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Conserved domains on  [gi|535035206|gb|EQR82335|]
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insertion element IS1 1 protein insB [Escherichia coli HVH 137 (4-2124971)]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DDE_Tnp_IS1 super family cl44371
IS1 transposase; Transposase proteins are necessary for efficient DNA transposition. This ...
1-125 2.85e-79

IS1 transposase; Transposase proteins are necessary for efficient DNA transposition. This family represents bacterial IS1 transposases.


The actual alignment was detected with superfamily member pfam03400:

Pssm-ID: 281403  Cd Length: 131  Bit Score: 229.47  E-value: 2.85e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535035206    1 MDEQWGYVGAKSRQRWLFYAYDSLRKTVVAHVFGERTMATLGRLMSLLSPFDVVIWMTDGWPLYESRLKGKLHVISKRYT 80
Cdd:pfam03400   7 LDEQWGFVGAKARQHWLFYAYDRKRGGVLAHTFGERTDATCGELLALLSPFDIGILMSDDWGLYERELKGDKHLIGKIFT 86
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 535035206   81 QRIERHNLNLRQHLARLGRKLLSFSKSVELHDKVIGHYLNIKHYQ 125
Cdd:pfam03400  87 QRIERHNLNLRQHIARLARKSICFSKSVEIHDKVIGHFIEIHHFQ 131
 
Name Accession Description Interval E-value
DDE_Tnp_IS1 pfam03400
IS1 transposase; Transposase proteins are necessary for efficient DNA transposition. This ...
1-125 2.85e-79

IS1 transposase; Transposase proteins are necessary for efficient DNA transposition. This family represents bacterial IS1 transposases.


Pssm-ID: 281403  Cd Length: 131  Bit Score: 229.47  E-value: 2.85e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535035206    1 MDEQWGYVGAKSRQRWLFYAYDSLRKTVVAHVFGERTMATLGRLMSLLSPFDVVIWMTDGWPLYESRLKGKLHVISKRYT 80
Cdd:pfam03400   7 LDEQWGFVGAKARQHWLFYAYDRKRGGVLAHTFGERTDATCGELLALLSPFDIGILMSDDWGLYERELKGDKHLIGKIFT 86
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 535035206   81 QRIERHNLNLRQHLARLGRKLLSFSKSVELHDKVIGHYLNIKHYQ 125
Cdd:pfam03400  87 QRIERHNLNLRQHIARLARKSICFSKSVEIHDKVIGHFIEIHHFQ 131
InsB COG1662
Transposase and inactivated derivatives, IS1 family [Mobilome: prophages, transposons];
1-125 6.38e-54

Transposase and inactivated derivatives, IS1 family [Mobilome: prophages, transposons];


Pssm-ID: 441268 [Multi-domain]  Cd Length: 193  Bit Score: 167.18  E-value: 6.38e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535035206   1 MDEQWGYVGAKSRQRWLFYAYDSLRKTVVAHVFGERTMATLGRLMSLLSPFDVVIWMTDGWPLYESRLKGKLHVISKRYT 80
Cdd:COG1662   66 VDELWTFVGSKKNKVWIWYAVDRDTGRIVAFVVGDRDKKTARKLWEKLKPFEIAVIYTDGWKAYASLIPEKRHVVSKGYT 145
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 535035206  81 QRIERHNLNLRQHLARLGRKLLSFSKSVELHDKVIGHYLNIKHYQ 125
Cdd:COG1662  146 NHIERNNLTLRHRLKRLVRKTICFSKSLEMHDKAIKLFFHYYNFG 190
transpos_IS1 NF033558
IS1 family transposase; Proteins of this family are DDE transposases encoded by the IS1 family ...
1-100 2.42e-48

IS1 family transposase; Proteins of this family are DDE transposases encoded by the IS1 family elements usually through a translational frameshift mechanism.


