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Conserved domains on  [gi|536036476|gb|ERB35268|]
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Iron(3+)-hydroxamate import ATP-binding protein FhuC [Escherichia coli UMEA 3271-1]

Protein Classification

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC( domain architecture ID 11484807)

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC is the ATPase subunit of the ABC transporter complex FhuCDB involved in iron(3+)-hydroxamate import and is responsible for energy coupling to the transport system

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK10575 PRK10575
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
1-265 0e+00

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;


:

Pssm-ID: 182561 [Multi-domain]  Cd Length: 265  Bit Score: 567.49  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   1 MQEYTNHSDTTFALRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSS 80
Cdd:PRK10575   1 MQEYTNHSDTTFALRNVSFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  81 KAFARKVAYLPQQLPPAEGMTVRELVAIGRYPWHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAM 160
Cdd:PRK10575  81 KAFARKVAYLPQQLPAAEGMTVRELVAIGRYPWHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAM 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 161 LVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMRGET 240
Cdd:PRK10575 161 LVAQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAELMRGET 240

                        250       260
                 ....*....|....*....|....*
gi 536036476 241 LEMIYGIPMGILPHPAGAAPVSFVY 265
Cdd:PRK10575 241 LEQIYGIPMGILPHPAGAAPVSFVY 265
 
Name Accession Description Interval E-value
PRK10575 PRK10575
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
1-265 0e+00

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;


Pssm-ID: 182561 [Multi-domain]  Cd Length: 265  Bit Score: 567.49  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   1 MQEYTNHSDTTFALRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSS 80
Cdd:PRK10575   1 MQEYTNHSDTTFALRNVSFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  81 KAFARKVAYLPQQLPPAEGMTVRELVAIGRYPWHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAM 160
Cdd:PRK10575  81 KAFARKVAYLPQQLPAAEGMTVRELVAIGRYPWHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAM 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 161 LVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMRGET 240
Cdd:PRK10575 161 LVAQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAELMRGET 240

                        250       260
                 ....*....|....*....|....*
gi 536036476 241 LEMIYGIPMGILPHPAGAAPVSFVY 265
Cdd:PRK10575 241 LEQIYGIPMGILPHPAGAAPVSFVY 265
FepC COG1120
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...
 12-261 3.54e-135

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];


Pssm-ID: 440737 [Multi-domain]  Cd Length: 254  Bit Score: 381.31  E-value: 3.54e-135
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  12 FALRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLP 91
Cdd:COG1120    2 LEAENLSVGYGGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLASLSRRELARRIAYVP 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  92 QQLPPAEGMTVRELVAIGRYPWHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLL 171
Cdd:COG1120   82 QEPPAPFGLTVRELVALGRYPHLGLFGRPSAEDREAVEEALERTGLEHLADRPVDELSGGERQRVLIARALAQEPPLLLL 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 172 DEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMRGETLEMIYGIPMGI 251
Cdd:COG1120  162 DEPTSHLDLAHQLEVLELLRRLARERGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGPPEEVLTPELLEEVYGVEARV 241

                        250
                 ....*....|
gi 536036476 252 LPHPAGAAPV 261
Cdd:COG1120  242 IEDPVTGRPL 251
ABC_Iron-Siderophores_B12_Hemin cd03214
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...
 13-230 6.43e-91

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.


Pssm-ID: 213181 [Multi-domain]  Cd Length: 180  Bit Score: 266.61  E-value: 6.43e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  13 ALRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQ 92
Cdd:cd03214    1 EVENLSVGYGGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASLSPKELARKIAYVPQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  93 qlppaegmtvrelvaigrypwhgalgrfgaadrekveeAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLD 172
Cdd:cd03214   81 --------------------------------------ALELLGLAHLADRPFNELSGGERQRVLLARALAQEPPILLLD 122

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 536036476 173 EPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQG 230
Cdd:cd03214  123 EPTSHLDIAHQIELLELLRRLARERGKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
20-213 6.94e-51

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 165.10  E-value: 6.94e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  20 RVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEIlldaqpleswsSKAFARKVAYLPQQ--LPPA 97
Cdd:NF040873   1 GYGGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTV-----------RRAGGARVAYVPQRseVPDS 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  98 EGMTVRELVAIGRYPWHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSA 177
Cdd:NF040873  70 LPLTVRDLVAMGRWARRGLWRRLTRDDRAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTG 149

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 536036476 178 LDIAHQVDVLSLVHRLSqERGLTVIAVLHDINMAAR 213
Cdd:NF040873 150 LDAESRERIIALLAEEH-ARGATVVVVTHDLELVRR 184
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 27-176 4.39e-45

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 148.56  E-value: 4.39e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   27 LHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQQLPPAEGMTVRELV 106
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERKSLRKEIGYVFQDPQLFPRLTVRENL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 536036476  107 AIGRYPWhgalGRFGAADREKVEEAISLVGLKPLAHRLVD----SLSGGERQRAWIAMLVAQDSRCLLLDEPTS 176
Cdd:pfam00005  81 RLGLLLK----GLSKREKDARAEEALEKLGLGDLADRPVGerpgTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
ECF_ATPase_2 TIGR04521
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 14-242 6.98e-44

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275314 [Multi-domain]  Cd Length: 277  Bit Score: 149.52  E-value: 6.98e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   14 LRNISFR-VPG----RTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQ---PLESWSSKAFAR 85
Cdd:TIGR04521   3 LKNVSYIyQPGtpfeKKALDDVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGLLKPTSGTVTIDGRditAKKKKKLKDLRK 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   86 KVAYLPQ----QLpPAEgmTVRELVAIGrypwhgaLGRFGAAD---REKVEEAISLVGLKP-LAHRLVDSLSGGERQRAW 157
Cdd:TIGR04521  83 KVGLVFQfpehQL-FEE--TVYKDIAFG-------PKNLGLSEeeaEERVKEALELVGLDEeYLERSPFELSGGQMRRVA 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  158 IAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEI-M 236
Cdd:TIGR04521 153 IAGVLAMEPEVLILDEPTAGLDPKGRKEILDLFKRLHKEKGLTVILVTHSMEDVAEYADRVIVMHKGKIVLDGTPREVfS 232


                  ....*.
gi 536036476  237 RGETLE 242
Cdd:TIGR04521 233 DVDELE 238
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
31-242 2.28e-18

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 84.41  E-value: 2.28e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  31 SLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESwSSKAFARKVAYLPQQLPPAEGMTVRE-LVAig 109
Cdd:NF033858 286 SFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPVDA-GDIATRRRVGYMSQAFSLYGELTVRQnLEL-- 362

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 110 rypwHGALGRFGAADREK-VEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLS 188
Cdd:NF033858 363 ----HARLFHLPAAEIAArVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSGVDPVARDMFWR 438

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 536036476 189 LVHRLSQERGLTVIAVLHDINMAARyCDYLVALRGGEMIAQGTPAEIMR---GETLE 242
Cdd:NF033858 439 LLIELSREDGVTIFISTHFMNEAER-CDRISLMHAGRVLASDTPAALVAargAATLE 494
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
14-242 5.13e-18

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 83.25  E-value: 5.13e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLG---RHQppsEGEI-LLDAQPLESWSSKAFARKVAY 89
Cdd:NF033858   4 LEGVSHRYGKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAgarKIQ---QGRVeVLGGDMADARHRRAVCPRIAY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  90 LPQQLppaeG------MTVRELVAigrypWHGALgrFG--AADRE-KVEEAISLVGLKPLAHRLVDSLSGGERQR----- 155
Cdd:NF033858  81 MPQGL----GknlyptLSVFENLD-----FFGRL--FGqdAAERRrRIDELLRATGLAPFADRPAGKLSGGMKQKlglcc 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 156 AWIamlvaQDSRCLLLDEPTSAldiahqVDVLS------LVHRLSQER-GLTVIAVLHDINMAARYcDYLVALRGGEMIA 228
Cdd:NF033858 150 ALI-----HDPDLLILDEPTTG------VDPLSrrqfweLIDRIRAERpGMSVLVATAYMEEAERF-DWLVAMDAGRVLA 217

                        250
                 ....*....|....*..
gi 536036476 229 QGTPAEIMR---GETLE 242
Cdd:NF033858 218 TGTPAELLArtgADTLE 234
GguA NF040905
sugar ABC transporter ATP-binding protein;
14-243 1.78e-14

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 72.51  E-value: 1.78e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKML-GRHQPPS-EGEILLDAQPLEswsskaF-------A 84
Cdd:NF040905   4 MRGITKTFPGVKALDDVNLSVREGEIHALCGENGAGKSTLMKVLsGVYPHGSyEGEILFDGEVCR------FkdirdseA 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  85 RKVAYLPQQLPPAEGMTVRELVAIGRYPwhgalGRFGAADREKV-EEAISL---VGLKPLAHRLVDSLSGGERQRAWIAM 160
Cdd:NF040905  78 LGIVIIHQELALIPYLSIAENIFLGNER-----AKRGVIDWNETnRRARELlakVGLDESPDTLVTDIGVGKQQLVEIAK 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 161 LVAQDSRCLLLDEPTSAL---DIAHqvdVLSLVHRLsQERGLTVIAVLHDINMAARYCDYLVALRGGEMIaqgtpaeimr 237
Cdd:NF040905 153 ALSKDVKLLILDEPTAALneeDSAA---LLDLLLEL-KAQGITSIIISHKLNEIRRVADSITVLRDGRTI---------- 218


                 ....*.
gi 536036476 238 gETLEM 243
Cdd:NF040905 219 -ETLDC 223
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 37-209 1.83e-08

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 52.38  E-value: 1.83e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476    37 GKVTGLIGHNGSGKSTLLKMLGRH-QPPSEGEILLDAqpleswsskafarkvaylpqqlppaegmtvrelvaigrypwhg 115
Cdd:smart00382   2 GEVILIVGPPGSGKTTLARALARElGPPGGGVIYIDG------------------------------------------- 38

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   116 algrfgaadrEKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVH---- 191
Cdd:smart00382  39 ----------EDILEEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLLEElrll 108

                          170
                   ....*....|....*....
gi 536036476   192 -RLSQERGLTVIAVLHDIN 209
Cdd:smart00382 109 lLLKSEKNLTVILTTNDEK 127
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
125-243 6.06e-04

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 40.49  E-value: 6.06e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 125 REKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQErGLTVIAV 204
Cdd:NF000106 122 RARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMVRD-GATVLLT 200

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 536036476 205 LHDINMAARYCDYLVALRGGEMIAQGTPAEI---MRGETLEM 243
Cdd:NF000106 201 TQYMEEAEQLAHELTVIDRGRVIADGKVDELktkVGGRTLQI 242
 
Name Accession Description Interval E-value
PRK10575 PRK10575
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
1-265 0e+00

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;


Pssm-ID: 182561 [Multi-domain]  Cd Length: 265  Bit Score: 567.49  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   1 MQEYTNHSDTTFALRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSS 80
Cdd:PRK10575   1 MQEYTNHSDTTFALRNVSFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  81 KAFARKVAYLPQQLPPAEGMTVRELVAIGRYPWHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAM 160
Cdd:PRK10575  81 KAFARKVAYLPQQLPAAEGMTVRELVAIGRYPWHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAM 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 161 LVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMRGET 240
Cdd:PRK10575 161 LVAQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAELMRGET 240

                        250       260
                 ....*....|....*....|....*
gi 536036476 241 LEMIYGIPMGILPHPAGAAPVSFVY 265
Cdd:PRK10575 241 LEQIYGIPMGILPHPAGAAPVSFVY 265
FepC COG1120
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...
 12-261 3.54e-135

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];


Pssm-ID: 440737 [Multi-domain]  Cd Length: 254  Bit Score: 381.31  E-value: 3.54e-135
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  12 FALRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLP 91
Cdd:COG1120    2 LEAENLSVGYGGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLASLSRRELARRIAYVP 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  92 QQLPPAEGMTVRELVAIGRYPWHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLL 171
Cdd:COG1120   82 QEPPAPFGLTVRELVALGRYPHLGLFGRPSAEDREAVEEALERTGLEHLADRPVDELSGGERQRVLIARALAQEPPLLLL 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 172 DEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMRGETLEMIYGIPMGI 251
Cdd:COG1120  162 DEPTSHLDLAHQLEVLELLRRLARERGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGPPEEVLTPELLEEVYGVEARV 241

                        250
                 ....*....|
gi 536036476 252 LPHPAGAAPV 261
Cdd:COG1120  242 IEDPVTGRPL 251
CeuD COG4604
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ...
 14-255 3.49e-108

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443654 [Multi-domain]  Cd Length: 252  Bit Score: 312.79  E-value: 3.49e-108
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQQ 93
Cdd:COG4604    4 IKNVSKRYGGKVVLDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGLDVATTPSRELAKRLAILRQE 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  94 LPPAEGMTVRELVAIGRYPWHGalGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDE 173
Cdd:COG4604   84 NHINSRLTVRELVAFGRFPYSK--GRLTAEDREIIDEAIAYLDLEDLADRYLDELSGGQRQRAFIAMVLAQDTDYVLLDE 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 174 PTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMRGETLEMIYGIPMGILP 253
Cdd:COG4604  162 PLNNLDMKHSVQMMKLLRRLADELGKTVVIVLHDINFASCYADHIVAMKDGRVVAQGTPEEIITPEVLSDIYDTDIEVEE 241


                 ..
gi 536036476 254 HP 255
Cdd:COG4604  242 ID 243
fecE PRK11231
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
24-260 8.20e-99

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;


Pssm-ID: 183044 [Multi-domain]  Cd Length: 255  Bit Score: 289.22  E-value: 8.20e-99
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  24 RTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQQLPPAEGMTVR 103
Cdd:PRK11231  15 KRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMLSSRQLARRLALLPQHHLTPEGITVR 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 104 ELVAIGRYPWHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQ 183
Cdd:PRK11231  95 ELVAYGRSPWLSLWGRLSAEDNARVNQAMEQTRINHLADRRLTDLSGGQRQRAFLAMVLAQDTPVVLLDEPTTYLDINHQ 174

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 536036476 184 VDVLSLVHRLSQErGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMRGETLEMIYGIPMGILPHPAGAAP 260
Cdd:PRK11231 175 VELMRLMRELNTQ-GKTVVTVLHDLNQASRYCDHLVVLANGHVMAQGTPEEVMTPGLLRTVFDVEAEIHPEPVSGTP 250
COG4559 COG4559
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
15-261 4.21e-94

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443620 [Multi-domain]  Cd Length: 258  Bit Score: 277.38  E-value: 4.21e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  15 RNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQQL 94
Cdd:COG4559    5 ENLSVRLGGRTLLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRLNGRPLAAWSPWELARRRAVLPQHS 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  95 PPAEGMTVRELVAIGRYPWhgalGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQ-------DSR 167
Cdd:COG4559   85 SLAFPFTVEEVVALGRAPH----GSSAAQDRQIVREALALVGLAHLAGRSYQTLSGGEQQRVQLARVLAQlwepvdgGPR 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 168 CLLLDEPTSALDIAHQVDVLSLVHRLSQeRGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMRGETLEMIYGI 247
Cdd:COG4559  161 WLFLDEPTSALDLAHQHAVLRLARQLAR-RGGGVVAVLHDLNLAAQYADRILLLHQGRLVAQGTPEEVLTDELLERVYGA 239

                        250
                 ....*....|....
gi 536036476 248 PMGILPHPAGAAPV 261
Cdd:COG4559  240 DLRVLAHPEGGCPQ 253
hmuV PRK13548
hemin importer ATP-binding subunit; Provisional
 15-261 7.46e-93

hemin importer ATP-binding subunit; Provisional


Pssm-ID: 237422 [Multi-domain]  Cd Length: 258  Bit Score: 274.34  E-value: 7.46e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  15 RNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQQL 94
Cdd:PRK13548   6 RNLSVRLGGRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLADWSPAELARRRAVLPQHS 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  95 PPAEGMTVRELVAIGRYPWhgalGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQ------DSRC 168
Cdd:PRK13548  86 SLSFPFTVEEVVAMGRAPH----GLSRAEDDALVAAALAQVDLAHLAGRDYPQLSGGEQQRVQLARVLAQlwepdgPPRW 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 169 LLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMRGETLEMIYGIP 248
Cdd:PRK13548 162 LLLDEPTSALDLAHQHHVLRLARQLAHERGLAVIVVLHDLNLAARYADRIVLLHQGRLVADGTPAEVLTPETLRRVYGAD 241

                        250
                 ....*....|...
gi 536036476 249 MGILPHPAGAAPV 261
Cdd:PRK13548 242 VLVQPHPETGAPL 254
ABC_Iron-Siderophores_B12_Hemin cd03214
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...
 13-230 6.43e-91

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.


Pssm-ID: 213181 [Multi-domain]  Cd Length: 180  Bit Score: 266.61  E-value: 6.43e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  13 ALRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQ 92
Cdd:cd03214    1 EVENLSVGYGGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASLSPKELARKIAYVPQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  93 qlppaegmtvrelvaigrypwhgalgrfgaadrekveeAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLD 172
Cdd:cd03214   81 --------------------------------------ALELLGLAHLADRPFNELSGGERQRVLLARALAQEPPILLLD 122

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 536036476 173 EPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQG 230
Cdd:cd03214  123 EPTSHLDIAHQIELLELLRRLARERGKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180
ZnuC COG1121
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 14-254 2.22e-82

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440738 [Multi-domain]  Cd Length: 245  Bit Score: 247.31  E-value: 2.22e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLK-MLGRHqPPSEGEILLDAQPLeswssKAFARKVAYLPQ 92
Cdd:COG1121    9 LENLTVSYGGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKaILGLL-PPTSGTVRLFGKPP-----RRARRRIGYVPQ 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  93 Q------LPpaegMTVRELVAIGRYPWHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDS 166
Cdd:COG1121   83 RaevdwdFP----ITVRDVVLMGRYGRRGLFRRPSRADREAVDEALERVGLEDLADRPIGELSGGQQQRVLLARALAQDP 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 167 RCLLLDEPTSALDIAHQVDVLSLVHRLSQErGLTVIAVLHDINMAARYCDYLVALRGGeMIAQGTPAEIMRGETLEMIYG 246
Cdd:COG1121  159 DLLLLDEPFAGVDAATEEALYELLRELRRE-GKTILVVTHDLGAVREYFDRVLLLNRG-LVAHGPPEEVLTPENLSRAYG 236


                 ....*...
gi 536036476 247 IPMGILPH 254
Cdd:COG1121  237 GPVALLAH 244
PRK10253 PRK10253
iron-enterobactin ABC transporter ATP-binding protein;
24-261 1.95e-74

iron-enterobactin ABC transporter ATP-binding protein;


Pssm-ID: 182336 [Multi-domain]  Cd Length: 265  Bit Score: 227.95  E-value: 1.95e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  24 RTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQQLPPAEGMTVR 103
Cdd:PRK10253  20 YTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEVARRIGLLAQNATTPGDITVQ 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 104 ELVAIGRYPWHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQ 183
Cdd:PRK10253 100 ELVARGRYPHQPLFTRWRKEDEEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQETAIMLLDEPTTWLDISHQ 179

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 536036476 184 VDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMRGETLEMIYGIPMGILPHPAGAAPV 261
Cdd:PRK10253 180 IDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALREGKIVAQGAPKEIVTAELIERIYGLRCMIIDDPVAGTPL 257
ABC_Metallic_Cations cd03235
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...
 16-230 1.06e-67

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.


Pssm-ID: 213202 [Multi-domain]  Cd Length: 213  Bit Score: 208.54  E-value: 1.06e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  16 NISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLK-MLGRHqPPSEGEILLDAQPLESWSskafaRKVAYLPQQL 94
Cdd:cd03235    4 DLTVSYGGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKaILGLL-KPTSGSIRVFGKPLEKER-----KRIGYVPQRR 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  95 ------PpaegMTVRELVAIGRYPWHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRC 168
Cdd:cd03235   78 sidrdfP----ISVRDVVLMGLYGHKGLFRRLSKADKAKVDEALERVGLSELADRQIGELSGGQQQRVLLARALVQDPDL 153

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 536036476 169 LLLDEPTSALDIAHQVDVLSLVHRLsQERGLTVIAVLHDINMAARYCDYlVALRGGEMIAQG 230
Cdd:cd03235  154 LLLDEPFAGVDPKTQEDIYELLREL-RREGMTILVVTHDLGLVLEYFDR-VLLLNRTVVASG 213
EcfA2 COG1122
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...
 12-242 5.03e-64

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];


Pssm-ID: 440739 [Multi-domain]  Cd Length: 230  Bit Score: 199.87  E-value: 5.03e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  12 FALRNISFRVP-GRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYL 90
Cdd:COG1122    1 IELENLSFSYPgGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITKKNLRELRRKVGLV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  91 PQ----QLppaEGMTVRELVAIGrypwhgaLGRFGAAD---REKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVA 163
Cdd:COG1122   81 FQnpddQL---FAPTVEEDVAFG-------PENLGLPReeiRERVEEALELVGLEHLADRPPHELSGGQKQRVAIAGVLA 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 164 QDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQErGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIM-RGETLE 242
Cdd:COG1122  151 MEPEVLVLDEPTAGLDPRGRRELLELLKRLNKE-GKTVIIVTHDLDLVAELADRVIVLDDGRIVADGTPREVFsDYELLE 229
btuD PRK09536
corrinoid ABC transporter ATPase; Reviewed
 11-260 2.13e-60

corrinoid ABC transporter ATPase; Reviewed


Pssm-ID: 236554 [Multi-domain]  Cd Length: 402  Bit Score: 196.22  E-value: 2.13e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  11 TFALRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYL 90
Cdd:PRK09536   3 MIDVSDLSVEFGDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEALSARAASRRVASV 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  91 PQQLPPAEGMTVRELVAIGRYPWHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLL 170
Cdd:PRK09536  83 PQDTSLSFEFDVRQVVEMGRTPHRSRFDTWTETDRAAVERAMERTGVAQFADRPVTSLSGGERQRVLLARALAQATPVLL 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 171 LDEPTSALDIAHQVDVLSLVHRLSQErGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMRGETLEMIYGIPMG 250
Cdd:PRK09536 163 LDEPTASLDINHQVRTLELVRRLVDD-GKTAVAAIHDLDLAARYCDELVLLADGRVRAAGPPADVLTADTLRAAFDARTA 241

                        250
                 ....*....|
gi 536036476 251 ILPHPAGAAP 260
Cdd:PRK09536 242 VGTDPATGAP 251
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
14-245 1.03e-58

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 186.42  E-value: 1.03e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARkVAYLPQQ 93
Cdd:COG1131    3 VRGLTKRYGDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVARDPAEVRRR-IGYVPQE 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  94 LPPAEGMTVRELVAIgrypwHGAL-GRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLD 172
Cdd:COG1131   82 PALYPDLTVRENLRF-----FARLyGLPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPELLILD 156

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 536036476 173 EPTSALDIAHQVDVLSLVHRLSqERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMRgETLEMIY 245
Cdd:COG1131  157 EPTSGLDPEARRELWELLRELA-AEGKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDELKA-RLLEDVF 227
ABC_cobalt_CbiO_domain1 cd03225
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...
 14-225 4.48e-58

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213192 [Multi-domain]  Cd Length: 211  Bit Score: 184.21  E-value: 4.48e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPG--RTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLP 91
Cdd:cd03225    2 LKNLSFSYPDgaRPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLSLKELRRKVGLVF 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  92 QQlppAEGM----TVRELVAIGRypwhGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSR 167
Cdd:cd03225   82 QN---PDDQffgpTVEEEVAFGL----ENLGLPEEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPD 154

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 536036476 168 CLLLDEPTSALDIAHQVDVLSLVHRLsQERGLTVIAVLHDINMAARYCDYLVALRGGE 225
Cdd:cd03225  155 ILLLDEPTAGLDPAGRRELLELLKKL-KAEGKTIIIVTHDLDLLLELADRVIVLEDGK 211
ABC_PhnC_transporter cd03256
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...
 12-245 8.96e-58

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213223 [Multi-domain]  Cd Length: 241  Bit Score: 184.31  E-value: 8.96e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  12 FALRNISFRVP-GRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKA---FARKV 87
Cdd:cd03256    1 IEVENLSKTYPnGKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINKLKGKAlrqLRRQI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  88 AYLPQQLPPAEGMTVRELVAIGRYP----WHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVA 163
Cdd:cd03256   81 GMIFQQFNLIERLSVLENVLSGRLGrrstWRSLFGLFPKEEKQRALAALERVGLLDKAYQRADQLSGGQQQRVAIARALM 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 164 QDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMRgETLEM 243
Cdd:cd03256  161 QQPKLILADEPVASLDPASSRQVMDLLKRINREEGITVIVSLHQVDLAREYADRIVGLKDGRIVFDGPPAELTD-EVLDE 239


                 ..
gi 536036476 244 IY 245
Cdd:cd03256  240 IY 241
FetA COG4619
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
12-226 2.15e-57

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443661 [Multi-domain]  Cd Length: 209  Bit Score: 182.32  E-value: 2.15e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  12 FALRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLP 91
Cdd:COG4619    1 LELEGLSFRVGGKPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPLSAMPPPEWRRQVAYVP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  92 QQlPPAEGMTVRELVaigRYPWHGALGRFgaaDREKVEEAISLVGLKP-LAHRLVDSLSGGERQRAWIAMLVAQDSRCLL 170
Cdd:COG4619   81 QE-PALWGGTVRDNL---PFPFQLRERKF---DRERALELLERLGLPPdILDKPVERLSGGERQRLALIRALLLQPDVLL 153

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 536036476 171 LDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEM 226
Cdd:COG4619  154 LDEPTSALDPENTRRVEELLREYLAEEGRAVLWVSHDPEQIERVADRVLTLEAGRL 209
BtuD COG4138
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ...
 13-248 5.44e-57

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];


Pssm-ID: 443313 [Multi-domain]  Cd Length: 248  Bit Score: 182.35  E-value: 5.44e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  13 ALRNISfrVPGRtlLHPLSLTFPAGKVTGLIGHNGSGKSTLL-KMLGRHqpPSEGEILLDAQPLESWSSKAFARKVAYLP 91
Cdd:COG4138    2 QLNDVA--VAGR--LGPISAQVNAGELIHLIGPNGAGKSTLLaRMAGLL--PGQGEILLNGRPLSDWSAAELARHRAYLS 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  92 QQLPPAEGMTVrelvaigrypWHG-ALGRFGAADREKVEEAISLV----GLKPLAHRLVDSLSGGERQRAWIAMLVAQ-- 164
Cdd:COG4138   76 QQQSPPFAMPV----------FQYlALHQPAGASSEAVEQLLAQLaealGLEDKLSRPLTQLSGGEWQRVRLAAVLLQvw 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 165 -----DSRCLLLDEPTSALDIAHQVDVLSLVHRLSQeRGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMRGE 239
Cdd:COG4138  146 ptinpEGQLLLLDEPMNSLDVAQQAALDRLLRELCQ-QGITVVMSSHDLNHTLRHADRVWLLKQGKLVASGETAEVMTPE 224


                 ....*....
gi 536036476 240 TLEMIYGIP 248
Cdd:COG4138  225 NLSEVFGVK 233
hmuV PRK13547
heme ABC transporter ATP-binding protein;
23-261 1.38e-56

heme ABC transporter ATP-binding protein;


Pssm-ID: 184132 [Multi-domain]  Cd Length: 272  Bit Score: 182.33  E-value: 1.38e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  23 GRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPS--------EGEILLDAQPLESWSSKAFARKVAYLPQQL 94
Cdd:PRK13547  13 HRAILRDLSLRIEPGRVTALLGRNGAGKSTLLKALAGDLTGGgaprgarvTGDVTLNGEPLAAIDAPRLARLRAVLPQAA 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  95 PPAEGMTVRELVAIGRYPWHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQ---------D 165
Cdd:PRK13547  93 QPAFAFSAREIVLLGRYPHARRAGALTHRDGEIAWQALALAGATALVGRDVTTLSGGELARVQFARVLAQlwpphdaaqP 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 166 SRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMRGETLEMIY 245
Cdd:PRK13547 173 PRYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLGVLAIVHDPNLAARHADRIAMLADGAIVAHGAPADVLTPAHIARCY 252

                        250
                 ....*....|....*.
gi 536036476 246 GIPMGILPHPAGAAPV 261
Cdd:PRK13547 253 GFAVRLVDAGDGVPPV 268
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 14-237 7.29e-56

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 187.03  E-value: 7.29e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGR-----TLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSS---KAFAR 85
Cdd:COG1123  263 VRNLSKRYPVRgkggvRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKDLTKLSRrslRELRR 342

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  86 KVAYLPQ----QLPPAegMTVRELVAigrYPWHgALGRFGAADR-EKVEEAISLVGLKP-LAHRLVDSLSGGERQRAWIA 159
Cdd:COG1123  343 RVQMVFQdpysSLNPR--MTVGDIIA---EPLR-LHGLLSRAERrERVAELLERVGLPPdLADRYPHELSGGQRQRVAIA 416

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 536036476 160 MLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMR 237
Cdd:COG1123  417 RALALEPKLLILDEPTSALDVSVQAQILNLLRDLQRELGLTYLFISHDLAVVRYIADRVAVMYDGRIVEDGPTEEVFA 494
NatA COG4555
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...
 14-242 6.65e-53

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 443618 [Multi-domain]  Cd Length: 243  Bit Score: 171.96  E-value: 6.65e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFaRKVAYLPQQ 93
Cdd:COG4555    4 VENLSKKYGKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDVRKEPREAR-RQIGVLPDE 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  94 LPPAEGMTVRELVaigRYpwHGAL-GRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLD 172
Cdd:COG4555   83 RGLYDRLTVRENI---RY--FAELyGLFDEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPKVLLLD 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 173 EPTSALDIAHQVDVLSLVHRLSQErGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMRGETLE 242
Cdd:COG4555  158 EPTNGLDVMARRLLREILRALKKE-GKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDELREEIGEE 226
DppF COG1124
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 14-238 1.70e-52

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440741 [Multi-domain]  Cd Length: 248  Bit Score: 171.14  E-value: 1.70e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVP----GRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAY 89
Cdd:COG1124    4 VRNLSVSYGqggrRVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPVTRRRRKAFRRRVQM 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  90 LPQQ----LPPaeGMTVRELVAigrYPWHgALGRFGAADRekVEEAISLVGLKP-LAHRLVDSLSGGERQRAWIAMLVAQ 164
Cdd:COG1124   84 VFQDpyasLHP--RHTVDRILA---EPLR-IHGLPDREER--IAELLEQVGLPPsFLDRYPHQLSGGQRQRVAIARALIL 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 536036476 165 DSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMRG 238
Cdd:COG1124  156 EPELLLLDEPTSALDVSVQAEILNLLKDLREERGLTYLFVSHDLAVVAHLCDRVAVMQNGRIVEELTVADLLAG 229
ABC_Mj1267_LivG_branched cd03219
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...
 30-237 7.75e-52

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).


Pssm-ID: 213186 [Multi-domain]  Cd Length: 236  Bit Score: 168.77  E-value: 7.75e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  30 LSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARK-VAYLPQQLPPAEGMTVRELVAI 108
Cdd:cd03219   19 VSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDITGLPPHEIARLgIGRTFQIPRLFPELTVLENVMV 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 109 GRYPWHGALGRFG------AADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAH 182
Cdd:cd03219   99 AAQARTGSGLLLArarreeREARERAEELLERVGLADLADRPAGELSYGQQRRLEIARALATDPKLLLLDEPAAGLNPEE 178

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 536036476 183 QVDVLSLVHRLSqERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMR 237
Cdd:cd03219  179 TEELAELIRELR-ERGITVLLVEHDMDVVMSLADRVTVLDQGRVIAEGTPDEVRN 232
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
20-213 6.94e-51

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 165.10  E-value: 6.94e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  20 RVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEIlldaqpleswsSKAFARKVAYLPQQ--LPPA 97
Cdd:NF040873   1 GYGGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTV-----------RRAGGARVAYVPQRseVPDS 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  98 EGMTVRELVAIGRYPWHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSA 177
Cdd:NF040873  70 LPLTVRDLVAMGRWARRGLWRRLTRDDRAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTG 149

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 536036476 178 LDIAHQVDVLSLVHRLSqERGLTVIAVLHDINMAAR 213
Cdd:NF040873 150 LDAESRERIIALLAEEH-ARGATVVVVTHDLELVRR 184
LivG COG0411
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ...
 8-237 2.61e-50

ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];


Pssm-ID: 440180 [Multi-domain]  Cd Length: 257  Bit Score: 165.60  E-value: 2.61e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   8 SDTTFALRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARK- 86
Cdd:COG0411    1 SDPLLEVRGLTKRFGGLVAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDGRDITGLPPHRIARLg 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  87 VAYLPQQLPPAEGMTVRELVAIG-----RYPWHGALGRFG------AADREKVEEAISLVGLKPLAHRLVDSLSGGERQR 155
Cdd:COG0411   81 IARTFQNPRLFPELTVLENVLVAaharlGRGLLAALLRLPrarreeREARERAEELLERVGLADRADEPAGNLSYGQQRR 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 156 AWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEI 235
Cdd:COG0411  161 LEIARALATEPKLLLLDEPAAGLNPEETEELAELIRRLRDERGITILLIEHDMDLVMGLADRIVVLDFGRVIAEGTPAEV 240


                 ..
gi 536036476 236 MR 237
Cdd:COG0411  241 RA 242
CydD COG4988
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...
 2-237 1.31e-47

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444012 [Multi-domain]  Cd Length: 563  Bit Score: 166.09  E-value: 1.31e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   2 QEYTNHSDTTFALRNISFRVP-GRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSS 80
Cdd:COG4988  327 APLPAAGPPSIELEDVSFSYPgGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDLSDLDP 406

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  81 KAFARKVAYLPQQ--LPPAegmTVRELVAIGRypwhgalgrfGAADREKVEEAISLVGLKPLAHRLVD-----------S 147
Cdd:COG4988  407 ASWRRQIAWVPQNpyLFAG---TIRENLRLGR----------PDASDEELEAALEAAGLDEFVAALPDgldtplgeggrG 473

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 148 LSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERglTVIAVLHDINMAARyCDYLVALRGGEMI 227
Cdd:COG4988  474 LSGGQAQRLALARALLRDAPLLLLDEPTAHLDAETEAEILQALRRLAKGR--TVILITHRLALLAQ-ADRILVLDDGRIV 550

                        250
                 ....*....|
gi 536036476 228 AQGTPAEIMR 237
Cdd:COG4988  551 EQGTHEELLA 560
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
 3-225 1.45e-47

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 157.27  E-value: 1.45e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   3 EYTNHSDTTFALRNISFRVPgrtllhplsltfpAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKA 82
Cdd:cd03255    9 TYGGGGEKVQALKGVSLSIE-------------KGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSEKE 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  83 FA----RKVAYLPQQ---LPpaeGMTVRELVAIgryPWHGAlGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQR 155
Cdd:cd03255   76 LAafrrRHIGFVFQSfnlLP---DLTALENVEL---PLLLA-GVPKKERRERAEELLERVGLGDRLNHYPSELSGGQQQR 148

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 156 AWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMaARYCDYLVALRGGE 225
Cdd:cd03255  149 VAIARALANDPKIILADEPTGNLDSETGKEVMELLRELNKEAGTTIVVVTHDPEL-AEYADRIIELRDGK 217
CcmA COG4133
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...
 14-203 3.62e-47

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443308 [Multi-domain]  Cd Length: 206  Bit Score: 156.10  E-value: 3.62e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSkAFARKVAYLPQQ 93
Cdd:COG4133    5 AENLSCRRGERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRDARE-DYRRRLAYLGHA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  94 LPPAEGMTVRELVAIgrypWHGALGRfgAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDE 173
Cdd:COG4133   84 DGLKPELTVRENLRF----WAALYGL--RADREAIDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAPLWLLDE 157

                        170       180       190
                 ....*....|....*....|....*....|
gi 536036476 174 PTSALDIAHQVDVLSLVHRLSQERGLTVIA 203
Cdd:COG4133  158 PFTALDAAGVALLAELIAAHLARGGAVLLT 187
ABC_Org_Solvent_Resistant cd03261
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...
 14-237 5.79e-47

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213228 [Multi-domain]  Cd Length: 235  Bit Score: 156.51  E-value: 5.79e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSK---AFARKVAYL 90
Cdd:cd03261    3 LRGLTKSFGGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGLSEAelyRLRRRMGML 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  91 PQQLPPAEGMTVRELVAigrYPW--HGALGRfgAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRC 168
Cdd:cd03261   83 FQSGALFDSLTVFENVA---FPLreHTRLSE--EEIREIVLEKLEAVGLRGAEDLYPAELSGGMKKRVALARALALDPEL 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 169 LLLDEPTSALD-IAHQVdVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMR 237
Cdd:cd03261  158 LLYDEPTAGLDpIASGV-IDDLIRSLKKELGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTPEELRA 226
MlaF COG1127
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...
 14-237 6.70e-47

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440744 [Multi-domain]  Cd Length: 241  Bit Score: 156.29  E-value: 6.70e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSK---AFARKVAYL 90
Cdd:COG1127    8 VRNLTKSFGDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDITGLSEKelyELRRRIGML 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  91 PQQlppaeG-----MTVRELVAIG-RYpwHGALGRfgAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQ 164
Cdd:COG1127   88 FQG-----GalfdsLTVFENVAFPlRE--HTDLSE--AEIRELVLEKLELVGLPGAADKMPSELSGGMRKRVALARALAL 158

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 536036476 165 DSRCLLLDEPTSALDI--AHQVDvlSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMR 237
Cdd:COG1127  159 DPEILLYDEPTAGLDPitSAVID--ELIRELRDELGLTSVVVTHDLDSAFAIADRVAVLADGKIIAEGTPEELLA 231
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 14-237 7.25e-47

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 163.15  E-value: 7.25e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPG--RTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPS---EGEILLDAQPLESWSSKAFARKVA 88
Cdd:COG1123    7 VRDLSVRYPGgdVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGgriSGEVLLDGRDLLELSEALRGRRIG 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  89 YLPQ----QLPPAegmTVRELVAIGRYpwhgALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQ 164
Cdd:COG1123   87 MVFQdpmtQLNPV---TVGDQIAEALE----NLGLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQRQRVAIAMALAL 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 536036476 165 DSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMR 237
Cdd:COG1123  160 DPDLLIADEPTTALDVTTQAEILDLLRELQRERGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPEEILA 232
PRK03695 PRK03695
vitamin B12-transporter ATPase; Provisional
 14-248 1.07e-46

vitamin B12-transporter ATPase; Provisional


Pssm-ID: 235150 [Multi-domain]  Cd Length: 248  Bit Score: 156.25  E-value: 1.07e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISfrVPGRtlLHPLSLTFPAGKVTGLIGHNGSGKSTLL-KMLGrhQPPSEGEILLDAQPLESWSSKAFARKVAYLPQ 92
Cdd:PRK03695   3 LNDVA--VSTR--LGPLSAEVRAGEILHLVGPNGAGKSTLLaRMAG--LLPGSGSIQFAGQPLEAWSAAELARHRAYLSQ 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  93 QLPPAEGMTVRELVAIgrypwHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQ-------D 165
Cdd:PRK03695  77 QQTPPFAMPVFQYLTL-----HQPDKTRTEAVASALNEVAEALGLDDKLGRSVNQLSGGEWQRVRLAAVVLQvwpdinpA 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 166 SRCLLLDEPTSALDIAHQVDVLSLVHRLSQErGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMRGETLEMIY 245
Cdd:PRK03695 152 GQLLLLDEPMNSLDVAQQAALDRLLSELCQQ-GIAVVMSSHDLNHTLRHADRVWLLKQGKLLASGRRDEVLTPENLAQVF 230


                 ...
gi 536036476 246 GIP 248
Cdd:PRK03695 231 GVN 233
ABC_NikE_OppD_transporters cd03257
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...
 16-230 2.18e-46

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.


