|
Name |
Accession |
Description |
Interval |
E-value |
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
2-591 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 552.99 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 2 YVTTDIPQPD---KIAMADKTKVYYADGkTEIGSFAEQNREIINCSVLKPYVGNAIIASENRSFYKDGGIDLKGIGRAII 78
Cdd:COG0744 36 LYVADLPDPEeleDLALPQTSTIYDRDG-TLIATLGDENREWVPLDQIPPHLKDAVVAIEDRRFYEHGGVDPKGIARALV 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 79 HNVTS-KGRWGGSTITQQYAERYYLGETKTYLGKLHEAILALKIAQTQDKNTVLCNYMNTIYLGRGAYGIQAAAKAYFGV 157
Cdd:COG0744 115 ANLTAgGVVQGGSTITQQLVKNLFLSNERTLSRKLKEALLALKLERKYSKDEILELYLNTVYFGRGAYGIEAAAQYYFGK 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 158 EAKDLTLSQAAMLAGIIPAPSSWDPAIMPKEANMRFKRVLRIMLKDKYITSEEYKNAK-MPQTINQTKQNMYAGPQGYLL 236
Cdd:COG0744 195 SASDLTLAEAALLAGLVKAPSYYDPYRNPEAAKERRNLVLDRMVEQGYITQAEADAAKaEPLTLVPPPNGAAAGKYPYFV 274
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 237 QMVRSELTSggAFTKEDLDTGGYRIITTIDKAKQDLMFNVAspTAGARGITPQGVQTGAMSVNPKDGSIISVYAGDDYLS 316
Cdd:COG0744 275 DYVRRELEE--LLGEDDLYRGGLKIYTTLDPKLQKAAEKAV--KNVLPEGKPGGLQAALVVVDPKTGEVLAMVGGRDYGK 350
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 317 KPLNNATQALYEPGSTMKPFALIGAIQAGTNLNTLFNGNTgLKFKGIEKPVNNFANTNWGMINLYKATANSVNTPFMALQ 396
Cdd:COG0744 351 SQFNRATQAKRQPGSTFKPFVYAAALEQGYTPATTVDDEP-VTFPGGGWSPKNYDGRYRGPVTLREALANSLNTPAVRLA 429
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 397 EKLGQKGVANTAVMAGLNAQrvNGKNPFTVLGNDPVHISEIARAYSTIANQGRRPDLHIVSSVKNPDGKEFYRAPTVGKQ 476
Cdd:COG0744 430 QEVGLDKVVDTARRLGITSP--LDPNPSLALGTSEVSPLEMASAYATFANGGVYVEPHAITKVTDADGKVLYEAKPKCEQ 507
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 477 VFAAADMALAIKAMQGVVQYGTSPEVRGVGKPIAGKSGTANDASACSFVGFTPSVLTVFAIWNPDaqGNPLPVPTfrgyp 556
Cdd:COG0744 508 VISPEVAYLMTDMLQDVVTSGTGRAARLPGRPVAGKTGTTNDNRDAWFVGYTPQLVTAVWVGNDD--NSPMGYVT----- 580
|
570 580 590
....*....|....*....|....*....|....*
gi 514588806 557 gGIGYSAHLFTRYMRAALAGTAAEKFPEAKDNGKI 591
Cdd:COG0744 581 -GGSLPAPIWRDFMEAALEGLPVEDFPKPSGVVRI 614
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
37-576 |
6.88e-115 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 354.64 E-value: 6.88e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 37 NREIINCSVLKPYVGNAIIASENRSFYKDGGIDLKGIGRAIIHNVTSKGRW-GGSTITQQYAERYYLGETKTYLGKLHEA 115
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVANITSGRVLeGGSTITQQLAKNLYLTNERTITRKIQEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 116 ILALKIAQTQDKNTVLCNYMNTIYLGRGAYGIQAAAKAYFGVEAKDLTLSQAAMLAGIIPAPSSWDPAIMPKEANMRFKR 195
Cdd:TIGR02074 81 LLALKLEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKDRRNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 196 VLRIMLKDKYITSEEYKNAK--MPQTINQTKQ-NMYAGPqgYLLQMVRSELTSggaFTKEDLDTGGYRIITTIDKAKQDL 272
Cdd:TIGR02074 161 VLSNMVENGYITAEEAEEAInePIQLYLQTKKsEQYKAP--YFVDYVIQELEE---EYGEELYTGGLKIYTTLDLDAQKA 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 273 MFN-VASPTAGARGITPQGVQTGAMSVNPKDGSIISVYAGDDYLSKPLNNATQALYEPGSTMKPFALIGAIQAGTNLNTL 351
Cdd:TIGR02074 236 AEKvLNTGLRVAGRRDGDDLQAALVAIDPDTGAVRALVGGRDYGKSQFNRATQAKRQPGSTFKPFVYAAALEKGLTPATI 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 352 -------FNGNTGLKFKgiekpvnNFANTNWGMINLYKATANSVNTPFMALQEKLGQKGVANTAVMAGLNAQRVngKNPF 424
Cdd:TIGR02074 316 vndepitYNGNGPWSPK-------NYGGGYRGNVTLRQALAQSRNIPAVRLLQEVGLDKVVALAKRFGITSPLD--PVLS 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 425 TVLGNDPVHISEIARAYSTIANQGRRPDLHIVSSVKNPDGKEFYRAPTVGKQVFAAADMALAIKAMQGVVQYGTSPEVRG 504
Cdd:TIGR02074 387 LALGTVEVSPLEMASAYAVFANGGKYVEPHGIRKIVDRDGKVIYENKPKTTQVISPATAYIMTDMLKGVVESGTGRSARL 466
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 514588806 505 VGKPIAGKSGTANDASACSFVGFTPSVLTvfAIWNPDAQGNPLPVPTfrgypGGIGYSAHLFTRYMRAALAG 576
Cdd:TIGR02074 467 PGRPVAGKTGTTQNWRDAWFVGYTPYYVT--AVWVGYDDKKTLGKSG-----TGGGLAAPIWRDFMAEALKN 531
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
28-201 |
1.75e-71 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 228.95 E-value: 1.75e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 28 TEIGSFAEQNREIINCSVLKPYVGNAIIASENRSFYKDGGIDLKGIGRAIIHNVTSKGRW-GGSTITQQYAERYYLGETK 106
