|
Name |
Accession |
Description |
Interval |
E-value |
| RTX_toxin |
NF033943 |
RTX family hemolysin; RTX family toxin are secreted from the bacteria and inserted into the ... |
49-990 |
0e+00 |
|
RTX family hemolysin; RTX family toxin are secreted from the bacteria and inserted into the membranes of infected cells, causing host cell rupture.
Pssm-ID: 468257 [Multi-domain] Cd Length: 875 Bit Score: 1471.83 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 534599821 49 LILLIPKDYKGQ-GSSLNDLVRTADELGIEVQYDEKNGTAITKQVFGTAEKLIGLTERGVTIFAPQLDKLLQKYQKAGNK 127
Cdd:NF033943 1 LILLIPKDYDGQkGNGLNDLVKAADELGIEVQREERNNTAIAKKSFGTAEKLLGLTERGVVIFAPQLDKLLQKYSKIGNG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 534599821 128 LGGSAENIGDNLGKAGSVLSTFQNFLGTALSSMKIDELIKKqksGSNVSSSELAKASIELINQLVDTAASINNNVNSFSQ 207
Cdd:NF033943 81 LGSSAENIGNNLGKAQTVLSTIQSFLGTALAGMELDELIKK---GEDVSQLELAKASIELINELVDNIASSNQTIDAFSE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 534599821 208 QLNKLGSVLSNTKHLNGVGNKLQNLPNLDNIGAGLDTVSGILSAISASFILSNADADTGTKAAAGVELTTKVLGNVGKGI 287
Cdd:NF033943 158 QLNKLGSLLSNAKGLGGLGNKLQNLPNLSKAGLGLDVISGLLSGISAGFILADKNASTGTKVAAGFELTNQVLGNVTKAV 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 534599821 288 SQYIIAQRAAQGLSTSAAAAGLIASVVTLAISPLSFLSIADKFKRANKIEEYSQRFKKLGYDGDSLLAAFHKETGAIDAS 367
Cdd:NF033943 238 SSYILAQRVAAGLSTTGAVAALIASAVSLAISPLAFLSIADKFNRAKQLEEYSERFKKLGYDGDSLLAEFQRETGTIDAS 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 534599821 368 LTTISTVLASVSSGISAAATTSLVGAPVSALVGAVTGIISGILEASKQAMFEHVASKMADVIAEWEKKHGKNYFENGYDA 447
Cdd:NF033943 318 LTTINTALSAISAGVSAAAAGSLVGAPIALLVSGITGLISGILEASKQAMFEHVANKLANKIAEWEKKNGKNYFENGYDA 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 534599821 448 RHAAFLEDNFKILSQYNKEYSVERSVLITQQHWDTLIGELAGVTRNGDKTLSGKSYIDYYEEGKRLEKKPDEFQKQVFDP 527
Cdd:NF033943 398 RHAAFLEDNFKLLSSLNKEYQVERAVAITQQRWDENIGELAGITKNGDKISSGKAYVDYFEEGKRLEKKPDEFSKVVFDP 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 534599821 528 LKGNIDLSDSKSSTLLKFVTPLLTPGEEIRERRQSGKYEYITELLVKGVDKWTVKGVQDKGSVYDYSNLIQHASVGNNQY 607
Cdd:NF033943 478 LKGIIDISNSKKSTLLKFVTPLLTPGEESRERKQSGKYEYITKLVVNGVDKWTVKGVGNAGSVYDYSNLIQHAAIESGKY 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 534599821 608 REIRIESHLGDGDDKVFLSAGSANIYAGKGHDVVYYDKTDTGYLTIDGTKATEAGNYTVTRVLGGDVKILQEVVKEQEVS 687
Cdd:NF033943 558 REIRIISNLGAGNDKVFVGAGSSNIDAGEGHDRVYYSKTDTGYLTIDGTKATEAGSYTVTRELGGDVKILHEVVKEQETS 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 534599821 688 VGKRTEKTQYRSYEFtHINGKNLTETDNLYSVEELIGTTRADKFFGSKFTDIFHGADGDDHIEGNDGNDRLYgdkgndtl 767
