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Conserved domains on  [gi|535134085|gb|EQS79384|]
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4-hydroxybenzoate octaprenyltransferase [Escherichia coli HVH 164 (4-5953081)]

Protein Classification

4-hydroxybenzoate octaprenyltransferase( domain architecture ID 10797062)

4-hydroxybenzoate octaprenyltransferase catalyzes the conversion of 4-hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate in a Mg2+-sensitive manner

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ubiA_proteo TIGR01474
4-hydroxybenzoate polyprenyl transferase, proteobacterial; This model represents a family of ...
 10-288 3.68e-118

4-hydroxybenzoate polyprenyl transferase, proteobacterial; This model represents a family of integral membrane proteins that condenses para-hydroxybenzoate with any of several polyprenyldiphosphates. Heterologous expression studies suggest that for, many but not all members, the activity seen (e.g. octaprenyltransferase in E. coli) reflects available host isoprenyl pools rather than enzyme specificity. A fairly deep split by both clustering (UPGMA) and phylogenetics (NJ tree) separates this group (mostly Proteobacterial and mitochondrial), with several characterized members, from another group (mostly archaeal and Gram-positive bacterial) lacking characterized members. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


:

Pssm-ID: 130539  Cd Length: 281  Bit Score: 340.45  E-value: 3.68e-118
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085   10 LLAFHRLMRTDKPIGALLLLWPTLWALWVATP--GVPQLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTANRPLP 87
Cdd:TIGR01474   1 LLPYAKLMRADKPIGTLLLLWPCLWSLLLAAQagGIPPLYLLGLFTVGAILMRGAGCVINDIWDRDFDPQVERTKSRPLA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085   88 SGAVTEKEARALFVVLVLISFLLVLTLNTMTILLSIAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAAVSESVPL 167
Cdd:TIGR01474  81 SGAVSVRQAILFLLVQLLVALGVLLQLNPLTILLGVASLALVATYPFMKRITYWPQLVLGLAFGWGALMGWAAVTGDLST 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085  168 SCWLMFLANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKLIIGILQIGVLALMAIIGELNGLGWGYYWSILVAG 247
Cdd:TIGR01474 161 AAWVLYLANILWTLGYDTIYAMQDKEDDIKIGVKSTALRFGDNTKPWLGGLYALMILLLALAGLIAGLGPVYYLGLAAAA 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 535134085  248 ALFVYQQKLIANREREACFKAFMNNNYVGLVLFLGLAMSYW 288
Cdd:TIGR01474 241 LLLIRQIATLDIRDPENCLKLFKANNYVGLLLFAGIALGWL 281
 
Name Accession Description Interval E-value
ubiA_proteo TIGR01474
4-hydroxybenzoate polyprenyl transferase, proteobacterial; This model represents a family of ...
 10-288 3.68e-118

4-hydroxybenzoate polyprenyl transferase, proteobacterial; This model represents a family of integral membrane proteins that condenses para-hydroxybenzoate with any of several polyprenyldiphosphates. Heterologous expression studies suggest that for, many but not all members, the activity seen (e.g. octaprenyltransferase in E. coli) reflects available host isoprenyl pools rather than enzyme specificity. A fairly deep split by both clustering (UPGMA) and phylogenetics (NJ tree) separates this group (mostly Proteobacterial and mitochondrial), with several characterized members, from another group (mostly archaeal and Gram-positive bacterial) lacking characterized members. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 130539  Cd Length: 281  Bit Score: 340.45  E-value: 3.68e-118
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085   10 LLAFHRLMRTDKPIGALLLLWPTLWALWVATP--GVPQLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTANRPLP 87
Cdd:TIGR01474   1 LLPYAKLMRADKPIGTLLLLWPCLWSLLLAAQagGIPPLYLLGLFTVGAILMRGAGCVINDIWDRDFDPQVERTKSRPLA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085   88 SGAVTEKEARALFVVLVLISFLLVLTLNTMTILLSIAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAAVSESVPL 167
Cdd:TIGR01474  81 SGAVSVRQAILFLLVQLLVALGVLLQLNPLTILLGVASLALVATYPFMKRITYWPQLVLGLAFGWGALMGWAAVTGDLST 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085  168 SCWLMFLANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKLIIGILQIGVLALMAIIGELNGLGWGYYWSILVAG 247
Cdd:TIGR01474 161 AAWVLYLANILWTLGYDTIYAMQDKEDDIKIGVKSTALRFGDNTKPWLGGLYALMILLLALAGLIAGLGPVYYLGLAAAA 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 535134085  248 ALFVYQQKLIANREREACFKAFMNNNYVGLVLFLGLAMSYW 288
Cdd:TIGR01474 241 LLLIRQIATLDIRDPENCLKLFKANNYVGLLLFAGIALGWL 281
PT_UbiA_COQ2 cd13959
4-Hydroxybenzoate polyprenyltransferase; 4-Hydroxybenzoate polyprenyltransferase, also known ...
 17-286 3.00e-109

4-Hydroxybenzoate polyprenyltransferase; 4-Hydroxybenzoate polyprenyltransferase, also known as Coq2, catalyzes the prenylation of p-hydroxybenzoate with an all-trans polyprenyl group, an important step in ubiquinone (CoQ) biosynthesis. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260122 [Multi-domain]  Cd Length: 272  Bit Score: 317.49  E-value: 3.00e-109
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085  17 MRTDKPIGALLLLWPTLWALWVATPGVP--QLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTANRPLPSGAVTEK 94
Cdd:cd13959    1 MRLDKPIGTLLLLPPALWGLLLAAGGLPlpLLKLLLLFLLGAFLMRSAGCTINDIADRDIDAKVPRTKNRPLASGAISVK 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085  95 EARALFVVLVLISFLLVLTLNTMTILLSIAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAAVSESVPLSCWLMFL 174
Cdd:cd13959   81 EALLFLAVQLLLGLALLLQLNPLTILLSPIALLLVLIYPLMKRFTYWPQLVLGLAFGWGPLMGWAAVTGSLPLPALLLYL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085 175 ANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKLIIGILQIGVLALMAIIGELNGLGWGYYWSILVAGALFVYQQ 254
Cdd:cd13959  161 AVIFWTAGYDTIYAHQDREDDRKIGVKSTAVLFGDRTKLILALLLHLFVALLLLAGGLAGLGWPYYLGLGAAAHLLWQEH 240

                        250       260       270
                 ....*....|....*....|....*....|..
gi 535134085 255 KLIANREREACFKAFMNNNYVGLVLFLGLAMS 286
Cdd:cd13959  241 RLDLPDPLRSCLAFFLSNGWVGLLLFAGLLLD 272
UbiA COG0382
4-hydroxybenzoate polyprenyltransferase [Coenzyme transport and metabolism]; 4-hydroxybenzoate ...
 11-285 1.23e-89

