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Conserved domains on  [gi|578270525|gb|EUM30452|]
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allantoate transport membrane protein [Enterobacter sp. BIDMC 26]

Protein Classification

amino acid ABC transporter permease( domain architecture ID 11433582)

amino acid ABC transporter permease is the transmembrane (TM) subunit of a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter which binds and transports amino acids

Gene Ontology:  GO:0140359|GO:0042626|GO:0006865
PubMed:  25750732|24638992
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HisM COG0765
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 4-216 3.89e-77

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


:

Pssm-ID: 440528 [Multi-domain]  Cd Length: 218  Bit Score: 231.12  E-value: 3.89e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525   4 QLHFSALWPYWPALLAGLWVTIQLTVMATLGGLAIGIFGAAIRSGRTTWFSRIWGGYVEIIRNTPFVVQLFFIVFGLPNL 83
Cdd:COG0765    2 FFDFSVLLDYLPLLLEGLLVTLLLTVLAIVLGLVLGLLLALARLSPNPVLRWLATAYVEFFRGTPLLVQLFFIYFGLPLL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525  84 GLKMTAGEAALLAMVVNLGAYSTEIVRAGIQVTPKGQWEAGRVLGLTRLQTFIRVVLPPALQRIYPALVSQCIIVMLGSS 163
Cdd:COG0765   82 GIDLSPFVAAVIALTLNSAAYLAEIVRAGIQSVPKGQWEAARALGLSRWQTMRRIILPQALRIILPPLGNEFISLLKDTS 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 578270525 164 VVSQVSYEELTFAANLIQSRTFLSFEVYLVTTGIYLVLSITLRQLMMAAGRKW 216
Cdd:COG0765  162 LVSVIGVPELTRAAQQIASRTFRPFEVYLVAALIYLVLTLPLSLLARRLERRL 214
 
Name Accession Description Interval E-value
HisM COG0765
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 4-216 3.89e-77

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440528 [Multi-domain]  Cd Length: 218  Bit Score: 231.12  E-value: 3.89e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525   4 QLHFSALWPYWPALLAGLWVTIQLTVMATLGGLAIGIFGAAIRSGRTTWFSRIWGGYVEIIRNTPFVVQLFFIVFGLPNL 83
Cdd:COG0765    2 FFDFSVLLDYLPLLLEGLLVTLLLTVLAIVLGLVLGLLLALARLSPNPVLRWLATAYVEFFRGTPLLVQLFFIYFGLPLL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525  84 GLKMTAGEAALLAMVVNLGAYSTEIVRAGIQVTPKGQWEAGRVLGLTRLQTFIRVVLPPALQRIYPALVSQCIIVMLGSS 163
Cdd:COG0765   82 GIDLSPFVAAVIALTLNSAAYLAEIVRAGIQSVPKGQWEAARALGLSRWQTMRRIILPQALRIILPPLGNEFISLLKDTS 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 578270525 164 VVSQVSYEELTFAANLIQSRTFLSFEVYLVTTGIYLVLSITLRQLMMAAGRKW 216
Cdd:COG0765  162 LVSVIGVPELTRAAQQIASRTFRPFEVYLVAALIYLVLTLPLSLLARRLERRL 214
PRK15100 PRK15100
cystine ABC transporter permease;
15-208 1.35e-35

cystine ABC transporter permease;


Pssm-ID: 185055 [Multi-domain]  Cd Length: 220  Bit Score: 125.25  E-value: 1.35e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525  15 PALLAGLWVTIQLTVMATLGGLAIGIFGAAIRSGRT---TWFSRIwggYVEIIRNTPFVVQLFFIVFGLPNLGLKMTAGE 91
Cdd:PRK15100  13 PFLLKGAGYTLQLSIGGMFFGLLLGFILALMRLSPIwpvRWLARF---YVSIFRGTPLIAQLFMIYYGLPQFGIELDPIP 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525  92 AALLAMVVNLGAYSTEIVRAGIQVTPKGQWEAGRVLGLTRLQTFIRVVLPPALQRIYPALVSQCIIVMLGSSVVSQVSYE 171
Cdd:PRK15100  90 AAMIGLSLNTAAYAAETLRAAISSIDKGQWEAAASIGMTRWQTLRRAILPQAARTALPPLSNSFISLVKDTSLAATIQVP 169

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 578270525 172 ELTFAANLIQSRTFLSFEVYLVTTGIYLVLSITLRQL 208
Cdd:PRK15100 170 ELFRQAQLITSRTLEVFTMYLAASLIYWIMATVLSAL 206
ectoine_ehuD TIGR03003
ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Members of this family are ...
 15-205 2.66e-34

ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Members of this family are presumed to act as permease subunits of ectoine ABC transporters. Operons containing this gene also contain the other genes of the ABC transporter and typically are found next to either ectoine utilization or ectoine biosynthesis operons.