Cdd:NF033943 638 VGKRTEKIQYRDYEL-RSGGYGYTATDTLKSVEEIIGSNRNDKFKGSKFNDIFHGADGDDTIEGNDGDDRLY-------- 708
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 534599821 768 rggngddqlyggdgndkliggtgnnylnggdgddelqvqgnslaknvlsGGKGNDKLYGSEGADLLDGGEGNDLLKGGYG 847
Cdd:NF033943 709 -------------------------------------------------GGKGDDKLYGGEGDDLLDGGEGNDYLNGGYG 739
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 534599821 848 NDIYRYLSGYGHHIIDDDGGKDDKLSLADIDFRDVAFRREDNDLIMYKAEGNVlsighKNGITFRNWFEKESGDISNHQI 927
Cdd:NF033943 740 NDIYIYRKGYGNHTIYDSGGKNDKLSLSDISLSDLTFKRVGNDLIINKNDNGV-----KNGITIKNWFKKESGNKKNHKI 814
|
890 900 910 920 930 940
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 534599821 928 EQIFDKDGRVITPDSLKKALEYQqsNNKASYVYGNDALAYGSQDNLNPLINEISKIISAAGNF 990
Cdd:NF033943 815 EQIIDKDGRVITSDQIDKLLKKK--NGKISYILLSKLADNYNESNLSSLANSLSKIISSAGSF 875
|
|
| RTX |
pfam02382 |
N-terminal domain in RTX protein; The RTX family of bacterial toxins are a group of cytolysins ... |
292-600 |
1.03e-96 |
|
N-terminal domain in RTX protein; The RTX family of bacterial toxins are a group of cytolysins and cytotoxins that have RTX (Repeat in ToXin repeats) pfam00353. This Pfam family represents a presumed domain which in some of these proteins.
Pssm-ID: 396797 Cd Length: 312 Bit Score: 308.27 E-value: 1.03e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 534599821 292 IAQRAAQGLSTSAAAAGLI---ASVVTLAISPLSFLSIADKFKRANKIEEYSQRFKKLGYDGDSLLAAFHKETGAIDASL 368
Cdd:pfam02382 1 LAQRAAAGLATTGAVAVLIlgiTASLALAISPLEWAAFAQKFDYADDLDKLAQEFSDFGYEGDGLLAELLRGKGTIEASF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 534599821 369 TTISTVLASVSSGISAAATTSLVGAPVSALVGAVTGIISGILEASKQAMFEHVASKMADVIAEWEKKhGKNYFENGYDAR 448
Cdd:pfam02382 81 YAISTALGVVSGGVSAAAAASGVGAPIALLVAGITGGISGILEASKQAMLEKVANRYAEKIRAKNNG-VQAYFENSFDAR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 534599821 449 HAAFLEDNFKILSQYNKEYSVERSVLITQQHWDTLIGELAGVTRNGDKTLSGKSYIDYYEEGKRLEKKPDEFQKQVFDPL 528
Cdd:pfam02382 160 HEALLEDNTKFLAELIKELNADRVIALGQQQWDANDGELAGISKLGGELKSGKAYVDAFEEGAKLEAGSWNTENIQLDAA 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 534599821 529 KGNIDLS--DSKSSTLLKFVTPLLTPGEEIRERRQSGKYEYITELLVKGVDKWTVKGvQDKGSVYDYSNLIQHA 600
Cdd:pfam02382 240 TGVIDISnvNGAKTQALTFTTPLLAAGTETRSRVHTGKNEYITTLKINRLKGWTIKD-GGANSTFDLSKVVQKA 312
|
|
| COG2931 |
COG2931 |