4-hydroxybenzoate polyprenyltransferase [Coenzyme transport and metabolism]; 4-hydroxybenzoate polyprenyltransferase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440151  Cd Length: 280  Bit Score: 267.87  E-value: 1.23e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085  11 LAFHRLMRTDKPIGALLLLWPTLWALWVATPGVPQLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTANRPLPSGA 90
Cdd:COG0382    1 RAYLRLLRLDRPIGILLLLWPTLWALFLAAGGLPDLLLLLLAVLGTVLMRSAGYVINDYFDREIDRINERKPNRPLASGR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085  91 VTEKEARALFVVLVLISFLLVLTLNTMTILLSIAALALAWVYP-FMKRYTHLPQVVLGAAFGWSIPMAFAAVSESVPLSC 169
Cdd:COG0382   81 ISLREALLLAIVLLLLALALALLLNPLTFLLALAALALAWAYSlFLKRFTLLGNLVLGLLFGLGILMGFAAVTGSLPLSA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085 170 WLMFLANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKL-IIGILQIGVLALMAIIGELNGLGWGYYWSILVAG- 247
Cdd:COG0382  161 WLLALAAFLWTLAYDTIYDLEDREGDRKIGIKTLAILFGVRDALiIAGVLYALAVLLLLLLGLLAGLGLLYLLGLLAALl 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 535134085 248 ALFVYQQKLIANR--EREACFKAFMNNNYVGLVLFLGLAM 285
Cdd:COG0382  241 LLYLSQLWLLRPRkkDPARALKLFKLNMLLGLLLFLGIAL 280
PLN02809 PLN02809
4-hydroxybenzoate nonaprenyltransferase
 13-283 1.56e-59

4-hydroxybenzoate nonaprenyltransferase


Pssm-ID: 178405  Cd Length: 289  Bit Score: 191.44  E-value: 1.56e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085  13 FHRLMRTDKPIGALLLLWPTLWALWVATP--GVPQLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTANRPLPSGA 90
Cdd:PLN02809   9 YAKLARLDKPIGTWLLAWPCMWSIALAAPpgSLPDLKMLALFGCGALLLRGAGCTINDLLDRDIDKKVERTKLRPIASGA 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085  91 VTEKEARALFVVLVLISFLLVLTLNTMTILLSIAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAAVSESV-PLSC 169
Cdd:PLN02809  89 LTPFQGVGFLGAQLLLGLGILLQLNNYSRILGASSLLLVFTYPLMKRFTFWPQAFLGLTFNWGALLGWAAVKGSLdPAVV 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085 170 WLMFLANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKLIIGILQIGVLALMAIIGELNGLGWGYYWSILVAGAL 249
Cdd:PLN02809 169 LPLYASGVCWTLVYDTIYAHQDKEDDLKVGVKSTALRFGDDTKLWLTGFGAASIGGLALSGYNAGLGWPYYAGLAAAAGH 248

                        250       260       270
                 ....*....|....*....|....*....|....
gi 535134085 250 FVYQQKLIANREREACFKAFMNNNYVGLVLFLGL 283
Cdd:PLN02809 249 LAWQIQTVDLSSRADCNRKFVSNKWFGAIVFAGI 282
UbiA pfam01040
UbiA prenyltransferase family;
28-271 5.86e-56

UbiA prenyltransferase family;


Pssm-ID: 460038 [Multi-domain]  Cd Length: 250  Bit Score: 180.89  E-value: 5.86e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085   28 LLWPTLWALWVATPGVPQLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTANRPLPSGAVTEKEARALFVVLVLIS 107
Cdd:pfam01040   1 LLIPALAGLALAAGGVPDLLLLLLALLGTVLARAAANALNDYYDRDIDAIMPRTPNRPLPSGRISPREALIFALVLLALG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085  108 FLLVLTLNTMTILLSIAALALAWVYP-FMKRYTHLPQVVLGAAFGWSIPMAFAAVSESVPLSCWLMFLANILWAVAYDTQ 186
Cdd:pfam01040  81 LLLLLLLNPLTALLGLAALLLYVLYTlRLKRRTLLGQLVGGLAFGLPPLLGWAAVTGSLSPLALLLALALFLWTWAIALA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085  187 YAMVDRDDDVKIGIKSTAILFGQYDKLIIG-ILQIGVLALMAIIGELNGLGWGYYWSILVAGALFVYQQKLIANREREAC 265
Cdd:pfam01040 161 NDLRDREDDRKAGIKTLPVVLGRKAARILLaLLLAVALLLLLLLLLLLLGGLYLLLALLLAALALLYAARLLRLRDPKKD 240


                  ....*.
gi 535134085  266 FKAFMN 271
Cdd:pfam01040 241 AKAFFF 246
 
Name Accession Description Interval E-value
ubiA_proteo TIGR01474
4-hydroxybenzoate polyprenyl transferase, proteobacterial; This model represents a family of ...
 10-288 3.68e-118

4-hydroxybenzoate polyprenyl transferase, proteobacterial; This model represents a family of integral membrane proteins that condenses para-hydroxybenzoate with any of several polyprenyldiphosphates. Heterologous expression studies suggest that for, many but not all members, the activity seen (e.g. octaprenyltransferase in E. coli) reflects available host isoprenyl pools rather than enzyme specificity. A fairly deep split by both clustering (UPGMA) and phylogenetics (NJ tree) separates this group (mostly Proteobacterial and mitochondrial), with several characterized members, from another group (mostly archaeal and Gram-positive bacterial) lacking characterized members. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 130539  Cd Length: 281  Bit Score: 340.45  E-value: 3.68e-118
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085   10 LLAFHRLMRTDKPIGALLLLWPTLWALWVATP--GVPQLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTANRPLP 87
Cdd:TIGR01474   1 LLPYAKLMRADKPIGTLLLLWPCLWSLLLAAQagGIPPLYLLGLFTVGAILMRGAGCVINDIWDRDFDPQVERTKSRPLA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085   88 SGAVTEKEARALFVVLVLISFLLVLTLNTMTILLSIAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAAVSESVPL 167
Cdd:TIGR01474  81 SGAVSVRQAILFLLVQLLVALGVLLQLNPLTILLGVASLALVATYPFMKRITYWPQLVLGLAFGWGALMGWAAVTGDLST 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085  168 SCWLMFLANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKLIIGILQIGVLALMAIIGELNGLGWGYYWSILVAG 247
Cdd:TIGR01474 161 AAWVLYLANILWTLGYDTIYAMQDKEDDIKIGVKSTALRFGDNTKPWLGGLYALMILLLALAGLIAGLGPVYYLGLAAAA 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 535134085  248 ALFVYQQKLIANREREACFKAFMNNNYVGLVLFLGLAMSYW 288
Cdd:TIGR01474 241 LLLIRQIATLDIRDPENCLKLFKANNYVGLLLFAGIALGWL 281
PT_UbiA_COQ2 cd13959
4-Hydroxybenzoate polyprenyltransferase; 4-Hydroxybenzoate polyprenyltransferase, also known ...
 17-286 3.00e-109