Pssm-ID: 213224 [Multi-domain]  Cd Length: 228  Bit Score: 154.59  E-value: 2.18e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  16 NISFRVPGR--TLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSS---KAFARKVAYL 90
Cdd:cd03257    8 SVSFPTGGGsvKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLSRrlrKIRRKEIQMV 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  91 PQQ----LPPAegMTVRELVAIGRYPWHGALGRfgAADREKVEEAISLVGLKP-LAHRLVDSLSGGERQRAWIAMLVAQD 165
Cdd:cd03257   88 FQDpmssLNPR--MTIGEQIAEPLRIHGKLSKK--EARKEAVLLLLVGVGLPEeVLNRYPHELSGGQRQRVAIARALALN 163

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 536036476 166 SRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQG 230
Cdd:cd03257  164 PKLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGKIVEEG 228
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 27-176 4.39e-45

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 148.56  E-value: 4.39e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   27 LHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQQLPPAEGMTVRELV 106
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERKSLRKEIGYVFQDPQLFPRLTVRENL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 536036476  107 AIGRYPWhgalGRFGAADREKVEEAISLVGLKPLAHRLVD----SLSGGERQRAWIAMLVAQDSRCLLLDEPTS 176
Cdd:pfam00005  81 RLGLLLK----GLSKREKDARAEEALEKLGLGDLADRPVGerpgTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
14-229 5.78e-45

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 150.96  E-value: 5.78e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVP----GRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFA----R 85
Cdd:COG1136    7 LRNLTKSYGtgegEVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSLSERELArlrrR 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  86 KVAYLPQQ---LPpaeGMTVRELVAIGRYPwhgaLGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLV 162
Cdd:COG1136   87 HIGFVFQFfnlLP---ELTALENVALPLLL----AGVSRKERRERARELLERVGLGDRLDHRPSQLSGGQQQRVAIARAL 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 536036476 163 AQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAArYCDYLVALRGGEMIAQ 229
Cdd:COG1136  160 VNRPKLILADEPTGNLDSKTGEEVLELLRELNRELGTTIVMVTHDPELAA-RADRVIRLRDGRIVSD 225
CysA COG1118
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ...
 14-237 2.18e-44

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440735 [Multi-domain]  Cd Length: 348  Bit Score: 152.99  E-value: 2.18e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSkAFARKVAYLPQQ 93
Cdd:COG1118    5 VRNISKRFGSFTLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNGRDLFTNLP-PRERRVGFVFQH 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  94 --LPPAegMTVRELVAIG-RypwhgALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLL 170
Cdd:COG1118   84 yaLFPH--MTVAENIAFGlR-----VRPPSKAEIRARVEELLELVQLEGLADRYPSQLSGGQRQRVALARALAVEPEVLL 156

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 536036476 171 LDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMR 237
Cdd:COG1118  157 LDEPFGALDAKVRKELRRWLRRLHDELGGTTVFVTHDQEEALELADRVVVMNQGRIEQVGTPDEVYD 223
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
 14-225 2.22e-44

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 147.01  E-value: 2.22e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQq 93
Cdd:cd00267    2 IENLSFRYGGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKLPLEELRRRIGYVPQ- 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  94 lppaegmtvrelvaigrypwhgalgrfgaadrekveeaislvglkplahrlvdsLSGGERQRAWIAMLVAQDSRCLLLDE 173
Cdd:cd00267   81 ------------------------------------------------------LSGGQRQRVALARALLLNPDLLLLDE 106

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 536036476 174 PTSALDIAHQVDVLSLVHRLSQErGLTVIAVLHDINMAARYCDYLVALRGGE 225
Cdd:cd00267  107 PTSGLDPASRERLLELLRELAEE-GRTVIIVTHDPELAELAADRVIVLKDGK 157
ECF_ATPase_2 TIGR04521
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 14-242 6.98e-44

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275314 [Multi-domain]  Cd Length: 277  Bit Score: 149.52  E-value: 6.98e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   14 LRNISFR-VPG----RTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQ---PLESWSSKAFAR 85
Cdd:TIGR04521   3 LKNVSYIyQPGtpfeKKALDDVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGLLKPTSGTVTIDGRditAKKKKKLKDLRK 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   86 KVAYLPQ----QLpPAEgmTVRELVAIGrypwhgaLGRFGAAD---REKVEEAISLVGLKP-LAHRLVDSLSGGERQRAW 157
Cdd:TIGR04521  83 KVGLVFQfpehQL-FEE--TVYKDIAFG-------PKNLGLSEeeaEERVKEALELVGLDEeYLERSPFELSGGQMRRVA 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  158 IAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEI-M 236
Cdd:TIGR04521 153 IAGVLAMEPEVLILDEPTAGLDPKGRKEILDLFKRLHKEKGLTVILVTHSMEDVAEYADRVIVMHKGKIVLDGTPREVfS 232


                  ....*.
gi 536036476  237 RGETLE 242
Cdd:TIGR04521 233 DVDELE 238
ThiQ COG3840
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
14-244 7.63e-44

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];


Pssm-ID: 443051 [Multi-domain]  Cd Length: 232  Bit Score: 148.36  E-value: 7.63e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLlhPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSkaFARKVAYLPQQ 93
Cdd:COG3840    4 LDDLTYRYGDFPL--RFDLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQDLTALPP--AERPVSMLFQE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  94 --LPPAegMTVRELVAIGRYPwhgALgRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLL 171
Cdd:COG3840   80 nnLFPH--LTVAQNIGLGLRP---GL-KLTAEQRAQVEQALERVGLAGLLDRLPGQLSGGQRQRVALARCLVRKRPILLL 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 536036476 172 DEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMRGETLEMI 244
Cdd:COG3840  154 DEPFSALDPALRQEMLDLVDELCRERGLTVLMVTHDPEDAARIADRVLLVADGRIAADGPTAALLDGEPPPAL 226
ModF COG1119
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...
 9-248 8.38e-44

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];


Pssm-ID: 440736 [Multi-domain]  Cd Length: 250  Bit Score: 148.69  E-value: 8.38e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   9 DTTFALRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGE--ILLDaQPLESWSSKAFARK 86
Cdd:COG1119    1 DPLLELRNVTVRRGGKTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGNdvRLFG-ERRGGEDVWELRKR 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  87 VAY----LPQQLPPaeGMTVRELVAIGRYpwhGALGRF---GAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIA 159
Cdd:COG1119   80 IGLvspaLQLRFPR--DETVLDVVLSGFF---DSIGLYrepTDEQRERARELLELLGLAHLADRPFGTLSQGEQRRVLIA 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 160 -MLVAqDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMRG 238
Cdd:COG1119  155 rALVK-DPELLILDEPTAGLDLGARELLLALLDKLAAEGAPTLVLVTHHVEEIPPGITHVLLLKDGRVVAAGPKEEVLTS 233

                        250
                 ....*....|
gi 536036476 239 ETLEMIYGIP 248
Cdd:COG1119  234 ENLSEAFGLP 243
ABC_OpuCA_Osmoprotection cd03295
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...
 14-237 3.63e-43

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213262 [Multi-domain]  Cd Length: 242  Bit Score: 146.68  E-value: 3.63e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPG-RTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQ 92
Cdd:cd03295    3 FENVTKRYGGgKKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIREQDPVELRRKIGYVIQ 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  93 QLPPAEGMTVRELVAIgrYPwhGALGRFGAADREKVEEAISLVGLKP--LAHRLVDSLSGGERQRAWIAMLVAQDSRCLL 170
Cdd:cd03295   83 QIGLFPHMTVEENIAL--VP--KLLKWPKEKIRERADELLALVGLDPaeFADRYPHELSGGQQQRVGVARALAADPPLLL 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 536036476 171 LDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMR 237
Cdd:cd03295  159 MDEPFGALDPITRDQLQEEFKRLQQELGKTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPDEILR 225
ABC_PstB_phosphate_transporter cd03260
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...
 12-235 6.72e-43

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).


Pssm-ID: 213227 [Multi-domain]  Cd Length: 227  Bit Score: 145.79  E-value: 6.72e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  12 FALRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGR---HQP--PSEGEILLDAQPLESWSSKAFA-- 84
Cdd:cd03260    1 IELRDLNVYYGDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRlndLIPgaPDEGEVLLDGKDIYDLDVDVLElr 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  85 RKVAYLPQQLPPAEgMTVRELVAIGryPW-HGALGRFGAADRekVEEAISLVGLKPLAHRLVD--SLSGGERQRAWIAML 161
Cdd:cd03260   81 RRVGMVFQKPNPFP-GSIYDNVAYG--LRlHGIKLKEELDER--VEEALRKAALWDEVKDRLHalGLSGGQQQRLCLARA 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 536036476 162 VAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQErgLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEI 235
Cdd:cd03260  156 LANEPEVLLLDEPTSALDPISTAKIEELIAELKKE--YTIVIVTHNMQQAARVADRTAFLLNGRLVEFGPTEQI 227
ECF_ATPase_1 TIGR04520
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 14-244 1.05e-42

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275313 [Multi-domain]  Cd Length: 268  Bit Score: 146.42  E-value: 1.05e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   14 LRNISFRVPGRTL--LHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFAR-KVAYL 90
Cdd:TIGR04520   3 VENVSFSYPESEKpaLKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSGKVTVDGLDTLDEENLWEIRkKVGMV 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   91 PQ----QLPpaeGMTVRELVAigrypwhgalgrFG----AADREK----VEEAISLVGLKPLAHRLVDSLSGGERQRAWI 158
Cdd:TIGR04520  83 FQnpdnQFV---GATVEDDVA------------FGlenlGVPREEmrkrVDEALKLVGMEDFRDREPHLLSGGQKQRVAI 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  159 AMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARyCDYLVALRGGEMIAQGTPAEIM-R 237
Cdd:TIGR04520 148 AGVLAMRPDIIILDEATSMLDPKGRKEVLETIRKLNKEEGITVISITHDMEEAVL-ADRVIVMNKGKIVAEGTPREIFsQ 226


                  ....*..
gi 536036476  238 GETLEMI 244
Cdd:TIGR04520 227 VELLKEI 233
cbiO PRK13635
energy-coupling factor ABC transporter ATP-binding protein;
14-244 1.10e-42

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184195 [Multi-domain]  Cd Length: 279  Bit Score: 146.70  E-value: 1.10e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPG--RTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLP 91
Cdd:PRK13635   8 VEHISFRYPDaaTYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMVLSEETVWDVRRQVGMVF 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  92 QQlPPAE--GMTVRELVAigrypwhgalgrFGAADR--------EKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAML 161
Cdd:PRK13635  88 QN-PDNQfvGATVQDDVA------------FGLENIgvpreemvERVDQALRQVGMEDFLNREPHRLSGGQKQRVAIAGV 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 162 VAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARyCDYLVALRGGEMIAQGTPAEIMR-GET 240
Cdd:PRK13635 155 LALQPDIIILDEATSMLDPRGRREVLETVRQLKEQKGITVLSITHDLDEAAQ-ADRVIVMNKGEILEEGTPEEIFKsGHM 233


                 ....
gi 536036476 241 LEMI 244
Cdd:PRK13635 234 LQEI 237
SunT COG2274
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...
 14-236 1.36e-42

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];


Pssm-ID: 441875 [Multi-domain]  Cd Length: 711  Bit Score: 153.84  E-value: 1.36e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRT--LLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLP 91
Cdd:COG2274  476 LENVSFRYPGDSppVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGIDLRQIDPASLRRQIGVVL 555

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  92 QQLPPAEGmTVRELVAIGRypwhgalgrfGAADREKVEEAISLVGLKPLAHRLVD-----------SLSGGERQRAWIAM 160
Cdd:COG2274  556 QDVFLFSG-TIRENITLGD----------PDATDEEIIEAARLAGLHDFIEALPMgydtvvgeggsNLSGGQRQRLAIAR 624

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 536036476 161 LVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERglTVIAVLHDINMaARYCDYLVALRGGEMIAQGTPAEIM 236
Cdd:COG2274  625 ALLRNPRILILDEATSALDAETEAIILENLRRLLKGR--TVIIIAHRLST-IRLADRIIVLDKGRIVEDGTHEELL 697
ABC_drug_resistance_like cd03264
ABC-type multidrug transport system, ATPase component; The biological function of this family ...
 14-230 3.10e-42

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213231 [Multi-domain]  Cd Length: 211  Bit Score: 143.49  E-value: 3.10e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGkVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESwSSKAFARKVAYLPQQ 93
Cdd:cd03264    3 LENLTKRYGKKRALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDVLK-QPQKLRRRIGYLPQE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  94 LPPAEGMTVRELVAigrypWHGALGRFGAAD-REKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLD 172
Cdd:cd03264   81 FGVYPNFTVREFLD-----YIAWLKGIPSKEvKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSILIVD 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 536036476 173 EPTSALDIAHQVDVLSLVHRLSQERglTVIAVLHDINMAARYCDYLVALRGGEMIAQG 230
Cdd:cd03264  156 EPTAGLDPEERIRFRNLLSELGEDR--IVILSTHIVEDVESLCNQVAVLNKGKLVFEG 211
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 14-235 7.57e-42

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 146.40  E-value: 7.57e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSskAFARKVAYLPQQ 93
Cdd:COG3842    8 LENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTGLP--PEKRNVGMVFQD 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  94 L---PPaegMTVRELVAIG-RypwhgaLGRFGAADR-EKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRC 168
Cdd:COG3842   86 YalfPH---LTVAENVAFGlR------MRGVPKAEIrARVAELLELVGLEGLADRYPHQLSGGQQQRVALARALAPEPRV 156

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 536036476 169 LLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEI 235
Cdd:COG3842  157 LLLDEPLSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEI 223
CydC COG4987
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...
 8-237 1.71e-41

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444011 [Multi-domain]  Cd Length: 569  Bit Score: 149.53  E-value: 1.71e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   8 SDTTFALRNISFRVPG--RTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFAR 85
Cdd:COG4987  330 GGPSLELEDVSFRYPGagRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRDLDEDDLRR 409

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  86 KVAYLPQQlPPAEGMTVRELVAIGRypwhgalgrfGAADREKVEEAISLVGLKPLAHRLVD-----------SLSGGERQ 154
Cdd:COG4987  410 RIAVVPQR-PHLFDTTLRENLRLAR----------PDATDEELWAALERVGLGDWLAALPDgldtwlgeggrRLSGGERR 478

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 155 RAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERglTVIAVLHDINMAARyCDYLVALRGGEMIAQGTPAE 234
Cdd:COG4987  479 RLALARALLRDAPILLLDEPTEGLDAATEQALLADLLEALAGR--TVLLITHRLAGLER-MDRILVLEDGRIVEQGTHEE 555


                 ...
gi 536036476 235 IMR 237
Cdd:COG4987  556 LLA 558
ABCC_MRP_Like cd03228
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...
 14-225 2.32e-41

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213195 [Multi-domain]  Cd Length: 171  Bit Score: 139.83  E-value: 2.32e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRT--LLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLP 91
Cdd:cd03228    3 FKNVSFSYPGRPkpVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRDLDLESLRKNIAYVP 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  92 QQlPPAEGMTVRELVaigrypwhgalgrfgaadrekveeaislvglkplahrlvdsLSGGERQRAWIAMLVAQDSRCLLL 171
Cdd:cd03228   83 QD-PFLFSGTIRENI-----------------------------------------LSGGQRQRIAIARALLRDPPILIL 120

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 536036476 172 DEPTSALDIAHQVDVLSLVHRLSQERglTVIAVLHDINMaARYCDYLVALRGGE 225
Cdd:cd03228  121 DEATSALDPETEALILEALRALAKGK--TVIVIAHRLST-IRDADRIIVLDDGR 171
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
 14-230 5.08e-41

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 140.35  E-value: 5.08e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSskAFARKVAYLPQQ 93
Cdd:cd03259    3 LKGLSKTYGSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTGVP--PERRNIGMVFQD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  94 LPPAEGMTVRELVAIGrypwhGALGRFGAAD-REKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLD 172
Cdd:cd03259   81 YALFPHLTVAENIAFG-----LKLRGVPKAEiRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLLLLD 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 536036476 173 EPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQG 230
Cdd:cd03259  156 EPLSALDAKLREELREELKELQRELGITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213
ABC_DR_subfamily_A cd03230
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...
 14-226 1.08e-40

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213197 [Multi-domain]  Cd Length: 173  Bit Score: 138.30  E-value: 1.08e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESwSSKAFARKVAYLPQQ 93
Cdd:cd03230    3 VRNLSKRYGKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIKK-EPEEVKRRIGYLPEE 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  94 LPPAEGMTVRELVaigrypwhgalgrfgaadrekveeaislvglkplahrlvdSLSGGERQRAWIAMLVAQDSRCLLLDE 173
Cdd:cd03230   82 PSLYENLTVRENL----------------------------------------KLSGGMKQRLALAQALLHDPELLILDE 121

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 536036476 174 PTSALDIAHQVDVLSLVHRLSQErGLTVIAVLHDINMAARYCDYLVALRGGEM 226
Cdd:cd03230  122 PTSGLDPESRREFWELLRELKKE-GKTILLSSHILEEAERLCDRVAILNNGRI 173
ABC_Class3 cd03229
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...
 14-225 1.61e-40

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213196 [Multi-domain]  Cd Length: 178  Bit Score: 138.09  E-value: 1.61e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPL--ESWSSKAFARKVAYLP 91
Cdd:cd03229    3 LKNVSKRYGQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLtdLEDELPPLRRRIGMVF 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  92 QQ--LPPaeGMTVRELVAIGrypwhgalgrfgaadrekveeaislvglkplahrlvdsLSGGERQRAWIAMLVAQDSRCL 169
Cdd:cd03229   83 QDfaLFP--HLTVLENIALG--------------------------------------LSGGQQQRVALARALAMDPDVL 122

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 536036476 170 LLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGE 225
Cdd:cd03229  123 LLDEPTSALDPITRREVRALLKSLQAQLGITVVLVTHDLDEAARLADRVVVLRDGK 178
ABC_NrtD_SsuB_transporters cd03293
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...
 14-223 2.58e-39

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213260 [Multi-domain]  Cd Length: 220  Bit Score: 136.06  E-value: 2.58e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGR----TLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSskafaRKVAY 89
Cdd:cd03293    3 VRNVSKTYGGGggavTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEPVTGPG-----PDRGY 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  90 LPQQ---LPpaeGMTVRELVAIGRypwhGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDS 166
Cdd:cd03293   78 VFQQdalLP---WLTVLDNVALGL----ELQGVPKAEARERAEELLELVGLSGFENAYPHQLSGGMRQRVALARALAVDP 150

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 536036476 167 RCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRG 223
Cdd:cd03293  151 DVLLLDEPFSALDALTREQLQEELLDIWRETGKTVLLVTHDIDEAVFLADRVVVLSA 207
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
14-245 1.01e-38

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 140.92  E-value: 1.01e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSK-AFARKVAYLPQ 92
Cdd:COG1129    7 MRGISKSFGGVKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPVRFRSPRdAQAAGIAIIHQ 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  93 QLPPAEGMTVRELVAIGRYPwhgalGRFGAAD----REKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRC 168
Cdd:COG1129   87 ELNLVPNLSVAENIFLGREP-----RRGGLIDwramRRRARELLARLGLDIDPDTPVGDLSVAQQQLVEIARALSRDARV 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 169 LLLDEPTSALDiAHQVDVL-SLVHRLsQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEI--------MRGE 239
Cdd:COG1129  162 LILDEPTASLT-EREVERLfRIIRRL-KAQGVAIIYISHRLDEVFEIADRVTVLRDGRLVGTGPVAELtedelvrlMVGR 239


                 ....*.
gi 536036476 240 TLEMIY 245
Cdd:COG1129  240 ELEDLF 245
TauB COG1116
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...
 6-224 1.65e-38

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440733 [Multi-domain]  Cd Length: 260  Bit Score: 135.22  E-value: 1.65e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   6 NHSDTTFALRNIS--FRVPG--RTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLEswssk 81
Cdd:COG1116    2 SAAAPALELRGVSkrFPTGGggVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGKPVT----- 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  82 AFARKVAYLPQQ--LPPAegMTVRELVAIGRypwhGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIA 159
Cdd:COG1116   77 GPGPDRGVVFQEpaLLPW--LTVLDNVALGL----ELRGVPKAERRERARELLELVGLAGFEDAYPHQLSGGMRQRVAIA 150

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 536036476 160 MLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGG 224
Cdd:COG1116  151 RALANDPEVLLMDEPFGALDALTRERLQDELLRLWQETGKTVLFVTHDVDEAVFLADRVVVLSAR 215
ABC_MetN_methionine_transporter cd03258
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...
 3-235 1.68e-38

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213225 [Multi-domain]  Cd Length: 233  Bit Score: 134.63  E-value: 1.68e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   3 EYTNHSDTTFALRNISfrvpgrtllhplsLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKA 82
Cdd:cd03258   10 VFGDTGGKVTALKDVS-------------LSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLLSGKE 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  83 ---FARKVAYLPQQLPPAEGMTVRELVAigrYPWHGAlGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIA 159
Cdd:cd03258   77 lrkARRRIGMIFQHFNLLSSRTVFENVA---LPLEIA-GVPKAEIEERVLELLELVGLEDKADAYPAQLSGGQKQRVGIA 152

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 536036476 160 MLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEI 235
Cdd:cd03258  153 RALANNPKVLLCDEATSALDPETTQSILALLRDINRELGLTIVLITHEMEVVKRICDRVAVMEKGEVVEEGTVEEV 228
MdlB COG1132
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
14-237 2.42e-38

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];


Pssm-ID: 440747 [Multi-domain]  Cd Length: 579  Bit Score: 141.07  E-value: 2.42e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFR-VPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQ 92
Cdd:COG1132  342 FENVSFSyPGDRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGVDIRDLTLESLRRQIGVVPQ 421

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  93 qlppaEG----MTVRELVAIGRypwhgalgrfGAADREKVEEAISLVGLKPLAHRLVD-----------SLSGGERQRAW 157
Cdd:COG1132  422 -----DTflfsGTIRENIRYGR----------PDATDEEVEEAAKAAQAHEFIEALPDgydtvvgergvNLSGGQRQRIA 486

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 158 IAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERglTVIAVLHDINmAARYCDYLVALRGGEMIAQGTPAEIMR 237
Cdd:COG1132  487 IARALLKDPPILILDEATSALDTETEALIQEALERLMKGR--TTIVIAHRLS-TIRNADRILVLDDGRIVEQGTHEELLA 563
CydD TIGR02857
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...
 8-221 1.47e-37

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD


Pssm-ID: 274323 [Multi-domain]  Cd Length: 529  Bit Score: 138.19  E-value: 1.47e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476    8 SDTTFALRNISFRVPGRT-LLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARK 86
Cdd:TIGR02857 318 PASSLEFSGVSVAYPGRRpALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLADADADSWRDQ 397

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   87 VAYLPQQ--LPPAegmTVRELVAIGRypwhgalgrfGAADREKVEEAISLVGLKPLA-------HRLVDS----LSGGER 153
Cdd:TIGR02857 398 IAWVPQHpfLFAG---TIAENIRLAR----------PDASDAEIREALERAGLDEFVaalpqglDTPIGEggagLSGGQA 464

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 536036476  154 QRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERglTVIAVLHDINMAARyCDYLVAL 221
Cdd:TIGR02857 465 QRLALARAFLRDAPLLLLDEPTAHLDAETEAEVLEALRALAQGR--TVLLVTHRLALAAL-ADRIVVL 529
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
 30-235 2.78e-37

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 131.09  E-value: 2.78e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  30 LSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFaRKVAYLPQQLPPAEGMTVRELVAIg 109
Cdd:cd03263   21 LSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSIRTDRKAAR-QSLGYCPQFDALFDELTVREHLRF- 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 110 rypwHGAL-GRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLS 188
Cdd:cd03263   99 ----YARLkGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVLLLDEPTSGLDPASRRAIWD 174

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 536036476 189 LVHRLSQERglTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEI 235
Cdd:cd03263  175 LILEVRKGR--SIILTTHSMDEAEALCDRIAIMSDGKLRCIGSPQEL 219
ABC_TM1139_LivF_branched cd03224
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...
 27-236 1.29e-36

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.


Pssm-ID: 213191 [Multi-domain]  Cd Length: 222  Bit Score: 129.09  E-value: 1.29e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  27 LHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARK-VAYLPQ--QLPPaeGMTVR 103
Cdd:cd03224   16 LFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDITGLPPHERARAgIGYVPEgrRIFP--ELTVE 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 104 ELVAIGRYPwhgalgRFGAADREKVEEAISLV-GLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSAL--DI 180
Cdd:cd03224   94 ENLLLGAYA------RRRAKRKARLERVYELFpRLKERRKQLAGTLSGGEQQMLAIARALMSRPKLLLLDEPSEGLapKI 167

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 536036476 181 AHQvdVLSLVHRLSQErGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIM 236
Cdd:cd03224  168 VEE--IFEAIRELRDE-GVTILLVEQNARFALEIADRAYVLERGRVVLEGTAAELL 220
ModC COG4148
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ...
 31-237 1.64e-36

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443319 [Multi-domain]  Cd Length: 358  Bit Score: 132.53  E-value: 1.64e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  31 SLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAF----ARKVAYLPQQ--LPPAegMTVRE 104
Cdd:COG4148   19 DFTLPGRGVTALFGPSGSGKTTLLRAIAGLERPDSGRIRLGGEVLQDSARGIFlpphRRRIGYVFQEarLFPH--LSVRG 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 105 LVAIGRypWHGAlgrfGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQV 184
Cdd:COG4148   97 NLLYGR--KRAP----RAERRISFDEVVELLGIGHLLDRRPATLSGGERQRVAIGRALLSSPRLLLMDEPLAALDLARKA 170

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 536036476 185 DVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMR 237
Cdd:COG4148  171 EILPYLERLRDELDIPILYVSHSLDEVARLADHVVLLEQGRVVASGPLAEVLS 223
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
 14-235 2.30e-35

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 126.20  E-value: 2.30e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLeswsskafarkvaylpQQ 93
Cdd:cd03300    3 LENVSKFYGGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDI----------------TN 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  94 LPPAE--------------GMTVRELVAIGRypwhgALGRFGAAD-REKVEEAISLVGLKPLAHRLVDSLSGGERQRAWI 158
Cdd:cd03300   67 LPPHKrpvntvfqnyalfpHLTVFENIAFGL-----RLKKLPKAEiKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAI 141

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 536036476 159 AMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEI 235
Cdd:cd03300  142 ARALVNEPKVLLLDEPLGALDLKLRKDMQLELKRLQKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGTPEEI 218
ABC_cobalt_CbiO_domain2 cd03226
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...
 16-225 2.51e-35

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213193 [Multi-domain]  Cd Length: 205  Bit Score: 125.45  E-value: 2.51e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  16 NISFRVP-GRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLeswSSKAFARKVAYLPQ-- 92
Cdd:cd03226    4 NISFSYKkGTEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKPI---KAKERRKSIGYVMQdv 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  93 --QLppaEGMTVRELVAIGRypwhgalgRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLL 170
Cdd:cd03226   81 dyQL---FTDSVREELLLGL--------KELDAGNEQAETVLKDLDLYALKERHPLSLSGGQKQRLAIAAALLSGKDLLI 149

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 536036476 171 LDEPTSALDIAHQVDVLSLVHRLsQERGLTVIAVLHDINMAARYCDYLVALRGGE 225
Cdd:cd03226  150 FDEPTSGLDYKNMERVGELIREL-AAQGKAVIVITHDYEFLAKVCDRVLLLANGA 203
DppD COG0444
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 16-237 3.90e-35

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440213 [Multi-domain]  Cd Length: 320  Bit Score: 127.86  E-value: 3.90e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  16 NISFRVPGRTL--LHPLSLTFPAGKVTGLIGHNGSGKSTLLKM-LGRHQPP--SEGEILLDAQPLESWSSKAF----ARK 86
Cdd:COG0444    8 KVYFPTRRGVVkaVDGVSFDVRRGETLGLVGESGSGKSTLARAiLGLLPPPgiTSGEILFDGEDLLKLSEKELrkirGRE 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  87 VAYLPQQ----LPPAegMTVRELVAIG-RYpwHGALGRfgAADREKVEEAISLVGLkPLAHRLVDS----LSGGERQRAW 157
Cdd:COG0444   88 IQMIFQDpmtsLNPV--MTVGDQIAEPlRI--HGGLSK--AEARERAIELLERVGL-PDPERRLDRypheLSGGMRQRVM 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 158 IAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMR 237
Cdd:COG0444  161 IARALALEPKLLIADEPTTALDVTIQAQILNLLKDLQRELGLAILFITHDLGVVAEIADRVAVMYAGRIVEEGPVEELFE 240
ABC_ThiQ_thiamine_transporter cd03298
ATP-binding cassette domain of the thiamine transport system; Part of the ...
 13-230 4.41e-35

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213265 [Multi-domain]  Cd Length: 211  Bit Score: 124.91  E-value: 4.41e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  13 ALRNISFRVpGRTLLHpLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESwsSKAFARKVAYLPQ 92
Cdd:cd03298    2 RLDKIRFSY-GEQPMH-FDLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVDVTA--APPADRPVSMLFQ 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  93 QLPPAEGMTVRELVAIGRYPwhgALgRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLD 172
Cdd:cd03298   78 ENNLFAHLTVEQNVGLGLSP---GL-KLTAEDRQAIEVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLD 153

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 536036476 173 EPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQG 230
Cdd:cd03298  154 EPFAALDPALRAEMLDLVLDLHAETKMTVLMVTHQPEDAKRLAQRVVFLDNGRIAAQG 211
FtsE COG2884
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
14-234 1.40e-34

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442130 [Multi-domain]  Cd Length: 223  Bit Score: 124.01  E-value: 1.40e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVP-GRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLeswsSKAFARKVAYLPQ 92
Cdd:COG2884    4 FENVSKRYPgGREALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDL----SRLKRREIPYLRR 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  93 QLppaeGM-----------TVRELVAIgrypwhgAL---GRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWI 158
Cdd:COG2884   80 RI----GVvfqdfrllpdrTVYENVAL-------PLrvtGKSRKEIRRRVREVLDLVGLSDKAKALPHELSGGEQQRVAI 148

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 536036476 159 AMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQeRGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAE 234
Cdd:COG2884  149 ARALVNRPELLLADEPTGNLDPETSWEIMELLEEINR-RGTTVLIATHDLELVDRMPKRVLELEDGRLVRDEARGV 223
PRK15056 PRK15056
manganese/iron ABC transporter ATP-binding protein;
8-256 1.53e-34

manganese/iron ABC transporter ATP-binding protein;


Pssm-ID: 185016 [Multi-domain]  Cd Length: 272  Bit Score: 125.38  E-value: 1.53e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   8 SDTTFALRNisfrvpGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLEswssKAFARK- 86
Cdd:PRK15056  10 NDVTVTWRN------GHTALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQPTR----QALQKNl 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  87 VAYLPQ--QLPPAEGMTVRELVAIGRYPWHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQ 164
Cdd:PRK15056  80 VAYVPQseEVDWSFPVLVEDVVMMGRYGHMGWLRRAKKRDRQIVTAALARVDMVEFRHRQIGELSGGQKKRVFLARAIAQ 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 165 DSRCLLLDEPTSALDIAHQVDVLSLVHRLSQErGLTVIAVLHDINMAARYCDYLVALRgGEMIAQGTPAEIMRGETLEMI 244
Cdd:PRK15056 160 QGQVILLDEPFTGVDVKTEARIISLLRELRDE-GKTMLVSTHNLGSVTEFCDYTVMVK-GTVLASGPTETTFTAENLELA 237

                        250
                 ....*....|..
gi 536036476 245 YGipmGILPHPA 256
Cdd:PRK15056 238 FS---GVLRHVA 246
cbiO PRK13648
cobalt transporter ATP-binding subunit; Provisional
 8-244 2.91e-34

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184207 [Multi-domain]  Cd Length: 269  Bit Score: 124.48  E-value: 2.91e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   8 SDTTFALRNISFRVPgrtllhplsltfpAGKVTGLIGHNGSGKSTLLK-MLGRHQpPSEGEILLDAQPLESWSSKAFARK 86
Cdd:PRK13648  19 SDASFTLKDVSFNIP-------------KGQWTSIVGHNGSGKSTIAKlMIGIEK-VKSGEIFYNNQAITDDNFEKLRKH 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  87 VAYLPQQlPPAE--GMTVRELVAIGrypwhgaLGRFGAAD---REKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAML 161
Cdd:PRK13648  85 IGIVFQN-PDNQfvGSIVKYDVAFG-------LENHAVPYdemHRRVSEALKQVDMLERADYEPNALSGGQKQRVAIAGV 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 162 VAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARyCDYLVALRGGEMIAQGTPAEIMR-GET 240
Cdd:PRK13648 157 LALNPSVIILDEATSMLDPDARQNLLDLVRKVKSEHNITIISITHDLSEAME-ADHVIVMNKGTVYKEGTPTEIFDhAEE 235


                 ....
gi 536036476 241 LEMI 244
Cdd:PRK13648 236 LTRI 239
ArpD COG4618
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ...
 14-237 1.01e-33

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443660 [Multi-domain]  Cd Length: 563  Bit Score: 127.94  E-value: 1.01e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPG--RTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLP 91
Cdd:COG4618  333 VENLTVVPPGskRPILRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGADLSQWDREELGRHIGYLP 412

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  92 Q--QLPPAegmTVRELVAigrypwhgalgRFGAADREKVEEAISLVGlkplAHRLVDS---------------LSGGERQ 154
Cdd:COG4618  413 QdvELFDG---TIAENIA-----------RFGDADPEKVVAAAKLAG----VHEMILRlpdgydtrigeggarLSGGQRQ 474

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 155 RAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLsQERGLTVIAVLHDINmAARYCDYLVALRGGEMIAQGTPAE 234
Cdd:COG4618  475 RIGLARALYGDPRLVVLDEPNSNLDDEGEAALAAAIRAL-KARGATVVVITHRPS-LLAAVDKLLVLRDGRVQAFGPRDE 552


                 ...
gi 536036476 235 IMR 237
Cdd:COG4618  553 VLA 555
ABC_CysA_sulfate_importer cd03296
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...
 15-246 1.51e-33

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213263 [Multi-domain]  Cd Length: 239  Bit Score: 121.68  E-value: 1.51e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  15 RNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQplESWSSKAFARKVAYLPQQL 94
Cdd:cd03296    6 RNVSKRFGDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGE--DATDVPVQERNVGFVFQHY 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  95 PPAEGMTVRELVAIGRYPWHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEP 174
Cdd:cd03296   84 ALFRHMTVFDNVAFGLRVKPRSERPPEAEIRAKVHELLKLVQLDWLADRYPAQLSGGQRQRVALARALAVEPKVLLLDEP 163

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 536036476 175 TSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMRGETLEMIYG 246
Cdd:cd03296  164 FGALDAKVRKELRRWLRRLHDELHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGTPDEVYDHPASPFVYS 235
ABC_Pro_Gly_Betaine cd03294
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...
 8-237 1.90e-33

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213261 [Multi-domain]  Cd Length: 269  Bit Score: 122.37  E-value: 1.90e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   8 SDTTFALRNISFRVPgrtllhplsltfpAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFaRKV 87
Cdd:cd03294   34 TGQTVGVNDVSLDVR-------------EGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIAAMSRKEL-REL 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  88 ------------AYLPQqlppaegMTVRELVAIGrypwhgaL---GRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGE 152
Cdd:cd03294  100 rrkkismvfqsfALLPH-------RTVLENVAFG-------LevqGVPRAEREERAAEALELVGLEGWEHKYPDELSGGM 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 153 RQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTP 232
Cdd:cd03294  166 QQRVGLARALAVDPDILLMDEAFSALDPLIRREMQDELLRLQAELQKTIVFITHDLDEALRLGDRIAIMKDGRLVQVGTP 245


                 ....*
gi 536036476 233 AEIMR 237
Cdd:cd03294  246 EEILT 250
ABC_YhbG cd03218
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...
 14-245 2.22e-33

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.


Pssm-ID: 213185 [Multi-domain]  Cd Length: 232  Bit Score: 121.11  E-value: 2.22e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARK-VAYLPQ 92
Cdd:cd03218    3 AENLSKRYGKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKLPMHKRARLgIGYLPQ 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  93 QLPPAEGMTVRE-LVAIGRYpwhgaLGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLL 171
Cdd:cd03218   83 EASIFRKLTVEEnILAVLEI-----RGLSKKEREEKLEELLEEFHITHLRKSKASSLSGGERRRVEIARALATNPKFLLL 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 536036476 172 DEPTSALD-IAHQvDVLSLVHRLSqERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMRGETLEMIY 245
Cdd:cd03218  158 DEPFAGVDpIAVQ-DIQKIIKILK-DRGIGVLITDHNVRETLSITDRAYIIYEGKVLAEGTPEEIAANELVRKVY 230
modC_ABC TIGR02142
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ...
 30-237 5.04e-33

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]


Pssm-ID: 131197 [Multi-domain]  Cd Length: 354  Bit Score: 123.30  E-value: 5.04e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   30 LSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAF----ARKVAYLPQQLPPAEGMTVREL 105
Cdd:TIGR02142  16 ADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPDEGEIVLNGRTLFDSRKGIFlppeKRRIGYVFQEARLFPHLSVRGN 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  106 VAIGRYpwhgalgRFGAADREKVEEAI-SLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQV 184
Cdd:TIGR02142  96 LRYGMK-------RARPSERRISFERViELLGIGHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLAALDDPRKY 168

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 536036476  185 DVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMR 237
Cdd:TIGR02142 169 EILPYLERLHAEFGIPILYVSHSLQEVLRLADRVVVLEDGRVAAAGPIAEVWA 221
ABC_MTABC3_MDL1_MDL2 cd03249
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...
 14-236 7.95e-33

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.