Pssm-ID: 132048 [Multi-domain]  Cd Length: 212  Bit Score: 121.50  E-value: 2.66e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525   15 PALLAGLWVTIQLTVMATLGGLAIGIFGAAIRSGRTTWFSRIWGGYVEIIRNTPFVVQLFFIVFGLPNLGLKMTAGEAAL 94
Cdd:TIGR03003  11 PTLIEGLKITILATALGFAIAAVLGLVFAILRRSAPTPISWPTSFVVEFIRGTPLLVQLYFLYYVLPDIGIRLPALVAGV 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525   95 LAMVVNLGAYSTEIVRAGIQVTPKGQWEAGRVLGLTRLQTFIRVVLPPALQRIYPALVSQCIIVMLGSSVVSQVSYEELT 174
Cdd:TIGR03003  91 LGLGLHYATYAAEVYRAGIEAVPRGQWEAATALNLTARQTYRHIILPQAIPPIIPALGNYLVAMFKETPVLSAITVLELM 170

                         170       180       190
                  ....*....|....*....|....*....|.
gi 578270525  175 FAANLIQSRTFLSFEVYLVTTGIYLVLSITL 205
Cdd:TIGR03003 171 NQAKSIGNSTFRYLEPMTLVGVFFLILSIIS 201
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 21-203 2.32e-16

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 73.85  E-value: 2.32e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525  21 LWVTIQLTVMATLGGLAIGIFGAAIRSGRTTWFSRIWGGYVEIIRNTPFVVQLFFIVFGLPNLG---LKMTAGEAALLAM 97
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLgwgILPGLGLPALILA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525  98 VVNLGAYSTEIVRAGIQVTPKGQWEAGRVLGLTRLQTFIRVVLPPALQRIYPALVSQCIIVMLGSSVVSQVSYEELTFAA 177
Cdd:cd06261   81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPG 160

                        170       180
                 ....*....|....*....|....*.
gi 578270525 178 NLIQSRTFLSFEVYLVTTGIYLVLSI 203
Cdd:cd06261  161 TGLLLIFAILFPGDLGVAAAVALILL 186
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 35-203 2.41e-10

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 57.31  E-value: 2.41e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525   35 GLAIGIFGAAIRSGrttWFSRIWGGYVEIIRNTPFVVQLFFIVFGLPNLGLKmTAGEAALLAMVVNLGAYSTEIVRAGIQ 114
Cdd:pfam00528   1 GIPLGIIAALRRGR---RLDRLLRPLIDLLQALPSFVLAILLVVIAILSILG-HGILPAIILALLGWAGYARLIRRAALR 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525  115 VTPKGQWEAGRVLGLTRLQTFIRVVLPPALQRIYPALVSQCIIVMLGSSVVSQV---SYEELTFAANLIQSRTFLSFEVY 191
Cdd:pfam00528  77 SLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLgswPGLGLLLIEAILGYDYPEIQGPV 156

                         170
                  ....*....|..
gi 578270525  192 LVTTGIYLVLSI 203
Cdd:pfam00528 157 LAAALILLLLNL 168
 
Name Accession Description Interval E-value
HisM COG0765
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 4-216 3.89e-77