Cdd:pfam00912 3 TLLAELGEENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRIVqGGSTITQQLAKNLFLTPER 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 107 TYLGKLHEAILALKIAQTQDKNTVLCNYMNTIYLGRGAYGIQAAAKAYFGVEAKDLTLSQAAMLAGIIPAPSSWDPAIMP 186
Cdd:pfam00912 83 TLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNPLRNP 162
|
170
....*....|....*
gi 514588806 187 KEANMRFKRVLRIML 201
Cdd:pfam00912 163 ERAKRRRNLVLDRMV 177
|
|
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
20-470 |
1.71e-47 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 179.94 E-value: 1.71e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 20 KVYYADGKTeIGSFAEQNREIINCSVLKPYVGNAIIASENRSFYKDGGIDLKGIGRAIIHNVTS-KGRWGGSTITQQYAE 98
Cdd:PRK11636 49 QVYSADGEL-IAQYGEKRRIPLTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAASVALFSgHASQGASTITQQLAR 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 99 RYYLGETKTYLGKLHEAILALKIAQTQDKNTVLCNYMNTIYLGRGAYGIQAAAKAYFGVEAKDLTLSQAAMLAGIIPAPS 178
Cdd:PRK11636 128 NFFLSPERTLMRKIKEAFLAIRIEQLLTKDEILELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLSEMAVIAGLPKAPS 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 179 SWDPAIMPKEANMRFKRVLRIMLKDKYITSEEYKNAKMPQTINQtkqnmYAGPQ-----GYLLQMVRSELTSGGAftkED 253
Cdd:PRK11636 208 TFNPLYSMDRAVARRNVVLSRMLDEGYITQAQYDQARSEPIVAN-----YHAPEiafsaPYLSEMVRQEMYNRYG---EN 279
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 254 LDTGGYRIITTIDK----AKQDLMFN------------------------------------------------------ 275
Cdd:PRK11636 280 AYEDGYRVYTTITRkvqqAAQQAVRNnvldydmrhgyrgpanvlwkvgesawdnkkitdtlkalptygpllpavvtsanp 359
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 276 ------------VASPTAGAR-----------GITPQGV----QTGA-----------------------MSVNPKDGSI 305
Cdd:PRK11636 360 qeatamladgssVALPMEGVRwarpyrsdtqqGPTPRKVtdvvQTGQqiwvrqvddawwlaqvpdvnsalVSINPQNGAV 439
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 306 ISVYAGDDYLSKPLNNATQALYEPGSTMKPFALIGAIQAGTNLNTLFNgntglkfkgiEKPVNNF---ANTNW------- 375
Cdd:PRK11636 440 MALVGGFDFNQSKFNRATQALRQVGSNIKPFLYTAAMDKGLTLASMLN----------DVPISRWdagAGSDWrpknspp 509
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 376 ---GMINLYKATANSVNTPFMALQEKLGQKGVANTAVMAGLNAQRVN-------GKNPFTVLgndpvhisEIARAYSTIA 445
Cdd:PRK11636 510 qyaGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPAQNIVhteslalGSASFTPM--------QVARGYAVMA 581
|
570 580
....*....|....*....|....*
gi 514588806 446 NQGRRPDLHIVSSVKNPDGKEFYRA 470
Cdd:PRK11636 582 NGGFLVDPYFISKIENDQGGVIFEA 606
|
|
| strep_PBP2X |
NF038271 |
penicillin-binding protein PBP2X; |
289-520 |
4.32e-06 |
|
penicillin-binding protein PBP2X;
Pssm-ID: 468442 [Multi-domain] Cd Length: 748 Bit Score: 50.01 E-value: 4.32e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 289 QGVQTGAMSVNPKDGSIISV-----YAGD--DYLSKPLNNATQALY----EPGSTMKPFALIGAIQAGT-NLNTLFNGNT 356
Cdd:NF038271 282 KGKYASATLVNAKTGEILATtqrptYNADtkEGLDKKDLNWNNLLYqtnyEPGSTMKVMTLASAIDNGTfNPNETYSNSN 361
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 357 GLKFKGIEkpVNNFaNTNWGM-----INLYKATANSVNTPFMALQEKLGQK-----------GVANTAVMAGLNAQRVNG 420
Cdd:NF038271 362 GLTIADAT--INDW-DVNEGLstgqyMTYAQGFAYSSNVGMTLLEQKMGDDkwlnylskfkfGLPTRFGMGDESSGILPS 438
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 421 KNPFTV----LGND-PVHISEIARAYSTIANQGRRPDLHIVSSVKNPDGKEFYRAPT--VGKQVFAAAdmalAIKAMQGV 493
Cdd:NF038271 439 DNIVTIamssFGQGiSVTQVQMLRAFSAISNDGVMLEPKFISAIYDPNTGTARKSKKevVGKPVSKDA----ASQTRNYM 514
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 514588806 494 VQYGTSPEV-----RGVGKPI--------AGKSGTANDAS 520
Cdd:NF038271 515 VTVGTDPYYgtlysKTTGGPIiqvgnysvAVKSGTAQIAK 554
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
2-591 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 552.99 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 2 YVTTDIPQPD---KIAMADKTKVYYADGkTEIGSFAEQNREIINCSVLKPYVGNAIIASENRSFYKDGGIDLKGIGRAII 78
Cdd:COG0744 36 LYVADLPDPEeleDLALPQTSTIYDRDG-TLIATLGDENREWVPLDQIPPHLKDAVVAIEDRRFYEHGGVDPKGIARALV 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 79 HNVTS-KGRWGGSTITQQYAERYYLGETKTYLGKLHEAILALKIAQTQDKNTVLCNYMNTIYLGRGAYGIQAAAKAYFGV 157