4-Hydroxybenzoate polyprenyltransferase; 4-Hydroxybenzoate polyprenyltransferase, also known as Coq2, catalyzes the prenylation of p-hydroxybenzoate with an all-trans polyprenyl group, an important step in ubiquinone (CoQ) biosynthesis. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260122 [Multi-domain]  Cd Length: 272  Bit Score: 317.49  E-value: 3.00e-109
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085  17 MRTDKPIGALLLLWPTLWALWVATPGVP--QLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTANRPLPSGAVTEK 94
Cdd:cd13959    1 MRLDKPIGTLLLLPPALWGLLLAAGGLPlpLLKLLLLFLLGAFLMRSAGCTINDIADRDIDAKVPRTKNRPLASGAISVK 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085  95 EARALFVVLVLISFLLVLTLNTMTILLSIAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAAVSESVPLSCWLMFL 174
Cdd:cd13959   81 EALLFLAVQLLLGLALLLQLNPLTILLSPIALLLVLIYPLMKRFTYWPQLVLGLAFGWGPLMGWAAVTGSLPLPALLLYL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085 175 ANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKLIIGILQIGVLALMAIIGELNGLGWGYYWSILVAGALFVYQQ 254
Cdd:cd13959  161 AVIFWTAGYDTIYAHQDREDDRKIGVKSTAVLFGDRTKLILALLLHLFVALLLLAGGLAGLGWPYYLGLGAAAHLLWQEH 240

                        250       260       270
                 ....*....|....*....|....*....|..
gi 535134085 255 KLIANREREACFKAFMNNNYVGLVLFLGLAMS 286
Cdd:cd13959  241 RLDLPDPLRSCLAFFLSNGWVGLLLFAGLLLD 272
UbiA COG0382
4-hydroxybenzoate polyprenyltransferase [Coenzyme transport and metabolism]; 4-hydroxybenzoate ...
 11-285 1.23e-89

4-hydroxybenzoate polyprenyltransferase [Coenzyme transport and metabolism]; 4-hydroxybenzoate polyprenyltransferase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440151  Cd Length: 280  Bit Score: 267.87  E-value: 1.23e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085  11 LAFHRLMRTDKPIGALLLLWPTLWALWVATPGVPQLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTANRPLPSGA 90
Cdd:COG0382    1 RAYLRLLRLDRPIGILLLLWPTLWALFLAAGGLPDLLLLLLAVLGTVLMRSAGYVINDYFDREIDRINERKPNRPLASGR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085  91 VTEKEARALFVVLVLISFLLVLTLNTMTILLSIAALALAWVYP-FMKRYTHLPQVVLGAAFGWSIPMAFAAVSESVPLSC 169
Cdd:COG0382   81 ISLREALLLAIVLLLLALALALLLNPLTFLLALAALALAWAYSlFLKRFTLLGNLVLGLLFGLGILMGFAAVTGSLPLSA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085 170 WLMFLANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKL-IIGILQIGVLALMAIIGELNGLGWGYYWSILVAG- 247
Cdd:COG0382  161 WLLALAAFLWTLAYDTIYDLEDREGDRKIGIKTLAILFGVRDALiIAGVLYALAVLLLLLLGLLAGLGLLYLLGLLAALl 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 535134085 248 ALFVYQQKLIANR--EREACFKAFMNNNYVGLVLFLGLAM 285
Cdd:COG0382  241 LLYLSQLWLLRPRkkDPARALKLFKLNMLLGLLLFLGIAL 280
PLN02809 PLN02809
4-hydroxybenzoate nonaprenyltransferase
 13-283 1.56e-59

4-hydroxybenzoate nonaprenyltransferase


Pssm-ID: 178405  Cd Length: 289  Bit Score: 191.44  E-value: 1.56e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085  13 FHRLMRTDKPIGALLLLWPTLWALWVATP--GVPQLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTANRPLPSGA 90
Cdd:PLN02809   9 YAKLARLDKPIGTWLLAWPCMWSIALAAPpgSLPDLKMLALFGCGALLLRGAGCTINDLLDRDIDKKVERTKLRPIASGA 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085  91 VTEKEARALFVVLVLISFLLVLTLNTMTILLSIAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAAVSESV-PLSC 169
Cdd:PLN02809  89 LTPFQGVGFLGAQLLLGLGILLQLNNYSRILGASSLLLVFTYPLMKRFTFWPQAFLGLTFNWGALLGWAAVKGSLdPAVV 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085 170 WLMFLANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKLIIGILQIGVLALMAIIGELNGLGWGYYWSILVAGAL 249
Cdd:PLN02809 169 LPLYASGVCWTLVYDTIYAHQDKEDDLKVGVKSTALRFGDDTKLWLTGFGAASIGGLALSGYNAGLGWPYYAGLAAAAGH 248

                        250       260       270
                 ....*....|....*....|....*....|....
gi 535134085 250 FVYQQKLIANREREACFKAFMNNNYVGLVLFLGL 283
Cdd:PLN02809 249 LAWQIQTVDLSSRADCNRKFVSNKWFGAIVFAGI 282
UbiA pfam01040
UbiA prenyltransferase family;
28-271 5.86e-56

UbiA prenyltransferase family;


Pssm-ID: 460038 [Multi-domain]  Cd Length: 250  Bit Score: 180.89  E-value: 5.86e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085   28 LLWPTLWALWVATPGVPQLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTANRPLPSGAVTEKEARALFVVLVLIS 107
Cdd:pfam01040   1 LLIPALAGLALAAGGVPDLLLLLLALLGTVLARAAANALNDYYDRDIDAIMPRTPNRPLPSGRISPREALIFALVLLALG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085  108 FLLVLTLNTMTILLSIAALALAWVYP-FMKRYTHLPQVVLGAAFGWSIPMAFAAVSESVPLSCWLMFLANILWAVAYDTQ 186
Cdd:pfam01040  81 LLLLLLLNPLTALLGLAALLLYVLYTlRLKRRTLLGQLVGGLAFGLPPLLGWAAVTGSLSPLALLLALALFLWTWAIALA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085  187 YAMVDRDDDVKIGIKSTAILFGQYDKLIIG-ILQIGVLALMAIIGELNGLGWGYYWSILVAGALFVYQQKLIANREREAC 265
Cdd:pfam01040 161 NDLRDREDDRKAGIKTLPVVLGRKAARILLaLLLAVALLLLLLLLLLLLGGLYLLLALLLAALALLYAARLLRLRDPKKD 240


                  ....*.
gi 535134085  266 FKAFMN 271
Cdd:pfam01040 241 AKAFFF 246
ubiA PRK12873
4-hydroxybenzoate polyprenyltransferase;
7-286 1.05e-44

4-hydroxybenzoate polyprenyltransferase;


Pssm-ID: 171787 [Multi-domain]  Cd Length: 294  Bit Score: 153.28  E-value: 1.05e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085   7 QNKLLAFHRLMRTDKPIGALLLLWPTLWALWVATPGVPQLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTANRPL 86
Cdd:PRK12873   4 SIKLSPWFELLRWNKPTGRLILLIPAGWSLWLTPSAPPSLLLLLLIILGGLAVSGAGCIANDLWDRRIDRKVERTKNRPL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085  87 PSGAVTEKEARALFVVLVLISFLLVLTLNT----MTILLSIAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAA-- 160
Cdd:PRK12873  84 ARGKISLKTAYSLLIVLLLLSLFVVLSLPQpsrnLCLSLAFLALPPILIYPSAKRWFAYPQAILALCWGFAVLIPWAAae 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085 161 --VSESVPL-SCWlmfLANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKLIIGILQIGVLALMAIIGELNGLGW 237
Cdd:PRK12873 164 gsLNGGWPLlFCW---LATLLWTFGFDTVYAMADRRDDAKIGLNSSALSLGSNALKTVQICYFLTSIFLALAAFIAQVGF 240

