|
Name |
Accession |
Description |
Interval |
E-value |
| PRK08242 |
PRK08242 |
acetyl-CoA C-acetyltransferase; |
1-401 |
0e+00 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 236197 [Multi-domain] Cd Length: 402 Bit Score: 759.80 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 1 MSEAYIIDAIRTPRGKGKKDGSLYEVKPITLLTTLLNELQQRHQLDTSKVDDIVLGCVTPIGDQGGDIAKTAAIAAGWND 80
Cdd:PRK08242 1 MTEAYIYDAVRTPRGKGKKDGSLHEVKPVRLAAGLLEALRDRNGLDTAAVDDVVLGCVTPVGDQGADIARTAVLAAGLPE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 81 DVAGVQINRFCASGLEAVNMAAMKVRSGWEDLVVAGGVESMSRIPMGSDGGPWALDPETNLKSSFVPQGVGADLIATLDG 160
Cdd:PRK08242 81 TVPGVQINRFCASGLEAVNLAAAKVRSGWDDLVIAGGVESMSRVPMGSDGGAWAMDPSTNFPTYFVPQGISADLIATKYG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 161 YTREDVDTFAVNSQQKAAAAQANGYFDQSVVPVKDHSGVVILEKDEFIKGNTTVEGLTKLNPSFEMMGQM-GFDAIALQK 239
Cdd:PRK08242 161 FSREDVDAYAVESQQRAAAAWAEGYFAKSVVPVKDQNGLTILDHDEHMRPGTTMESLAKLKPSFAMMGEMgGFDAVALQK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 240 YPEAQKINHVHHAGNSSGIVDGAAVVLLASEKAVKEQNLKPRAKVLATALVGTDPTIMLTGPAPAARKALEKAGLTIDDI 319
Cdd:PRK08242 241 YPEVERINHVHHAGNSSGIVDGAAAVLIGSEEAGKALGLKPRARIVATATIGSDPTIMLTGPVPATRKALAKAGLTVDDI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 320 DLFEVNEAFAAVVMRFINELNVPPEKVNVNGGAIALGHPLGATGAMILGTLLDELERQNKKRGLATLCVGGGMGIATIIE 399
Cdd:PRK08242 321 DLFELNEAFASVVLRFMQALDIPHDKVNVNGGAIAMGHPLGATGAMILGTVLDELERRGKRTALITLCVGGGMGIATIIE 400
|
..
gi 480057380 400 RV 401
Cdd:PRK08242 401 RV 402
|
|
| PaaJ |
COG0183 |
Acetyl-CoA acetyltransferase [Lipid transport and metabolism]; Acetyl-CoA acetyltransferase is ... |
1-401 |
3.20e-176 |
|
Acetyl-CoA acetyltransferase [Lipid transport and metabolism]; Acetyl-CoA acetyltransferase is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 439953 [Multi-domain] Cd Length: 391 Bit Score: 496.51 E-value: 3.20e-176
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 1 MSEAYIIDAIRTPRGKgkKDGSLYEVKPITLLTTLLNELQQRHQLDTSKVDDIVLGCVTPIGdQGGDIAKTAAIAAGWND 80
Cdd:COG0183 1 MREVVIVDAVRTPFGR--FGGALADVRADDLGAAVIKALLERAGLDPEAVDDVILGCVLQAG-QGQNPARQAALLAGLPE 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 81 DVAGVQINRFCASGLEAVNMAAMKVRSGWEDLVVAGGVESMSRIPMGSDGGPWALDPETNLKSS-----------FVPQG 149
Cdd:COG0183 78 SVPAVTVNRVCGSGLQAVALAAQAIAAGDADVVIAGGVESMSRAPMLLPKARWGYRMNAKLVDPminpgltdpytGLSMG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 150 VGADLIATLDGYTREDVDTFAVNSQQKAAAAQANGYFDQSVVPV--KDHSGVVILEKDEFIKGNTTVEGLTKLNPSFEMM 227
Cdd:COG0183 158 ETAENVAERYGISREEQDAFALRSHQRAAAAIAAGRFDDEIVPVevPDRKGEVVVDRDEGPRPDTTLEKLAKLKPAFKKD 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 228 GqmgfdaialqkypeaqkinhVHHAGNSSGIVDGAAVVLLASEKAVKEQNLKPRAKVLATALVGTDPTIMLTGPAPAARK 307
Cdd:COG0183 238 G--------------------TVTAGNASGINDGAAALLLMSEEAAKELGLKPLARIVAYAVAGVDPEIMGIGPVPATRK 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 308 ALEKAGLTIDDIDLFEVNEAFAAVVMRFINELNVPPEKVNVNGGAIALGHPLGATGAMILGTLLDELERQNKKRGLATLC 387
Cdd:COG0183 298 ALARAGLTLDDIDLIEINEAFAAQVLAVLRELGLDPDKVNVNGGAIALGHPLGASGARILVTLLHELERRGGRYGLATMC 377
|
410
....*....|....
gi 480057380 388 VGGGMGIATIIERV 401
Cdd:COG0183 378 IGGGQGIALIIERV 391
|
|
| thiolase |
cd00751 |
Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of ... |
5-400 |
1.20e-160 |
|
Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and eukaryotes (cytosol, microbodies and mitochondria). There are 2 functional different classes: thiolase-I (3-ketoacyl-CoA thiolase) and thiolase-II (acetoacetyl-CoA thiolase). Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several biosynthetic pathways.
Pssm-ID: 238383 [Multi-domain] Cd Length: 386 Bit Score: 456.56 E-value: 1.20e-160
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 5 YIIDAIRTPRGKGKkdGSLYEVKPITLLTTLLNELQQRHQLDTSKVDDIVLGCVTPIGdQGGDIAKTAAIAAGWNDDVAG 84
Cdd:cd00751 1 VIVSAVRTPIGRFG--GALKDVSADDLGAAVIKALLERAGLDPEEVDDVIMGNVLQAG-EGQNPARQAALLAGLPESVPA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 85 VQINRFCASGLEAVNMAAMKVRSGWEDLVVAGGVESMSRIPMGSDGGPWALDPETNLKSSFV-----------PQGVGAD 153
Cdd:cd00751 78 TTVNRVCGSGLQAVALAAQSIAAGEADVVVAGGVESMSRAPYLLPKARRGGRLGLNTLDGMLddgltdpftglSMGITAE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 154 LIATLDGYTREDVDTFAVNSQQKAAAAQANGYFDQSVVPV--KDHSGVVILEKDEFIKGNTTVEGLTKLNPSFEMmgqmg 231
Cdd:cd00751 158 NVAEKYGISREEQDEFALRSHQRAAAAQEAGRFKDEIVPVevPGRKGPVVVDRDEGPRPDTTLEKLAKLKPAFKK----- 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 232 fdaialqkypeaqkiNHVHHAGNSSGIVDGAAVVLLASEKAVKEQNLKPRAKVLATALVGTDPTIMLTGPAPAARKALEK 311
Cdd:cd00751 233 ---------------DGTVTAGNASGINDGAAAVLLMSEEKAKELGLKPLARIVGYAVAGVDPAIMGIGPVPAIPKALKR 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 312 AGLTIDDIDLFEVNEAFAAVVMRFINELNVPPEKVNVNGGAIALGHPLGATGAMILGTLLDELERQNKKRGLATLCVGGG 391
Cdd:cd00751 298 AGLTLDDIDLIEINEAFAAQALACLKELGLDPEKVNVNGGAIALGHPLGASGARIVVTLLHELKRRGGRYGLATMCIGGG 377
|
....*....
gi 480057380 392 MGIATIIER 400
Cdd:cd00751 378 QGAAMVIER 386
|
|
| PRK06025 |
PRK06025 |
acetyl-CoA C-acetyltransferase; |
1-401 |
3.98e-153 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 235675 [Multi-domain] Cd Length: 417 Bit Score: 438.83 E-value: 3.98e-153
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 1 MSEAYIIDAIRTPRGKGKK-DGSLYEVKPITLLTTLLNELQQRHQLDTSKVDDIVLGCVTPIGDQGGDIAKTAAIAAGWN 79
Cdd:PRK06025 1 MAEAYIIDAVRTPRGIGKVgKGALAHLHPQHLAATVLKALAERNGLNTADVDDIIWSTSSQRGKQGGDLGRMAALDAGYD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 80 DDVAGVQINRFCASGLEAVNMAAMKVRSGWEDLVVAGGVESMS-------------RIPMGSDGGPWALDpETNLKSSfv 146
Cdd:PRK06025 81 IKASGVTLDRFCGGGITSVNLAAAQIMSGMEDLVIAGGTEMMSytaamaaedmaagKPPLGMGSGNLRLR-ALHPQSH-- 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 147 pQGVGADLIATLDGYTREDVDTFAVNSQQKAAAAQANGYFDQSVVPVKDHSGVVILEKDEFIKGNTTVEGLTKLNPSFEM 226
Cdd:PRK06025 158 -QGVCGDAIATMEGITREALDALGLESQRRAARAIKEGRFDKSLVPVYRDDGSVALDHEEFPRPQTTAEGLAALKPAFTA 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 227 MGQMGFD-------AIALQKYPEAqKINHVHHAGNSSGIVDGAAVVLLASEKAVKEQNLKPRAKVLATALVGTDPTIMLT 299
Cdd:PRK06025 237 IADYPLDdkgttyrGLINQKYPDL-EIKHVHHAGNSSGVVDGAAALLLASKAYAEKHGLKPRARIVAMANMGDDPTLMLN 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 300 GPAPAARKALEKAGLTIDDIDLFEVNEAFAAVVMRFINELNVPPEKVNVNGGAIALGHPLGATGAMILGTLLDELERQNK 379
Cdd:PRK06025 316 APVPAAKKVLAKAGLTKDDIDLWEINEAFAVVAEKFIRDLDLDRDKVNVNGGAIALGHPIGATGSILIGTVLDELERRGL 395
|
410 420
....*....|....*....|..
gi 480057380 380 KRGLATLCVGGGMGIATIIERV 401
Cdd:PRK06025 396 KRGLVTMCAAGGMAPAIIIERV 417
|
|
| AcCoA-C-Actrans |
TIGR01930 |
acetyl-CoA acetyltransferases; This model represents a large family of enzymes which catalyze ... |
6-399 |
4.66e-148 |
|
acetyl-CoA acetyltransferases; This model represents a large family of enzymes which catalyze the thiolysis of a linear fatty acid CoA (or acetoacetyl-CoA) using a second CoA molecule to produce acetyl-CoA and a CoA-ester product two carbons shorter (or, alternatively, the condensation of two molecules of acetyl-CoA to produce acetoacetyl-CoA and CoA). This enzyme is also known as "thiolase", "3-ketoacyl-CoA thiolase", "beta-ketothiolase" and "Fatty oxidation complex beta subunit". When catalyzing the degradative reaction on fatty acids the corresponding EC number is 2.3.1.16. The condensation reaction corresponds to 2.3.1.9. Note that the enzymes which catalyze the condensation are generally not involved in fatty acid biosynthesis, which is carried out by a decarboxylating condensation of acetyl and malonyl esters of acyl carrier proteins. Rather, this activity may produce acetoacetyl-CoA for pathways such as IPP biosynthesis in the absence of sufficient fatty acid oxidation. [Fatty acid and phospholipid metabolism, Other]
Pssm-ID: 273881 [Multi-domain] Cd Length: 385 Bit Score: 424.72 E-value: 4.66e-148
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 6 IIDAIRTPRGKGKkdGSLYEVKPITLLTTLLNELQQRHQLDTSKVDDIVLGCVTPIGDQGgDIAKTAAIAAGWNDDVAGV 85
Cdd:TIGR01930 1 IVAAARTPIGKFG--GSLKDVSAEDLGAAVIKELLERNPLDPELIDDVIFGNVLQAGEQQ-NIARQAALLAGLPESVPAY 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 86 QINRFCASGLEAVNMAAMKVRSGWEDLVVAGGVESMSRIPMG-SDGGPWALDP-----------ETNLKSSFVPQGVGAD 153
Cdd:TIGR01930 78 TVNRQCASGLQAVILAAQLIRAGEADVVVAGGVESMSRVPYGvPRSLRWGVKPgnaeledarlkDLTDANTGLPMGVTAE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 154 LIATLDGYTREDVDTFAVNSQQKAAAAQANGYFDQSVVPVKDH--SGVVILEKDEFIKGNTTVEGLTKLNPSFemmgqmg 231
Cdd:TIGR01930 158 NLAKKYGISREEQDEYALRSHQRAAKAWEEGLFKDEIVPVTVKgrKGPVTVSSDEGIRPNTTLEKLAKLKPAF------- 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 232 fdaialqkypeaqKINHVHHAGNSSGIVDGAAVVLLASEKAVKEQNLKPRAKVLATALVGTDPTIMLTGPAPAARKALEK 311
Cdd:TIGR01930 231 -------------DPDGTVTAGNSSPLNDGAAALLLMSEEKAKELGLTPLARIVSFAVAGVDPEIMGLGPVPAIPKALKK 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 312 AGLTIDDIDLFEVNEAFAAVVMRFINELNVPPEKVNVNGGAIALGHPLGATGAMILGTLLDELERQNKKRGLATLCVGGG 391
Cdd:TIGR01930 298 AGLSISDIDLFEINEAFAAQVLACIKELGLDLEKVNVNGGAIALGHPLGASGARIVTTLLHELKRRGGRYGLATMCIGGG 377
|
....*...
