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Conserved domains on  [gi|578222444|gb|EUL82616|]
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sn-glycerol-3-phosphate transport system permease ugpA [Enterobacter kobei]

Protein Classification

sn-glycerol-3-phosphate ABC transporter permease UgpA( domain architecture ID 10793417)

sn-glycerol-3-phosphate ABC transporter permease UgpA is part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate, and is probably responsible for the translocation of the substrate across the membrane

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK10561 PRK10561
sn-glycerol-3-phosphate ABC transporter permease UgpA;
16-295 1.34e-170

sn-glycerol-3-phosphate ABC transporter permease UgpA;


:

Pssm-ID: 182550 [Multi-domain]  Cd Length: 280  Bit Score: 473.54  E-value: 1.34e-170
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444  16 LLVAPQLVITVIFFIWPAGEALWYSVQSVDPFGLSSQFVGLDNFTALFHDSYYLDSFWTTMKFSALVTVSGLVASLFFAA 95
Cdd:PRK10561   1 LLVAPQLIITVIFFIWPAGEALWYSLQSVDPFGFSSQFVGLDNFVALFHDSYYLDSFWTTIKFSTLVTVSGLLVSLFFAA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444  96 LVDYVVRGSRLYQTLMLLPYAVAPAVAAVLWIFLFNPGRGLITHFLAELGYDWNHAQNSGQAMFLVVFASVWKQISYNFL 175
Cdd:PRK10561  81 LVDYVVRGSRFYQTLMLLPYAVAPAVAAVLWIFLFNPGRGLITHFLAEFGYDWNHAQNSGQAMFLVVFASVWKQISYNFL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444 176 FFFAALQSIPRSLVEAAAIDGAGPVRRFFRLSLPLIAPVSFFLLVVNLVYAFFDTFPVIDAATAGGPVQATTTLIYKIYR 255
Cdd:PRK10561 161 FFFAALQSIPRSLVEAAAIDGAGPIRRFFKLALPLIAPVSFFLLVVNLVYAFFDTFPVIDAATSGGPVQATTTLIYKIYR 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 578222444 256 EGFAGLDLSASAAQSVVLMFLVIILTVVQFRYVESKVRYQ 295
Cdd:PRK10561 241 EGFTGLDLSSSAAQSVVLMFLVIVLTVVQFRYVESKVRYQ 280
 
Name Accession Description Interval E-value
PRK10561 PRK10561
sn-glycerol-3-phosphate ABC transporter permease UgpA;
16-295 1.34e-170

sn-glycerol-3-phosphate ABC transporter permease UgpA;


Pssm-ID: 182550 [Multi-domain]  Cd Length: 280  Bit Score: 473.54  E-value: 1.34e-170
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444  16 LLVAPQLVITVIFFIWPAGEALWYSVQSVDPFGLSSQFVGLDNFTALFHDSYYLDSFWTTMKFSALVTVSGLVASLFFAA 95
Cdd:PRK10561   1 LLVAPQLIITVIFFIWPAGEALWYSLQSVDPFGFSSQFVGLDNFVALFHDSYYLDSFWTTIKFSTLVTVSGLLVSLFFAA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444  96 LVDYVVRGSRLYQTLMLLPYAVAPAVAAVLWIFLFNPGRGLITHFLAELGYDWNHAQNSGQAMFLVVFASVWKQISYNFL 175
Cdd:PRK10561  81 LVDYVVRGSRFYQTLMLLPYAVAPAVAAVLWIFLFNPGRGLITHFLAEFGYDWNHAQNSGQAMFLVVFASVWKQISYNFL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444 176 FFFAALQSIPRSLVEAAAIDGAGPVRRFFRLSLPLIAPVSFFLLVVNLVYAFFDTFPVIDAATAGGPVQATTTLIYKIYR 255
Cdd:PRK10561 161 FFFAALQSIPRSLVEAAAIDGAGPIRRFFKLALPLIAPVSFFLLVVNLVYAFFDTFPVIDAATSGGPVQATTTLIYKIYR 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 578222444 256 EGFAGLDLSASAAQSVVLMFLVIILTVVQFRYVESKVRYQ 295
Cdd:PRK10561 241 EGFTGLDLSSSAAQSVVLMFLVIVLTVVQFRYVESKVRYQ 280
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
2-292 1.69e-82