Pssm-ID: 213216 [Multi-domain]  Cd Length: 238  Bit Score: 119.95  E-value: 7.95e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGR---TLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYL 90
Cdd:cd03249    3 FKNVSFRYPSRpdvPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDIRDLNLRWLRSQIGLV 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  91 PQQlPPAEGMTVRELVAIGRYPwhgalgrfgaADREKVEEAISLVGlkplAHRLVDS---------------LSGGERQR 155
Cdd:cd03249   83 SQE-PVLFDGTIAENIRYGKPD----------ATDEEVEEAAKKAN----IHDFIMSlpdgydtlvgergsqLSGGQKQR 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 156 AWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERglTVIAVLHDINmAARYCDYLVALRGGEMIAQGTPAEI 235
Cdd:cd03249  148 IAIARALLRNPKILLLDEATSALDAESEKLVQEALDRAMKGR--TTIVIAHRLS-TIRNADLIAVLQNGQVVEQGTHDEL 224


                 .
gi 536036476 236 M 236
Cdd:cd03249  225 M 225
YhaQ COG4152
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 13-263 1.09e-32

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443322 [Multi-domain]  Cd Length: 298  Bit Score: 120.98  E-value: 1.09e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  13 ALRNISFRVPgrtllhplsltfpAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLeswsSKAFARKVAYLPQ 92
Cdd:COG4152   16 AVDDVSFTVP-------------KGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPL----DPEDRRRIGYLPE 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  93 Q--LPPAegMTVRE-LVAIGRYpwHGaLGRfgAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCL 169
Cdd:COG4152   79 ErgLYPK--MKVGEqLVYLARL--KG-LSK--AEAKRRADEWLERLGLGDRANKKVEELSKGNQQKVQLIAALLHDPELL 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 170 LLDEPTSALD-IAhqVDVLS-LVHRLsQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEI---MRGETLEMI 244
Cdd:COG4152  152 ILDEPFSGLDpVN--VELLKdVIREL-AAKGTTVIFSSHQMELVEELCDRIVIINKGRKVLSGSVDEIrrqFGRNTLRLE 228

                        250
                 ....*....|....*....
gi 536036476 245 YGIPMGILPHPAGAAPVSF 263
Cdd:COG4152  229 ADGDAGWLRALPGVTVVEE 247
MalK COG3839
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...
 14-235 2.60e-32

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];


Pssm-ID: 443050 [Multi-domain]  Cd Length: 352  Bit Score: 121.33  E-value: 2.60e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKML-GRHqPPSEGEILLDAQPLESWSSKafARKVAYLPQ 92
Cdd:COG3839    6 LENVSKSYGGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIaGLE-DPTSGEILIGGRDVTDLPPK--DRNIAMVFQ 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  93 Q--LPPAegMTVRELVAIG-RypwhgaLGRFGAADR-EKVEEAISLVGLKPLAHRLVDSLSGGERQRawIAM---LVAqD 165
Cdd:COG3839   83 SyaLYPH--MTVYENIAFPlK------LRKVPKAEIdRRVREAAELLGLEDLLDRKPKQLSGGQRQR--VALgraLVR-E 151

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 536036476 166 SRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHD----INMAarycDYLVALRGGEMIAQGTPAEI 235
Cdd:COG3839  152 PKVFLLDEPLSNLDAKLRVEMRAEIKRLHRRLGTTTIYVTHDqveaMTLA----DRIAVMNDGRIQQVGTPEEL 221
PRK09984 PRK09984
phosphonate ABC transporter ATP-binding protein;
27-231 3.64e-32

phosphonate ABC transporter ATP-binding protein;


Pssm-ID: 182182 [Multi-domain]  Cd Length: 262  Bit Score: 118.96  E-value: 3.64e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  27 LHPLSLTFPAGKVTGLIGHNGSGKSTLLKML-----GRHQPPSEGEILLDAQPLESWSSKAFARKVA---YLPQQLPPAE 98
Cdd:PRK09984  20 LHAVDLNIHHGEMVALLGPSGSGKSTLLRHLsglitGDKSAGSHIELLGRTVQREGRLARDIRKSRAntgYIFQQFNLVN 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  99 GMTVRELV---AIGRYP-WHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEP 174
Cdd:PRK09984 100 RLSVLENVligALGSTPfWRTCFSWFTREQKQRALQALTRVGMVHFAHQRVSTLSGGQQQRVAIARALMQQAKVILADEP 179

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 536036476 175 TSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGT 231
Cdd:PRK09984 180 IASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALRYCERIVALRQGHVFYDGS 236
ABC_DrrA cd03265
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...
 9-235 3.65e-32

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213232 [Multi-domain]  Cd Length: 220  Bit Score: 117.47  E-value: 3.65e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   9 DTTFALRNISFRVPgrtllhplsltfpAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESwSSKAFARKVA 88
Cdd:cd03265   11 GDFEAVRGVSFRVR-------------RGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDVVR-EPREVRRRIG 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  89 YLPQQLPPAEGMTVRELVAigrypWHGAL-GRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSR 167
Cdd:cd03265   77 IVFQDLSVDDELTGWENLY-----IHARLyGVPGAERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPE 151

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 536036476 168 CLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEI 235
Cdd:cd03265  152 VLFLDEPTIGLDPQTRAHVWEYIEKLKEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTPEEL 219
AbcC COG1135
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
14-235 4.04e-32

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440750 [Multi-domain]  Cd Length: 339  Bit Score: 120.57  E-value: 4.04e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNIS--FRVPGRTL--LHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSK---AFARK 86
Cdd:COG1135    4 LENLSktFPTKGGPVtaLDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVDLTALSERelrAARRK 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  87 VaylpqqlppaeGM-----------TVRELVAigrYPwhgaL---GRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGE 152
Cdd:COG1135   84 I-----------GMifqhfnllssrTVAENVA---LP----LeiaGVPKAEIRKRVAELLELVGLSDKADAYPSQLSGGQ 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 153 RQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTP 232
Cdd:COG1135  146 KQRVGIARALANNPKVLLCDEATSALDPETTRSILDLLKDINRELGLTIVLITHEMDVVRRICDRVAVLENGRIVEQGPV 225


                 ...
gi 536036476 233 AEI 235
Cdd:COG1135  226 LDV 228
LivF COG0410
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...
 27-241 5.76e-32

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];


Pssm-ID: 440179 [Multi-domain]  Cd Length: 236  Bit Score: 117.39  E-value: 5.76e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  27 LHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARK-VAYLPQ--QLPPaeGMTVR 103
Cdd:COG0410   19 LHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGEDITGLPPHRIARLgIGYVPEgrRIFP--SLTVE 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 104 E-LVaigrypwhgaLGRFGAADREKVEEAISLVG-----LKPLAHRLVDSLSGGERQ-----RAwiamLVAqDSRCLLLD 172
Cdd:COG0410   97 EnLL----------LGAYARRDRAEVRADLERVYelfprLKERRRQRAGTLSGGEQQmlaigRA----LMS-RPKLLLLD 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 536036476 173 EPTsaLDIAHQV--DVLSLVHRLsQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMRGETL 241
Cdd:COG0410  162 EPS--LGLAPLIveEIFEIIRRL-NREGVTILLVEQNARFALEIADRAYVLERGRIVLEGTAAELLADPEV 229
ABC_Carb_Monos_I cd03216
First domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 12-229 9.19e-32

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213183 [Multi-domain]  Cd Length: 163  Bit Score: 114.83  E-value: 9.19e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  12 FALRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSK-AFARKVAYL 90
Cdd:cd03216    1 LELRGITKRFGGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEVSFASPRdARRAGIAMV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  91 PQqlppaegmtvrelvaigrypwhgalgrfgaadrekveeaislvglkplahrlvdsLSGGERQRAWIAMLVAQDSRCLL 170
Cdd:cd03216   81 YQ-------------------------------------------------------LSVGERQMVEIARALARNARLLI 105

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 536036476 171 LDEPTSALDIAHQVDVLSLVHRLsQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQ 229
Cdd:cd03216  106 LDEPTAALTPAEVERLFKVIRRL-RAQGVAVIFISHRLDEVFEIADRVTVLRDGRVVGT 163
cbiO PRK13632
cobalt transporter ATP-binding subunit; Provisional
 5-239 9.59e-32

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237452 [Multi-domain]  Cd Length: 271  Bit Score: 117.78  E-value: 9.59e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   5 TNHSDTTFALRNISFRVPG--RTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLeSWSSKA 82
Cdd:PRK13632   1 IKNKSVMIKVENVSFSYPNseNNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITI-SKENLK 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  83 FARKVAYLPQQLPPAE--GMTVRELVAIG----RYPwhgalgrfgaadREK----VEEAISLVGLKPLAHRLVDSLSGGE 152
Cdd:PRK13632  80 EIRKKIGIIFQNPDNQfiGATVEDDIAFGlenkKVP------------PKKmkdiIDDLAKKVGMEDYLDKEPQNLSGGQ 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 153 RQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARyCDYLVALRGGEMIAQGTP 232
Cdd:PRK13632 148 KQRVAIASVLALNPEIIIFDESTSMLDPKGKREIKKIMVDLRKTRKKTLISITHDMDEAIL-ADKVIVFSEGKLIAQGKP 226


                 ....*..
gi 536036476 233 AEIMRGE 239
Cdd:PRK13632 227 KEILNNK 233
cbiO PRK13636
cobalt transporter ATP-binding subunit; Provisional
 9-247 1.45e-31

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184196 [Multi-domain]  Cd Length: 283  Bit Score: 117.64  E-value: 1.45e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   9 DTTFALRNISFRVP-GRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLEsWSSKAFA--R 85
Cdd:PRK13636   3 DYILKVEELNYNYSdGTHALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKPID-YSRKGLMklR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  86 KVAYLPQQLPPAE--GMTVRELVAIGRYpwhgALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVA 163
Cdd:PRK13636  82 ESVGMVFQDPDNQlfSASVYQDVSFGAV----NLKLPEDEVRKRVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIAGVLV 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 164 QDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMRGEtlEM 243
Cdd:PRK13636 158 MEPKVLVLDEPTAGLDPMGVSEIMKLLVEMQKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGNPKEVFAEK--EM 235


                 ....
gi 536036476 244 IYGI 247
Cdd:PRK13636 236 LRKV 239
ABC_ModC_molybdenum_transporter cd03297
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...
 17-230 1.53e-31

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213264 [Multi-domain]  Cd Length: 214  Bit Score: 115.86  E-value: 1.53e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  17 ISFRVPGRTLlhPLSLTFPAGkVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAF----ARKVAYLPQ 92
Cdd:cd03297    6 IEKRLPDFTL--KIDFDLNEE-VTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTVLFDSRKKINlppqQRKIGLVFQ 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  93 QLPPAEGMTVRELVAigrypwHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLD 172
Cdd:cd03297   83 QYALFPHLNVRENLA------FGLKRKRNREDRISVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLD 156

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 536036476 173 EPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQG 230
Cdd:cd03297  157 EPFSALDRALRLQLLPELKQIKKNLNIPVIFVTHDLSEAEYLADRIVVMEDGRLQYIG 214
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 14-207 1.56e-31

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 121.71  E-value: 1.56e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQpleswsskafaRKVAYLPQQ 93
Cdd:COG0488    1 LENLSKSFGGRPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSIPKG-----------LRIGYLPQE 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  94 LPPAEGMTVRELVAIGRYPWHGAL------------------------GRFGAAD----REKVEEAISLVGLKPLAH-RL 144
Cdd:COG0488   70 PPLDDDLTVLDTVLDGDAELRALEaeleeleaklaepdedlerlaelqEEFEALGgweaEARAEEILSGLGFPEEDLdRP 149

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 536036476 145 VDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAhqvDVLSLVHRLSQERGlTVIAVLHD 207
Cdd:COG0488  150 VSELSGGWRRRVALARALLSEPDLLLLDEPTNHLDLE---SIEWLEEFLKNYPG-TVLVVSHD 208
GlnQ COG1126
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ...
 27-235 1.68e-31

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440743 [Multi-domain]  Cd Length: 239  Bit Score: 116.25  E-value: 1.68e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  27 LHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLeSWSSKAFA---RKVAYLPQQ--LPPAegMT 101
Cdd:COG1126   17 LKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDL-TDSKKDINklrRKVGMVFQQfnLFPH--LT 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 102 VRELVAIGryPWHgALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALD-- 179
Cdd:COG1126   94 VLENVTLA--PIK-VKKMSKAEAEERAMELLERVGLADKADAYPAQLSGGQQQRVAIARALAMEPKVMLFDEPTSALDpe 170

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 536036476 180 -IAhqvDVLSLVHRLSQErGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEI 235
Cdd:COG1126  171 lVG---EVLDVMRDLAKE-GMTMVVVTHEMGFAREVADRVVFMDGGRIVEEGPPEEF 223
cbiO PRK13634
cobalt transporter ATP-binding subunit; Provisional
 24-251 2.13e-31

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237454 [Multi-domain]  Cd Length: 290  Bit Score: 117.43  E-value: 2.13e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  24 RTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSS----KAFARKVAYLPQ----QLP 95
Cdd:PRK13634  20 RRALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIGERVITAGKKnkklKPLRKKVGIVFQfpehQLF 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  96 PAegmTVRELVAIGryPWHgalgrFGAADRE---KVEEAISLVGLKP-LAHRLVDSLSGGERQRAWIAMLVAQDSRCLLL 171
Cdd:PRK13634 100 EE---TVEKDICFG--PMN-----FGVSEEDakqKAREMIELVGLPEeLLARSPFELSGGQMRRVAIAGVLAMEPEVLVL 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 172 DEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMR-GETLEMI-YGIPM 249
Cdd:PRK13634 170 DEPTAGLDPKGRKEMMEMFYKLHKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREIFAdPDELEAIgLDLPE 249


                 ..
gi 536036476 250 GI 251
Cdd:PRK13634 250 TV 251
metN PRK11153
DL-methionine transporter ATP-binding subunit; Provisional
 14-235 2.73e-31

DL-methionine transporter ATP-binding subunit; Provisional


Pssm-ID: 236863 [Multi-domain]  Cd Length: 343  Bit Score: 118.36  E-value: 2.73e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNIS--FRVPGRTL--LHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSK---AFARK 86
Cdd:PRK11153   4 LKNISkvFPQGGRTIhaLNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLTALSEKelrKARRQ 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  87 VAYLPQQLPPAEGMTVRELVAIgrypwhgAL---GRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVA 163
Cdd:PRK11153  84 IGMIFQHFNLLSSRTVFDNVAL-------PLelaGTPKAEIKARVTELLELVGLSDKADRYPAQLSGGQKQRVAIARALA 156

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 536036476 164 QDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEI 235
Cdd:PRK11153 157 SNPKVLLCDEATSALDPATTRSILELLKDINRELGLTIVLITHEMDVVKRICDRVAVIDAGRLVEQGTVSEV 228
OpuBA COG1125
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ...
 14-237 4.31e-31

ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440742 [Multi-domain]  Cd Length: 306  Bit Score: 117.11  E-value: 4.31e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTL-LHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQ 92
Cdd:COG1125    4 FENVTKRYPDGTVaVDDLSLTIPAGEFTVLVGPSGCGKTTTLRMINRLIEPTSGRILIDGEDIRDLDPVELRRRIGYVIQ 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  93 Q---LPpaeGMTVRELVAIgrYPwhGALGRFGAADREKVEEAISLVGLKP--LAHRLVDSLSGGERQRAWIAMLVAQDSR 167
Cdd:COG1125   84 QiglFP---HMTVAENIAT--VP--RLLGWDKERIRARVDELLELVGLDPeeYRDRYPHELSGGQQQRVGVARALAADPP 156

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 536036476 168 CLLLDEPTSALD-IAH---QVDVLslvhRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMR 237
Cdd:COG1125  157 ILLMDEPFGALDpITReqlQDELL----RLQRELGKTIVFVTHDIDEALKLGDRIAVMREGRIVQYDTPEEILA 226
ABCG_White cd03234
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...
 24-230 6.24e-31

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.


Pssm-ID: 213201 [Multi-domain]  Cd Length: 226  Bit Score: 114.68  E-value: 6.24e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  24 RTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKML-GRHQPPS--EGEILLDAQPLeswSSKAFARKVAYLPQQLPPAEGM 100
Cdd:cd03234   20 ARILNDVSLHVESGQVMAILGSSGSGKTTLLDAIsGRVEGGGttSGQILFNGQPR---KPDQFQKCVAYVRQDDILLPGL 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 101 TVRELVaigRYPWHGALGR-FGAADREKVEE--AISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSA 177
Cdd:cd03234   97 TVRETL---TYTAILRLPRkSSDAIRKKRVEdvLLRDLALTRIGGNLVKGISGGERRRVSIAVQLLWDPKVLILDEPTSG 173

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 536036476 178 LD--IAHQvdvlsLVHRLSQ--ERGLTVIAVLH----DInmaARYCDYLVALRGGEMIAQG 230
Cdd:cd03234  174 LDsfTALN-----LVSTLSQlaRRNRIVILTIHqprsDL---FRLFDRILLLSSGEIVYSG 226
PstB COG1117
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 1-235 1.01e-30

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440734 [Multi-domain]  Cd Length: 258  Bit Score: 114.75  E-value: 1.01e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   1 MQEYTNHSDTTFALRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGR---HQPPS--EGEILLDAQPL 75
Cdd:COG1117    1 MTAPASTLEPKIEVRNLNVYYGDKQALKDINLDIPENKVTALIGPSGCGKSTLLRCLNRmndLIPGArvEGEILLDGEDI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  76 ESWSSKAFA--RKVAYLPQQ---LPpaegMTVRELVAIG-RYpwHGALGRfGAADrEKVEEAISLVGL-KPLAHRLVDS- 147
Cdd:COG1117   81 YDPDVDVVElrRRVGMVFQKpnpFP----KSIYDNVAYGlRL--HGIKSK-SELD-EIVEESLRKAALwDEVKDRLKKSa 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 148 --LSGGERQRAWIAMLVAQDSRCLLLDEPTSALD-IAHQVdVLSLVHRLSQErgLTVIAVLHdiNM--AARYCDYLVALR 222
Cdd:COG1117  153 lgLSGGQQQRLCIARALAVEPEVLLMDEPTSALDpISTAK-IEELILELKKD--YTIVIVTH--NMqqAARVSDYTAFFY 227

                        250
                 ....*....|...
gi 536036476 223 GGEMIAQGTPAEI 235
Cdd:COG1117  228 LGELVEFGPTEQI 240
ABCC_ATM1_transporter cd03253
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...
 13-236 1.08e-30

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213220 [Multi-domain]  Cd Length: 236  Bit Score: 114.25  E-value: 1.08e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  13 ALRNISFR-VPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLP 91
Cdd:cd03253    2 EFENVTFAyDPGRPVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDIREVTLDSLRRAIGVVP 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  92 QQLPPAEGmTVRELVaigRYpwhgalGRFGAADrEKVEEAISLVGLKPLAHRLVDS-----------LSGGERQRAWIAM 160
Cdd:cd03253   82 QDTVLFND-TIGYNI---RY------GRPDATD-EEVIEAAKAAQIHDKIMRFPDGydtivgerglkLSGGEKQRVAIAR 150

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 536036476 161 LVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERglTVIAVLHDINMAARyCDYLVALRGGEMIAQGTPAEIM 236
Cdd:cd03253  151 AILKNPPILLLDEATSALDTHTEREIQAALRDVSKGR--TTIVIAHRLSTIVN-ADKIIVLKDGRIVERGTHEELL 223
ABCC_bacteriocin_exporters cd03245
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...
 12-230 1.42e-30

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.


Pssm-ID: 213212 [Multi-domain]  Cd Length: 220  Bit Score: 113.45  E-value: 1.42e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  12 FALRNISFRVPG--RTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAY 89
Cdd:cd03245    3 IEFRNVSFSYPNqeIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQLDPADLRRNIGY 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  90 LPQQLPPAEGmTVRELVAIGRypwhgalgrfGAADREKVEEAISLVGLKPLAHRLVD-----------SLSGGERQRAWI 158
Cdd:cd03245   83 VPQDVTLFYG-TLRDNITLGA----------PLADDERILRAAELAGVTDFVNKHPNgldlqigergrGLSGGQRQAVAL 151

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 536036476 159 AMLVAQDSRCLLLDEPTSALDIAHQVdvlSLVHRLSQE-RGLTVIAVLHDINMAArYCDYLVALRGGEMIAQG 230
Cdd:cd03245  152 ARALLNDPPILLLDEPTSAMDMNSEE---RLKERLRQLlGDKTLIIITHRPSLLD-LVDRIIVMDSGRIVADG 220
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 14-246 1.94e-30

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 118.59  E-value: 1.94e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSK-AFARKVAYLPQ 92
Cdd:COG3845    8 LRGITKRFGGVVANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGKPVRIRSPRdAIALGIGMVHQ 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  93 QLPPAEGMTVRELVAIGRYPWHGALGRFGAAdREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLD 172
Cdd:COG3845   88 HFMLVPNLTVAENIVLGLEPTKGGRLDRKAA-RARIRELSERYGLDVDPDAKVEDLSVGEQQRVEILKALYRGARILILD 166

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 536036476 173 EPTSALDIAHQVDVLSLVHRLSQErGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMRGETLEMIYG 246
Cdd:COG3845  167 EPTAVLTPQEADELFEILRRLAAE-GKSIIFITHKLREVMAIADRVTVLRRGKVVGTVDTAETSEEELAELMVG 239
cbiO PRK13638
energy-coupling factor ABC transporter ATP-binding protein;
12-242 2.68e-30

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184198 [Multi-domain]  Cd Length: 271  Bit Score: 114.33  E-value: 2.68e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  12 FALRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLEsWSSK---AFARKVA 88
Cdd:PRK13638   2 LATSDLWFRYQDEPVLKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKPLD-YSKRgllALRQQVA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  89 YLPQQlpPAEGMTVRELVAIGRYpwhgALGRFGAADRE---KVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQD 165
Cdd:PRK13638  81 TVFQD--PEQQIFYTDIDSDIAF----SLRNLGVPEAEitrRVDEALTLVDAQHFRHQPIQCLSHGQKKRVAIAGALVLQ 154

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 536036476 166 SRCLLLDEPTSALDIAHQVDVLSLVHRLSQErGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIM-RGETLE 242
Cdd:PRK13638 155 ARYLLLDEPTAGLDPAGRTQMIAIIRRIVAQ-GNHVIISSHDIDLIYEISDAVYVLRQGQILTHGAPGEVFaCTEAME 231
ABC_putative_ATPase cd03269
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...
 14-230 4.16e-30

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213236 [Multi-domain]  Cd Length: 210  Bit Score: 111.99  E-value: 4.16e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLeswsSKAFARKVAYLPQQ 93
Cdd:cd03269    3 VENVTKRFGRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPL----DIAARNRIGYLPEE 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  94 LPPAEGMTVRE-LVAIGRYpwHGaLGRFGAadREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLD 172
Cdd:cd03269   79 RGLYPKMKVIDqLVYLAQL--KG-LKKEEA--RRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLILD 153

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 536036476 173 EPTSALDIAHqVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQG 230
Cdd:cd03269  154 EPFSGLDPVN-VELLKDVIRELARAGKTVILSTHQMELVEELCDRVLLLNKGRAVLYG 210
MsbA_lipidA TIGR02203
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ...
 15-236 4.17e-30

lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 131258 [Multi-domain]  Cd Length: 571  Bit Score: 117.90  E-value: 4.17e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   15 RNISFRVPG--RTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQ 92
Cdd:TIGR02203 334 RNVTFRYPGrdRPALDSISLVIEPGETVALVGRSGSGKSTLVNLIPRFYEPDSGQILLDGHDLADYTLASLRRQVALVSQ 413

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   93 QLPPAEGmTVRELVAigrypwhgaLGRFGAADREKVEEAISLVGLKPLAHRLVDS-----------LSGGERQRAWIAML 161
Cdd:TIGR02203 414 DVVLFND-TIANNIA---------YGRTEQADRAEIERALAAAYAQDFVDKLPLGldtpigengvlLSGGQRQRLAIARA 483

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 536036476  162 VAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIA-VLHDINMAarycDYLVALRGGEMIAQGTPAEIM 236
Cdd:TIGR02203 484 LLKDAPILILDEATSALDNESERLVQAALERLMQGRTTLVIAhRLSTIEKA----DRIVVMDDGRIVERGTHNELL 555
ABCC_Glucan_exporter_like cd03254
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...
 15-236 5.75e-30

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213221 [Multi-domain]  Cd Length: 229  Bit Score: 111.93  E-value: 5.75e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  15 RNISFRV-PGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQQ 93
Cdd:cd03254    6 ENVNFSYdEKKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIRDISRKSLRSMIGVVLQD 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  94 LPPAEGmTVRELVAIGRypwhgalgrfGAADREKVEEAISLVGLKPLAHRLVD-----------SLSGGERQRAWIAMLV 162
Cdd:cd03254   86 TFLFSG-TIMENIRLGR----------PNATDEEVIEAAKEAGAHDFIMKLPNgydtvlgenggNLSQGERQLLAIARAM 154

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 536036476 163 AQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAvlHDINmAARYCDYLVALRGGEMIAQGTPAEIM 236
Cdd:cd03254  155 LRDPKILILDEATSNIDTETEKLIQEALEKLMKGRTSIIIA--HRLS-TIKNADKILVLDDGKIIEEGTHDELL 225
cbiO PRK13647
cobalt transporter ATP-binding subunit; Provisional
 14-232 7.50e-30

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237457 [Multi-domain]  Cd Length: 274  Bit Score: 112.91  E-value: 7.50e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVP-GRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAyLPQ 92
Cdd:PRK13647   7 VEDLHFRYKdGTKALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNAENEKWVRSKVG-LVF 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  93 QLPPAE--GMTVRELVAIGryPWHGALGRfgAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLL 170
Cdd:PRK13647  86 QDPDDQvfSSTVWDDVAFG--PVNMGLDK--DEVERRVEEALKAVRMWDFRDKPPYHLSYGQKKRVAIAGVLAMDPDVIV 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 536036476 171 LDEPTSALDIAHQVDVLSLVHRLSQErGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTP 232
Cdd:PRK13647 162 LDEPMAYLDPRGQETLMEILDRLHNQ-GKTVIVATHDVDLAAEWADQVIVLKEGRVLAEGDK 222
ABCC_Hemolysin cd03252
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...
 13-241 8.40e-30

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.


Pssm-ID: 213219 [Multi-domain]  Cd Length: 237  Bit Score: 111.81  E-value: 8.40e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  13 ALRNISFRV--PGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYL 90
Cdd:cd03252    2 TFEHVRFRYkpDGPVILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLALADPAWLRRQVGVV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  91 PQQLPPAEGmTVRELVAIGRypwhgalgrfGAADREKVEEAISLVGlkplAHRLV---------------DSLSGGERQR 155
Cdd:cd03252   82 LQENVLFNR-SIRDNIALAD----------PGMSMERVIEAAKLAG----AHDFIselpegydtivgeqgAGLSGGQRQR 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 156 AWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERglTVIAVLHDINmAARYCDYLVALRGGEMIAQGTPAEI 235
Cdd:cd03252  147 IAIARALIHNPRILIFDEATSALDYESEHAIMRNMHDICAGR--TVIIIAHRLS-TVKNADRIIVMEKGRIVEQGSHDEL 223


                 ....*.
gi 536036476 236 MRGETL 241
Cdd:cd03252  224 LAENGL 229
ABC_FtsE cd03292
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...
 14-226 1.13e-29

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages


Pssm-ID: 213259 [Multi-domain]  Cd Length: 214  Bit Score: 110.96  E-value: 1.13e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTL-LHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLeswsSKAFARKVAYLPQ 92
Cdd:cd03292    3 FINVTKTYPNGTAaLDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDV----SDLRGRAIPYLRR 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  93 QLppaeGM-----------TVRELVAIgrypwhgALGRFGAADRE---KVEEAISLVGLKPLAHRLVDSLSGGERQRAWI 158
Cdd:cd03292   79 KI----GVvfqdfrllpdrNVYENVAF-------ALEVTGVPPREirkRVPAALELVGLSHKHRALPAELSGGEQQRVAI 147

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 536036476 159 AMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQeRGLTVIAVLHDINMAARYCDYLVALRGGEM 226
Cdd:cd03292  148 ARAIVNSPTILIADEPTGNLDPDTTWEIMNLLKKINK-AGTTVVVATHAKELVDTTRHRVIALERGKL 214
thiQ TIGR01277
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ...
 31-230 2.42e-29

thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]


Pssm-ID: 130344 [Multi-domain]  Cd Length: 213  Bit Score: 109.95  E-value: 2.42e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   31 SLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQplESWSSKAFARKVAYLPQQLPPAEGMTVRELVAIGR 110
Cdd:TIGR01277  18 DLNVADGEIVAIMGPSGAGKSTLLNLIAGFIEPASGSIKVNDQ--SHTGLAPYQRPVSMLFQENNLFAHLTVRQNIGLGL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  111 YPwhgALgRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLV 190
Cdd:TIGR01277  96 HP---GL-KLNAEQQEKVVDAAQQVGIADYLDRLPEQLSGGQRQRVALARCLVRPNPILLLDEPFSALDPLLREEMLALV 171

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 536036476  191 HRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQG 230
Cdd:TIGR01277 172 KQLCSERQRTLLMVTHHLSDARAIASQIAVVSQGKIKVVS 211
nickel_nikE TIGR02769
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ...
 25-229 2.46e-29

nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131816 [Multi-domain]  Cd Length: 265  Bit Score: 111.44  E-value: 2.46e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   25 TLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQP---LESWSSKAFARKVAYLPQQLPPAEG-- 99
Cdd:TIGR02769  25 PVLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQGTVSFRGQDlyqLDRKQRRAFRRDVQLVFQDSPSAVNpr 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  100 MTVRELVaigRYPWHGALGRFGAADREKVEEAISLVGLKP-LAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSAL 178
Cdd:TIGR02769 105 MTVRQII---GEPLRHLTSLDESEQKARIAELLDMVGLRSeDADKLPRQLSGGQLQRINIARALAVKPKLIVLDEAVSNL 181

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 536036476  179 DIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQ 229
Cdd:TIGR02769 182 DMVLQAVILELLRKLQQAFGTAYLFITHDLRLVQSFCQRVAVMDKGQIVEE 232
ABC_ModC_like cd03299
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...
 12-235 3.09e-29

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213266 [Multi-domain]  Cd Length: 235  Bit Score: 110.50  E-value: 3.09e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  12 FALRNISFRVPgrtllhplsltfpAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAfaRKVAYLP 91
Cdd:cd03299   13 FKLKNVSLEVE-------------RGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDITNLPPEK--RDISYVP 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  92 QQLPPAEGMTVRELVAIG----RYPwhgalgrfGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSR 167
Cdd:cd03299   78 QNYALFPHMTVYKNIAYGlkkrKVD--------KKEIERKVLEIAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPK 149

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 536036476 168 CLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEI 235
Cdd:cd03299  150 ILLLDEPFSALDVRTKEKLREELKKIRKEFGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEEV 217
PRK10247 PRK10247
putative ABC transporter ATP-binding protein YbbL; Provisional
 6-226 5.29e-29

putative ABC transporter ATP-binding protein YbbL; Provisional


Pssm-ID: 182331 [Multi-domain]  Cd Length: 225  Bit Score: 109.42  E-value: 5.29e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   6 NHSDTTFALRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFAR 85
Cdd:PRK10247   2 QENSPLLQLQNVGYLAGDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDISTLKPEIYRQ 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  86 KVAYLPQQlPPAEGMTVRELVAigrYPWhgaLGRFGAADREKVEEAISLVGL-KPLAHRLVDSLSGGERQRAWIAMLVAQ 164
Cdd:PRK10247  82 QVSYCAQT-PTLFGDTVYDNLI---FPW---QIRNQQPDPAIFLDDLERFALpDTILTKNIAELSGGEKQRISLIRNLQF 154

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 536036476 165 DSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINmAARYCDYLVAL--RGGEM 226
Cdd:PRK10247 155 MPKVLLLDEITSALDESNKHNVNEIIHRYVREQNIAVLWVTHDKD-EINHADKVITLqpHAGEM 217
anch_rpt_ABC TIGR03771
anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ...
 36-247 7.61e-29

anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ATP-binding cassette subunit of binding protein-dependent ABC transporter complex that strictly co-occurs with TIGR03769. TIGRFAMs model TIGR03769 describes a protein domain that occurs singly or as one of up to three repeats in proteins of a number of Actinobacteria, including Propionibacterium acnes KPA171202. The TIGR03769 domain occurs both in an adjacent gene for the substrate-binding protein and in additional (often nearby) proteins, often with LPXTG-like sortase recognition signals. Homologous ATP-binding subunits outside the scope of this family include manganese transporter MntA in Synechocystis sp. PCC 6803 and chelated iron transporter subunits. The function of this transporter complex is unknown. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 163483 [Multi-domain]  Cd Length: 223  Bit Score: 109.17  E-value: 7.61e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   36 AGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPleswsSKAFARKVAYLPQQLPPAEG--MTVRELVAIGRYPW 113
Cdd:TIGR03771   5 KGELLGLLGPNGAGKTTLLRAILGLIPPAKGTVKVAGAS-----PGKGWRHIGYVPQRHEFAWDfpISVAHTVMSGRTGH 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  114 HGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRL 193
Cdd:TIGR03771  80 IGWLRRPCVADFAAVRDALRRVGLTELADRPVGELSGGQRQRVLVARALATRPSVLLLDEPFTGLDMPTQELLTELFIEL 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 536036476  194 SQErGLTVIAVLHDINMAARYCDYLVaLRGGEMIAQGTPAEIMRGETLEMIYGI 247
Cdd:TIGR03771 160 AGA-GTAILMTTHDLAQAMATCDRVV-LLNGRVIADGTPQQLQDPAPWMTTFGV 211
ABCC_Protease_Secretion cd03246
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...
 12-226 9.40e-29

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.


Pssm-ID: 213213 [Multi-domain]  Cd Length: 173  Bit Score: 107.30  E-value: 9.40e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  12 FALRNISFRVPG--RTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAY 89
Cdd:cd03246    1 LEVENVSFRYPGaePPVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQWDPNELGDHVGY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  90 LPQQLPPAEGmTVRELVaigrypwhgalgrfgaadrekveeaislvglkplahrlvdsLSGGERQRAWIAMLVAQDSRCL 169
Cdd:cd03246   81 LPQDDELFSG-SIAENI-----------------------------------------LSGGQRQRLGLARALYGNPRIL 118

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 536036476 170 LLDEPTSALDIAHQVDVLSLVHRLsQERGLTVIAVLHDINMAARyCDYLVALRGGEM 226
Cdd:cd03246  119 VLDEPNSHLDVEGERALNQAIAAL-KAAGATRIVIAHRPETLAS-ADRILVLEDGRV 173
YbbA COG4181
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ...
 5-234 1.59e-28

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443338 [Multi-domain]  Cd Length: 233  Bit Score: 108.29  E-value: 1.59e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   5 TNHSDTTFALRNISFRVPGR----TLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSS 80
Cdd:COG4181    2 SSSSAPIIELRGLTKTVGTGagelTILKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQDLFALDE 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  81 KAFAR----KVAYLPQ--QLPPAegMTVRELVAIgryPwhgaLGRFGAAD-REKVEEAISLVGLKPLAHRLVDSLSGGER 153
Cdd:COG4181   82 DARARlrarHVGFVFQsfQLLPT--LTALENVML---P----LELAGRRDaRARARALLERVGLGHRLDHYPAQLSGGEQ 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 154 QRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARyCDYLVALRGGEMIAQGTPA 233
Cdd:COG4181  153 QRVALARAFATEPAILFADEPTGNLDAATGEQIIDLLFELNRERGTTLVLVTHDPALAAR-CDRVLRLRAGRLVEDTAAT 231


                 .
gi 536036476 234 E 234
Cdd:COG4181  232 A 232
cbiO PRK13639
cobalt transporter ATP-binding subunit; Provisional
 15-235 2.11e-28

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184199 [Multi-domain]  Cd Length: 275  Bit Score: 109.01  E-value: 2.11e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  15 RNISFRVP-GRTLLHPLSLTFPAGKVTGLIGHNGSGKSTL-LKMLGRHQPpSEGEILLDAQPLeSWSSKAF--ARKVAYL 90
Cdd:PRK13639   5 RDLKYSYPdGTEALKGINFKAEKGEMVALLGPNGAGKSTLfLHFNGILKP-TSGEVLIKGEPI-KYDKKSLleVRKTVGI 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  91 PQQLPPAE--GMTVRELVAIGryPWHgaLGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRC 168
Cdd:PRK13639  83 VFQNPDDQlfAPTVEEDVAFG--PLN--LGLSKEEVEKRVKEALKAVGMEGFENKPPHHLSGGQKKRVAIAGILAMKPEI 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 536036476 169 LLLDEPTSALDIAHQVDVLSLVHRLSQErGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEI 235
Cdd:PRK13639 159 IVLDEPTSGLDPMGASQIMKLLYDLNKE-GITIIISTHDVDLVPVYADKVYVMSDGKIIKEGTPKEV 224
cbiO PRK13640
energy-coupling factor transporter ATPase;
8-241 2.29e-28

energy-coupling factor transporter ATPase;


Pssm-ID: 184200 [Multi-domain]  Cd Length: 282  Bit Score: 109.12  E-value: 2.29e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   8 SDTTFALRNISFRVPG--RTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPP---SEGEILLDAQPLESWSSKA 82
Cdd:PRK13640   2 KDNIVEFKHVSFTYPDskKPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPddnPNSKITVDGITLTAKTVWD 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  83 FARKVAYLPQQlPPAE--GMTVRELVAIG---RypwhgalgrfgAADREK----VEEAISLVGLKPLAHRLVDSLSGGER 153
Cdd:PRK13640  82 IREKVGIVFQN-PDNQfvGATVGDDVAFGlenR-----------AVPRPEmikiVRDVLADVGMLDYIDSEPANLSGGQK 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 154 QRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAArYCDYLVALRGGEMIAQGTPA 233
Cdd:PRK13640 150 QRVAIAGILAVEPKIIILDESTSMLDPAGKEQILKLIRKLKKKNNLTVISITHDIDEAN-MADQVLVLDDGKLLAQGSPV 228


                 ....*...
gi 536036476 234 EIMRGETL 241
Cdd:PRK13640 229 EIFSKVEM 236
ABCC_MsbA cd03251
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...
 14-236 2.59e-28

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213218 [Multi-domain]  Cd Length: 234  Bit Score: 108.09  E-value: 2.59e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPG--RTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLP 91
Cdd:cd03251    3 FKNVTFRYPGdgPPVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDVRDYTLASLRRQIGLVS 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  92 QQLPPAEGmTVRELVAIGRypwHGalgrfgaADREKVEEAISLVGlkplAHRLVDS---------------LSGGERQRA 156
Cdd:cd03251   83 QDVFLFND-TVAENIAYGR---PG-------ATREEVEEAARAAN----AHEFIMElpegydtvigergvkLSGGQRQRI 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 157 WIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERglTVIAVLHDINmAARYCDYLVALRGGEMIAQGTPAEIM 236
Cdd:cd03251  148 AIARALLKDPPILILDEATSALDTESERLVQAALERLMKNR--TTFVIAHRLS-TIENADRIVVLEDGKIVERGTHEELL 224
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 16-235 2.91e-28

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 112.47  E-value: 2.91e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  16 NISFRVPGRT--LLHPLSLTFPAGKVTGLIGHNGSGKS----TLLKMLGRHQPPSEGEILLDAQPLESWSSKAFAR---- 85
Cdd:COG4172   13 SVAFGQGGGTveAVKGVSFDIAAGETLALVGESGSGKSvtalSILRLLPDPAAHPSGSILFDGQDLLGLSERELRRirgn 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  86 KVAYLPQqlppaEGMT-----------VRELVAIgrypwHGALGRfgAADREKVEEAISLVGLKPLAHRLvDS----LSG 150
Cdd:COG4172   93 RIAMIFQ-----EPMTslnplhtigkqIAEVLRL-----HRGLSG--AAARARALELLERVGIPDPERRL-DAyphqLSG 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 151 GERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQG 230
Cdd:COG4172  160 GQRQRVMIAMALANEPDLLIADEPTTALDVTVQAQILDLLKDLQRELGMALLLITHDLGVVRRFADRVAVMRQGEIVEQG 239


                 ....*
gi 536036476 231 TPAEI 235
Cdd:COG4172  240 PTAEL 244
LPS_export_lptB TIGR04406
LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ...
 11-245 7.33e-28

LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ATP-binding cassette protein of an ABC transporter involved in lipopolysaccharide export. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 275199 [Multi-domain]  Cd Length: 239  Bit Score: 106.97  E-value: 7.33e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   11 TFALRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARK-VAY 89
Cdd:TIGR04406   1 TLVAENLIKSYKKRKVVNDVSLSVKSGEIVGLLGPNGAGKTTSFYMIVGLVRPDAGKILIDGQDITHLPMHERARLgIGY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   90 LPQQLPPAEGMTVRE-LVAIGRYpwHGALGRfgAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRC 168
Cdd:TIGR04406  81 LPQEASIFRKLTVEEnIMAVLEI--RKDLDR--AEREERLEALLEEFQISHLRDNKAMSLSGGERRRVEIARALATNPKF 156

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 536036476  169 LLLDEPTSALDIAHQVDVLSLVHRLsQERGLTVIAVLHDINMAARYCD--YLVAlrGGEMIAQGTPAEIMRGETLEMIY 245
Cdd:TIGR04406 157 ILLDEPFAGVDPIAVGDIKKIIKHL-KERGIGVLITDHNVRETLDICDraYIIS--DGKVLAEGTPAEIVANEKVRRVY 232
cbiO PRK13652
cobalt transporter ATP-binding subunit; Provisional
 13-253 9.18e-28

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 172200 [Multi-domain]  Cd Length: 277  Bit Score: 107.58  E-value: 9.18e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  13 ALRNISFRVPGRTLLhplsltfpagkvtGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAfARKVAYLPQ 92
Cdd:PRK13652  19 ALNNINFIAPRNSRI-------------AVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPITKENIRE-VRKFVGLVF 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  93 QLPPAE--GMTVRELVAIGryPWHgaLGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLL 170
Cdd:PRK13652  85 QNPDDQifSPTVEQDIAFG--PIN--LGLDEETVAHRVSSALHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQVLV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 171 LDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMRGETLEMIYGIPMG 250
Cdd:PRK13652 161 LDEPTAGLDPQGVKELIDFLNDLPETYGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEIFLQPDLLARVHLDLP 240


                 ...
gi 536036476 251 ILP 253
Cdd:PRK13652 241 SLP 243
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 13-237 1.08e-27

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 110.93  E-value: 1.08e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  13 ALRNISFRV-PGRTLlhplsltfpagkvtGLIGHNGSGKSTLLKMLGRHQPpSEGEILLDAQPLESWSSKAFA---RKVa 88
Cdd:COG4172  301 AVDGVSLTLrRGETL--------------GLVGESGSGKSTLGLALLRLIP-SEGEIRFDGQDLDGLSRRALRplrRRM- 364

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  89 ylpqQ---------LPPAegMTVRELVAIGRYPWHGALGRfgAADREKVEEAISLVGLKP-LAHRLVDSLSGGERQRAWI 158
Cdd:COG4172  365 ----QvvfqdpfgsLSPR--MTVGQIIAEGLRVHGPGLSA--AERRARVAEALEEVGLDPaARHRYPHEFSGGQRQRIAI 436

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 536036476 159 AMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMR 237
Cdd:COG4172  437 ARALILEPKLLVLDEPTSALDVSVQAQILDLLRDLQREHGLAYLFISHDLAVVRALAHRVMVMKDGKVVEQGPTEQVFD 515
type_I_sec_PrtD TIGR01842
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ...
 11-236 1.24e-27

type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 200134 [Multi-domain]  Cd Length: 544  Bit Score: 110.90  E-value: 1.24e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   11 TFALRNISFRVPG--RTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVA 88
Cdd:TIGR01842 316 HLSVENVTIVPPGgkKPTLRGISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPPTSGSVRLDGADLKQWDRETFGKHIG 395

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   89 YLPQQLPPAEGmTVRELVAigrypwhgalgRFG-AADREKVEEAISLVGLKPLAHRLVD-----------SLSGGERQRA 156
Cdd:TIGR01842 396 YLPQDVELFPG-TVAENIA-----------RFGeNADPEKIIEAAKLAGVHELILRLPDgydtvigpggaTLSGGQRQRI 463

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  157 WIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLsQERGLTVIAVLHDINMAARyCDYLVALRGGEMIAQGTPAEIM 236
Cdd:TIGR01842 464 ALARALYGDPKLVVLDEPNSNLDEEGEQALANAIKAL-KARGITVVVITHRPSLLGC-VDKILVLQDGRIARFGERDEVL 541
cbiO PRK13637
energy-coupling factor transporter ATPase;
27-248 1.74e-27

energy-coupling factor transporter ATPase;


Pssm-ID: 237455 [Multi-domain]  Cd Length: 287  Bit Score: 107.06  E-value: 1.74e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  27 LHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSK-AFARKVAYLPQQLPPAEGM--TVR 103
Cdd:PRK13637  23 LDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDITDKKVKlSDIRKKVGLVFQYPEYQLFeeTIE 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 104 ELVAIGrypwhgaLGRFGAADRE---KVEEAISLVGLK--PLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSAL 178
Cdd:PRK13637 103 KDIAFG-------PINLGLSEEEienRVKRAMNIVGLDyeDYKDKSPFELSGGQKRRVAIAGVVAMEPKILILDEPTAGL 175

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 536036476 179 DIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMRG-ETLEMI-YGIP 248
Cdd:PRK13637 176 DPKGRDEILNKIKELHKEYNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGTPREVFKEvETLESIgLAVP 247
ABC_HisP_GlnQ cd03262
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...
 14-225 1.79e-27

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.