Cdd:COG0744 115 ANLTAgGVVQGGSTITQQLVKNLFLSNERTLSRKLKEALLALKLERKYSKDEILELYLNTVYFGRGAYGIEAAAQYYFGK 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 158 EAKDLTLSQAAMLAGIIPAPSSWDPAIMPKEANMRFKRVLRIMLKDKYITSEEYKNAK-MPQTINQTKQNMYAGPQGYLL 236
Cdd:COG0744 195 SASDLTLAEAALLAGLVKAPSYYDPYRNPEAAKERRNLVLDRMVEQGYITQAEADAAKaEPLTLVPPPNGAAAGKYPYFV 274
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 237 QMVRSELTSggAFTKEDLDTGGYRIITTIDKAKQDLMFNVAspTAGARGITPQGVQTGAMSVNPKDGSIISVYAGDDYLS 316
Cdd:COG0744 275 DYVRRELEE--LLGEDDLYRGGLKIYTTLDPKLQKAAEKAV--KNVLPEGKPGGLQAALVVVDPKTGEVLAMVGGRDYGK 350
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 317 KPLNNATQALYEPGSTMKPFALIGAIQAGTNLNTLFNGNTgLKFKGIEKPVNNFANTNWGMINLYKATANSVNTPFMALQ 396
Cdd:COG0744 351 SQFNRATQAKRQPGSTFKPFVYAAALEQGYTPATTVDDEP-VTFPGGGWSPKNYDGRYRGPVTLREALANSLNTPAVRLA 429
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 397 EKLGQKGVANTAVMAGLNAQrvNGKNPFTVLGNDPVHISEIARAYSTIANQGRRPDLHIVSSVKNPDGKEFYRAPTVGKQ 476
Cdd:COG0744 430 QEVGLDKVVDTARRLGITSP--LDPNPSLALGTSEVSPLEMASAYATFANGGVYVEPHAITKVTDADGKVLYEAKPKCEQ 507
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 477 VFAAADMALAIKAMQGVVQYGTSPEVRGVGKPIAGKSGTANDASACSFVGFTPSVLTVFAIWNPDaqGNPLPVPTfrgyp 556
Cdd:COG0744 508 VISPEVAYLMTDMLQDVVTSGTGRAARLPGRPVAGKTGTTNDNRDAWFVGYTPQLVTAVWVGNDD--NSPMGYVT----- 580
|
570 580 590
....*....|....*....|....*....|....*
gi 514588806 557 gGIGYSAHLFTRYMRAALAGTAAEKFPEAKDNGKI 591
Cdd:COG0744 581 -GGSLPAPIWRDFMEAALEGLPVEDFPKPSGVVRI 614
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
37-576 |
6.88e-115 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 354.64 E-value: 6.88e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 37 NREIINCSVLKPYVGNAIIASENRSFYKDGGIDLKGIGRAIIHNVTSKGRW-GGSTITQQYAERYYLGETKTYLGKLHEA 115
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVANITSGRVLeGGSTITQQLAKNLYLTNERTITRKIQEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 116 ILALKIAQTQDKNTVLCNYMNTIYLGRGAYGIQAAAKAYFGVEAKDLTLSQAAMLAGIIPAPSSWDPAIMPKEANMRFKR 195
Cdd:TIGR02074 81 LLALKLEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKDRRNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 196 VLRIMLKDKYITSEEYKNAK--MPQTINQTKQ-NMYAGPqgYLLQMVRSELTSggaFTKEDLDTGGYRIITTIDKAKQDL 272
Cdd:TIGR02074 161 VLSNMVENGYITAEEAEEAInePIQLYLQTKKsEQYKAP--YFVDYVIQELEE---EYGEELYTGGLKIYTTLDLDAQKA 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 273 MFN-VASPTAGARGITPQGVQTGAMSVNPKDGSIISVYAGDDYLSKPLNNATQALYEPGSTMKPFALIGAIQAGTNLNTL 351
Cdd:TIGR02074 236 AEKvLNTGLRVAGRRDGDDLQAALVAIDPDTGAVRALVGGRDYGKSQFNRATQAKRQPGSTFKPFVYAAALEKGLTPATI 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 352 -------FNGNTGLKFKgiekpvnNFANTNWGMINLYKATANSVNTPFMALQEKLGQKGVANTAVMAGLNAQRVngKNPF 424
Cdd:TIGR02074 316 vndepitYNGNGPWSPK-------NYGGGYRGNVTLRQALAQSRNIPAVRLLQEVGLDKVVALAKRFGITSPLD--PVLS 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 425 TVLGNDPVHISEIARAYSTIANQGRRPDLHIVSSVKNPDGKEFYRAPTVGKQVFAAADMALAIKAMQGVVQYGTSPEVRG 504
Cdd:TIGR02074 387 LALGTVEVSPLEMASAYAVFANGGKYVEPHGIRKIVDRDGKVIYENKPKTTQVISPATAYIMTDMLKGVVESGTGRSARL 466
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 514588806 505 VGKPIAGKSGTANDASACSFVGFTPSVLTvfAIWNPDAQGNPLPVPTfrgypGGIGYSAHLFTRYMRAALAG 576
Cdd:TIGR02074 467 PGRPVAGKTGTTQNWRDAWFVGYTPYYVT--AVWVGYDDKKTLGKSG-----TGGGLAAPIWRDFMAEALKN 531
|
|
| MrcA |
COG5009 |
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis]; |
19-583 |
8.97e-104 |
|
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 444033 [Multi-domain] Cd Length: 785 Bit Score: 333.28 E-value: 8.97e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 19 TKVYYADGKtEIGSFAEQNREIINCSVLKPYVGNAIIASENRSFYKDGGIDLKGIGRAIIHNVTSKGRW-GGSTITQQYA 97
Cdd:COG5009 48 SRVYSADGK-LIAEFGEERRIPVPIEEIPPLLINAFLAAEDKRFYEHPGVDPIGIARAAVVNLRTGRRVqGGSTITQQVA 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 98 ERYYLGETKTYLGKLHEAILALKIAQTQDKNTVLCNYMNTIYLGRGAYGIQAAAKAYFGVEAKDLTLSQAAMLAGIIPAP 177
Cdd:COG5009 127 KNFLLSPERTLTRKIKEAILALRIEQELSKDEILELYLNKIYLGHRAYGVAAAAQTYFGKSLDELTLAEAAMLAGLPKAP 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 178 SSWDPAIMPKEANMRFKRVLRIMLKDKYITSEEYKNAK-MPQTINQTKQNmYAGPQGYLLQMVRSELTSggAFTKEDLDT 256