gi 480057380 392 MGIATIIE 399
Cdd:TIGR01930 378 QGAAVILE 385
|
|
| PRK07801 |
PRK07801 |
acetyl-CoA C-acetyltransferase; |
1-401 |
5.29e-124 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181123 [Multi-domain] Cd Length: 382 Bit Score: 363.64 E-value: 5.29e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 1 MSEAYIIDAIRTPrgKGKKDGSLYEVKPITLLTTLLNELQQRHQLDTSKVDDIVLGCVTPIGDQGGDIAKTAAIAAGWND 80
Cdd:PRK07801 1 MAEAYIVDAVRTP--VGKRKGGLAGVHPADLGAHVLKGLVDRTGIDPAAVDDVIFGCVDTIGPQAGNIARTSWLAAGLPE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 81 DVAGVQINRFCASGLEAVNMAAMKVRSGWEDLVVAGGVESMSRIPMGSD---GGPWALDPETNLKSSF--------VPQG 149
Cdd:PRK07801 79 EVPGVTVDRQCGSSQQAIHFAAQAVMSGTQDLVVAGGVQNMSQIPISSAmtaGEQLGFTSPFAESKGWlhrygdqeVSQF 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 150 VGADLIATLDGYTREDVDTFAVNSQQKAAAAQANGYFDQSVVPVKDhsgvviLEKDEFIKgNTTVEGLTKLNPSFEmmgq 229
Cdd:PRK07801 159 RGAELIAEKWGISREEMERFALESHRRAFAAIRAGRFDNEIVPVGG------VTVDEGPR-ETSLEKMAGLKPLVE---- 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 230 mgfdaialqkypeAQKINhvhhAGNSSGIVDGAAVVLLASEKAVKEQNLKPRAKVLATALVGTDPTIMLTGPAPAARKAL 309
Cdd:PRK07801 228 -------------GGRLT----AAVASQISDGASAVLLASERAVKRHGLTPRARIHHLSVRGDDPVFMLTAPIPATRYAL 290
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 310 EKAGLTIDDIDLFEVNEAFAAVVMRFINELNVPPEKVNVNGGAIALGHPLGATGAMILGTLLDELERQNKKRGLATLCVG 389
Cdd:PRK07801 291 EKTGLSIDDIDVVEINEAFAPVVLAWLKETGADPAKVNPNGGAIALGHPLGATGAKLMTTLLHELERTGGRYGLQTMCEG 370
|
410
....*....|..
gi 480057380 390 GGMGIATIIERV 401
Cdd:PRK07801 371 GGTANVTIIERL 382
|
|
| PRK05790 |
PRK05790 |
putative acyltransferase; Provisional |
1-401 |
3.80e-123 |
|
putative acyltransferase; Provisional
Pssm-ID: 180261 [Multi-domain] Cd Length: 393 Bit Score: 361.78 E-value: 3.80e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 1 MSEAYIIDAIRTPRGKGKkdGSLYEVKPITLLTTLLNELQQRHQLDTSKVDDIVLGCVTPIGdQGGDIAKTAAIAAGWND 80
Cdd:PRK05790 1 MKDVVIVSAARTPIGKFG--GALKDVSAVELGAIVIKAALERAGVPPEQVDEVIMGQVLQAG-AGQNPARQAALKAGLPV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 81 DVAGVQINRFCASGLEAVNMAAMKVRSGWEDLVVAGGVESMSRIP---MGSDGGPWALDPEtnLKSSFV----------- 146
Cdd:PRK05790 78 EVPALTINKVCGSGLKAVALAAQAIRAGDADIVVAGGQESMSQAPhvlPGSRWGQKMGDVE--LVDTMIhdgltdafngy 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 147 PQGVGADLIATLDGYTREDVDTFAVNSQQKAAAAQANGYFDQSVVPV--KDHSG-VVILEKDEFIKGNTTVEGLTKLNPS 223
Cdd:PRK05790 156 HMGITAENLAEQYGITREEQDEFALASQQKAEAAIKAGRFKDEIVPVtiKQRKGdPVVVDTDEHPRPDTTAESLAKLRPA 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 224 FEMMGQMgfdaialqkypeaqkinhvhHAGNSSGIVDGAAVVLLASEKAVKEQNLKPRAKVLATALVGTDPTIMLTGPAP 303
Cdd:PRK05790 236 FDKDGTV--------------------TAGNASGINDGAAAVVVMSEAKAKELGLTPLARIVSYAVAGVDPAIMGIGPVP 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 304 AARKALEKAGLTIDDIDLFEVNEAFAAVVMRFINELNVPPEKVNVNGGAIALGHPLGATGAMILGTLLDELERQNKKRGL 383
Cdd:PRK05790 296 AIRKALEKAGWSLADLDLIEINEAFAAQALAVEKELGLDPEKVNVNGGAIALGHPIGASGARILVTLLHEMKRRGAKKGL 375
|
410
....*....|....*...
gi 480057380 384 ATLCVGGGMGIATIIERV 401
Cdd:PRK05790 376 ATLCIGGGQGVALIVERP 393
|
|
| PRK09050 |
PRK09050 |
beta-ketoadipyl CoA thiolase; Validated |
1-401 |
1.37e-109 |
|
beta-ketoadipyl CoA thiolase; Validated
Pssm-ID: 181624 [Multi-domain] Cd Length: 401 Bit Score: 327.30 E-value: 1.37e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 1 MSEAYIIDAIRTPrgKGKKDGSLYEVKPITLLTTLLNELQQRH-QLDTSKVDDIVLGCVTPIGDQGGDIAKTAAIAAGWN 79
Cdd:PRK09050 1 MTEAFICDAIRTP--IGRYGGALSSVRADDLGAVPLKALMARNpGVDWEAVDDVIYGCANQAGEDNRNVARMSALLAGLP 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 80 DDVAGVQINRFCASGLEAVNMAAMKVRSGWEDLVVAGGVESMSRIP--MGSDGGPWALDPE---TNLKSSFV-PQ----- 148
Cdd:PRK09050 79 VSVPGTTINRLCGSGMDAVGTAARAIKAGEAELMIAGGVESMSRAPfvMGKADSAFSRQAEifdTTIGWRFVnPLmkaqy 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 149 GVG-----ADLIATLDGYTREDVDTFAVNSQQKAAAAQANGYFDQSVVPV---KDHSGVVILEKDEFIKGNTTVEGLTKL 220
Cdd:PRK09050 159 GVDsmpetAENVAEDYNISRADQDAFALRSQQRAAAAQAAGFLAEEIVPVtipQKKGDPVVVDRDEHPRPETTLEALAKL 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 221 NPSFEMMGQMGfdaialqkypeaqkinhvhhAGNSSGIVDGAAVVLLASEKAVKEQNLKPRAKVLATALVGTDPTIMLTG 300
Cdd:PRK09050 239 KPVFRPDGTVT--------------------AGNASGVNDGAAALLLASEAAAKKHGLTPRARILGMATAGVEPRIMGIG 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 301 PAPAARKALEKAGLTIDDIDLFEVNEAFAAVVMRFINELNVP--PEKVNVNGGAIALGHPLGATGAMILGTLLDELERQN 378
Cdd:PRK09050 299 PAPATRKLLARLGLTIDQFDVIELNEAFAAQGLAVLRQLGLAddDARVNPNGGAIALGHPLGMSGARLVLTALHQLERTG 378
|
410 420
....*....|....*....|...
gi 480057380 379 KKRGLATLCVGGGMGIATIIERV 401
Cdd:PRK09050 379 GRYALCTMCIGVGQGIALAIERV 401
|
|
| PRK07850 |
PRK07850 |
steroid 3-ketoacyl-CoA thiolase; |
1-401 |
5.20e-108 |
|
steroid 3-ketoacyl-CoA thiolase;
Pssm-ID: 181145 [Multi-domain] Cd Length: 387 Bit Score: 322.83 E-value: 5.20e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 1 MSEAYIIDAIRTPrgKGKKDGSLYEVKPITLLTTLLNELQQRHQLDTSKVDDIVLGCVTPIGDQGGDIAKTAAIAAGWND 80
Cdd:PRK07850 1 MGNPVIVEAVRTP--IGKRNGWLSGLHAAELLGAVQRAVLDRAGIDPGDVEQVIGGCVTQAGEQSNNITRTAWLHAGLPY 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 81 DVAGVQINRFCASGLEAVNMAAMKVRSGWEDLVVAGGVESMSRIPMGSDGGPWALDPETNLKSSFVP-QGVGADLIATLD 159
Cdd:PRK07850 79 HVGATTIDCQCGSAQQANHLVAGLIAAGAIDVGIACGVEAMSRVPLGANAGPGRGLPRPDSWDIDMPnQFEAAERIAKRR 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 160 GYTREDVDTFAVNSQQKAAAAQANGYFDQSVVPVK---------DHSGVVILEKDEFIKgNTTVEGLTKLNPSFEmmgqm 230
Cdd:PRK07850 159 GITREDVDAFGLRSQRRAAQAWAEGRFDREISPVQapvldeegqPTGETRLVTRDQGLR-DTTMEGLAGLKPVLE----- 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 231 gfdaialqkypeaqkiNHVHHAGNSSGIVDGAAVVLLASEKAVKEQNLKPRAKVLATALVGTDPTIMLTGPAPAARKALE 310
Cdd:PRK07850 233 ----------------GGIHTAGTSSQISDGAAAVLWMDEDRARALGLRPRARIVAQALVGAEPYYHLDGPVQATAKVLE 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 311 KAGLTIDDIDLFEVNEAFAAVVMRFINELNVPPEKVNVNGGAIALGHPLGATGAMILGTLLDELERQNKKRGLATLCVGG 390
Cdd:PRK07850 297 KAGMKIGDIDLVEINEAFASVVLSWAQVHEPDMDKVNVNGGAIALGHPVGSTGARLITTALHELERTDKSTALITMCAGG 376
|
410
....*....|.
gi 480057380 391 GMGIATIIERV 401
Cdd:PRK07850 377 ALSTGTIIERI 387
|
|
| PRK06445 |
PRK06445 |
acetyl-CoA C-acetyltransferase; |
1-401 |
1.02e-106 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180563 [Multi-domain] Cd Length: 394 Bit Score: 319.75 E-value: 1.02e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 1 MSEAYIIDAIRTP-----RGKGKKDgSLYEVKPITLLTTLLNELQQRHQLDTSKVDDIVLGCVTPIGDQ---GGdiaKTA 72
Cdd:PRK06445 1 LEDVYLVDFARTAfsrfrPKDPQKD-VFNNIRPEELAAMLINRLIEKTGIKPEEIDDIITGCALQVGENwlyGG---RHP 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 73 AIAAGWNDDVAGVQINRFCASGLEAVNMAAMKVRSGWEDLVVAGGVESMSRIPMGSdgGP-------WALDPET---NLK 142
Cdd:PRK06445 77 IFLARLPYNIPAMAVDRQCASSLTTVSIGAMEIATGMADIVIAGGVEHMTRTPMGD--NPhiepnpkLLTDPKYieyDLT 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 143 SSFVpQGVGADLIATLDGYTREDVDTFAVNSQQKAAAAQANGYFDQSVVPVKDHSG--VVILEKDEFIKGNTTVEGLTKL 220
Cdd:PRK06445 155 TGYV-MGLTAEKLAEEAGIKREEMDRWSLRSHQLAAKAIQEGYFKDEILPIEVEVEgkKKVVDVDQSVRPDTSLEKLAKL 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 221 NPSFemmgqmgfdaialqkypeaqKINHVHHAGNSSGIVDGAAVVLLASEKAVKEQNLKPRAKVLATALVGTDPTIMLTG 300
Cdd:PRK06445 234 PPAF--------------------KPDGVITAGNSSPLNSGASYVLLMSKKAVKKYGLKPMAKIRSFGFAGVPPAIMGKG 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 301 PAPAARKALEKAGLTIDDIDLFEVNEAFAAVVMRFINELNVPPEKVNVNGGAIALGHPLGATGAMILGTLLDELERQNKK 380
Cdd:PRK06445 294 PVPASKKALEKAGLSVKDIDLWEINEAFAVVVLYAIKELGLDPETVNIKGGAIAIGHPLGATGARIVGTLARQLQIKGKD 373
|
410 420
....*....|....*....|.
gi 480057380 381 RGLATLCVGGGMGIATIIERV 401
Cdd:PRK06445 374 YGVATLCVGGGQGGAVVLERV 394
|
|
| fadA |
PRK08947 |
3-ketoacyl-CoA thiolase; Reviewed |
1-401 |
3.56e-104 |
|
3-ketoacyl-CoA thiolase; Reviewed
Pssm-ID: 181592 [Multi-domain] Cd Length: 387 Bit Score: 313.06 E-value: 3.56e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 1 MSEAYIIDAIRTPRGKGKKdGSLYEVKPITLLTTLLNELQQRH-QLDTSKVDDIVLGCVTPIGDQGGDIAKTAAIAAGWN 79
Cdd:PRK08947 1 MEDVVIVDAIRTPMGRSKG-GAFRNVRAEDLSAHLMRSLLARNpALDPAEIDDIIWGCVQQTLEQGFNIARNAALLAGIP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 80 DDVAGVQINRFCASGLEAVNMAAMKVRSGWEDLVVAGGVESMSRIPM--GSDggpwaLDPETNL---KSSFVpQGVGADL 154
Cdd:PRK08947 80 HSVPAVTVNRLCGSSMQALHDAARAIMTGDGDVFLIGGVEHMGHVPMnhGVD-----FHPGLSKnvaKAAGM-MGLTAEM 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 155 IATLDGYTREDVDTFAVNSQQKAAAAQANGYFDQSVVPVKDH--SGVVIL-EKDEFIKGNTTVEGLTKLNPSFEmmgqmg 231
Cdd:PRK08947 154 LGKMHGISREQQDAFAARSHQRAWAATQEGRFKNEIIPTEGHdaDGVLKLfDYDEVIRPETTVEALAALRPAFD------ 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 232 fdaialqkypeaqKINHVHHAGNSSGIVDGAAVVLLASEKAVKEQNLKPRAKVLATALVGTDPTIMLTGPAPAARKALEK 311
Cdd:PRK08947 228 -------------PVNGTVTAGTSSALSDGASAMLVMSESRAKELGLKPRARIRSMAVAGCDPSIMGYGPVPATQKALKR 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 312 AGLTIDDIDLFEVNEAFAA---VVMRFINELNVPPEKVNVNGGAIALGHPLGATGAMILGTLLDELERQNKKRGLATLCV 388
Cdd:PRK08947 295 AGLSISDIDVFELNEAFAAqslPCLKDLGLLDKMDEKVNLNGGAIALGHPLGCSGARISTTLLNLMERKDAQFGLATMCI 374
|
410
....*....|...