Pssm-ID: 213229 [Multi-domain]  Cd Length: 213  Bit Score: 105.30  E-value: 1.79e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESwSSKAFA---RKVAYL 90
Cdd:cd03262    3 IKNLHKSFGDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKLTD-DKKNINelrQKVGMV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  91 PQQLPPAEGMTVRELVAIGryP-WhgALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCL 169
Cdd:cd03262   82 FQQFNLFPHLTVLENITLA--PiK--VKGMSKAEAEERALELLEKVGLADKADAYPAQLSGGQQQRVAIARALAMNPKVM 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 536036476 170 LLDEPTSALDIAHQVDVLSLVHRLSQErGLTVIAVLHDINMAARYCDYLVALRGGE 225
Cdd:cd03262  158 LFDEPTSALDPELVGEVLDVMKDLAEE-GMTMVVVTHEMGFAREVADRVIFMDDGR 212
ABC_RNaseL_inhibitor_domain2 cd03237
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 33-223 1.94e-27

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213204 [Multi-domain]  Cd Length: 246  Bit Score: 105.95  E-value: 1.94e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  33 TFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQpleswsskafarKVAYLPQQLPPAEGMTVRELVaigryp 112
Cdd:cd03237   21 SISESEVIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIELD------------TVSYKPQYIKADYEGTVRDLL------ 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 113 wHGALGRFGAADREKVEEAISLvGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHR 192
Cdd:cd03237   83 -SSITKDFYTHPYFKTEIAKPL-QIEQILDREVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLDVEQRLMASKVIRR 160

                        170       180       190
                 ....*....|....*....|....*....|.
gi 536036476 193 LSQERGLTVIAVLHDINMAARYCDYLVALRG 223
Cdd:cd03237  161 FAENNEKTAFVVEHDIIMIDYLADRLIVFEG 191
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 25-230 2.48e-27

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 109.79  E-value: 2.48e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  25 TLLHPLSLTFPAGKVTGLIGHNGSGKST----LLKMLgrhqpPSEGEILLDAQPLESWSSKA---FARKVAYLPQQ---- 93
Cdd:PRK15134 300 VVVKNISFTLRPGETLGLVGESGSGKSTtglaLLRLI-----NSQGEIWFDGQPLHNLNRRQllpVRHRIQVVFQDpnss 374

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  94 LPPAegMTVRELVAIGRYPWHGALGrfgAADRE-KVEEAISLVGLKP-LAHRLVDSLSGGERQRAWIAMLVAQDSRCLLL 171
Cdd:PRK15134 375 LNPR--LNVLQIIEEGLRVHQPTLS---AAQREqQVIAVMEEVGLDPeTRHRYPAEFSGGQRQRIAIARALILKPSLIIL 449

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 536036476 172 DEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQG 230
Cdd:PRK15134 450 DEPTSSLDKTVQAQILALLKSLQQKHQLAYLFISHDLHVVRALCHQVIVLRQGEVVEQG 508
PhnK COG1101
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 24-227 3.18e-27

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 440718 [Multi-domain]  Cd Length: 264  Bit Score: 105.55  E-value: 3.18e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  24 RTLLHPLSLTFPAGK-VTgLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQ--QLPPAEGM 100
Cdd:COG1101   19 KRALDGLNLTIEEGDfVT-VIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKDVTKLPEYKRAKYIGRVFQdpMMGTAPSM 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 101 TVRELVAI-----GRYPWHGALGRfgaADREKVEEAISLVGLKpLAHRL---VDSLSGGERQrAwIAMLVA--QDSRCLL 170
Cdd:COG1101   98 TIEENLALayrrgKRRGLRRGLTK---KRRELFRELLATLGLG-LENRLdtkVGLLSGGQRQ-A-LSLLMAtlTKPKLLL 171

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 536036476 171 LDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMI 227
Cdd:COG1101  172 LDEHTAALDPKTAALVLELTEKIVEENNLTTLMVTHNMEQALDYGNRLIMMHEGRII 228
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 14-227 4.18e-27

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 109.38  E-value: 4.18e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEIlldaqpleSWSSKAfarKVAYLPQ- 92
Cdd:COG0488  318 LEGLSKSYGDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTV--------KLGETV---KIGYFDQh 386

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  93 --QLPPaeGMTVRELV---AIGRYPWH--GALGRFG-AADRekveeaislvglkplAHRLVDSLSGGERQRAWIAMLVAQ 164
Cdd:COG0488  387 qeELDP--DKTVLDELrdgAPGGTEQEvrGYLGRFLfSGDD---------------AFKPVGVLSGGEKARLALAKLLLS 449

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 536036476 165 DSRCLLLDEPTSALDIAhQVDVLslvhrlsqERGL-----TVIAVLHDinmaaRY-----CDYLVALRGGEMI 227
Cdd:COG0488  450 PPNVLLLDEPTNHLDIE-TLEAL--------EEALddfpgTVLLVSHD-----RYfldrvATRILEFEDGGVR 508
AppF COG4608
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ...
 31-210 4.89e-27

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443658 [Multi-domain]  Cd Length: 329  Bit Score: 106.74  E-value: 4.89e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  31 SLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSS---KAFARKVAYLPQ----QLPPaeGMTVR 103
Cdd:COG4608   38 SFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDGQDITGLSGrelRPLRRRMQMVFQdpyaSLNP--RMTVG 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 104 ELVAigrYPW--HGALGRfgAADREKVEEAISLVGLKP-LAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDI 180
Cdd:COG4608  116 DIIA---EPLriHGLASK--AERRERVAELLELVGLRPeHADRYPHEFSGGQRQRIGIARALALNPKLIVCDEPVSALDV 190

                        170       180       190
                 ....*....|....*....|....*....|
gi 536036476 181 AHQVDVLSLVHRLSQERGLTVIAVLHDINM 210
Cdd:COG4608  191 SIQAQVLNLLEDLQDELGLTYLFISHDLSV 220
glnQ PRK09493
glutamine ABC transporter ATP-binding protein GlnQ;
14-236 7.20e-27

glutamine ABC transporter ATP-binding protein GlnQ;


Pssm-ID: 181906 [Multi-domain]  Cd Length: 240  Bit Score: 104.40  E-value: 7.20e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSK--AFARKVAYLP 91
Cdd:PRK09493   4 FKNVSKHFGPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVNDPKVDerLIRQEAGMVF 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  92 QQLPPAEGMTVRELVAIGryPWHgALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLL 171
Cdd:PRK09493  84 QQFYLFPHLTALENVMFG--PLR-VRGASKEEAEKQARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKLMLF 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 536036476 172 DEPTSALDIAHQVDVLSLVHRLSQErGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIM 236
Cdd:PRK09493 161 DEPTSALDPELRHEVLKVMQDLAEE-GMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDGDPQVLI 224
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
13-228 1.09e-26

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 108.07  E-value: 1.09e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  13 ALRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSK-AFARKVAYLP 91
Cdd:PRK11288   6 SFDGIGKTFPGVKALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQEMRFASTTaALAAGVAIIY 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  92 QQLPPAEGMTVRELVAIGRYPwhgalGRFGAADREK----VEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSR 167
Cdd:PRK11288  86 QELHLVPEMTVAENLYLGQLP-----HKGGIVNRRLlnyeAREQLEHLGVDIDPDTPLKYLSIGQRQMVEIAKALARNAR 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 536036476 168 CLLLDEPTSALDiAHQVDVL-SLVHRLSQErGLTVIAVLHDINMAARYCDYLVALRGGEMIA 228
Cdd:PRK11288 161 VIAFDEPTSSLS-AREIEQLfRVIRELRAE-GRVILYVSHRMEEIFALCDAITVFKDGRYVA 220
nikE PRK10419
nickel ABC transporter ATP-binding protein NikE;
22-227 1.19e-26

nickel ABC transporter ATP-binding protein NikE;


Pssm-ID: 236689 [Multi-domain]  Cd Length: 268  Bit Score: 104.38  E-value: 1.19e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  22 PGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSS---KAFARKVAYLPQQLPPAE 98
Cdd:PRK10419  23 QHQTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLAKLNRaqrKAFRRDIQMVFQDSISAV 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  99 G--MTVRELVaigRYPWHGALGRFGAADREKVEEAISLVGLKP-LAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPT 175
Cdd:PRK10419 103 NprKTVREII---REPLRHLLSLDKAERLARASEMLRAVDLDDsVLDKRPPQLSGGQLQRVCLARALAVEPKLLILDEAV 179

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 536036476 176 SALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMI 227
Cdd:PRK10419 180 SNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERFCQRVMVMDNGQIV 231
TauB COG4525
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
14-208 2.25e-26

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443596 [Multi-domain]  Cd Length: 262  Bit Score: 103.40  E-value: 2.25e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPG----RTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKafaRKVAY 89
Cdd:COG4525    6 VRHVSVRYPGggqpQPALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLDGVPVTGPGAD---RGVVF 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  90 LPQQLPPaeGMTVRELVAIGRypwhgALGRFGAADREKV-EEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRC 168
Cdd:COG4525   83 QKDALLP--WLNVLDNVAFGL-----RLRGVPKAERRARaEELLALVGLADFARRRIWQLSGGMRQRVGIARALAADPRF 155

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 536036476 169 LLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDI 208
Cdd:COG4525  156 LLMDEPFGALDALTREQMQELLLDVWQRTGKGVFLITHSV 195
ABCG_EPDR cd03213
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...
 11-230 3.22e-26

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.


Pssm-ID: 213180 [Multi-domain]  Cd Length: 194  Bit Score: 101.47  E-value: 3.22e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  11 TFALRNISFRVPG------RTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKML-GRHQPPS-EGEILLDAQPLeswSSKA 82
Cdd:cd03213    3 TLSFRNLTVTVKSspsksgKQLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALaGRRTGLGvSGEVLINGRPL---DKRS 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  83 FARKVAYLPQQLPPAEGMTVRElvaigrypwhgALgRFGAADRekveeaislvglkplahrlvdSLSGGERQRAWIAMLV 162
Cdd:cd03213   80 FRKIIGYVPQDDILHPTLTVRE-----------TL-MFAAKLR---------------------GLSGGERKRVSIALEL 126

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 536036476 163 AQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQErGLTVIAVLH-----DINMaaryCDYLVALRGGEMIAQG 230
Cdd:cd03213  127 VSNPSLLFLDEPTSGLDSSSALQVMSLLRRLADT-GRTIICSIHqpsseIFEL----FDKLLLLSQGRVIYFG 194
LolD_lipo_ex TIGR02211
lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ...
 25-213 3.76e-26

lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ABC transporter family (pfam00005). LolD is involved in localization of lipoproteins in some bacteria. It works with a transmembrane protein LolC, which in some species is a paralogous pair LolC and LolE. Depending on whether the residue immediately following the new, modified N-terminal Cys residue, the nascent lipoprotein may be carried further by LolA and LolB to the outer membrane, or remain at the inner membrane. The top scoring proteins excluded by this model include homologs from the archaeal genus Methanosarcina. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 131266 [Multi-domain]  Cd Length: 221  Bit Score: 102.04  E-value: 3.76e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   25 TLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFA----RKVAYLPQ--QLPPAe 98
Cdd:TIGR02211  19 RVLKGVSLSIGKGEIVAIVGSSGSGKSTLLHLLGGLDNPTSGEVLFNGQSLSKLSSNERAklrnKKLGFIYQfhHLLPD- 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   99 gMTVRELVAIgryPWhgALGRFGAAD-REKVEEAISLVGLKplaHRLV---DSLSGGERQRAWIAMLVAQDSRCLLLDEP 174
Cdd:TIGR02211  98 -FTALENVAM---PL--LIGKKSVKEaKERAYEMLEKVGLE---HRINhrpSELSGGERQRVAIARALVNQPSLVLADEP 168

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 536036476  175 TSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAAR 213
Cdd:TIGR02211 169 TGNLDNNNAKIIFDLMLELNRELNTSFLVVTHDLELAKK 207
ABC_NatA_like cd03267
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...
 30-230 8.90e-26

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.


Pssm-ID: 213234 [Multi-domain]  Cd Length: 236  Bit Score: 101.25  E-value: 8.90e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  30 LSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEI-LLDAQPLESwsSKAFARKVAYLPQQ-------LPPAEGMT 101
Cdd:cd03267   40 ISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVrVAGLVPWKR--RKKFLRRIGVVFGQktqlwwdLPVIDSFY 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 102 VreLVAIGRYPWhgalGRFgaadREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIA 181
Cdd:cd03267  118 L--LAAIYDLPP----ARF----KKRLDELSELLDLEELLDTPVRQLSLGQRMRAEIAAALLHEPEILFLDEPTIGLDVV 187

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 536036476 182 HQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQG 230
Cdd:cd03267  188 AQENIRNFLKEYNRERGTTVLLTSHYMKDIEALARRVLVIDKGRLLYDG 236
potG PRK11607
putrescine ABC transporter ATP-binding subunit PotG;
14-235 1.25e-25

putrescine ABC transporter ATP-binding subunit PotG;


Pssm-ID: 183226 [Multi-domain]  Cd Length: 377  Bit Score: 103.76  E-value: 1.25e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLEswSSKAFARKVAYLPQQ 93
Cdd:PRK11607  22 IRNLTKSFDGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDLS--HVPPYQRPINMMFQS 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  94 LPPAEGMTVRELVAIGRYpwHGALGRFGAADRekVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDE 173
Cdd:PRK11607 100 YALFPHMTVEQNIAFGLK--QDKLPKAEIASR--VNEMLGLVHMQEFAKRKPHQLSGGQRQRVALARSLAKRPKLLLLDE 175

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 174 PTSALDIA----HQVDVLSLVHRLsqerGLTVIAVLHD----INMAARycdyLVALRGGEMIAQGTPAEI 235
Cdd:PRK11607 176 PMGALDKKlrdrMQLEVVDILERV----GVTCVMVTHDqeeaMTMAGR----IAIMNRGKFVQIGEPEEI 237
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
1-235 1.41e-25

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 103.49  E-value: 1.41e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   1 MQEYTNHSDTTFALRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQ-----PL 75
Cdd:PRK09452   4 LNKQPSSLSPLVELRGISKSFDGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQdithvPA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  76 EswsskafARKVAYLPQQ--LPPAegMTVRELVAIG-RypwhgaLGRFGAAD-REKVEEAISLVGLKPLAHRLVDSLSGG 151
Cdd:PRK09452  84 E-------NRHVNTVFQSyaLFPH--MTVFENVAFGlR------MQKTPAAEiTPRVMEALRMVQLEEFAQRKPHQLSGG 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 152 ERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGT 231
Cdd:PRK09452 149 QQQRVAIARAVVNKPKVLLLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRIEQDGT 228


                 ....
gi 536036476 232 PAEI 235
Cdd:PRK09452 229 PREI 232
CydC TIGR02868
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...
 14-207 1.58e-25

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.


Pssm-ID: 274331 [Multi-domain]  Cd Length: 530  Bit Score: 104.75  E-value: 1.58e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   14 LRNISFRVPG-RTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQ 92
Cdd:TIGR02868 337 LRDLSAGYPGaPPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSSLDQDEVRRRVSVCAQ 416

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   93 QlPPAEGMTVRELVAIGRypwhgalgrfGAADREKVEEAISLVGLKPLAHRLVD-----------SLSGGERQRAWIAML 161
Cdd:TIGR02868 417 D-AHLFDTTVRENLRLAR----------PDATDEELWAALERVGLADWLRALPDgldtvlgeggaRLSGGERQRLALARA 485

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 536036476  162 VAQDSRCLLLDEPTSALDIAHQVDVLSLVhrLSQERGLTVIAVLHD 207
Cdd:TIGR02868 486 LLADAPILLLDEPTEHLDAETADELLEDL--LAALSGRTVVLITHH 529
ntrCD TIGR01184
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ...
 27-255 2.00e-25

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]


Pssm-ID: 130252 [Multi-domain]  Cd Length: 230  Bit Score: 100.23  E-value: 2.00e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   27 LHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKafaRKVAYLPQQLPPaeGMTVRELV 106
Cdd:TIGR01184   1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGKQITEPGPD---RMVVFQNYSLLP--WLTVRENI 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  107 AIGRypwHGALGRFGAADREK-VEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVD 185
Cdd:TIGR01184  76 ALAV---DRVLPDLSKSERRAiVEEHIALVGLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRGN 152

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 536036476  186 VLSLVHRLSQERGLTVIAVLHDINMAARYCDYLValrggeMIAQGTPAEImrGETLEMIYGIP---MGILPHP 255
Cdd:TIGR01184 153 LQEELMQIWEEHRVTVLMVTHDVDEALLLSDRVV------MLTNGPAANI--GQILEVPFPRPrdrLEVVEDP 217
ABC_MalK_N cd03301
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...
 14-213 2.01e-25

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.


Pssm-ID: 213268 [Multi-domain]  Cd Length: 213  Bit Score: 99.64  E-value: 2.01e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAfaRKVAYLPQQ 93
Cdd:cd03301    3 LENVTKRFGNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDVTDLPPKD--RDIAMVFQN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  94 LPPAEGMTVRELVAIGRypwhgALGRFGAAD-REKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLD 172
Cdd:cd03301   81 YALYPHMTVYDNIAFGL-----KLRKVPKDEiDERVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIVREPKVFLMD 155

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 536036476 173 EPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHD----INMAAR 213
Cdd:cd03301  156 EPLSNLDAKLRVQMRAELKRLQQRLGTTTIYVTHDqveaMTMADR 200
LptB COG1137
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ...
 15-235 2.60e-25

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440752 [Multi-domain]  Cd Length: 240  Bit Score: 100.10  E-value: 2.60e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  15 RNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARK-VAYLPQq 93
Cdd:COG1137    7 ENLVKSYGKRTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDITHLPMHKRARLgIGYLPQ- 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  94 lppaE-----GMTVRE-LVAIGRYpwhgaLGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSR 167
Cdd:COG1137   86 ----EasifrKLTVEDnILAVLEL-----RKLSKKEREERLEELLEEFGITHLRKSKAYSLSGGERRRVEIARALATNPK 156

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 536036476 168 CLLLDEPTSALD-IAhqV-DVLSLVHRLsQERGltvIAVL---HDINMAARYCD--YLvaLRGGEMIAQGTPAEI 235
Cdd:COG1137  157 FILLDEPFAGVDpIA--VaDIQKIIRHL-KERG---IGVLitdHNVRETLGICDraYI--ISEGKVLAEGTPEEI 223
thiQ PRK10771
thiamine ABC transporter ATP-binding protein ThiQ;
31-248 2.66e-25

thiamine ABC transporter ATP-binding protein ThiQ;


Pssm-ID: 182716 [Multi-domain]  Cd Length: 232  Bit Score: 100.04  E-value: 2.66e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  31 SLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWS-SKafaRKVAYLPQQLPPAEGMTVRELVAIG 109
Cdd:PRK10771  19 DLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQDHTTTPpSR---RPVSMLFQENNLFSHLTVAQNIGLG 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 110 RYPwhgALgRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSL 189
Cdd:PRK10771  96 LNP---GL-KLNAAQREKLHAIARQMGIEDLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQEMLTL 171

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 190 VHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMRGETLE-MIYGIP 248
Cdd:PRK10771 172 VSQVCQERQLTLLMVSHSLEDAARIAPRSLVVADGRIAWDGPTDELLSGKASAsALLGIK 231
3a01208 TIGR00958
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
 15-241 3.76e-25

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273363 [Multi-domain]  Cd Length: 711  Bit Score: 104.03  E-value: 3.76e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   15 RNISFRVPGRT---LLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAyLP 91
Cdd:TIGR00958 482 QDVSFSYPNRPdvpVLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGVPLVQYDHHYLHRQVA-LV 560

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   92 QQLPPAEGMTVRELVAIGRypwhgalgrfgaadREKVEEAISLVGLKPLAHRLVDS---------------LSGGERQRA 156
Cdd:TIGR00958 561 GQEPVLFSGSVRENIAYGL--------------TDTPDEEIMAAAKAANAHDFIMEfpngydtevgekgsqLSGGQKQRI 626

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  157 WIAMLVAQDSRCLLLDEPTSALDiahqVDVLSLVHRLSQERGLTVIAVLHDINMAARyCDYLVALRGGEMIAQGTPAEIM 236
Cdd:TIGR00958 627 AIARALVRKPRVLILDEATSALD----AECEQLLQESRSRASRTVLLIAHRLSTVER-ADQILVLKKGSVVEMGTHKQLM 701


                  ....*
gi 536036476  237 RGETL 241
Cdd:TIGR00958 702 EDQGC 706
cbiO PRK13650
energy-coupling factor transporter ATPase;
4-242 4.90e-25

energy-coupling factor transporter ATPase;


Pssm-ID: 184209 [Multi-domain]  Cd Length: 279  Bit Score: 100.19  E-value: 4.90e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   4 YTNHSDTT-FALRNISFRVPgrtllhplsltfpAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKA 82
Cdd:PRK13650  12 FKYKEDQEkYTLNDVSFHVK-------------QGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDLLTEENVWD 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  83 FARKVAYLPQQlPPAE--GMTVRELVAIGrypwhgaLGRFGAAD---REKVEEAISLVGLKPLAHRLVDSLSGGERQRAW 157
Cdd:PRK13650  79 IRHKIGMVFQN-PDNQfvGATVEDDVAFG-------LENKGIPHeemKERVNEALELVGMQDFKEREPARLSGGQKQRVA 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 158 IAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAArYCDYLVALRGGEMIAQGTPAEI-M 236
Cdd:PRK13650 151 IAGAVAMRPKIIILDEATSMLDPEGRLELIKTIKGIRDDYQMTVISITHDLDEVA-LSDRVLVMKNGQVESTSTPRELfS 229


                 ....*.
gi 536036476 237 RGETLE 242
Cdd:PRK13650 230 RGNDLL 235
ABCC_TAP cd03248
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...
 9-226 7.20e-25

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.


Pssm-ID: 213215 [Multi-domain]  Cd Length: 226  Bit Score: 98.70  E-value: 7.20e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   9 DTTFALRNisfrVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVA 88
Cdd:cd03248   16 NVTFAYPT----RPDTLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPISQYEHKYLHSKVS 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  89 YLPQQlPPAEGMTVRELVAIGrypwhgalgrFGAADREKVEEAISlvglKPLAHRLV---------------DSLSGGER 153
Cdd:cd03248   92 LVGQE-PVLFARSLQDNIAYG----------LQSCSFECVKEAAQ----KAHAHSFIselasgydtevgekgSQLSGGQK 156

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 536036476 154 QRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAvlHDINMAARyCDYLVALRGGEM 226
Cdd:cd03248  157 QRVAIARALIRNPQVLILDEATSALDAESEQQVQQALYDWPERRTVLVIA--HRLSTVER-ADQILVLDGGRI 226
ABC_BcrA_bacitracin_resist cd03268
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...
 14-230 9.66e-25

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.


Pssm-ID: 213235 [Multi-domain]  Cd Length: 208  Bit Score: 97.67  E-value: 9.66e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQplESWSSKAFARKVAYLPQQ 93
Cdd:cd03268    3 TNDLTKTYGKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGK--SYQKNIEALRRIGALIEA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  94 lpPA--EGMTVRE-LVAIGRYpwhgaLGRfgaaDREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLL 170
Cdd:cd03268   81 --PGfyPNLTAREnLRLLARL-----LGI----RKKRIDEVLDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNPDLLI 149

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 171 LDEPTSALDIAHQVDVLSLVHRLSQErGLTVIAVLHDINMAARYCDYLVALRGGEMIAQG 230
Cdd:cd03268  150 LDEPTNGLDPDGIKELRELILSLRDQ-GITVLISSHLLSEIQKVADRIGIINKGKLIEEG 208
PRK14246 PRK14246
phosphate ABC transporter ATP-binding protein; Provisional
 3-243 1.56e-24

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172734 [Multi-domain]  Cd Length: 257  Bit Score: 98.58  E-value: 1.56e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   3 EYTNHSDTTFALRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGR------HQPPSEGEILLDAQPLE 76
Cdd:PRK14246   2 EAGKSAEDVFNISRLYLYINDKAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRlieiydSKIKVDGKVLYFGKDIF 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  77 SWSSKAFARKVAYLPQQLPPAEGMTVRELVAigrYPwhgaLGRFGAADREK----VEEAISLVGLKPLAHRLVDS----L 148
Cdd:PRK14246  82 QIDAIKLRKEVGMVFQQPNPFPHLSIYDNIA---YP----LKSHGIKEKREikkiVEECLRKVGLWKEVYDRLNSpasqL 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 149 SGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQErgLTVIAVLHDINMAARYCDYLVALRGGEMIA 228
Cdd:PRK14246 155 SGGQQQRLTIARALALKPKVLLMDEPTSMIDIVNSQAIEKLITELKNE--IAIVIVSHNPQQVARVADYVAFLYNGELVE 232

                        250
                 ....*....|....*
gi 536036476 229 QGTPAEIMRGETLEM 243
Cdd:PRK14246 233 WGSSNEIFTSPKNEL 247
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
 6-237 1.67e-24

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 98.23  E-value: 1.67e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   6 NHSDTTFALRNISFrvpgrtllhplslTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLD---AQPLEswsska 82
Cdd:COG1134   34 TRREEFWALKDVSF-------------EVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRVEVNgrvSALLE------ 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  83 FArkVAYLPQqlppaegMTVRELV-AIGRypwhgALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAML 161
Cdd:COG1134   95 LG--AGFHPE-------LTGRENIyLNGR-----LLGLSRKEIDEKFDEIVEFAELGDFIDQPVKTYSSGMRARLAFAVA 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 536036476 162 VAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLsQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMR 237
Cdd:COG1134  161 TAVDPDILLVDEVLAVGDAAFQKKCLARIREL-RESGRTVIFVSHSMGAVRRLCDRAIWLEKGRLVMDGDPEEVIA 235
ABC_NatA_sodium_exporter cd03266
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...
 30-230 1.70e-24

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.


Pssm-ID: 213233 [Multi-domain]  Cd Length: 218  Bit Score: 97.44  E-value: 1.70e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  30 LSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDA-----QPLESwsskafARKVAYLPQQLPPAEGMTVRE 104
Cdd:cd03266   24 VSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGfdvvkEPAEA------RRRLGFVSDSTGLYDRLTARE 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 105 LVAigrypWHGAL-GRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQ 183
Cdd:cd03266   98 NLE-----YFAGLyGLKGDELTARLEELADRLGMEELLDRRVGGFSTGMRQKVAIARALVHDPPVLLLDEPTTGLDVMAT 172

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 536036476 184 VDVLSLVHRLsQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQG 230
Cdd:cd03266  173 RALREFIRQL-RALGKCILFSTHIMQEVERLCDRVVVLHRGRVVYEG 218
cbiO PRK13649
energy-coupling factor transporter ATPase;
4-235 2.17e-24

energy-coupling factor transporter ATPase;


Pssm-ID: 184208 [Multi-domain]  Cd Length: 280  Bit Score: 98.66  E-value: 2.17e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   4 YTNHSDTTFAlrnisfrvpGRTLLHpLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKA- 82
Cdd:PRK13649  10 YTYQAGTPFE---------GRALFD-VNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLITSTSKNKd 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  83 --FARKVAYLPQQLPPAE--GMTVRELVAIGryPWHgalgrFGAADREKV---EEAISLVGL-KPLAHRLVDSLSGGERQ 154
Cdd:PRK13649  80 ikQIRKKVGLVFQFPESQlfEETVLKDVAFG--PQN-----FGVSQEEAEalaREKLALVGIsESLFEKNPFELSGGQMR 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 155 RAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQErGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAE 234
Cdd:PRK13649 153 RVAIAGILAMEPKILVLDEPTAGLDPKGRKELMTLFKKLHQS-GMTIVLVTHLMDDVANYADFVYVLEKGKLVLSGKPKD 231


                 .
gi 536036476 235 I 235
Cdd:PRK13649 232 I 232
PRK13633 PRK13633
energy-coupling factor transporter ATPase;
30-235 2.77e-24

energy-coupling factor transporter ATPase;


Pssm-ID: 237453 [Multi-domain]  Cd Length: 280  Bit Score: 98.24  E-value: 2.77e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  30 LSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQQLPPAE--GMTVRELVA 107
Cdd:PRK13633  29 VNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGLDTSDEENLWDIRNKAGMVFQNPDNQivATIVEEDVA 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 108 IGryPWHgaLGRFGAADREKVEEAISLVGL---KPLAHRLvdsLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQV 184
Cdd:PRK13633 109 FG--PEN--LGIPPEEIRERVDESLKKVGMyeyRRHAPHL---LSGGQKQRVAIAGILAMRPECIIFDEPTAMLDPSGRR 181

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 536036476 185 DVLSLVHRLSQERGLTVIAVLHDINMAARyCDYLVALRGGEMIAQGTPAEI 235
Cdd:PRK13633 182 EVVNTIKELNKKYGITIILITHYMEEAVE-ADRIIVMDSGKVVMEGTPKEI 231
PRK11160 PRK11160
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 14-236 3.45e-24

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236865 [Multi-domain]  Cd Length: 574  Bit Score: 101.05  E-value: 3.45e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTL--LHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLP 91
Cdd:PRK11160 341 LNNVSFTYPDQPQpvLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGQPIADYSEAALRQAISVVS 420

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  92 QQLPPAEGmTVRELVAIGRypwhgalgrfGAADREKVEEAISLVGL-------KPLAHRLVD---SLSGGERQRAWIAML 161
Cdd:PRK11160 421 QRVHLFSA-TLRDNLLLAA----------PNASDEALIEVLQQVGLeklleddKGLNAWLGEggrQLSGGEQRRLGIARA 489

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 536036476 162 VAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERglTVIAVLHDINMAARYcDYLVALRGGEMIAQGTPAEIM 236
Cdd:PRK11160 490 LLHDAPLLLLDEPTEGLDAETERQILELLAEHAQNK--TVLMITHRLTGLEQF-DRICVMDNGQIIEQGTHQELL 561
potA TIGR01187
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ...
 42-235 4.29e-24

spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 162242 [Multi-domain]  Cd Length: 325  Bit Score: 98.72  E-value: 4.29e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   42 LIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESwsSKAFARKVAYLPQQLPPAEGMTVRELVAIGRypwhgALGRFG 121
Cdd:TIGR01187   1 LLGPSGCGKTTLLRLLAGFEQPDSGSIMLDGEDVTN--VPPHLRHINMVFQSYALFPHMTVEENVAFGL-----KMRKVP 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  122 AADR-EKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLT 200
Cdd:TIGR01187  74 RAEIkPRVLEALRLVQLEEFADRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMQLELKTIQEQLGIT 153

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 536036476  201 VIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEI 235
Cdd:TIGR01187 154 FVFVTHDQEEAMTMSDRIAIMRKGKIAQIGTPEEI 188
YddA COG4178
ABC-type uncharacterized transport system, permease and ATPase components [General function ...
 7-206 6.24e-24

ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];


Pssm-ID: 443337 [Multi-domain]  Cd Length: 571  Bit Score: 100.27  E-value: 6.24e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   7 HSDTTFALRNISFRVP-GRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAqpleswsskafAR 85
Cdd:COG4178  358 SEDGALALEDLTLRTPdGRPLLEDLSLSLKPGERLLITGPSGSGKSTLLRAIAGLWPYGSGRIARPA-----------GA 426

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  86 KVAYLPQQ--LPPAegmTVRELVAigrYPwHGAlgrfGAADREKVEEAISLVGLKPLAHRLVDS------LSGGERQRAW 157
Cdd:COG4178  427 RVLFLPQRpyLPLG---TLREALL---YP-ATA----EAFSDAELREALEAVGLGHLAERLDEEadwdqvLSLGEQQRLA 495

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 536036476 158 IAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRlsQERGLTVIAVLH 206
Cdd:COG4178  496 FARLLLHKPDWLFLDEATSALDEENEAALYQLLRE--ELPGTTVISVGH 542
ssuB PRK11247
aliphatic sulfonates transport ATP-binding subunit; Provisional
 10-225 7.50e-24

aliphatic sulfonates transport ATP-binding subunit; Provisional


Pssm-ID: 183055 [Multi-domain]  Cd Length: 257  Bit Score: 96.67  E-value: 7.50e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  10 TTFALRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESwsskafARKVAY 89
Cdd:PRK11247  11 TPLLLNAVSKRYGERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGELLAGTAPLAE------AREDTR 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  90 LPQQ---LPPAEgmTVRELVAIG-RYPWhgalgrfgaadREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQD 165
Cdd:PRK11247  85 LMFQdarLLPWK--KVIDNVGLGlKGQW-----------RDAALQALAAVGLADRANEWPAALSGGQKQRVALARALIHR 151

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 166 SRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGE 225
Cdd:PRK11247 152 PGLLLLDEPLGALDALTRIEMQDLIESLWQQHGFTVLLVTHDVSEAVAMADRVLLIEEGK 211
PRK10895 PRK10895
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
 11-245 1.00e-23

lipopolysaccharide ABC transporter ATP-binding protein; Provisional


Pssm-ID: 182817 [Multi-domain]  Cd Length: 241  Bit Score: 96.12  E-value: 1.00e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  11 TFALRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARK-VAY 89
Cdd:PRK10895   3 TLTAKNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDISLLPLHARARRgIGY 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  90 LPQQLPPAEGMTVRE-LVAIGRYpwHGALGRFGAADRekVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRC 168
Cdd:PRK10895  83 LPQEASIFRRLSVYDnLMAVLQI--RDDLSAEQREDR--ANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKF 158

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 536036476 169 LLLDEPTSALDIAHQVDVLSLVHRLsQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMRGETLEMIY 245
Cdd:PRK10895 159 ILLDEPFAGVDPISVIDIKRIIEHL-RDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEILQDEHVKRVY 234
PRK10070 PRK10070
proline/glycine betaine ABC transporter ATP-binding protein ProV;
31-236 1.27e-23

proline/glycine betaine ABC transporter ATP-binding protein ProV;


Pssm-ID: 182221 [Multi-domain]  Cd Length: 400  Bit Score: 98.57  E-value: 1.27e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  31 SLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFA----RKVAYLPQQLPPAEGMTVRELV 106
Cdd:PRK10070  48 SLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDAELRevrrKKIAMVFQSFALMPHMTVLDNT 127

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 107 AIGRypwhgALGRFGAADR-EKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVD 185
Cdd:PRK10070 128 AFGM-----ELAGINAEERrEKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPLIRTE 202

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 536036476 186 VLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIM 236
Cdd:PRK10070 203 MQDELVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEIL 253
livG PRK11300
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
 8-235 1.46e-23

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional


Pssm-ID: 183080 [Multi-domain]  Cd Length: 255  Bit Score: 95.83  E-value: 1.46e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   8 SDTTFALRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARK- 86
Cdd:PRK11300   2 SQPLLSVSGLMMRFGGLLAVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIEGLPGHQIARMg 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  87 VAYLPQQLPPAEGMTVRE--LVAIGRYPWHGALG------RFGAADREKVEEA---ISLVGLKPLAHRLVDSLSGGERQR 155
Cdd:PRK11300  82 VVRTFQHVRLFREMTVIEnlLVAQHQQLKTGLFSgllktpAFRRAESEALDRAatwLERVGLLEHANRQAGNLAYGQQRR 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 156 AWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEI 235
Cdd:PRK11300 162 LEIARCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNEHNVTVLLIEHDMKLVMGISDRIYVVNQGTPLANGTPEEI 241
cbiO PRK13645
energy-coupling factor transporter ATPase;
14-241 1.67e-23

energy-coupling factor transporter ATPase;


Pssm-ID: 184204 [Multi-domain]  Cd Length: 289  Bit Score: 96.62  E-value: 1.67e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRT-----LLHPLSLTFPAGKVTGLIGHNGSGKSTLLKM-------------LGRHQPPSEGEILLDAQPL 75
Cdd:PRK13645   9 LDNVSYTYAKKTpfefkALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLtngliisetgqtiVGDYAIPANLKKIKEVKRL 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  76 eswsskafaRKVAYLPQQLPPAEGM--TVRELVAIGryPWHgaLGRFGAADREKVEEAISLVGL-KPLAHRLVDSLSGGE 152
Cdd:PRK13645  89 ---------RKEIGLVFQFPEYQLFqeTIEKDIAFG--PVN--LGENKQEAYKKVPELLKLVQLpEDYVKRSPFELSGGQ 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 153 RQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTP 232
Cdd:PRK13645 156 KRRVALAGIIAMDGNTLVLDEPTGGLDPKGEEDFINLFERLNKEYKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGSP 235