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 535134085 238 gYYWsILVAGALFVYQQKLIANREREACFKA----FMNNNYVGLVLFLGLAMS 286
Cdd:PRK12873 241 -IFW-PFWLIASIGMQRDILKLFPEKQSIKTignhFSNQVILGSLLLLGLILA 291
ubiA PRK13106
prenyltransferase; Reviewed
 6-284 4.18e-30

prenyltransferase; Reviewed


Pssm-ID: 237283  Cd Length: 300  Bit Score: 115.21  E-value: 4.18e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085   6 TQNKLLAFHRLMRTDKPIGALLLLWptLWALwVATPGVPQLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTANRP 85
Cdd:PRK13106  11 TRSKFYIILRFLRIEQTFFSLPMAY--LGAF-VAIKGIPPISTLILIFLALFFLRTAGMTNDNLADLEIDAKNPRTKNRP 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085  86 LPSGAVTEKEARALFVVLVLISFLLVLTLNTMTILLSIAALALAWVYPFMKRYTHLPQVVLG-----AAFGWSIPMA--- 157
Cdd:PRK13106  88 LVTGAIKISEAKALITAGLILFFASAYLVNRWALLLSPIVALIAMSYPYMKRYTAFANYHLAsiqglAVFSGAVAVLgly 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085 158 ---FAAVSESVPlscWLMFLANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKLIIGILQIGVLALMAIIGELNG 234
Cdd:PRK13106 168 ansLIQVLLRVP---WLFVIGTILWAAGFDLYNHIPDAEFDREMGLHSFAVVLGKWALTFAGLNQLFSVVLDLLGDLYYG 244

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 535134085 235 LGWGYYWSILVAGALFVYQQKLIANREREAcfKAFMNNNYVGLVLFLGLA 284
Cdd:PRK13106 245 LGPIAIAATILHGLIMAYAYYLASKKGDFG--RAFYYNIYSSIVLGLGII 292
ubiA PRK12888
4-hydroxybenzoate octaprenyltransferase;
33-281 1.08e-20

4-hydroxybenzoate octaprenyltransferase;


Pssm-ID: 183814  Cd Length: 284  Bit Score: 89.39  E-value: 1.08e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085  33 LWALWVATPGVPQLWILAVFVAGVWLmRAAGCVVNDYADRKFDGHVKRTANRPLPSGAVTEKEARALFVVLVLISFLLVL 112
Cdd:PRK12888  26 LTAMFASDGSVHWADLLLVTVAMVGA-RTFAMAANRIIDREIDARNPRTAGRELVTGAVSVRTAWTGALVALAVFLGAAA 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085 113 TLNTMTILLSIAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAAVSESVPLSCWLMFLANILWAVAYDTQYAMVDR 192
Cdd:PRK12888 105 LLNPLCLALAPLAVAPLVVYPYAKRFTNFPHAILGLAQAVGPVGAWIAVTGTWSWPAVLLGLAVGLWIGGFDLIYACQDA 184

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085 193 DDDVKIGIKSTAILFGQYDKLIIG-ILQIGVLALMAIIGELNGLGWGYYWSILVAGALFVYQQKLIANREREACFKAF-M 270
Cdd:PRK12888 185 EVDRRIGVRSVPARFGVRAALWASrVAHVVTFALFVWFGLAVGFGALWWIGLAITAGAFAYEHAIVSPTDLSRVNRAFfT 264

                        250
                 ....*....|.
gi 535134085 271 NNNYVGLVLFL 281
Cdd:PRK12888 265 ANGFVGIALFG 275
PT_UbiA_Cox10 cd13957
Protoheme IX farnesyltransferase; Protoheme IX farnesyltransferase (also called heme O ...
 21-281 8.18e-20

Protoheme IX farnesyltransferase; Protoheme IX farnesyltransferase (also called heme O synthase, heme A:farnesyltransferase, cytochrome c oxidase subunit X [Cox10]) converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of the heme B porphyrin ring with a hydroxyethyl farnesyl side group. It is localized at the mitochondrial inner membrane. Eukaryotic Cox10 is important for the maturation of the heme A prosthetic group of cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, that catalyzes the electron transfer from reduced cytochrome c to oxygen. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260120  Cd Length: 271  Bit Score: 86.72  E-value: 8.18e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085  21 KPIGALLLLWPTLWALWVATPGVPQLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTANRPLPSGAVTEKEARALF 100
Cdd:cd13957    5 KPRITLLVLLTALAGYLLAPGGVPDLLLLLLTLLGTALVSASANALNQYIERDIDAKMKRTRNRPLPSGRISPKHALIFG 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085 101 VVLVLISF-LLVLTLNTMTILLSIAALAL-AWVYPFMKRYTHLPQVVLGAAFGwSIP--MAFAAVSESVPLSCWLMFLAN 176
Cdd:cd13957   85 LVLGILGLaLLALFVNPLTALLGLLGIFLyVFVYTPLKKRTTPLNTVIGGIAG-AIPplIGWAAATGSLDLGAWLLFLIL 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085 177 ILWavaydtQY------AMVDRDDDVKIGIKSTAILFG-QYDKLIIGILQIGVLALMAIIGELNGLGWGYYWSILVAGAL 249
Cdd:cd13957  164 FLW------QPphfwalAILYRDDYARAGIPMLPVVKGeRRTKRQILLYTLLLVPLSLLLYLLGLTGWIYLVVALLLGLY 237

                        250       260       270
                 ....*....|....*....|....*....|....
gi 535134085 250 FVYQ-QKLIANREREACFKAFMN-NNYVGLVLFL 281
Cdd:cd13957  238 FLYLaIKLYRSPDDKWARKLFFAsLIYLPLLFLL 271
ubiA PRK12886
prenyltransferase; Reviewed
 40-288 3.14e-19

prenyltransferase; Reviewed


Pssm-ID: 237247  Cd Length: 291  Bit Score: 85.51  E-value: 3.14e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085  40 TPGVPQL-WILAVFVAGvwlmRAAGCVVNDYADRKFDGHVKRTANRPLPSGAVTeKEARALFVVLVLISFLLV-LTLNTM 117
Cdd:PRK12886  38 LPGASQLdWILMAMVGA----RTAAMGFNRLIDAEIDARNPRTAGRAIPAGLIS-KGSAILFIVLSSLLMLFAaWFLNPL 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085 118 TILLSIAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAAVSESVPLSCWLMFLANILWAVAYDTQYAMVDRDDDVK 197
Cdd:PRK12886 113 CLYLSPPALFFLLLYSYCKRFTALAHVVLGFCLALAPLGAWIAIRGTIELPAILLGLAVLFWVAGFDILYALQDLEFDRK 192