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 250.44  E-value: 1.69e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444   2 SSSRPVFRSRWLPYLLVAPQLVITVIFFIWPAGEALWYSVQSVDPFGLSSQFVGLDNFTALFHDSYYLDSFWTTMKFSAL 81
Cdd:COG1175    8 AARRRRRRRRLAAYLFLLPALLLLLVFVLYPLLYTLYLSFTDWNLLGPPPEFVGLDNYARLFTDPRFWNALGNTLLFTVV 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444  82 VTVSGLVASLFFAALVDYVVRGSRLYQTLMLLPYAVAPAVAAVLWIFLFNPGRGLITHFLAELGYD-WNHAQNSGQAMFL 160
Cdd:COG1175   88 SVPLQLVLGLLLALLLNRKLRGRGFFRTLFFLPWVISPVVVALIWKWLFNPDYGLLNALLGALGLEpINWLGDPSLALPA 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444 161 VVFASVWKQISYNFLFFFAALQSIPRSLVEAAAIDGAGPVRRFFRLSLPLIAPVSFFLLVVNLVYAfFDTFPVIDAATAG 240
Cdd:COG1175  168 VIIVTVWKGTGFNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGA-LQVFDLVYVLTGG 246

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|..
gi 578222444 241 GPVQATTTLIYKIYREGFAGLDLSASAAQSVVLMFLVIILTVVQFRYVESKV 292
Cdd:COG1175  247 GPGNSTTTLVLYIYQTAFQQFDFGYASAIAVVLFLIILVLTLLQLRLLRRRE 298
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 133-294 2.71e-10

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 58.46  E-value: 2.71e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444  133 GRGLITHFLAELGYDWNHAQNSGQAMFLVVFASVWKQISYNFLFFFAALQSIPRSLVEAAAIDGAGPVRRFFRLSLPLIA 212
Cdd:pfam00528  27 LQALPSFVLAILLVVIAILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNAL 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444  213 PVSFFLLVVNLVYAFFDTFpVIDAATAGGPVQATTTLIYKIYREGFAgldlSASAAQSVVLMFLVIILTVVQFRYVESKV 292
Cdd:pfam00528 107 PPILTGLALAFGGALGGAV-LLEFLGSWPGLGLLLIEAILGYDYPEI----QGPVLAAALILLLLNLLVDILQRLLDPRV 181


                  ..
gi 578222444  293 RY 294
Cdd:pfam00528 182 RK 183
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 72-278 2.02e-08

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 53.05  E-value: 2.02e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444  72 FWTTMKFSALVTVSGLVASLFFA-ALVDYVVRGSRLYQTLMLLPYAVAPAVAAVLWIFLFnpgrglithflaelGYDWNH 150
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGiILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLF--------------GVLLGW 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444 151 AQNSGQAMFLVVFASVWkQISYNFLFFFAALQSIPRSLVEAAAIDGAGPVRRFFRLSLPLIAPVSFFLLVVNLVYAFFDT 230
Cdd:cd06261   67 GILPGLGLPALILALLL-IAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEF 145

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 578222444 231 FPVidaATAGGPVQATTTLIYKIYREGFAGLDLSASAAQSVVLMFLVI 278
Cdd:cd06261  146 ALV---SFLGGGEAPGPGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 12-209 4.98e-08