                 ....*....
gi 536036476 233 AEIMRGETL 241
Cdd:PRK13645 236 FEIFSNQEL 244
PRK11831 PRK11831
phospholipid ABC transporter ATP-binding protein MlaF;
14-257 1.90e-23

phospholipid ABC transporter ATP-binding protein MlaF;


Pssm-ID: 236997 [Multi-domain]  Cd Length: 269  Bit Score: 95.99  E-value: 1.90e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWS-SKAFA--RKVAYL 90
Cdd:PRK11831  10 MRGVSFTRGNRCIFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENIPAMSrSRLYTvrKRMSML 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  91 PQQLPPAEGMTVRELVAigrYPW--HGALGRfgAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRC 168
Cdd:PRK11831  90 FQSGALFTDMNVFDNVA---YPLreHTQLPA--PLLHSTVMMKLEAVGLRGAAKLMPSELSGGMARRAALARAIALEPDL 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 169 LLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMRGE---TLEMIY 245
Cdd:PRK11831 165 IMFDEPFVGQDPITMGVLVKLISELNSALGVTCVVVSHDVPEVLSIADHAYIVADKKIVAHGSAQALQANPdprVRQFLD 244

                        250
                 ....*....|....
gi 536036476 246 GIPMGILP--HPAG 257
Cdd:PRK11831 245 GIADGPVPfrYPAG 258
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 37-210 3.25e-23

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 98.32  E-value: 3.25e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  37 GKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAqpleswsskafarKVAYLPQQLPPAEGMTVRELVaigrypwHGA 116
Cdd:COG1245  366 GEVLGIVGPNGIGKTTFAKILAGVLKPDEGEVDEDL-------------KISYKPQYISPDYDGTVEEFL-------RSA 425

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 117 LGRFGAADREKVEEAISLvGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQE 196
Cdd:COG1245  426 NTDDFGSSYYKTEIIKPL-GLEKLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRFAEN 504

                        170
                 ....*....|....
gi 536036476 197 RGLTVIAVLHDINM 210
Cdd:COG1245  505 RGKTAMVVDHDIYL 518
SufC COG0396
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ...
 14-232 3.69e-23

Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440165 [Multi-domain]  Cd Length: 245  Bit Score: 94.36  E-value: 3.69e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKML-GR-HQPPSEGEILLDAQPLESWSSKAFARKVAYLP 91
Cdd:COG0396    3 IKNLHVSVEGKEILKGVNLTIKPGEVHAIMGPNGSGKSTLAKVLmGHpKYEVTSGSILLDGEDILELSPDERARAGIFLA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  92 QQLPPA-EGMTVRELV-----AIGRYPWHgalgrfGAADREKVEEAISLVGLKP-LAHRLVD-SLSGGERQRAWIAMLVA 163
Cdd:COG0396   83 FQYPVEiPGVSVSNFLrtalnARRGEELS------AREFLKLLKEKMKELGLDEdFLDRYVNeGFSGGEKKRNEILQMLL 156

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 536036476 164 QDSRCLLLDEPTSALDIahqvDVLSLVHR-----LSQERGLTVIA----VLHDINmaaryCDYLVALRGGEMIAQGTP 232
Cdd:COG0396  157 LEPKLAILDETDSGLDI----DALRIVAEgvnklRSPDRGILIIThyqrILDYIK-----PDFVHVLVDGRIVKSGGK 225
PRK14247 PRK14247
phosphate ABC transporter ATP-binding protein; Provisional
 14-235 6.33e-23

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172735 [Multi-domain]  Cd Length: 250  Bit Score: 94.21  E-value: 6.33e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGR-----HQPPSEGEILLDAQPLESWSSKAFARKVA 88
Cdd:PRK14247   6 IRDLKVSFGQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRlielyPEARVSGEVYLDGQDIFKMDVIELRRRVQ 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  89 YLPQQLPPAEGMTVRELVAIGRypwhgALGRFGAADRE---KVEEAISLVGL-KPLAHRL---VDSLSGGERQRAWIAML 161
Cdd:PRK14247  86 MVFQIPNPIPNLSIFENVALGL-----KLNRLVKSKKElqeRVRWALEKAQLwDEVKDRLdapAGKLSGGQQQRLCIARA 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 536036476 162 VAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQErgLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEI 235
Cdd:PRK14247 161 LAFQPEVLLADEPTANLDPENTAKIESLFLELKKD--MTIVLVTHFPQQAARISDYVAFLYKGQIVEWGPTREV 232
PRK13536 PRK13536
nodulation factor ABC transporter ATP-binding protein NodI;
6-236 6.52e-23

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237419 [Multi-domain]  Cd Length: 340  Bit Score: 95.67  E-value: 6.52e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   6 NHSDTTFALRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFAR 85
Cdd:PRK13536  36 SMSTVAIDLAGVSKSYGDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGVPVPARARLARAR 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  86 kVAYLPQQLPPAEGMTVRE-LVAIGRYpwhgalgrFGAADREkVEEAI-SLVGLKPL---AHRLVDSLSGGERQRAWIAM 160
Cdd:PRK13536 116 -IGVVPQFDNLDLEFTVREnLLVFGRY--------FGMSTRE-IEAVIpSLLEFARLeskADARVSDLSGGMKRRLTLAR 185

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 536036476 161 LVAQDSRCLLLDEPTSALDiAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIM 236
Cdd:PRK13536 186 ALINDPQLLILDEPTTGLD-PHARHLIWERLRSLLARGKTILLTTHFMEEAERLCDRLCVLEAGRKIAEGRPHALI 260
cbiO PRK13644
energy-coupling factor transporter ATPase;
14-242 6.58e-23

energy-coupling factor transporter ATPase;


Pssm-ID: 106587 [Multi-domain]  Cd Length: 274  Bit Score: 94.67  E-value: 6.58e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVP-GRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQ 92
Cdd:PRK13644   4 LENVSYSYPdGTPALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGIDTGDFSKLQGIRKLVGIVF 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  93 QLPPAE--GMTVRELVAIGryPWHGALGRFGAadREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLL 170
Cdd:PRK13644  84 QNPETQfvGRTVEEDLAFG--PENLCLPPIEI--RKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVALAGILTMEPECLI 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 536036476 171 LDEPTSALDIAHQVDVLSLVHRLsQERGLTVIAVLHDINmAARYCDYLVALRGGEMIAQGTPAEIMRGETLE 242
Cdd:PRK13644 160 FDEVTSMLDPDSGIAVLERIKKL-HEKGKTIVYITHNLE-ELHDADRIIVMDRGKIVLEGEPENVLSDVSLQ 229
PhnL COG4778
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...
 23-224 8.80e-23

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];


Pssm-ID: 443809 [Multi-domain]  Cd Length: 229  Bit Score: 93.27  E-value: 8.80e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  23 GRTL--LHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQplESWS--SKAFARKVAYLPQQ----- 93
Cdd:COG4778   21 GKRLpvLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVRHD--GGWVdlAQASPREILALRRRtigyv 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  94 ------LP--PAegmtvRELVAigrypwhGALGRFGAAD---REKVEEAISLVGLKPlahRLVDS----LSGGERQRAWI 158
Cdd:COG4778   99 sqflrvIPrvSA-----LDVVA-------EPLLERGVDReeaRARARELLARLNLPE---RLWDLppatFSGGEQQRVNI 163

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 536036476 159 AMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLsQERGLTVIAVLHDINMAARYCDYLVALRGG 224
Cdd:COG4778  164 ARGFIADPPLLLLDEPTASLDAANRAVVVELIEEA-KARGTAIIGIFHDEEVREAVADRVVDVTPF 228
ABC_RNaseL_inhibitor_domain1 cd03236
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 37-218 9.02e-23

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213203 [Multi-domain]  Cd Length: 255  Bit Score: 93.59  E-value: 9.02e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  37 GKVTGLIGHNGSGKSTLLKML--------GRHQ-PPSEGEILLDAQPLESwsSKAFAR------KVAYLPQ---QLPPAE 98
Cdd:cd03236   26 GQVLGLVGPNGIGKSTALKILagklkpnlGKFDdPPDWDEILDEFRGSEL--QNYFTKllegdvKVIVKPQyvdLIPKAV 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  99 GMTVRELVAigrypwhgalgrfGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSAL 178
Cdd:cd03236  104 KGKVGELLK-------------KKDERGKLDELVDQLELRHVLDRNIDQLSGGELQRVAIAAALARDADFYFFDEPSSYL 170

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 536036476 179 DIAHQVDVLSLVHRLSQErGLTVIAVLHDINMaaryCDYL 218
Cdd:cd03236  171 DIKQRLNAARLIRELAED-DNYVLVVEHDLAV----LDYL 205
cbiO PRK13643
energy-coupling factor transporter ATPase;
4-237 9.14e-23

energy-coupling factor transporter ATPase;


Pssm-ID: 184203 [Multi-domain]  Cd Length: 288  Bit Score: 94.42  E-value: 9.14e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   4 YTNHSDTTFALRnisfrvpgrtLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAF 83
Cdd:PRK13643   9 YTYQPNSPFASR----------ALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVGDIVVSSTSKQKE 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  84 ---ARKVAYLPQQLPPAEGM--TVRELVAIGryPWHGALGRfgaADREKVE-EAISLVGL-KPLAHRLVDSLSGGERQRA 156
Cdd:PRK13643  79 ikpVRKKVGVVFQFPESQLFeeTVLKDVAFG--PQNFGIPK---EKAEKIAaEKLEMVGLaDEFWEKSPFELSGGQMRRV 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 157 WIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQErGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIM 236
Cdd:PRK13643 154 AIAGILAMEPEVLVLDEPTAGLDPKARIEMMQLFESIHQS-GQTVVLVTHLMDDVADYADYVYLLEKGHIISCGTPSDVF 232


                 .
gi 536036476 237 R 237
Cdd:PRK13643 233 Q 233
lolD PRK11629
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
26-213 9.20e-23

lipoprotein-releasing ABC transporter ATP-binding protein LolD;


Pssm-ID: 183244 [Multi-domain]  Cd Length: 233  Bit Score: 93.34  E-value: 9.20e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  26 LLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFA----RKVAYLPQ--QLPPaeG 99
Cdd:PRK11629  24 VLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAAKAelrnQKLGFIYQfhHLLP--D 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 100 MTVRELVA----IGrypwhgalGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPT 175
Cdd:PRK11629 102 FTALENVAmpllIG--------KKKPAEINSRALEMLAAVGLEHRANHRPSELSGGERQRVAIARALVNNPRLVLADEPT 173

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 536036476 176 SALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAAR 213
Cdd:PRK11629 174 GNLDARNADSIFQLLGELNRLQGTAFLVVTHDLQLAKR 211
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
14-239 1.08e-22

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 94.49  E-value: 1.08e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARkVAYLPQ- 92
Cdd:PRK13537  10 FRNVEKRYGDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVPSRARHARQR-VGVVPQf 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  93 -QLPPaeGMTVRE-LVAIGRYpwhgaLGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLL 170
Cdd:PRK13537  89 dNLDP--DFTVREnLLVFGRY-----FGLSAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDVLV 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 536036476 171 LDEPTSALDiaHQVDVLsLVHRLSQ--ERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMRGE 239
Cdd:PRK13537 162 LDEPTTGLD--PQARHL-MWERLRSllARGKTILLTTHFMEEAERLCDRLCVIEEGRKIAEGAPHALIESE 229
nikD PRK10418
nickel transporter ATP-binding protein NikD; Provisional
 11-237 1.21e-22

nickel transporter ATP-binding protein NikD; Provisional


Pssm-ID: 236688 [Multi-domain]  Cd Length: 254  Bit Score: 93.23  E-value: 1.21e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  11 TFALRNISFRVPgRTLLHPLSLTFPAGKVTGLIGHNGSGKS-TLLKMLGRhQPP----SEGEILLDAQPLESWSSKAfaR 85
Cdd:PRK10418   4 QIELRNIALQAA-QPLVHGVSLTLQRGRVLALVGGSGSGKSlTCAAALGI-LPAgvrqTAGRVLLDGKPVAPCALRG--R 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  86 KVAYLPQQlPPAEGMTVRELVAIGRYPWHgALGRfgAADREKVEEAISLVGLkPLAHRLVDS----LSGGERQRAWIAML 161
Cdd:PRK10418  80 KIATIMQN-PRSAFNPLHTMHTHARETCL-ALGK--PADDATLTAALEAVGL-ENAARVLKLypfeMSGGMLQRMMIALA 154

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 536036476 162 VAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMR 237
Cdd:PRK10418 155 LLCEAPFIIADEPTTDLDVVAQARILDLLESIVQKRALGMLLVTHDMGVVARLADDVAVMSHGRIVEQGDVETLFN 230
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
37-210 1.23e-22

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 96.80  E-value: 1.23e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  37 GKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAqpleswsskafarKVAYLPQQLPPAEGMTVRELVAigrypwhGA 116
Cdd:PRK13409 365 GEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEVDPEL-------------KISYKPQYIKPDYDGTVEDLLR-------SI 424

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 117 LGRFGAADREkvEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQE 196
Cdd:PRK13409 425 TDDLGSSYYK--SEIIKPLQLERLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRIAEE 502

                        170
                 ....*....|....
gi 536036476 197 RGLTVIAVLHDINM 210
Cdd:PRK13409 503 REATALVVDHDIYM 516
ABC_CcmA_heme_exporter cd03231
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...
 23-211 1.48e-22

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.


Pssm-ID: 213198 [Multi-domain]  Cd Length: 201  Bit Score: 91.79  E-value: 1.48e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  23 GRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESwSSKAFARKVAYLPQQLPPAEGMTV 102
Cdd:cd03231   12 GRALFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLDF-QRDSIARGLLYLGHAPGIKTTLSV 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 103 RELVaigrypwhgalgRFGAAD--REKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDI 180
Cdd:cd03231   91 LENL------------RFWHADhsDEQVEEALARVGLNGFEDRPVAQLSAGQQRRVALARLLLSGRPLWILDEPTTALDK 158

                        170       180       190
                 ....*....|....*....|....*....|.
gi 536036476 181 AHQVDVLSLVHRLSQERGLTVIAVLHDINMA 211
Cdd:cd03231  159 AGVARFAEAMAGHCARGGMVVLTTHQDLGLS 189
tauB PRK11248
taurine ABC transporter ATP-binding subunit;
14-211 1.63e-22

taurine ABC transporter ATP-binding subunit;


Pssm-ID: 183056 [Multi-domain]  Cd Length: 255  Bit Score: 93.23  E-value: 1.63e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKafaRKVAYLPQQ 93
Cdd:PRK11248   4 ISHLYADYGGKPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPVEGPGAE---RGVVFQNEG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  94 LPPAEgmTVRELVAIGRypwhgALGRFGAADREKV-EEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLD 172
Cdd:PRK11248  81 LLPWR--NVQDNVAFGL-----QLAGVEKMQRLEIaHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLD 153

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 536036476 173 EPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMA 211
Cdd:PRK11248 154 EPFGALDAFTREQMQTLLLKLWQETGKQVLLITHDIEEA 192
bacteriocin_ABC TIGR01193
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ...
 4-231 1.91e-22

ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]


Pssm-ID: 130261 [Multi-domain]  Cd Length: 708  Bit Score: 96.35  E-value: 1.91e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476    4 YTNHSDTTFALRNISFRVP-GRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKA 82
Cdd:TIGR01193 466 ELNNLNGDIVINDVSYSYGyGSNILSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGEILLNGFSLKDIDRHT 545

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   83 FARKVAYLPQQlPPAEGMTVRELVAIGRYPwhgalgrfgAADREKVEEAISLVGLK------PLAH--RLVD---SLSGG 151
Cdd:TIGR01193 546 LRQFINYLPQE-PYIFSGSILENLLLGAKE---------NVSQDEIWAACEIAEIKddienmPLGYqtELSEegsSISGG 615

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  152 ERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQErglTVIAVLHDINMAARyCDYLVALRGGEMIAQGT 231
Cdd:TIGR01193 616 QKQRIALARALLTDSKVLILDESTSNLDTITEKKIVNNLLNLQDK---TIIFVAHRLSVAKQ-SDKIIVLDHGKIIEQGS 691
ABCF_EF-3 cd03221
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...
 14-225 1.96e-22

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.


Pssm-ID: 213188 [Multi-domain]  Cd Length: 144  Bit Score: 89.82  E-value: 1.96e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEIlldaqpleSWSSKAfarKVAYLPQq 93
Cdd:cd03221    3 LENLSKTYGGKLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIV--------TWGSTV---KIGYFEQ- 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  94 lppaegmtvrelvaigrypwhgalgrfgaadrekveeaislvglkplahrlvdsLSGGERQRAWIAMLVAQDSRCLLLDE 173
Cdd:cd03221   71 ------------------------------------------------------LSGGEKMRLALAKLLLENPNLLLLDE 96

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 536036476 174 PTSALDIAHqvdVLSLVHRLSQERGlTVIAVLHDINMAARYCDYLVALRGGE 225
Cdd:cd03221   97 PTNHLDLES---IEALEEALKEYPG-TVILVSHDRYFLDQVATKIIELEDGK 144
cbiO PRK13642
energy-coupling factor transporter ATPase;
27-235 1.99e-22

energy-coupling factor transporter ATPase;


Pssm-ID: 184202 [Multi-domain]  Cd Length: 277  Bit Score: 93.23  E-value: 1.99e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  27 LHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQQlPPAE--GMTVRE 104
Cdd:PRK13642  23 LNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELLTAENVWNLRRKIGMVFQN-PDNQfvGATVED 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 105 LVAIGrypwhgaLGRFGAADRE---KVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIA 181
Cdd:PRK13642 102 DVAFG-------MENQGIPREEmikRVDEALLAVNMLDFKTREPARLSGGQKQRVAVAGIIALRPEIIILDESTSMLDPT 174

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 536036476 182 HQVDVLSLVHRLSQERGLTVIAVLHDINMAARyCDYLVALRGGEMIAQGTPAEI 235
Cdd:PRK13642 175 GRQEIMRVIHEIKEKYQLTVLSITHDLDEAAS-SDRILVMKAGEIIKEAAPSEL 227
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 37-218 2.41e-22

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 96.01  E-value: 2.41e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  37 GKVTGLIGHNGSGKSTLLKML--------GRHQ-PPSEGEILldaqpleswssKAFAR---------------KVAYLPQ 92
Cdd:COG1245   99 GKVTGILGPNGIGKSTALKILsgelkpnlGDYDeEPSWDEVL-----------KRFRGtelqdyfkklangeiKVAHKPQ 167

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  93 ---QLPPAEGMTVRELVAigrypwhgalgrfGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCL 169
Cdd:COG1245  168 yvdLIPKVFKGTVRELLE-------------KVDERGKLDELAEKLGLENILDRDISELSGGELQRVAIAAALLRDADFY 234

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 536036476 170 LLDEPTSALDIAHQVDVLSLVHRLSQErGLTVIAVLHDINMaaryCDYL 218
Cdd:COG1245  235 FFDEPSSYLDIYQRLNVARLIRELAEE-GKYVLVVEHDLAI----LDYL 278
PRK10851 PRK10851
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
23-237 2.80e-22

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;


Pssm-ID: 182778 [Multi-domain]  Cd Length: 353  Bit Score: 94.00  E-value: 2.80e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  23 GRT-LLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAfaRKVAYLPQQLPPAEGMT 101
Cdd:PRK10851  13 GRTqVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSRLHARD--RKVGFVFQHYALFRHMT 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 102 VRELVAIGR--YPWHGALGRfgAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALD 179
Cdd:PRK10851  91 VFDNIAFGLtvLPRRERPNA--AAIKAKVTQLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVEPQILLLDEPFGALD 168

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 536036476 180 IAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMR 237
Cdd:PRK10851 169 AQVRKELRRWLRQLHEELKFTSVFVTHDQEEAMEVADRVVVMSQGNIEQAGTPDQVWR 226
ABCC_cytochrome_bd cd03247
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...
 12-230 3.38e-22

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.


Pssm-ID: 213214 [Multi-domain]  Cd Length: 178  Bit Score: 90.45  E-value: 3.38e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  12 FALRNISFRVPG--RTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWsSKAFARKVAY 89
Cdd:cd03247    1 LSINNVSFSYPEqeQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVPVSDL-EKALSSLISV 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  90 LPQQlPPAEGMTVRElvaigrypwhgALGRfgaadrekveeaislvglkplahrlvdSLSGGERQRAWIAMLVAQDSRCL 169
Cdd:cd03247   80 LNQR-PYLFDTTLRN-----------NLGR---------------------------RFSGGERQRLALARILLQDAPIV 120

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 536036476 170 LLDEPTSALDIAHQVDVLSLVhrLSQERGLTVIAVLHDInMAARYCDYLVALRGGEMIAQG 230
Cdd:cd03247  121 LLDEPTVGLDPITERQLLSLI--FEVLKDKTLIWITHHL-TGIEHMDKILFLENGKIIMQG 178
ATM1 COG5265
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ...
 15-237 4.65e-22

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444078 [Multi-domain]  Cd Length: 605  Bit Score: 94.89  E-value: 4.65e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  15 RNISFRV-PGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQQ 93
Cdd:COG5265  361 ENVSFGYdPERPILKGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILIDGQDIRDVTQASLRAAIGIVPQD 440

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  94 lppaegmTV------RELVAIGRyPwhgalgrfgAADREKVEEAISLVGLkplaHRLVDS---------------LSGGE 152
Cdd:COG5265  441 -------TVlfndtiAYNIAYGR-P---------DASEEEVEAAARAAQI----HDFIESlpdgydtrvgerglkLSGGE 499

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 153 RQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERglTVIAVLHDINMAARyCDYLVALRGGEMIAQGTP 232
Cdd:COG5265  500 KQRVAIARTLLKNPPILIFDEATSALDSRTERAIQAALREVARGR--TTLVIAHRLSTIVD-ADEILVLEAGRIVERGTH 576


                 ....*
gi 536036476 233 AEIMR 237
Cdd:COG5265  577 AELLA 581
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 22-214 5.28e-22

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 94.62  E-value: 5.28e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   22 PGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLK-MLGRHQpPSEGEILldAQPleswsskafARKVAYLPQ--QLPPAE 98
Cdd:TIGR03719  16 PKKEILKDISLSFFPGAKIGVLGLNGAGKSTLLRiMAGVDK-DFNGEAR--PQP---------GIKVGYLPQepQLDPTK 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   99 gmTVRELVAIGRYPWHGALGRFG----------------AADREKVEEAISLVGLKPLAHRL---------------VDS 147
Cdd:TIGR03719  84 --TVRENVEEGVAEIKDALDRFNeisakyaepdadfdklAAEQAELQEIIDAADAWDLDSQLeiamdalrcppwdadVTK 161

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 536036476  148 LSGGERQRAWIAMLVAQDSRCLLLDEPTSALDiAHQVDVLSlvHRLSQERGlTVIAVLHDinmaaRY 214
Cdd:TIGR03719 162 LSGGERRRVALCRLLLSKPDMLLLDEPTNHLD-AESVAWLE--RHLQEYPG-TVVAVTHD-----RY 219
PRK13539 PRK13539
cytochrome c biogenesis protein CcmA; Provisional
 23-206 5.60e-22

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 237421 [Multi-domain]  Cd Length: 207  Bit Score: 90.32  E-value: 5.60e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  23 GRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESwsSKAFARkVAYLPQQ--LPPAegM 100
Cdd:PRK13539  14 GRVLFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDIDD--PDVAEA-CHYLGHRnaMKPA--L 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 101 TVRELVAIgrypWHGALGrfgaADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDI 180
Cdd:PRK13539  89 TVAENLEF----WAAFLG----GEELDIAAALEAVGLAPLAHLPFGYLSAGQKRRVALARLLVSNRPIWILDEPTAALDA 160

                        170       180
                 ....*....|....*....|....*...
gi 536036476 181 AHQVDVLSLV--HRlsqERGLTVIAVLH 206
Cdd:PRK13539 161 AAVALFAELIraHL---AQGGIVIAATH 185
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
 14-257 5.61e-22

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 94.61  E-value: 5.61e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPS--EGEILLDAQPLESWSSKAFARK-VAYL 90
Cdd:PRK13549   8 MKNITKTFGGVKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGVYPHGtyEGEIIFEGEELQASNIRDTERAgIAII 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  91 PQQLPPAEGMTVRELVAIGRYPWHGALGRFGAADREkVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLL 170
Cdd:PRK13549  88 HQELALVKELSVLENIFLGNEITPGGIMDYDAMYLR-AQKLLAQLKLDINPATPVGNLGLGQQQLVEIAKALNKQARLLI 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 171 LDEPTSALDIAHQVDVLSLVHRLsQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMRGETLEMIYGIPMG 250
Cdd:PRK13549 167 LDEPTASLTESETAVLLDIIRDL-KAHGIACIYISHKLNEVKAISDTICVIRDGRHIGTRPAAGMTEDDIITMMVGRELT 245

                        250
                 ....*....|.
gi 536036476 251 IL----PHPAG 257
Cdd:PRK13549 246 ALyprePHTIG 256
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
37-258 8.79e-22

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 94.10  E-value: 8.79e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  37 GKVTGLIGHNGSGKSTLLKML--------GRHQ-PPSEGEILldaqpleswssKAFAR---------------KVAYLPQ 92
Cdd:PRK13409  99 GKVTGILGPNGIGKTTAVKILsgelipnlGDYEeEPSWDEVL-----------KRFRGtelqnyfkklyngeiKVVHKPQ 167

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  93 ---QLPPAEGMTVRELVAigrypwhgalgrfGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCL 169
Cdd:PRK13409 168 yvdLIPKVFKGKVRELLK-------------KVDERGKLDEVVERLGLENILDRDISELSGGELQRVAIAAALLRDADFY 234

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 170 LLDEPTSALDIAHQVDVLSLVHRLSQERglTVIAVLHDINMaaryCDYLValrggemiaqgtpaeimrgETLEMIYGIP- 248
Cdd:PRK13409 235 FFDEPTSYLDIRQRLNVARLIRELAEGK--YVLVVEHDLAV----LDYLA-------------------DNVHIAYGEPg 289

                        250
                 ....*....|.
gi 536036476 249 -MGILPHPAGA 258
Cdd:PRK13409 290 aYGVVSKPKGV 300
ccmA TIGR01189
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...
 13-211 9.15e-22

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]


Pssm-ID: 273491 [Multi-domain]  Cd Length: 198  Bit Score: 89.73  E-value: 9.15e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   13 ALRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLeSWSSKAFARKVAYLPQ 92
Cdd:TIGR01189   2 AARNLACSRGERMLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPL-AEQRDEPHENILYLGH 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   93 QLPPAEGMTVRELVAIgrypWHgalgRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLD 172
Cdd:TIGR01189  81 LPGLKPELSALENLHF----WA----AIHGGAQRTIEDALAAVGLTGFEDLPAAQLSAGQQRRLALARLWLSRRPLWILD 152

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 536036476  173 EPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMA 211
Cdd:TIGR01189 153 EPTTALDKAGVALLAGLLRAHLARGGIVLLTTHQDLGLV 191
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
9-237 1.20e-21

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 93.54  E-value: 1.20e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   9 DTTFALRNISfrvpGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKML-GRHqPPSEGEILLDAQPLESWS-SKAFARK 86
Cdd:COG1129  254 EVVLEVEGLS----VGGVVRDVSFSVRAGEILGIAGLVGAGRTELARALfGAD-PADSGEIRLDGKPVRIRSpRDAIRAG 328

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  87 VAYLPqqlppaE---------GMTVRE---LVAIGRYPWHGALGRfgAADREKVEEAISLVGLK-PLAHRLVDSLSGGER 153
Cdd:COG1129  329 IAYVP------EdrkgeglvlDLSIREnitLASLDRLSRGGLLDR--RRERALAEEYIKRLRIKtPSPEQPVGNLSGGNQ 400

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 154 QRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQErGLTVIAVLHDINMAARYCDYLVALRGGEMIA----- 228
Cdd:COG1129  401 QKVVLAKWLATDPKVLILDEPTRGIDVGAKAEIYRLIRELAAE-GKAVIVISSELPELLGLSDRILVMREGRIVGeldre 479


                 ....*....
gi 536036476 229 QGTPAEIMR 237
Cdd:COG1129  480 EATEEAIMA 488
ArtP COG4161
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
14-231 1.96e-21

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443326 [Multi-domain]  Cd Length: 242  Bit Score: 89.69  E-value: 1.96e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLD------AQPLESWSSKAFARKV 87
Cdd:COG4161    5 LKNINCFYGSHQALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAghqfdfSQKPSEKAIRLLRQKV 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  88 AYLPQQ--LPPAegMTVRE--LVAIGRypwhgALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVA 163
Cdd:COG4161   85 GMVFQQynLWPH--LTVMEnlIEAPCK-----VLGLSKEQAREKAMKLLARLRLTDKADRFPLHLSGGQQQRVAIARALM 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 164 QDSRCLLLDEPTSALD--IAHQvdVLSLVHRLSQErGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGT 231
Cdd:COG4161  158 MEPQVLLFDEPTAALDpeITAQ--VVEIIRELSQT-GITQVIVTHEVEFARKVASQVVYMEKGRIIEQGD 224
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
14-246 2.15e-21

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 92.93  E-value: 2.15e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSK-AFARKVAYLPQ 92
Cdd:PRK09700   8 MAGIGKSFGPVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNKLDHKlAAQLGIGIIYQ 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  93 QLPPAEGMTVRELVAIGRYPWHGALGrFGAAD----REKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRC 168
Cdd:PRK09700  88 ELSVIDELTVLENLYIGRHLTKKVCG-VNIIDwremRVRAAMMLLRVGLKVDLDEKVANLSISHKQMLEIAKTLMLDAKV 166

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 536036476 169 LLLDEPTSALDIAhQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMRGETLEMIYG 246
Cdd:PRK09700 167 IIMDEPTSSLTNK-EVDYLFLIMNQLRKEGTAIVYISHKLAEIRRICDRYTVMKDGSSVCSGMVSDVSNDDIVRLMVG 243
PRK10790 PRK10790
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
9-206 2.31e-21

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;


Pssm-ID: 182733 [Multi-domain]  Cd Length: 592  Bit Score: 92.86  E-value: 2.31e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   9 DTTFALRNisfrvpGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVA 88
Cdd:PRK10790 345 NVSFAYRD------DNLVLQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSSLSHSVLRQGVA 418

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  89 yLPQQLPPAEGMTVRELVAIGRypwhgalgrfgAADREKVEEAISLVGLKPLAHRLVD-----------SLSGGERQRAW 157
Cdd:PRK10790 419 -MVQQDPVVLADTFLANVTLGR-----------DISEEQVWQALETVQLAELARSLPDglytplgeqgnNLSVGQKQLLA 486

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 536036476 158 IAMLVAQDSRCLLLDEPTSALD-------------IAHQVDVLSLVHRLSQERGLTVIAVLH 206
Cdd:PRK10790 487 LARVLVQTPQILILDEATANIDsgteqaiqqalaaVREHTTLVVIAHRLSTIVEADTILVLH 548
fbpC PRK11432
ferric ABC transporter ATP-binding protein;
14-237 2.93e-21

ferric ABC transporter ATP-binding protein;


Pssm-ID: 183133 [Multi-domain]  Cd Length: 351  Bit Score: 91.32  E-value: 2.93e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAfaRKVAYLPQQ 93
Cdd:PRK11432   9 LKNITKRFGSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDVTHRSIQQ--RDICMVFQS 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  94 LPPAEGMTVRELVAIGRypwhGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDE 173
Cdd:PRK11432  87 YALFPHMSLGENVGYGL----KMLGVPKEERKQRVKEALELVDLAGFEDRYVDQISGGQQQRVALARALILKPKVLLFDE 162

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 536036476 174 PTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMR 237
Cdd:PRK11432 163 PLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSPQELYR 226
PRK11176 PRK11176
lipid A ABC transporter ATP-binding protein/permease MsbA;
15-236 3.54e-21

lipid A ABC transporter ATP-binding protein/permease MsbA;


Pssm-ID: 183016 [Multi-domain]  Cd Length: 582  Bit Score: 92.39  E-value: 3.54e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  15 RNISFRVPGRTL--LHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQ 92
Cdd:PRK11176 345 RNVTFTYPGKEVpaLRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGHDLRDYTLASLRNQVALVSQ 424

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  93 QLppaegMTVRELVA--IgrypwhgALGRFGAADREKVEEAISLVG----LKPLAHRLvD--------SLSGGERQRAWI 158
Cdd:PRK11176 425 NV-----HLFNDTIAnnI-------AYARTEQYSREQIEEAARMAYamdfINKMDNGL-DtvigengvLLSGGQRQRIAI 491

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 536036476 159 AMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIA-VLHDINMAarycDYLVALRGGEMIAQGTPAEIM 236
Cdd:PRK11176 492 ARALLRDSPILILDEATSALDTESERAIQAALDELQKNRTSLVIAhRLSTIEKA----DEILVVEDGEIVERGTHAELL 566
ABC_KpsT_Wzt cd03220
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...
 13-230 6.65e-21

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.


Pssm-ID: 213187 [Multi-domain]  Cd Length: 224  Bit Score: 87.97  E-value: 6.65e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  13 ALRNISFrvpgrtllhplslTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDaqpleswsskafaRKVAYLpq 92
Cdd:cd03220   37 ALKDVSF-------------EVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVTVR-------------GRVSSL-- 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  93 qLPPAEGM----TVRE-LVAIGRYpwhgaLGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSR 167
Cdd:cd03220   89 -LGLGGGFnpelTGREnIYLNGRL-----LGLSRKEIDEKIDEIIEFSELGDFIDLPVKTYSSGMKARLAFAIATALEPD 162

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 536036476 168 CLLLDEPTSALDIAHQVDVLSLVHRLsQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQG 230
Cdd:cd03220  163 ILLIDEVLAVGDAAFQEKCQRRLREL-LKQGKTVILVSHDPSSIKRLCDRALVLEKGKIRFDG 224
cbiO PRK13641
energy-coupling factor transporter ATPase;
22-235 1.54e-20

energy-coupling factor transporter ATPase;


Pssm-ID: 237456 [Multi-domain]  Cd Length: 287  Bit Score: 88.35  E-value: 1.54e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  22 PGRTL----LHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSS----KAFARKVAyLPQQ 93
Cdd:PRK13641  14 PGTPMekkgLDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHITPETGnknlKKLRKKVS-LVFQ 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  94 LPPAEGM--TVRELVAIGryPWHgalgrFGAADREKVEEA---ISLVGLKP-LAHRLVDSLSGGERQRAWIAMLVAQDSR 167
Cdd:PRK13641  93 FPEAQLFenTVLKDVEFG--PKN-----FGFSEDEAKEKAlkwLKKVGLSEdLISKSPFELSGGQMRRVAIAGVMAYEPE 165

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 536036476 168 CLLLDEPTSALDIAHQVDVLSLVHRLsQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEI 235
Cdd:PRK13641 166 ILCLDEPAAGLDPEGRKEMMQLFKDY-QKAGHTVILVTHNMDDVAEYADDVLVLEHGKLIKHASPKEI 232
PRK10619 PRK10619
histidine ABC transporter ATP-binding protein HisP;
26-236 2.23e-20

histidine ABC transporter ATP-binding protein HisP;


Pssm-ID: 182592 [Multi-domain]  Cd Length: 257  Bit Score: 87.33  E-value: 2.23e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  26 LLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVA-------------YLPQ 92
Cdd:PRK10619  20 VLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTINLVRDKDGQLKVAdknqlrllrtrltMVFQ 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  93 QLPPAEGMTVRELVAigRYPWHgALGRFGAADREKVEEAISLVGLKPLAH-RLVDSLSGGERQRAWIAMLVAQDSRCLLL 171
Cdd:PRK10619 100 HFNLWSHMTVLENVM--EAPIQ-VLGLSKQEARERAVKYLAKVGIDERAQgKYPVHLSGGQQQRVSIARALAMEPEVLLF 176

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 536036476 172 DEPTSALDIAHQVDVLSLVHRLSQErGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIM 236
Cdd:PRK10619 177 DEPTSALDPELVGEVLRIMQQLAEE-GKTMVVVTHEMGFARHVSSHVIFLHQGKIEEEGAPEQLF 240
PRK14258 PRK14258
phosphate ABC transporter ATP-binding protein; Provisional
 14-235 3.07e-20

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184593 [Multi-domain]  Cd Length: 261  Bit Score: 87.01  E-value: 3.07e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPpSEGEILLDAQpLESWSSKAFARKVAY--LP 91
Cdd:PRK14258  10 VNNLSFYYDTQKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMNE-LESEVRVEGR-VEFFNQNIYERRVNLnrLR 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  92 QQL------PPAEGMTVRELVAIGR--YPWHGALGRFGAadrekVEEAISLVGL----KPLAHRLVDSLSGGERQRAWIA 159
Cdd:PRK14258  88 RQVsmvhpkPNLFPMSVYDNVAYGVkiVGWRPKLEIDDI-----VESALKDADLwdeiKHKIHKSALDLSGGQQQRLCIA 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 160 MLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRG-----GEMIAQGTPAE 234
Cdd:PRK14258 163 RALAVKPKVLLMDEPCFGLDPIASMKVESLIQSLRLRSELTMVIVSHNLHQVSRLSDFTAFFKGnenriGQLVEFGLTKK 242


                 .
gi 536036476 235 I 235
Cdd:PRK14258 243 I 243
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 14-257 3.71e-20

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 89.11  E-value: 3.71e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPS--EGEILLDAQPLESWSSKAFARK-VAYL 90
Cdd:TIGR02633   4 MKGIVKTFGGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGVYPHGtwDGEIYWSGSPLKASNIRDTERAgIVII 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   91 PQQLPPAEGMTVRELVAIGRYPWH-GALGRFGAADReKVEEAISLVGLKPL-AHRLVDSLSGGERQRAWIAMLVAQDSRC 168
Cdd:TIGR02633  84 HQELTLVPELSVAENIFLGNEITLpGGRMAYNAMYL-RAKNLLRELQLDADnVTRPVGDYGGGQQQLVEIAKALNKQARL 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  169 LLLDEPTSALDIAHQVDVLSLVHRLsQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQgTPAEIMRGE-TLEMIYGI 247
Cdd:TIGR02633 163 LILDEPSSSLTEKETEILLDIIRDL-KAHGVACVYISHKLNEVKAVCDTICVIRDGQHVAT-KDMSTMSEDdIITMMVGR 240

                         250
                  ....*....|....
gi 536036476  248 PMGIL----PHPAG 257
Cdd:TIGR02633 241 EITSLyphePHEIG 254
dppF PRK11308
dipeptide transporter ATP-binding subunit; Provisional
 31-235 7.53e-20

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 236898 [Multi-domain]  Cd Length: 327  Bit Score: 86.94  E-value: 7.53e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  31 SLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSS---KAFARKVAYLPQQ----LPPAE--GMT 101
Cdd:PRK11308  35 SFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYYQGQDLLKADPeaqKLLRQKIQIVFQNpygsLNPRKkvGQI 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 102 VRELVAIgrypwHGALGRfgAADREKVEEAISLVGLKP-LAHRLVDSLSGGERQRAWIA---MLvaqDSRCLLLDEPTSA 177
Cdd:PRK11308 115 LEEPLLI-----NTSLSA--AERREKALAMMAKVGLRPeHYDRYPHMFSGGQRQRIAIAralML---DPDVVVADEPVSA 184