Ca2+-binding protein, RTX toxin-related [Secondary metabolites biosynthesis, transport and ... |
722-879 |
2.97e-17 |
|
Ca2+-binding protein, RTX toxin-related [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 442175 [Multi-domain] Cd Length: 252 Bit Score: 82.65 E-value: 2.97e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 534599821 722 LIGTTRADKFFGSKFTDIFHGADGDDHIEGNDGNDRLYGDKGNDTLRGGNGDDQLYGGDGNDKLIGGTGNNYLNGGDGDD 801
Cdd:COG2931 106 GDGGGGNDTLTGGDGNDTLTGGAGDDTLYGGAGNDTLTGGAGNDTLYGGAGNDTLYGGAGNDTLDGGAGNDTLTGGAGND 185
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 534599821 802 elqvqgnslaknVLSGGKGNDKLYGSEGADLLDGGEGNDLLKGGYGNDIYRYLSGYGHHIIDDDGGKDDKLSLADIDF 879
Cdd:COG2931 186 ------------TLTGGAGNDTLDGGGGDDTLGGGGGDDGLDGGDGDDGLGGGGGDDTLGGGGGGDGGGGGGGDDGLG 251
|
|
| HemolysinCabind |
pfam00353 |
RTX calcium-binding nonapeptide repeat (4 copies); |
751-785 |
3.50e-09 |
|
RTX calcium-binding nonapeptide repeat (4 copies);
Pssm-ID: 459777 [Multi-domain] Cd Length: 36 Bit Score: 52.83 E-value: 3.50e-09
10 20 30
....*....|....*....|....*....|....*
gi 534599821 751 GNDGNDRLYGDKGNDTLRGGNGDDQLYGGDGNDKL 785
Cdd:pfam00353 2 GGDGNDTLVGGAGNDTIYGGAGNDTLDGGAGNDTL 36
|
|
| HemolysinCabind |
pfam00353 |
RTX calcium-binding nonapeptide repeat (4 copies); |
769-803 |
9.95e-08 |
|
RTX calcium-binding nonapeptide repeat (4 copies);
Pssm-ID: 459777 [Multi-domain] Cd Length: 36 Bit Score: 48.97 E-value: 9.95e-08
10 20 30
....*....|....*....|....*....|....*
gi 534599821 769 GGNGDDQLYGGDGNDKLIGGTGNNYLNGGDGDDEL 803
Cdd:pfam00353 2 GGDGNDTLVGGAGNDTIYGGAGNDTLDGGAGNDTL 36
|
|
| MARTX_Nterm |
NF012221 |
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ... |
736-830 |
2.35e-03 |
|
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.
Pssm-ID: 467957 [Multi-domain] Cd Length: 1848 Bit Score: 42.13 E-value: 2.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 534599821 736 FTDIFHGADGDDHIEGNDGNDRLYGDKGNDTLRGGNGDDQLYGGDGNDKLIGGTGnnYLNGGDGDDELQVQGNSLAKNVL 815
Cdd:NF012221 13 FTGNYSADDGNNDIVAIGFGGIIHAYGGDDTITVGSIGATVYTGSGNDTVVGGAG--YLKVVDTSGNLTVKGAAGYADIN 90
|
90
....*....|....*
gi 534599821 816 SGGKGNDKLYGSEGA 830
Cdd:NF012221 91 KSGDGNVSFTGAAGG 105
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| RTX_toxin |
NF033943 |
RTX family hemolysin; RTX family toxin are secreted from the bacteria and inserted into the ... |
49-990 |
0e+00 |
|
RTX family hemolysin; RTX family toxin are secreted from the bacteria and inserted into the membranes of infected cells, causing host cell rupture.