gi 480057380 389 GGGMGIATIIERV 401
Cdd:PRK08947 375 GLGQGIATVFERV 387
|
|
| PRK09052 |
PRK09052 |
acetyl-CoA C-acyltransferase; |
1-401 |
7.33e-104 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 181626 [Multi-domain] Cd Length: 399 Bit Score: 312.71 E-value: 7.33e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 1 MSEAYIIDAIRTPRGKGKKdGSLYEVKPITL-LTTLLNELQQRHQLDTSKVDDIVLGCVTPIGDQGGDIAKTAAIAAGWN 79
Cdd:PRK09052 5 LQDAYIVAATRTPVGKAPR-GMFKNTRPDDLlAHVLRSAVAQVPGLDPKLIEDAIVGCAMPEAEQGLNVARIGALLAGLP 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 80 DDVAGVQINRFCASGLEAVNMAAMKVRSGWEDLVVAGGVESMSRIPMGsdGGPWALDPETNLKSSFVP----QGVGADLI 155
Cdd:PRK09052 84 NSVGGVTVNRFCASGLQAVAMAADRIRVGEADVMIAAGVESMSMVPMM--GNKPSMSPAIFARDENVGiaygMGLTAEKV 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 156 ATLDGYTREDVDTFAVNSQQKAAAAQANGYFDQSVVP--VKDH-----SGVVILEK-----DEFIKGNTTVEGLTKLNPS 223
Cdd:PRK09052 162 AEQWKVSREDQDAFALESHQKAIAAQQAGEFKDEITPyeITERfpdlaTGEVDVKTrtvdlDEGPRADTSLEGLAKLKPV 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 224 FEMMGQMGfdaialqkypeaqkinhvhhAGNSSGIVDGAAVVLLASEKAVKEQNLKPRAKVLATALVGTDPTIMLTGPAP 303
Cdd:PRK09052 242 FANKGSVT--------------------AGNSSQTSDGAGAVILVSEKALKQFNLTPLARFVSFAVAGVPPEIMGIGPIE 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 304 AARKALEKAGLTIDDIDLFEVNEAFAAVVMRFINELNVPPEKVNVNGGAIALGHPLGATGAMILGTLLDELERQNKKRGL 383
Cdd:PRK09052 302 AIPAALKQAGLKQDDLDWIELNEAFAAQSLAVIRDLGLDPSKVNPLGGAIALGHPLGATGAIRTATVVHGLRRTNLKYGM 381
|
410
....*....|....*...
gi 480057380 384 ATLCVGGGMGIATIIERV 401
Cdd:PRK09052 382 VTMCVGTGMGAAGIFERL 399
|
|
| PRK06504 |
PRK06504 |
acetyl-CoA C-acetyltransferase; |
1-401 |
2.49e-101 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180595 [Multi-domain] Cd Length: 390 Bit Score: 305.88 E-value: 2.49e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 1 MSEAYIIDAIRTprGKGKKDGSLYEVKPITLLTTLLNELQQRHQLDTSKVDDIVLGCVTPIGDQGGDIAKTAAIAAGWND 80
Cdd:PRK06504 1 MAEAYIVAAART--AGGRKGGRLAGWHPADLAAQVLDALVDRSGADPALIEDVIMGCVSQVGEQATNVARNAVLASKLPE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 81 DVAGVQINRFCASGLEAVNMAAMKVRSGWEDLVVAGGVESMSRIPMGSdggPWALDPETNLKSSFVP------------Q 148
Cdd:PRK06504 79 SVPGTSIDRQCGSSQQALHFAAQAVMSGTMDIVIAAGVESMTRVPMGS---PSTLPAKNGLGHYKSPgmeerypgiqfsQ 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 149 GVGADLIATLDGYTREDVDTFAVNSQQKAAAAQANGYFDQSVVPVK----DHSGVvILEKDEFIKGNTTVEGLTklnpsf 224
Cdd:PRK06504 156 FTGAEMMAKKYGLSKDQLDEFALQSHQRAIAATQAGKFKAEIVPLEitraDGSGE-MHTVDEGIRFDATLEGIA------ 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 225 emmgqmGFDAIAlqkypEAQKINhvhhAGNSSGIVDGAAVVLLASEKAVKEQNLKPRAKVLATALVGTDPTIMLTGPAPA 304
Cdd:PRK06504 229 ------GVKLIA-----EGGRLT----AATASQICDGASGVMVVNERGLKALGVKPLARIHHMTVIGGDPVIMLEAPLPA 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 305 ARKALEKAGLTIDDIDLFEVNEAFAAVVMRFINELNVPPEKVNVNGGAIALGHPLGATGAMILGTLLDELERQNKKRGLA 384
Cdd:PRK06504 294 TERALKKAGMKIDDIDLYEVNEAFASVPLAWLKATGADPERLNVNGGAIALGHPLGASGTKLMTTLVHALKQRGKRYGLQ 373
|
410
....*....|....*..
gi 480057380 385 TLCVGGGMGIATIIERV 401
Cdd:PRK06504 374 TMCEGGGMANVTIVERL 390
|
|
| PRK07851 |
PRK07851 |
acetyl-CoA C-acetyltransferase; |
1-400 |
1.23e-98 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181146 [Multi-domain] Cd Length: 406 Bit Score: 299.61 E-value: 1.23e-98
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 1 MSEAYIIDAIRTPRGKGKKdGSLYEVKPITLLTTLLNE-LQQRHQLDTSKVDDIVLGCVTPIGDQGGDIAKTAAIAAGWn 79
Cdd:PRK07851 1 MPEAVIVSTARSPIGRAFK-GSLKDMRPDDLAAQMVRAaLDKVPALDPTDIDDLMLGCGLPGGEQGFNMARVVAVLLGY- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 80 DDVAGVQINRFCASGLEAVNMAAMKVRSGWEDLVVAGGVESMSRIPMG-SDGGP------------------------WA 134
Cdd:PRK07851 79 DFLPGTTVNRYCSSSLQTTRMAFHAIKAGEGDVFISAGVETVSRFAKGnSDSLPdtknplfaeaqartaaraeggaeaWH 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 135 lDPETN--LKSSFVPQGVGADLIATLDGYTREDVDTFAVNSQQKAAAAQANGYFDQSVVPVKDHSGVVIlEKDEFIKGNT 212
Cdd:PRK07851 159 -DPREDglLPDVYIAMGQTAENVAQLTGISREEQDEWGVRSQNRAEEAIANGFFEREITPVTLPDGTVV-STDDGPRAGT 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 213 TVEGLTKLNPSFEMMGQMGfdaialqkypeaqkinhvhhAGNSSGIVDGAAVVLLASEKAVKEQNLKPRAKVLATALVGT 292
Cdd:PRK07851 237 TYEKVSQLKPVFRPDGTVT--------------------AGNACPLNDGAAAVVIMSDTKARELGLTPLARIVSTGVSGL 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 293 DPTIMLTGPAPAARKALEKAGLTIDDIDLFEVNEAFAAVVMRFINELNVPPEKVNVNGGAIALGHPLGATGAMILGTLLD 372
Cdd:PRK07851 297 SPEIMGLGPVEASKQALARAGMSIDDIDLVEINEAFAAQVLPSARELGIDEDKLNVSGGAIALGHPFGMTGARITTTLLN 376
|
410 420
....*....|....*....|....*...
gi 480057380 373 ELERQNKKRGLATLCVGGGMGIATIIER 400
Cdd:PRK07851 377 NLQTHDKTFGLETMCVGGGQGMAMVLER 404
|
|
| PRK07661 |
PRK07661 |
acetyl-CoA C-acetyltransferase; |
1-401 |
1.36e-96 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181072 [Multi-domain] Cd Length: 391 Bit Score: 293.97 E-value: 1.36e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 1 MSEAYIIDAIRTPRGKGKKdGSLYEVKPITLLTTLLNELQQRHQLDTSKVDDIVLGCVTPIGDQGGDIAKTAAIAAGWND 80
Cdd:PRK07661 1 MREAVIVAGARTPVGKAKK-GSLKTVRPDDLGALVVKETLKRAGNYEGPIDDLIIGCAMPEAEQGLNMARNIGALAGLPY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 81 DVAGVQINRFCASGLEAVNMAAMKVRSGWEDLVVAGGVESMSRIPMGSDggpwALDPETNLKSS----FVPQGVGADLIA 156
Cdd:PRK07661 80 TVPAITINRYCSSGLQSIAYGAERIMLGHSEAVIAGGAESMSLVPMMGH----VVRPNPRLVEAapeyYMGMGHTAEQVA 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 157 TLDGYTREDVDTFAVNSQQKAAAAQANGYFDQSVVPV--------KDHSGV---VILEKDEFIKGNTTVEGLTKLNPSFE 225
Cdd:PRK07661 156 VKYGISREDQDAFAVRSHQRAAKALAEGKFADEIVPVdvtlrtvgENNKLQeetITFSQDEGVRADTTLEILGKLRPAFN 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 226 MMGQMGfdaialqkypeaqkinhvhhAGNSSGIVDGAAVVLLASEKAVKEQNLKPRAKVLATALVGTDPTIMLTGPAPAA 305
Cdd:PRK07661 236 VKGSVT--------------------AGNSSQMSDGAAAVLLMDREKAESDGLKPLAKFRSFAVAGVPPEVMGIGPIAAI 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 306 RKALEKAGLTIDDIDLFEVNEAFAAVVMRFINELNVPPEKVNVNGGAIALGHPLGATGAMILGTLLDELERQNKKRGLAT 385
Cdd:PRK07661 296 PKALKLAGLELSDIGLFELNEAFASQSIQVIRELGLDEEKVNVNGGAIALGHPLGCTGAKLTLSLIHEMKRRNEQFGIVT 375
|
410
....*....|....*.
gi 480057380 386 LCVGGGMGIATIIERV 401
Cdd:PRK07661 376 MCIGGGMGAAGVFELL 391
|
|
| PRK09051 |
PRK09051 |
beta-ketothiolase BktB; |
1-401 |
3.34e-96 |
|
beta-ketothiolase BktB;
Pssm-ID: 181625 [Multi-domain] Cd Length: 394 Bit Score: 293.02 E-value: 3.34e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 1 MSEAYIIDAIRTprGKGKKDGSLYEVKPITLLTTLLNELQQRHQLDTSKVDDIVLGCVTPIGDQGGDIAKTAAIAAGWND 80
Cdd:PRK09051 2 MREVVVVSGVRT--AIGTFGGSLKDVAPTDLGATVVREALARAGVDPDQVGHVVFGHVIPTEPRDMYLSRVAAINAGVPQ 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 81 DVAGVQINRFCASGLEAVNMAAMKVRSGWEDLVVAGGVESMSRIPMGSDGGPW--------ALDPETN-LKSSF--VPQG 149
Cdd:PRK09051 80 ETPAFNVNRLCGSGLQAIVSAAQAILLGDADVAIGGGAESMSRAPYLLPAARWgarmgdakLVDMMVGaLHDPFgtIHMG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 150 VGADLIATLDGYTREDVDTFAVNSQQKAAAAQANGYFDQSVVPV--KDHSGVVILEKDEFIKGNTTVEGLTKLNPSFemm 227
Cdd:PRK09051 160 VTAENVAAKYGISREAQDALALESHRRAAAAIAAGYFKDQIVPVeiKTRKGEVVFDTDEHVRADTTLEDLAKLKPVF--- 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 228 gqmgfdaialqkypeaQKINHVHHAGNSSGIVDGAAVVLLASEKAVKEQNLKPRAKVLATALVGTDPTIMLTGPAPAARK 307
Cdd:PRK09051 237 ----------------KKENGTVTAGNASGINDGAAAVVLAEADAAEARGLKPLARLVGYAHAGVDPEYMGIGPVPATQK 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 308 ALEKAGLTIDDIDLFEVNEAFAAVVMRFINELNVPPEKVNVNGGAIALGHPLGATGAMILGTLLDELERQNKKRGLATLC 387
Cdd:PRK09051 301 ALERAGLTVADLDVIEANEAFAAQACAVTRELGLDPAKVNPNGSGISLGHPVGATGAIITVKALYELQRIGGRYALVTMC 380
|
410
....*....|....