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 53.92  E-value: 4.98e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444   12 WLPYLLVAPQLVITVIFFIWPAGEALWYSVQSVDpfglsSQFVGLDNFTALFHDSYYLDSFWTTMKFSALVT-VSGLVAS 90
Cdd:TIGR03262   1 LIARLLLAGMILALLLFLLLPLLALLTKSVYDSD-----GDFIGLANFAEYFATPGLLQSLGNSLTVSAIVTaIVVPLAF 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444   91 LFFAALVDYVVRGSRLYQTLMLLPYAVAPAVAAVLWIFLFNpGRGLITHFLAElgydwnhaqNSGQAMFLVVFASVWKQI 170
Cdd:TIGR03262  76 AFAYALTRSRIPGKGAFRLVALLPLLAPSLLPAISLIYLFG-NQGLLKGLLGG---------FSIYGFWGIVIGEVFYTF 145

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 578222444  171 SYNFLFFFAALQSIPRSLVEAAAIDGAGPVRRFFRLSLP 209
Cdd:TIGR03262 146 PHALMILVTALSLADGRLYEAARAMGASPWRTFFTVTLP 184
 
Name Accession Description Interval E-value
PRK10561 PRK10561
sn-glycerol-3-phosphate ABC transporter permease UgpA;
16-295 1.34e-170

sn-glycerol-3-phosphate ABC transporter permease UgpA;


Pssm-ID: 182550 [Multi-domain]  Cd Length: 280  Bit Score: 473.54  E-value: 1.34e-170
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444  16 LLVAPQLVITVIFFIWPAGEALWYSVQSVDPFGLSSQFVGLDNFTALFHDSYYLDSFWTTMKFSALVTVSGLVASLFFAA 95
Cdd:PRK10561   1 LLVAPQLIITVIFFIWPAGEALWYSLQSVDPFGFSSQFVGLDNFVALFHDSYYLDSFWTTIKFSTLVTVSGLLVSLFFAA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444  96 LVDYVVRGSRLYQTLMLLPYAVAPAVAAVLWIFLFNPGRGLITHFLAELGYDWNHAQNSGQAMFLVVFASVWKQISYNFL 175
Cdd:PRK10561  81 LVDYVVRGSRFYQTLMLLPYAVAPAVAAVLWIFLFNPGRGLITHFLAEFGYDWNHAQNSGQAMFLVVFASVWKQISYNFL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444 176 FFFAALQSIPRSLVEAAAIDGAGPVRRFFRLSLPLIAPVSFFLLVVNLVYAFFDTFPVIDAATAGGPVQATTTLIYKIYR 255
Cdd:PRK10561 161 FFFAALQSIPRSLVEAAAIDGAGPIRRFFKLALPLIAPVSFFLLVVNLVYAFFDTFPVIDAATSGGPVQATTTLIYKIYR 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 578222444 256 EGFAGLDLSASAAQSVVLMFLVIILTVVQFRYVESKVRYQ 295
Cdd:PRK10561 241 EGFTGLDLSSSAAQSVVLMFLVIVLTVVQFRYVESKVRYQ 280
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
2-292 1.69e-82

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 250.44  E-value: 1.69e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444   2 SSSRPVFRSRWLPYLLVAPQLVITVIFFIWPAGEALWYSVQSVDPFGLSSQFVGLDNFTALFHDSYYLDSFWTTMKFSAL 81
Cdd:COG1175    8 AARRRRRRRRLAAYLFLLPALLLLLVFVLYPLLYTLYLSFTDWNLLGPPPEFVGLDNYARLFTDPRFWNALGNTLLFTVV 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444  82 VTVSGLVASLFFAALVDYVVRGSRLYQTLMLLPYAVAPAVAAVLWIFLFNPGRGLITHFLAELGYD-WNHAQNSGQAMFL 160
Cdd:COG1175   88 SVPLQLVLGLLLALLLNRKLRGRGFFRTLFFLPWVISPVVVALIWKWLFNPDYGLLNALLGALGLEpINWLGDPSLALPA 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444 161 VVFASVWKQISYNFLFFFAALQSIPRSLVEAAAIDGAGPVRRFFRLSLPLIAPVSFFLLVVNLVYAfFDTFPVIDAATAG 240
Cdd:COG1175  168 VIIVTVWKGTGFNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGA-LQVFDLVYVLTGG 246