Pssm-ID: 468257 [Multi-domain] Cd Length: 875 Bit Score: 1471.83 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 534599821 49 LILLIPKDYKGQ-GSSLNDLVRTADELGIEVQYDEKNGTAITKQVFGTAEKLIGLTERGVTIFAPQLDKLLQKYQKAGNK 127
Cdd:NF033943 1 LILLIPKDYDGQkGNGLNDLVKAADELGIEVQREERNNTAIAKKSFGTAEKLLGLTERGVVIFAPQLDKLLQKYSKIGNG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 534599821 128 LGGSAENIGDNLGKAGSVLSTFQNFLGTALSSMKIDELIKKqksGSNVSSSELAKASIELINQLVDTAASINNNVNSFSQ 207
Cdd:NF033943 81 LGSSAENIGNNLGKAQTVLSTIQSFLGTALAGMELDELIKK---GEDVSQLELAKASIELINELVDNIASSNQTIDAFSE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 534599821 208 QLNKLGSVLSNTKHLNGVGNKLQNLPNLDNIGAGLDTVSGILSAISASFILSNADADTGTKAAAGVELTTKVLGNVGKGI 287
Cdd:NF033943 158 QLNKLGSLLSNAKGLGGLGNKLQNLPNLSKAGLGLDVISGLLSGISAGFILADKNASTGTKVAAGFELTNQVLGNVTKAV 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 534599821 288 SQYIIAQRAAQGLSTSAAAAGLIASVVTLAISPLSFLSIADKFKRANKIEEYSQRFKKLGYDGDSLLAAFHKETGAIDAS 367
Cdd:NF033943 238 SSYILAQRVAAGLSTTGAVAALIASAVSLAISPLAFLSIADKFNRAKQLEEYSERFKKLGYDGDSLLAEFQRETGTIDAS 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 534599821 368 LTTISTVLASVSSGISAAATTSLVGAPVSALVGAVTGIISGILEASKQAMFEHVASKMADVIAEWEKKHGKNYFENGYDA 447
Cdd:NF033943 318 LTTINTALSAISAGVSAAAAGSLVGAPIALLVSGITGLISGILEASKQAMFEHVANKLANKIAEWEKKNGKNYFENGYDA 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 534599821 448 RHAAFLEDNFKILSQYNKEYSVERSVLITQQHWDTLIGELAGVTRNGDKTLSGKSYIDYYEEGKRLEKKPDEFQKQVFDP 527
Cdd:NF033943 398 RHAAFLEDNFKLLSSLNKEYQVERAVAITQQRWDENIGELAGITKNGDKISSGKAYVDYFEEGKRLEKKPDEFSKVVFDP 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 534599821 528 LKGNIDLSDSKSSTLLKFVTPLLTPGEEIRERRQSGKYEYITELLVKGVDKWTVKGVQDKGSVYDYSNLIQHASVGNNQY 607
Cdd:NF033943 478 LKGIIDISNSKKSTLLKFVTPLLTPGEESRERKQSGKYEYITKLVVNGVDKWTVKGVGNAGSVYDYSNLIQHAAIESGKY 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 534599821 608 REIRIESHLGDGDDKVFLSAGSANIYAGKGHDVVYYDKTDTGYLTIDGTKATEAGNYTVTRVLGGDVKILQEVVKEQEVS 687
Cdd:NF033943 558 REIRIISNLGAGNDKVFVGAGSSNIDAGEGHDRVYYSKTDTGYLTIDGTKATEAGSYTVTRELGGDVKILHEVVKEQETS 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 534599821 688 VGKRTEKTQYRSYEFtHINGKNLTETDNLYSVEELIGTTRADKFFGSKFTDIFHGADGDDHIEGNDGNDRLYgdkgndtl 767
Cdd:NF033943 638 VGKRTEKIQYRDYEL-RSGGYGYTATDTLKSVEEIIGSNRNDKFKGSKFNDIFHGADGDDTIEGNDGDDRLY-------- 708
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 534599821 768 rggngddqlyggdgndkliggtgnnylnggdgddelqvqgnslaknvlsGGKGNDKLYGSEGADLLDGGEGNDLLKGGYG 847
Cdd:NF033943 709 -------------------------------------------------GGKGDDKLYGGEGDDLLDGGEGNDYLNGGYG 739
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 534599821 848 NDIYRYLSGYGHHIIDDDGGKDDKLSLADIDFRDVAFRREDNDLIMYKAEGNVlsighKNGITFRNWFEKESGDISNHQI 927
Cdd:NF033943 740 NDIYIYRKGYGNHTIYDSGGKNDKLSLSDISLSDLTFKRVGNDLIINKNDNGV-----KNGITIKNWFKKESGNKKNHKI 814
|
890 900 910 920 930 940
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 534599821 928 EQIFDKDGRVITPDSLKKALEYQqsNNKASYVYGNDALAYGSQDNLNPLINEISKIISAAGNF 990
Cdd:NF033943 815 EQIIDKDGRVITSDQIDKLLKKK--NGKISYILLSKLADNYNESNLSSLANSLSKIISSAGSF 875
|
|
| RTX |
pfam02382 |
N-terminal domain in RTX protein; The RTX family of bacterial toxins are a group of cytolysins ... |
292-600 |
1.03e-96 |
|
N-terminal domain in RTX protein; The RTX family of bacterial toxins are a group of cytolysins and cytotoxins that have RTX (Repeat in ToXin repeats) pfam00353. This Pfam family represents a presumed domain which in some of these proteins.