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085 198 IGIKSTAILFGQYDKLIIG-ILQIGVLALMAIIGELNGLGWGYYWSILVAGALFVYQQKLIANREREACFKAFMN-NNYV 275
Cdd:PRK12886 193 EGLHSIPAKLGVNGSLWIArVFHLLMIGFLFALGISAGLGPWFLAGLAVTGILLLYEHWLLRGGDLTRLDAAFFNmNGYI 272

                        250
                 ....*....|...
gi 535134085 276 GLVLFLGLAMSYW 288
Cdd:PRK12886 273 SVTLFAATLFDRL 285
PRK04375 PRK04375
protoheme IX farnesyltransferase; Provisional
 27-288 6.65e-19

protoheme IX farnesyltransferase; Provisional


Pssm-ID: 235293  Cd Length: 296  Bit Score: 84.42  E-value: 6.65e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085  27 LLLWPTLWALWVATPGVPQLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTANRPLPSGAVTEKEARALFVVLVLI 106
Cdd:PRK04375  24 LNLFTALGGMLLAPPGVPPLLLLLLTLLGIALVAGAAGALNNYIDRDIDAKMERTKNRPLVTGRISPREALIFGLVLGVL 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085 107 SF-LLVLTLNTMTILLSIAALAL-AWVYP-FMKRYThlPQ-VVLGAAFGWSIPM-AFAAVSESVPLSCWLMFLANILWAV 181
Cdd:PRK04375 104 GFlLLGLFVNPLAAWLTLAGIFFyVVVYTlWLKRRT--PQnIVIGGAAGAMPPLiGWAAVTGSLSWEALILFLIIFLWTP 181

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085 182 AYDTQYAMVDRDD--DVKI-------GIKSTAILFgqydkLIIGILQIGVLALMAIIGElngLGWGYYWSILVAGALFVY 252
Cdd:PRK04375 182 PHFWALAIFRKDDyaAAGIpmlpvvkGIRVTKRQI-----LLYTVLLVAVSLLPVLLGM---AGLLYLVVALLLGAWFLY 253

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 535134085 253 Q-QKLIANREREACFKAFMNNNYVGLVLFLGLAMSYW 288
Cdd:PRK04375 254 YaWRLYRKDDRKWARKLFRYSINYLTLLFVALLVDHL 290
PT_UbiA cd13956
UbiA family of prenyltransferases (PTases); Many characterized members of the UbiA ...
 15-284 1.56e-17

UbiA family of prenyltransferases (PTases); Many characterized members of the UbiA prenyltransferase family are aromatic prenyltransferases and play an important role in the biosynthesis of heme, chlorophyll, vitamin E, and vitamin K. They contain two copies of a motif similar to the active site DxxD motif of trans-prenyltransferases and are potentially related. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260119 [Multi-domain]  Cd Length: 271  Bit Score: 80.47  E-value: 1.56e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085  15 RLMRTdkPIGALLLLWPTLWALWVATPGVPQLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRtaNRPLPSGAVTEK 94
Cdd:cd13956    2 RLMRP--YTLLYVLAPALAGAALAGAFAGPLPALLLLALLAVFLGAGAGYALNDYTDRELDAINKP--DRPLPSGRLSPR 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085  95 EARALFVVLVLISFLLVLTLNTMTILLSIAALALAWVYPFMKRYTHLPQ-VVLGAAFGWSIPMAFAAVSE-SVPLSCWLM 172
Cdd:cd13956   78 QALAFAAALLLVGLALALALGPLALLLLLAGLLLGLAYSLGLKRLKLGGwGVLGYATGLALLPGLGAVAAgGLVPLALLL 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085 173 FLANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGQ--YDKLIIGILQIGVLALMAIIGELNGLGWGYYWSILVAGALF 250
Cdd:cd13956  158 ALVFLLLGLGINLYNDLPDVEGDRAAGIRTLPVRLGPrrARRLAAGLLLAALILVVLLAVAGLLGPLALLALLAVALLAL 237

                        250       260       270
                 ....*....|....*....|....*....|....
gi 535134085 251 VYQQKLIANREREAcfKAFMNNNYVGLVLFLGLA 284
Cdd:cd13956  238 RARFARADRLPALP--RGFLLLAVYRLLLFAALL 269
cyoE_ctaB TIGR01473
protoheme IX farnesyltransferase; This model describes protoheme IX farnesyltransferase, also ...
 27-283 8.25e-15

protoheme IX farnesyltransferase; This model describes protoheme IX farnesyltransferase, also called heme O synthase, an enzyme that creates an intermediate in the biosynthesis of heme A. Prior to the description of its enzymatic function, this protein was often called a cytochrome o ubiquinol oxidase assembly factor. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin]


Pssm-ID: 273645  Cd Length: 280  Bit Score: 72.66  E-value: 8.25e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085   27 LLLWPTLWALWVAT-PGVPQLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTANRPLPSGAVTEKEARALFVVLVL 105
Cdd:TIGR01473  14 LLLITAFAGMWLAPgGALVNPPLLLLTLLGTTLAAASANAFNMYIDRDIDKKMKRTRNRPLVTGRISPREALAFGLLLGV 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085  106 ISF-LLVLTLNTMTILLSIAALAL-AWVY-PFMKRYTHLpQVVLGAAFGwSIP--MAFAAVSESVPLSCWLMFLANILWA 180
Cdd:TIGR01473  94 LGVaILAAFVNPLAALLGLFGIFFyVIVYtIWLKRRTPQ-NTVIGGFAG-AVPplIGWAAVTGSISLGAWLLFAIIFLWQ 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085  181 VAYDTQYAMVDRDDDVKIGIKSTAILFG-QYDKLIIGILQIGVLALMAIIGELNGLGWGYYWSILVAGALFVYQ--QKLI 257
Cdd:TIGR01473 172 PPHFWALALKYKDDYRAAGIPMLPVVKGeRITKRQIALYTAALLPVSLLLAFLGGTGWLYLIVATLLGALFLYLafKFYR 251

                         250       260
                  ....*....|....*....|....*..
gi 535134085  258 ANREREACFKAFM-NNNYVGLVLFLGL 283
Cdd:TIGR01473 252 DPTDRKKARKLFKfSLIYLALLFVALL 278
ubiA PRK12874
4-hydroxybenzoate polyprenyltransferase;
66-288 6.85e-12

4-hydroxybenzoate polyprenyltransferase;


Pssm-ID: 237242  Cd Length: 291  Bit Score: 64.64  E-value: 6.85e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085  66 VNDYADRKFDGHVKRTANRPLPSGAVTEKeARALFVVLVLISFLLVLTL-NTMTILLSIAALALAWVYPFMKRYTHLPQV 144
Cdd:PRK12874  66 FNRLVDRDIDKDNPRTANRPSVDGRISVK-SMVLFIVLNALIFIGVSYFiNPLAFKLSFPFLIVLGGYSYFKRFSSLAHL 144

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085 145 VLGAAFGWSiPMAFA-AVSESVPLSCWLMFLANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKLIIGIL--QIG 221
Cdd:PRK12874 145 VLGLSLGLA-PIAGVvAVLGEIPLWSVFLALGVMFWVAGFDLLYSLQDMEFDKKRGLHSIPSKFGEKATLFISRLfhLLA 223