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440528 [Multi-domain]  Cd Length: 218  Bit Score: 231.12  E-value: 3.89e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525   4 QLHFSALWPYWPALLAGLWVTIQLTVMATLGGLAIGIFGAAIRSGRTTWFSRIWGGYVEIIRNTPFVVQLFFIVFGLPNL 83
Cdd:COG0765    2 FFDFSVLLDYLPLLLEGLLVTLLLTVLAIVLGLVLGLLLALARLSPNPVLRWLATAYVEFFRGTPLLVQLFFIYFGLPLL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525  84 GLKMTAGEAALLAMVVNLGAYSTEIVRAGIQVTPKGQWEAGRVLGLTRLQTFIRVVLPPALQRIYPALVSQCIIVMLGSS 163
Cdd:COG0765   82 GIDLSPFVAAVIALTLNSAAYLAEIVRAGIQSVPKGQWEAARALGLSRWQTMRRIILPQALRIILPPLGNEFISLLKDTS 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 578270525 164 VVSQVSYEELTFAANLIQSRTFLSFEVYLVTTGIYLVLSITLRQLMMAAGRKW 216
Cdd:COG0765  162 LVSVIGVPELTRAAQQIASRTFRPFEVYLVAALIYLVLTLPLSLLARRLERRL 214
PRK15100 PRK15100
cystine ABC transporter permease;
15-208 1.35e-35

cystine ABC transporter permease;


Pssm-ID: 185055 [Multi-domain]  Cd Length: 220  Bit Score: 125.25  E-value: 1.35e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525  15 PALLAGLWVTIQLTVMATLGGLAIGIFGAAIRSGRT---TWFSRIwggYVEIIRNTPFVVQLFFIVFGLPNLGLKMTAGE 91
Cdd:PRK15100  13 PFLLKGAGYTLQLSIGGMFFGLLLGFILALMRLSPIwpvRWLARF---YVSIFRGTPLIAQLFMIYYGLPQFGIELDPIP 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525  92 AALLAMVVNLGAYSTEIVRAGIQVTPKGQWEAGRVLGLTRLQTFIRVVLPPALQRIYPALVSQCIIVMLGSSVVSQVSYE 171
Cdd:PRK15100  90 AAMIGLSLNTAAYAAETLRAAISSIDKGQWEAAASIGMTRWQTLRRAILPQAARTALPPLSNSFISLVKDTSLAATIQVP 169

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 578270525 172 ELTFAANLIQSRTFLSFEVYLVTTGIYLVLSITLRQL 208
Cdd:PRK15100 170 ELFRQAQLITSRTLEVFTMYLAASLIYWIMATVLSAL 206
glnP PRK09494
glutamine ABC transporter permease protein; Reviewed
 4-208 7.65e-35

glutamine ABC transporter permease protein; Reviewed


Pssm-ID: 181907 [Multi-domain]  Cd Length: 219  Bit Score: 123.24  E-value: 7.65e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525   4 QLHFSALWPYWPALLAGLWVTIQLTVMATLGGLAIGIFGAAIRSGRTTWFSRIWGGYVEIIRNTPFVVQLFFIVFGLPNL 83
Cdd:PRK09494   2 QFDWSAIWPAIPLLLEGAKMTLWISVLGLAGGLVIGLLAGFARAYGGWIANHIALVFIELIRGTPIVVQVMFIYFALPMA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525  84 --GLKMTAGEAALLAMVVNLGAYSTEIVRAGIQVTPKGQWEAGRVLGLTRLQTFIRVVLPPALQRIYPALVSQCIIVMLG 161
Cdd:PRK09494  82 fnDLRIDPFTAAVVTIMINSGAYIAEITRGAVLSIHKGFREAGLALGLSRRETLRYVIGPLALRRMLPPLGNQWIISIKD 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 578270525 162 SSVVSQVSYEELTFAANLIQSRTFLSFEVYLVTTGIYL----VLSITLRQL 208
Cdd:PRK09494 162 TSLFIVIGVAELTRQGQEIIAGNFRALEIWSAVAVIYLiitlVLSFILRRL 212
ectoine_ehuD TIGR03003
ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Members of this family are ...
 15-205 2.66e-34

ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Members of this family are presumed to act as permease subunits of ectoine ABC transporters. Operons containing this gene also contain the other genes of the ABC transporter and typically are found next to either ectoine utilization or ectoine biosynthesis operons.