Pssm-ID: 396797 Cd Length: 312 Bit Score: 308.27 E-value: 1.03e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 534599821 292 IAQRAAQGLSTSAAAAGLI---ASVVTLAISPLSFLSIADKFKRANKIEEYSQRFKKLGYDGDSLLAAFHKETGAIDASL 368
Cdd:pfam02382 1 LAQRAAAGLATTGAVAVLIlgiTASLALAISPLEWAAFAQKFDYADDLDKLAQEFSDFGYEGDGLLAELLRGKGTIEASF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 534599821 369 TTISTVLASVSSGISAAATTSLVGAPVSALVGAVTGIISGILEASKQAMFEHVASKMADVIAEWEKKhGKNYFENGYDAR 448
Cdd:pfam02382 81 YAISTALGVVSGGVSAAAAASGVGAPIALLVAGITGGISGILEASKQAMLEKVANRYAEKIRAKNNG-VQAYFENSFDAR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 534599821 449 HAAFLEDNFKILSQYNKEYSVERSVLITQQHWDTLIGELAGVTRNGDKTLSGKSYIDYYEEGKRLEKKPDEFQKQVFDPL 528
Cdd:pfam02382 160 HEALLEDNTKFLAELIKELNADRVIALGQQQWDANDGELAGISKLGGELKSGKAYVDAFEEGAKLEAGSWNTENIQLDAA 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 534599821 529 KGNIDLS--DSKSSTLLKFVTPLLTPGEEIRERRQSGKYEYITELLVKGVDKWTVKGvQDKGSVYDYSNLIQHA 600
Cdd:pfam02382 240 TGVIDISnvNGAKTQALTFTTPLLAAGTETRSRVHTGKNEYITTLKINRLKGWTIKD-GGANSTFDLSKVVQKA 312
|
|
| COG2931 |
COG2931 |
Ca2+-binding protein, RTX toxin-related [Secondary metabolites biosynthesis, transport and ... |
722-879 |
2.97e-17 |
|
Ca2+-binding protein, RTX toxin-related [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 442175 [Multi-domain] Cd Length: 252 Bit Score: 82.65 E-value: 2.97e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 534599821 722 LIGTTRADKFFGSKFTDIFHGADGDDHIEGNDGNDRLYGDKGNDTLRGGNGDDQLYGGDGNDKLIGGTGNNYLNGGDGDD 801
Cdd:COG2931 106 GDGGGGNDTLTGGDGNDTLTGGAGDDTLYGGAGNDTLTGGAGNDTLYGGAGNDTLYGGAGNDTLDGGAGNDTLTGGAGND 185
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 534599821 802 elqvqgnslaknVLSGGKGNDKLYGSEGADLLDGGEGNDLLKGGYGNDIYRYLSGYGHHIIDDDGGKDDKLSLADIDF 879
Cdd:COG2931 186 ------------TLTGGAGNDTLDGGGGDDTLGGGGGDDGLDGGDGDDGLGGGGGDDTLGGGGGGDGGGGGGGDDGLG 251
|
|
| COG2931 |
COG2931 |
Ca2+-binding protein, RTX toxin-related [Secondary metabolites biosynthesis, transport and ... |
713-850 |
6.44e-17 |
|
Ca2+-binding protein, RTX toxin-related [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 442175 [Multi-domain] Cd Length: 252 Bit Score: 81.49 E-value: 6.44e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 534599821 713 TDNLYSVEELIGTTRADKFFGSKFTDIFHGADGDDHIEGNDGNDRLYGDKGNDTLRGGNGDDQLYGGDGNDKLIGGTGNN 792