gi 480057380 388 VGGGMGIATIIERV 401
Cdd:PRK09051 381 IGGGQGIAAIFERL 394
|
|
| PRK06205 |
PRK06205 |
acetyl-CoA C-acetyltransferase; |
1-401 |
6.72e-90 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 235741 [Multi-domain] Cd Length: 404 Bit Score: 277.25 E-value: 6.72e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 1 MSEAYIIDAIRTPrgKGKKDGSLYEVKPITLLTTLLNELQQRHQLDTSKVDDIVLGCVTPIGDQGGdIAKTAAIAAGWND 80
Cdd:PRK06205 1 MRDAVICEPVRTP--VGRFGGAFKDVPAEELAATVIRALVERTGIDPARIDDVIFGQGYPNGEAPA-IGRVAALDAGLPV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 81 DVAGVQINRFCASGLEAVNMAAMKVRSGWEDLVVAGGVESMSRIPMGSDGGPW-----------ALDP--ETNLKSSF-V 146
Cdd:PRK06205 78 TVPGMQLDRRCGSGLQAVITAAMQVQTGAADVVIAGGAESMSNVEFYTTDMRWgvrgggvqlhdRLARgrETAGGRRFpV 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 147 PQGV--GADLIATLDGYTREDVDTFAVNSQQKAAAAQANGYFDQSVVPVK---DHSGVVILEKDEFIKGNTTVEGLTKLN 221
Cdd:PRK06205 158 PGGMieTAENLRREYGISREEQDALAVRSHQRAVAAQEAGRFDDEIVPVTvpqRKGDPTVVDRDEHPRADTTLESLAKLR 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 222 PsfemmgqmgfdaIALQKYPEAqkinhVHHAGNSSGIVDGAAVVLLASEKAVKEQNLKPRAKVLATALVGTDPTIMLTGP 301
Cdd:PRK06205 238 P------------IMGKQDPEA-----TVTAGNASGQNDAAAACLVTTEDKAEELGLRPLARLVSWAVAGVEPSRMGIGP 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 302 APAARKALEKAGLTIDDIDLFEVNEAFAAVVMRFINELNVPP---EKVNVNGGAIALGHPLGATGAMILGTLLDELERQN 378
Cdd:PRK06205 301 VPATEKALARAGLTLDDIDLIELNEAFAAQVLAVLKEWGFGAddeERLNVNGSGISLGHPVGATGGRILATLLRELQRRQ 380
|
410 420
....*....|....*....|...
gi 480057380 379 KKRGLATLCVGGGMGIATIIERV 401
Cdd:PRK06205 381 ARYGLETMCIGGGQGLAAVFERV 403
|
|
| PRK08131 |
PRK08131 |
3-oxoadipyl-CoA thiolase; |
1-401 |
6.18e-87 |
|
3-oxoadipyl-CoA thiolase;
Pssm-ID: 181242 [Multi-domain] Cd Length: 401 Bit Score: 269.34 E-value: 6.18e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 1 MSEAYIIDAIRTPRGKgkKDGSLYEVKPITLLTTLLNELQQRHQLDTSKVDDIVLGCVTPIGDQGGDIAKTAAIAAGWND 80
Cdd:PRK08131 1 MLDAYIYDGLRSPFGR--HAGALASVRPDDLAATVIRRLLEKSGFPGDDIEDVILGCTNQAGEDSRNVARNALLLAGLPV 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 81 DVAGVQINRFCASGLEAVNMAAMKVRSGWEDLVVAGGVESMSRIP--MGSDGGPWALDPE---TNLKSSF---------- 145
Cdd:PRK08131 79 TVPGQTVNRLCASGLAAVIDAARAITCGEGDLYLAGGVESMSRAPfvMGKAESAFSRDAKvfdTTIGARFpnpkivaqyg 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 146 ---VPQGvgADLIATLDGYTREDVDTFAVNSQQKAAAAQANGYFDQSVVPVKDHSG----VVILEKDEFIKGNTTVEGLT 218
Cdd:PRK08131 159 ndsMPET--GDNVAAEFGISREDADRFAAQSQAKYQAAKEEGFFADEITPIEVPQGrklpPKLVAEDEHPRPSSTVEALT 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 219 KLNPSFEmmgqmgfdaialqkypeaqkiNHVHHAGNSSGIVDGAAVVLLASEKAVKEQNLKPRAKVLATALVGTDPTIML 298
Cdd:PRK08131 237 KLKPLFE---------------------GGVVTAGNASGINDGAAALLIGSRAAGEKYGLKPMARILSSAAAGVEPRIMG 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 299 TGPAPAARKALEKAGLTIDDIDLFEVNEAFAAVVMRFINELNVP--PEKVNVNGGAIALGHPLGATGAMILGTLLDELER 376
Cdd:PRK08131 296 IGPVEAIKKALARAGLTLDDMDIIEINEAFASQVLGCLKGLGVDfdDPRVNPNGGAIAVGHPLGASGARLALTAARELQR 375
|
410 420
....*....|....*....|....*
gi 480057380 377 QNKKRGLATLCVGGGMGIATIIERV 401
Cdd:PRK08131 376 RGKRYAVVSLCIGVGQGLAMVIERV 400
|
|
| PLN02287 |
PLN02287 |
3-ketoacyl-CoA thiolase |
6-400 |
6.79e-87 |
|
3-ketoacyl-CoA thiolase
Pssm-ID: 215161 [Multi-domain] Cd Length: 452 Bit Score: 270.87 E-value: 6.79e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 6 IIDAIRTPRGKGKKdGSLYEVKPITLLTTLLNELQQRHQLDTSKVDDIVLGCVTPIGDQGGDIAKTAAIAAGWNDDVAGV 85
Cdd:PLN02287 50 IVAAYRTPICKAKR-GGFKDTYPDDLLAPVLKAVVEKTGLNPSEVGDIVVGTVLAPGSQRANECRMAAFYAGFPETVPVR 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 86 QINRFCASGLEAVNMAAMKVRSGWEDLVVAGGVESMSRIPMGSDGGpwaLDPETNL----KSSFVPQGVGADLIATLDGY 161
Cdd:PLN02287 129 TVNRQCSSGLQAVADVAAAIKAGFYDIGIGAGVESMTTNPMAWEGG---VNPRVESfsqaQDCLLPMGITSENVAERFGV 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 162 TREDVDTFAVNSQQKAAAAQANGYFDQSVVPVKDH--------SGVVILEKDEFIKGNTTVEGLTKLNPSFemmgqmgfd 233
Cdd:PLN02287 206 TREEQDQAAVESHRKAAAATASGKFKDEIVPVHTKivdpktgeEKPIVISVDDGIRPNTTLADLAKLKPVF--------- 276
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 234 aialqkypeaqKINHVHHAGNSSGIVDGAAVVLLASEKAVKEQNLKPRAKVLATALVGTDPTIMLTGPAPAARKALEKAG 313
Cdd:PLN02287 277 -----------KKNGTTTAGNSSQVSDGAGAVLLMKRSVAMQKGLPILGVFRSFAAVGVDPAVMGIGPAVAIPAAVKAAG 345
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 314 LTIDDIDLFEVNEAFAAVVMRFINELNVPPEKVNVNGGAIALGHPLGATGAMILGTLLDELERQNK--KRGLATLCVGGG 391
Cdd:PLN02287 346 LELDDIDLFEINEAFASQFVYCCKKLGLDPEKVNVNGGAIALGHPLGATGARCVATLLHEMKRRGKdcRFGVVSMCIGTG 425
|
....*....
gi 480057380 392 MGIATIIER 400
Cdd:PLN02287 426 MGAAAVFER 434
|
|
| PRK08235 |
PRK08235 |
acetyl-CoA C-acetyltransferase; |
1-399 |
2.53e-82 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181311 [Multi-domain] Cd Length: 393 Bit Score: 257.33 E-value: 2.53e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 1 MSEAYIIDAIRTPRGKgkKDGSLYEVKPITLLTTLLNELQQRHQLDTSKVDDIVLGCVTPIGdQGGDIAKTAAIAAGWND 80
Cdd:PRK08235 1 MSKTVIVSAARTPFGK--FGGSLKDVKATELGGIAIKEALERANVSAEDVEEVIMGTVLQGG-QGQIPSRQAARAAGIPW 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 81 DVAGVQINRFCASGLEAVNMAAMKVRSGWEDLVVAGGVESMSRIPMGSDGGPWAL---DPET-------NLKSSF--VPQ 148
Cdd:PRK08235 78 EVQTETVNKVCASGLRAVTLADQIIRAGDASVIVAGGMESMSNAPYILPGARWGYrmgDNEVidlmvadGLTCAFsgVHM 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 149 GVGADLIATLDGYTREDVDTFAVNSQQKAAAAQANGYFDQSVVPV---KDHSGVVILEKDEFIKGNTTVEGLTKLNPSFE 225
Cdd:PRK08235 158 GVYGGEVAKELGISREAQDEWAYRSHQRAVSAHEEGRFEEEIVPVtipQRKGDPIVVAKDEAPRKDTTIEKLAKLKPVFD 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 226 MMGQMGfdaialqkypeaqkinhvhhAGNSSGIVDGAAVVLLASEKAVKEQNLKPRAKVLATALVGTDPTIMLTGPAPAA 305
Cdd:PRK08235 238 KTGTIT--------------------AGNAPGVNDGAAALVLMSEDRAKQEGRKPLATILAHTAIAVEAKDFPRTPGYAI 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 306 RKALEKAGLTIDDIDLFEVNEAFAAVVMRFINELNVPPEKVNVNGGAIALGHPLGATGAMILGTLLDELERQNKKRGLAT 385
Cdd:PRK08235 298 NALLEKTGKTVEDIDLFEINEAFAAVALASTEIAGIDPEKVNVNGGAVALGHPIGASGARIIVTLIHELKRRGGGIGIAA 377
|
410
....*....|....
gi 480057380 386 LCVGGGMGIATIIE 399
Cdd:PRK08235 378 ICSGGGQGDAVLIE 391
|
|
| PRK06633 |
PRK06633 |
acetyl-CoA C-acetyltransferase; |
3-401 |
3.05e-78 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 168632 [Multi-domain] Cd Length: 392 Bit Score: 246.87 E-value: 3.05e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 3 EAYIIDAIRTPRGKGKkdGSLYEVKPITLLTTLLNELQQRHQLDTSKVDDIVLGCVTpIGDQGGDIAKTAAIAAGWNDDV 82
Cdd:PRK06633 4 PVYITHAKRTAFGSFM--GSLSTTPAPMLAAHLIKDILQNSKIDPALVNEVILGQVI-TGGSGQNPARQTLIHAGIPKEV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 83 AGVQINRFCASGLEAVNMAAMKVRSGWEDLVVAGGVESMS------RIPMGSDGGPWAL------DPETNLKSSfVPQGV 150
Cdd:PRK06633 81 PGYTINKVCGSGLKSVALAANSIMTGDNEIVIAGGQENMSlgmhgsYIRAGAKFGDIKMvdlmqyDGLTDVFSG-VFMGI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 151 GADLIATLDGYTREDVDTFAVNSQQKAAAAQANGYFDQSVVPVKD--HSGVVILEKDEFIKGNTTVEGLTKLNPSFEMmg 228
Cdd:PRK06633 160 TAENISKQFNISRQEQDEFALSSHKKAAKAQLAGIFKDEILPIEVtiKKTTSLFDHDETVRPDTSLEILSKLRPAFDK-- 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 229 qmgfdaialqkypeaqkiNHVHHAGNSSGIVDGAAVVLLASEKAVKEQNLKPRAKVLATALVGTDPTIMLTGPAPAARKA 308
Cdd:PRK06633 238 ------------------NGVVTAGNASSINDGAACLMVVSEEALKKHNLTPLARIVSYASAGVDPSIMGTAPVPASQKA 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 309 LEKAGLTIDDIDLFEVNEAFAAVVMRFINELNVPPEKVNVNGGAIALGHPLGATGAMILGTLLDELERQNKKRGLATLCV 388
Cdd:PRK06633 300 LSKAGWSVNDLEVIEVNEAFAAQSIYVNREMKWDMEKVNINGGAIAIGHPIGASGGRVLITLIHGLRRAKAKKGLVTLCI 379
|
410
....*....|...
