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Conserved domains on  [gi|534608572|gb|EQN65601|]
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hypothetical protein G696_00231 [Escherichia coli HVH 20 (4-5865042)]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
IS66_access_TnpA super family cl45815
IS66-like element accessory protein TnpA;
2-57 4.00e-17

IS66-like element accessory protein TnpA;


The actual alignment was detected with superfamily member NF038385:

Pssm-ID: 439678 [Multi-domain]  Cd Length: 190  Bit Score: 70.90  E-value: 4.00e-17
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 534608572   2 DKPTDWRSGTRRIFSNEFKLHMVELASKPNANVAQLAREHGVDNNLIFKWLRLWQR 57
Cdd:NF038385  76 TRPVVWKKIRRPNFSREFKIRLVEQTLQPGACVAQIARENGINDNLLFNWRHLYRN 131
 
Name Accession Description Interval E-value
IS66_access_TnpA NF038385
IS66-like element accessory protein TnpA;
2-57 4.00e-17

IS66-like element accessory protein TnpA;


Pssm-ID: 439678 [Multi-domain]  Cd Length: 190  Bit Score: 70.90  E-value: 4.00e-17
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 534608572   2 DKPTDWRSGTRRIFSNEFKLHMVELASKPNANVAQLAREHGVDNNLIFKWLRLWQR 57
Cdd:NF038385  76 TRPVVWKKIRRPNFSREFKIRLVEQTLQPGACVAQIARENGINDNLLFNWRHLYRN 131
InsE COG2963
Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];
9-59 2.31e-12

Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442203 [Multi-domain]  Cd Length: 93  Bit Score: 56.47  E-value: 2.31e-12
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|.
gi 534608572  9 SGTRRIFSNEFKLHMVELASKPNANVAQLAREHGVDNNLIFKWLRLWQREG 59
Cdd:COG2963   2 SKKRRRYSPEFKAEAVRLVLEGGASVAEVARELGISPSTLYRWVRQYREGG 52
HTH_Tnp_1 pfam01527
Transposase; Transposase proteins are necessary for efficient DNA transposition. This family ...
 10-56 6.40e-08

Transposase; Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.


Pssm-ID: 426308 [Multi-domain]  Cd Length: 75  Bit Score: 44.65  E-value: 6.40e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 534608572  10 GTRRIFSNEFKLHMVELASKPNANVAQLAREHGVDNNLIFKWLRLWQ 56
Cdd:pfam01527  2 KKRRRFSEEFKLRAVKEVLEPGRTVKEVARRHGVSPNTLYQWRRQYE 48
transpos_IS3 NF033516
IS3 family transposase;
18-59 2.08e-06

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 42.94  E-value: 2.08e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 534608572  18 EFKLHMVELASKPNANVAQLAREHGVDNNLIFKWLRLWQREG 59
Cdd:NF033516   1 EFKLEAVREVLEGGKSVAEVARELGISPSTLYRWRKKYRGGG 42
PRK09413 PRK09413
IS2 repressor TnpA; Reviewed
 12-62 4.17e-03

IS2 repressor TnpA; Reviewed


Pssm-ID: 181833  Cd Length: 121  Bit Score: 33.24  E-value: 4.17e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 534608572  12 RRIFSNEFKLHMVELASKPNANVAQLAREHGVDNNLIFKWLRLWQrEGRIS 62
Cdd:PRK09413  10 RRRRTTQEKIAIVQQSFEPGMTVSLVARQHGVAASQLFLWRKQYQ-EGSLT 59
 
Name Accession Description Interval E-value
IS66_access_TnpA NF038385
IS66-like element accessory protein TnpA;
2-57 4.00e-17

IS66-like element accessory protein TnpA;


Pssm-ID: 439678 [Multi-domain]  Cd Length: 190  Bit Score: 70.90  E-value: 4.00e-17
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 534608572   2 DKPTDWRSGTRRIFSNEFKLHMVELASKPNANVAQLAREHGVDNNLIFKWLRLWQR 57
Cdd:NF038385  76 TRPVVWKKIRRPNFSREFKIRLVEQTLQPGACVAQIARENGINDNLLFNWRHLYRN 131
InsE COG2963
Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];
9-59 2.31e-12

Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442203 [Multi-domain]  Cd Length: 93  Bit Score: 56.47  E-value: 2.31e-12
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|.
gi 534608572  9 SGTRRIFSNEFKLHMVELASKPNANVAQLAREHGVDNNLIFKWLRLWQREG 59
Cdd:COG2963   2 SKKRRRYSPEFKAEAVRLVLEGGASVAEVARELGISPSTLYRWVRQYREGG 52
HTH_Tnp_1 pfam01527
Transposase; Transposase proteins are necessary for efficient DNA transposition. This family ...
 10-56 6.40e-08

Transposase; Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.


Pssm-ID: 426308 [Multi-domain]  Cd Length: 75  Bit Score: 44.65  E-value: 6.40e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 534608572  10 GTRRIFSNEFKLHMVELASKPNANVAQLAREHGVDNNLIFKWLRLWQ 56
Cdd:pfam01527  2 KKRRRFSEEFKLRAVKEVLEPGRTVKEVARRHGVSPNTLYQWRRQYE 48
transpos_IS3 NF033516
IS3 family transposase;
18-59 2.08e-06

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 42.94  E-value: 2.08e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 534608572  18 EFKLHMVELASKPNANVAQLAREHGVDNNLIFKWLRLWQREG 59
Cdd:NF033516   1 EFKLEAVREVLEGGKSVAEVARELGISPSTLYRWRKKYRGGG 42
PRK09413 PRK09413
IS2 repressor TnpA; Reviewed
 12-62 4.17e-03

IS2 repressor TnpA; Reviewed


Pssm-ID: 181833  Cd Length: 121  Bit Score: 33.24  E-value: 4.17e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 534608572  12 RRIFSNEFKLHMVELASKPNANVAQLAREHGVDNNLIFKWLRLWQrEGRIS 62
Cdd:PRK09413  10 RRRRTTQEKIAIVQQSFEPGMTVSLVARQHGVAASQLFLWRKQYQ-EGSLT 59
BrkDBD pfam09607
Brinker DNA-binding domain; This DNA-binding domain is the first approx. 100 residues of the ...
 10-53 8.15e-03

Brinker DNA-binding domain; This DNA-binding domain is the first approx. 100 residues of the N-terminal end of Brinker. The structure of this domain in complex with DNA consists of four alpha-helices that contain a helix-turn-helix DNA recognition motif specific for GC-rich DNA. The Brinker nuclear repressor is a major element of the Drosophila Decapentaplegic morphogen signalling pathway.


Pssm-ID: 462838 [Multi-domain]  Cd Length: 58  Bit Score: 31.25  E-value: 8.15e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 534608572  10 GTRRIFSNEFKLHMVELASKPN---ANVAQLAREHGVDNNLIFKWLR 53
Cdd:pfam09607  1 GMRHIFDAGFKLMVLESAENDNdckGNQRAAAKKFGIHEKNIQDWLK 47
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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