NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|550181995|gb|ERO72844|]
View 

hypothetical protein L445_05437 [Klebsiella pneumoniae BIDMC 16]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
CaiF_GrlA super family cl06280
CaiF/GrlA transcriptional regulator; This is a family of transcriptional regulators. CaiF is ...
 10-91 1.15e-06

CaiF/GrlA transcriptional regulator; This is a family of transcriptional regulators. CaiF is involved in carnitine metabolism. GrlA is encoded within the LEE type III secretion system in the enteropathogenic E. coli O157:H. GrlR interacts with GrlA at its Helix-Turn-Helix (HTH) motif, preventing GrlA from binding to its target promoter DNA.


The actual alignment was detected with superfamily member pfam07180:

Pssm-ID: 369250  Cd Length: 134  Bit Score: 45.00  E-value: 1.15e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550181995   10 VIPECVADLKGYPLYIIVAYWGLRNNKTLTTTDVSRNFLITQQQSYDVLTYIYQEAQKQITATK-RTLFNEHKRRISAF- 87
Cdd:pfam07180   9 VIPDSVKNYDGEPLYILVSLWCKLQEKWISRNDIAEAFGINLRRASFIITYISRRKEKISFRVRyVSYGNLHYKRLEIFi 88


                  ....*
gi 550181995   88 -RILD 91
Cdd:pfam07180  89 yDVNL 93
 
Name Accession Description Interval E-value
CaiF_GrlA pfam07180
CaiF/GrlA transcriptional regulator; This is a family of transcriptional regulators. CaiF is ...
 10-91 1.15e-06

CaiF/GrlA transcriptional regulator; This is a family of transcriptional regulators. CaiF is involved in carnitine metabolism. GrlA is encoded within the LEE type III secretion system in the enteropathogenic E. coli O157:H. GrlR interacts with GrlA at its Helix-Turn-Helix (HTH) motif, preventing GrlA from binding to its target promoter DNA.


Pssm-ID: 369250  Cd Length: 134  Bit Score: 45.00  E-value: 1.15e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550181995   10 VIPECVADLKGYPLYIIVAYWGLRNNKTLTTTDVSRNFLITQQQSYDVLTYIYQEAQKQITATK-RTLFNEHKRRISAF- 87
Cdd:pfam07180   9 VIPDSVKNYDGEPLYILVSLWCKLQEKWISRNDIAEAFGINLRRASFIITYISRRKEKISFRVRyVSYGNLHYKRLEIFi 88


                  ....*
gi 550181995   88 -RILD 91
Cdd:pfam07180  89 yDVNL 93
 
Name Accession Description Interval E-value
CaiF_GrlA pfam07180
CaiF/GrlA transcriptional regulator; This is a family of transcriptional regulators. CaiF is ...
 10-91 1.15e-06

CaiF/GrlA transcriptional regulator; This is a family of transcriptional regulators. CaiF is involved in carnitine metabolism. GrlA is encoded within the LEE type III secretion system in the enteropathogenic E. coli O157:H. GrlR interacts with GrlA at its Helix-Turn-Helix (HTH) motif, preventing GrlA from binding to its target promoter DNA.


Pssm-ID: 369250  Cd Length: 134  Bit Score: 45.00  E-value: 1.15e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550181995   10 VIPECVADLKGYPLYIIVAYWGLRNNKTLTTTDVSRNFLITQQQSYDVLTYIYQEAQKQITATK-RTLFNEHKRRISAF- 87
Cdd:pfam07180   9 VIPDSVKNYDGEPLYILVSLWCKLQEKWISRNDIAEAFGINLRRASFIITYISRRKEKISFRVRyVSYGNLHYKRLEIFi 88


                  ....*
gi 550181995   88 -RILD 91
Cdd:pfam07180  89 yDVNL 93
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH