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Conserved domains on  [gi|512048696|gb|EPD48352|]
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hypothetical protein HMPREF1206_00605 [Corynebacterium sp. HFH0082]

Protein Classification

ABC transporter permease( domain architecture ID 11426318)

ABC transporter permease is the transmembrane subunit found in a periplasmic binding protein (PBP)-dependent ABC transport system, which may be involved in the transport of one or more from a variety of substrates including sugars, ions, amino acids, and peptides, among others

Gene Ontology:  GO:0140359|GO:0042626
TCDB:  3.A.1

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
SalY COG0577
ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms];
193-475 3.14e-32

ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms];


:

Pssm-ID: 440342 [Multi-domain]  Cd Length: 339  Bit Score: 125.78  E-value: 3.14e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512048696 193 LIAADPGWFDIYARTIVQGRRLEDADGQRLMNPVVVNDQFYESLGNPALADHPTFRLketGNTTFTVVGVYkslgswdap 272
Cdd:COG0577  110 VLGVDPDYFRVLGIPLLAGRFFTAADDLGAPPVVVIGEALARRLFGGEDPVGKTIRL---NGRPFTVVGVV--------- 177
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512048696 273 sivthydsflnagyegqvgepqllvatpeesakenQKALHNIFqAELGPSWKVNTSLSEKDTQISQEMNNTITTALGIIG 352
Cdd:COG0577  178 -----------------------------------EAELRALL-RRRDPGDDFEVQTLDEILAALYGVLRTLTLLLGAIA 221
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512048696 353 GIVIALGALGLLTVSIVTIGHRVREIGIRRAMGASAGRIFISVFLESIVATTVAGVVGVIASIITVKQlpLDKMLALPle 432
Cdd:COG0577  222 GLALLVACIGIMNLMLASVTERTREIGIRKALGASRRDILRQFLTEALLLALLGGLLGLLLALLLLRL--LAALLGLP-- 297
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 512048696 433 tgaVAYPVTAAVIGVLVATFVGALAGIIPATIAVRVKPIDAIR 475
Cdd:COG0577  298 ---VSLDPWVLLLALALSLLVGLLAGLYPARRAARLDPVEALR 337
 
Name Accession Description Interval E-value
SalY COG0577
ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms];
193-475 3.14e-32

ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms];


Pssm-ID: 440342 [Multi-domain]  Cd Length: 339  Bit Score: 125.78  E-value: 3.14e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512048696 193 LIAADPGWFDIYARTIVQGRRLEDADGQRLMNPVVVNDQFYESLGNPALADHPTFRLketGNTTFTVVGVYkslgswdap 272
Cdd:COG0577  110 VLGVDPDYFRVLGIPLLAGRFFTAADDLGAPPVVVIGEALARRLFGGEDPVGKTIRL---NGRPFTVVGVV--------- 177
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512048696 273 sivthydsflnagyegqvgepqllvatpeesakenQKALHNIFqAELGPSWKVNTSLSEKDTQISQEMNNTITTALGIIG 352
Cdd:COG0577  178 -----------------------------------EAELRALL-RRRDPGDDFEVQTLDEILAALYGVLRTLTLLLGAIA 221
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512048696 353 GIVIALGALGLLTVSIVTIGHRVREIGIRRAMGASAGRIFISVFLESIVATTVAGVVGVIASIITVKQlpLDKMLALPle 432
Cdd:COG0577  222 GLALLVACIGIMNLMLASVTERTREIGIRKALGASRRDILRQFLTEALLLALLGGLLGLLLALLLLRL--LAALLGLP-- 297
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 512048696 433 tgaVAYPVTAAVIGVLVATFVGALAGIIPATIAVRVKPIDAIR 475
Cdd:COG0577  298 ---VSLDPWVLLLALALSLLVGLLAGLYPARRAARLDPVEALR 337
ADOP TIGR03434
Acidobacterial duplicated orphan permease; Members of this protein family are found, so far, ...
195-475 2.18e-15