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|..
gi 578222444 241 GPVQATTTLIYKIYREGFAGLDLSASAAQSVVLMFLVIILTVVQFRYVESKV 292
Cdd:COG1175  247 GPGNSTTTLVLYIYQTAFQQFDFGYASAIAVVLFLIILVLTLLQLRLLRRRE 298
LplB COG4209
ABC-type polysaccharide transport system, permease component [Carbohydrate transport and ...
 9-279 3.49e-32

ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 443357 [Multi-domain]  Cd Length: 316  Bit Score: 120.97  E-value: 3.49e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444   9 RSRWLpYLLVAPQLVITVIFFIWP-AGeaLWYSVQSVDPFG--LSSQFVGLDNFTALFHDSYYLDSFWTTMKFSALVTVS 85
Cdd:COG4209   25 RDWQL-YLMLLPGLIYLLIFSYLPmYG--IVIAFKDYNPFKgiFGSPWVGLKNFKFLFSSPDFWRVLRNTLLISLLKLVF 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444  86 GLVASLFFAALVDYV--VRGSRLYQTLMLLPYAVAPAVAAVLWIFLFNPGRGLITHFLAELGYD-WNHAQNSGQAMFLVV 162
Cdd:COG4209  102 GFPLPIILALLLNELrsKRFKKTVQTISYLPHFLSWVVVAGIVYQFLSPDTGLVNQLLRALGGEpINFLTEPKYFRPIYV 181

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444 163 FASVWKQISYNFLFFFAALQSIPRSLVEAAAIDGAGPVRRFFRLSLPLIAPVSFFLLVVNL---VYAFFDTFPVIDAata 239
Cdd:COG4209  182 FSGIWKEAGWGSIIYLAAITGIDPELYEAAAIDGAGRWQQIWHITLPGIRPTIVILLILNIgniLNVGFEQIYLLYN--- 258

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 578222444 240 gGPVQATTTLI--YkIYREGFAGLDLSASAA----QSVVLMFLVII 279
Cdd:COG4209  259 -PLNYSTSDVIdtY-VYRIGLQNGDYSYATAvglfKSVVGLILVLI 302
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 5-288 1.80e-30

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 115.63  E-value: 1.80e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444   5 RPVFRSRWLPYLLVAPQLVITVIFFIWPAGEALWYSVQSVDPFGLSSQFVGLDNFTALFHDSYYLDSFWTTMKFSALVTV 84
Cdd:COG1176    2 SAALRRRLRPLLLLLPALLWLLLFFVLPLLLLLVYSFTTRDPYGGVVPGFTLENYARLFTDPLYLKVLLRTLWIALLTTL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444  85 SGLVASLFFAAlvdYVVRGSRLYQTLML----LPYAVAPAVAAVLWIFLFNPGrGLITHFLAELGYdWNHAQNSGQAMFL 160
Cdd:COG1176   82 ICLLLGYPIAY---FLARAPPRWRNLLLllviLPFWTSFLVRTYAWIVLLGRN-GLLNSLLLALGL-IDEPLRLLYTEFA 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444 161 VVFASVWKQISYNFLFFFAALQSIPRSLVEAAAIDGAGPVRRFFRLSLPLIAP--VSFFLLVVNLVYAFFDTfPVIdaat 238
Cdd:COG1176  157 VVIGLVYVYLPFMVLPLYAALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPgiIAGSLLVFIPALGAFVT-PAL---- 231

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 578222444 239 AGGPvqATTTLIYKIYREGFAGLDLSASAAQSVVLMFLVIILTVVQFRYV 288
Cdd:COG1176  232 LGGG--KVLMIGNLIYQQFLSALNWPLAAALAVVLLLIVLLVLLLYLRLL 279
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
9-291 2.72e-22