gi 480057380 389 GGGMGIATIIERV 401
Cdd:PRK06633 380 GGGMGMAMCVEAV 392
|
|
| PRK08170 |
PRK08170 |
acetyl-CoA C-acetyltransferase; |
5-401 |
4.15e-76 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181265 [Multi-domain] Cd Length: 426 Bit Score: 242.23 E-value: 4.15e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 5 YIIDAIRTPRGKGKkdGSLYEVKPITLLTTLLNELQQRHQLDTSKVDDIVLGCVTPIGDQGgDIAKTAAIAAGWNDDVAG 84
Cdd:PRK08170 6 YIVDGARTPFLKAR--GGPGPFSASDLAVAAGRALLNRQPFAPDDLDEVILGCAMPSPDEA-NIARVVALRLGCGEKVPA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 85 VQINRFCASGLEAVNMAAMKVRSGWEDLVVAGGVESMSRIPM--GSDGGPW------ALDPETNLKS--SFVPQ------ 148
Cdd:PRK08170 83 WTVQRNCASGMQALDSAAANIALGRADLVLAGGVEAMSHAPLlfSEKMVRWlagwyaAKSIGQKLAAlgKLRPSylapvi 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 149 ---------------GVGADLIATLDGYTREDVDTFAVNSQQKAAAAQANGYFDQsVVPVKDHSGVViLEKDEFIKGNTT 213
Cdd:PRK08170 163 gllrgltdpvvglnmGQTAEVLAHRFGITREQMDAYAARSHQRLAAAQAEGRLKE-VVPLFDRDGKF-YDHDDGVRPDSS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 214 VEGLTKLNPSFEmmgqmgfdaialQKYPEAQkinhvhhAGNSSGIVDGAAVVLLASEKAVKEQNLKPRAKVLATALVGTD 293
Cdd:PRK08170 241 MEKLAKLKPFFD------------RPYGRVT-------AGNSSQITDGACWLLLASEEAVKKYGLPPLGRIVDSQWAALD 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 294 PTIMLTGPAPAARKALEKAGLTIDDIDLFEVNEAFAAVVMRFINELN-----------------VPPEKVNVNGGAIALG 356
Cdd:PRK08170 302 PSQMGLGPVHAATPLLQRHGLTLEDLDLWEINEAFAAQVLACLAAWAdeeycreqlgldgalgeLDRERLNVDGGAIALG 381
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 480057380 357 HPLGATGAMILGTLLDELERQNKKRGLATLCVGGGMGIATIIERV 401
Cdd:PRK08170 382 HPVGASGARIVLHLLHALKRRGTKRGIAAICIGGGQGGAMLLERV 426
|
|
| PRK07108 |
PRK07108 |
acetyl-CoA C-acyltransferase; |
1-399 |
1.03e-73 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 180843 [Multi-domain] Cd Length: 392 Bit Score: 235.05 E-value: 1.03e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 1 MSEAYIIDAIRTPRGKGKKdGSLYEVKPITLLTTLLNELQQRHQLDTSKVDDIVLGCVTPIGDQGGDIAKTAAIAAGWND 80
Cdd:PRK07108 1 MTEAVIVSTARTPLAKSWR-GAFNMTHGATLGGHVVQHAVERAKLDPAEVEDVIMGCANPEGATGANIARQIALRAGLPV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 81 DVAGVQINRFCASGLEAVNMAAMKVRSGWEDLVVAGGVESMSRIPMGSD----GGPWALDPETNLKSSFVPQgvgADLIA 156
Cdd:PRK07108 80 TVPGMTVNRFCSSGLQTIALAAQRVIAGEGDVFVAGGVESISCVQNEMNrhmlREGWLVEHKPEIYWSMLQT---AENVA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 157 TLDGYTREDVDTFAVNSQQKAAAAQANGYFDQSVVPVKDHSGV------------VILEKDEFIKGNTTVEGLTKLNPSF 224
Cdd:PRK07108 157 KRYGISKERQDEYGVQSQQRAAAAQAAGRFDDEIVPITVTAGVadkatgrlftkeVTVSADEGIRPDTTLEGVSKIRSAL 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 225 EmmgqmgfdaialqkypeaqkiNHVHHAGNSSGIVDGAAVVLLASEKAVKEQNLKPRAKVLATALVGTDPTIMLTGPAPA 304
Cdd:PRK07108 237 P---------------------GGVITAGNASQFSDGASACVVMNAKVAEREGLQPLGIFRGFAVAGCEPDEMGIGPVFA 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 305 ARKALEKAGLTIDDIDLFEVNEAFAAVVMRFINELNVPPEKVNVNGGAIALGHPLGATGAMILGTLLDELERQNKKRGLA 384
Cdd:PRK07108 296 VPKLLKQAGLKVDDIDLWELNEAFAVQVLYCRDTLGIPMDRLNVNGGAIAVGHPYGVSGARLTGHALIEGKRRGAKYVVV 375
|
410
....*....|....*
gi 480057380 385 TLCVGGGMGIATIIE 399
Cdd:PRK07108 376 TMCIGGGQGAAGLFE 390
|
|
| PRK05656 |
PRK05656 |
acetyl-CoA C-acetyltransferase; |
1-400 |
2.64e-72 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 168156 Cd Length: 393 Bit Score: 231.32 E-value: 2.64e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 1 MSEAYIIDAIRTPRGKGKkdGSLYEVKPITLLTTLLNELQQRHQLDTSKVDDIVLGCVTPIGdQGGDIAKTAAIAAGWND 80
Cdd:PRK05656 1 MQDVVIVAATRTAIGSFQ--GSLANIPAVELGAAVIRRLLEQTGLDPAQVDEVILGQVLTAG-AGQNPARQAAIKAGLPH 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 81 DVAGVQINRFCASGLEAVNMAAMKVRSGWEDLVVAGGVESMSRIPMGSDGGPWALD-PETNLKSSFVPQ----------- 148
Cdd:PRK05656 78 SVPAMTLNKVCGSGLKALHLAAQAIRCGDAEVIIAGGQENMSLAPYVLPGARTGLRmGHAQLVDSMITDglwdafndyhm 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 149 GVGADLIATLDGYTREDVDTFAVNSQQKAAAAQANGYFDQSVVPV---KDHSGVVILEKDEFIKGNTTVEGLTKLNPSFE 225
Cdd:PRK05656 158 GITAENLVEKYGISREAQDAFAAASQQKAVAAIEAGRFDDEITPIlipQRKGEPLAFATDEQPRAGTTAESLAKLKPAFK 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 226 MMGQMGfdaialqkypeaqkinhvhhAGNSSGIVDGAAVVLLASEKAVKEQNLKPRAKVLATALVGTDPTIMLTGPAPAA 305
Cdd:PRK05656 238 KDGSVT--------------------AGNASSLNDGAAAVLLMSAAKAKALGLPVLAKIAAYANAGVDPAIMGIGPVSAT 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 306 RKALEKAGLTIDDIDLFEVNEAFAAVVMRFINELNVPPEKVNVNGGAIALGHPLGATGAMILGTLLDELERQNKKRGLAT 385
Cdd:PRK05656 298 RRCLDKAGWSLAELDLIEANEAFAAQSLAVGKELGWDAAKVNVNGGAIALGHPIGASGCRVLVTLLHEMIRRDAKKGLAT 377
|
410
....*....|....*
gi 480057380 386 LCVGGGMGIATIIER 400
Cdd:PRK05656 378 LCIGGGQGVALAIER 392
|
|
| PRK06366 |
PRK06366 |
acetyl-CoA C-acetyltransferase; |
1-401 |
4.91e-69 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 102340 [Multi-domain] Cd Length: 388 Bit Score: 222.96 E-value: 4.91e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 1 MSEAYIIDAIRTPRGKGKKdgSLYEVKPITLLTTLLNELQQRHQLDTSKVDDIVLGCVTPIGDqGGDIAKTAAIAAGWND 80
Cdd:PRK06366 1 MKDVYIVSAKRTAIGKFGR--SFSKIKAPQLGGAAIKAVIDDAKLDPALVQEVIMGNVIQAGV-GQNPAGQAAYHAGLPF 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 81 DVAGVQINRFCASGLEAVNMAAMKVRSGWEDLVVAGGVESMSRIP--MGSD--GGPWALdPETNLKSS------------ 144
Cdd:PRK06366 78 GVTKYTVNVVCASGMLAVESAAREIMLGERDLVIAGGMENMSNAPflLPSDlrWGPKHL-LHKNYKIDdamlvdglidaf 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 145 -FVPQGVGADLIATLDGYTREDVDTFAVNSQQKAAAAQANGYFDQSVVPVKDhsgvviLEKDEFIKgNTTVEGLTKLNPS 223
Cdd:PRK06366 157 yFEHMGVSAERTARKYGITREMADEYSVQSYERAIRATESGEFRNEIVPFND------LDRDEGIR-KTTMEDLAKLPPA 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 224 FEMMGqmgfdaialqkypeaqkinhVHHAGNSSGIVDGAAVVLLASEKAVKEQNLKPRAKVLATALVGTDPTIMLTGPAP 303
Cdd:PRK06366 230 FDKNG--------------------ILTAGNSAQLSDGGSALVMASEKAINEYGLKPIARITGYESASLDPLDFVEAPIP 289
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 304 AARKALEKAGLTIDDIDLFEVNEAF--AAVVMRfiNELNVPPEKVNVNGGAIALGHPLGATGAMILGTLLDELERQNKKR 381
Cdd:PRK06366 290 ATRKLLEKQNKSIDYYDLVEHNEAFsiASIIVR--DQLKIDNERFNVNGGAVAIGHPIGNSGSRIIVTLINALKTRHMKT 367
|
410 420
....*....|....*....|
gi 480057380 382 GLATLCVGGGMGIATIIERV 401
Cdd:PRK06366 368 GLATLCHGGGGAHTLTLEMV 387
|
|
| PLN02644 |
PLN02644 |
acetyl-CoA C-acetyltransferase |
6-401 |
2.10e-68 |
|
acetyl-CoA C-acetyltransferase
Pssm-ID: 215347 [Multi-domain] Cd Length: 394 Bit Score: 221.51 E-value: 2.10e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 6 IIDAIRTPRGKGKkdGSLYEVKPITLLTTLLNELQQRHQLDTSKVDDIVLGCVTPIGdQGGDIAKTAAIAAGWNDDVAGV 85
Cdd:PLN02644 5 IVGVARTPIGGFL--GSLSSLSATELGSIAIQAALERAGVDPALVQEVFFGNVLSAN-LGQAPARQAALGAGLPPSTICT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 86 QINRFCASGLEAVNMAAMKVRSGWEDLVVAGGVESMSRIPM-------GS--------DG----GPWalDPETNlkssfV 146
Cdd:PLN02644 82 TVNKVCASGMKAVMLAAQSIQLGINDVVVAGGMESMSNAPKylpearkGSrlghdtvvDGmlkdGLW--DVYND-----F 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 147 PQGVGADLIATLDGYTREDVDTFAVNSQQKAAAAQANGYFDQSVVPVKDHSG----VVILEKDEFIkGNTTVEGLTKLNP 222
Cdd:PLN02644 155 GMGVCAELCADQYSISREEQDAYAIQSYERAIAAQEAGAFAWEIVPVEVPGGrgrpSVIVDKDEGL-GKFDPAKLRKLRP 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 223 SFEmmgqmgfdaialqkypeaQKINHVHhAGNSSGIVDGAAVVLLASEKAVKEQNLKPRAKVLATALVGTDPTIMLTGPA 302
Cdd:PLN02644 234 SFK------------------EDGGSVT-AGNASSISDGAAALVLVSGEKALELGLQVIAKIRGYADAAQAPELFTTAPA 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 303 PAARKALEKAGLTIDDIDLFEVNEAFAAVVMRFINELNVPPEKVNVNGGAIALGHPLGATGAMILGTLLDELERQNKKRG 382
Cdd:PLN02644 295 LAIPKALKHAGLEASQVDYYEINEAFSVVALANQKLLGLDPEKVNVHGGAVSLGHPIGCSGARILVTLLGVLRSKNGKYG 374
|
410
....*....|....*....
gi 480057380 383 LATLCVGGGMGIATIIERV 401
Cdd:PLN02644 375 VAGICNGGGGASAIVVELM 393
|
|
| PRK06690 |
PRK06690 |
acetyl-CoA C-acyltransferase; |
3-401 |
1.90e-65 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 180659 [Multi-domain] Cd Length: 361 Bit Score: 212.70 E-value: 1.90e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 3 EAYIIDAIRTPRGKgkKDGSLyevKPITLLTTLLNELQQRHQLDTSKVDDIVLGCVTpigDQGGDIAKTAAIAAGWNDDV 82
Cdd:PRK06690 2 RAVIVEAKRTPIGK--KNGML---KDYEVQQLAAPLLTFLSKGMEREIDDVILGNVV---GPGGNVARLSALEAGLGLHI 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 83 AGVQINRFCASGLEAVNMAAMKVRSGWEDLVVAGGVESMSRIPMGSdggpwaldpetnlKSSFVPQ-------GVGADLI 155
Cdd:PRK06690 74 PGVTIDRQCGAGLEAIRTACHFIQGGAGKCYIAGGVESTSTSPFQN-------------RARFSPEtigdpdmGVAAEYV 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 156 ATLDGYTREDVDTFAVNSQQKAAAAQANGYFDQSVVPVkdhSGVVilekDEFIKGNTTVEGLTK-LNPSFEMMGQMGfda 234
Cdd:PRK06690 141 AERYNITREMQDEYACLSYKRTLQALEKGYIHEEILSF---NGLL----DESIKKEMNYERIIKrTKPAFLHNGTVT--- 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 235 ialqkypeaqkinhvhhAGNSSGIVDGAAVVLLASEKAVKEQNLKPRAKVLATALVGTDPTIMLTGPAPAARKALEKAGL 314
Cdd:PRK06690 211 -----------------AGNSCGVNDGACAVLVMEEGQARKLGYKPVLRFVRSAVVGVDPNLPGTGPIFAVNKLLNEMNM 273
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 315 TIDDIDLFEVNEAFAAVVMRFINELNVPPEKVNVNGGAIALGHPLGATGAMILGTLLDELERQNKKRGLATLCVGGGMGI 394
Cdd:PRK06690 274 KVEDIDYFEINEAFASKVVACAKELQIPYEKLNVNGGAIALGHPYGASGAMLVTRLFYQAKREDMKYGIATLGIGGGIGL 353
|
....*..
gi 480057380 395 ATIIERV 401
Cdd:PRK06690 354 ALLFEKV 360
|
|
| PRK06954 |
PRK06954 |
acetyl-CoA C-acetyltransferase; |
41-399 |
1.15e-59 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180775 [Multi-domain] Cd Length: 397 Bit Score: 198.58 E-value: 1.15e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 41 QRHQLDTSKVDDIVLGCVTPIGdQGGDIAKTAAIAAGWNDDVAGVQINRFCASGLEAVNMAAMKVRSGWEDLVVAGGVES 120
Cdd:PRK06954 44 ERAGLKPEQIDEVVMGCVLPAG-QGQAPARQAALGAGLPLSVGCTTVNKMCGSGMRAAMFAHDMLVAGSVDVIVAGGMES 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 121 MSRIP--------------------MGSDGGPWALDpETNLKSSFvpqgvgADLIATLDGYTREDVDTFAVNSQQKAAAA 180
Cdd:PRK06954 123 MTNAPyllpkarggmrmghgqvldhMFLDGLEDAYD-KGRLMGTF------AEECAGEYGFTREAQDAFAIESLARAKRA 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 181 QANGYFDQSVVPVK--DHSGVVILEKDEFIKgNTTVEGLTKLNPSFEMMGQMGfdaialqkypeaqkinhvhhAGNSSGI 258
Cdd:PRK06954 196 NEDGSFAWEIAPVTvaGKKGDTVIDRDEQPF-KANPEKIPTLKPAFSKTGTVT--------------------AANSSSI 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 259 VDGAAVVLLASEKAVKEQNLKPRAKVLATALVGTDPTIMLTGPAPAARKALEKAGLTIDDIDLFEVNEAFAAVVMRFINE 338
Cdd:PRK06954 255 SDGAAALVMMRASTAKRLGLAPLARVVGHSTFAQAPSKFTTAPVGAIRKLFEKNGWRAAEVDLFEINEAFAVVTMAAMKE 334
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 480057380 339 LNVPPEKVNVNGGAIALGHPLGATGAMILGTLLDELERQNKKRGLATLCVGGGMGIATIIE 399
Cdd:PRK06954 335 HGLPHEKVNVNGGACALGHPIGASGARILVTLIGALRARGGKRGVASLCIGGGEATAMGIE 395
|
|
| Thiolase_C |
pfam02803 |
Thiolase, C-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl ... |
278-400 |
6.64e-58 |
|
Thiolase, C-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl synthase (pfam00109), and also chalcone synthase.
