALKTLAdaegyeTFVIPDD------ 203
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170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 263 dwVGGRYSVWSAIGLPVMIAVGPDnFRKFLAGAHAMDVHFRDAPLEKNLPVMLGLIGYW-HRAicGYGSRAIIPYDQRLS 341
Cdd:PRK14097 204 --VGGRFSVLTAVGLLPIAVAGID-IDALMKGAADARKDYSSSDLSENPAYQYAAVRNIlYRK--GYTTEILVNYEPSLQ 278
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250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 342 RLPAYLQQLDMESNGKsvtlDGKpvsG--PTGPVVwgepgTNGQHAFFQLLHQGTDTIpLEFIVAAKG--HEPTLDHQHE 417
Cdd:PRK14097 279 YFSEWWKQLFGESEGK----DQK---GifPASANF-----STDLHSLGQYIQEGRRNL-FETVIKVEKprKDLTIPEDEE 345
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330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 479816257 418 MLMA-NCLAqsealmkGRTLDEAraqlqakNLPASQVERIApHrvFSGNRPSLTLIHDMLDPYALGRLIALYEHRVFVEA 496
Cdd:PRK14097 346 DLDGlNYLA-------GKTVDFV-------NKKAFEGTLLA-H--TDGGVPNIVVNIPELDEYTFGYLVYFFEKACAISG 408
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410 420 430
....*....|....*....|....*....|..
gi 479816257 497 QIFGINAFDQWGVELGKELATELLpvvsGKEG 528
Cdd:PRK14097 409 YLLGVNPFDQPGVEAYKKNMFALL----GKPG 436
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| SIS_TAL_PGI |
cd05798 |
SIS_TAL_PGI: Transaldolase (TAL)/ Phosphoglucose isomerase (PGI). This group represents the ... |
471-519 |
1.20e-03 |
|
SIS_TAL_PGI: Transaldolase (TAL)/ Phosphoglucose isomerase (PGI). This group represents the SIS (Sugar ISomerase) PGI domain, of a multifunctional protein (TAL-PGI ) having both TAL and PGI activities. TAL_PGI contains an N-terminal TAL domain and a C-terminal PGI domain. TAL catalyzes the reversible conversion of sedoheptulose-7-phosphate (S7P) and glyceraldehyde-3-phosphate (G3P), to fructose-6-phosphate (F6P) and erythrose-4-phosphate (E4P). PGI catalyzes the reversible isomerization of F6P to glucose-6-phosphate (G6P). It has been suggested for Gluconobacter oxydans TAL_PGI that this enzyme generates E4P and G6P directly from S7P and G3P. G. oxydans TAL_PGI contributes to increased xylitol production from D-arabitol. As xylitol is an alternative natural sweetner to sucrose, the microbial conversion of D-arabitol to xylitol is of interest to food and pharmaceutical industries.
Pssm-ID: 240224 [Multi-domain] Cd Length: 129 Bit Score: 38.97 E-value: 1.20e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 479816257 471 LIHDMLDPYALGRLIALYEHRVFVEAQIFGINAFDQWGVELGKELATEL 519
Cdd:cd05798 81 IRIDLDDAYDLGQEFFRWEMATAVAGAVLGINPFDQPDVEASKIETRRL 129
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