Acidobacterial duplicated orphan permease; Members of this protein family are found, so far, only in three species of Acidobacteria, namely Acidobacteria bacterium Ellin345, Acidobacterium capsulatum ATCC 51196, and Solibacter usitatus Ellin6076, where they form large paralogous families. Each protein contains two copies of a domain called the efflux ABC transporter permease protein (pfam02687). However, unlike other members of that family (including LolC, FtsX, and MacB), genes for these proteins are essentially never found fused or adjacent to ABC transporter ATP-binding protein (pfam00005) genes. We name this family ADOP, for Acidobacterial Duplicated Orphan Permease, to reflect the restricted lineage, internal duplication, lack of associated ATP-binding cassette proteins, and permease homology. The function is unknown.


Pssm-ID: 274576 [Multi-domain]  Cd Length: 803  Bit Score: 78.71  E-value: 2.18e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512048696  195 AADPGWFDIYARTIVQGRRLEDADGQRLMNPVVVNDQFYESL--GNPALADHptFRLKETGNTTFTVVGVYKSL--GSWD 270
Cdd:TIGR03434 531 RVSPGYFETMGIPLLRGRDFTERDTAGSPPVAIVNEAFARRYfpGEDPIGKR--IRLGGDDGPWFEIVGVVGDVryAGLD 608
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512048696  271 APSIVTHYDSFLNAGYegqvGEPQLLVAT---PEESAKENQKALHNIFqAELGPSWkVNTSLSEKDTQISQEmnNTITTA 347
Cdd:TIGR03434 609 EPPRPEVYLPYAQSPD----RGMTLVVRTagdPAALAAAVRRAVRAID-PNLPVYD-VRTMEEQVDRSLAQE--RFLALL 680
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512048696  348 LGIIGGIVIALGALGLLTVSIVTIGHRVREIGIRRAMGASAGRIFISVFLESIVATTVAGVVGVIASIITVKqlPLDKML 427
Cdd:TIGR03434 681 LGLFAALALLLAAIGLYGVLAYSVAQRTREIGIRMALGAQRGDVLRLVLRQGLRLAAAGLAIGLAAALALAR--LLASLL 758
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 512048696  428 AlpletGAVAY-PVT-AAVIGVLVAtfVGALAGIIPATIAVRVKPIDAIR 475
Cdd:TIGR03434 759 F-----GVSPTdPLTfAAVAALLLA--VALLACYLPARRAARVDPMIALR 801
FtsX pfam02687
FtsX-like permease family; This is a family of predicted permeases and hypothetical ...
349-470 7.68e-12

FtsX-like permease family; This is a family of predicted permeases and hypothetical transmembrane proteins. Swiss:P57382 has been shown to transport lipids targeted to the outer membrane across the inner membrane. Both Swiss:P57382 and Swiss:O54500 have been shown to require ATP. This region contains three transmembrane helices.


Pssm-ID: 460652 [Multi-domain]  Cd Length: 120  Bit Score: 62.27  E-value: 7.68e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512048696  349 GIIGGIVIALGALGLLTVSIVTIGHRVREIGIRRAMGASAGRIFISVFLESIVATTVAGVVGVIASIITVKqlPLDKMLA 428
Cdd:pfam02687   1 ILFSLLILLLAVLIILLLLSISISERRREIGILRALGASRKQIFKLLLLEALLIGLIGLVIGLLLGLLLAK--LIAILLY 78
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 512048696  429 LPLETGAVAYPVTAAVIGVLVATFVGALAGIIPATIAVRVKP 470
Cdd:pfam02687  79 SSGISLPILVPPLSILIALLLALLIALLASLLPALRIRKINP 120
PRK10535 PRK10535
macrolide ABC transporter ATP-binding protein/permease MacB;
253-474 1.17e-11

macrolide ABC transporter ATP-binding protein/permease MacB;