Cdd:COG5009 207 SRYNPIRNPERALERRNYVLGRMLELGYITQAEYEAAKaEPLTARYHGAS-AEVDAPYFAEMVRRELVE--RYGEDALYT 283
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 257 GGYRIITTIDKAKQD-------------------------------------------------LMFNVASPTA------ 281
Cdd:COG5009 284 GGLKVYTTLDPRLQEaaekalrdgllaydrrhgyrgpeahldlaeedwdealaevpdvgdlrpaVVLEVDDKSArvglrd 363
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 282 --------------------GARGITPQG----------------------------VQTGAMSVNPKDGSIISVYAGDD 313
Cdd:COG5009 364 getgtlpleglkwarpyindNRRGPAPKSasdvlkpgdvirvrpvadggwrlrqipeVQGALVALDPHTGAVLALVGGFD 443
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 314 Y-LSKpLNNATQALYEPGSTMKPFALIGAIQAGTNLNTLFN--------GNTGlkfkGIEKPvNNFANTNWGMINLYKAT 384
Cdd:COG5009 444 FeQSK-FNRATQAKRQPGSSFKPFVYAAALDNGYTPATIINdapivfddGGGG----GVWRP-KNYSGKFYGPTTLREAL 517
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 385 ANSVNTPFMALQEKLGQKGVANTAVMAGLNAQrvNGKNPFTVLGNDPVHISEIARAYSTIANQGRRPDLHIVSSVKNPDG 464
Cdd:COG5009 518 EKSRNLVTVRLLQDVGIDYVIDYAERFGIYSK--LPPNLSLALGSGEVTPLEMARAYAVFANGGYRVEPYLIDRIEDRNG 595
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 465 KEFYRA---------------------PTVGKQVFAAADMALAIKAMQGVVQYGTSPEVRGVGKPIAGKSGTANDASACS 523
Cdd:COG5009 596 KVIYRAdparacedcdaaewdgaeprlPDPAEQVIDPRTAYQMTSMLRGVVQRGTGRRARALGRDIAGKTGTTNDSKDAW 675
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 514588806 524 FVGFTPSVLTVfaIW----NPdaqgNPLpvptfrgypGGIGYSAHL----FTRYMRAALAGTAAEKFP 583
Cdd:COG5009 676 FVGFTPDLVAG--VWvgfdDP----RSL---------GRGETGGRAalpiWIDFMKAALKDKPEKPFP 728
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
28-201 |
1.75e-71 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 228.95 E-value: 1.75e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 28 TEIGSFAEQNREIINCSVLKPYVGNAIIASENRSFYKDGGIDLKGIGRAIIHNVTSKGRW-GGSTITQQYAERYYLGETK 106
Cdd:pfam00912 3 TLLAELGEENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRIVqGGSTITQQLAKNLFLTPER 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 107 TYLGKLHEAILALKIAQTQDKNTVLCNYMNTIYLGRGAYGIQAAAKAYFGVEAKDLTLSQAAMLAGIIPAPSSWDPAIMP 186
Cdd:pfam00912 83 TLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNPLRNP 162
|
170
....*....|....*
gi 514588806 187 KEANMRFKRVLRIML 201
Cdd:pfam00912 163 ERAKRRRNLVLDRMV 177
|
|
| PbpC |
COG4953 |
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope ... |
53-546 |
1.08e-49 |
|
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443980 [Multi-domain] Cd Length: 773 Bit Score: 185.42 E-value: 1.08e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 53 AIIASENRSFYKDGGIDLKGIGRAIIHNVTSKGRW-GGSTITQQYAeRYYLGETKTYLGKLHEAILALKIAQTQDKNTVL 131
Cdd:COG4953 80 ALLAYEDRRFYYHPGVNPLALLRAAWQNLRSGRIVsGGSTLTMQVA-RLLEPRPRTLSGKLRQILRALQLERRYSKDEIL 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 132 CNYMNTIYLGRGAYGIQAAAKAYFGVEAKDLTLSQAAMLAgIIP-APSSWDPAIMPKEANMRFKRVLRIMLKDKYITSEE 210
Cdd:COG4953 159 ELYLNLAPYGGNIEGVEAASLAYFGKPPSRLSLAEAALLA-VLPqAPSRRRPDRNPERARAARDRVLARLAEAGVIDAEE 237
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 211 YKNAKMPqTINQTKQNMyagPQG--YLLQMVRSELTSGGaftkedldtggyRIITTIDKAKQDLMFNVASptAGARGITP 288
Cdd:COG4953 238 AALALLE-PVPARRRPL---PQLapHLARRLLRQLPGGT------------RIRTTLDAGLQRRLERLVR--RYVRRLKQ 299
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 289 QGVQTGAMSV-NPKDGSIISvYAGD-DYLSKPL---NNATQALYEPGSTMKPF--ALigAIQAGtnlntLFNGNTGLK-- 359
Cdd:COG4953 300 NGIHNAAVLVvDNRTGEVLA-YVGSaDFFDASRqgqVDMVRALRSPGSTLKPFlyGL--ALDQG-----LIHPETLLAdv 371
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 360 ---FKGIEkPVnNFANTNWGMINLYKATANSVNTPFMALQEKLGQKGVANTAVMAGLNAQRVNGKNP--FTVLGNDPVHI 434
Cdd:COG4953 372 ptsFGGYR-PE-NFDGTFQGPVSAREALARSLNIPAVRLLEALGPARFYARLRRAGLRLLLPPAEHYglSLILGGAEVTL 449
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 435 SEIARAYSTIANQGRRPDLHIVSSVKnpdgkefyraPTVGKQVFAAADMALAIKAMQGVVQ--YGTSPEVRGVGKPIAGK 512
Cdd:COG4953 450 EELVGLYAALARGGEARPLRLLAGEP----------ASPGRRLLSPGAAWLVRDILSDVPRpdGAFGWRALDSPPPIAWK 519
|
490 500 510
....*....|....*....|....*....|....*....