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 536036476 178 LDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEI 235
Cdd:PRK11308 185 LDVSVQAQVLNLMMDLQQELGLSYVFISHDLSVVEHIADEVMVMYLGRCVEKGTKEQI 242
artP PRK11124
arginine transporter ATP-binding subunit; Provisional
 14-231 1.08e-19

arginine transporter ATP-binding subunit; Provisional


Pssm-ID: 182980 [Multi-domain]  Cd Length: 242  Bit Score: 85.07  E-value: 1.08e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEIL-------LDAQPLESwSSKAFARK 86
Cdd:PRK11124   5 LNGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNiagnhfdFSKTPSDK-AIRELRRN 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  87 VAYLPQQ--LPPAegMTVRE-LV-AIGRypwhgALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLV 162
Cdd:PRK11124  84 VGMVFQQynLWPH--LTVQQnLIeAPCR-----VLGLSKDQALARAEKLLERLRLKPYADRFPLHLSGGQQQRVAIARAL 156

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 536036476 163 AQDSRCLLLDEPTSALD--IAHQvdVLSLVHRLSQErGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGT 231
Cdd:PRK11124 157 MMEPQVLLFDEPTAALDpeITAQ--IVSIIRELAET-GITQVIVTHEVEVARKTASRVVYMENGHIVEQGD 224
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 22-214 1.36e-19

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 87.87  E-value: 1.36e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  22 PGRTLLHPLSLTF-PAGKVtGLIGHNGSGKSTLLK-MLGRHQpPSEGEilldAQPLESWsskafarKVAYLPQQLPPAEG 99
Cdd:PRK11819  18 PKKQILKDISLSFfPGAKI-GVLGLNGAGKSTLLRiMAGVDK-EFEGE----ARPAPGI-------KVGYLPQEPQLDPE 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 100 MTVRELVAIGRYPWHGALGRFG----------------AADREKVEEAISLVGLKPLAHRL---------------VDSL 148
Cdd:PRK11819  85 KTVRENVEEGVAEVKAALDRFNeiyaayaepdadfdalAAEQGELQEIIDAADAWDLDSQLeiamdalrcppwdakVTKL 164

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 536036476 149 SGGERQRAWIAMLVAQDSRCLLLDEPTSALDiAHQVDVLSlvHRLSQERGlTVIAVLHDinmaaRY 214
Cdd:PRK11819 165 SGGERRRVALCRLLLEKPDMLLLDEPTNHLD-AESVAWLE--QFLHDYPG-TVVAVTHD-----RY 221
chvA TIGR01192
glucan exporter ATP-binding protein; This model describes glucan exporter ATP binding protein ...
 11-235 1.69e-19

glucan exporter ATP-binding protein; This model describes glucan exporter ATP binding protein in bacteria. It belongs to the larger ABC transporter superfamily with the characteristic ATP binding motif. The In general, this protein is in some ways implicated in osmoregulation and suggested to participate in the export of glucan from the cytoplasm to periplasm. The cyclic beta-1,2-glucan in the bactrerial periplasmic space is suggested to confer the property of high osmolority. It has also been demonstrated that mutants in this loci have lost functions of virulence and motility. It is unclear as to how virulence and osmoadaptaion are related. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 130260 [Multi-domain]  Cd Length: 585  Bit Score: 87.64  E-value: 1.69e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   11 TFALRNISFRVPGRTL-LHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAY 89
Cdd:TIGR01192 334 AVEFRHITFEFANSSQgVFDVSFEAKAGQTVAIVGPTGAGKTTLINLLQRVYDPTVGQILIDGIDINTVTRESLRKSIAT 413

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   90 LPQQlppaEGM---TVRELVAIGRYpwhgalgrfGAADREKVEEAISLVglkplAHRLVDS---------------LSGG 151
Cdd:TIGR01192 414 VFQD----AGLfnrSIRENIRLGRE---------GATDEEVYEAAKAAA-----AHDFILKrsngydtlvgergnrLSGG 475

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  152 ERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAvlHDINmAARYCDYLVALRGGEMIAQGT 231
Cdd:TIGR01192 476 ERQRLAIARAILKNAPILVLDEATSALDVETEARVKNAIDALRKNRTTFIIA--HRLS-TVRNADLVLFLDQGRLIEKGS 552


                  ....
gi 536036476  232 PAEI 235
Cdd:TIGR01192 553 FQEL 556
PRK14271 PRK14271
phosphate ABC transporter ATP-binding protein; Provisional
 16-247 1.78e-19

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172759 [Multi-domain]  Cd Length: 276  Bit Score: 85.15  E-value: 1.78e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  16 NISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPS-----EGEILLDAQPLESWSSK-AFARKVAY 89
Cdd:PRK14271  26 NLTLGFAGKTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMNDKVsgyrySGDVLLGGRSIFNYRDVlEFRRRVGM 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  90 LPQQlPPAEGMTVRELVAIGRYPwHGALGRfgAADREKVEEAISLVGL-KPLAHRLVDS---LSGGERQRAWIAMLVAQD 165
Cdd:PRK14271 106 LFQR-PNPFPMSIMDNVLAGVRA-HKLVPR--KEFRGVAQARLTEVGLwDAVKDRLSDSpfrLSGGQQQLLCLARTLAVN 181

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 166 SRCLLLDEPTSALDIAHQVDVLSLVHRLSQErgLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIM----RGETL 241
Cdd:PRK14271 182 PEVLLLDEPTSALDPTTTEKIEEFIRSLADR--LTVIIVTHNLAQAARISDRAALFFDGRLVEEGPTEQLFsspkHAETA 259


                 ....*.
gi 536036476 242 EMIYGI 247
Cdd:PRK14271 260 RYVAGL 265
3a01204 TIGR00955
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
 22-234 1.99e-19

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 87.41  E-value: 1.99e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   22 PGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPS---EGEILLDAQPLESWSskaFARKVAYLPQQ---LP 95
Cdd:TIGR00955  36 PRKHLLKNVSGVAKPGELLAVMGSSGAGKTTLMNALAFRSPKGvkgSGSVLLNGMPIDAKE---MRAISAYVQQDdlfIP 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   96 paeGMTVRE-LVaigrYPWHGALGRFGAAD--REKVEEAISLVGLKPLAHRL------VDSLSGGERQRAWIAMLVAQDS 166
Cdd:TIGR00955 113 ---TLTVREhLM----FQAHLRMPRRVTKKekRERVDEVLQALGLRKCANTRigvpgrVKGLSGGERKRLAFASELLTDP 185

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 536036476  167 RCLLLDEPTSALD--IAHQvdVLSLVHRLSQeRGLTVIAVLHDINmAARYC--DYLVALRGGEMIAQGTPAE 234
Cdd:TIGR00955 186 PLLFCDEPTSGLDsfMAYS--VVQVLKGLAQ-KGKTIICTIHQPS-SELFElfDKIILMAEGRVAYLGSPDQ 253
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 17-231 2.28e-19

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 87.07  E-value: 2.28e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  17 ISFRVPG--RTLLHPLSLTFPAGKVTGLIGHNGSGKS-TLLKMLGR-HQPPSE---GEILLDAQPLESWSSKAF----AR 85
Cdd:PRK15134  13 VAFRQQQtvRTVVNDVSLQIEAGETLALVGESGSGKSvTALSILRLlPSPPVVypsGDIRFHGESLLHASEQTLrgvrGN 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  86 KVAYLPQQ----LPPAEGM--TVRELVAIGRypwhgalGRFGAADREKVEEAISLVGLKPLAHRLVD---SLSGGERQRA 156
Cdd:PRK15134  93 KIAMIFQEpmvsLNPLHTLekQLYEVLSLHR-------GMRREAARGEILNCLDRVGIRQAAKRLTDyphQLSGGERQRV 165

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 536036476 157 WIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGT 231
Cdd:PRK15134 166 MIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQQELNMGLLFITHNLSIVRKLADRVAVMQNGRCVEQNR 240
livF PRK11614
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
27-245 2.44e-19

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;


Pssm-ID: 183231 [Multi-domain]  Cd Length: 237  Bit Score: 84.16  E-value: 2.44e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  27 LHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARK-VAYLPQQLPPAEGMTVREL 105
Cdd:PRK11614  21 LHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDITDWQTAKIMREaVAIVPEGRRVFSRMTVEEN 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 106 VAIGrypwhgalGRFgaADREKVEEAISLV-GLKP-LAHRLVD---SLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDI 180
Cdd:PRK11614 101 LAMG--------GFF--AERDQFQERIKWVyELFPrLHERRIQragTMSGGEQQMLAIGRALMSQPRLLLLDEPSLGLAP 170

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 536036476 181 AHQVDVLSLVHRLSQErGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMRGETLEMIY 245
Cdd:PRK11614 171 IIIQQIFDTIEQLREQ-GMTIFLVEQNANQALKLADRGYVLENGHVVLEDTGDALLANEAVRSAY 234
cbiO PRK13646
energy-coupling factor transporter ATPase;
27-237 2.98e-19

energy-coupling factor transporter ATPase;


Pssm-ID: 184205 [Multi-domain]  Cd Length: 286  Bit Score: 84.83  E-value: 2.98e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  27 LHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAF---ARKVAYLPQQLPPA---EGM 100
Cdd:PRK13646  23 IHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITITHKTKDKYirpVRKRIGMVFQFPESqlfEDT 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 101 TVRELVaigrypwhgalgrFGAAD-REKVEEAislvglKPLAHRLVDSL--------------SGGERQRAWIAMLVAQD 165
Cdd:PRK13646 103 VEREII-------------FGPKNfKMNLDEV------KNYAHRLLMDLgfsrdvmsqspfqmSGGQMRKIAIVSILAMN 163

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 536036476 166 SRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMR 237
Cdd:PRK13646 164 PDIIVLDEPTAGLDPQSKRQVMRLLKSLQTDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKELFK 235
ABCD_peroxisomal_ALDP cd03223
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ...
 12-206 4.85e-19

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).


Pssm-ID: 213190 [Multi-domain]  Cd Length: 166  Bit Score: 81.43  E-value: 4.85e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  12 FALRNISFRVP-GRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEIlldaqpleswsSKAFARKVAYL 90
Cdd:cd03223    1 IELENLSLATPdGRVLLKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWGSGRI-----------GMPEGEDLLFL 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  91 PQQ--LPPAegmTVRELVAigrYPWHgalgrfgaadrekveeaislvglkplahrlvDSLSGGERQRAWIAMLVAQDSRC 168
Cdd:cd03223   70 PQRpyLPLG---TLREQLI---YPWD-------------------------------DVLSGGEQQRLAFARLLLHKPKF 112

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 536036476 169 LLLDEPTSALDiahqVDVLSLVHRLSQERGLTVIAVLH 206
Cdd:cd03223  113 VFLDEATSALD----EESEDRLYQLLKELGITVISVGH 146
COG4586 COG4586
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 13-235 6.61e-19

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443643 [Multi-domain]  Cd Length: 323  Bit Score: 84.37  E-value: 6.61e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  13 ALRNISFRVPgrtllhplsltfpAGKVTGLIGHNGSGKSTLLKML-G-RHqpPSEGEIL-LDAQPLEswSSKAFARKVAY 89
Cdd:COG4586   37 AVDDISFTIE-------------PGEIVGFIGPNGAGKSTTIKMLtGiLV--PTSGEVRvLGYVPFK--RRKEFARRIGV 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  90 L---PQQL----PPAEGmtvrelvaigrYPWHGALGRFGAAD-REKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAML 161
Cdd:COG4586  100 VfgqRSQLwwdlPAIDS-----------FRLLKAIYRIPDAEyKKRLDELVELLDLGELLDTPVRQLSLGQRMRCELAAA 168

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 536036476 162 VAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEI 235
Cdd:COG4586  169 LLHRPKILFLDEPTIGLDVVSKEAIREFLKEYNRERGTTILLTSHDMDDIEALCDRVIVIDHGRIIYDGSLEEL 242
phnK PRK11701
phosphonate C-P lyase system protein PhnK; Provisional
 15-230 6.62e-19

phosphonate C-P lyase system protein PhnK; Provisional


Pssm-ID: 183280 [Multi-domain]  Cd Length: 258  Bit Score: 83.44  E-value: 6.62e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  15 RNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILL---DAQPLESWS-SKAFARKVA-- 88
Cdd:PRK11701  10 RGLTKLYGPRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYrmrDGQLRDLYAlSEAERRRLLrt 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  89 ---YLPQQlpPAEG--MTV-------RELVAIG-RYpwHGALgRFGAAD-REKVEEAISlvglkplahRLVD---SLSGG 151
Cdd:PRK11701  90 ewgFVHQH--PRDGlrMQVsaggnigERLMAVGaRH--YGDI-RATAGDwLERVEIDAA---------RIDDlptTFSGG 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 536036476 152 ERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQG 230
Cdd:PRK11701 156 MQQRLQIARNLVTHPRLVFMDEPTGGLDVSVQARLLDLLRGLVRELGLAVVIVTHDLAVARLLAHRLLVMKQGRVVESG 234
ABCC_MRP_domain1 cd03250
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...
 5-225 9.99e-19

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213217 [Multi-domain]  Cd Length: 204  Bit Score: 81.75  E-value: 9.99e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   5 TNHSDTTFALRNISFrvpgrtllhplslTFPAGKVTGLIGHNGSGKSTLLK-MLGrHQPPSEGEIlldaqpleswsskAF 83
Cdd:cd03250   12 SGEQETSFTLKDINL-------------EVPKGELVAIVGPVGSGKSSLLSaLLG-ELEKLSGSV-------------SV 64

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  84 ARKVAYLPQQlPPAEGMTVRELVAIGrYPWhgalgrfgaaDREKVEEAISLVGLKPLAHRLVD-----------SLSGGE 152
Cdd:cd03250   65 PGSIAYVSQE-PWIQNGTIRENILFG-KPF----------DEERYEKVIKACALEPDLEILPDgdlteigekgiNLSGGQ 132

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 536036476 153 RQRAWIAMLVAQDSRCLLLDEPTSALD------IAHQVdvlsLVHRLSQERglTVIAVLHDINmAARYCDYLVALRGGE 225
Cdd:cd03250  133 KQRISLARAVYSDADIYLLDDPLSAVDahvgrhIFENC----ILGLLLNNK--TRILVTHQLQ-LLPHADQIVVLDNGR 204
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 30-237 1.05e-18

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 85.24  E-value: 1.05e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   30 LSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEI----------LLDAQPLESWSSKafaRKVAYLPQQLPPAEG 99
Cdd:TIGR03269 303 VSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVnvrvgdewvdMTKPGPDGRGRAK---RYIGILHQEYDLYPH 379

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  100 MTVRELV--AIG-RYPWHgaLGRFGAA--------DREKVEEAISlvglkplahRLVDSLSGGERQRAWIAMLVAQDSRC 168
Cdd:TIGR03269 380 RTVLDNLteAIGlELPDE--LARMKAVitlkmvgfDEEKAEEILD---------KYPDELSEGERHRVALAQVLIKEPRI 448

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 536036476  169 LLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMR 237
Cdd:TIGR03269 449 VILDEPTGTMDPITKVDVTHSILKAREEMEQTFIIVSHDMDFVLDVCDRAALMRDGKIVKIGDPEEIVE 517
PRK10584 PRK10584
putative ABC transporter ATP-binding protein YbbA; Provisional
 25-226 1.08e-18

putative ABC transporter ATP-binding protein YbbA; Provisional


Pssm-ID: 182569 [Multi-domain]  Cd Length: 228  Bit Score: 82.13  E-value: 1.08e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  25 TLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPL----ESWSSKAFARKVAYLPQQLPPAEGM 100
Cdd:PRK10584  24 SILTGVELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLhqmdEEARAKLRAKHVGFVFQSFMLIPTL 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 101 TVRELVAIgrypwhGALGRfGAADREKVEEAISL---VGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSA 177
Cdd:PRK10584 104 NALENVEL------PALLR-GESSRQSRNGAKALleqLGLGKRLDHLPAQLSGGEQQRVALARAFNGRPDVLFADEPTGN 176

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 536036476 178 LDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARyCDYLVALRGGEM 226
Cdd:PRK10584 177 LDRQTGDKIADLLFSLNREHGTTLILVTHDLQLAAR-CDRRLRLVNGQL 224
ABCG_PDR_domain2 cd03232
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ...
 12-227 1.26e-18

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213199 [Multi-domain]  Cd Length: 192  Bit Score: 81.14  E-value: 1.26e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  12 FALRNISFRVPG----RTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLG--RHQPPSEGEILLDAQPLEswssKAFAR 85
Cdd:cd03232    4 LTWKNLNYTVPVkggkRQLLNNISGYVKPGTLTALMGESGAGKTTLLDVLAgrKTAGVITGEILINGRPLD----KNFQR 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  86 KVAYLPQQLPPAEGMTVRElvaigrypwhgALgRFGAADREkveeaislvglkplahrlvdsLSGGERQRAWIAMLVAQD 165
Cdd:cd03232   80 STGYVEQQDVHSPNLTVRE-----------AL-RFSALLRG---------------------LSVEQRKRLTIGVELAAK 126

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 536036476 166 SRCLLLDEPTSALDIAHQVDVLSLVHRLSqERGLTVIAVLHDINMAA-RYCDYLVAL-RGGEMI 227
Cdd:cd03232  127 PSILFLDEPTSGLDSQAAYNIVRFLKKLA-DSGQAILCTIHQPSASIfEKFDRLLLLkRGGKTV 189
PRK11174 PRK11174
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 23-237 2.20e-18

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236870 [Multi-domain]  Cd Length: 588  Bit Score: 84.13  E-value: 2.20e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  23 GRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKM-LGRHqpPSEGEILLDAQPLESWSSKAFARKVAYLPQ--QLPPAeg 99
Cdd:PRK11174 362 GKTLAGPLNFTLPAGQRIALVGPSGAGKTSLLNAlLGFL--PYQGSLKINGIELRELDPESWRKHLSWVGQnpQLPHG-- 437

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 100 mTVRELVAIGRYpwhgalgrfgAADREKVEEAISLVGLKPLAHRLVD-----------SLSGGERQRAWIAMLVAQDSRC 168
Cdd:PRK11174 438 -TLRDNVLLGNP----------DASDEQLQQALENAWVSEFLPLLPQgldtpigdqaaGLSVGQAQRLALARALLQPCQL 506

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 536036476 169 LLLDEPTSALDIAHQVDVLSLVHRLSQerGLTVIAVLHDINMAARyCDYLVALRGGEMIAQGTPAEIMR 237
Cdd:PRK11174 507 LLLDEPTASLDAHSEQLVMQALNAASR--RQTTLMVTHQLEDLAQ-WDQIWVMQDGQIVQQGDYAELSQ 572
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
31-242 2.28e-18

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 84.41  E-value: 2.28e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  31 SLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESwSSKAFARKVAYLPQQLPPAEGMTVRE-LVAig 109
Cdd:NF033858 286 SFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPVDA-GDIATRRRVGYMSQAFSLYGELTVRQnLEL-- 362

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 110 rypwHGALGRFGAADREK-VEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLS 188
Cdd:NF033858 363 ----HARLFHLPAAEIAArVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSGVDPVARDMFWR 438

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 536036476 189 LVHRLSQERGLTVIAVLHDINMAARyCDYLVALRGGEMIAQGTPAEIMR---GETLE 242
Cdd:NF033858 439 LLIELSREDGVTIFISTHFMNEAER-CDRISLMHAGRVLASDTPAALVAargAATLE 494
PRK10908 PRK10908
cell division ATP-binding protein FtsE;
23-226 3.88e-18

cell division ATP-binding protein FtsE;


Pssm-ID: 182829 [Multi-domain]  Cd Length: 222  Bit Score: 80.69  E-value: 3.88e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  23 GRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLeswsSKAFARKVAYLPQQLppaeGM-- 100
Cdd:PRK10908  14 GRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDI----TRLKNREVPFLRRQI----GMif 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 101 ---------TVRELVAIgryPWHGAlGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLL 171
Cdd:PRK10908  86 qdhhllmdrTVYDNVAI---PLIIA-GASGDDIRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPAVLLA 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 536036476 172 DEPTSALDIAHQVDVLSLVHRLSQErGLTVIAVLHDINMAARYCDYLVALRGGEM 226
Cdd:PRK10908 162 DEPTGNLDDALSEGILRLFEEFNRV-GVTVLMATHDIGLISRRSYRMLTLSDGHL 215
PRK10535 PRK10535
macrolide ABC transporter ATP-binding protein/permease MacB;
27-228 4.47e-18

macrolide ABC transporter ATP-binding protein/permease MacB;


Pssm-ID: 182528 [Multi-domain]  Cd Length: 648  Bit Score: 83.23  E-value: 4.47e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  27 LHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFAR----------KVAYLPQQLPP 96
Cdd:PRK10535  24 LKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVATLDADALAQlrrehfgfifQRYHLLSHLTA 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  97 AEGMTVRELVAigrypwhgalgrfGAADREKVEEAISLVGLKPLAHRL---VDSLSGGERQRAWIAMLVAQDSRCLLLDE 173
Cdd:PRK10535 104 AQNVEVPAVYA-------------GLERKQRLLRAQELLQRLGLEDRVeyqPSQLSGGQQQRVSIARALMNGGQVILADE 170

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 536036476 174 PTSALDIAHQVDVLSLVHRLsQERGLTVIAVLHDINMAARyCDYLVALRGGEMIA 228
Cdd:PRK10535 171 PTGALDSHSGEEVMAILHQL-RDRGHTVIIVTHDPQVAAQ-AERVIEIRDGEIVR 223
modC PRK11144
molybdenum ABC transporter ATP-binding protein ModC;
32-235 4.93e-18

molybdenum ABC transporter ATP-binding protein ModC;


Pssm-ID: 182993 [Multi-domain]  Cd Length: 352  Bit Score: 82.23  E-value: 4.93e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  32 LTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAF----ARKVAYLPQ--QLPPAegMTVRel 105
Cdd:PRK11144  19 LTLPAQGITAIFGRSGAGKTSLINAISGLTRPQKGRIVLNGRVLFDAEKGIClppeKRRIGYVFQdaRLFPH--YKVR-- 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 106 vaigrypwhGALgRFGAA--DREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWI--AMLVAQDsrCLLLDEPTSALDIA 181
Cdd:PRK11144  95 ---------GNL-RYGMAksMVAQFDKIVALLGIEPLLDRYPGSLSGGEKQRVAIgrALLTAPE--LLLMDEPLASLDLP 162

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 536036476 182 HQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEI 235
Cdd:PRK11144 163 RKRELLPYLERLAREINIPILYVSHSLDEILRLADRVVVLEQGKVKAFGPLEEV 216
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
14-242 5.13e-18

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 83.25  E-value: 5.13e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLG---RHQppsEGEI-LLDAQPLESWSSKAFARKVAY 89
Cdd:NF033858   4 LEGVSHRYGKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAgarKIQ---QGRVeVLGGDMADARHRRAVCPRIAY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  90 LPQQLppaeG------MTVRELVAigrypWHGALgrFG--AADRE-KVEEAISLVGLKPLAHRLVDSLSGGERQR----- 155
Cdd:NF033858  81 MPQGL----GknlyptLSVFENLD-----FFGRL--FGqdAAERRrRIDELLRATGLAPFADRPAGKLSGGMKQKlglcc 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 156 AWIamlvaQDSRCLLLDEPTSAldiahqVDVLS------LVHRLSQER-GLTVIAVLHDINMAARYcDYLVALRGGEMIA 228
Cdd:NF033858 150 ALI-----HDPDLLILDEPTTG------VDPLSrrqfweLIDRIRAERpGMSVLVATAYMEEAERF-DWLVAMDAGRVLA 217

                        250
                 ....*....|....*..
gi 536036476 229 QGTPAEIMR---GETLE 242
Cdd:NF033858 218 TGTPAELLArtgADTLE 234
PRK14239 PRK14239
phosphate transporter ATP-binding protein; Provisional
 27-246 6.85e-18

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184585 [Multi-domain]  Cd Length: 252  Bit Score: 80.59  E-value: 6.85e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  27 LHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRH-----QPPSEGEILLDAQPLESWSSKAFA-RKVAYLPQQLPPAEGM 100
Cdd:PRK14239  21 LNSVSLDFYPNEITALIGPSGSGKSTLLRSINRMndlnpEVTITGSIVYNGHNIYSPRTDTVDlRKEIGMVFQQPNPFPM 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 101 TVRELVAIGrypwhgaLGRFGAADREKVEEAI--SLVGLK---PLAHRLVDS---LSGGERQRAWIAMLVAQDSRCLLLD 172
Cdd:PRK14239 101 SIYENVVYG-------LRLKGIKDKQVLDEAVekSLKGASiwdEVKDRLHDSalgLSGGQQQRVCIARVLATSPKIILLD 173

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 536036476 173 EPTSALDIAHQVDVLSLVHRLSQErgLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIM----RGETLEMIYG 246
Cdd:PRK14239 174 EPTSALDPISAGKIEETLLGLKDD--YTMLLVTRSMQQASRISDRTGFFLDGDLIEYNDTKQMFmnpkHKETEDYISG 249
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 14-250 8.80e-18

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 82.47  E-value: 8.80e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSK-AFARKVAYLPQ 92
Cdd:PRK10982   1 MSNISKSFPGVKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEIDFKSSKeALENGISMVHQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  93 QLPPAEGMTVRELVAIGRYPWHGALgrfgaADREKV---EEAI-SLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRC 168
Cdd:PRK10982  81 ELNLVLQRSVMDNMWLGRYPTKGMF-----VDQDKMyrdTKAIfDELDIDIDPRAKVATLSVSQMQMIEIAKAFSYNAKI 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 169 LLLDEPTSALDiAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAqgtpAEIMRGETLEMIYGIP 248
Cdd:PRK10982 156 VIMDEPTSSLT-EKEVNHLFTIIRKLKERGCGIVYISHKMEEIFQLCDEITILRDGQWIA----TQPLAGLTMDKIIAMM 230


                 ..
gi 536036476 249 MG 250
Cdd:PRK10982 231 VG 232
PRK15112 PRK15112
peptide ABC transporter ATP-binding protein SapF;
11-236 1.04e-17

peptide ABC transporter ATP-binding protein SapF;


Pssm-ID: 185067 [Multi-domain]  Cd Length: 267  Bit Score: 80.22  E-value: 1.04e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  11 TFALRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYL 90
Cdd:PRK15112  13 TFRYRTGWFRRQTVEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLHFGDYSYRSQRIRMI 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  91 PQQlpPAEGMTVRELVA-IGRYPWHGALGRFGAADREKVEEAISLVGLKP-LAHRLVDSLSGGERQRAWIAMLVAQDSRC 168
Cdd:PRK15112  93 FQD--PSTSLNPRQRISqILDFPLRLNTDLEPEQREKQIIETLRQVGLLPdHASYYPHMLAPGQKQRLGLARALILRPKV 170

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 536036476 169 LLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIM 236
Cdd:PRK15112 171 IIADEALASLDMSMRSQLINLMLELQEKQGISYIYVTQHLGMMKHISDQVLVMHQGEVVERGSTADVL 238
sufC TIGR01978
FeS assembly ATPase SufC; SufC is part of the SUF system, shown in E. coli to consist of six ...
 14-202 1.08e-17

FeS assembly ATPase SufC; SufC is part of the SUF system, shown in E. coli to consist of six proteins and believed to act in Fe-S cluster formation during oxidative stress. SufC forms a complex with SufB and SufD. SufC belongs to the ATP-binding cassette transporter family (pfam00005) but is no longer thought to be part of a transporter. The complex is reported as cytosolic () or associated with the membrane (). The SUF system also includes a cysteine desulfurase (SufS, enhanced by SufE) and a probable iron-sulfur cluster assembly scaffold protein, SufA. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]


Pssm-ID: 273907 [Multi-domain]  Cd Length: 243  Bit Score: 79.61  E-value: 1.08e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHqPPSE---GEILLDAQPLESWSSKAFARKVAYL 90
Cdd:TIGR01978   3 IKDLHVSVEDKEILKGVNLTVKKGEIHAIMGPNGSGKSTLSKTIAGH-PSYEvtsGTILFKGQDLLELEPDERARAGLFL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   91 PQQLPPA-EGMTVRELV-----AIGRYPWHGALGRFgaADREKVEEAISLVGLKP-LAHRLV-DSLSGGERQRAWIAMLV 162
Cdd:TIGR01978  82 AFQYPEEiPGVSNLEFLrsalnARRSARGEEPLDLL--DFEKLLKEKLALLDMDEeFLNRSVnEGFSGGEKKRNEILQMA 159

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 536036476  163 AQDSRCLLLDEPTSALDIAHQVDVLSLVHRL-SQERGLTVI 202
Cdd:TIGR01978 160 LLEPKLAILDEIDSGLDIDALKIVAEGINRLrEPDRSFLII 200
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 23-180 2.64e-17

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 81.13  E-value: 2.64e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   23 GRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKML-GRHQPPSeGEILLDAqpleswsskafARKVAYLPQQ---LPPAE 98
Cdd:TIGR03719 334 DKLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMItGQEQPDS-GTIEIGE-----------TVKLAYVDQSrdaLDPNK 401

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   99 gmTVRELVA-------IGRY--PWHGALGRFG--AADREKveeaislvglkplahrLVDSLSGGERQRAWIAMLVAQDSR 167
Cdd:TIGR03719 402 --TVWEEISggldiikLGKReiPSRAYVGRFNfkGSDQQK----------------KVGQLSGGERNRVHLAKTLKSGGN 463

                         170
                  ....*....|...
gi 536036476  168 CLLLDEPTSALDI 180
Cdd:TIGR03719 464 VLLLDEPTNDLDV 476
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 13-246 3.37e-17

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 80.82  E-value: 3.37e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  13 ALRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAF-ARKVAYLP 91
Cdd:PRK10762   6 QLKGIDKAFPGVKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGKEVTFNGPKSSqEAGIGIIH 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  92 QQLPPAEGMTVRELVAIGRYPwhgaLGRFGAADREKV-EEAISL---VGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSR 167
Cdd:PRK10762  86 QELNLIPQLTIAENIFLGREF----VNRFGRIDWKKMyAEADKLlarLNLRFSSDKLVGELSIGEQQMVEIAKVLSFESK 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 168 CLLLDEPTSALDIAHQVDVLSLVHRL-SQERGLTVIAvlHDINMAARYCDYLVALRGGEMIAQGTPAEIMRGETLEMIYG 246
Cdd:PRK10762 162 VIIMDEPTDALTDTETESLFRVIRELkSQGRGIVYIS--HRLKEIFEICDDVTVFRDGQFIAEREVADLTEDSLIEMMVG 239
ABC_FeS_Assembly cd03217
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...
 14-237 3.45e-17

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.


Pssm-ID: 213184 [Multi-domain]  Cd Length: 200  Bit Score: 77.57  E-value: 3.45e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKML-GRHQP-PSEGEILLDAQPLESWSSKAFARKVAYLP 91
Cdd:cd03217    3 IKDLHVSVGGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTImGHPKYeVTEGEILFKGEDITDLPPEERARLGIFLA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  92 QQLPPA-EGMTVRELVaigRYpwhgalgrfgaadrekveeaislvglkplahrLVDSLSGGERQRAWIAMLVAQDSRCLL 170
Cdd:cd03217   83 FQYPPEiPGVKNADFL---RY--------------------------------VNEGFSGGEKKRNEILQLLLLEPDLAI 127

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 536036476 171 LDEPTSALDIahqvDVLSLVHRLSQ---ERGLTVIAVLHDINMAarycDYLVA-----LRGGEMIAQGtPAEIMR 237
Cdd:cd03217  128 LDEPDSGLDI----DALRLVAEVINklrEEGKSVLIITHYQRLL----DYIKPdrvhvLYDGRIVKSG-DKELAL 193
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 14-235 3.72e-17

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 80.62  E-value: 3.72e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKML-GRHQ-PPSEGEIL---------------------- 69
Cdd:TIGR03269   3 VKNLTKKFDGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLrGMDQyEPTSGRIIyhvalcekcgyverpskvgepc 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   70 ------LDAQPLESWS-----SKAFARKVAYLPQQ-LPPAEGMTVRELVAigrypwhGALGRFGAADREKVEEAISLVGL 137
Cdd:TIGR03269  83 pvcggtLEPEEVDFWNlsdklRRRIRKRIAIMLQRtFALYGDDTVLDNVL-------EALEEIGYEGKEAVGRAVDLIEM 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  138 KPLAHRLVD---SLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARY 214
Cdd:TIGR03269 156 VQLSHRITHiarDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASGISMVLTSHWPEVIEDL 235

                         250       260
                  ....*....|....*....|.
gi 536036476  215 CDYLVALRGGEMIAQGTPAEI 235
Cdd:TIGR03269 236 SDKAIWLENGEIKEEGTPDEV 256
ABCC_MRP_domain2 cd03244
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...
 16-232 3.93e-17

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213211 [Multi-domain]  Cd Length: 221  Bit Score: 77.53  E-value: 3.93e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  16 NISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQQlP 95
Cdd:cd03244    9 SLRYRPNLPPVLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGVDISKIGLHDLRSRISIIPQD-P 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  96 PAEGMTVRElvaigrypwhgALGRFGAADREKVEEAISLVGLK------PLAHRLV-----DSLSGGERQ-----RawiA 159
Cdd:cd03244   88 VLFSGTIRS-----------NLDPFGEYSDEELWQALERVGLKefveslPGGLDTVveeggENLSVGQRQllclaR---A 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 536036476 160 MLvaQDSRCLLLDEPTSALDiaHQVDvlSLVHRLSQE--RGLTVIAVLHDINMAARYcDYLVALRGGEMIAQGTP 232
Cdd:cd03244  154 LL--RKSKILVLDEATASVD--PETD--ALIQKTIREafKDCTVLTIAHRLDTIIDS-DRILVLDKGRVVEFDSP 221
PRK11264 PRK11264
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
 14-230 4.60e-17

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional


Pssm-ID: 183063 [Multi-domain]  Cd Length: 250  Bit Score: 78.25  E-value: 4.60e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEG-----EILLDA-QPLESWSS--KAFAR 85
Cdd:PRK11264   6 VKNLVKKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGtirvgDITIDTaRSLSQQKGliRQLRQ 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  86 KVAYLPQQLPPAEGMTVRELVAIGRYpwhgalgrfgAADREKVEEAISL-------VGLKPLAHRLVDSLSGGERQRAWI 158
Cdd:PRK11264  86 HVGFVFQNFNLFPHRTVLENIIEGPV----------IVKGEPKEEATARarellakVGLAGKETSYPRRLSGGQQQRVAI 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 536036476 159 AMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIaVLHDINMAARYCDYLVALRGGEMIAQG 230
Cdd:PRK11264 156 ARALAMRPEVILFDEPTSALDPELVGEVLNTIRQLAQEKRTMVI-VTHEMSFARDVADRAIFMDQGRIVEQG 226
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 19-232 6.58e-17

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 80.44  E-value: 6.58e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476    19 FRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESwSSKAFARKVAYLPQQLPPAE 98
Cdd:TIGR01257  938 FEPSGRPAVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDIET-NLDAVRQSLGMCPQHNILFH 1016

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476    99 GMTVRELVAIgrypWHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSAL 178
Cdd:TIGR01257 1017 HLTVAEHILF----YAQLKGRSWEEAQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPTSGV 1092

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 536036476   179 DIAHQVDVLSLVhrLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTP 232
Cdd:TIGR01257 1093 DPYSRRSIWDLL--LKYRSGRTIIMSTHHMDEADLLGDRIAIISQGRLYCSGTP 1144
PRK14267 PRK14267
phosphate ABC transporter ATP-binding protein; Provisional
 12-235 1.57e-16

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184596 [Multi-domain]  Cd Length: 253  Bit Score: 76.80  E-value: 1.57e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  12 FALRNISFRV--PGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGR-----HQPPSEGEILL--------DAQPLE 76
Cdd:PRK14267   3 FAIETVNLRVyyGSNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRllelnEEARVEGEVRLfgrniyspDVDPIE 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  77 swsskaFARKVAYLPQQLPPAEGMTVRELVAIGrYPWHGALGRFGAADrEKVEEAISLVGL-KPLAHRLVD---SLSGGE 152
Cdd:PRK14267  83 ------VRREVGMVFQYPNPFPHLTIYDNVAIG-VKLNGLVKSKKELD-ERVEWALKKAALwDEVKDRLNDypsNLSGGQ 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 153 RQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQErgLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTP 232
Cdd:PRK14267 155 RQRLVIARALAMKPKILLMDEPTANIDPVGTAKIEELLFELKKE--YTIVLVTHSPAQAARVSDYVAFLYLGKLIEVGPT 232


                 ...
gi 536036476 233 AEI 235
Cdd:PRK14267 233 RKV 235
PRK13657 PRK13657
glucan ABC transporter ATP-binding protein/ permease;
15-203 1.69e-16

glucan ABC transporter ATP-binding protein/ permease;


Pssm-ID: 184214 [Multi-domain]  Cd Length: 588  Bit Score: 78.85  E-value: 1.69e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  15 RNISFRVPG-RTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQq 93
Cdd:PRK13657 338 DDVSFSYDNsRQGVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGTDIRTVTRASLRRNIAVVFQ- 416

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  94 lppaEGM----TVRELVAIGRYpwhgalgrfGAADREKVE-----EAISLVGLKPLAHRLV-----DSLSGGERQRAWIA 159
Cdd:PRK13657 417 ----DAGlfnrSIEDNIRVGRP---------DATDEEMRAaaeraQAHDFIERKPDGYDTVvgergRQLSGGERQRLAIA 483

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 536036476 160 MLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIA 203
Cdd:PRK13657 484 RALLKDPPILILDEATSALDVETEAKVKAALDELMKGRTTFIIA 527
PRK15079 PRK15079
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
 31-208 2.72e-16

oligopeptide ABC transporter ATP-binding protein OppF; Provisional


Pssm-ID: 185037 [Multi-domain]  Cd Length: 331  Bit Score: 77.05  E-value: 2.72e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  31 SLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAF--ARKVAYLPQQLPPAE---GMTVREL 105
Cdd:PRK15079  41 TLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAWLGKDLLGMKDDEWraVRSDIQMIFQDPLASlnpRMTIGEI 120

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 106 VAIGRYPWHGALGRfgAADREKVEEAISLVGLKP-LAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQV 184
Cdd:PRK15079 121 IAEPLRTYHPKLSR--QEVKDRVKAMMLKVGLLPnLINRYPHEFSGGQCQRIGIARALILEPKLIICDEPVSALDVSIQA 198

                        170       180
                 ....*....|....*....|....
gi 536036476 185 DVLSLVHRLSQERGLTVIAVLHDI 208
Cdd:PRK15079 199 QVVNLLQQLQREMGLSLIFIAHDL 222
ABCG_PDR_domain1 cd03233
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ...
 11-230 2.87e-16

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213200 [Multi-domain]  Cd Length: 202  Bit Score: 74.99  E-value: 2.87e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  11 TFALRNISFRV----PGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPS---EGEILLDAQPLESWSSKaF 83
Cdd:cd03233    3 TLSWRNISFTTgkgrSKIPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRTEGNvsvEGDIHYNGIPYKEFAEK-Y 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  84 ARKVAYLPQQ-LPPAEgMTVRELVaigrypwhgalgrfgaadrekvEEAISLVGlkplaHRLVDSLSGGERQRAWIAMLV 162
Cdd:cd03233   82 PGEIIYVSEEdVHFPT-LTVRETL----------------------DFALRCKG-----NEFVRGISGGERKRVSIAEAL 133

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 536036476 163 AQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYC-DYLVALRGGEMIAQG 230
Cdd:cd03233  134 VSRASVLCWDNSTRGLDSSTALEILKCIRTMADVLKTTTFVSLYQASDEIYDLfDKVLVLYEGRQIYYG 202
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
20-226 4.10e-16

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 77.26  E-value: 4.10e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  20 RVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSK-AFARKVAYLPQQlPPAE 98
Cdd:PRK11288 262 GLKGPGLREPISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGKPIDIRSPRdAIRAGIMLCPED-RKAE 340

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  99 GM----TVRELVAIGRYPWHGALGRF--GAADREKVEEAISLVGLK-PLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLL 171
Cdd:PRK11288 341 GIipvhSVADNINISARRHHLRAGCLinNRWEAENADRFIRSLNIKtPSREQLIMNLSGGNQQKAILGRWLSEDMKVILL 420