Cdd:COG2931 79 GGGGGGDDTDGGGDGGDGGGGGTGDDTGDGGGGNDTLTGGDGNDTLTGGAGDDTLYGGAGNDTLTGGAGNDTLYGGAGND 158
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 534599821 793 YLNGGDGDDelqvqgnslaknVLSGGKGNDKLYGSEGADLLDGGEGNDLLKGGYGNDI 850
Cdd:COG2931 159 TLYGGAGND------------TLDGGAGNDTLTGGAGNDTLTGGAGNDTLDGGGGDDT 204
|
|
| RTX_C |
pfam08339 |
RTX C-terminal domain; This family describes the C-terminal region of various bacterial ... |
873-991 |
1.28e-10 |
|
RTX C-terminal domain; This family describes the C-terminal region of various bacterial haemolysins and leukotoxins, which belong to the RTX family of toxins. These are produced by various Gram negative bacteria, such as E. coli and Actinobacillus pleuropneumoniae. RTX toxins may interact with lipopolysaccharide (LPS) to functionally impair and eventually kill leukocytes. This region is found in association with the RTX N-terminal domain (pfam02382) and multiple hemolysin-type calcium-binding repeats (pfam00353).
Pssm-ID: 429930 Cd Length: 131 Bit Score: 60.30 E-value: 1.28e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 534599821 873 SLADIDFRDVAFRREDNDLIMYKAEGnvlsighKNGITFRNWFEKES-----GDISNHQIEQIFDKDGRVITPDSLKKAL 947
Cdd:pfam08339 1 AFSDANLSDLTFERVGNGLIIKKNDD-------SGSITFKNWFAALSrpnyhASGTDDKIEEIIGKNGRYITSEQVDKLL 73
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 534599821 948 EYQQSNNKASYVYGNDALAYGSQDNLNPLINEISKIISAAGNFD 991
Cdd:pfam08339 74 NNKQSGKITSSQLQQLAQNKSNMINSTDVANSLNKLISSMSGFG 117
|
|
| HemolysinCabind |
pfam00353 |
RTX calcium-binding nonapeptide repeat (4 copies); |
751-785 |
3.50e-09 |
|
RTX calcium-binding nonapeptide repeat (4 copies);
Pssm-ID: 459777 [Multi-domain] Cd Length: 36 Bit Score: 52.83 E-value: 3.50e-09
10 20 30
....*....|....*....|....*....|....*
gi 534599821 751 GNDGNDRLYGDKGNDTLRGGNGDDQLYGGDGNDKL 785
Cdd:pfam00353 2 GGDGNDTLVGGAGNDTIYGGAGNDTLDGGAGNDTL 36
|
|
| HemolysinCabind |
pfam00353 |
RTX calcium-binding nonapeptide repeat (4 copies); |
759-794 |
2.02e-08 |
|
RTX calcium-binding nonapeptide repeat (4 copies);
Pssm-ID: 459777 [Multi-domain] Cd Length: 36 Bit Score: 50.90 E-value: 2.02e-08
10 20 30
....*....|....*....|....*....|....*.