Pssm-ID: 397094 [Multi-domain] Cd Length: 123 Bit Score: 185.15 E-value: 6.64e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 278 LKPRAKVLATALVGTDPTIMLTGPAPAARKALEKAGLTIDDIDLFEVNEAFAAVVMRFINELNVPPEKVNVNGGAIALGH 357
Cdd:pfam02803 1 LKPLARIRSYATAGVDPAIMGIGPAYAIPKALKKAGLTVNDIDLFEINEAFAAQALAVAKDLGIDPEKVNVNGGAIALGH 80
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 480057380 358 PLGATGAMILGTLLDELERQNKKRGLATLCVGGGMGIATIIER 400
Cdd:pfam02803 81 PLGASGARILVTLLHELKRRGGKYGLASLCIGGGQGVAMIIER 123
|
|
| fadI |
PRK08963 |
3-ketoacyl-CoA thiolase; Reviewed |
6-400 |
1.59e-51 |
|
3-ketoacyl-CoA thiolase; Reviewed
Pssm-ID: 181597 [Multi-domain] Cd Length: 428 Bit Score: 178.25 E-value: 1.59e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 6 IIDAIRTPRGKGKKDgsLYEVKPITLLTTLLNELQQRHQLDTSKVDDIVLGCVTPIgDQGGDIAKTAAIAAGWNDDVAGV 85
Cdd:PRK08963 9 IVSGLRTPFAKQATA--FHGIPAVDLGKMVVGELLARSEIDPELIEQLVFGQVVQM-PEAPNIAREIVLGTGMNVHTDAY 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 86 QINRFCASGLEAVNMAAMKVRSGWEDLVVAGGVESMSRIPMG----------------SDGGPWALDPETNLKSsFVPQ- 148
Cdd:PRK08963 86 SVSRACATSFQAVANVAESIMAGTIDIGIAGGADSSSVLPIGvskklaralvdlnkarTLGQRLKLFSRLRLRD-LLPVp 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 149 ------------GVGADLIATLDGYTREDVDTFAVNSQQKAAAAQANGYFDQSVV-----PVKDHsgvviLEKDEFIKGN 211
Cdd:PRK08963 165 pavaeystglrmGDTAEQMAKTYGISREEQDALAHRSHQLAAQAWAEGKLDDEVMtahvpPYKQP-----LEEDNNIRGD 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 212 TTVEGLTKLNPSFEmmgqmgfdaialQKYPEAQkinhvhhAGNSSGIVDGAAVVLLASEKAVKEQNLKPRAKVLATALVG 291
Cdd:PRK08963 240 STLEDYAKLRPAFD------------RKHGTVT-------AANSTPLTDGAAAVLLMSESRAKALGLTPLGYLRSYAFAA 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 292 TDPTI-MLTGPAPAARKALEKAGLTIDDIDLFEVNEAFAAVVM---------RFINE-LN-------VPPEKVNVNGGAI 353
Cdd:PRK08963 301 IDVWQdMLLGPAYATPLALERAGLTLADLTLIDMHEAFAAQTLanlqmfaseRFAREkLGrsqaigeVDMSKFNVLGGSI 380
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 480057380 354 ALGHPLGATGA-MILGTlLDELERQNKKRGLATLCVGGGMGIATIIER 400
Cdd:PRK08963 381 AYGHPFAATGArMITQT-LHELRRRGGGLGLTTACAAGGLGAAMVLEV 427
|
|
| nondecarbox_cond_enzymes |
cd00826 |
nondecarboxylating condensing enzymes; In general, thiolases catalyze the reversible thiolytic ... |
40-399 |
2.66e-48 |
|
nondecarboxylating condensing enzymes; In general, thiolases catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. There are 2 functional different classes: thiolase-I (3-ketoacyl-CoA thiolase) and thiolase-II (acetoacetyl-CoA thiolase). Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several biosynthetic pathways.
Pssm-ID: 238422 [Multi-domain] Cd Length: 393 Bit Score: 168.83 E-value: 2.66e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 40 QQRHQLDTSKVDDIVLGCVTPIGdQGGDIAKTAAIAAGWNDDVAGVQINRFCASGLEAVNMAAMKVRSGWEDLVVAGGVE 119
Cdd:cd00826 35 LEPAGVAAGAVEEACLGQVLGAG-EGQNCAQQAAMHAGGLQEAPAIGMNNLCGSGLRALALAMQLIAGGDANCILAGGFE 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 120 SMSRIPMgSDGGPWALDPETNLKSSfvpqgvgadliatldgytREDVDTFAVNSQQKAAAAQANGYFDQSVVP--VKDHS 197
Cdd:cd00826 114 KMETSAE-NNAKEKHIDVLINKYGM------------------RACPDAFALAGQAGAEAAEKDGRFKDEFAKfgVKGRK 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 198 GVVILEKDEFIK--GNTTVEGLTKLNPSFEMMGQMGfdaialqkypeaqkinhvhhAGNSSGIVDGAAVVLLASEKAVKE 275
Cdd:cd00826 175 GDIHSDADEYIQfgDEASLDEIAKLRPAFDKEDFLT--------------------AGNACGLNDGAAAAILMSEAEAQK 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 276 QNLK-------PRAKVLATALVGTDPT----IMLTGPAPAARKALEKAGLTIDDIDLFEVNEAFAAVVMRFINELNVPPE 344
Cdd:cd00826 235 HGLQskareiqALEMITDMASTFEDKKvikmVGGDGPIEAARKALEKAGLGIGDLDLIEAHDAFAANACATNEALGLCPE 314
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 480057380 345 K------------------VNVNGGAIALGHPLGATGAMILGTLLDELERQNKKR-----GLATLCVGGGMGIATIIE 399
Cdd:cd00826 315 GqggalvdrgdntyggksiINPNGGAIAIGHPIGASGAAICAELCFELKGEAGKRqgagaGLALLCIGGGGGAAMCIE 392
|
|
| PRK09268 |
PRK09268 |
acetyl-CoA C-acetyltransferase; |
87-400 |
1.38e-45 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 236440 [Multi-domain] Cd Length: 427 Bit Score: 162.38 E-value: 1.38e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 87 INRFCASGLEAVNMAAMKVRSGWEDLVVAGGVESMSRIPMG-SDGGPWAL-------DPETNLK-------SSFVPQ--- 148
Cdd:PRK09268 89 LQQACGTGLEAAILVANKIALGQIDSGIAGGVDTTSDAPIAvNEGLRKILlelnrakTTGDRLKalgklrpKHLAPEipr 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 149 ----------GVGADLIATLDGYTREDVDTFAVNSQQKAAAAQANGYFDQSVVPVKDhsgvviLEKDEFIKGNTTVEGLT 218
Cdd:PRK09268 169 ngeprtglsmGEHAAITAKEWGISREAQDELAAASHQNLAAAYDRGFFDDLITPFLG------LTRDNNLRPDSSLEKLA 242
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 219 KLNPSFEmmgqmgfdaialqKYPEAQKInhvhhAGNSSGIVDGAAVVLLASEKAVKEQNLKPRAKVLA--TALV----GT 292
Cdd:PRK09268 243 KLKPVFG-------------KGGRATMT-----AGNSTPLTDGASVVLLASEEWAAEHGLPVLAYLVDaeTAAVdfvhGK 304
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 293 DPtiMLTGPAPAARKALEKAGLTIDDIDLFEVNEAFAAVVM---------RFINE---LNVP-----PEKVNVNGGAIAL 355
Cdd:PRK09268 305 EG--LLMAPAYAVPRLLARNGLTLQDFDFYEIHEAFASQVLatlkawedeEYCRErlgLDAPlgsidRSKLNVNGSSLAA 382
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 480057380 356 GHPLGATGAMILGTLLDELERQNKKRGLATLCVGGGMGIATIIER 400
Cdd:PRK09268 383 GHPFAATGGRIVATLAKLLAEKGSGRGLISICAAGGQGVTAILER 427
|
|
| Thiolase_N |
pfam00108 |
Thiolase, N-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl ... |
5-270 |
4.40e-41 |
|
Thiolase, N-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl synthase (pfam00109), and also chalcone synthase.
Pssm-ID: 459676 [Multi-domain] Cd Length: 260 Bit Score: 145.91 E-value: 4.40e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 5 YIIDAIRTPRGKGKkdGSLYEVKPITLLTTLLNELQQRHQLDTSKVDDIVLGCVTPIGdQGGDIAKTAAIAAGWNDDVAG 84
Cdd:pfam00108 2 VIVSAARTPFGSFG--GSLKDVSAVELGAEAIKAALERAGVDPEDVDEVIVGNVLQAG-EGQNPARQAALKAGIPDSAPA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 85 VQINRFCASGLEAVNMAAMKVRSGWEDLVVAGGVESMSRIPMG--SDGGPWALDPETNLKSSFVP-----------QGVG 151
Cdd:pfam00108 79 VTINKVCGSGLKAVYLAAQSIASGDADVVLAGGVESMSHAPYAlpTDARSGLKHGDEKKHDLLIPdgltdafngyhMGLT 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 152 ADLIATLDGYTREDVDTFAVNSQQKAAAAQANGYFDQSVVPV--KDHSGVVILEKDEFIKGNTTVEGLTKLNPSFEMMGQ 229
Cdd:pfam00108 159 AENVAKKYGISREEQDAFAVKSHQKAAAAPKAGKFKDEIVPVtvKGRKGKPTVDKDEGIRPPTTAEPLAKLKPAFDKEGT 238
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 480057380 230 MgfdaialqkypeaqkinhvhHAGNSSGIVDGAAVVLLASE 270
Cdd:pfam00108 239 V--------------------TAGNASPINDGAAAVLLMSE 259
|
|
| SCP-x_thiolase |
cd00829 |
Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; ... |
45-398 |
2.69e-22 |
|
Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; SCP-2 has multiple roles in intracellular lipid circulation and metabolism. The N-terminal presequence in the SCP-x isoform represents a peroxisomal 3-ketacyl-Coa thiolase specific for branched-chain acyl CoAs, which is proteolytically cleaved from the sterol carrier protein.
Pssm-ID: 238425 [Multi-domain] Cd Length: 375 Bit Score: 97.33 E-value: 2.69e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 45 LDTSKVDDIVLGCVTPiGDQGGDIAKTAAIAAGWnDDVAGVQINRFCASGLEAVNMAAMKVRSGWEDLVVAGGVESMSRI 124
Cdd:cd00829 33 LEPADIDAVVVGNAAG-GRFQSFPGALIAEYLGL-LGKPATRVEAAGASGSAAVRAAAAAIASGLADVVLVVGAEKMSDV 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 125 PMGSDGGPWALDPETNLKSSFVPQGVGAD--LIAT----LDGYTREDVDTFAVnsqqkaaaaqangyfdqsvvpvKDHS- 197
Cdd:cd00829 111 PTGDEAGGRASDLEWEGPEPPGGLTPPALyaLAARrymhRYGTTREDLAKVAV----------------------KNHRn 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 198 GVvilekdefikgnttvegltkLNPSfemmGQMGFDaIALQKYPEAQKINHVHHAGNSSGIVDGAAVVLLASEKAVKEQN 277
Cdd:cd00829 169 AA--------------------RNPY----AQFRKP-ITVEDVLNSRMIADPLRLLDCCPVSDGAAAVVLASEERARELT 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 278 LKPrAKVLATAlVGTDPT--------IMLTGPAPAARKALEKAGLTIDDIDLFEVNEAFAAVVMRFINEL---------- 339
Cdd:cd00829 224 DRP-VWILGVG-AASDTPslserddfLSLDAARLAARRAYKMAGITPDDIDVAELYDCFTIAELLALEDLgfcekgeggk 301
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 480057380 340 -----------NVPpekVNVNGGAIALGHPLGATGAMILGTLLDEL-----ERQNKKRGLATLCVGGGMGIATII 398
Cdd:cd00829 302 lvregdtaiggDLP---VNTSGGLLSKGHPLGATGLAQAVEAVRQLrgeagARQVPGARVGLAHNIGGTGSAAVV 373
|
|
| cond_enzymes |
cd00327 |
Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) ... |
252-398 |
6.36e-22 |
|
Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the production of polyketides, a diverse group of natural products.
