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Conserved domains on  [gi|550691694|gb|ERS15548|]
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peptidoglycan transglycosylase [Alcanivorax sp. PN-3]

Protein Classification

biosynthetic peptidoglycan transglycosylase( domain architecture ID 1001727)

biosynthetic peptidoglycan transglycosylase is involved in the final stages of peptidoglycan synthesis

CATH:  1.10.3810.10
Gene Ontology:  GO:0071555|GO:0008955|GO:0009252|GO:0008360
PubMed:  8830253
SCOP:  4002510

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK13481 super family cl29529
glycosyltransferase; Provisional
 7-221 3.55e-78

glycosyltransferase; Provisional


The actual alignment was detected with superfamily member TIGR02070:

Pssm-ID: 475222 [Multi-domain]  Cd Length: 224  Bit Score: 234.28  E-value: 3.55e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550691694    7 SLLGLAVIVVLGTQLWFLGQVLYLRAYNPQNTAFME----RSRQHGTV----QYLWRDYDQIATDLKRAVLVSEDARFVE 78
Cdd:TIGR02070   2 YVIGCLVAGVLLFNLAVFAALASWRFVPPPSTAFMVaeklALWGQGDPtcgiQHRWRPYDQISPNLKRAVIASEDAKFVE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550691694   79 HIGFDWRGIRHAIERNRKAGRPVAGGSTITQQLAKNLFLNSDRSYWRKGQEALIALMLEATMSKQRILELYLNTAQWGNR 158
Cdd:TIGR02070  82 HHGFDWEAIQDALEKNEKSGKVVRGGSTISQQLAKNLFLWSGRSYLRKGLEAWATWMLETWWSKQRILEVYLNSVEWGNG 161

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 550691694  159 IFGAEAAARHYFGISAASLGPAQAAQLAAMLPRPSYYDVRGVTDYVHQRTQWIQNQLPLVALP 221
Cdd:TIGR02070 162 VFGAEAAARYYFKRSASNLTRGQAARLAAVLPNPKYYDENRPGPYVRRKATWILKQMGYLGLP 224
 
Name Accession Description Interval E-value
mono_pep_trsgly TIGR02070
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the ...
 7-221 3.55e-78

monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the transglycosylases involved in the late stages of peptidoglycan biosynthesis. Members tend to be small, about 240 amino acids in length, and consist almost entirely of a domain described by pfam00912 for transglycosylases. Species with this protein will have several other transglycosylases as well. All species with this protein are Proteobacteria that produce murein (peptidoglycan). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]


Pssm-ID: 273951 [Multi-domain]  Cd Length: 224  Bit Score: 234.28  E-value: 3.55e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550691694    7 SLLGLAVIVVLGTQLWFLGQVLYLRAYNPQNTAFME----RSRQHGTV----QYLWRDYDQIATDLKRAVLVSEDARFVE 78
Cdd:TIGR02070   2 YVIGCLVAGVLLFNLAVFAALASWRFVPPPSTAFMVaeklALWGQGDPtcgiQHRWRPYDQISPNLKRAVIASEDAKFVE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550691694   79 HIGFDWRGIRHAIERNRKAGRPVAGGSTITQQLAKNLFLNSDRSYWRKGQEALIALMLEATMSKQRILELYLNTAQWGNR 158
Cdd:TIGR02070  82 HHGFDWEAIQDALEKNEKSGKVVRGGSTISQQLAKNLFLWSGRSYLRKGLEAWATWMLETWWSKQRILEVYLNSVEWGNG 161

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 550691694  159 IFGAEAAARHYFGISAASLGPAQAAQLAAMLPRPSYYDVRGVTDYVHQRTQWIQNQLPLVALP 221
Cdd:TIGR02070 162 VFGAEAAARYYFKRSASNLTRGQAARLAAVLPNPKYYDENRPGPYVRRKATWILKQMGYLGLP 224
MrcB COG0744
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ...
 1-177 6.72e-64

Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440507 [Multi-domain]  Cd Length: 630  Bit Score: 209.01  E-value: 6.72e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550691694   1 MKRFFLSL-LGLAVIVVLGTQLWFLGQVL------YLRAYNPQNTAFMERSR-----QHGTVQYLWRDYDQIATDLKRAV 68
Cdd:COG0744   11 LRRLLGLLlLLLAVLVLAALAGLVALYVAdlpdpeELEDLALPQTSTIYDRDgtliaTLGDENREWVPLDQIPPHLKDAV 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550691694  69 LVSEDARFVEHIGFDWRGIRHAIERNRKAGRPVAGGSTITQQLAKNLFLNSDRSYWRKGQEALIALMLEATMSKQRILEL 148
Cdd:COG0744   91 VAIEDRRFYEHGGVDPKGIARALVANLTAGGVVQGGSTITQQLVKNLFLSNERTLSRKLKEALLALKLERKYSKDEILEL 170

                        170       180
                 ....*....|....*....|....*....
gi 550691694 149 YLNTAQWGNRIFGAEAAARHYFGISAASL 177
Cdd:COG0744  171 YLNTVYFGRGAYGIEAAAQYYFGKSASDL 199
Transgly pfam00912
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ...
 54-215 4.96e-61

Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.


Pssm-ID: 459993 [Multi-domain]  Cd Length: 177  Bit Score: 188.88  E-value: 4.96e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550691694   54 WRDYDQIATDLKRAVLVSEDARFVEHIGFDWRGIRHAIERNRKAGRPVAGGSTITQQLAKNLFLNSDRSYWRKGQEALIA 133
Cdd:pfam00912  15 YVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRIVQGGSTITQQLAKNLFLTPERTLTRKLKEAVLA 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550691694  134 LMLEATMSKQRILELYLNTAQWGNRIFGAEAAARHYFGISAASLGPAQAAQLAAMLPRPSYYDVRGVTDYVHQRTQWIQN 213
Cdd:pfam00912  95 LKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNPLRNPERAKRRRNLVLD 174


                  ..
gi 550691694  214 QL 215
Cdd:pfam00912 175 RM 176
mrcB PRK09506
bifunctional glycosyl transferase/transpeptidase; Reviewed
 69-171 1.21e-27

bifunctional glycosyl transferase/transpeptidase; Reviewed


Pssm-ID: 236544 [Multi-domain]  Cd Length: 830  Bit Score: 110.24  E-value: 1.21e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550691694  69 LVSEDARFVEHIGFDWRGIRHAIERNRKAGRPVAGGSTITQQLAKNLFLNSDRSYWRKGQEALIALMLEATMSKQRILEL 148
Cdd:PRK09506 228 LATEDRHFYEHDGISLYSIGRAVLANLTAGRTVQGGSTLTQQLVKNLFLSNERSLWRKANEAYMALIMDARYSKDRILEL 307

                         90       100
                 ....*....|....*....|....*..
gi 550691694 149 YLNTAQWG----NRIFGAEAAARHYFG 171
Cdd:PRK09506 308 YLNEVYLGqsgdDQIRGFPLASLYYFG 334
 
Name Accession Description Interval E-value
mono_pep_trsgly TIGR02070
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the ...
 7-221 3.55e-78

monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the transglycosylases involved in the late stages of peptidoglycan biosynthesis. Members tend to be small, about 240 amino acids in length, and consist almost entirely of a domain described by pfam00912 for transglycosylases. Species with this protein will have several other transglycosylases as well. All species with this protein are Proteobacteria that produce murein (peptidoglycan). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]


Pssm-ID: 273951 [Multi-domain]  Cd Length: 224  Bit Score: 234.28  E-value: 3.55e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550691694    7 SLLGLAVIVVLGTQLWFLGQVLYLRAYNPQNTAFME----RSRQHGTV----QYLWRDYDQIATDLKRAVLVSEDARFVE 78
Cdd:TIGR02070   2 YVIGCLVAGVLLFNLAVFAALASWRFVPPPSTAFMVaeklALWGQGDPtcgiQHRWRPYDQISPNLKRAVIASEDAKFVE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550691694   79 HIGFDWRGIRHAIERNRKAGRPVAGGSTITQQLAKNLFLNSDRSYWRKGQEALIALMLEATMSKQRILELYLNTAQWGNR 158
Cdd:TIGR02070  82 HHGFDWEAIQDALEKNEKSGKVVRGGSTISQQLAKNLFLWSGRSYLRKGLEAWATWMLETWWSKQRILEVYLNSVEWGNG 161