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 96.38  E-value: 2.72e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444   9 RSRWLPYLLVAPQLVITVIFFIWPAGEALWYSVQsvdpfglssqfVGLDNFTALFHDSYYLDSFWTTMKFSALVTVSGLV 88
Cdd:COG1178    4 RPRRRPRLLLLLLALLLALLVLLPLLALLLRAFT-----------DGLANFWALLSDPYLWRALGNTLLLALLVTLLSLL 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444  89 ASLFFAALVD-YVVRGSRLYQTLMLLPYAVAPAVAAVLWIFLFNPgRGLITHFLAELGyDWNHAQNSGqaMFLVVFASVW 167
Cdd:COG1178   73 LGVPLAWLLArTDFPGRRLLRWLLLLPLALPPYVVALAWIALFGP-NGLLNTLLRALF-GLEPPDIYG--LGGIILVLVL 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444 168 KQISYNFLFFFAALQSIPRSLVEAAAIDGAGPVRRFFRLSLPLIAPVSFFLLVVNLVYAFFDtFPVidAATAGGPVqatT 247
Cdd:COG1178  149 FNYPYVYLLLRAALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAAGALLVFLLCLAD-FGT--PLVLGGGY---T 222

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 578222444 248 TLIYKIYREGFAGLDLSASAAQSVVLMFLVIILTVVQFRYVESK 291
Cdd:COG1178  223 TLTTAIYQAWLGDFDLGAAAALALVLLLLVLLLLLLERRLRRRR 266
malF PRK10999
maltose ABC transporter permease MalF;
53-286 1.30e-16

maltose ABC transporter permease MalF;


Pssm-ID: 236816 [Multi-domain]  Cd Length: 520  Bit Score: 79.62  E-value: 1.30e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444  53 FVGLDNFTALFHDSY----YLDSFWTTMKFSALVTVSGLVASLFFAALVDY-VVRGSRLYQTLMLLPYAVAPAVAAVLWI 127
Cdd:PRK10999 264 TIGWKNFTRVFTDEGiqkpFIAIFIWTVVFSLLTVVLTVAVGMVLACLVQWeALKGKAVYRVLLILPYAVPSFISILIFK 343

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444 128 FLFNPGRGLITHFLAEL-GY--DWNHAQNSGQAMFLVVfaSVWKQISYNFLFFFAALQSIPRSLVEAAAIDGAGPVRRFF 204
Cdd:PRK10999 344 GLFNQSFGEINMMLSALfGIkpAWFSDPTLAKTMILIV--NTWLGYPYMMILCMGLLKAIPDDLYEASAMDGAGPFQNFF 421

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444 205 RLSLPLIAPVSFFLLVVNlvYAF-FDTFPVIDAATAGGP--VQATT---------TLIYKIYREGFAGLDLSASAAQSVV 272
Cdd:PRK10999 422 KITLPLLIKPLTPLMIAS--FAFnFNNFVLIQLLTNGGPdmIGTTTpagytdllvSYTYRIAFEGGGGQDFGLAAAIATL 499

                        250
                 ....*....|....
gi 578222444 273 LMFLVIILTVVQFR 286
Cdd:PRK10999 500 IFLLVGALAILNLK 513
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 9-293 2.65e-13

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 68.21  E-value: 2.65e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444   9 RSRWLPYLLVAPqLVITVIFFIWPAGEALWYSVQSVDPFGLSSQFVGLDNFTALFHDSYYLDSFWTTMKFSALVTVSGLV 88
Cdd:COG1177    1 SSRLGRLLLRLF-LALVLLFLYLPILVLVLYSFNDSWFLTFPPEGFTLRWYAELFSDPRLLDALLNSLLIALLSTLLATV 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444  89 ASLFFA-ALVDYVVRGSRLYQTLMLLPyavapavaavlwifLFNP----GRGLIThFLAELGYdwnhaqnsGQAMFLVVF 163
Cdd:COG1177   80 LGTPAAlALARYRFRGRRLLLALLLLP--------------LVVPgivlGVALLL-LFSALGL--------SGGLWGLIL 136