Pssm-ID: 182528 [Multi-domain]  Cd Length: 648  Bit Score: 67.06  E-value: 1.17e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512048696 253 GNTTFTVVGVY----------KSLGSWDAPSIVTHY---DSFLNA-------GYEGQVGEPQLLVATPEESAKENqkalh 312
Cdd:PRK10535 427 GNMPATVIGVAeekqsmfgssKVLRVWLPYSTMSGRvmgQSWLNSitvrvkeGYDSAEAEQQLTRLLTLRHGKKD----- 501
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512048696 313 nIFqaelgpSWKVNTSL--SEKDTQisqemnnTITTALGIIGGIVIALGALGLLTVSIVTIGHRVREIGIRRAMGASAGR 390
Cdd:PRK10535 502 -FF------TWNMDSVLktAEKTTR-------TLQLFLTLVAVISLVVGGIGVMNIMLVSVTERTREIGIRMAVGARASD 567
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512048696 391 IFISVFLESIVATTVAGVVGVIASIItvkqlpLDKMLALPLETGAVAYPVTAAVIGVLVATFVGALAGIIPATIAVRVKP 470
Cdd:PRK10535 568 VLQQFLIEAVLVCLVGGALGITLSLL------IAFTLQLFLPGWEIGFSPLALLSAFLCSTVTGILFGWLPARNAARLDP 641

                 ....
gi 512048696 471 IDAI 474
Cdd:PRK10535 642 VDAL 645
 
Name Accession Description Interval E-value
SalY COG0577
ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms];
193-475 3.14e-32

ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms];


Pssm-ID: 440342 [Multi-domain]  Cd Length: 339  Bit Score: 125.78  E-value: 3.14e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512048696 193 LIAADPGWFDIYARTIVQGRRLEDADGQRLMNPVVVNDQFYESLGNPALADHPTFRLketGNTTFTVVGVYkslgswdap 272
Cdd:COG0577  110 VLGVDPDYFRVLGIPLLAGRFFTAADDLGAPPVVVIGEALARRLFGGEDPVGKTIRL---NGRPFTVVGVV--------- 177
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512048696 273 sivthydsflnagyegqvgepqllvatpeesakenQKALHNIFqAELGPSWKVNTSLSEKDTQISQEMNNTITTALGIIG 352
Cdd:COG0577  178 -----------------------------------EAELRALL-RRRDPGDDFEVQTLDEILAALYGVLRTLTLLLGAIA 221
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512048696 353 GIVIALGALGLLTVSIVTIGHRVREIGIRRAMGASAGRIFISVFLESIVATTVAGVVGVIASIITVKQlpLDKMLALPle 432
Cdd:COG0577  222 GLALLVACIGIMNLMLASVTERTREIGIRKALGASRRDILRQFLTEALLLALLGGLLGLLLALLLLRL--LAALLGLP-- 297
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 512048696 433 tgaVAYPVTAAVIGVLVATFVGALAGIIPATIAVRVKPIDAIR 475
Cdd:COG0577  298 ---VSLDPWVLLLALALSLLVGLLAGLYPARRAARLDPVEALR 337
LolE COG4591
ABC-type transport system involved in lipoprotein release, permease component LolC [Cell wall ...
254-475 4.40e-26

ABC-type transport system involved in lipoprotein release, permease component LolC [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443648 [Multi-domain]  Cd Length: 283  Bit Score: 107.31  E-value: 4.40e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512048696 254 NTTFTVVGVYKS-LGSWDAPSIVTHYDSFLNA-GYEGQVGEPQLLVATPEESAKenqkalhniFQAELGPSWKVNTSLSE 331
Cdd:COG4591   65 TRRFTVVGIFESgGYELDGSLVYVPLETAQELlGLGDQVSGILVKLKDGADAEA---------VAAALEAALPGLEVKTW 135
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512048696 332 KDTQISQ-EMNNTITTALGIIGGIVIALGALGLLTVSIVTIGHRVREIGIRRAMGASAGRIFISVFLESIVATTVAGVVG 410
Cdd:COG4591  136 RELNAALfSALKTEKLILLLILLLILLVAAFNIVNTLLMSVLERTREIGILKALGASRRQIRRIFLLEGLLLGLIGGLLG 215
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 512048696 411 VIASIITVKQL-PLDKMLALPLETGAVAYPVTAAVIGVLVATFVGALAGIIPATIAVRVKPIDAIR 475
Cdd:COG4591  216 LLLGLLLALLLnALLGILLPFIFALPVSLSPSDVLLALLLALLISLLASLYPARRAARLDPVEALR 281
ADOP TIGR03434
Acidobacterial duplicated orphan permease; Members of this protein family are found, so far, ...
195-475 2.18e-15