Pssm-ID: 132048 [Multi-domain]  Cd Length: 212  Bit Score: 121.50  E-value: 2.66e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525   15 PALLAGLWVTIQLTVMATLGGLAIGIFGAAIRSGRTTWFSRIWGGYVEIIRNTPFVVQLFFIVFGLPNLGLKMTAGEAAL 94
Cdd:TIGR03003  11 PTLIEGLKITILATALGFAIAAVLGLVFAILRRSAPTPISWPTSFVVEFIRGTPLLVQLYFLYYVLPDIGIRLPALVAGV 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525   95 LAMVVNLGAYSTEIVRAGIQVTPKGQWEAGRVLGLTRLQTFIRVVLPPALQRIYPALVSQCIIVMLGSSVVSQVSYEELT 174
Cdd:TIGR03003  91 LGLGLHYATYAAEVYRAGIEAVPRGQWEAATALNLTARQTYRHIILPQAIPPIIPALGNYLVAMFKETPVLSAITVLELM 170

                         170       180       190
                  ....*....|....*....|....*....|.
gi 578270525  175 FAANLIQSRTFLSFEVYLVTTGIYLVLSITL 205
Cdd:TIGR03003 171 NQAKSIGNSTFRYLEPMTLVGVFFLILSIIS 201
ectoine_ehuC TIGR03004
ectoine/hydroxyectoine ABC transporter, permease protein EhuC; Members of this family are ...
 13-209 5.17e-30

ectoine/hydroxyectoine ABC transporter, permease protein EhuC; Members of this family are presumed to act as permease subunits of ectoine ABC transporters. Operons containing this gene also contain the other genes of the ABC transporter and typically are found next to either ectoine utilization or ectoine biosynthesis operons. Permease subunits EhuC and EhuD are homologous.


Pssm-ID: 132049 [Multi-domain]  Cd Length: 214  Bit Score: 110.71  E-value: 5.17e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525   13 YWPALLAGLWVTIQLTVMATLGGLAIGIFGAAIRSGRTTWFSRIWGGYVEIIRNTPFVVQLFFIVFGLPNLGLKMTAGEA 92
Cdd:TIGR03004   3 YLPLLLQGAWVTMQITLAGSVLATVLAFFAGLGRVSGGPILRTVALCYIEVFRGTSLLVQLFWFYFVLPLIGLSLDPVTT 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525   93 ALLAMVVNLGAYSTEIVRAGIQVTPKGQWEAGRVLGLTRLQTFIRVVLPPALQRIYPALVSQCIIVMLGSSVVSQVSYEE 172
Cdd:TIGR03004  83 GVMVLGLHAGAYGAEIVRGALSSVSVQQLEACRALNFTRFQTLRRISLPQALVEMMPAFGNLAIELLKLTSLVSLISLAD 162

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 578270525  173 LTFAANLIQSRTFLSFEVYLVTTGIYLVLSITLRQLM 209
Cdd:TIGR03004 163 LTFAAQSIRNLTLDTLSIFAITLLCYFVMALIIMLIM 199
HEQRo_perm_3TM TIGR01726
amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; This ...
 13-111 8.68e-22

amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; This model represents one of several classes of multiple membrane spanning regions found immediately N-terminal to the domain described by pfam00528, binding-protein-dependent transport systems inner membrane component. The region covered by this model generally is predicted to contain three transmembrane helices. Substrate specificities attributed to members of this family include histidine, arginine, glutamine, glutamate, and (in Agrobacterium) the opines octopine and nopaline. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 130787 [Multi-domain]  Cd Length: 99  Bit Score: 85.66  E-value: 8.68e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525   13 YWPALLAGLWVTIQLTVMATLGGLAIGIFGAAIRSGRTTWFSRIWGGYVEIIRNTPFVVQLFFIVFGLPNLGLKMTAGEA 92
Cdd:TIGR01726   1 NLPFLLKGLLLTLLLSVLSILLGLVLGLLLALLRLSGNRPLRWIATVYVELFRGTPLLVQLFFIYFGLPLIGIRLSPLTA 80

                          90
                  ....*....|....*....
gi 578270525   93 ALLAMVVNLGAYSTEIVRA 111
Cdd:TIGR01726  81 AVIALTLFYGAYLAEIFRG 99
artM PRK11122
arginine ABC transporter permease ArtM;
10-208 2.87e-21

arginine ABC transporter permease ArtM;