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444 164 ASVWKQISYNFLFFFAALQSIPRSLVEAAAIDGAGPVRRFFRLSLPLIAP--VSFFLLVV-----NLVYAFFdtfpvida 236
Cdd:COG1177  137 AHVVFTLPFVVLVVLARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIAPgiLAGALLAFtlsfdEFVITLF-------- 208

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 578222444 237 aTAGGpvqATTTLIYKIYREGFAGLDLSASAAqSVVLMFLVIILTVVQFRYVESKVR 293
Cdd:COG1177  209 -LAGP---GVTTLPVYIYSMIRRGISPEINAL-STLLILLSLLLLLLAERLRRRGER 260
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
9-291 7.68e-12

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 65.18  E-value: 7.68e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444   9 RSRWLPYLLVApqlVITVIFFIWPAGEALWYSVQSVDPFGLSsqfvgLDNFTALFHDSYYLDSFWTTMKFSALVTVSGLV 88
Cdd:COG1178  285 RWRWLALALCL---LLVLLGLLLPLLALLLWSLTKALDDNLT-----LDNYRFVLLDPSLLRALLNSLLLALLAALLAVL 356

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444  89 ASLFFA-ALVDYVVRGSRLYQTLMLLPYAVAPAVAAVLWIFLFNPGRGLITHflaelgydwnhaqnsgQAMFLVVFASVW 167
Cdd:COG1178  357 LALLLAyLVRRRRGRLARLLDRLAMLPYAVPGIVLGLGLLLLFNRPLPLLLY----------------GTLAILVLAYVV 420

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444 168 KQISYNFLFFFAALQSIPRSLVEAAAIDGAGPVRRFFRLSLPLIAPVsfflLVVNLVYAFFDTFPVIDAATAGGPvQATT 247
Cdd:COG1178  421 RFLPFALRSLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPG----LLAAALLVFVTSMKELSATLLLRP-PGFE 495

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 578222444 248 TLIYKIYREgFAGLDLSASAAQSVVLMFLVIILTVVQFRYVESK 291
Cdd:COG1178  496 TLAVLIYQL-ASSGRYGEAAALALLLVLVSLLPVLLLERLLGRR 538
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 1-214 4.39e-11

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 62.04  E-value: 4.39e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444   1 MSSSRPVFR---SRWLPYLLVAPQLVITVIFFIW-------PAGEalwysVQSVDPFGLSSQFvGLDNFTALFHDSYYLD 70
Cdd:COG0395    1 MSATARRRRrrlGRILLYLLLILLALLFLFPLYWmvvtsfkPPAE-----IFSGPPSLLPSEF-TLENYRAAFTDGPFGR 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444  71 SFWTtmkfSALVTVSGLVASLFFAALVDYVV-----RGSRLYQTLMLLpyavapavaavlwIFLFNPGRGLITHFLAELG 145
Cdd:COG0395   75 YLLN----SLIVAVVSTVLSLLLSSLAAYALarfrfRGRKLLFLLILA-------------TLMIPGQVLLIPLYLLFRQ 137

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 578222444 146 YDWnhaQNSGQAMFLVVFASvwkQISYNFLFFFAALQSIPRSLVEAAAIDGAGPVRRFFRLSLPLIAPV 214
Cdd:COG0395  138 LGL---LNTYWGLILPYLAF---GLPFGIFLLRQFFRSIPRELEEAARIDGASEFRIFWRIVLPLSKPA 200
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 133-294 2.71e-10

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 58.46  E-value: 2.71e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444  133 GRGLITHFLAELGYDWNHAQNSGQAMFLVVFASVWKQISYNFLFFFAALQSIPRSLVEAAAIDGAGPVRRFFRLSLPLIA 212
Cdd:pfam00528  27 LQALPSFVLAILLVVIAILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNAL 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444  213 PVSFFLLVVNLVYAFFDTFpVIDAATAGGPVQATTTLIYKIYREGFAgldlSASAAQSVVLMFLVIILTVVQFRYVESKV 292
Cdd:pfam00528 107 PPILTGLALAFGGALGGAV-LLEFLGSWPGLGLLLIEAILGYDYPEI----QGPVLAAALILLLLNLLVDILQRLLDPRV 181