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 535134085 222 VLALMAIIGELNGLGWGYYwSILVAGALFVYQQKLIaNREREACFKAFMN-NNYVGLVLFLGLAMSYW 288
Cdd:PRK12874 224 VLFWLLFVWCAHLGLFAYL-GVIVSALILLYEHYLV-RKDFKKIDKAFFTlNGYLGIVFFIFIVLDVL 289
ubiA PRK12895
prenyltransferase; Reviewed
 48-286 7.04e-12

prenyltransferase; Reviewed


Pssm-ID: 237251  Cd Length: 286  Bit Score: 64.45  E-value: 7.04e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085  48 ILAVFVAGVwLMRAAGCVVNDYADRKFDGHVKRTANRPLPSGAVTEKEARALFVVLVLISFLLVLTLNTMTILLSIAALA 127
Cdd:PRK12895  39 ILLILIAAV-SARTSAMSINRIEGLRYDMINPRKKDWALVSGRIKMREAIAFTIIFIAIFEICTFLLNRLVFILSPIVIF 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085 128 LAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAAVSESVP--LSCWLMFLANILWAVAYDTQYAMVDRDDDVKIGIKSTAI 205
Cdd:PRK12895 118 LFIIDPFLKRYTAWRHIYMGSIIGLGVLAGYLAVIPAFPynLLIYIIFISSSLWIAGFDIIYVIPDIEYDKINGLKTIMN 197

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085 206 LFGQYDKLIIGIL-QIGVLALMAIIGELNGLGWgYYWSILVAGALFVYQQKLIANREREACFKAFMN-NNYVGLVLFLGL 283
Cdd:PRK12895 198 TYGIKNGLYISDIfHISSLILFWISGIYIRTLW-YLAALIIIYTLVIYQHLIIDPRNPINKRMSFFNaNSFIGFVFLIGI 276


                 ...
gi 535134085 284 AMS 286
Cdd:PRK12895 277 ILS 279
ubiA PRK12876
prenyltransferase; Reviewed
 60-280 1.96e-11

prenyltransferase; Reviewed


Pssm-ID: 237244  Cd Length: 300  Bit Score: 63.23  E-value: 1.96e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085  60 RAAGCVVNDYADRKFDGHVKRTANRPLPSGAVTEKEAralFVVLVLISFLLVLT---LNTMTILLSIAALALAWVYPFMK 136
Cdd:PRK12876  60 RTVGIIVNQIIDCAIDKKNPRTSSRVLPAKLLSINFS---MLLLTLCSFLFLSLcwlLNPLCFSLAVLSTLLMIIYPYTK 136

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085 137 RYTHLPQVVLGAAFGWSIPMAFAAVSESvPLSCWLMFLANiLWAV-------AYDTQYAMVDRDDDVKIGIKSTAILFGQ 209
Cdd:PRK12876 137 RVTFLCHWILGLVYYLAILMNFFAIIET-PLSFSLFCMAS-LWGIsfgmiiaANDIIYAIQDLEFDRKEGLFSIPARFGE 214

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 535134085 210 YDKLII--GILQIGVLALMAIIGELNGLGWGYYWSIL-VAGALFV---YQQKLIANREREACFkaFMNNNYVGLVLF 280
Cdd:PRK12876 215 KKAIRIasANLIASAIAYLLIGYFVSNKKIFYLCSLVpLTVILKTikhYSLIDKKKSTLEQKF--FLGNIYLALSFF 289
ubiA PRK12884
prenyltransferase; Reviewed
 9-268 4.43e-11

prenyltransferase; Reviewed


Pssm-ID: 183812  Cd Length: 279  Bit Score: 61.90  E-value: 4.43e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085   9 KLLAFHRLMRTDKPIGALLLLwptLWALWVATPGVPQLWILAVFVAGVWLMrAAGCVVNDYADRKFDgHVKRTaNRPLPS 88
Cdd:PRK12884   3 KMKAYLELLRPEHGLMAGIAV---VLGAIIALGGLPLDEALLGFLTAFFAS-GSANALNDYFDYEVD-RINRP-DRPIPS 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085  89 GAVTEKEARALFVVLVLISFLLVLTLNTMTILLSIAALALAWVYPFM-KRYTHLPQVVLgaAFGWSIPMAFAA-VSESVP 166
Cdd:PRK12884  77 GRISRREALLLAILLFILGLIAAYLISPLAFLVVILVSVLGILYNWKlKEYGLIGNLYV--AFLTGMTFIFGGiAVGELN 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085 167 LSCWLMFLANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKLIIGILQIGVLALMAIIGELNG-LGWGYYWSILV 245
Cdd:PRK12884 155 EAVILLAAMAFLMTLGREIMKDIEDVEGDRLRGARTLAILYGEKIAGRIAAALFILAVLLSPLPYLFGiFNILYLAPVLV 234

                        250       260
                 ....*....|....*....|....
gi 535134085 246 AGALFVYQ-QKLIANREREACFKA 268
Cdd:PRK12884 235 ADLIFLYSaYSLLRSQDRETIRKV 258
PT_UbiA_DGGGPS cd13961
Geranylgeranylglycerol-phosphate geranylgeranyltransferase; Digeranylgeranylglyceryl phosphate ...
 46-264 1.78e-10

Geranylgeranylglycerol-phosphate geranylgeranyltransferase; Digeranylgeranylglyceryl phosphate synthase (DGGGPS) transfers a geranylgeranyl group from geranylgeranyl diphosphate to (S)-3-O-geranylgeranylglyceryl phosphate to form (S)-2,3-di-O-geranylgeranylglyceryl phosphate, as part of the isoprenoid ether lipid biosynthesis. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260124  Cd Length: 270  Bit Score: 60.21  E-value: 1.78e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085  46 LWILAVFVAGVWLMRAAGCVVNDYADRKFDgHVKRTaNRPLPSGAVTEKEARALFVVLVLISFLLVLTLNTMTILLSIAA 125
Cdd:cd13961   34 DLELLLLFLSVFLIAAAGYIINDYFDVEID-RINKP-DRPIPSGRISRREALILSILLNALGLILAFLLSPLALLIALLN 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085 126 LALAWVYP-FMKRYTHLPQVVLGAAFGWSIPMAFAAVSESVPLScWLMFLANILWAVAYDTQYAMVDRDDDVKIGIKSTA 204
Cdd:cd13961  112 SLLLWLYShKLKRTPLIGNLLVALLTGLPFLFGGLAAGNLLLII-LLLALFAFLITLGREIVKDIEDVEGDRAEGARTLP 190

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 535134085 205 ILFG-QYDKLIIGILQIGVLALMAIIGELNGLGWGYYWSILVAGALFVYQQKLIANREREA 264
Cdd:cd13961  191 IVYGiKKAKKIAALLLLLAILLSPLPYLLGGLGILYLILIIIADLLFLYSAIRLAKSPKDY 251
PRK09573 PRK09573
(S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase; Reviewed
 48-281 2.30e-07

(S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase; Reviewed


Pssm-ID: 181963  Cd Length: 279  Bit Score: 51.11  E-value: 2.30e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085  48 ILAVFVagVWLMRAAGCVVNDYADRKFDGHVKrtANRPLPSGAVTEKEARALFVVLVLISFLLVLTLNTMTILLSIAALA 127
Cdd:PRK09573  40 ILAALV--VFLVCAGGNVINDIYDIEIDKINK--PERPIPSGRISLKEAKIFSITLFIVGLILSIFINIYAFLIALLNSI 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085 128 LAWVYP-FMKRYTHLPQVVLGAAFGWSIpmAFAAVSESVPLSCWLMFLANILWAVAYDTQYAMVDRDDDVKIGIKSTAIL 206
Cdd:PRK09573 116 LLYLYAkDLKKTGLIGNLIVAYLTGLSF--IFGGLAVFNVLRIIILFLCAFFSTWSREIVKDIEDIEGDLKENVITLPIK 193

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085 207 FGQYDKLIIGILQIGVLALMAIIGELNG-LGWGYYWSILVAGALFVYQQ-KLIANREREACFKAFMNNNY---VGLVLFL 281
Cdd:PRK09573 194 YGIKKSWYIAKILLILAIVLSPLPYFLGiFGIYYLIVVIICDILFIIAMlILLKNPSIEGASKASKYLKIimiLGLIAFL 273
PT_UbiA_UBIAD1 cd13962
1,4-Dihydroxy-2-naphthoate octaprenyltransferase; Human UBIAD1 is an enzyme involved in the ...
 42-286 1.12e-06

1,4-Dihydroxy-2-naphthoate octaprenyltransferase; Human UBIAD1 is an enzyme involved in the synthesis of MK-4. Menaquinones (MKs, also called bacterial forms) are one of the two forms of natural vitamin K, the other being the plant form, phylloquinone (PK). All forms of vitamin K have a 2-methyl-1,4-naphthoquinone (menadione; K3) ring structure in common. At the 3-position of the ring, PK has a phytyl side chain while MKs have several repeating prenyl units. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260125  Cd Length: 283  Bit Score: 49.05  E-value: 1.12e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085  42 GVPQLWILAVFVAGVWLMRAAGCVVNDYAD--RKFDGHVKRTANRPLPSGAVTEKEARALFVVLVLISFLLVLTLNTMTI 119
Cdd:cd13962   28 GFFNWLLFLLALLAALLLQIGVNLANDYFDykKGTDTEPRSGPSRVLVSGLLSPRQVLRAALVLLLLAALLGLYLVALGG 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085 120 LLSIAA----LALAWVY---PFMKRYTHLPQVVLGAAFGWSIPM-AFAAVSESVPLSCWLMFLANILWAVAydTQYA--M 189
Cdd:cd13962  108 WLLLLLgllgILAGYFYtggPFPLSYRGLGELFVFLFFGLLAVLgTYYVQTGSLSWEVLLAALPLGLLIAA--ILLAnnI 185

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085 190 VDRDDDVKIGIKSTAILFG-QYDKLIIGILQIGVLALMAIIGELNGLGWGYYWSILVagALFVYQQKLIANREREACFKA 268
Cdd:cd13962  186 RDIEADRAAGKRTLAVRLGrKRARRLYAALLLLAYLLLLLLVLLGLLPLWSLLALLS--LPLAIKLLRRLLRKADKPLLL 263

                        250
                 ....*....|....*...
gi 535134085 269 FMNNNYVGLVLFLGLAMS 286
Cdd:cd13962  264 IALKLTALLTLLFGLLLA 281
ubiA PRK12882
prenyltransferase; Reviewed
 38-110 1.16e-06

prenyltransferase; Reviewed


Pssm-ID: 183811  Cd Length: 276  Bit Score: 48.82  E-value: 1.16e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 535134085  38 VATPGVPQLWILAVfvagVWLMRAAGCVVNDYADRKFDgHVKRtANRPLPSGAVTEKEARA----LFVVLVLISFLL 110
Cdd:PRK12882  33 ILSSPSLTGLAFAA----VFLATGAGNAINDYFDREID-RINR-PDRPIPSGAVSPRGALAfsilLFAAGVALAFLL 103
ubiA PRK12883
prenyltransferase UbiA-like protein; Reviewed
 38-268 6.06e-06

prenyltransferase UbiA-like protein; Reviewed


Pssm-ID: 171796  Cd Length: 277  Bit Score: 46.65  E-value: 6.06e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085  38 VATPGVPQLWILAVFVAGVWLMRAAGCVVNDYADRKFDgHVKRtANRPLPSGAVTEKEARALFVVLVLISFLLVLTLNTM 117
Cdd:PRK12883  28 VALGGIPPIKTLILIFLVVYLGCSGGNTINDYFDYEID-KINR-PNRPLPRGAMSRKAALYYSLLLFAVGLALAYLINIE 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085 118 TILLSIAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAAVSESVPLSCWL---MFLANILWAVAYDTQyamvDRDD 194
Cdd:PRK12883 106 AFLFALGAYVLMFLYAWKLKPLPFIGNVVVALLTGATPIYGAIAVGRIGLAGYLaicAFLVNVAREIMKDIE----DIEG 181

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 535134085 195 DVKIGIKSTAILFGQYDKLIIGILqIGVLALMAIIGELN-GLGWGYYWSILVAGALFVYQQKLIANREREACFKA 268
Cdd:PRK12883 182 DKAKGAKTLPIIIGKKRAAYIGAI-FGVLTVIASFLPVKaGIGLGYLPIIIVDAIILYAAYLVLRNPDRETAHKG 255
PT_UbiA_2 cd13963
UbiA family of prenyltransferases (PTases), Unknown subgroup; Many characterized members of ...
 65-116 7.28e-05

UbiA family of prenyltransferases (PTases), Unknown subgroup; Many characterized members of the UbiA prenyltransferase family are aromatic prenyltransferases and play an important role in the biosynthesis of heme, chlorophyll, vitamin E, and vitamin K. They contain two copies of a motif similar to the active site DxxD motif of trans-prenyltransferases and are potentially related. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways. The function of this subgroup is unknown.


Pssm-ID: 260126  Cd Length: 278  Bit Score: 43.23  E-value: 7.28e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 535134085  65 VVNDYADRKFDGH--VKRtaNRPLPSGAVTEKEARALFVVLVLISFLLVLTLNT 116
Cdd:cd13963   51 ILNDLLDLEADRLhpTKR--NRPIASGRLSIPAALALAVVLLLAGLALALLLSP 102
PT_UbiA_1 cd13964
UbiA family of prenyltransferases (PTases), Unknown subgroup; Many characterized members of ...
 35-175 8.16e-05

UbiA family of prenyltransferases (PTases), Unknown subgroup; Many characterized members of the UbiA prenyltransferase family are aromatic prenyltransferases and play an important role in the biosynthesis of heme, chlorophyll, vitamin E, and vitamin K. They contain two copies of a motif similar to the active site DxxD motif of trans-prenyltransferases and are potentially related. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways. The function of this subgroup is unknown.


Pssm-ID: 260127  Cd Length: 282  Bit Score: 43.34  E-value: 8.16e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085  35 ALWVATPGVPQLWILAVFVAGVwLMRAAGCVVNDYADRKFDGhVKRtANRPLPSGAVTEKEARALFVVLVLISFLLVLTL 114
Cdd:cd13964   21 AALAGGGLGPVLRLALLLLASV-LLYAAGMVLNDVFDAELDA-RER-PERPIPSGRVSRGAALALGAGLLAAGVALAALV 97

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 535134085 115 NTMTILLSIAALALAWVYP-FMKRYTHLPqVVLGAAFGWSIPMAFAAVSESVPLSCWLMFLA 175
Cdd:cd13964   98 GRLSGLVALLLAAAILLYDaWLKHTPLGP-LLMGLCRGLNLLLGASAAAAGGLGPALLAALA 158
PT_UbiA_chlorophyll cd13958
Bacteriochlorophyll/chlorophyll synthetase; Chlorophyll synthase catalyzes the last step of ...
 44-253 1.06e-04

Bacteriochlorophyll/chlorophyll synthetase; Chlorophyll synthase catalyzes the last step of chlorophyll (Chl) biosynthesis, the addition of the tetraprenyl (phytyl or geranylgeranyl) side chain. In plant chloroplast, the chlorophyll synthase is located in thylakoid membrane and has been shown to also have a regulatory or channeling function. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260121  Cd Length: 277  Bit Score: 42.99  E-value: 1.06e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085  44 PQLWILAVFVAGVWLMRAAGC----VVNDYADRKFDGhvKRTANRPLPSGAVTEKEARALFVVLVLISFLLVLTLNTMTI 119
Cdd:cd13958   29 WSNWDVWLLLLGMLLAGPLLTgtsqTINDYYDREVDA--INEPYRPIPSGRISEREALWNIWVLLLLSLLVALFLDGPWV 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085 120 LLSIAA-LALAWVY---PF-MKR------------YTHLPQVVLGAAFGWSIPmafaavSESVPLSCW-------LMFLa 175
Cdd:cd13958  107 FAAAVVgLVLAYIYsapPLkLKQngwwgnaavglsYEGLPWWAGAAAFAGLLT------WESLALALLysigahgIMTL- 179

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 535134085 176 NILWAVAYDTQYAMvdRDDDVKIGIKSTAILFGqydkLIIGILQIGVLALMAIigelnglgWGYYWSILVAGALFVYQ 253
Cdd:cd13958  180 NDFKSIEGDRQLGL--RSLPVALGVDTAAWIAC----GVIDVPQLAVAALLLA--------WGETWYAAVVGALLLAQ 243
PRK12324 PRK12324
decaprenyl-phosphate phosphoribosyltransferase;
8-115 1.62e-04

decaprenyl-phosphate phosphoribosyltransferase;


Pssm-ID: 237058  Cd Length: 295  Bit Score: 42.54  E-value: 1.62e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085   8 NKLLAFHRLMRTDKPIGALLLLWPTLWALWVATPGVPQLWILAvFVAgVWLMRAAGCVVNDYADRKFDG-H-VKRtaNRP 85
Cdd:PRK12324   9 NLLAGYLKLLRPKQWIKNLFVFAAPIFAGNLLNPGALLKVLLA-FVL-FCLASSAVYLVNDIRDVEADRlHpTKR--NRP 84

                         90       100       110
                 ....*....|....*....|....*....|
gi 535134085  86 LPSGAVTEKEARALFVVLVLISFLLVLTLN 115
Cdd:PRK12324  85 IASGVVSVSLAYILAVVLLVASLALAYLLS 114
PRK07566 PRK07566
chlorophyll synthase ChlG;
4-275 2.56e-04

chlorophyll synthase ChlG;


Pssm-ID: 236052  Cd Length: 314  Bit Score: 41.83  E-value: 2.56e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085   4 SLTQNKLLAFHRLMrtdKPIgalllLW-PTLWALW--VATPGVPQLWILAV--FVAGVWL----MRAAGCVVNDYADRKF 74
Cdd:PRK07566  21 SPTTSIWKARLQLM---KPI-----TWfPPMWAFLcgAVSSGAFGWTLENVlkLLAGMLLagplLCGTSQTLNDYFDREV 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085  75 DghvkrtA----NRPLPSGAVTEKEARALFVVLVLISFLLVLTLNTMTILLSIAALALAWVY---PF-MKRYTHLPQVVL 146
Cdd:PRK07566  93 D------AinepYRPIPSGAISLRWVLYLIAVLTVLGLAVAYLLGPWVFLAALLGLFLAWIYsapPLrLKQNGWLGNYAV 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085 147 GA---AFGWsipMAFAAVSESVPLSCWLMFLANILWAVAYDTqyaMVDRD-----DDVKIGIKSTAILFGQYDK-----L 213
Cdd:PRK07566 167 GLsyeGLPW---WAGAAAFGAGLPSWPIVILALLYSLGAHGI---MTLNDfksveGDRQLGLRSLPVVFGEKNAariacV 240

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 535134085 214 IIGILQIGVLALMaiigelngLGWGYYWSILVAGAL----FVYQQKLIAN-REREACFKAFMNNNYV 275
Cdd:PRK07566 241 VIDLFQLAVIALL--------LAWGQPLYAAIVGLLlipqITLQDRLLRDpLERDVWYNASAQPFYV 299
ubiA PRK12871
prenyltransferase; Reviewed
 62-114 6.48e-04

prenyltransferase; Reviewed


Pssm-ID: 106000  Cd Length: 297  Bit Score: 40.57  E-value: 6.48e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 535134085  62 AGCVVNDYADRKFD-----GHVKRT----ANRPLPSGAVTEKEARALFVVLVLISFLLVLTL 114
Cdd:PRK12871  56 AGFVLNDYVDRKRDrldveNTLTRYwrpfKERPIPSGKLSSKNAFALFILLAAVTSALILTL 117
PLN02776 PLN02776
prenyltransferase
 38-201 1.80e-03

prenyltransferase


Pssm-ID: 215415  Cd Length: 341  Bit Score: 39.34  E-value: 1.80e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085  38 VATPGVPQLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTANRPLPSGAVTEKEArALFVVLVLISFLLVLTL--N 115
Cdd:PLN02776  20 LGSGEAIDLPGLGWTCAGTMLCAASANTLNQVFEVKNDSKMKRTMRRPLPSGRISVPHA-VAWAVVVGAAGVALLAYktN 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 535134085 116 TMTILLSIA-ALALAWVYPFMKRyTHLPQVVLGAAFGwSIP--MAFAAVSESVPLSCWLMFLANILWAVAYDTQYAMVDR 192
Cdd:PLN02776  99 MLTAGLGAGnILLYAFVYTPLKQ-IHPANTWVGAVVG-AIPplMGWAAASGQLDAGAMVLAAALYFWQMPHFMALAYMCR 176


                 ....*....
gi 535134085 193 DDDVKIGIK 201
Cdd:PLN02776 177 DDYAAGGYR 185
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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