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Conserved domains on  [gi|535033303|gb|EQR80461|]
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hypothetical protein G795_04919 [Escherichia coli HVH 137 (4-2124971)]

Protein Classification

DotA/TraY family protein( domain architecture ID 10025058)

DotA/TraY family protein similar to conjugal transfer/type IV secretion protein DotA/TraY

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DotA_TraY TIGR04346
conjugal transfer/type IV secretion protein DotA/TraY; Members of this protein family include ...
38-669 2.31e-166

conjugal transfer/type IV secretion protein DotA/TraY; Members of this protein family include transfer protein TraY of IncI1 plasmid R64 and DotA (defect in organelle trafficking A) of Legionella pneumophila.


:

Pssm-ID: 275142  Cd Length: 652  Bit Score: 493.45  E-value: 2.31e-166
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535033303   38 LSRQALVTIFGDVVTNPLTAS--SNTIIGNLFMVFNAIIATMGIVWFLFIGIRHAVRTGHQGSVF-NNGRDVVGILSVVS 114
Cdd:TIGR04346   1 LSVQILDSLFGSVVNNPLGGSggPDTILGSIFGVFNLVILIVGSILLSYTIIAGLLNTAHDGELLgKKYSSVWTPLRTVI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535033303  115 GFLMIVPTASGWSLAQLVMLWGAsIMGIGSANIMVQTAAE--NIAEGYSMTVQPVHVSTRTAARGILEMELCKHAMNT-- 190
Cdd:TIGR04346  81 GIALLLPIAKGFSLIQLLVLWLA-VQGIGLANLVWSAGADalNFGGGVLVTTQPVQPKTAEVAKGLLESEVCRAADNVnk 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535033303  191 GLNDFNrTARSSTPPMSESSRTENGRYTV--TVSNGSAT-----CGSVSLSVKGNGsnKQSALAHFFNPFIETEYQGVLT 263
Cdd:TIGR04346 160 GSGAPN-LGPISKSSIGYSGAWSTGSTSYgyTLKFGNATgsvgiCGSVSFSFSGDD--AQSVNGAGLAPFTTGDLDSVCQ 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535033303  264 AQRSAMDTMLRDLDSAAQEFVSAYRTRRDTGNGNLPDIESRIQKAANRYEETVQKALPADNAETER---REQLKSYLTTY 340
Cdd:TIGR04346 237 AQQQALVTAISDLITAASEIANTIWQGASITGTALPEVAASIETAADAYEALVADALSAASSDQQAqikKENFATTAKEL 316
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535033303  341 GWVALGAWYQTFATANQRLEDLANRAPTVSGVSslgEAGDTEFLKEVKGAYQAQL----QNSPYTPALGTNTSSTEYRTA 416
Cdd:TIGR04346 317 GWASAGAWYWTISRLNQKVLAAANSLPTVTGPS---GSGLGSRFSGLFDAYIEALsqviLADAYATPAGTSALAGAEAVA 393
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535033303  417 EAAEPKSIIMKVWS--GENFADKIATSLSGTGT-SSDQLNPLIKMKNIGDYTMGITESIWAGYTTVRVLSTAGSNSVFGR 493
Cdd:TIGR04346 394 SAAEAGDNFSAIWKflRGLMSMWVGTSISFTSNeTSSGTNPLIAMKNIGDYLIGIAEATYGAGAVLGAVGSGVALGGVIA 473
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535033303  494 LV-NAVSGLSDAAKAFLEASAPPLYFLLFLLFCAGFSLSIYLPFIPFIFWMTGIGNWIVSVLIGCAAGPLWAATHLGTSQ 572
Cdd:TIGR04346 474 GFlGFVGGGAAALSGLLSAISFVLFPLALALFIMGLILAYYLPFIPFIIWMGAVVGWLILVVEAVVAAPLWALAHLLPEG 553
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535033303  573 DR--GSRAAYGYIYLIDSMIRPLLMVFGFFFASVAIVAGGTILNALFGAALVNVQADSLTGLFSIAGFLLIYARVCTTLV 650
Cdd:TIGR04346 554 DGlaGQRAGQGYLLLLSILLRPPLMVIGFFAAILLSDVIGTLLNKLFAIALANVQSGSVTGILGFIAMLVIYAVILFLLI 633
                         650
                  ....*....|....*....
gi 535033303  651 AAVFALQAYLPDHVINFLG 669
Cdd:TIGR04346 634 AKLFGLIHELPDHVLRWIG 652
 
Name Accession Description Interval E-value
DotA_TraY TIGR04346
conjugal transfer/type IV secretion protein DotA/TraY; Members of this protein family include ...
38-669 2.31e-166

conjugal transfer/type IV secretion protein DotA/TraY; Members of this protein family include transfer protein TraY of IncI1 plasmid R64 and DotA (defect in organelle trafficking A) of Legionella pneumophila.