Acidobacterial duplicated orphan permease; Members of this protein family are found, so far, only in three species of Acidobacteria, namely Acidobacteria bacterium Ellin345, Acidobacterium capsulatum ATCC 51196, and Solibacter usitatus Ellin6076, where they form large paralogous families. Each protein contains two copies of a domain called the efflux ABC transporter permease protein (pfam02687). However, unlike other members of that family (including LolC, FtsX, and MacB), genes for these proteins are essentially never found fused or adjacent to ABC transporter ATP-binding protein (pfam00005) genes. We name this family ADOP, for Acidobacterial Duplicated Orphan Permease, to reflect the restricted lineage, internal duplication, lack of associated ATP-binding cassette proteins, and permease homology. The function is unknown.


Pssm-ID: 274576 [Multi-domain]  Cd Length: 803  Bit Score: 78.71  E-value: 2.18e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512048696  195 AADPGWFDIYARTIVQGRRLEDADGQRLMNPVVVNDQFYESL--GNPALADHptFRLKETGNTTFTVVGVYKSL--GSWD 270
Cdd:TIGR03434 531 RVSPGYFETMGIPLLRGRDFTERDTAGSPPVAIVNEAFARRYfpGEDPIGKR--IRLGGDDGPWFEIVGVVGDVryAGLD 608
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512048696  271 APSIVTHYDSFLNAGYegqvGEPQLLVAT---PEESAKENQKALHNIFqAELGPSWkVNTSLSEKDTQISQEmnNTITTA 347
Cdd:TIGR03434 609 EPPRPEVYLPYAQSPD----RGMTLVVRTagdPAALAAAVRRAVRAID-PNLPVYD-VRTMEEQVDRSLAQE--RFLALL 680
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512048696  348 LGIIGGIVIALGALGLLTVSIVTIGHRVREIGIRRAMGASAGRIFISVFLESIVATTVAGVVGVIASIITVKqlPLDKML 427
Cdd:TIGR03434 681 LGLFAALALLLAAIGLYGVLAYSVAQRTREIGIRMALGAQRGDVLRLVLRQGLRLAAAGLAIGLAAALALAR--LLASLL 758
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 512048696  428 AlpletGAVAY-PVT-AAVIGVLVAtfVGALAGIIPATIAVRVKPIDAIR 475
Cdd:TIGR03434 759 F-----GVSPTdPLTfAAVAALLLA--VALLACYLPARRAARVDPMIALR 801
YbbP COG3127
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease ...
253-475 3.78e-13

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442361 [Multi-domain]  Cd Length: 830  Bit Score: 71.76  E-value: 3.78e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512048696 253 GNTTFTVVGVYKSL------GSWDAPSIVTHYDSFLNAGY--EGQVGEPQLLVATPEESAKENQKALhnifQAELGPSWK 324
Cdd:COG3127  159 GDATFTIAGVLTREpdrgggGFSLAPRVLINLADLEATGLiqPGSRVRYRYLVAGPDADLEALRAWL----EPALPAGQR 234
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512048696 325 VnTSLSEKDTQISQEMNNtITTALGIIGGIVIALGALG-LLTVSIVTIGHRvREIGIRRAMGASAGRIFISVFLESIVAT 403
Cdd:COG3127  235 V-RTVEDARPELGRALDR-AEQFLLLVALLALLLAGVAvANAARRYVARRL-DTIALLRCLGASRRQIFRIYLLQLLLLG 311
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 512048696 404 TVAGVVGVIASIITvkQLPLDKMLA--LPLETGAVAYPvTAAVIGVLVATFVGALAGIIPATIAVRVKPIDAIR 475
Cdd:COG3127  312 LLGSLLGLLLGALL--QALLAALLAdlLPVPLEPALSP-LPLLLGLLVGLLVLLLFALPPLLRLRRVPPLRVLR 382
FtsX pfam02687
FtsX-like permease family; This is a family of predicted permeases and hypothetical ...
349-470 7.68e-12