gi 534599821 759 YGDKGNDTLRGGNGDDQLYGGDGNDKLIGGTGNNYL 794
Cdd:pfam00353 1 YGGDGNDTLVGGAGNDTIYGGAGNDTLDGGAGNDTL 36
|
|
| HemolysinCabind |
pfam00353 |
RTX calcium-binding nonapeptide repeat (4 copies); |
741-776 |
2.65e-08 |
|
RTX calcium-binding nonapeptide repeat (4 copies);
Pssm-ID: 459777 [Multi-domain] Cd Length: 36 Bit Score: 50.51 E-value: 2.65e-08
10 20 30
....*....|....*....|....*....|....*.
gi 534599821 741 HGADGDDHIEGNDGNDRLYGDKGNDTLRGGNGDDQL 776
Cdd:pfam00353 1 YGGDGNDTLVGGAGNDTIYGGAGNDTLDGGAGNDTL 36
|
|
| HemolysinCabind |
pfam00353 |
RTX calcium-binding nonapeptide repeat (4 copies); |
769-803 |
9.95e-08 |
|
RTX calcium-binding nonapeptide repeat (4 copies);
Pssm-ID: 459777 [Multi-domain] Cd Length: 36 Bit Score: 48.97 E-value: 9.95e-08
10 20 30
....*....|....*....|....*....|....*
gi 534599821 769 GGNGDDQLYGGDGNDKLIGGTGNNYLNGGDGDDEL 803
Cdd:pfam00353 2 GGDGNDTLVGGAGNDTIYGGAGNDTLDGGAGNDTL 36
|
|
| Peptidase_M10_C |
pfam08548 |
Peptidase M10 serralysin C terminal; Serralysins are peptidases related to mammalian matrix ... |
740-856 |
8.48e-07 |
|
Peptidase M10 serralysin C terminal; Serralysins are peptidases related to mammalian matrix metallopeptidases (MMPs). The peptidase unit is found at the N terminal while this domain at the C terminal forms a corkscrew and is thought to be important for secretion of the protein through the bacterial cell wall. This domain contains the calcium ion binding domain pfam00353.
Pssm-ID: 430067 [Multi-domain] Cd Length: 222 Bit Score: 51.22 E-value: 8.48e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 534599821 740 FHGADGDDHIEGNDGNDRL----YGDKGNDTLR-GGNGDDQ---LYGGDGNDklIGG-TGN----------NYLnGGDGD 800
Cdd:pfam08548 14 FNSNTGRDFYTATDASSKLifsvWDAGGNDTFDfSGYSQNQrinLNEGSFSD--VGGlKGNvsiahgvtieNAI-GGSGN 90
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 534599821 801 DELQvqGNSlAKNVLSGGKGNDKLYGSEGADLLDGGEgndllkggyGNDIYRYLSG 856
Cdd:pfam08548 91 DVLI--GND-ADNILKGGAGNDILYGGGGADQLWGGA---------GNDIFVYASA 134
|
|
| Peptidase_M10_C |
pfam08548 |
Peptidase M10 serralysin C terminal; Serralysins are peptidases related to mammalian matrix ... |
751-803 |
1.07e-06 |
|
Peptidase M10 serralysin C terminal; Serralysins are peptidases related to mammalian matrix metallopeptidases (MMPs). The peptidase unit is found at the N terminal while this domain at the C terminal forms a corkscrew and is thought to be important for secretion of the protein through the bacterial cell wall. This domain contains the calcium ion binding domain pfam00353.