                  ..
gi 578222444  293 RY 294
Cdd:pfam00528 182 RK 183
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 72-278 2.02e-08

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 53.05  E-value: 2.02e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444  72 FWTTMKFSALVTVSGLVASLFFA-ALVDYVVRGSRLYQTLMLLPYAVAPAVAAVLWIFLFnpgrglithflaelGYDWNH 150
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGiILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLF--------------GVLLGW 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444 151 AQNSGQAMFLVVFASVWkQISYNFLFFFAALQSIPRSLVEAAAIDGAGPVRRFFRLSLPLIAPVSFFLLVVNLVYAFFDT 230
Cdd:cd06261   67 GILPGLGLPALILALLL-IAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEF 145

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 578222444 231 FPVidaATAGGPVQATTTLIYKIYREGFAGLDLSASAAQSVVLMFLVI 278
Cdd:cd06261  146 ALV---SFLGGGEAPGPGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 12-209 4.98e-08

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 53.92  E-value: 4.98e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444   12 WLPYLLVAPQLVITVIFFIWPAGEALWYSVQSVDpfglsSQFVGLDNFTALFHDSYYLDSFWTTMKFSALVT-VSGLVAS 90
Cdd:TIGR03262   1 LIARLLLAGMILALLLFLLLPLLALLTKSVYDSD-----GDFIGLANFAEYFATPGLLQSLGNSLTVSAIVTaIVVPLAF 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444   91 LFFAALVDYVVRGSRLYQTLMLLPYAVAPAVAAVLWIFLFNpGRGLITHFLAElgydwnhaqNSGQAMFLVVFASVWKQI 170
Cdd:TIGR03262  76 AFAYALTRSRIPGKGAFRLVALLPLLAPSLLPAISLIYLFG-NQGLLKGLLGG---------FSIYGFWGIVIGEVFYTF 145

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 578222444  171 SYNFLFFFAALQSIPRSLVEAAAIDGAGPVRRFFRLSLP 209
Cdd:TIGR03262 146 PHALMILVTALSLADGRLYEAARAMGASPWRTFFTVTLP 184
MalG COG3833
ABC-type maltose transport system, permease component MalG [Carbohydrate transport and ...
 1-227 1.23e-06

ABC-type maltose transport system, permease component MalG [Carbohydrate transport and metabolism];


Pssm-ID: 443045 [Multi-domain]  Cd Length: 282  Bit Score: 48.99  E-value: 1.23e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444   1 MSSSRPVFRSRWLPYLLVAPQLVITVIFFIWPAgeaLWYSVQSVDPFG-LSSQF-----VGLDNFTALFHDSYYLDSFWT 74
Cdd:COG3833    1 MSRRKSRKRRRRLKLGLRHLVLIILAIIALFPI---LWVVSASFNPGGsLYSSSlipenFTLENYKKLFTETPFLRWFLN 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444  75 TMKFSALVTVsglvASLFFAALVDYV-----VRGSRLYQTLMLLpyavapavaavlwIFLFNPGRGLITHF--LAELGyd 147
Cdd:COG3833   78 SLIVAVVTAI----ISVFLAALAAYAfsrfrFKGRKAGLLALLL-------------LQMFPAFLALVALYllLSALG-- 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444 148 wnhAQNSGQAMFLVVFASvwkQISYNFLFFFAALQSIPRSLVEAAAIDGAGPVRRFFRLSLPLIAPVsfflLVVNLVYAF 227
Cdd:COG3833  139 ---LLNTLLGLILVYLGG---AIPFNTWLMKGYFDTIPKELDEAAKIDGASHFQIFFRIILPLAKPI----LAVVALLSF 208
PRK15050 PRK15050
2-aminoethylphosphonate transport system permease PhnU; Provisional
 9-213 7.36e-06

2-aminoethylphosphonate transport system permease PhnU; Provisional


Pssm-ID: 237888 [Multi-domain]  Cd Length: 296  Bit Score: 46.54  E-value: 7.36e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444   9 RSRWLPYLLVAPQLVITVIFFIWPAGEALWYSVQSVDPfglssqfVGLDNFTALFHDSYYLDSFWTTMKFSALVTVSGLV 88
Cdd:PRK15050  19 RRRLRPLLWLLLPLLVLAPLVVYPLVRVVLQSLTGEHG-------LGLATYRAVLGSPDFRGALLTTLQIAFASTAGCLV 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444  89 ASLFFAALVDYV-VRGSRLYQTLMLLPYAVAPAVAAVLWIFLFNPgRGLITHFLAELGYDWNHAQNSGQAMFLVVFAsvw 167
Cdd:PRK15050  92 LGVLLALVLAFVpFPGASLVGRFIDTFVAFPSFLITLAFTFLYGS-AGSVNIALQRLFGLEAPPLDFLYSPGGVILA--- 167

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 578222444 168 kQISYNFLF----FFAALQSIPRSLVEAAAIDGAGPVRRFFRLSLPLIAP 213
Cdd:PRK15050 168 -EITFYTPFvvrpLLAAFAQLDARQLEAAASLGASPWRVARRVILPEAWP 216
ModB COG4149
ABC-type molybdate transport system, permease component ModB [Inorganic ion transport and ...
 179-213 1.79e-05

ABC-type molybdate transport system, permease component ModB [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, permease component ModB is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443320 [Multi-domain]  Cd Length: 223  Bit Score: 45.04  E-value: 1.79e-05
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 578222444 179 AALQSIPRSLVEAAAIDGAGPVRRFFRLSLPLIAP 213
Cdd:COG4149  111 AAFEAVDPRLEEAARTLGASPWRVFFRVTLPLAKP 145
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 9-213 5.26e-04

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 40.89  E-value: 5.26e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444   9 RSRWLPYLLVAPQLVITVIFFIWPAGEALWYSVQsvdpfglssqfVGLDNFTALFHDSYYLDSFWTTMKFSALVTVSGLV 88
Cdd:COG0555    4 RVLPGFGLTLGLTLLYLSLIVLLPLAALVLKAAG-----------LGWAEFWAVLTSPRVLAALKLSLGTALIAALINLV 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578222444  89 ASLFFA-ALVDYVVRGSRLYQTLMLLPYAVAPAVAAVLWIFLFNPgRGLITHFLAELGYDWNHAQNSgqamflVVFAsvw 167
Cdd:COG0555   73 FGLPLAwVLVRYRFPGKRLVDALVDLPFALPTAVAGIALLLLFGP-NGWLGQLLAPLGIKVAFTPLG------IVLA--- 142

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 578222444 168 kqisynfLFFFA----------ALQSIPRSLVEAAAIDGAGPVRRFFRLSLPLIAP 213
Cdd:COG0555  143 -------QTFVSlpfvvrtvqpVLEELDPELEEAAATLGASRWQTFRRVILPLLLP 191
PRK10973 PRK10973
sn-glycerol-3-phosphate ABC transporter permease UgpE;
174-225 9.38e-03

sn-glycerol-3-phosphate ABC transporter permease UgpE;


Pssm-ID: 182875 [Multi-domain]  Cd Length: 281  Bit Score: 37.02  E-value: 9.38e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 578222444 174 FLF--FFAALqsiPRSLVEAAAIDGAGPVRRFFRLSLPLIAPVSFFLLVVNLVY 225
Cdd:PRK10973 160 FLFrqFFMTL---PDELVEAARIDGASPMRFFWDIVLPLSKTNLAALFVITFIY 210
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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