FtsX-like permease family; This is a family of predicted permeases and hypothetical transmembrane proteins. Swiss:P57382 has been shown to transport lipids targeted to the outer membrane across the inner membrane. Both Swiss:P57382 and Swiss:O54500 have been shown to require ATP. This region contains three transmembrane helices.


Pssm-ID: 460652 [Multi-domain]  Cd Length: 120  Bit Score: 62.27  E-value: 7.68e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512048696  349 GIIGGIVIALGALGLLTVSIVTIGHRVREIGIRRAMGASAGRIFISVFLESIVATTVAGVVGVIASIITVKqlPLDKMLA 428
Cdd:pfam02687   1 ILFSLLILLLAVLIILLLLSISISERRREIGILRALGASRKQIFKLLLLEALLIGLIGLVIGLLLGLLLAK--LIAILLY 78
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 512048696  429 LPLETGAVAYPVTAAVIGVLVATFVGALAGIIPATIAVRVKP 470
Cdd:pfam02687  79 SSGISLPILVPPLSILIALLLALLIALLASLLPALRIRKINP 120
PRK10535 PRK10535
macrolide ABC transporter ATP-binding protein/permease MacB;
253-474 1.17e-11

macrolide ABC transporter ATP-binding protein/permease MacB;


Pssm-ID: 182528 [Multi-domain]  Cd Length: 648  Bit Score: 67.06  E-value: 1.17e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512048696 253 GNTTFTVVGVY----------KSLGSWDAPSIVTHY---DSFLNA-------GYEGQVGEPQLLVATPEESAKENqkalh 312
Cdd:PRK10535 427 GNMPATVIGVAeekqsmfgssKVLRVWLPYSTMSGRvmgQSWLNSitvrvkeGYDSAEAEQQLTRLLTLRHGKKD----- 501
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512048696 313 nIFqaelgpSWKVNTSL--SEKDTQisqemnnTITTALGIIGGIVIALGALGLLTVSIVTIGHRVREIGIRRAMGASAGR 390
Cdd:PRK10535 502 -FF------TWNMDSVLktAEKTTR-------TLQLFLTLVAVISLVVGGIGVMNIMLVSVTERTREIGIRMAVGARASD 567
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512048696 391 IFISVFLESIVATTVAGVVGVIASIItvkqlpLDKMLALPLETGAVAYPVTAAVIGVLVATFVGALAGIIPATIAVRVKP 470
Cdd:PRK10535 568 VLQQFLIEAVLVCLVGGALGITLSLL------IAFTLQLFLPGWEIGFSPLALLSAFLCSTVTGILFGWLPARNAARLDP 641

                 ....
gi 512048696 471 IDAI 474
Cdd:PRK10535 642 VDAL 645
YbbP COG3127
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease ...
338-475 7.27e-11