Pssm-ID: 430067 [Multi-domain] Cd Length: 222 Bit Score: 50.83 E-value: 1.07e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 534599821 751 GNDGNDRLYGDKGNDTLRGGNGDDQLYGGDGNDKLIGGTGNNYLNGGDGDDEL 803
Cdd:pfam08548 86 GGSGNDVLIGNDADNILKGGAGNDILYGGGGADQLWGGAGNDIFVYASAKDSL 138
|
|
| HemolysinCabind |
pfam00353 |
RTX calcium-binding nonapeptide repeat (4 copies); |
732-767 |
3.74e-06 |
|
RTX calcium-binding nonapeptide repeat (4 copies);
Pssm-ID: 459777 [Multi-domain] Cd Length: 36 Bit Score: 44.35 E-value: 3.74e-06
10 20 30
....*....|....*....|....*....|....*.
gi 534599821 732 FGSKFTDIFHGADGDDHIEGNDGNDRLYGDKGNDTL 767
Cdd:pfam00353 1 YGGDGNDTLVGGAGNDTIYGGAGNDTLDGGAGNDTL 36
|
|
| HemolysinCabind |
pfam00353 |
RTX calcium-binding nonapeptide repeat (4 copies); |
777-824 |
9.68e-06 |
|
RTX calcium-binding nonapeptide repeat (4 copies);
Pssm-ID: 459777 [Multi-domain] Cd Length: 36 Bit Score: 43.20 E-value: 9.68e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 534599821 777 YGGDGNDKLIGGTGNNYLNGGDGDDelqvqgnslaknVLSGGKGNDKL 824
Cdd:pfam00353 1 YGGDGNDTLVGGAGNDTIYGGAGND------------TLDGGAGNDTL 36
|
|
| HemolysinCabind |
pfam00353 |
RTX calcium-binding nonapeptide repeat (4 copies); |
817-850 |
1.61e-05 |
|
RTX calcium-binding nonapeptide repeat (4 copies);
Pssm-ID: 459777 [Multi-domain] Cd Length: 36 Bit Score: 42.42 E-value: 1.61e-05
10 20 30
....*....|....*....|....*....|....
gi 534599821 817 GGKGNDKLYGSEGADLLDGGEGNDLLKGGYGNDI 850
Cdd:pfam00353 2 GGDGNDTLVGGAGNDTIYGGAGNDTLDGGAGNDT 35
|
|
| HemolysinCabind |
pfam00353 |
RTX calcium-binding nonapeptide repeat (4 copies); |
796-842 |
2.85e-05 |
|
RTX calcium-binding nonapeptide repeat (4 copies);
Pssm-ID: 459777 [Multi-domain] Cd Length: 36 Bit Score: 42.04 E-value: 2.85e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 534599821 796 GGDGDDelqvqgnslaknVLSGGKGNDKLYGSEGADLLDGGEGNDLL 842
Cdd:pfam00353 2 GGDGND------------TLVGGAGNDTIYGGAGNDTLDGGAGNDTL 36
|
|
| HemolysinCabind |
pfam00353 |
RTX calcium-binding nonapeptide repeat (4 copies); |
825-856 |
1.70e-03 |
|
RTX calcium-binding nonapeptide repeat (4 copies);
Pssm-ID: 459777 [Multi-domain] Cd Length: 36 Bit Score: 37.03 E-value: 1.70e-03
10 20 30
....*....|....*....|....*....|..
gi 534599821 825 YGSEGADLLDGGEGNDLLKGGYGNDIYRYLSG 856
Cdd:pfam00353 1 YGGDGNDTLVGGAGNDTIYGGAGNDTLDGGAG 32
|
|
| MARTX_Nterm |
NF012221 |
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ... |
736-830 |
2.35e-03 |
|
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.
Pssm-ID: 467957 [Multi-domain] Cd Length: 1848 Bit Score: 42.13 E-value: 2.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 534599821 736 FTDIFHGADGDDHIEGNDGNDRLYGDKGNDTLRGGNGDDQLYGGDGNDKLIGGTGnnYLNGGDGDDELQVQGNSLAKNVL 815
Cdd:NF012221 13 FTGNYSADDGNNDIVAIGFGGIIHAYGGDDTITVGSIGATVYTGSGNDTVVGGAG--YLKVVDTSGNLTVKGAAGYADIN 90
|
90
....*....|....*
gi 534599821 816 SGGKGNDKLYGSEGA 830
Cdd:NF012221 91 KSGDGNVSFTGAAGG 105
|
|
| |