Pssm-ID: 182978 [Multi-domain]  Cd Length: 222  Bit Score: 87.71  E-value: 2.87e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525  10 LWPYWPALLAGLWVTIQLTVMATLGGLAIGIFGAAIRSGRTTWFSRIWGGYVEIIRNTPFVVQLFFIVFG---------L 80
Cdd:PRK11122   1 MLEYLPELLKGLHTSLTLTVASLLVALVLALIFTIILTLKTPVLVWLVRGYITLFTGTPLLVQIFLIYYGpgqfpwlqeY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525  81 PNL-GLKMTAGEAALLAMVVNLGAYSTEIVRAGIQVTPKGQWEAGRVLGLTRLQTfIRVVLPPALQRIYPALVSQCIIVM 159
Cdd:PRK11122  81 PWLwHLLSQPWLCAMLALALNSAAYSTQLFYGAVRAIPEGQWQSCAALGMSKKQT-LRILLPYAFKRALSSYSNEVVLVF 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 578270525 160 LGSSVVSQVSYEELTFAANLIQSRTFlSFEVYLVTTGIYL----VLSITLRQL 208
Cdd:PRK11122 160 KSTSLAYTITLMDVMGYSQLLYGRTY-DVMVFGAAGIIYLvvngLLTLLMRLI 211
PRK11123 PRK11123
arginine ABC transporter permease ArtQ;
17-205 5.58e-21

arginine ABC transporter permease ArtQ;


Pssm-ID: 182979 [Multi-domain]  Cd Length: 238  Bit Score: 87.43  E-value: 5.58e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525  17 LLAGLWVTIQLTVMATLGGLAIGIFGAAIRSGRTTWFSRIWGGYVEIIRNTPFVVQLFFIVFGLPNLGLKMTAG------ 90
Cdd:PRK11123   7 LASAAGMTVGLAVCALIVGLALAMLFAVWESAKWRPVAWPGTALVTLLRGLPEILVVLFIYFGSSQLLLTLSDGftlnlg 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525  91 --------------EAALLAMVVNL----GAYSTEIVRAGIQVTPKGQWEAGRVLGLTRLQTFIRVVLPPALQRIYPALV 152
Cdd:PRK11123  87 fvqipvqmdienfeVSPFLCGVIALsllyAAYASQTLRGALKAVPVGQWESGQALGLSKSAIFFRLVMPQMWRHALPGLG 166

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 578270525 153 SQCIIVMLGSSVVSQVSYEELTFAANLIQSRTFLSFEVYLVTTGIYLVlsITL 205
Cdd:PRK11123 167 NQWLVLLKDTALVSLISVNDLMLQTKSIATRTQEPFTWYIIAAAIYLV--ITL 217
PRK15069 PRK15069
histidine ABC transporter permease HisM;
13-217 1.05e-20

histidine ABC transporter permease HisM;


Pssm-ID: 185029 [Multi-domain]  Cd Length: 234  Bit Score: 86.64  E-value: 1.05e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525  13 YWPALL-------AGLWVTIQLTVMATLGGLAIGIFGAAIRSGRTTWFSRIWGGYVEIIRNTPFVVQLFFIVFGLPNLGL 85
Cdd:PRK15069   8 YWKALLwtdgyrfTGLAITLWLLVASVVIGFVLAVPLAIARVSSNKWIRFPVWLYTYVFRGTPLYVQLLVFYTGMYSLEI 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525  86 K----------MTAGEAALLAMVVNLGAYSTEIVRAGIQVTPKGQWEAGRVLGLTRLQTFIRVVLPPALQRIYPALVSQC 155
Cdd:PRK15069  88 VrgtdlldaffRSGLNCTILAFTLNTCAYTTEIFAGAIRSVPHGEIEAARAYGMSTFKLYRRIILPSALRRALPAYSNEV 167

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 578270525 156 IIVMLGSSVVSQVSYEELTFAANLIQSRTFLSFEVYLVTTGIYLVLSITLRQLMMAAGRKWL 217
Cdd:PRK15069 168 ILMLHATTLAFTATVPDILKIARDINSATYQPFQAFGIAAVLYLIISFVLISLFRRAERRWL 229
BatB COG4597
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 92-209 4.00e-17