gi 514588806 513 SGTAN---DASAcsfVGFTPSVltVFAIW--NPDAQGNP 546
Cdd:COG4953 520 TGTSYgfrDAWA---VGFTGRY--TVGVWvgNPDGTPVP 553
|
|
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
20-470 |
1.71e-47 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 179.94 E-value: 1.71e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 20 KVYYADGKTeIGSFAEQNREIINCSVLKPYVGNAIIASENRSFYKDGGIDLKGIGRAIIHNVTS-KGRWGGSTITQQYAE 98
Cdd:PRK11636 49 QVYSADGEL-IAQYGEKRRIPLTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAASVALFSgHASQGASTITQQLAR 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 99 RYYLGETKTYLGKLHEAILALKIAQTQDKNTVLCNYMNTIYLGRGAYGIQAAAKAYFGVEAKDLTLSQAAMLAGIIPAPS 178
Cdd:PRK11636 128 NFFLSPERTLMRKIKEAFLAIRIEQLLTKDEILELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLSEMAVIAGLPKAPS 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 179 SWDPAIMPKEANMRFKRVLRIMLKDKYITSEEYKNAKMPQTINQtkqnmYAGPQ-----GYLLQMVRSELTSGGAftkED 253
Cdd:PRK11636 208 TFNPLYSMDRAVARRNVVLSRMLDEGYITQAQYDQARSEPIVAN-----YHAPEiafsaPYLSEMVRQEMYNRYG---EN 279
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 254 LDTGGYRIITTIDK----AKQDLMFN------------------------------------------------------ 275
Cdd:PRK11636 280 AYEDGYRVYTTITRkvqqAAQQAVRNnvldydmrhgyrgpanvlwkvgesawdnkkitdtlkalptygpllpavvtsanp 359
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 276 ------------VASPTAGAR-----------GITPQGV----QTGA-----------------------MSVNPKDGSI 305
Cdd:PRK11636 360 qeatamladgssVALPMEGVRwarpyrsdtqqGPTPRKVtdvvQTGQqiwvrqvddawwlaqvpdvnsalVSINPQNGAV 439
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 306 ISVYAGDDYLSKPLNNATQALYEPGSTMKPFALIGAIQAGTNLNTLFNgntglkfkgiEKPVNNF---ANTNW------- 375
Cdd:PRK11636 440 MALVGGFDFNQSKFNRATQALRQVGSNIKPFLYTAAMDKGLTLASMLN----------DVPISRWdagAGSDWrpknspp 509
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 376 ---GMINLYKATANSVNTPFMALQEKLGQKGVANTAVMAGLNAQRVN-------GKNPFTVLgndpvhisEIARAYSTIA 445
Cdd:PRK11636 510 qyaGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPAQNIVhteslalGSASFTPM--------QVARGYAVMA 581
|
570 580
....*....|....*....|....*
gi 514588806 446 NQGRRPDLHIVSSVKNPDGKEFYRA 470
Cdd:PRK11636 582 NGGFLVDPYFISKIENDQGGVIFEA 606
|
|
| mrcB |
PRK09506 |
bifunctional glycosyl transferase/transpeptidase; Reviewed |
52-526 |
1.33e-45 |
|
bifunctional glycosyl transferase/transpeptidase; Reviewed
Pssm-ID: 236544 [Multi-domain] Cd Length: 830 Bit Score: 174.19 E-value: 1.33e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 52 NAIIASENRSFYKDGGIDLKGIGRAIIHNVTSkGR--WGGSTITQQYAERYYLGETKTYLGKLHEAILALKIAQTQDKNT 129
Cdd:PRK09506 225 DTLLATEDRHFYEHDGISLYSIGRAVLANLTA-GRtvQGGSTLTQQLVKNLFLSNERSLWRKANEAYMALIMDARYSKDR 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 130 VLCNYMNTIYLGRGA----YGIQAAAKAYFGVEAKDLTLSQAAMLAGIIPAPSSWDPAIMPKEANMRFKRVLRIMLKDKY 205
Cdd:PRK09506 304 ILELYLNEVYLGQSGddqiRGFPLASLYYFGRPVEELSLDQQALLVGMVKGASLYNPWRNPKLALERRNLVLRLLQQQQI 383
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 206 ITSEEYKNAKMPQTINQTKQNMYAgPQGYLLQMVRSELTSGGAFTKEDLDtgGYRIITTIDKAKQDlmfnvASPTAGARG 285
Cdd:PRK09506 384 IDQELYDMLSARPLGVQPKGGVIS-PQPAFMQMVRQELQAKLGDKVKDLS--GVKIFTTLDPVSQD-----AAEKAVEEG 455
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 286 I----TPQGVQ--TGAMSVNPK-DGSIISVYAGDDYLSKPLNNATQALYEPGSTMKPFALIGAI-QAGT-NLNT-LFNGN 355
Cdd:PRK09506 456 IpalkKQRKLSdlETAMVVVDRfSGEVRAMVGGSEPQFAGYNRAMQARRSIGSLAKPATYLTALsQPDKyRLNTwIADAP 535
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 356 TGLKFKG--IEKPvNNFANTNWGMINLYKATANSVNTPFMALQEKLGQKGVANTAVMAGLNAQRVNgKNPFTVLGNDPVH 433
Cdd:PRK09506 536 ISLRQPNgqVWSP-QNDDRRFSGRVMLVDALTRSMNVPTVNLGMALGLPAVTDTWIKLGVPKDQLN-PVPAMLLGALNLT 613
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 434 ISEIARAYSTIANQGRRPDLHIVSSVKNPDGKEFYRAPTVGKQVFAAADMALAIKAMQGVVQYGTSPE--VRGVGKPIAG 511
Cdd:PRK09506 614 PIEVAQAFQTIASGGNRAPLSALRSVIAEDGKVLYQSFPQAERAVPAQAAYLTLYTMQQVVQRGTGRQlgAKYPNLHLAG 693
|
490
....*....|....*
gi 514588806 512 KSGTANDASACSFVG 526
Cdd:PRK09506 694 KTGTTNDLVDSWFAG 708
|
|
| PBP_1c |
TIGR02073 |
penicillin-binding protein 1C; This subfamily of the penicillin binding proteins includes the ... |
53-546 |
2.28e-44 |
|
penicillin-binding protein 1C; This subfamily of the penicillin binding proteins includes the member from E. coli designated penicillin-binding protein 1C. Members have both transglycosylase and transpeptidase domains and are involved in forming cross-links in the late stages of peptidoglycan biosynthesis. All members of this subfamily are presumed to have the same basic function. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273954 [Multi-domain] Cd Length: 727 Bit Score: 169.52 E-value: 2.28e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 53 AIIASENRSFYKDGGIDLKGIGRAIIHNVTSKGR-WGGSTITQQYAERYYLGETKTYLGKLHEAILALKIAQTQDKNTVL 131