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 536036476 172 DEPTSALDIAHQVDVLSLVHRLSqERGLTVIAVLHDINMAARYCDYLVALRGGEM 226
Cdd:PRK11288 421 DEPTRGIDVGAKHEIYNVIYELA-AQGVAVLFVSSDLPEVLGVADRIVVMREGRI 474
PvdE COG4615
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ...
 10-228 7.48e-16

ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];


Pssm-ID: 443659 [Multi-domain]  Cd Length: 547  Bit Score: 76.76  E-value: 7.48e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  10 TTFALRNISFRVPGRT-----LLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFA 84
Cdd:COG4615  326 QTLELRGVTYRYPGEDgdegfTLGPIDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPESGEILLDGQPVTADNREAYR 405

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  85 RKVA------YLPQQLPPAEGMTVRELVAigRYpwhgaLGRFGAADREKVEEaislvglkplaHRLVD-SLSGGERQRaw 157
Cdd:COG4615  406 QLFSavfsdfHLFDRLLGLDGEADPARAR--EL-----LERLELDHKVSVED-----------GRFSTtDLSQGQRKR-- 465

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 158 IAMLVA--QDSRCLLLDEPTsaldiAHQ------VDVLSLVHRLsQERGLTVIAVLHDinmaARY---CDYLVALRGGEM 226
Cdd:COG4615  466 LALLVAllEDRPILVFDEWA-----ADQdpefrrVFYTELLPEL-KARGKTVIAISHD----DRYfdlADRVLKMDYGKL 535


                 ..
gi 536036476 227 IA 228
Cdd:COG4615  536 VE 537
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
 14-207 7.93e-16

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 76.47  E-value: 7.93e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEIlldaqpleSWSSKAfarKVAYLPQQ 93
Cdd:PRK15064 322 VENLTKGFDNGPLFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTV--------KWSENA---NIGYYAQD 390

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  94 LPP--AEGMTVRELVAIGRYPWH------GALGR--FGAADREKVeeaislvglkplahrlVDSLSGGERQRAWIAMLVA 163
Cdd:PRK15064 391 HAYdfENDLTLFDWMSQWRQEGDdeqavrGTLGRllFSQDDIKKS----------------VKVLSGGEKGRMLFGKLMM 454

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 536036476 164 QDSRCLLLDEPTSALDIAhqvDVLSLVHRLSQERGlTVIAVLHD 207
Cdd:PRK15064 455 QKPNVLVMDEPTNHMDME---SIESLNMALEKYEG-TLIFVSHD 494
znuC PRK09544
high-affinity zinc transporter ATPase; Reviewed
 10-232 1.54e-15

high-affinity zinc transporter ATPase; Reviewed


Pssm-ID: 181939 [Multi-domain]  Cd Length: 251  Bit Score: 73.99  E-value: 1.54e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  10 TTFALRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQpleswsskafaRKVAY 89
Cdd:PRK09544   3 SLVSLENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIKRNGK-----------LRIGY 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  90 LPQQ--LPPAEGMTVRELVAIgrypwhgalgrfgaadREKVEEAISLVGLKPL-AHRLVDS----LSGGERQRAWIAMLV 162
Cdd:PRK09544  72 VPQKlyLDTTLPLTVNRFLRL----------------RPGTKKEDILPALKRVqAGHLIDApmqkLSGGETQRVLLARAL 135

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 163 AQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALrGGEMIAQGTP 232
Cdd:PRK09544 136 LNRPQLLVLDEPTQGVDVNGQVALYDLIDQLRRELDCAVLMVSHDLHLVMAKTDEVLCL-NHHICCSGTP 204
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
 11-206 1.60e-15

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 76.30  E-value: 1.60e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476    11 TFALRNISFRVP----GRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPP---SEGEILLDAQPLESwsskAF 83
Cdd:TIGR00956  759 IFHWRNLTYEVKikkeKRVILNNVDGWVKPGTLTALMGASGAGKTTLLNVLAERVTTgviTGGDRLVNGRPLDS----SF 834

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476    84 ARKVAYLPQQLPPAEGMTVRElvaigrypwhgALgRFGAADR--------EK---VEEAISLVGLKPLAHRLV----DSL 148
Cdd:TIGR00956  835 QRSIGYVQQQDLHLPTSTVRE-----------SL-RFSAYLRqpksvsksEKmeyVEEVIKLLEMESYADAVVgvpgEGL 902

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 536036476   149 SGGERQRAWIAM-LVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSqERGLTVIAVLH 206
Cdd:TIGR00956  903 NVEQRKRLTIGVeLVAKPKLLLFLDEPTSGLDSQTAWSICKLMRKLA-DHGQAILCTIH 960
PRK13538 PRK13538
cytochrome c biogenesis heme-transporting ATPase CcmA;
15-202 2.07e-15

cytochrome c biogenesis heme-transporting ATPase CcmA;


Pssm-ID: 184125 [Multi-domain]  Cd Length: 204  Bit Score: 72.53  E-value: 2.07e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  15 RNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESwSSKAFARKVAYLPQQ- 93
Cdd:PRK13538   5 RNLACERDERILFSGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPIRR-QRDEYHQDLLYLGHQp 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  94 -----LPPAEGMTvrelvaigrypWHGALGrfGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRC 168
Cdd:PRK13538  84 gikteLTALENLR-----------FYQRLH--GPGDDEALWEALAQVGLAGFEDVPVRQLSAGQQRRVALARLWLTRAPL 150

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 536036476 169 LLLDEPTSALDiAHQVDVlsLVHRLSQ--ERGLTVI 202
Cdd:PRK13538 151 WILDEPFTAID-KQGVAR--LEALLAQhaEQGGMVI 183
ABC_Carb_Monos_II cd03215
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 12-226 2.23e-15

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213182 [Multi-domain]  Cd Length: 182  Bit Score: 72.08  E-value: 2.23e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  12 FALRNISfrVPGRtlLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWS-SKAFARKVAYL 90
Cdd:cd03215    5 LEVRGLS--VKGA--VRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVTRRSpRDAIRAGIAYV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  91 PqqlppaegmtvrelvaigrypwhgalgrfgaADREKVeeaiSLVGLKPLAHRLV--DSLSGGERQRAWIAMLVAQDSRC 168
Cdd:cd03215   81 P-------------------------------EDRKRE----GLVLDLSVAENIAlsSLLSGGNQQKVVLARWLARDPRV 125

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 536036476 169 LLLDEPTSALDIAHQVDVLSLVHRLSqERGLTVIAVLHDINMAARYCDYLVALRGGEM 226
Cdd:cd03215  126 LILDEPTRGVDVGAKAEIYRLIRELA-DAGKAVLLISSELDELLGLCDRILVMYEGRI 182
PRK13651 PRK13651
cobalt transporter ATP-binding subunit; Provisional
 27-239 3.89e-15

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184210 [Multi-domain]  Cd Length: 305  Bit Score: 73.58  E-value: 3.89e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  27 LHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEI---LLDAQPLESWS-----------SKAFARKVAYLPQ 92
Cdd:PRK13651  23 LDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIewiFKDEKNKKKTKekekvleklviQKTRFKKIKKIKE 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  93 --------------QLPPAegmTVRELVAIGRYpwhgALGRFGAADREKVEEAISLVGLkPLAH--RLVDSLSGGERQRA 156
Cdd:PRK13651 103 irrrvgvvfqfaeyQLFEQ---TIEKDIIFGPV----SMGVSKEEAKKRAAKYIELVGL-DESYlqRSPFELSGGQKRRV 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 157 WIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQErGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIM 236
Cdd:PRK13651 175 ALAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNLNKQ-GKTIILVTHDLDNVLEWTKRTIFFKDGKIIKDGDTYDIL 253


                 ...
gi 536036476 237 RGE 239
Cdd:PRK13651 254 SDN 256
PLN03232 PLN03232
ABC transporter C family member; Provisional
 26-240 4.01e-15

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 75.01  E-value: 4.01e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   26 LLHPLSL-TFPAGKVtGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQQlPPAEGMTVRe 104
Cdd:PLN03232 1251 VLHGLSFfVSPSEKV-GVVGRTGAGKSSMLNALFRIVELEKGRIMIDDCDVAKFGLTDLRRVLSIIPQS-PVLFSGTVR- 1327

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  105 lVAIGRYPWHGALGRFGAADREKVEEAI--SLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIah 182
Cdd:PLN03232 1328 -FNIDPFSEHNDADLWEALERAHIKDVIdrNPFGLDAEVSEGGENFSVGQRQLLSLARALLRRSKILVLDEATASVDV-- 1404

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  183 QVDvlSLVHRLSQE--RGLTVIAVLHDINMAARyCDYLVALRGGEMIAQGTPAEIMRGET 240
Cdd:PLN03232 1405 RTD--SLIQRTIREefKSCTMLVIAHRLNTIID-CDKILVLSSGQVLEYDSPQELLSRDT 1461
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 23-180 4.51e-15

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 74.38  E-value: 4.51e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  23 GRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKML-GRHQPPSeGEILLDaqplESwsskafaRKVAYLPQQ---LPPAE 98
Cdd:PRK11819 336 DRLLIDDLSFSLPPGGIVGIIGPNGAGKSTLFKMItGQEQPDS-GTIKIG----ET-------VKLAYVDQSrdaLDPNK 403

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  99 gmTVRELVA-------IGRY--PWHGALGRFG--AADREKveeaislvglkplahrLVDSLSGGERQRAWIAMLVAQDSR 167
Cdd:PRK11819 404 --TVWEEISggldiikVGNReiPSRAYVGRFNfkGGDQQK----------------KVGVLSGGERNRLHLAKTLKQGGN 465

                        170
                 ....*....|...
gi 536036476 168 CLLLDEPTSALDI 180
Cdd:PRK11819 466 VLLLDEPTNDLDV 478
PTZ00243 PTZ00243
ABC transporter; Provisional
 19-237 5.17e-15

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 74.82  E-value: 5.17e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   19 FRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEIlldaqplesWSskafARKVAYLPQQlPPAE 98
Cdd:PTZ00243  668 FELEPKVLLRDVSVSVPRGKLTVVLGATGSGKSTLLQSLLSQFEISEGRV---------WA----ERSIAYVPQQ-AWIM 733

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   99 GMTVRelvaigrypwhGALGRFGAADREKVEEAISLVGLKPLAHRLVD-----------SLSGGERQRAWIAMLVAQDSR 167
Cdd:PTZ00243  734 NATVR-----------GNILFFDEEDAARLADAVRVSQLEADLAQLGGgleteigekgvNLSGGQKARVSLARAVYANRD 802

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 536036476  168 CLLLDEPTSALDiAHqvdvlsLVHRLSQE------RGLTVIAVLHDINMAARyCDYLVALRGGEMIAQGTPAEIMR 237
Cdd:PTZ00243  803 VYLLDDPLSALD-AH------VGERVVEEcflgalAGKTRVLATHQVHVVPR-ADYVVALGDGRVEFSGSSADFMR 870
PRK11000 PRK11000
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
43-235 5.90e-15

maltose/maltodextrin ABC transporter ATP-binding protein MalK;


Pssm-ID: 182893 [Multi-domain]  Cd Length: 369  Bit Score: 73.53  E-value: 5.90e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  43 IGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLeswsskafarkvaylpQQLPPAE---GM-----------TVRELVAI 108
Cdd:PRK11000  35 VGPSGCGKSTLLRMIAGLEDITSGDLFIGEKRM----------------NDVPPAErgvGMvfqsyalyphlSVAENMSF 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 109 GRypwhgALGRFGAADREK-VEEAISLVGLKPLAHRLVDSLSGGERQRAWIA-MLVAQdSRCLLLDEPTSALDIAHQVDV 186
Cdd:PRK11000  99 GL-----KLAGAKKEEINQrVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGrTLVAE-PSVFLLDEPLSNLDAALRVQM 172

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 536036476 187 LSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEmIAQ-GTPAEI 235
Cdd:PRK11000 173 RIEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGR-VAQvGKPLEL 221
SapD COG4170
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
31-237 1.72e-14

ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];


Pssm-ID: 443330 [Multi-domain]  Cd Length: 331  Bit Score: 71.86  E-value: 1.72e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  31 SLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPS----------EGEILLDAQPLESwsSKAFARKVAYLPQQ----LPP 96
Cdd:COG4170   27 SLTLNEGEIRGLVGESGSGKSLIAKAICGITKDNwhvtadrfrwNGIDLLKLSPRER--RKIIGREIAMIFQEpsscLDP 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  97 AEgmTV-RELV-AIgryPWHGALGRFGAADREKVEEAISL---VGLKplAHRLVDS-----LSGGERQRAWIAMLVAQDS 166
Cdd:COG4170  105 SA--KIgDQLIeAI---PSWTFKGKWWQRFKWRKKRAIELlhrVGIK--DHKDIMNsypheLTEGECQKVMIAMAIANQP 177

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 536036476 167 RCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMR 237
Cdd:COG4170  178 RLLIADEPTNAMESTTQAQIFRLLARLNQLQGTSILLISHDLESISQWADTITVLYCGQTVESGPTEQILK 248
GguA NF040905
sugar ABC transporter ATP-binding protein;
14-243 1.78e-14

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 72.51  E-value: 1.78e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKML-GRHQPPS-EGEILLDAQPLEswsskaF-------A 84
Cdd:NF040905   4 MRGITKTFPGVKALDDVNLSVREGEIHALCGENGAGKSTLMKVLsGVYPHGSyEGEILFDGEVCR------FkdirdseA 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  85 RKVAYLPQQLPPAEGMTVRELVAIGRYPwhgalGRFGAADREKV-EEAISL---VGLKPLAHRLVDSLSGGERQRAWIAM 160
Cdd:NF040905  78 LGIVIIHQELALIPYLSIAENIFLGNER-----AKRGVIDWNETnRRARELlakVGLDESPDTLVTDIGVGKQQLVEIAK 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 161 LVAQDSRCLLLDEPTSAL---DIAHqvdVLSLVHRLsQERGLTVIAVLHDINMAARYCDYLVALRGGEMIaqgtpaeimr 237
Cdd:NF040905 153 ALSKDVKLLILDEPTAALneeDSAA---LLDLLLEL-KAQGITSIIISHKLNEIRRVADSITVLRDGRTI---------- 218


                 ....*.
gi 536036476 238 gETLEM 243
Cdd:NF040905 219 -ETLDC 223
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 14-244 3.18e-14

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 72.01  E-value: 3.18e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWS-SKAFARKVAYLPQ 92
Cdd:PRK15439  14 ARSISKQYSGVEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCARLTpAKAHQLGIYLVPQ 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  93 QLPPAEGMTVRELVAIGrypwhgaLGRfGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLD 172
Cdd:PRK15439  94 EPLLFPNLSVKENILFG-------LPK-RQASMQKMKQLLAALGCQLDLDSSAGSLEVADRQIVEILRGLMRDSRILILD 165

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 536036476 173 EPTSALDIAHQVDVLSLVHRLsQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMRGETLEMI 244
Cdd:PRK15439 166 EPTASLTPAETERLFSRIREL-LAQGVGIVFISHKLPEIRQLADRISVMRDGTIALSGKTADLSTDDIIQAI 236
PRK10522 PRK10522
multidrug transporter membrane component/ATP-binding component; Provisional
 11-207 3.23e-14

multidrug transporter membrane component/ATP-binding component; Provisional


Pssm-ID: 236707 [Multi-domain]  Cd Length: 547  Bit Score: 71.93  E-value: 3.23e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  11 TFALRNISFRVPGRTL-LHPLSLTFPAGKVTGLIGHNGSGKSTLLKML-GRHQPPSeGEILLDAQPLESWSSKAFARKVA 88
Cdd:PRK10522 322 TLELRNVTFAYQDNGFsVGPINLTIKRGELLFLIGGNGSGKSTLAMLLtGLYQPQS-GEILLDGKPVTAEQPEDYRKLFS 400

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  89 ------YLPQQLPPAEGMTVR-ELVAIgrypWhgaLGRFGAADREKVEEaislvglkplaHRLVD-SLSGGERQRAWIAM 160
Cdd:PRK10522 401 avftdfHLFDQLLGPEGKPANpALVEK----W---LERLKMAHKLELED-----------GRISNlKLSKGQKKRLALLL 462

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 536036476 161 LVAQDSRCLLLDEPTSALD-----IAHQVdvlsLVHRLsQERGLTVIAVLHD 207
Cdd:PRK10522 463 ALAEERDILLLDEWAADQDphfrrEFYQV----LLPLL-QEMGKTIFAISHD 509
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 12-207 7.38e-14

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 70.75  E-value: 7.38e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  12 FALRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLK-MLGRHQPPSeGEILLDAQpLEswsskafarkVAYL 90
Cdd:PRK11147 320 FEMENVNYQIDGKQLVKDFSAQVQRGDKIALIGPNGCGKTTLLKlMLGQLQADS-GRIHCGTK-LE----------VAYF 387

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  91 PQ---QLPP--------AEGmtvRELVAIGRYPWH--GALGRFgaadrekveeaisLVGLKPlAHRLVDSLSGGERQRAW 157
Cdd:PRK11147 388 DQhraELDPektvmdnlAEG---KQEVMVNGRPRHvlGYLQDF-------------LFHPKR-AMTPVKALSGGERNRLL 450

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 536036476 158 IAMLVAQDSRCLLLDEPTSALDIahqvDVLSLVHRLSQERGLTVIAVLHD 207
Cdd:PRK11147 451 LARLFLKPSNLLILDEPTNDLDV----ETLELLEELLDSYQGTVLLVSHD 496
cbiO PRK13631
cobalt transporter ATP-binding subunit; Provisional
 25-241 1.18e-13

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237451 [Multi-domain]  Cd Length: 320  Bit Score: 69.49  E-value: 1.18e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  25 TLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILL------DAQPLESWSSKAFARKVAYLPQ------ 92
Cdd:PRK13631  40 VALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIQVgdiyigDKKNNHELITNPYSKKIKNFKElrrrvs 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  93 ---QLPPAEGM--TVRELVAIGRYpwhgALGRFGAADREKVEEAISLVGLK-PLAHRLVDSLSGGERQRAWIAMLVAQDS 166
Cdd:PRK13631 120 mvfQFPEYQLFkdTIEKDIMFGPV----ALGVKKSEAKKLAKFYLNKMGLDdSYLERSPFGLSGGQKRRVAIAGILAIQP 195

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 536036476 167 RCLLLDEPTSALDIAHQVDVLSLVhRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMRGETL 241
Cdd:PRK13631 196 EILIFDEPTAGLDPKGEHEMMQLI-LDAKANNKTVFVITHTMEHVLEVADEVIVMDKGKILKTGTPYEIFTDQHI 269
dppD PRK11022
dipeptide transporter ATP-binding subunit; Provisional
 30-237 1.40e-13

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 182906 [Multi-domain]  Cd Length: 326  Bit Score: 69.39  E-value: 1.40e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  30 LSLTFPAGKVTGLIGHNGSGKS-TLLKMLGRHQPP---SEGEILLDAQPLESWSSKA----FARKVAYLPQ----QLPPA 97
Cdd:PRK11022  26 ISYSVKQGEVVGIVGESGSGKSvSSLAIMGLIDYPgrvMAEKLEFNGQDLQRISEKErrnlVGAEVAMIFQdpmtSLNPC 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  98 E--GMTVRELVAIGRypwhgalGRFGAADREKVEEAISLVGLKPLAHRL---VDSLSGGERQRAWIAMLVAQDSRCLLLD 172
Cdd:PRK11022 106 YtvGFQIMEAIKVHQ-------GGNKKTRRQRAIDLLNQVGIPDPASRLdvyPHQLSGGMSQRVMIAMAIACRPKLLIAD 178

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 536036476 173 EPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMR 237
Cdd:PRK11022 179 EPTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAGQVVETGKAHDIFR 243
PRK15093 PRK15093
peptide ABC transporter ATP-binding protein SapD;
30-236 1.63e-13

peptide ABC transporter ATP-binding protein SapD;


Pssm-ID: 185049 [Multi-domain]  Cd Length: 330  Bit Score: 69.06  E-value: 1.63e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  30 LSLTFPAGKVTGLIGHNGSGKSTLLKML----GRHQPPSEGEILLDAQPLESWSSKAFARKVAY-------LPQQ-LPPA 97
Cdd:PRK15093  26 VSMTLTEGEIRGLVGESGSGKSLIAKAIcgvtKDNWRVTADRMRFDDIDLLRLSPRERRKLVGHnvsmifqEPQScLDPS 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  98 EGMTVRELVAIGRYPWHGA-LGRFGAADREKVEeAISLVGLK---PLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDE 173
Cdd:PRK15093 106 ERVGRQLMQNIPGWTYKGRwWQRFGWRKRRAIE-LLHRVGIKdhkDAMRSFPYELTEGECQKVMIAIALANQPRLLIADE 184

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 536036476 174 PTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIM 236
Cdd:PRK15093 185 PTNAMEPTTQAQIFRLLTRLNQNNNTTILLISHDLQMLSQWADKINVLYCGQTVETAPSKELV 247
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
9-248 1.81e-13

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 69.81  E-value: 1.81e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   9 DTTFALRNISFRVPGRtlLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSS-KAFARKV 87
Cdd:PRK09700 263 ETVFEVRNVTSRDRKK--VRDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDISPRSPlDAVKKGM 340

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  88 AYLPQ---------QLPPAEGMTVRELVAIGRypWHGALGRFGAADREKV-EEAISLVGLKplAHRL---VDSLSGGERQ 154
Cdd:PRK09700 341 AYITEsrrdngffpNFSIAQNMAISRSLKDGG--YKGAMGLFHEVDEQRTaENQRELLALK--CHSVnqnITELSGGNQQ 416

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 155 RAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQErGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAE 234
Cdd:PRK09700 417 KVLISKWLCCCPEVIIFDEPTRGIDVGAKAEIYKVMRQLADD-GKVILMVSSELPEIITVCDRIAVFCEGRLTQILTNRD 495

                        250
                 ....*....|....
gi 536036476 235 IMRGETLeMIYGIP 248
Cdd:PRK09700 496 DMSEEEI-MAWALP 508
ABCC_NFT1 cd03369
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...
 13-232 1.94e-13

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213269 [Multi-domain]  Cd Length: 207  Bit Score: 67.44  E-value: 1.94e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  13 ALRNISFRVPGRTllhplsltfpagKVtGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQ 92
Cdd:cd03369   23 VLKNVSFKVKAGE------------KI-GIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDISTIPLEDLRSSLTIIPQ 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  93 QlPPAEGMTVRElvaigrypwhgALGRFGAADREKVEEAISLVGLKplahrlvDSLSGGERQRAWIAMLVAQDSRCLLLD 172
Cdd:cd03369   90 D-PTLFSGTIRS-----------NLDPFDEYSDEEIYGALRVSEGG-------LNLSQGQRQLLCLARALLKRPRVLVLD 150

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 173 EPTSALDIAHQVDVLSLVHRLSQerGLTVIAVLHDINMAARyCDYLVALRGGEMIAQGTP 232
Cdd:cd03369  151 EATASIDYATDALIQKTIREEFT--NSTILTIAHRLRTIID-YDKILVMDAGEVKEYDHP 207
MK0520 COG2401
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...
 16-206 2.93e-13

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];


Pssm-ID: 441957 [Multi-domain]  Cd Length: 222  Bit Score: 66.91  E-value: 2.93e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  16 NISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQP--PSEGEILLDAQPLeswsskafarkvaylPQQ 93
Cdd:COG2401   35 GVELRVVERYVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALKgtPVAGCVDVPDNQF---------------GRE 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  94 LPPAEgmtvrelvaigrypwhgALGRFGAADrEKVEeAISLVGLK--PLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLL 171
Cdd:COG2401  100 ASLID-----------------AIGRKGDFK-DAVE-LLNAVGLSdaVLWLRRFKELSTGQKFRFRLALLLAERPKLLVI 160

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 536036476 172 DEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLH 206
Cdd:COG2401  161 DEFCSHLDRQTAKRVARNLQKLARRAGITLVVATH 195
PRK10789 PRK10789
SmdA family multidrug ABC transporter permease/ATP-binding protein;
18-231 3.41e-13

SmdA family multidrug ABC transporter permease/ATP-binding protein;


Pssm-ID: 182732 [Multi-domain]  Cd Length: 569  Bit Score: 68.97  E-value: 3.41e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  18 SFRVPG--RTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQP-----LESWSSKaFArkvayL 90
Cdd:PRK10789 320 QFTYPQtdHPALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIPltklqLDSWRSR-LA-----V 393

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  91 PQQLPPAEGMTVRELVAIGRyPwhgalgrfgAADREKVEEAISLVGLKPLAHRLVDS-----------LSGGERQRAWIA 159
Cdd:PRK10789 394 VSQTPFLFSDTVANNIALGR-P---------DATQQEIEHVARLASVHDDILRLPQGydtevgergvmLSGGQKQRISIA 463

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 536036476 160 MLVAQDSRCLLLDEPTSALD--IAHQVdvlslVHRLSQ-ERGLTVIAVLHDINmAARYCDYLVALRGGEMIAQGT 231
Cdd:PRK10789 464 RALLLNAEILILDDALSAVDgrTEHQI-----LHNLRQwGEGRTVIISAHRLS-ALTEASEILVMQHGHIAQRGN 532
oppD PRK09473
oligopeptide transporter ATP-binding component; Provisional
 25-257 3.67e-13

oligopeptide transporter ATP-binding component; Provisional


Pssm-ID: 181888 [Multi-domain]  Cd Length: 330  Bit Score: 68.21  E-value: 3.67e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  25 TLLHPLSLTFPAGKVTGLIGHNGSGKS-TLLKMLGrhqppsegeiLLDAQPLESWSSKAFARKVAYLPQ-QLppaEGMTV 102
Cdd:PRK09473  30 TAVNDLNFSLRAGETLGIVGESGSGKSqTAFALMG----------LLAANGRIGGSATFNGREILNLPEkEL---NKLRA 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 103 RELVAIGRYPW-------------------HGALGRFGA-------ADREKVEEAISLVGLKPlaHRLvdslSGGERQRA 156
Cdd:PRK09473  97 EQISMIFQDPMtslnpymrvgeqlmevlmlHKGMSKAEAfeesvrmLDAVKMPEARKRMKMYP--HEF----SGGMRQRV 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 157 WIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIM 236
Cdd:PRK09473 171 MIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGNARDVF 250

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 536036476 237 --------------------RGETLEMIYGIPMGILPHPAG 257
Cdd:PRK09473 251 yqpshpysigllnavprldaEGESLLTIPGNPPNLLRLPKG 291
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 16-237 4.56e-13

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 68.73  E-value: 4.56e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  16 NISFRVPGRTL--LHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWS---------SKAFA 84
Cdd:PRK10261  19 NIAFMQEQQKIaaVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQAGGLVQCDKMLLRRRSrqvielseqSAAQM 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  85 RKVAYLPQQLPPAEGMT-------VRELVAIGRYPWHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAW 157
Cdd:PRK10261  99 RHVRGADMAMIFQEPMTslnpvftVGEQIAESIRLHQGASREEAMVEAKRMLDQVRIPEAQTILSRYPHQLSGGMRQRVM 178

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 158 IAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMR 237
Cdd:PRK10261 179 IAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVLVMYQGEAVETGSVEQIFH 258
ugpC PRK11650
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
14-235 5.05e-13

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;


Pssm-ID: 236947 [Multi-domain]  Cd Length: 356  Bit Score: 67.95  E-value: 5.05e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTL-LHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAqpleswsskafaRKVaylpQ 92
Cdd:PRK11650   6 LQAVRKSYDGKTQvIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGG------------RVV----N 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  93 QLPPAE--------------GMTVRELVAIG---RypwhgalgRFGAAD-REKVEEAISLVGLKPLAHRLVDSLSGGERQ 154
Cdd:PRK11650  70 ELEPADrdiamvfqnyalypHMSVRENMAYGlkiR--------GMPKAEiEERVAEAARILELEPLLDRKPRELSGGQRQ 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 155 RawIAMLVA--QDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGeMIAQ-GT 231
Cdd:PRK11650 142 R--VAMGRAivREPAVFLFDEPLSNLDAKLRVQMRLEIQRLHRRLKTTSLYVTHDQVEAMTLADRVVVMNGG-VAEQiGT 218


                 ....
gi 536036476 232 PAEI 235
Cdd:PRK11650 219 PVEV 222
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 13-230 5.98e-13

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 68.34  E-value: 5.98e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  13 ALRNISFRV-PGRTLlhplsltfpagkvtGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSS---KAFARKVA 88
Cdd:PRK10261 339 AVEKVSFDLwPGETL--------------SLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTLSPgklQALRRDIQ 404

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  89 YLPQ----QLPPAE--GMTVRELVAIgrypwHGALGrfGAADREKVEEAISLVGLKP-LAHRLVDSLSGGERQRAWIAML 161
Cdd:PRK10261 405 FIFQdpyaSLDPRQtvGDSIMEPLRV-----HGLLP--GKAAAARVAWLLERVGLLPeHAWRYPHEFSGGQRQRICIARA 477

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 536036476 162 VAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQG 230
Cdd:PRK10261 478 LALNPKVIIADEAVSALDVSIRGQIINLLLDLQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVEIG 546
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
 23-226 6.31e-13

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 68.40  E-value: 6.31e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476    23 GRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRhQPPSEGEILLDAQPLESWSSKAFARKVAYLPQQLPPAEGMTV 102
Cdd:TIGR01271 1231 GRAVLQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLR-LLSTEGEIQIDGVSWNSVTLQTWRKAFGVIPQKVFIFSGTFR 1309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   103 RELVAIGRYpwhgalgrfgaADRE--KVEEAislVGLKP--------LAHRLVDS---LSGGERQRAWIAMLVAQDSRCL 169
Cdd:TIGR01271 1310 KNLDPYEQW-----------SDEEiwKVAEE---VGLKSvieqfpdkLDFVLVDGgyvLSNGHKQLMCLARSILSKAKIL 1375

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 536036476   170 LLDEPTSALD-IAHQVDVLSLVHRLSQergLTVIAVLHDINmAARYCDYLVALRGGEM 226
Cdd:TIGR01271 1376 LLDEPSAHLDpVTLQIIRKTLKQSFSN---CTVILSEHRVE-ALLECQQFLVIEGSSV 1429
PRK14243 PRK14243
phosphate transporter ATP-binding protein; Provisional
 5-217 6.80e-13

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184588 [Multi-domain]  Cd Length: 264  Bit Score: 66.73  E-value: 6.80e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   5 TNHSDTTFALRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQP--PS---EGEILL--------D 71
Cdd:PRK14243   4 LNGTETVLRTENLNVYYGSFLAVKNVWLDIPKNQITAFIGPSGCGKSTILRCFNRLNDliPGfrvEGKVTFhgknlyapD 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  72 AQPLEswsskaFARKVAYLPQQlPPAEGMTVRELVAIGRYpwhgALGRFGAADrEKVEEAISLVGL-KPLAHRLVDS--- 147
Cdd:PRK14243  84 VDPVE------VRRRIGMVFQK-PNPFPKSIYDNIAYGAR----INGYKGDMD-ELVERSLRQAALwDEVKDKLKQSgls 151

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 148 LSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQErgLTVIAVLHDINMAARYCDY 217
Cdd:PRK14243 152 LSGGQQQRLCIARAIAVQPEVILMDEPCSALDPISTLRIEELMHELKEQ--YTIIIVTHNMQQAARVSDM 219
ABCC_SUR1_N cd03290
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ...
 22-224 1.29e-12

ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213257 [Multi-domain]  Cd Length: 218  Bit Score: 65.43  E-value: 1.29e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  22 PGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLL-KMLGRHQPPSEGEILLDAQPLESWSSKAFARK---VAYLPQQlPPA 97
Cdd:cd03290   12 SGLATLSNINIRIPTGQLTMIVGQVGCGKSSLLlAILGEMQTLEGKVHWSNKNESEPSFEATRSRNrysVAYAAQK-PWL 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  98 EGMTVRELVAIGrypwhgalGRFGAADREKVEEAISL---VGLKP------LAHRLVDsLSGGERQRAWIAMLVAQDSRC 168
Cdd:cd03290   91 LNATVEENITFG--------SPFNKQRYKAVTDACSLqpdIDLLPfgdqteIGERGIN-LSGGQRQRICVARALYQNTNI 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 536036476 169 LLLDEPTSALDIaHQVDVL--SLVHRLSQERGLTVIAVLHDINMAArYCDYLVALRGG 224
Cdd:cd03290  162 VFLDDPFSALDI-HLSDHLmqEGILKFLQDDKRTLVLVTHKLQYLP-HADWIIAMKDG 217
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 9-181 1.92e-12

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 66.59  E-value: 1.92e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   9 DTTFALRNISFRVP-GRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAF-ARK 86
Cdd:COG3845  255 EVVLEVENLSVRDDrGVPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLDGEDITGLSPRERrRLG 334

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  87 VAYLPQQlPPAEG----MTVRELVAIGRYpWHGALGRFGAADREKVEE-AISLVG----LKPLAHRLVDSLSGGERQRAW 157
Cdd:COG3845  335 VAYIPED-RLGRGlvpdMSVAENLILGRY-RRPPFSRGGFLDRKAIRAfAEELIEefdvRTPGPDTPARSLSGGNQQKVI 412

                        170       180
                 ....*....|....*....|....
gi 536036476 158 IAMLVAQDSRCLLLDEPTSALDIA 181
Cdd:COG3845  413 LARELSRDPKLLIAAQPTRGLDVG 436
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
 14-238 2.96e-12

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 66.51  E-value: 2.96e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476    14 LRNISFRV-PGRTL-LHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLP 91
Cdd:TIGR00957 1287 FRNYCLRYrEDLDLvLRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGLNIAKIGLHDLRFKITIIP 1366

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476    92 QQlPPAEGMTVRElvaigrypwhgALGRFGAADREKVEEAISLVGLKPLAHRLVD-----------SLSGGERQRAWIAM 160
Cdd:TIGR00957 1367 QD-PVLFSGSLRM-----------NLDPFSQYSDEEVWWALELAHLKTFVSALPDkldhecaeggeNLSVGQRQLVCLAR 1434

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   161 LVAQDSRCLLLDEPTSALDIahQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVaLRGGEMIAQGTPAEIM--RG 238
Cdd:TIGR00957 1435 ALLRKTKILVLDEATAAVDL--ETDNLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIV-LDKGEVAEFGAPSNLLqqRG 1511
ycf16 CHL00131
sulfate ABC transporter protein; Validated
 5-180 5.30e-12

sulfate ABC transporter protein; Validated


Pssm-ID: 214372 [Multi-domain]  Cd Length: 252  Bit Score: 63.89  E-value: 5.30e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   5 TNHSDTTFALRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHqpPS----EGEILLDAQPLESWSS 80
Cdd:CHL00131   1 MNKNKPILEIKNLHASVNENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAGH--PAykilEGDILFKGESILDLEP 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  81 KAFARKVAYLPQQLP---PaeGMTVRELVaigRYPWHGALGRFGAADREKVE------EAISLVGLKP-LAHRLV-DSLS 149
Cdd:CHL00131  79 EERAHLGIFLAFQYPieiP--GVSNADFL---RLAYNSKRKFQGLPELDPLEfleiinEKLKLVGMDPsFLSRNVnEGFS 153

                        170       180       190
                 ....*....|....*....|....*....|.
gi 536036476 150 GGERQRAWIAMLVAQDSRCLLLDEPTSALDI 180
Cdd:CHL00131 154 GGEKKRNEILQMALLDSELAILDETDSGLDI 184
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 22-204 6.36e-12

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 65.23  E-value: 6.36e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   22 PGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKML-GRHQPPSEGEILLDAQPLESWS-SKAFARKVAYLPQ------- 92
Cdd:TIGR02633 271 PHRKRVDDVSFSLRRGEILGVAGLVGAGRTELVQALfGAYPGKFEGNVFINGKPVDIRNpAQAIRAGIAMVPEdrkrhgi 350

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   93 --QLPPAEGMTvreLVAIGRYPWHGALGrfGAADREKVEEAISLVGLKPLAHRL-VDSLSGGERQRAWIAMLVAQDSRCL 169
Cdd:TIGR02633 351 vpILGVGKNIT---LSVLKSFCFKMRID--AAAELQIIGSAIQRLKVKTASPFLpIGRLSGGNQQKAVLAKMLLTNPRVL 425

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 536036476  170 LLDEPTSALDIAHQVDVLSLVHRLSQErGLTVIAV 204
Cdd:TIGR02633 426 ILDEPTRGVDVGAKYEIYKLINQLAQE-GVAIIVV 459
ABC_RNaseL_inhibitor cd03222
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ...
 34-223 9.92e-12

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213189 [Multi-domain]  Cd Length: 177  Bit Score: 61.82  E-value: 9.92e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  34 FPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQpleswsskafarKVAYLPQQLppaegmtvrelvaigrypw 113
Cdd:cd03222   22 VKEGEVIGIVGPNGTGKTTAVKILAGQLIPNGDNDEWDGI------------TPVYKPQYI------------------- 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 114 hgalgrfgaadrekveeaislvglkplahrlvdSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRL 193
Cdd:cd03222   71 ---------------------------------DLSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRL 117

                        170       180       190
                 ....*....|....*....|....*....|
gi 536036476 194 SQERGLTVIAVLHDINMAARYCDYLVALRG 223
Cdd:cd03222  118 SEEGKKTALVVEHDLAVLDYLSDRIHVFEG 147
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
 9-204 1.27e-11

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 64.18  E-value: 1.27e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   9 DTTFALRNISFR---VPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKML-GRHQPPSEGEILLDAQPLE-SWSSKAF 83
Cdd:PRK13549 257 EVILEVRNLTAWdpvNPHIKRVDDVSFSLRRGEILGIAGLVGAGRTELVQCLfGAYPGRWEGEIFIDGKPVKiRNPQQAI 336

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  84 ARKVAYLPQ---------QLPPAEGMTvreLVAIGRYPWHGALGrfGAADREKVEEAISLVGLKPLAHRL-VDSLSGGER 153
Cdd:PRK13549 337 AQGIAMVPEdrkrdgivpVMGVGKNIT---LAALDRFTGGSRID--DAAELKTILESIQRLKVKTASPELaIARLSGGNQ 411

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 536036476 154 QRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQErGLTVIAV 204
Cdd:PRK13549 412 QKAVLAKCLLLNPKILILDEPTRGIDVGAKYEIYKLINQLVQQ-GVAIIVI 461
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 6-204 1.84e-11

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 63.48  E-value: 1.84e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   6 NHSDTTFALRNISfrVPGrtlLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSK-AFA 84
Cdd:PRK10762 252 APGEVRLKVDNLS--GPG---VNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVTRSPQdGLA 326

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  85 RKVAYLpqqlppAE---------GMTVRE---LVAIgRYPWHGALGRFGAADREKVEEAISLVGLK-PLAHRLVDSLSGG 151
Cdd:PRK10762 327 NGIVYI------SEdrkrdglvlGMSVKEnmsLTAL-RYFSRAGGSLKHADEQQAVSDFIRLFNIKtPSMEQAIGLLSGG 399

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 536036476 152 ERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQErGLTVIAV 204
Cdd:PRK10762 400 NQQKVAIARGLMTRPKVLILDEPTRGVDVGAKKEIYQLINQFKAE-GLSIILV 451
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 28-180 3.15e-11

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 63.05  E-value: 3.15e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  28 HPL----SLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLdAQPLeswsskafarKVAYLPQQLPPAEGMTVR 103
Cdd:PRK11147  16 APLldnaELHIEDNERVCLVGRNGAGKSTLMKILNGEVLLDDGRIIY-EQDL----------IVARLQQDPPRNVEGTVY 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 104 ELVAIG---------RYpwHGALGRFGAADREK-----------------------VEEAISLVGLKPlaHRLVDSLSGG 151
Cdd:PRK11147  85 DFVAEGieeqaeylkRY--HDISHLVETDPSEKnlnelaklqeqldhhnlwqlenrINEVLAQLGLDP--DAALSSLSGG 160