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 443651 [Multi-domain]  Cd Length: 397  Bit Score: 79.03  E-value: 4.00e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525  92 AALLAMVVNLGAYSTEIVRAGIQVTPKGQWEAGRVLGLTRLQTFIRVVLPPALQRIYPALVSQCIIVMLGSSVVSQVSYE 171
Cdd:COG4597  267 ALLLALSLYTAAFIAEIVRAGIQAVSKGQTEAARALGLRPGQTLRLVVLPQALRVIIPPLTSQYLNLTKNSSLAVAIGYP 346

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 578270525 172 ELTF-AANLIQSRTFLSFEVYLVTTGIYLVLSITLRQLM 209
Cdd:COG4597  347 DLVSvFAGTTLNQTGQAIEIIAITMAVYLTISLLISLLM 385
PRK15107 PRK15107
glutamate/aspartate ABC transporter permease GltK;
4-209 1.40e-16

glutamate/aspartate ABC transporter permease GltK;


Pssm-ID: 185062 [Multi-domain]  Cd Length: 224  Bit Score: 75.25  E-value: 1.40e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525   4 QLHFSALWPYWPALLAGLWVTIQLTVMATLGGLAIGIFGAAIRSGR---TTWFSRIwggYVEIIRNTPFVVQLFFIVFGL 80
Cdd:PRK15107   3 EFDWSSIVPSLPYLLDGLVITLKITVTAVVIGILWGTILAVMRLSSfkpVAWFAKA---YVNVFRSIPLVMVLLWFYLIV 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525  81 PN-----LGLKMTAGEAALLAMV---VNLGAYSTEIVRAGIQVTPKGQWEAGRVLGLTRLQTFIRVVLPPALQRIYPALV 152
Cdd:PRK15107  80 PGflqnvLGLSPKTDIRLISAMVafsMFEAAYYSEIIRAGIQSISRGQSSAALALGMTHWQSMKLIILPQAFRAMVPLLL 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 578270525 153 SQCIIVMLGSSVVSQVSYEELTFAANLIQSRTFLSFEVYLVTTGIYLVLSITLRQLM 209
Cdd:PRK15107 160 TQGIVLFQDTSLVYVLSLADFFRTASTIGERDGTQVEMILFAGFVYFVISLSASLLV 216
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 21-203 2.32e-16

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 73.85  E-value: 2.32e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525  21 LWVTIQLTVMATLGGLAIGIFGAAIRSGRTTWFSRIWGGYVEIIRNTPFVVQLFFIVFGLPNLG---LKMTAGEAALLAM 97
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLgwgILPGLGLPALILA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525  98 VVNLGAYSTEIVRAGIQVTPKGQWEAGRVLGLTRLQTFIRVVLPPALQRIYPALVSQCIIVMLGSSVVSQVSYEELTFAA 177
Cdd:cd06261   81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPG 160

                        170       180
                 ....*....|....*....|....*.
gi 578270525 178 NLIQSRTFLSFEVYLVTTGIYLVLSI 203
Cdd:cd06261  161 TGLLLIFAILFPGDLGVAAAVALILL 186
PRK15135 PRK15135
histidine ABC transporter permease HisQ;
10-202 9.33e-13

histidine ABC transporter permease HisQ;


Pssm-ID: 185089 [Multi-domain]  Cd Length: 228  Bit Score: 64.81  E-value: 9.33e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525  10 LWPYWPALLAGLWVTIQLTVMATLGGLAIGIFGAAIRSGRTTWFSRIWGGYVEIIRNTPFVVQLFFIVFGLP-------- 81
Cdd:PRK15135   2 LYGFSGVILQGALVTLELALSSVVLAVIIGLIGAGGKLSQNRLLGLIFEGYTTLIRGVPDLVLMLLIFYGLQialnsvte 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525  82 NLGLK------MTAGeaaLLAMVVNLGAYSTEIVRAGIQVTPKGQWEAGRVLGLTRLQTFIRVVLPPALQRIYPALVSQC 155
Cdd:PRK15135  82 ALGVGqididpMVAG---IITLGFIYGAYFTETFRGAFMAVPKGHIEAATAFGFTRGQVFRRIMFPAMMRYALPGIGNNW 158