Cdd:TIGR02073 48 ALLLYEDKRFYWHPGVNPLALLRAAWQNLTNGRRvSGGSTLTMQLARLLDPELSRTLTGKLRQMWRAIQLEARYSKREIL 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 132 CNYMNTIYLGRGAYGIQAAAKAYFGVEAKDLTLSQAAMLAGIIPAPSSWDPAIMPKEANMRFKRVLRIMLKDKYITSEEY 211
Cdd:TIGR02073 128 EAYLNLAPYGGNLEGLRAASLIYFGKEPSSLSLAEAALLAALPQAPSARRLDRLPKAAKAARDRLLDRMVEQGPDDSEQV 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 212 KNAKMPQTINQTKQNMYAGPqgYLLQMVRSEltsggafTKEDLDTggyrIITTIDKAKQDLMFNVASPTAGARGitPQGV 291
Cdd:TIGR02073 208 ALAALEPLPALPEPLPQLAP--HFALKLLRA-------RPEIASV----IVSTLDADLQRRLEELARRYLSALR--PRGI 272
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 292 QTGAMSV-NPKDGSIISvYAGDDYLSKPLN----NATQALYEPGSTMKPFALIGAIQAGtnlntLFNGNTGLKfkgiEKP 366
Cdd:TIGR02073 273 SNLAILVvDNRSGAVLA-YVGSADFFDDSNsgqvDGVRAPRSPGSTLKPFLYALALDDG-----LLHPDSLLK----DVP 342
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 367 VN-------NFANTNWGMINLYKATANSVNTPFMALQEKLGQKGVANTAVMAGLNAQRVNGKNPFT--VLGNDPVHISEI 437
Cdd:TIGR02073 343 LRfgdyapeNFDKTFHGPVPAREALARSLNIPAVRLLERVGPPRFADFLRQAGLNLLKPKSDYYGLslALGGAEITLQDL 422
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 438 ARAYSTIANQGRRPDLHIVSSV-KNPDGKEFYRAptvgkqvfAAADMALAIKAMQGVVQYGTSPEVRGVGKPIAGKSGTA 516
Cdd:TIGR02073 423 ANLYAMLANQGLSGPLRFLQTDaKRPERERLLSP--------GAAWIVLDILKDRPRPDDTLPLSALPTRLPLAWKTGTS 494
|
490 500 510
....*....|....*....|....*....|....*
gi 514588806 517 N---DASAcsfVGFTPSVltVFAIW--NPDAQGNP 546
Cdd:TIGR02073 495 YgfrDAWA---AGVSGRY--TIGVWvgNFDGKPNP 524
|
|
| PRK14850 |
PRK14850 |
penicillin-binding protein 1b; Provisional |
54-526 |
1.22e-40 |
|
penicillin-binding protein 1b; Provisional
Pssm-ID: 237835 [Multi-domain] Cd Length: 764 Bit Score: 158.86 E-value: 1.22e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 54 IIASENRSFYKDGGIDLKGIGRAIIHNVTSkGR--WGGSTITQQYAERYYLGETKTYLGKLHEAILALKIAQTQDKNTVL 131
Cdd:PRK14850 173 LLAIEDKYFYEHDGIHLSSIGRAFLVNLMS-GHtiQGGSTLTQQLVKNLFLTNTRSLWRKINEIYMALILDRFYSKDRIL 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 132 CNYMNTIYLGRGA----YGIQAAAKAYFGVEAKDLTLSQAAMLAGIIPAPSSWDPAIMPKEANMRFKRVLRIMLKDKYIT 207
Cdd:PRK14850 252 ELYLNEVYLGQDGneqiRGFPLASIYYFGRPINELNLDQYALLVGMVKGASLYNPWTNPNLTLKRRNLVLFLLYKQKVIT 331
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 208 SEEYKNAKMPQTINQTKQNMYAGPQGYlLQMVRSELTSGGAFTKEDLDtgGYRIITTIDKAKQdlmfnVASPTAGARGI- 286
Cdd:PRK14850 332 RKLYKDLCSRPLNVQSKGNIISSHPAF-IQLVCEEFHKKIHYPFKNFS--GTKIFTTLDYISQ-----NAAEQAVKIGIp 403
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 287 ------TPQGVQTGAMSVNPKDGSIISVYAGDDYLSKPLNNATQALYEPGSTMKPFALIGAIQAGT--NLNTLFnGNTGL 358
Cdd:PRK14850 404 ilkrkkRLKDLEVAMVIIDRFSGEVRALIGSSKPEFNGYNRALKARRSIGSLSKPITYLTALSQPEkyHLNTWI-SDTPI 482
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 359 KFK----GIEKPVNNfaNTNW-GMINLYKATANSVNTPFMALQEKLGQKGVANTAVMAGLNAQRVNgKNPFTVLGNDPVH 433
Cdd:PRK14850 483 SIKldngQYWTPKNN--NFSFsGKVMLIDALIHSINIPTVHLSINLGLKKLVDSWILLGISSNYIT-PLPSISLGAINLT 559
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 434 ISEIARAYSTIANQGRRPDLHIVSSVKNPDGKEFYRAPTVGKQVFAAADMALAIKAMQGVVQYGTSPEVRGVGK--PIAG 511
Cdd:PRK14850 560 PMEVAQVFQIIGSGGYKSSLSSIRSIISDDNKVLYQNFPQSKHVESSQASYLTLYAMQQVVKSGTAKSLGTIFKefSLAG 639
|
490
....*....|....*
gi 514588806 512 KSGTANDASACSFVG 526
Cdd:PRK14850 640 KTGTTNNLVDSWFVG 654
|
|
| FtsI |
COG0768 |
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ... |
258-529 |
5.35e-35 |
|
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain] Cd Length: 568 Bit Score: 139.96 E-value: 5.35e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 258 GYRIITTIDKAKQDLMFNVAsptagARGITPQGVQTGAMSV-NPKDGSII----------SVYAgdDYLSKPLNN-ATQA 325
Cdd:COG0768 218 GKDLVLTIDSDLQKIAEEAL-----KKAVEEYKAKSGAVVVmDPKTGEILamasypsfdpNLFV--GGPDEPLRNrAVQG 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 326 LYEPGSTMKPFALIGAIQAGT-NLNTLFNGNTGLKFKGieKPVNNFANTNWGMINLYKATANSVNTPFMALQEKLGQKGV 404
Cdd:COG0768 291 TYEPGSTFKPFTAAAALEEGViTPDTTFDCPGYYRVGG--RTIRDWDRGGHGTLTLTEALAKSSNVGFYKLALRLGIDKL 368
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 405 ANTAVMAGLNAQ-----------RVNGKNPFTVLgnDPVHIS----------EIARAYSTIANQGRRPDLHIVSSVKNPD 463
Cdd:COG0768 369 YDYLKKFGLGQKtgidlpgeasgLLPSPKRWYPG--ETATMSigqglsvtplQLAQAYAAIANGGVLVKPHLVKEIVDPD 446
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 514588806 464 GKEFYRAPTVGKQVFAAADMALAIKAMQGVVQ--YGTSPEVRGVGKPIAGKSGTA-----------NDASACSFVGFTP 529
Cdd:COG0768 447 GEVVKEEPEVLRRVISPETAETVREGMEGVVNepGGTARRAAIPGYRVAGKTGTAqvvdignggyyKGRHIASFVGFAP 525