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 550691694  159 IFGAEAAARHYFGISAASLGPAQAAQLAAMLPRPSYYDVRGVTDYVHQRTQWIQNQLPLVALP 221
Cdd:TIGR02070 162 VFGAEAAARYYFKRSASNLTRGQAARLAAVLPNPKYYDENRPGPYVRRKATWILKQMGYLGLP 224
MrcB COG0744
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ...
 1-177 6.72e-64

Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440507 [Multi-domain]  Cd Length: 630  Bit Score: 209.01  E-value: 6.72e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550691694   1 MKRFFLSL-LGLAVIVVLGTQLWFLGQVL------YLRAYNPQNTAFMERSR-----QHGTVQYLWRDYDQIATDLKRAV 68
Cdd:COG0744   11 LRRLLGLLlLLLAVLVLAALAGLVALYVAdlpdpeELEDLALPQTSTIYDRDgtliaTLGDENREWVPLDQIPPHLKDAV 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550691694  69 LVSEDARFVEHIGFDWRGIRHAIERNRKAGRPVAGGSTITQQLAKNLFLNSDRSYWRKGQEALIALMLEATMSKQRILEL 148
Cdd:COG0744   91 VAIEDRRFYEHGGVDPKGIARALVANLTAGGVVQGGSTITQQLVKNLFLSNERTLSRKLKEALLALKLERKYSKDEILEL 170

                        170       180
                 ....*....|....*....|....*....
gi 550691694 149 YLNTAQWGNRIFGAEAAARHYFGISAASL 177
Cdd:COG0744  171 YLNTVYFGRGAYGIEAAAQYYFGKSASDL 199
Transgly pfam00912
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ...
 54-215 4.96e-61

Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.


Pssm-ID: 459993 [Multi-domain]  Cd Length: 177  Bit Score: 188.88  E-value: 4.96e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550691694   54 WRDYDQIATDLKRAVLVSEDARFVEHIGFDWRGIRHAIERNRKAGRPVAGGSTITQQLAKNLFLNSDRSYWRKGQEALIA 133
Cdd:pfam00912  15 YVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRIVQGGSTITQQLAKNLFLTPERTLTRKLKEAVLA 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550691694  134 LMLEATMSKQRILELYLNTAQWGNRIFGAEAAARHYFGISAASLGPAQAAQLAAMLPRPSYYDVRGVTDYVHQRTQWIQN 213
Cdd:pfam00912  95 LKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNPLRNPERAKRRRNLVLD 174


                  ..
gi 550691694  214 QL 215
Cdd:pfam00912 175 RM 176
PBP_1a_fam TIGR02074
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ...
 56-177 6.37e-48

penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]


Pssm-ID: 273955 [Multi-domain]  Cd Length: 531  Bit Score: 164.74  E-value: 6.37e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550691694   56 DYDQIATDLKRAVLVSEDARFVEHIGFDWRGIRHAIERNRKAGRPVAGGSTITQQLAKNLFLNSDRSYWRKGQEALIALM 135
Cdd:TIGR02074   6 PIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVANITSGRVLEGGSTITQQLAKNLYLTNERTITRKIQEALLALK 85

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 550691694  136 LEATMSKQRILELYLNTAQWGNRIFGAEAAARHYFGISAASL 177
Cdd:TIGR02074  86 LEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDL 127
MrcA COG5009
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
1-177 1.01e-44

Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 444033 [Multi-domain]  Cd Length: 785  Bit Score: 158.78  E-value: 1.01e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550691694   1 MKRFFLSLLGLAVIVVLGtqlwFLGQVLY----------LRAYNPQNTafmerSR---QHGTV--QY-----LWRDYDQI 60
Cdd:COG5009    4 LKILLILLLLLLLLGALA----VAGLYLYlspdlpdvetLKDYQPPTP-----SRvysADGKLiaEFgeerrIPVPIEEI 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550691694  61 ATDLKRAVLVSEDARFVEHIGFDWRGIRHAIERNRKAGRPVAGGSTITQQLAKNLFLNSDRSYWRKGQEALIALMLEATM 140
Cdd:COG5009   75 PPLLINAFLAAEDKRFYEHPGVDPIGIARAAVVNLRTGRRVQGGSTITQQVAKNFLLSPERTLTRKIKEAILALRIEQEL 154