                        170       180
                 ....*....|....*....|....*....
gi 536036476 152 ERQRAWIAMLVAQDSRCLLLDEPTSALDI 180
Cdd:PRK11147 161 WLRKAALGRALVSNPDVLLLDEPTNHLDI 189
PRK13540 PRK13540
cytochrome c biogenesis protein CcmA; Provisional
 16-197 5.00e-11

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184127 [Multi-domain]  Cd Length: 200  Bit Score: 60.35  E-value: 5.00e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  16 NISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESwSSKAFARKVAYLPQQLP 95
Cdd:PRK13540   6 ELDFDYHDQPLLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSIKK-DLCTYQKQLCFVGHRSG 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  96 PAEGMTVRELVAIGRYPWHGALGrfgaadrekVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPT 175
Cdd:PRK13540  85 INPYLTLRENCLYDIHFSPGAVG---------ITELCRLFSLEHLIDYPCGLLSSGQKRQVALLRLWMSKAKLWLLDEPL 155

                        170       180
                 ....*....|....*....|..
gi 536036476 176 SALDiahQVDVLSLVHRLSQER 197
Cdd:PRK13540 156 VALD---ELSLLTIITKIQEHR 174
PLN03140 PLN03140
ABC transporter G family member; Provisional
 26-248 8.16e-11

ABC transporter G family member; Provisional


Pssm-ID: 215599 [Multi-domain]  Cd Length: 1470  Bit Score: 62.17  E-value: 8.16e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   26 LLHPLSLTFPAGKVTGLIGHNGSGKSTLLKML-GRHQPPS-EGEILLDAQPLESwssKAFARKVAYLPQQLPPAEGMTVR 103
Cdd:PLN03140  895 LLREVTGAFRPGVLTALMGVSGAGKTTLMDVLaGRKTGGYiEGDIRISGFPKKQ---ETFARISGYCEQNDIHSPQVTVR 971

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  104 ELV---AIGRYPWHgalgrfgAADREK---VEEAISLVGLKPLAHRLV-----DSLSGGERQRAWIAM-LVAQDSrCLLL 171
Cdd:PLN03140  972 ESLiysAFLRLPKE-------VSKEEKmmfVDEVMELVELDNLKDAIVglpgvTGLSTEQRKRLTIAVeLVANPS-IIFM 1043

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  172 DEPTSALDIAHQVDVLSLVhRLSQERGLTVIAVLH--DINMAARYCDYLVALRGGEMIAQGT----PAEIMrgETLEMIY 245
Cdd:PLN03140 1044 DEPTSGLDARAAAIVMRTV-RNTVDTGRTVVCTIHqpSIDIFEAFDELLLMKRGGQVIYSGPlgrnSHKII--EYFEAIP 1120


                  ...
gi 536036476  246 GIP 248
Cdd:PLN03140 1121 GVP 1123
sufC PRK09580
cysteine desulfurase ATPase component; Reviewed
 13-190 1.44e-10

cysteine desulfurase ATPase component; Reviewed


Pssm-ID: 181965 [Multi-domain]  Cd Length: 248  Bit Score: 59.80  E-value: 1.44e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  13 ALRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKML-GRHQ-PPSEGEILLDAQPLESWSSKAFARKVAYL 90
Cdd:PRK09580   3 SIKDLHVSVEDKAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLaGREDyEVTGGTVEFKGKDLLELSPEDRAGEGIFM 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  91 PQQLP-PAEGMTVR-----ELVAIGRYPWHGALGRFGAADRekVEEAISLVGLKP-LAHRLVD-SLSGGERQRAWIAMLV 162
Cdd:PRK09580  83 AFQYPvEIPGVSNQfflqtALNAVRSYRGQEPLDRFDFQDL--MEEKIALLKMPEdLLTRSVNvGFSGGEKKRNDILQMA 160

                        170       180
                 ....*....|....*....|....*...
gi 536036476 163 AQDSRCLLLDEPTSALDIahqvDVLSLV 190
Cdd:PRK09580 161 VLEPELCILDESDSGLDI----DALKIV 184
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
 24-180 2.29e-10

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 60.57  E-value: 2.29e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  24 RTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLdaqpleswsskAFARKVAYLPQ-QLP--PAEGM 100
Cdd:PRK10636 325 RIILDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIGL-----------AKGIKLGYFAQhQLEflRADES 393

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 101 TVRELVAIG----RYPWHGALGRFGAADrEKVEEAislvglkplahrlVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTS 176
Cdd:PRK10636 394 PLQHLARLApqelEQKLRDYLGGFGFQG-DKVTEE-------------TRRFSGGEKARLVLALIVWQRPNLLLLDEPTN 459


                 ....
gi 536036476 177 ALDI 180
Cdd:PRK10636 460 HLDL 463
ABC_UvrA_II cd03271
ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair ...
 147-232 2.83e-10

ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213238 [Multi-domain]  Cd Length: 261  Bit Score: 59.17  E-value: 2.83e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 147 SLSGGERQRAWIAMLVAQDS--RCL-LLDEPTSAL---DIAHQVDVLslvHRLSqERGLTVIAVLHDINMAaRYCDYLVA 220
Cdd:cd03271  169 TLSGGEAQRIKLAKELSKRStgKTLyILDEPTTGLhfhDVKKLLEVL---QRLV-DKGNTVVVIEHNLDVI-KCADWIID 243

                         90
                 ....*....|....*...
gi 536036476 221 L------RGGEMIAQGTP 232
Cdd:cd03271  244 LgpeggdGGGQVVASGTP 261
PLN03211 PLN03211
ABC transporter G-25; Provisional
 24-206 8.14e-10

ABC transporter G-25; Provisional


Pssm-ID: 215634 [Multi-domain]  Cd Length: 659  Bit Score: 58.74  E-value: 8.14e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  24 RTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKML-GRHQPPS-EGEILLDAQPLeswsSKAFARKVAYLPQQLPPAEGMT 101
Cdd:PLN03211  81 RTILNGVTGMASPGEILAVLGPSGSGKSTLLNALaGRIQGNNfTGTILANNRKP----TKQILKRTGFVTQDDILYPHLT 156

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 102 VRE---LVAIGRYPwhGALGRfgaadREKV---EEAISLVGLKP-----LAHRLVDSLSGGERQRAWIAMLVAQDSRCLL 170
Cdd:PLN03211 157 VREtlvFCSLLRLP--KSLTK-----QEKIlvaESVISELGLTKcentiIGNSFIRGISGGERKRVSIAHEMLINPSLLI 229

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 536036476 171 LDEPTSALDIAHQVDVLSLVHRLSQeRGLTVIAVLH 206
Cdd:PLN03211 230 LDEPTSGLDATAAYRLVLTLGSLAQ-KGKTIVTSMH 264
ABCC_CFTR2 cd03289
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ...
 23-208 8.60e-10

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213256 [Multi-domain]  Cd Length: 275  Bit Score: 57.94  E-value: 8.60e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  23 GRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRhQPPSEGEILLD-----AQPLESWsSKAFarkvAYLPQQlppa 97
Cdd:cd03289   16 GNAVLENISFSISPGQRVGLLGRTGSGKSTLLSAFLR-LLNTEGDIQIDgvswnSVPLQKW-RKAF----GVIPQK---- 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  98 egmtvrelVAIGRYPWHGALGRFGAADREKVEEAISLVGLK--------PLAHRLVDS---LSGGERQRAWIAMLVAQDS 166
Cdd:cd03289   86 --------VFIFSGTFRKNLDPYGKWSDEEIWKVAEEVGLKsvieqfpgQLDFVLVDGgcvLSHGHKQLMCLARSVLSKA 157

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 536036476 167 RCLLLDEPTSALD-IAHQVDVLSLVHRLSqerGLTVIAVLHDI 208
Cdd:cd03289  158 KILLLDEPSAHLDpITYQVIRKTLKQAFA---DCTVILSEHRI 197
uvra TIGR00630
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ...
 135-237 1.01e-09

excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273184 [Multi-domain]  Cd Length: 925  Bit Score: 58.87  E-value: 1.01e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  135 VGLKPLA-HRLVDSLSGGERQRAWIAMLVAQDSRCLL--LDEPTSALdiaHQVDVLSLVHRLSQERGL--TVIAVLHDIN 209
Cdd:TIGR00630 475 VGLDYLSlSRAAGTLSGGEAQRIRLATQIGSGLTGVLyvLDEPSIGL---HQRDNRRLINTLKRLRDLgnTLIVVEHDED 551

                          90       100       110
                  ....*....|....*....|....*....|....
gi 536036476  210 MAaRYCDYLVAL------RGGEMIAQGTPAEIMR 237
Cdd:TIGR00630 552 TI-RAADYVIDIgpgageHGGEVVASGTPEEILA 584
PLN03130 PLN03130
ABC transporter C family member; Provisional
 24-236 1.02e-09

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 58.98  E-value: 1.02e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   24 RTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLK-MLGRHQPPSEGEILLDAqpleswsskafarKVAYLPQqLPPAEGMTV 102
Cdd:PLN03130  630 RPTLSNINLDVPVGSLVAIVGSTGEGKTSLISaMLGELPPRSDASVVIRG-------------TVAYVPQ-VSWIFNATV 695

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  103 RELVAigrypwhgalgrFGAA-DREKVEEAISLVGLK------------PLAHRLVDsLSGGERQRAWIAMLVAQDSRCL 169
Cdd:PLN03130  696 RDNIL------------FGSPfDPERYERAIDVTALQhdldllpggdltEIGERGVN-ISGGQKQRVSMARAVYSNSDVY 762

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 536036476  170 LLDEPTSALD--IAHQVDVLSLVHRLSQERGLTVIAVLHDINmaarYCDYLVALRGGEMIAQGTPAEIM 236
Cdd:PLN03130  763 IFDDPLSALDahVGRQVFDKCIKDELRGKTRVLVTNQLHFLS----QVDRIILVHEGMIKEEGTYEELS 827
UvrA COG0178
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];
148-237 1.42e-09

Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];


Pssm-ID: 439948 [Multi-domain]  Cd Length: 941  Bit Score: 58.11  E-value: 1.42e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 148 LSGGERQRAWIAM-LVAQDS-RCL-LLDEPTSAL---DIAHQVDVLslvHRLSqERGLTVIAVLHD---INMAarycDYL 218
Cdd:COG0178  827 LSGGEAQRVKLASeLSKRSTgKTLyILDEPTTGLhfhDIRKLLEVL---HRLV-DKGNTVVVIEHNldvIKTA----DWI 898

                         90       100
                 ....*....|....*....|....*
gi 536036476 219 VAL------RGGEMIAQGTPAEIMR 237
Cdd:COG0178  899 IDLgpeggdGGGEIVAEGTPEEVAK 923
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
 14-236 2.04e-09

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 57.33  E-value: 2.04e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGE--------ILLDAQPLESWSSKAFAR 85
Cdd:PRK10938   6 ISQGTFRLSDTKTLQLPSLTLNAGDSWAFVGANGSGKSALARALAGELPLLSGErqsqfshiTRLSFEQLQKLVSDEWQR 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  86 KVAYLpqqLPPAE---GMTVRELVaigrypwhgalgRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIA-ML 161
Cdd:PRK10938  86 NNTDM---LSPGEddtGRTTAEII------------QDEVKDPARCEQLAQQFGITALLDRRFKYLSTGETRKTLLCqAL 150

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 536036476 162 VAQDSrCLLLDEPTSALDIAHQVDVLSLVHRLSQErGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIM 236
Cdd:PRK10938 151 MSEPD-LLILDEPFDGLDVASRQQLAELLASLHQS-GITLVLVLNRFDEIPDFVQFAGVLADCTLAETGEREEIL 223
PLN03232 PLN03232
ABC transporter C family member; Provisional
 27-241 2.38e-09

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 57.68  E-value: 2.38e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   27 LHPLSLTFPAGKVTGLIGHNGSGKSTLLK-MLGRhQPPSEGeilldaqpleswSSKAFARKVAYLPQqLPPAEGMTVREL 105
Cdd:PLN03232  633 LSDINLEIPVGSLVAIVGGTGEGKTSLISaMLGE-LSHAET------------SSVVIRGSVAYVPQ-VSWIFNATVREN 698

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  106 VAIGRYPWHGALGRfgAADREKVEEAISLVG---LKPLAHRLVDsLSGGERQRAWIAMLVAQDSRCLLLDEPTSALD--I 180
Cdd:PLN03232  699 ILFGSDFESERYWR--AIDVTALQHDLDLLPgrdLTEIGERGVN-ISGGQKQRVSMARAVYSNSDIYIFDDPLSALDahV 775

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 536036476  181 AHQVDVLSLVHRLSQERGLTVIAVLHDINMAarycDYLVALRGGEMIAQGTPAEIMRGETL 241
Cdd:PLN03232  776 AHQVFDSCMKDELKGKTRVLVTNQLHFLPLM----DRIILVSEGMIKEEGTFAELSKSGSL 832
uvrA PRK00349
excinuclease ABC subunit UvrA;
135-237 8.43e-09

excinuclease ABC subunit UvrA;


Pssm-ID: 234734 [Multi-domain]  Cd Length: 943  Bit Score: 55.85  E-value: 8.43e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 135 VGLKPLA-HRLVDSLSGGERQRAWIA----------MLVaqdsrcllLDEPTSALdiaHQVDVLSLVHRLSQERGL--TV 201
Cdd:PRK00349 476 VGLDYLTlSRSAGTLSGGEAQRIRLAtqigsgltgvLYV--------LDEPSIGL---HQRDNDRLIETLKHLRDLgnTL 544

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 536036476 202 IAVLHD---InMAArycDYLVAL------RGGEMIAQGTPAEIMR 237
Cdd:PRK00349 545 IVVEHDedtI-RAA---DYIVDIgpgagvHGGEVVASGTPEEIMK 585
uvra TIGR00630
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ...
 147-235 9.06e-09

excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273184 [Multi-domain]  Cd Length: 925  Bit Score: 55.79  E-value: 9.06e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  147 SLSGGERQRAWIAM-LVAQDS-RCL-LLDEPTSAL---DIAHQVDVL-SLVHRlsqerGLTVIAVLH--DINMAArycDY 217
Cdd:TIGR00630 829 TLSGGEAQRIKLAKeLSKRSTgRTLyILDEPTTGLhfdDIKKLLEVLqRLVDK-----GNTVVVIEHnlDVIKTA---DY 900

                          90       100
                  ....*....|....*....|....
gi 536036476  218 LVAL------RGGEMIAQGTPAEI 235
Cdd:TIGR00630 901 IIDLgpeggdGGGTVVASGTPEEV 924
3a01203 TIGR00954
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ...
 14-206 1.10e-08

Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 273360 [Multi-domain]  Cd Length: 659  Bit Score: 55.53  E-value: 1.10e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   14 LRNISFRVP-GRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQpleswsskafaRKVAYLPQ 92
Cdd:TIGR00954 454 FENIPLVTPnGDVLIESLSFEVPSGNNLLICGPNGCGKSSLFRILGELWPVYGGRLTKPAK-----------GKLFYVPQ 522

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   93 QlPPAEGMTVRELVAigrYPwHGALGRFGAADREKVEEAI-SLVGLKPLAHRLV---------DSLSGGERQRAWIAMLV 162
Cdd:TIGR00954 523 R-PYMTLGTLRDQII---YP-DSSEDMKRRGLSDKDLEQIlDNVQLTHILEREGgwsavqdwmDVLSGGEKQRIAMARLF 597

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 536036476  163 AQDSRCLLLDEPTSALdiahQVDVLSLVHRLSQERGLTVIAVLH 206
Cdd:TIGR00954 598 YHKPQFAILDECTSAV----SVDVEGYMYRLCREFGITLFSVSH 637
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 30-226 1.37e-08

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 55.06  E-value: 1.37e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  30 LSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKA-FARKVAYLP---QQ----LPPAEGMT 101
Cdd:PRK15439 282 ISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEINALSTAQrLARGLVYLPedrQSsglyLDAPLAWN 361

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 102 VRELVaigrypwHGALGRF--GAADREKVEEAISLVGLKpLAH--RLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSA 177
Cdd:PRK15439 362 VCALT-------HNRRGFWikPARENAVLERYRRALNIK-FNHaeQAARTLSGGNQQKVLIAKCLEASPQLLIVDEPTRG 433

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 536036476 178 LDIAHQVDVLSLVHRLSQErGLTVIAVLHDINMAARYCDYLVALRGGEM 226
Cdd:PRK15439 434 VDVSARNDIYQLIRSIAAQ-NVAVLFISSDLEEIEQMADRVLVMHQGEI 481
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
 27-236 1.38e-08

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 55.34  E-value: 1.38e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476    27 LHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQpleswsskafarkVAYLPQQlPPAEGMTVRELV 106
Cdd:TIGR00957  654 LNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVHMKGS-------------VAYVPQQ-AWIQNDSLRENI 719

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   107 AigrypwhgalgrFGAADREK----VEEAISLVG---LKPLAHRLVD-----SLSGGERQRAWIAMLVAQDSRCLLLDEP 174
Cdd:TIGR00957  720 L------------FGKALNEKyyqqVLEACALLPdleILPSGDRTEIgekgvNLSGGQKQRVSLARAVYSNADIYLFDDP 787

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 536036476   175 TSALDiAHqVDVLSLVHRLSQE---RGLTVIAVLHDINMAARyCDYLVALRGGEMIAQGTPAEIM 236
Cdd:TIGR00957  788 LSAVD-AH-VGKHIFEHVIGPEgvlKNKTRILVTHGISYLPQ-VDVIIVMSGGKISEMGSYQELL 849
UvrA COG0178
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];
135-237 1.45e-08

Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];


Pssm-ID: 439948 [Multi-domain]  Cd Length: 941  Bit Score: 55.03  E-value: 1.45e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 135 VGLKPLA-HRLVDSLSGGERQRAWIA----------MLVaqdsrcllLDEPTSALdiaHQVD---VLSLVHRLsQERGLT 200
Cdd:COG0178  472 VGLDYLTlDRSAGTLSGGEAQRIRLAtqigsglvgvLYV--------LDEPSIGL---HQRDndrLIETLKRL-RDLGNT 539

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 536036476 201 VIAVLHD--INMAArycDYLVAL------RGGEMIAQGTPAEIMR 237
Cdd:COG0178  540 VIVVEHDedTIRAA---DYIIDIgpgageHGGEVVAQGTPEEILK 581
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 37-209 1.83e-08

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 52.38  E-value: 1.83e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476    37 GKVTGLIGHNGSGKSTLLKMLGRH-QPPSEGEILLDAqpleswsskafarkvaylpqqlppaegmtvrelvaigrypwhg 115
Cdd:smart00382   2 GEVILIVGPPGSGKTTLARALARElGPPGGGVIYIDG------------------------------------------- 38

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   116 algrfgaadrEKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVH---- 191
Cdd:smart00382  39 ----------EDILEEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLLEElrll 108

                          170
                   ....*....|....*....
gi 536036476   192 -RLSQERGLTVIAVLHDIN 209
Cdd:smart00382 109 lLLKSEKNLTVILTTNDEK 127
PRK13541 PRK13541
cytochrome c biogenesis protein CcmA; Provisional
 13-179 1.89e-08

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184128 [Multi-domain]  Cd Length: 195  Bit Score: 52.95  E-value: 1.89e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  13 ALRNISFRVPGRTLLHpLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESwSSKAFarkVAYLPQ 92
Cdd:PRK13541   3 SLHQLQFNIEQKNLFD-LSITFLPSAITYIKGANGCGKSSLLRMIAGIMQPSSGNIYYKNCNINN-IAKPY---CTYIGH 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  93 QLPPAEGMTVRELVAIGRYPWHGAlgrfgaadrEKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLD 172
Cdd:PRK13541  78 NLGLKLEMTVFENLKFWSEIYNSA---------ETLYAAIHYFKLHDLLDEKCYSLSSGMQKIVAIARLIACQSDLWLLD 148


                 ....*..
gi 536036476 173 EPTSALD 179
Cdd:PRK13541 149 EVETNLS 155
PTZ00243 PTZ00243
ABC transporter; Provisional
 14-235 3.20e-08

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 54.40  E-value: 3.20e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   14 LRNISFRVPgrtllhplsltfPAGKVtGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQQ 93
Cdd:PTZ00243 1326 LRGVSFRIA------------PREKV-GIVGRTGSGKSTLLLTFMRMVEVCGGEIRVNGREIGAYGLRELRRQFSMIPQD 1392

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   94 LPPAEGmTVRELVaigrypwhgalGRFGAADREKVEEAISLVGLKplaHRL------VDS--LSGGER----QRAWIAM- 160
Cdd:PTZ00243 1393 PVLFDG-TVRQNV-----------DPFLEASSAEVWAALELVGLR---ERVasesegIDSrvLEGGSNysvgQRQLMCMa 1457

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 536036476  161 --LVAQDSRCLLLDEPTSALDIAHQVDVLSLVhrLSQERGLTVIAVLHDINMAARYcDYLVALRGGEMIAQGTPAEI 235
Cdd:PTZ00243 1458 raLLKKGSGFILMDEATANIDPALDRQIQATV--MSAFSAYTVITIAHRLHTVAQY-DKIIVMDHGAVAEMGSPREL 1531
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 5-236 5.05e-08

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 53.49  E-value: 5.05e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476    5 TNHSDTTFALRNISFRV---PGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGR---------------------- 59
Cdd:PTZ00265 1159 KNDIKGKIEIMDVNFRYisrPNVPIYKDLTFSCDSKKTTAIVGETGSGKSTVMSLLMRfydlkndhhivfknehtndmtn 1238

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   60 ---HQPPSE-----------------------------GEILLDAQPLESWSSKAFaRKVAYLPQQLPPAEGMTVRELVA 107
Cdd:PTZ00265 1239 eqdYQGDEEqnvgmknvnefsltkeggsgedstvfknsGKILLDGVDICDYNLKDL-RNLFSIVSQEPMLFNMSIYENIK 1317

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  108 IGRYPwhgalgrfgaADREKVEEAISLVGLKPLAHRLVD-----------SLSGGERQRAWIAMLVAQDSRCLLLDEPTS 176
Cdd:PTZ00265 1318 FGKED----------ATREDVKRACKFAAIDEFIESLPNkydtnvgpygkSLSGGQKQRIAIARALLREPKILLLDEATS 1387

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 536036476  177 ALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARyCDYLVAL----RGGEMI-AQGTPAEIM 236
Cdd:PTZ00265 1388 SLDSNSEKLIEKTIVDIKDKADKTIITIAHRIASIKR-SDKIVVFnnpdRTGSFVqAHGTHEELL 1451
PRK13546 PRK13546
teichoic acids export ABC transporter ATP-binding subunit TagH;
27-236 5.96e-08

teichoic acids export ABC transporter ATP-binding subunit TagH;


Pssm-ID: 184131 [Multi-domain]  Cd Length: 264  Bit Score: 52.51  E-value: 5.96e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  27 LHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEIlldaqplESWSSKAFARKVAYLPQQLPPAEGMTVRELV 106
Cdd:PRK13546  40 LDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKV-------DRNGEVSVIAISAGLSGQLTGIENIEFKMLC 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 107 aigrypwhgaLGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDV 186
Cdd:PRK13546 113 ----------MGFKRKEIKAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLGFSINITVNPDILVIDEALSVGDQTFAQKC 182

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 536036476 187 LSLVHRLsQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIM 236
Cdd:PRK13546 183 LDKIYEF-KEQNKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYGELDDVL 231
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 14-225 9.46e-08

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 52.72  E-value: 9.46e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   14 LRNISFRVPGRT---LLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILL-DAQPLES-----WSSK--- 81
Cdd:PTZ00265  385 FKNVRFHYDTRKdveIYKDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEGDIIInDSHNLKDinlkwWRSKigv 464

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   82 ----------AFARKVAYLPQQLPPAEGMTvRELVAIGRYPWHGALGRFG-----AADREKVEEAISLVGL--------- 137
Cdd:PTZ00265  465 vsqdpllfsnSIKNNIKYSLYSLKDLEALS-NYYNEDGNDSQENKNKRNScrakcAGDLNDMSNTTDSNELiemrknyqt 543

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  138 -----------KPLAHRLVDS---------------LSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVH 191
Cdd:PTZ00265  544 ikdsevvdvskKVLIHDFVSAlpdkyetlvgsnaskLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQKTIN 623

                         250       260       270
                  ....*....|....*....|....*....|....
gi 536036476  192 RLSQERGLTVIAVLHDINmAARYCDYLVALRGGE 225
Cdd:PTZ00265  624 NLKGNENRITIIIAHRLS-TIRYANTIFVLSNRE 656
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 37-231 9.96e-08

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 52.71  E-value: 9.96e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476    37 GKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFaRKVAYLPQQLPPAEGMTVRELVAIgrypwHGA 116
Cdd:TIGR01257 1965 GECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISDVH-QNMGYCPQFDAIDDLLTGREHLYL-----YAR 2038

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   117 LGRFGAADREKVEE-AISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQ 195
Cdd:TIGR01257 2039 LRGVPAEEIEKVANwSIQSLGLSLYADRLAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNTIVSIIR 2118

                          170       180       190
                   ....*....|....*....|....*....|....*.
gi 536036476   196 ErGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGT 231
Cdd:TIGR01257 2119 E-GRAVVLTSHSMEECEALCTRLAIMVKGAFQCLGT 2153
PRK13543 PRK13543
heme ABC exporter ATP-binding protein CcmA;
13-193 1.19e-07

heme ABC exporter ATP-binding protein CcmA;


Pssm-ID: 184129 [Multi-domain]  Cd Length: 214  Bit Score: 51.00  E-value: 1.19e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  13 ALRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLeswSSKAFARKVAYLpQ 92
Cdd:PRK13543  13 AAHALAFSRNEEPVFGPLDFHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIDGKTA---TRGDRSRFMAYL-G 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  93 QLP--PAEGMTVRELvaigrypwHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLL 170
Cdd:PRK13543  89 HLPglKADLSTLENL--------HFLCGLHGRRAKQMPGSALAIVGLAGYEDTLVRQLSAGQKKRLALARLWLSPAPLWL 160

                        170       180
                 ....*....|....*....|...
gi 536036476 171 LDEPTSALDIahqvDVLSLVHRL 193
Cdd:PRK13543 161 LDEPYANLDL----EGITLVNRM 179
uvrA PRK00349
excinuclease ABC subunit UvrA;
148-235 1.42e-07

excinuclease ABC subunit UvrA;


Pssm-ID: 234734 [Multi-domain]  Cd Length: 943  Bit Score: 52.00  E-value: 1.42e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 148 LSGGERQRAWIAMLVAQDS--RCL-LLDEPTSAL---DIAHQVDVLslvHRLSqERGLTVIAVLHDINMAaRYCDYLVAL 221
Cdd:PRK00349 831 LSGGEAQRVKLAKELSKRStgKTLyILDEPTTGLhfeDIRKLLEVL---HRLV-DKGNTVVVIEHNLDVI-KTADWIIDL 905

                         90       100
                 ....*....|....*....|
gi 536036476 222 ------RGGEMIAQGTPAEI 235
Cdd:PRK00349 906 gpeggdGGGEIVATGTPEEV 925
tagH PRK13545
teichoic acids export protein ATP-binding subunit; Provisional
 12-235 3.40e-07

teichoic acids export protein ATP-binding subunit; Provisional


Pssm-ID: 184130 [Multi-domain]  Cd Length: 549  Bit Score: 50.66  E-value: 3.40e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  12 FALRNISFRVPgrtllhplsltfpAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAqpleswsSKAFARKVAYLP 91
Cdd:PRK13545  38 YALNNISFEVP-------------EGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTVDIKG-------SAALIAISSGLN 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  92 QQLPPAEGMTVRELVaigrypwhgaLGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLL 171
Cdd:PRK13545  98 GQLTGIENIELKGLM----------MGLTKEKIKEIIPEIIEFADIGKFIYQPVKTYSSGMKSRLGFAISVHINPDILVI 167

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 536036476 172 DEptsALDIAHQVDVLSLVHRLSQ--ERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEI 235
Cdd:PRK13545 168 DE---ALSVGDQTFTKKCLDKMNEfkEQGKTIFFISHSLSQVKSFCTKALWLHYGQVKEYGDIKEV 230
PRK00635 PRK00635
excinuclease ABC subunit A; Provisional
 126-240 4.21e-07

excinuclease ABC subunit A; Provisional


Pssm-ID: 234806 [Multi-domain]  Cd Length: 1809  Bit Score: 50.98  E-value: 4.21e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  126 EKVEEAISLvGLK--PLAhRLVDSLSGGERQRAWIA--MLVAQDSRCL-LLDEPTSALdiaHQVDVLSLVHRLSQ--ERG 198
Cdd:PRK00635  788 EKIHALCSL-GLDylPLG-RPLSSLSGGEIQRLKLAyeLLAPSKKPTLyVLDEPTTGL---HTHDIKALIYVLQSltHQG 862

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 536036476  199 LTVIAVLHDINMaARYCDYLVAL------RGGEMIAQGTPAEIMRGET 240
Cdd:PRK00635  863 HTVVIIEHNMHV-VKVADYVLELgpeggnLGGYLLASCSPEELIHLHT 909
ABC_UvrA cd03238
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ...
 30-230 4.38e-07

ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213205 [Multi-domain]  Cd Length: 176  Bit Score: 48.86  E-value: 4.38e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  30 LSLTFPAGKVTGLIGHNGSGKSTLLKmlgrhqppsEGEILLDAQPLESWSSKAFARKVAYLPQqlppaegmtVRELVAIG 109
Cdd:cd03238   14 LDVSIPLNVLVVVTGVSGSGKSTLVN---------EGLYASGKARLISFLPKFSRNKLIFIDQ---------LQFLIDVG 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 110 rypwhgalgrfgaadrekveeaislVGLKPLAhRLVDSLSGGERQRAWIAMLVAQDSR--CLLLDEPTSALDIAHQVDVL 187
Cdd:cd03238   76 -------------------------LGYLTLG-QKLSTLSGGELQRVKLASELFSEPPgtLFILDEPSTGLHQQDINQLL 129

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 536036476 188 SLVHRLSQErGLTVIAVLHDINMaARYCDYLVAL------RGGEMIAQG 230
Cdd:cd03238  130 EVIKGLIDL-GNTVILIEHNLDV-LSSADWIIDFgpgsgkSGGKVVFSG 176
PLN03130 PLN03130
ABC transporter C family member; Provisional
 27-239 7.23e-07

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 50.12  E-value: 7.23e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476   27 LHPLSLT-FPAGKVtGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQQlPPAEGMTVRel 105
Cdd:PLN03130 1255 LHGLSFEiSPSEKV-GIVGRTGAGKSSMLNALFRIVELERGRILIDGCDISKFGLMDLRKVLGIIPQA-PVLFSGTVR-- 1330

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  106 VAIGRYPWHGALGRFGAADREKVEEAI--SLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDiahq 183
Cdd:PLN03130 1331 FNLDPFNEHNDADLWESLERAHLKDVIrrNSLGLDAEVSEAGENFSVGQRQLLSLARALLRRSKILVLDEATAAVD---- 1406

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 536036476  184 VDVLSLVHRLSQE--RGLTVIAVLHDINMAARyCDYLVALRGGEMIAQGTPAEIMRGE 239
Cdd:PLN03130 1407 VRTDALIQKTIREefKSCTMLIIAHRLNTIID-CDRILVLDAGRVVEFDTPENLLSNE 1463
ABC_Class2 cd03227
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ...
 24-214 8.05e-07

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.


Pssm-ID: 213194 [Multi-domain]  Cd Length: 162  Bit Score: 47.74  E-value: 8.05e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  24 RTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGrhqppsegeilldaqpleswsskafarkvaylpqqlppaegmtvr 103
Cdd:cd03227    8 PSYFVPNDVTFGEGSLTIITGPNGSGKSTILDAIG--------------------------------------------- 42

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 104 eLVAIGRYPwhgALGRFGAADREKVEEAISLVglkplAHRLVDSLSGGERQRAWIAMLVA----QDSRCLLLDEPTSALD 179
Cdd:cd03227   43 -LALGGAQS---ATRRRSGVKAGCIVAAVSAE-----LIFTRLQLSGGEKELSALALILAlaslKPRPLYILDEIDRGLD 113

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 536036476 180 IAHQVDVLSLVHRLSQErGLTVIAVLHDINMAARY 214
Cdd:cd03227  114 PRDGQALAEAILEHLVK-GAQVIVITHLPELAELA 147
ABC_UvrA_I cd03270
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair ...
 135-230 2.72e-06

ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213237 [Multi-domain]  Cd Length: 226  Bit Score: 47.25  E-value: 2.72e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 135 VGLKPLA-HRLVDSLSGGERQRAWIAMLVAQ--DSRCLLLDEPTSALdiaHQVDVLSLVHRLSQER--GLTVIAVLHDIN 209
Cdd:cd03270  124 VGLGYLTlSRSAPTLSGGEAQRIRLATQIGSglTGVLYVLDEPSIGL---HPRDNDRLIETLKRLRdlGNTVLVVEHDED 200

                         90       100
                 ....*....|....*....|....*..
gi 536036476 210 MaARYCDYLVAL------RGGEMIAQG 230
Cdd:cd03270  201 T-IRAADHVIDIgpgagvHGGEIVAQG 226
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
 16-207 6.19e-06

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 46.81  E-value: 6.19e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  16 NISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQP--------------------- 74
Cdd:PRK15064   6 NITMQFGAKPLFENISVKFGGGNRYGLIGANGCGKSTFMKILGGDLEPSAGNVSLDPNErlgklrqdqfafeeftvldtv 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  75 ----LESWSSKAfARKVAYLPQQLPPAEGMTVREL-VAIGRYPWHGALGRFGaadrekveEAISLVGLKPLAHR-LVDSL 148
Cdd:PRK15064  86 imghTELWEVKQ-ERDRIYALPEMSEEDGMKVADLeVKFAEMDGYTAEARAG--------ELLLGVGIPEEQHYgLMSEV 156

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 536036476 149 SGGERQRawiaMLVAQ----DSRCLLLDEPTSALDIaHQV----DVLSlvhrlsqERGLTVIAVLHD 207
Cdd:PRK15064 157 APGWKLR----VLLAQalfsNPDILLLDEPTNNLDI-NTIrwleDVLN-------ERNSTMIIISHD 211
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
 24-180 1.18e-05

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 46.32  E-value: 1.18e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  24 RTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLgrhqppsEGEILLDAQPL---ESWSskafarkVAYLPQQlPPAEGM 100
Cdd:PRK10636  14 RVLLDNATATINPGQKVGLVGKNGCGKSTLLALL-------KNEISADGGSYtfpGNWQ-------LAWVNQE-TPALPQ 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 101 TVRELVAIGRYPWHGALGRFGAADREKVEEAISLVGLK--------------PLAHRL----------VDSLSGGERQRA 156
Cdd:PRK10636  79 PALEYVIDGDREYRQLEAQLHDANERNDGHAIATIHGKldaidawtirsraaSLLHGLgfsneqlerpVSDFSGGWRMRL 158

                        170       180
                 ....*....|....*....|....
gi 536036476 157 WIAMLVAQDSRCLLLDEPTSALDI 180
Cdd:PRK10636 159 NLAQALICRSDLLLLDEPTNHLDL 182
PLN03073 PLN03073
ABC transporter F family; Provisional
 14-184 2.50e-05

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 45.24  E-value: 2.50e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  14 LRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQP---PSEGEILLDAQPLESWSSKAFA------ 84
Cdd:PLN03073 180 MENFSISVGGRDLIVDASVTLAFGRHYGLVGRNGTGKTTFLRYMAMHAIdgiPKNCQILHVEQEVVGDDTTALQcvlntd 259

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  85 -------RKVAYLPQQLPPAEGMTVRelvAIGRYPWHGALGRFGAADR----EKVEEAIS-----------LVGLK---P 139
Cdd:PLN03073 260 iertqllEEEAQLVAQQRELEFETET---GKGKGANKDGVDKDAVSQRleeiYKRLELIDaytaearaasiLAGLSftpE 336

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 536036476 140 LAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIaHQV 184
Cdd:PLN03073 337 MQVKATKTFSGGWRMRIALARALFIEPDLLLLDEPTNHLDL-HAV 380
ABC_Rad50 cd03240
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ...
 39-207 3.93e-05

ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.


Pssm-ID: 213207 [Multi-domain]  Cd Length: 204  Bit Score: 43.36  E-value: 3.93e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  39 VTGLIGHNGSGKSTL---LKM-LGRHQPPSEGEILLDAQPLESWSSKAfarkVAYLPQQLPPAEGMTVRELVAIGRYpwh 114
Cdd:cd03240   24 LTLIVGQNGAGKTTIieaLKYaLTGELPPNSKGGAHDPKLIREGEVRA----QVKLAFENANGKKYTITRSLAILEN--- 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 115 galgrfgaADREKVEEAislvgLKPLAhRLVDSLSGGERQ------RAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLS 188
Cdd:cd03240   97 --------VIFCHQGES-----NWPLL-DMRGRCSGGEKVlasliiRLALAETFGSNCGILALDEPTTNLDEENIEESLA 162

                        170       180
                 ....*....|....*....|
gi 536036476 189 -LVHRLSQERGLTVIAVLHD 207
Cdd:cd03240  163 eIIEERKSQKNFQLIVITHD 182
PRK00635 PRK00635
excinuclease ABC subunit A; Provisional
 143-236 1.26e-04

excinuclease ABC subunit A; Provisional


Pssm-ID: 234806 [Multi-domain]  Cd Length: 1809  Bit Score: 43.28  E-value: 1.26e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476  143 RLVDSLSGGERQRAWIAM-LVAQDSRCL-LLDEPTSALdiaHQVDVLSLVHRLSQER--GLTVIAVLHDINMAArYCDYL 218
Cdd:PRK00635  472 RALATLSGGEQERTALAKhLGAELIGITyILDEPSIGL---HPQDTHKLINVIKKLRdqGNTVLLVEHDEQMIS-LADRI 547

                          90       100
                  ....*....|....*....|....
gi 536036476  219 V------ALRGGEMIAQGTPAEIM 236
Cdd:PRK00635  548 IdigpgaGIFGGEVLFNGSPREFL 571
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
125-243 6.06e-04

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 40.49  E-value: 6.06e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 536036476 125 REKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQErGLTVIAV 204
Cdd:NF000106 122 RARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMVRD-GATVLLT 200

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 536036476 205 LHDINMAARYCDYLVALRGGEMIAQGTPAEI---MRGETLEM 243
Cdd:NF000106 201 TQYMEEAEQLAHELTVIDRGRVIADGKVDELktkVGGRTLQI 242
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 139-203 3.77e-03

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 38.17  E-value: 3.77e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 536036476 139 PLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQE-RGLTVIA 203
Cdd:PRK10982 383 PGHRTQIGSLSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIAELAKKdKGIIIIS 448
COG4637 COG4637
Predicted ATPase [General function prediction only];
10-54 5.45e-03

Predicted ATPase [General function prediction only];


Pssm-ID: 443675 [Multi-domain]  Cd Length: 371  Bit Score: 37.60  E-value: 5.45e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 536036476  10 TTFALRNI-SFRvpgrtllhplSLTFPAGKVTGLIGHNGSGKSTLL 54
Cdd:COG4637    3 TRIRIKNFkSLR----------DLELPLGPLTVLIGANGSGKSNLL 38
COG3910 COG3910
Predicted ATPase [General function prediction only];
27-54 9.87e-03

Predicted ATPase [General function prediction only];


Pssm-ID: 443116 [Multi-domain]  Cd Length: 239  Bit Score: 36.67  E-value: 9.87e-03
                         10        20
                 ....*....|....*....|....*...
gi 536036476  27 LHPLSLTFPagkVTGLIGHNGSGKSTLL 54
Cdd:COG3910   30 LEGLEFHPP---VTFFVGENGSGKSTLL 54
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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