Pssm-ID: 238201 [Multi-domain] Cd Length: 254 Bit Score: 94.05 E-value: 6.36e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 252 AGNSSGIVDGAAVVLLASEKAVKEQNLKPRAKVLATALVGTDPT----IMLTGPAPAARKALEKAGLTIDDIDLFEVNEA 327
Cdd:cd00327 94 GSEEFVFGDGAAAAVVESEEHALRRGAHPQAEIVSTAATFDGASmvpaVSGEGLARAARKALEGAGLTPSDIDYVEAHGT 173
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 328 FAAVVMRFINELNVPPEKV---NVNGGAIALGHPLGATGAMILGTLLDELERQNKKR-------GLATLCVGGGMGIATI 397
Cdd:cd00327 174 GTPIGDAVELALGLDPDGVrspAVSATLIMTGHPLGAAGLAILDELLLMLEHEFIPPtpreprtVLLLGFGLGGTNAAVV 253
|
.
gi 480057380 398 I 398
Cdd:cd00327 254 L 254
|
|
| PRK06064 |
PRK06064 |
thiolase domain-containing protein; |
91-363 |
8.06e-18 |
|
thiolase domain-containing protein;
Pssm-ID: 235688 [Multi-domain] Cd Length: 389 Bit Score: 84.18 E-value: 8.06e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 91 CASGLEAVNMAAMKVRSGWEDLVVAGGVESMSRIPMG--SDGGPWALDPETNLKSSFVPQGVGAdLIATLD----GYTRE 164
Cdd:PRK06064 85 CASGGAALRQAYLAVASGEADVVLAAGVEKMTDVPTPdaTEAIARAGDYEWEEFFGATFPGLYA-LIARRYmhkyGTTEE 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 165 DVDTFAVnsqqkaaaaqangyfdqsvvpvKDHSGVVILEKDEFiKGNTTVEglTKLNPSfemmgqmgfdaialqkyPEAQ 244
Cdd:PRK06064 164 DLALVAV----------------------KNHYNGSKNPYAQF-QKEITVE--QVLNSP-----------------PVAD 201
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 245 KINHVHhagnSSGIVDGAAVVLLASEKAVKEQNLKPrAKVLATAlVGTDpTI-------MLTGPAP--AARKALEKAGLT 315
Cdd:PRK06064 202 PLKLLD----CSPITDGAAAVILASEEKAKEYTDTP-VWIKASG-QASD-TIalhdrkdFTTLDAAvvAAEKAYKMAGIE 274
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 480057380 316 IDDIDLFEVNEAFAavvmrfINEL---------------------------NVPpekVNVNGGAIALGHPLGATG 363
Cdd:PRK06064 275 PKDIDVAEVHDCFT------IAEIlayedlgfakkgeggklaregqtyiggDIP---VNPSGGLKAKGHPVGATG 340
|
|
| PRK08256 |
PRK08256 |
lipid-transfer protein; Provisional |
260-363 |
4.60e-09 |
|
lipid-transfer protein; Provisional
Pssm-ID: 181327 [Multi-domain] Cd Length: 391 Bit Score: 57.60 E-value: 4.60e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 260 DGAAVVLLASEKAVKEQNLKPRAKVLATALVgTDPTIMLTGPAP-----------AARKALEKAGLTIDDIDLFEVNEAF 328
Cdd:PRK08256 215 CGAAAAIVCSEEFARKHGLDRAVEIVAQAMT-TDTPSTFDGRSMidlvgydmtraAAQQVYEQAGIGPEDIDVVELHDCF 293
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 480057380 329 AAvvmrfiNE------LNVPPE----------------KVNVN--GGAIALGHPLGATG 363
Cdd:PRK08256 294 SA------NElltyeaLGLCPEgeaekfiddgdntyggRWVVNpsGGLLSKGHPLGATG 346
|
|
| PRK12578 |
PRK12578 |
thiolase domain-containing protein; |
91-366 |
6.28e-08 |
|
thiolase domain-containing protein;
Pssm-ID: 183606 [Multi-domain] Cd Length: 385 Bit Score: 54.08 E-value: 6.28e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 91 CASGLEAVNMAAMKVRSGWEDLVVAGGVESMSRI------PMGSDGGPWALdpETNLKSSFVPQ--GVGADLIATLDGYT 162
Cdd:PRK12578 82 CATGLAASLTAYTAVASGLVDMAIAVGVDKMTEVdtstslAIGGRGGNYQW--EYHFYGTTFPTyyALYATRHMAVYGTT 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 163 REDVdtfavnsqqkaaaaqangyfdqSVVPVKDHSGVVILEKDEFIKgnttvegltklnpsfemmgqmgfdAIALQKYPE 242
Cdd:PRK12578 160 EEQM----------------------ALVSVKAHKYGAMNPKAHFQK------------------------PVTVEEVLK 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 243 AQKINHVHHAGNSSGIVDGAAVVLLASEKAVKEqnLKPRAKVLATAL-VGTDPTIM--------LTGPAPAARKALEKAG 313
Cdd:PRK12578 194 SRAISWPIKLLDSCPISDGSATAIFASEEKVKE--LKIDSPVWITGIgYANDYAYVarrgewvgFKATQLAARQAYNMAK 271
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 480057380 314 LTIDDIDLFEVNEAFA-AVVM--------------RFINELNVPPE-KVNVN--GGAIALGHPLGATG-AMI 366
Cdd:PRK12578 272 VTPNDIEVATVHDAFTiAEIMgyedlgftekgkggKFIEEGQSEKGgKVGVNlfGGLKAKGHPLGATGlSMI 343
|
|
| PTZ00455 |
PTZ00455 |
3-ketoacyl-CoA thiolase; Provisional |
256-363 |
7.33e-08 |
|
3-ketoacyl-CoA thiolase; Provisional
Pssm-ID: 240424 [Multi-domain] Cd Length: 438 Bit Score: 54.13 E-value: 7.33e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 256 SGIVDGAAVVLLASEKAVKEQNLKP------RAKVLATALVG-----TDPTIMLTGPApAARKALEKAGLTIDDIDLFEV 324
Cdd:PTZ00455 256 SQVSDGGAGLVLASEEGLQKMGLSPndsrlvEIKSLACASGNlyedpPDATRMFTSRA-AAQKALSMAGVKPSDLQVAEV 334
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 480057380 325 NEAFAAVVMRFINELNV--------------------PPekVNVNGGAIALGHPLGATG 363
Cdd:PTZ00455 335 HDCFTIAELLMYEALGIaeyghakdlirngatalegrIP--VNTGGGLLSFGHPVGATG 391
|
|
| PRK07516 |
PRK07516 |
thiolase domain-containing protein; |
256-401 |
7.79e-08 |
|
thiolase domain-containing protein;
Pssm-ID: 181013 [Multi-domain] Cd Length: 389 Bit Score: 53.80 E-value: 7.79e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 256 SGIVDGAAVVLLASEKAVKEqnLKPRAKVLATALVGT-------DPTIMlTGPAPAARKALEKAGLTIDDIDLFEVNEAF 328
Cdd:PRK07516 213 SLVSDGAAALVLADAETARA--LQRAVRFRARAHVNDflplsrrDPLAF-EGPRRAWQRALAQAGVTLDDLSFVETHDCF 289
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 329 --AAVVM-------------RFINELNVPPE---KVNVNGGAIALGHPLGATG-------AMILGTLLDELERQNKKRGL 383
Cdd:PRK07516 290 tiAELIEyeamglappgqgaRAIREGWTAKDgklPVNPSGGLKAKGHPIGATGvsmhvlaAMQLTGEAGGMQIPGAKLAG 369
|
170 180
....*....|....*....|.
gi 480057380 384 atLCVGGGMGIA---TIIERV 401
Cdd:PRK07516 370 --VFNMGGAAVAnyvSILERV 388
|
|
| PRK06289 |
PRK06289 |
acetyl-CoA acetyltransferase; Provisional |
256-367 |
2.45e-07 |
|
acetyl-CoA acetyltransferase; Provisional
Pssm-ID: 235771 [Multi-domain] Cd Length: 403 Bit Score: 52.38 E-value: 2.45e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 256 SGIVDGAAVVLLASEKAVKEQnlkPRAKVLA--------TALVGTDPTIMLTGPAP--------AARKALEKAGLTIDDI 319
Cdd:PRK06289 220 SQVTDGGAGVVLASDAYLRDY---ADARPIPrikgwghrTAPLGLEQKLDRSAGDPyvlphvrqAVLDAYRRAGVGLDDL 296
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 480057380 320 DLFEVNEAFAAVVMRFINELNV-PPEK-----------------VNVNGGAIALGHPLGATGA-MIL 367
Cdd:PRK06289 297 DGFEVHDCFTPSEYLAIDHIGLtGPGEswkaiengeiaiggrlpINPSGGLIGGGHPVGASGVrMLL 363
|
|
| PRK05952 |
PRK05952 |
beta-ketoacyl-ACP synthase; |
257-377 |
3.66e-06 |
|
beta-ketoacyl-ACP synthase;
Pssm-ID: 235653 [Multi-domain] Cd Length: 381 Bit Score: 48.51 E-value: 3.66e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 257 GIV--DGAAVVLLASEKAVKEQNLKPRAKVL-----ATALVGTDPTIMLTGPAPAARKALEKAGLTIDDIDLF------- 322
Cdd:PRK05952 205 GLVlgEGGAILVLESAELAQKRGAKIYGQILgfgltCDAYHMSAPEPDGKSAIAAIQQCLARSGLTPEDIDYIhahgtat 284
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 480057380 323 EVNEAFAAVVMRfinelNVPPEKVNVNGGAIALGHPLGATGAMILGTLLDELERQ 377
Cdd:PRK05952 285 RLNDQREANLIQ-----ALFPHRVAVSSTKGATGHTLGASGALGVAFSLLALRHQ 334
|
|
| FabH |
COG0332 |
3-oxoacyl-[acyl-carrier-protein] synthase III [Lipid transport and metabolism]; 3-oxoacyl- ... |
302-392 |
7.04e-06 |
|
3-oxoacyl-[acyl-carrier-protein] synthase III [Lipid transport and metabolism]; 3-oxoacyl-[acyl-carrier-protein] synthase III is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 440101 [Multi-domain] Cd Length: 323 Bit Score: 47.41 E-value: 7.04e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 302 APAARKALEKAGLTIDDIDLF---EVNEAFAAVVMRfinELNVPPEKVNVNggaIA-LGHplgaTGAMILGTLLDELERQ 377
Cdd:COG0332 227 PEVIREALEKAGLTLDDIDWFiphQANLRIIEAVAK---RLGLPEEKVVVN---IDrYGN----TSAASIPLALDEALRE 296
|
90
....*....|....*...
gi 480057380 378 NK-KRG--LATLCVGGGM 392
Cdd:COG0332 297 GRiKPGdlVLLAGFGAGL 314
|
|
| PRK06365 |
PRK06365 |
thiolase domain-containing protein; |
260-399 |
1.23e-05 |
|
thiolase domain-containing protein;
Pssm-ID: 235785 [Multi-domain] Cd Length: 430 Bit Score: 47.21 E-value: 1.23e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 260 DGAAVVLLASEKAVKEQNLKP-RAKVLATALVGTDPTIMLTGPAP--------------------------AARKALEKA 312
Cdd:PRK06365 227 DGAACAILASEDKAFEITDKPvLIKAIGTGSDTLRLADRPFGEVPllpnespddykdlrypgvhsfragrmAAKEAYEMA 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 313 GLT--IDDIDLFEVNEAFAAVVMRFINELNVPPE------------------KVNVNGGAIALGHPLGATGAM------- 365
Cdd:PRK06365 307 GITdpLNDLDLIELHDAYTSSEIQTYEDLGLCKYgeggqfiesgkpelpgklPVNPSGGLLAAGHAVGATGIMqavfmfw 386
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 480057380 366 -ILGTL-----LDELERQNKKRGLATLCVGGGMGI-ATIIE 399
Cdd:PRK06365 387 qLQGRIkkhfhDDYLQVKNAKRGLIHSHAGTGTYVtVTILE 427
|
|
| PRK06066 |
PRK06066 |
thiolase domain-containing protein; |
92-391 |
1.62e-05 |
|
thiolase domain-containing protein;
Pssm-ID: 180380 [Multi-domain] Cd Length: 385 Bit Score: 46.67 E-value: 1.62e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 92 ASGLEAVNMAAMKVRSGWEDLVVaggVESMSR---IPMGSDGGPWALDP----ETNLKSSFVPQGVGADLIATLDGYTRE 164
Cdd:PRK06066 86 GDGLQGLAHAVMHINSGLANVVV---VEAHSKpsdILTFSDVVKFAMDPiyvrPIGPPNPHFIAGLDAVKFMSRKGITRE 162
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 165 DVDTFAVNSQQkaaaaqaNGYFDqsvvPVKDHSGVVILekDEFIKGNTTVEGLTKLNpsfemmgqmgfdaIAlqkypeaq 244
Cdd:PRK06066 163 DLALVVEKNKK-------AGLSN----PRASYASNISL--EDVLSSEYVVYPLTELD-------------IA-------- 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 245 kinhvhhagnssGIVDGAAVVLLASEKAVKEQNLKP---RAKVLATALVGTDptIMLTGPAPAARKALEKA----GLT-- 315
Cdd:PRK06066 209 ------------PFVDGAIVVVLASEEVAKKLTDDPvwiKGIGWSTESSNLE--TAELGKANYMRIAADMAykmaGIEsp 274
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 316 IDDIDLFEVNEAFAAVVMRFINELNVPPE------------------KVNVNGGAIALGHPLGATGamiLGTLLDELERQ 377
Cdd:PRK06066 275 RKEVDAAEVDDRYSYKELQHIEALRLSEEpekdsllregnfdpqgelPVNPSGGHLAKGVPLEASG---LSLLLDAVEYL 351
|
330
....*....|....
gi 480057380 378 nkkRGLATLCVGGG 391
Cdd:PRK06066 352 ---RGEAGARQGKA 362
|
|
| KAS_III |
cd00830 |
Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty ... |
302-398 |
5.75e-05 |
|
Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP. KASIII initiates this process by specifically using acetyl-CoA over acyl-CoA.
Pssm-ID: 238426 [Multi-domain] Cd Length: 320 Bit Score: 44.84 E-value: 5.75e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 302 APAARKALEKAGLTIDDIDLF-------EVNEAFAAvvmrfinELNVPPEKVNVNggaialGHPLGATGAMILGTLLDEL 374
Cdd:cd00830 226 PESIEEALEKAGLTPDDIDWFvphqanlRIIEAVAK-------RLGLPEEKVVVN------LDRYGNTSAASIPLALDEA 292
|
90 100
....*....|....*....|....*..
gi 480057380 375 ERQNK-KRG-LATLC-VGGGMGIATII 398
Cdd:cd00830 293 IEEGKlKKGdLVLLLgFGAGLTWGAAL 319
|
|
| decarbox_cond_enzymes |
cd00825 |
decarboxylating condensing enzymes; Family of enzymes that catalyze the formation of a new ... |
260-375 |
1.13e-04 |
|
decarboxylating condensing enzymes; Family of enzymes that catalyze the formation of a new carbon-carbon bond by a decarboxylating Claisen-like condensation reaction. Members are involved in the synthesis of fatty acids and polyketides, a diverse group of natural products. Both pathways are an iterative series of additions of small carbon units, usually acetate, to a nascent acyl group. There are 2 classes of decarboxylating condensing enzymes, which can be distinguished by sequence similarity, type of active site residues and type of primer units (acetyl CoA or acyl carrier protein (ACP) linked units).