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 550691694 141 SKQRILELYLNTAQWGNRIFGAEAAARHYFGISAASL 177
Cdd:COG5009  155 SKDEILELYLNKIYLGHRAYGVAAAAQTYFGKSLDEL 191
PbpC COG4953
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope ...
 1-177 1.53e-33

Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443980 [Multi-domain]  Cd Length: 773  Bit Score: 126.87  E-value: 1.53e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550691694   1 MKRFFL----SLLGLAVIVVLGTQLWFLGQV--LYLRAYNPQNTAFMERsrqHGTV---------QY-LWRDYDQIATDL 64
Cdd:COG4953    1 MKRARLrrrrLLALLLALLLLALALWALDRLfpLPLLFAVPYSTVVLDR---DGTLlraflaadgQWrLPVPLDEVSPRY 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550691694  65 KRAVLVSEDARFVEHIGFDWRGIRHAIERNRKAGRPVAGGSTITQQLAKnLFLNSDRSYWRKGQEALIALMLEATMSKQR 144
Cdd:COG4953   78 LQALLAYEDRRFYYHPGVNPLALLRAAWQNLRSGRIVSGGSTLTMQVAR-LLEPRPRTLSGKLRQILRALQLERRYSKDE 156

                        170       180       190
                 ....*....|....*....|....*....|...
gi 550691694 145 ILELYLNTAQWGNRIFGAEAAARHYFGISAASL 177
Cdd:COG4953  157 ILELYLNLAPYGGNIEGVEAASLAYFGKPPSRL 189
PBP_1b TIGR02071
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) ...
 58-198 1.14e-31

penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of a particular bifunctional transglycosylase/transpeptidase in E. coli and other Proteobacteria, designated penicillin-binding protein 1B. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]


Pssm-ID: 273952 [Multi-domain]  Cd Length: 730  Bit Score: 121.75  E-value: 1.14e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550691694   58 DQIATDLKRAVLVSEDARFVEHIGFDWRGIRHAIERNRKAGRPVAGGSTITQQLAKNLFLNSDRSYWRKGQEALIALMLE 137
Cdd:TIGR02071 153 DQFPELLVDTLLATEDRDFYEHDGISLYSIGRAVWVNLTAGRTVQGGSTLTQQLVKNLFLSNERSLWRKANEAYMALILD 232

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 550691694  138 ATMSKQRILELYLNTAQWGNR----IFGAEAAARHYFGISAASLGPAQAAQLAAMLPRPSYYDVR 198
Cdd:TIGR02071 233 ARYSKDRILELYLNEVYLGQSgddaIHGFPLASQYYFGRPLGELSLDQVALLVGMVKGPSYYNPW 297
mrcB PRK09506
bifunctional glycosyl transferase/transpeptidase; Reviewed
 69-171 1.21e-27

bifunctional glycosyl transferase/transpeptidase; Reviewed


Pssm-ID: 236544 [Multi-domain]  Cd Length: 830  Bit Score: 110.24  E-value: 1.21e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550691694  69 LVSEDARFVEHIGFDWRGIRHAIERNRKAGRPVAGGSTITQQLAKNLFLNSDRSYWRKGQEALIALMLEATMSKQRILEL 148
Cdd:PRK09506 228 LATEDRHFYEHDGISLYSIGRAVLANLTAGRTVQGGSTLTQQLVKNLFLSNERSLWRKANEAYMALIMDARYSKDRILEL 307

                         90       100
                 ....*....|....*....|....*..
gi 550691694 149 YLNTAQWG----NRIFGAEAAARHYFG 171
Cdd:PRK09506 308 YLNEVYLGqsgdDQIRGFPLASLYYFG 334
PRK13481 PRK13481
glycosyltransferase; Provisional
 64-173 2.18e-27

glycosyltransferase; Provisional


Pssm-ID: 184078 [Multi-domain]  Cd Length: 232  Bit Score: 104.11  E-value: 2.18e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550691694  64 LKRAVLVSEDARFVEHIGFDWRGIRHAIERNRKaGRPVAGGSTITQQLAKNLFLNSDRSYWRKGQEALIALMLEATMSKQ 143
Cdd:PRK13481  57 VKGAFISMEDERFYKHHGFDLKGTTRALFSTIS-DRDVQGGSTITQQVVKNYFYDNERSFTRKVKELFVAHRVEKQYSKN 135