|
|
| PRK13481 |
PRK13481 |
glycosyltransferase; Provisional |
35-214 |
1.11e-31 |
|
glycosyltransferase; Provisional
Pssm-ID: 184078 [Multi-domain] Cd Length: 232 Bit Score: 122.99 E-value: 1.11e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 35 EQNREIINCSVLKPYVGNAIIASENRSFYKDGGIDLKGIGRAIIHNVTSKGRWGGSTITQQYAERYYLGETKTYLGKLHE 114
Cdd:PRK13481 42 ENKSSFVSADNMPEYVKGAFISMEDERFYKHHGFDLKGTTRALFSTISDRDVQGGSTITQQVVKNYFYDNERSFTRKVKE 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 115 AILALKIAQTQDKNTVLCNYMNTIYLGRGAYGIQAAAKAYFGVEAK-------DLTLSQAAMLAGIIPAPSSWDPAIMPK 187
Cdd:PRK13481 122 LFVAHRVEKQYSKNEILSFYLNNIYFGDNQYTLEGAANHYFGTTVNknsttmsHITVLQSAILASKVNAPSVYNINDMSE 201
|
170 180
....*....|....*....|....*..
gi 514588806 188 EANMRFKRVLRIMLKDKYITSEEYKNA 214
Cdd:PRK13481 202 NFTQRVSTNLEKMKQQNYINETQYQQA 228
|
|
| mono_pep_trsgly |
TIGR02070 |
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the ... |
53-181 |
1.43e-28 |
|
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the transglycosylases involved in the late stages of peptidoglycan biosynthesis. Members tend to be small, about 240 amino acids in length, and consist almost entirely of a domain described by pfam00912 for transglycosylases. Species with this protein will have several other transglycosylases as well. All species with this protein are Proteobacteria that produce murein (peptidoglycan). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273951 [Multi-domain] Cd Length: 224 Bit Score: 114.10 E-value: 1.43e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 53 AIIASENRSFYKDGGIDLKGIGRAIIHNVTS-KGRWGGSTITQQYAERYYLGETKTYLGKLHEAILALKIAQTQDKNTVL 131
Cdd:TIGR02070 70 AVIASEDAKFVEHHGFDWEAIQDALEKNEKSgKVVRGGSTISQQLAKNLFLWSGRSYLRKGLEAWATWMLETWWSKQRIL 149
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 514588806 132 CNYMNTIYLGRGAYGIQAAAKAYFGVEAKDLTLSQAAMLAGIIPAPSSWD 181
Cdd:TIGR02070 150 EVYLNSVEWGNGVFGAEAAARYYFKRSASNLTRGQAARLAAVLPNPKYYD 199
|
|
| Transpeptidase |
pfam00905 |
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ... |
294-553 |
1.50e-24 |
|
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain] Cd Length: 296 Bit Score: 104.42 E-value: 1.50e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 294 GAMSVNPKDGSIISVYAGDDYLSKP-----LNNATQALYEPGSTMKPFALIGAIQAGT-NLNTLFNGNTGLKFKGieKPV 367
Cdd:pfam00905 2 SAVVLDPKTGEVLAMVGKPSYDPNGfigplRNRAVTSRYEPGSTFKPFTALAALDNGVlKPDETIFDWPGKQQGG--KSI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 368 NNFANTNWGMINLYKATANSVNTPFMALQEKLGQK---------------GVANTAVMAGLNAQRVNGKNPFTVLGNDPV 432
Cdd:pfam00905 80 GDWNQDQVGIGTLRQALEYSSNWYMQKLAQKLGADklrsylkkfgygnktGIGLPGENAGYLTPYWLEGATASFGIGLTI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 433 HISEIARAYSTIANQGRRPDLHIVSSVknpdgkEFYRAPTV-GKQVFAAADMALAIKAMQGVVQYGTSPEVRGV-GKPIA 510
Cdd:pfam00905 160 TPLQQAQAYAAIANGGKLVPPHLVKSI------EDKVDPKVlNKLPISKSTAEKVKDMLRLVVNDGTGTGTAAVpGYKVA 233
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 514588806 511 GKSGTA-----------NDASACSFVGFTPSVLTVFAI-----WNPDAQGNPLPVPTFR 553
Cdd:pfam00905 234 GKTGTAqvagpkgggyyDGAQIGWFVGYAPADNPKYAFavlidDPKRYYGGKVAAPIFK 292
|
|
| PRK11240 |
PRK11240 |
penicillin-binding protein 1C; Provisional |
48-449 |
7.61e-17 |
|
penicillin-binding protein 1C; Provisional
Pssm-ID: 183049 [Multi-domain] Cd Length: 772 Bit Score: 84.75 E-value: 7.61e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 48 PYVGNAIIASENRSFYKDGGIDLKGIGRAIIHNVTSkGRW--GGSTITQQYAeRYYLGETKTYLGKLHEAILALKIAQTQ 125
Cdd:PRK11240 72 PRYLEALINYEDRWFWKHPGVNPFSVARAAWQDLTS-GRVisGGSTLTMQVA-RLLDPHPRTFGGKIRQLWRALQLEWHL 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 126 DKNTVLcnymnTIYLGRGAYG-----IQAAAKAYFGVEAKDLTLSQAAMLAGIIPAPSSWDPAIMPKEANMRFKRVLRIM 200
Cdd:PRK11240 150 SKREIL-----TLYLNRAPFGgtlqgIGAASWAYLGKSPANLSYAEAALLAVLPQAPSRLRPDRWPERAEAARNKVLERM 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 201 LKDKYITSEEYKNAK----------MPQtinqtkqnmyagpqgyLLQMVRSELTSGGAFTKedldtggyrIITTIDKAKQ 270
Cdd:PRK11240 225 AEQGVWSAEQVKESReepvwlaprqMPQ----------------LAPLFARMMLGKSKSDK---------IVTTLDAGLQ 279
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 271 ----DLMFNVASPTAGARGITPQGVQTGAMSVNPKDGSI----ISVYAGDDYLSkplnnatqALYEPGSTMKPFALIGAI 342
Cdd:PRK11240 280 rrleDLALNWKGRLPPRSSLAMIVVDHTDMAVRGWVGSVdlndDSRFGHVDMVN--------AIRSPGSVLKPFVYGLAL 351
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 343 QAGtnlntLFNGNTGL-----KFkGIEKPvNNFANTNWGMINLYKATANSVNTPFMALQEKLGQKGVANTAVMAGLNAQR 417
Cdd:PRK11240 352 DDG-----LIHPASLLqdvprRT-GDYRP-GNFDSGFHGPVSMSEALVRSLNLPAVQVLEAYGPKRFAAKLRNVGLPLYL 424
|
410 420 430
....*....|....*....|....*....|....