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442361 [Multi-domain]  Cd Length: 830  Bit Score: 64.44  E-value: 7.27e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512048696 338 QEMNNTITTALGIIGGIVIALGALGLLTVSIVTIGHRVREIGIRRAMGASAGRIFISVFLESIVATTVAGVVGVIASIIT 417
Cdd:COG3127  697 RDILDQVSLAVEFLAGFALLAGLLVLAAALAASRDERTREAALLRTLGASRRQLRRALALEFALLGLLAGLLAALLAELA 776
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 512048696 418 ----VKQLpldkmLALPLetgavAYPVTAAVIGVLVATFVGALAGIIPATIAVRVKPIDAIR 475
Cdd:COG3127  777 gwalARFV-----FDLPF-----SPPWWLWLAGLLGGALLVLLAGLLGARRVLRQPPLEVLR 828
ADOP TIGR03434
Acidobacterial duplicated orphan permease; Members of this protein family are found, so far, ...
374-475 3.22e-07

Acidobacterial duplicated orphan permease; Members of this protein family are found, so far, only in three species of Acidobacteria, namely Acidobacteria bacterium Ellin345, Acidobacterium capsulatum ATCC 51196, and Solibacter usitatus Ellin6076, where they form large paralogous families. Each protein contains two copies of a domain called the efflux ABC transporter permease protein (pfam02687). However, unlike other members of that family (including LolC, FtsX, and MacB), genes for these proteins are essentially never found fused or adjacent to ABC transporter ATP-binding protein (pfam00005) genes. We name this family ADOP, for Acidobacterial Duplicated Orphan Permease, to reflect the restricted lineage, internal duplication, lack of associated ATP-binding cassette proteins, and permease homology. The function is unknown.


Pssm-ID: 274576 [Multi-domain]  Cd Length: 803  Bit Score: 52.90  E-value: 3.22e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512048696  374 RVREIGIRRAMGASAGRIFISVFLESIVATTVAGVVGVIASIITVKQLPLDKMLALPLETGAvayPVTAAVIG--VLVAT 451
Cdd:TIGR03434 300 RQREIAVRLALGAGRGRLVRQLLTESLLLALAGGALGLLLAYWGLRLLLALLPASLPRLLEI---SLDGRVLLfaLALSL 376
                          90       100
                  ....*....|....*....|....
gi 512048696  452 FVGALAGIIPATIAVRVKPIDAIR 475
Cdd:TIGR03434 377 LTGLLFGLAPALQATRSDLAEALK 400
FtsX COG2177
Cell division protein FtsX [Cell cycle control, cell division, chromosome partitioning];
342-467 4.55e-06

Cell division protein FtsX [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441780 [Multi-domain]  Cd Length: 292  Bit Score: 48.29  E-value: 4.55e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512048696 342 NTITTALGIIGGIVIALgaLGLLTVSIV------TIGHRVREIGIRRAMGASAGRIFISVFLESIVATTVAGVVGVIASI 415
Cdd:COG2177  160 FALLNLLRLVGLVLAAL--LLLAAVLLIgntirlAIYSRREEIEIMKLVGATDGFIRRPFLLEGALLGLLGGLLALLLLA 237
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 512048696 416 ITVKQLPLDKMLALPLETGAVAYPVTAAVIGVLVAtfVGALAGIIPATIAVR 467
Cdd:COG2177  238 LLYLLLVSALADGLAFLSLLSLGGLLLLLLLLLLL--LGALLGALGSRLAVR 287
COG4652 COG4652
Uncharacterized conserved protein, DUF1430 domain [Function unknown];
335-429 7.25e-03

Uncharacterized conserved protein, DUF1430 domain [Function unknown];


Pssm-ID: 443690 [Multi-domain]  Cd Length: 583  Bit Score: 38.92  E-value: 7.25e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512048696 335 QISQEMNNTITTALGI-IGGIVIALGALGLLTVSIVTI--GHRVREIGIRRAMGASAGRIFISVFLeSIVATTVAGVvgV 411
Cdd:COG4652  459 DEYAESLNETKRELRLlLIGAIISILILLLIIISLVLTyfELNRKRIFVRRLHGYSFLRRYKRYLL-LELGLWLLGL--A 535
                         90
                 ....*....|....*...
gi 512048696 412 IASIITVKQLPLDKMLAL 429
Cdd:COG4652  536 ISLIISHASLLYILLVAL 553
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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