Pssm-ID: 275142  Cd Length: 652  Bit Score: 493.45  E-value: 2.31e-166
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535033303   38 LSRQALVTIFGDVVTNPLTAS--SNTIIGNLFMVFNAIIATMGIVWFLFIGIRHAVRTGHQGSVF-NNGRDVVGILSVVS 114
Cdd:TIGR04346   1 LSVQILDSLFGSVVNNPLGGSggPDTILGSIFGVFNLVILIVGSILLSYTIIAGLLNTAHDGELLgKKYSSVWTPLRTVI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535033303  115 GFLMIVPTASGWSLAQLVMLWGAsIMGIGSANIMVQTAAE--NIAEGYSMTVQPVHVSTRTAARGILEMELCKHAMNT-- 190
Cdd:TIGR04346  81 GIALLLPIAKGFSLIQLLVLWLA-VQGIGLANLVWSAGADalNFGGGVLVTTQPVQPKTAEVAKGLLESEVCRAADNVnk 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535033303  191 GLNDFNrTARSSTPPMSESSRTENGRYTV--TVSNGSAT-----CGSVSLSVKGNGsnKQSALAHFFNPFIETEYQGVLT 263
Cdd:TIGR04346 160 GSGAPN-LGPISKSSIGYSGAWSTGSTSYgyTLKFGNATgsvgiCGSVSFSFSGDD--AQSVNGAGLAPFTTGDLDSVCQ 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535033303  264 AQRSAMDTMLRDLDSAAQEFVSAYRTRRDTGNGNLPDIESRIQKAANRYEETVQKALPADNAETER---REQLKSYLTTY 340
Cdd:TIGR04346 237 AQQQALVTAISDLITAASEIANTIWQGASITGTALPEVAASIETAADAYEALVADALSAASSDQQAqikKENFATTAKEL 316
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535033303  341 GWVALGAWYQTFATANQRLEDLANRAPTVSGVSslgEAGDTEFLKEVKGAYQAQL----QNSPYTPALGTNTSSTEYRTA 416
Cdd:TIGR04346 317 GWASAGAWYWTISRLNQKVLAAANSLPTVTGPS---GSGLGSRFSGLFDAYIEALsqviLADAYATPAGTSALAGAEAVA 393
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535033303  417 EAAEPKSIIMKVWS--GENFADKIATSLSGTGT-SSDQLNPLIKMKNIGDYTMGITESIWAGYTTVRVLSTAGSNSVFGR 493
Cdd:TIGR04346 394 SAAEAGDNFSAIWKflRGLMSMWVGTSISFTSNeTSSGTNPLIAMKNIGDYLIGIAEATYGAGAVLGAVGSGVALGGVIA 473
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535033303  494 LV-NAVSGLSDAAKAFLEASAPPLYFLLFLLFCAGFSLSIYLPFIPFIFWMTGIGNWIVSVLIGCAAGPLWAATHLGTSQ 572
Cdd:TIGR04346 474 GFlGFVGGGAAALSGLLSAISFVLFPLALALFIMGLILAYYLPFIPFIIWMGAVVGWLILVVEAVVAAPLWALAHLLPEG 553
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535033303  573 DR--GSRAAYGYIYLIDSMIRPLLMVFGFFFASVAIVAGGTILNALFGAALVNVQADSLTGLFSIAGFLLIYARVCTTLV 650
Cdd:TIGR04346 554 DGlaGQRAGQGYLLLLSILLRPPLMVIGFFAAILLSDVIGTLLNKLFAIALANVQSGSVTGILGFIAMLVIYAVILFLLI 633
                         650
                  ....*....|....*....
gi 535033303  651 AAVFALQAYLPDHVINFLG 669
Cdd:TIGR04346 634 AKLFGLIHELPDHVLRWIG 652
 
Name Accession Description Interval E-value
DotA_TraY TIGR04346
conjugal transfer/type IV secretion protein DotA/TraY; Members of this protein family include ...
38-669 2.31e-166

conjugal transfer/type IV secretion protein DotA/TraY; Members of this protein family include transfer protein TraY of IncI1 plasmid R64 and DotA (defect in organelle trafficking A) of Legionella pneumophila.