Pssm-ID: 468085 [Multi-domain]  Cd Length: 199  Bit Score: 153.20  E-value: 2.42e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535035206   1 MDEQWGYVGAKSRQRWLFYAYDSLRKTVVAHVFGERTMATLGRLMSLLSPFDVVIWMTDGWPLYESRLKGKLHVISKRYT 80
Cdd:NF033558 100 LDELWTFVGNKKNKRWLWYAYDRKTKRILAYVFGDRSAETFRKLWALLKPFKIGFYCTDHWKVYAEFLPDEKHLVSKGET 179
                         90       100
                 ....*....|....*....|
gi 535035206  81 QRIERHNLNLRQHLARLGRK 100
Cdd:NF033558 180 QRIERENLTLRHRLARLVRK 199
 
Name Accession Description Interval E-value
DDE_Tnp_IS1 pfam03400
IS1 transposase; Transposase proteins are necessary for efficient DNA transposition. This ...
1-125 2.85e-79

IS1 transposase; Transposase proteins are necessary for efficient DNA transposition. This family represents bacterial IS1 transposases.


Pssm-ID: 281403  Cd Length: 131  Bit Score: 229.47  E-value: 2.85e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535035206    1 MDEQWGYVGAKSRQRWLFYAYDSLRKTVVAHVFGERTMATLGRLMSLLSPFDVVIWMTDGWPLYESRLKGKLHVISKRYT 80
Cdd:pfam03400   7 LDEQWGFVGAKARQHWLFYAYDRKRGGVLAHTFGERTDATCGELLALLSPFDIGILMSDDWGLYERELKGDKHLIGKIFT 86
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 535035206   81 QRIERHNLNLRQHLARLGRKLLSFSKSVELHDKVIGHYLNIKHYQ 125
Cdd:pfam03400  87 QRIERHNLNLRQHIARLARKSICFSKSVEIHDKVIGHFIEIHHFQ 131
InsB COG1662
Transposase and inactivated derivatives, IS1 family [Mobilome: prophages, transposons];
1-125 6.38e-54

Transposase and inactivated derivatives, IS1 family [Mobilome: prophages, transposons];


Pssm-ID: 441268 [Multi-domain]  Cd Length: 193  Bit Score: 167.18  E-value: 6.38e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535035206   1 MDEQWGYVGAKSRQRWLFYAYDSLRKTVVAHVFGERTMATLGRLMSLLSPFDVVIWMTDGWPLYESRLKGKLHVISKRYT 80
Cdd:COG1662   66 VDELWTFVGSKKNKVWIWYAVDRDTGRIVAFVVGDRDKKTARKLWEKLKPFEIAVIYTDGWKAYASLIPEKRHVVSKGYT 145
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 535035206  81 QRIERHNLNLRQHLARLGRKLLSFSKSVELHDKVIGHYLNIKHYQ 125
Cdd:COG1662  146 NHIERNNLTLRHRLKRLVRKTICFSKSLEMHDKAIKLFFHYYNFG 190
transpos_IS1 NF033558
IS1 family transposase; Proteins of this family are DDE transposases encoded by the IS1 family ...
1-100 2.42e-48

IS1 family transposase; Proteins of this family are DDE transposases encoded by the IS1 family elements usually through a translational frameshift mechanism.


Pssm-ID: 468085 [Multi-domain]  Cd Length: 199  Bit Score: 153.20  E-value: 2.42e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535035206   1 MDEQWGYVGAKSRQRWLFYAYDSLRKTVVAHVFGERTMATLGRLMSLLSPFDVVIWMTDGWPLYESRLKGKLHVISKRYT 80
Cdd:NF033558 100 LDELWTFVGNKKNKRWLWYAYDRKTKRILAYVFGDRSAETFRKLWALLKPFKIGFYCTDHWKVYAEFLPDEKHLVSKGET 179
                         90       100
                 ....*....|....*....|
gi 535035206  81 QRIERHNLNLRQHLARLGRK 100
Cdd:NF033558 180 QRIERENLTLRHRLARLVRK 199
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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