gi 514588806 418 VNGKNP--FTVLGNDPVHISEIARAYSTIANQGR 449
Cdd:PRK11240 425 PAGAEPnlSLILGGAGARLEDMVAAYSAFARHGK 458
|
|
| pbp2_mrdA |
TIGR03423 |
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ... |
258-516 |
6.42e-16 |
|
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 274573 [Multi-domain] Cd Length: 592 Bit Score: 81.42 E-value: 6.42e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 258 GYRIITTIDKAKQDLMFNVASPTAGArgitpqgvqtgAMSVNPKDGSI-----------------ISvyaGDDY------ 314
Cdd:TIGR03423 225 GKDLVLTIDARLQQAAEKALGGRRGA-----------VVVMDPRTGEIlamvstpsfdpnlfvdgIS---SKDYkallnd 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 315 LSKPLNN-ATQALYEPGSTMKPFALIGAIQAGT-NLNTLFNGNTGLKFKGieKPVNNFANTNWGMINLYKATANSVNTPF 392
Cdd:TIGR03423 291 PDRPLLNrAIQGVYPPGSTFKPVVALAALEEGViTPETRIYCPGYFQLGG--RRFRCWKRGGHGRVDLRKAIEESCDVYF 368
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 393 --MALQ---EK---------LGQK-GVANTAVMAGLN-----AQRVNGKNPFtvlGNDPVHIS-----------EIARAY 441
Cdd:TIGR03423 369 yqLALRlgiDKiaeyakrfgFGQKtGIDLPGEKSGLVpsrewKRKRFGQPWY---PGDTLNVSigqgyvlvtplQLAVAT 445
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 442 STIANQGRRPDLHIVSSVKNPDGKEFYR--APTVGKQVFAAADMALAIKAMQGVVQ--YGTSPEVR-GVGKPIAGKSGTA 516
Cdd:TIGR03423 446 AALANGGKLYKPHLVKSIEDPDGGVVRRtePEVLRPLPISPENLDVVREGMRDVVNgpGGTARRARlGLPYKMAGKTGTA 525
|
|
| strep_PBP2X |
NF038271 |
penicillin-binding protein PBP2X; |
289-520 |
4.32e-06 |
|
penicillin-binding protein PBP2X;
Pssm-ID: 468442 [Multi-domain] Cd Length: 748 Bit Score: 50.01 E-value: 4.32e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 289 QGVQTGAMSVNPKDGSIISV-----YAGD--DYLSKPLNNATQALY----EPGSTMKPFALIGAIQAGT-NLNTLFNGNT 356
Cdd:NF038271 282 KGKYASATLVNAKTGEILATtqrptYNADtkEGLDKKDLNWNNLLYqtnyEPGSTMKVMTLASAIDNGTfNPNETYSNSN 361
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 357 GLKFKGIEkpVNNFaNTNWGM-----INLYKATANSVNTPFMALQEKLGQK-----------GVANTAVMAGLNAQRVNG 420
Cdd:NF038271 362 GLTIADAT--INDW-DVNEGLstgqyMTYAQGFAYSSNVGMTLLEQKMGDDkwlnylskfkfGLPTRFGMGDESSGILPS 438
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514588806 421 KNPFTV----LGND-PVHISEIARAYSTIANQGRRPDLHIVSSVKNPDGKEFYRAPT--VGKQVFAAAdmalAIKAMQGV 493
Cdd:NF038271 439 DNIVTIamssFGQGiSVTQVQMLRAFSAISNDGVMLEPKFISAIYDPNTGTARKSKKevVGKPVSKDA----ASQTRNYM 514
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 514588806 494 VQYGTSPEV-----RGVGKPI--------AGKSGTANDAS 520
Cdd:NF038271 515 VTVGTDPYYgtlysKTTGGPIiqvgnysvAVKSGTAQIAK 554
|
|
| PRK10795 |
PRK10795 |
penicillin-binding protein 2; Provisional |
317-392 |
5.64e-04 |
|
penicillin-binding protein 2; Provisional
Pssm-ID: 236761 [Multi-domain] Cd Length: 634 Bit Score: 43.22 E-value: 5.64e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 514588806 317 KPL-NNATQALYEPGSTMKPFALIGAIQAGT-NLNTLFNGNTGLKFKGIEKPVNNFANTNWGMINLYKATANSVNTPF 392
Cdd:PRK10795 316 RPLiNRATQGVYPPASTVKPYVAVSALSAGViTRNTSLFDPGWWQLPGSEKRYRDWKKWGHGRLNVTKSLEESADTFF 393
|
|
| |