Pssm-ID: 238421 [Multi-domain] Cd Length: 332 Bit Score: 43.78 E-value: 1.13e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 260 DGAAVVLLASEKAVKEQNLKPRAKVLATALvGTDPTIM------LTGPAPAARKALEKAGLTIDDIDLFEVNEAFAAVVM 333
Cdd:cd00825 161 DGAGALVVEELEHALARGAHIYAEIVGTAA-TIDGAGMgafapsAEGLARAAKEALAVAGLTVWDIDYLVAHGTGTPIGD 239
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 480057380 334 RFINELNVP---PEKVNVNGGAIALGHPLGATGAMILGTLLDELE 375
Cdd:cd00825 240 VKELKLLRSefgDKSPAVSATKAMTGNLSSAAVVLAVDEAVLMLE 284
|
|
| ketoacyl-synt |
pfam00109 |
Beta-ketoacyl synthase, N-terminal domain; The structure of beta-ketoacyl synthase is similar ... |
91-132 |
2.95e-04 |
|
Beta-ketoacyl synthase, N-terminal domain; The structure of beta-ketoacyl synthase is similar to that of the thiolase family (pfam00108) and also chalcone synthase. The active site of beta-ketoacyl synthase is located between the N and C-terminal domains. The N-terminal domain contains most of the structures involved in dimer formation and also the active site cysteine.
Pssm-ID: 425468 [Multi-domain] Cd Length: 251 Bit Score: 42.24 E-value: 2.95e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 480057380 91 CASGLEAVNMAAMKVRSGWEDLVVAGGVESM---------SRIPMGSDGGP 132
Cdd:pfam00109 173 CSSSLVAIHAAVQSIRSGEADVALAGGVNLLltplgfagfSAAGMLSPDGP 223
|
|
| ACP_syn_III_C |
pfam08541 |
3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; This domain is found on ... |
309-398 |
5.40e-04 |
|
3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; This domain is found on 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III EC:2.3.1.41, the enzyme responsible for initiating the chain of reactions of the fatty acid synthase in plants and bacteria.
Pssm-ID: 430060 Cd Length: 90 Bit Score: 38.64 E-value: 5.40e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 309 LEKAGLTIDDIDLFEVNEAFAAVVMRFINELNVPPEKVNVNggaiaLGHpLGATGAMILGTLLDELERQNK-KRG-LATL 386
Cdd:pfam08541 1 LEKAGLTPEDIDWFVPHQANLRIIDAVAKRLGLPPEKVVVN-----LDE-YGNTSAASIPLALDEAVEEGKlKPGdLVLL 74
|
90
....*....|...
gi 480057380 387 C-VGGGMGIATII 398
Cdd:pfam08541 75 VgFGAGLTWGAAL 87
|
|
| PRK07103 |
PRK07103 |
polyketide beta-ketoacyl:acyl carrier protein synthase; Validated |
254-320 |
7.61e-04 |
|
polyketide beta-ketoacyl:acyl carrier protein synthase; Validated
Pssm-ID: 180839 [Multi-domain] Cd Length: 410 Bit Score: 41.56 E-value: 7.61e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 480057380 254 NSSGIVDG--AAVVLLASEKAVKEQNLKPRAKVLATALV-----GTDPTimLTGPAPAARKALEKAGLTIDDID 320
Cdd:PRK07103 231 DRDGFIYGeaCGAVVLESAESARRRGARPYAKLLGWSMRldanrGPDPS--LEGEMRVIRAALRRAGLGPEDID 302
|
|
| init_cond_enzymes |
cd00827 |
"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, ... |
39-131 |
8.69e-04 |
|
"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are characterized by the utlization of CoA substrate primers, as well as the nature of their active site residues.
Pssm-ID: 238423 [Multi-domain] Cd Length: 324 Bit Score: 40.88 E-value: 8.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 39 LQQRHQLDTSKVDDIVLGCVTPIgDQGGDIAKTAAIAAGwNDDVAGVQINRFCASGLEAVNMAAMKVRSG-WED-LVVAG 116
Cdd:cd00827 59 ALERAGIDPDDIGLLIVATESPI-DKGKSAATYLAELLG-LTNAEAFDLKQACYGGTAALQLAANLVESGpWRYaLVVAS 136
|
90 100
....*....|....*....|.
gi 480057380 117 GV------ESMSRIPMGSDGG 131
Cdd:cd00827 137 DIasylldEGSALEPTLGDGA 157
|
|
| FabB |
COG0304 |
3-oxoacyl-(acyl-carrier-protein) synthase [Lipid transport and metabolism, Secondary ... |
256-365 |
9.75e-04 |
|
3-oxoacyl-(acyl-carrier-protein) synthase [Lipid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]; 3-oxoacyl-(acyl-carrier-protein) synthase is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 440073 [Multi-domain] Cd Length: 409 Bit Score: 41.23 E-value: 9.75e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 256 SGIV--DGAAVVLLASEKAVKEQNLKPRAKVL-------ATALVGTDPTimLTGPAPAARKALEKAGLTIDDIDLfeVN- 325
Cdd:COG0304 225 DGFVlgEGAGVLVLEELEHAKARGAKIYAEVVgygassdAYHITAPAPD--GEGAARAMRAALKDAGLSPEDIDY--INa 300
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 480057380 326 -------------EAFAAVvmrFINELNVPPekVNVNGGAIalGHPLGATGAM 365
Cdd:COG0304 301 hgtstplgdaaetKAIKRV---FGDHAYKVP--VSSTKSMT--GHLLGAAGAI 346
|
|
| PRK06158 |
PRK06158 |
thiolase; Provisional |
261-401 |
1.02e-03 |
|
thiolase; Provisional
Pssm-ID: 180434 [Multi-domain] Cd Length: 384 Bit Score: 40.78 E-value: 1.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 261 GAAVVLLASEKAvkeQNL-KPRAKVLATAL------VGTDPTIMLTGPAPAARKALEKAGLTIDDIDLFEVNEAFAAVVM 333
Cdd:PRK06158 212 AGAVVMVRADRA---RDLpRPPVYVLGAAAatwhrqISSMPDLTVTAAAESGPRAFAMAGLTPADIDVVELYDAFTINTI 288
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 480057380 334 RFINELNVPPEKVN---VNGGAIALGhplgatGAMILGTlldelerqnKKRGLAtlCVGGGM-GIATIIERV 401
Cdd:PRK06158 289 LFLEDLGFCAKGEGgafVEGGRIAPG------GRLPVNT---------NGGGLS--CVHPGMyGLFLLIEAV 343
|
|
| KAS_I_II |
cd00834 |
Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible ... |
256-365 |
1.38e-03 |
|
Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP.
Pssm-ID: 238430 [Multi-domain] Cd Length: 406 Bit Score: 40.60 E-value: 1.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 256 SGIV--DGAAVVLLASEKAVKEQNLKPRAKVLATALVG-----TDPTIMLTGPAPAARKALEKAGLTIDDIDLfeVN--- 325
Cdd:cd00834 225 DGFVlgEGAGVLVLESLEHAKARGAKIYAEILGYGASSdayhiTAPDPDGEGAARAMRAALADAGLSPEDIDY--INahg 302
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 480057380 326 -----------EAFAAVvmrFINELNVPPekVNVNGGAIalGHPLGATGAM 365
Cdd:cd00834 303 tstplndaaesKAIKRV---FGEHAKKVP--VSSTKSMT--GHLLGAAGAV 346
|
|
| PRK08313 |
PRK08313 |
thiolase domain-containing protein; |
260-366 |
1.50e-03 |
|
thiolase domain-containing protein;
Pssm-ID: 181378 [Multi-domain] Cd Length: 386 Bit Score: 40.48 E-value: 1.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 260 DGAAVVLLASEKAVKEQNLKPRAKVLATALVgTDPTIML-------TGPAPAARKALEKAGLT--IDDIDLFEVNEAFAA 330
Cdd:PRK08313 210 DGACAVVIGDEEAADAAAGRPVAWIHGTAMR-TEPLAFAgrdqvnpQAGRDAAAALWKAAGITdpRDEIDVAEIYVPFSW 288
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 480057380 331 VVMRFINELNVPPE------------------KVNVNGGAIAlGHPLGATGaMI 366
Cdd:PRK08313 289 FEPMWLENLGFAPEgegwklteagetaiggrlPVNPSGGVLS-SNPIGASG-MI 340
|
|
| KAS_I_II |
cd00834 |
Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible ... |
91-122 |
1.51e-03 |
|
Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP.
Pssm-ID: 238430 [Multi-domain] Cd Length: 406 Bit Score: 40.60 E-value: 1.51e-03
10 20 30
....*....|....*....|....*....|..
gi 480057380 91 CASGLEAVNMAAMKVRSGWEDLVVAGGVESMS 122
Cdd:cd00834 161 CASGAHAIGDAARLIRLGRADVVIAGGAEALI 192
|
|
| PRK08257 |
PRK08257 |
acetyl-CoA acetyltransferase; Validated |
259-344 |
3.18e-03 |
|
acetyl-CoA acetyltransferase; Validated
Pssm-ID: 236204 [Multi-domain] Cd Length: 498 Bit Score: 39.51 E-value: 3.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 259 VD-GAAVVLLASEKA----VKEQNL----------KPRAkVLATALVGTDPTIMLtgpapAARKALEKAGLTIDDIDLFE 323
Cdd:PRK08257 243 VDqGAAVLLTSVAKArrlgVPEDRWvylhggadahDPYD-ILERPDLHRSPAIRA-----AGRRALALAGLGIDDIDAFD 316
|
90 100
....*....|....*....|.
gi 480057380 324 VNEAFAAVVMRFINELNVPPE 344
Cdd:PRK08257 317 LYSCFPSAVQVAARELGLDLD 337
|
|
| FabB |
COG0304 |
3-oxoacyl-(acyl-carrier-protein) synthase [Lipid transport and metabolism, Secondary ... |
91-128 |
3.33e-03 |
|
3-oxoacyl-(acyl-carrier-protein) synthase [Lipid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]; 3-oxoacyl-(acyl-carrier-protein) synthase is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 440073 [Multi-domain] Cd Length: 409 Bit Score: 39.31 E-value: 3.33e-03
10 20 30
....*....|....*....|....*....|....*....
gi 480057380 91 CASGLEAVNMAAMKVRSGWEDLVVAGGVESM-SRIPMGS 128
Cdd:COG0304 161 CASGAHAIGEAYRLIRRGRADVMIAGGAEAAiTPLGLAG 199
|
|
| PRK06157 |
PRK06157 |
acetyl-CoA acetyltransferase; Validated |
45-384 |
3.37e-03 |
|
acetyl-CoA acetyltransferase; Validated
Pssm-ID: 180433 [Multi-domain] Cd Length: 398 Bit Score: 39.24 E-value: 3.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 45 LDTSKVDDIVLGcvTPIGDQGGDIAKTAAIAAGWNDDVAGVQINRFCASGLEAVNMAAMKVRSGWEDLVVAGGVESM--- 121
Cdd:PRK06157 44 IEPKDIDAAWFG--THYDEIGSGKSGTPLSRALRLPNIPVTRVENFCATGSEAFRGAVYAVASGAYDIALALGVEKLkdt 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 122 --SRIPMGSDGGP-WALDPETNLKSSFVpQGVGAdlIATLDGYTREDVDTFAVNsqqkaaaaqangyfdqsvVPVKDHSG 198
Cdd:PRK06157 122 gyGGLPVANPGTLaDMTMPNVTAPGNFA-QLASA--YAAKYGVSREDLKRAMAH------------------VSVKSHAN 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 199 VVILEKDEFIKgNTTVEGLTKlnpSFEMMGQMG-FDAialqkypeaqkinhvhhagnsSGIVDGAAVVLLASEKAVKEQN 277
Cdd:PRK06157 181 GARNPKAHLRK-AVTEEQVLK---APMIAGPLGlFDC---------------------CGVSDGAAAAIVTTPEIARALG 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 278 LKPRAKVLATALV----------GTDPTIMLTGPApAARKALEKAGLT--IDDIDLFEVNEAFAAVVMRFINELNVPPE- 344
Cdd:PRK06157 236 KKDPVYVKALQLAvsngwelqynGWDGSYFPTTRI-AARKAYREAGITdpREELSMAEVHDCFSITELVTMEDLGLSERg 314
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 480057380 345 -----------------KVNVNGGAIALGHPLGATGAMILGTLLDEL-----ERQ--NKKRGLA 384
Cdd:PRK06157 315 qawrdvldgffdadgglPCQIDGGLKCFGHPIGASGLRMLYEMYLQLlgragERQlkNPRLALT 378
|
|
| PRK09352 |
PRK09352 |
beta-ketoacyl-ACP synthase 3; |
302-391 |
3.71e-03 |
|
beta-ketoacyl-ACP synthase 3;
Pssm-ID: 236475 [Multi-domain] Cd Length: 319 Bit Score: 38.90 E-value: 3.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 480057380 302 APAARKALEKAGLTIDDIDLF-------EVNEAFAavvmrfiNELNVPPEKVNVNggaiaLGHpLGATGAMILGTLLDEL 374
Cdd:PRK09352 222 AKVAREALEAAGLTPEDIDWLvphqanlRIIDATA-------KKLGLPMEKVVVT-----VDK-YGNTSAASIPLALDEA 288
|
90 100
....*....|....*....|
gi 480057380 375 ERQNK-KRG--LATLCVGGG 391
Cdd:PRK09352 289 VRDGRiKRGdlVLLEGFGGG 308
|
|
| |