Pssm-ID: 275142  Cd Length: 652  Bit Score: 493.45  E-value: 2.31e-166
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535033303   38 LSRQALVTIFGDVVTNPLTAS--SNTIIGNLFMVFNAIIATMGIVWFLFIGIRHAVRTGHQGSVF-NNGRDVVGILSVVS 114
Cdd:TIGR04346   1 LSVQILDSLFGSVVNNPLGGSggPDTILGSIFGVFNLVILIVGSILLSYTIIAGLLNTAHDGELLgKKYSSVWTPLRTVI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535033303  115 GFLMIVPTASGWSLAQLVMLWGAsIMGIGSANIMVQTAAE--NIAEGYSMTVQPVHVSTRTAARGILEMELCKHAMNT-- 190
Cdd:TIGR04346  81 GIALLLPIAKGFSLIQLLVLWLA-VQGIGLANLVWSAGADalNFGGGVLVTTQPVQPKTAEVAKGLLESEVCRAADNVnk 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535033303  191 GLNDFNrTARSSTPPMSESSRTENGRYTV--TVSNGSAT-----CGSVSLSVKGNGsnKQSALAHFFNPFIETEYQGVLT 263
Cdd:TIGR04346 160 GSGAPN-LGPISKSSIGYSGAWSTGSTSYgyTLKFGNATgsvgiCGSVSFSFSGDD--AQSVNGAGLAPFTTGDLDSVCQ 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535033303  264 AQRSAMDTMLRDLDSAAQEFVSAYRTRRDTGNGNLPDIESRIQKAANRYEETVQKALPADNAETER---REQLKSYLTTY 340
Cdd:TIGR04346 237 AQQQALVTAISDLITAASEIANTIWQGASITGTALPEVAASIETAADAYEALVADALSAASSDQQAqikKENFATTAKEL 316
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535033303  341 GWVALGAWYQTFATANQRLEDLANRAPTVSGVSslgEAGDTEFLKEVKGAYQAQL----QNSPYTPALGTNTSSTEYRTA 416
Cdd:TIGR04346 317 GWASAGAWYWTISRLNQKVLAAANSLPTVTGPS---GSGLGSRFSGLFDAYIEALsqviLADAYATPAGTSALAGAEAVA 393
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535033303  417 EAAEPKSIIMKVWS--GENFADKIATSLSGTGT-SSDQLNPLIKMKNIGDYTMGITESIWAGYTTVRVLSTAGSNSVFGR 493
Cdd:TIGR04346 394 SAAEAGDNFSAIWKflRGLMSMWVGTSISFTSNeTSSGTNPLIAMKNIGDYLIGIAEATYGAGAVLGAVGSGVALGGVIA 473
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535033303  494 LV-NAVSGLSDAAKAFLEASAPPLYFLLFLLFCAGFSLSIYLPFIPFIFWMTGIGNWIVSVLIGCAAGPLWAATHLGTSQ 572
Cdd:TIGR04346 474 GFlGFVGGGAAALSGLLSAISFVLFPLALALFIMGLILAYYLPFIPFIIWMGAVVGWLILVVEAVVAAPLWALAHLLPEG 553
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535033303  573 DR--GSRAAYGYIYLIDSMIRPLLMVFGFFFASVAIVAGGTILNALFGAALVNVQADSLTGLFSIAGFLLIYARVCTTLV 650
Cdd:TIGR04346 554 DGlaGQRAGQGYLLLLSILLRPPLMVIGFFAAILLSDVIGTLLNKLFAIALANVQSGSVTGILGFIAMLVIYAVILFLLI 633
                         650
                  ....*....|....*....
gi 535033303  651 AAVFALQAYLPDHVINFLG 669
Cdd:TIGR04346 634 AKLFGLIHELPDHVLRWIG 652
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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