                         90       100       110
                 ....*....|....*....|....*....|
gi 550691694 144 RILELYLNTAQWGNRIFGAEAAARHYFGIS 173
Cdd:PRK13481 136 EILSFYLNNIYFGDNQYTLEGAANHYFGTT 165
PBP_1c TIGR02073
penicillin-binding protein 1C; This subfamily of the penicillin binding proteins includes the ...
 53-177 9.91e-27

penicillin-binding protein 1C; This subfamily of the penicillin binding proteins includes the member from E. coli designated penicillin-binding protein 1C. Members have both transglycosylase and transpeptidase domains and are involved in forming cross-links in the late stages of peptidoglycan biosynthesis. All members of this subfamily are presumed to have the same basic function. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]


Pssm-ID: 273954 [Multi-domain]  Cd Length: 727  Bit Score: 107.51  E-value: 9.91e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550691694   53 LWRDYDQIATDLKRAVLVSEDARFVEHIGFDWRGIRHAIERNRKAGRPVAGGSTITQQLAKnLFLNSD-RSYWRKGQEAL 131
Cdd:TIGR02073  34 LPVPLEDISPKFLQALLLYEDKRFYWHPGVNPLALLRAAWQNLTNGRRVSGGSTLTMQLAR-LLDPELsRTLTGKLRQMW 112

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 550691694  132 IALMLEATMSKQRILELYLNTAQWGNRIFGAEAAARHYFGISAASL 177
Cdd:TIGR02073 113 RAIQLEARYSKREILEAYLNLAPYGGNLEGLRAASLIYFGKEPSSL 158
mrcA PRK11636
penicillin-binding protein 1a; Provisional
 58-177 9.93e-27

penicillin-binding protein 1a; Provisional


Pssm-ID: 183248 [Multi-domain]  Cd Length: 850  Bit Score: 107.52  E-value: 9.93e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550691694  58 DQIATDLKRAVLVSEDARFVEHIGFDWRGIRHAIERNRKAGRPVAGGSTITQQLAKNLFLNSDRSYWRKGQEALIALMLE 137
Cdd:PRK11636  72 DQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEAFLAIRIE 151

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 550691694 138 ATMSKQRILELYLNTAQWGNRIFGAEAAARHYFGISAASL 177
Cdd:PRK11636 152 QLLTKDEILELYLNKIYLGYRAYGVGAAAQVYFGKTVDQL 191
PRK14850 PRK14850
penicillin-binding protein 1b; Provisional
 64-171 8.25e-22

penicillin-binding protein 1b; Provisional


Pssm-ID: 237835 [Multi-domain]  Cd Length: 764  Bit Score: 92.99  E-value: 8.25e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550691694  64 LKRAVLVSEDARFVEHIGFDWRGIRHAIERNRKAGRPVAGGSTITQQLAKNLFLNSDRSYWRKGQEALIALMLEATMSKQ 143
Cdd:PRK14850 169 LIKTLLAIEDKYFYEHDGIHLSSIGRAFLVNLMSGHTIQGGSTLTQQLVKNLFLTNTRSLWRKINEIYMALILDRFYSKD 248

                         90       100       110
                 ....*....|....*....|....*....|..
gi 550691694 144 RILELYLNTAQWG----NRIFGAEAAARHYFG 171
Cdd:PRK14850 249 RILELYLNEVYLGqdgnEQIRGFPLASIYYFG 280
PRK11240 PRK11240
penicillin-binding protein 1C; Provisional
 67-179 6.21e-11

penicillin-binding protein 1C; Provisional


Pssm-ID: 183049 [Multi-domain]  Cd Length: 772  Bit Score: 61.25  E-value: 6.21e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550691694  67 AVLVSEDARFVEHIGFDWRGIRHAIERNRKAGRPVAGGSTITQQLAKNL------FLNSDRSYWRkgqealiALMLEATM 140
Cdd:PRK11240  77 ALINYEDRWFWKHPGVNPFSVARAAWQDLTSGRVISGGSTLTMQVARLLdphprtFGGKIRQLWR-------ALQLEWHL 149

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 550691694 141 SKQRILELYLNTAQWGNRIFGAEAAARHYFGISAASLGP 179
Cdd:PRK11240 150 SKREILTLYLNRAPFGGTLQGIGAASWAYLGKSPANLSY 188
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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