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 578270525 156 IIVMLGSSVVSQVSYEELTFAANLIQSRTFLSFEVYLVTTGIYLVLS 202
Cdd:PRK15135 159 QVILKATALVSLLGLEDVVKATQLAGKSTWEPFYFAIVCGVIYLVFT 205
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 35-203 2.41e-10

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 57.31  E-value: 2.41e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525   35 GLAIGIFGAAIRSGrttWFSRIWGGYVEIIRNTPFVVQLFFIVFGLPNLGLKmTAGEAALLAMVVNLGAYSTEIVRAGIQ 114
Cdd:pfam00528   1 GIPLGIIAALRRGR---RLDRLLRPLIDLLQALPSFVLAILLVVIAILSILG-HGILPAIILALLGWAGYARLIRRAALR 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525  115 VTPKGQWEAGRVLGLTRLQTFIRVVLPPALQRIYPALVSQCIIVMLGSSVVSQV---SYEELTFAANLIQSRTFLSFEVY 191
Cdd:pfam00528  77 SLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLgswPGLGLLLIEAILGYDYPEIQGPV 156

                         170
                  ....*....|..
gi 578270525  192 LVTTGIYLVLSI 203
Cdd:pfam00528 157 LAAALILLLLNL 168
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
 14-217 2.01e-08

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 52.84  E-value: 2.01e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525  14 WPALLAGLWVTIQLTVMATLGGLAIGIFGAAIrSGRTTWFSRIWGGYVEIIRNTPFV--VQLFFIVFGLPNLGLKMTAGE 91
Cdd:COG0600   56 SGELWEHLLASLLRVLLGFALAALLGVPLGLL-LGLSRLLRRLLDPLLVFLRPIPPLalAPLLILWFGIGEASKIFVIFL 134

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525  92 AALLAMVVNlgaysteiVRAGIQVTPKGQWEAGRVLGLTRLQTFIRVVLPPALQRIYPALvsqciIVMLGSSVVSQVSYE 171
Cdd:COG0600  135 GAFFPILLN--------TAAGVRSVDPELLELARSLGASRWQILRKVVLPAALPYIFTGL-----RIALGLAWIGLVVAE 201

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 578270525 172 elTFAAN------LIQSRTFLSFEVYLVTTGIYLVLSITLRQLMMAAGRKWL 217
Cdd:COG0600  202 --LLGASsglgylILDARQLLDTDLVFAAILVIGLLGLLLDLLLRLLERRLL 251
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
6-160 1.08e-06

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 48.62  E-value: 1.08e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525   6 HFSALWPYW--PALLAGLWVTIQLTVMATLGGLAIGIFGAAIRSGRTTWFSRIWG----------------GYVEIIRNT 67
Cdd:COG1178   39 GLANFWALLsdPYLWRALGNTLLLALLVTLLSLLLGVPLAWLLARTDFPGRRLLRwllllplalppyvvalAWIALFGPN 118

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525  68 PFVVQLFFIVFGLPNLGLKMTAGeaALLAMVVNLGAYSTEIVRAGIQVTPKGQWEAGRVLGLTRLQTFIRVVLPPALqri 147
Cdd:COG1178  119 GLLNTLLRALFGLEPPDIYGLGG--IILVLVLFNYPYVYLLLRAALRSIDASLEEAARSLGASPWRAFRRVTLPLLR--- 193

                        170
                 ....*....|...
gi 578270525 148 yPALVSQCIIVML 160
Cdd:COG1178  194 -PAIAAGALLVFL 205
PhnE COG3639
ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport ...
 7-156 7.40e-05

ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 442856 [Multi-domain]  Cd Length: 244  Bit Score: 42.38  E-value: 7.40e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525   7 FSALWPYWPALLAGLWVTIQLTVMATLGGLAIGI---FGAAIRSGRTTWFSRIWGGYVEIIRNTPFVV--QLFFIVFGLP 81
Cdd:COG3639   39 FPPDWSYLPDLLSALLETLAIALLGTLLGAVLALplaFLAARNLAPNPWVRLLARRLLNVLRAIPELVwaLIFVAAVGLG 118

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 578270525  82 NLglkmtageAALLAMVVNLGAYSTEIVRAGIQVTPKGQWEAGRVLGLTRLQTFIRVVLPpalqRIYPALVSQCI 156
Cdd:COG3639  119 PF--------AGVLALAIHTIGFLGKLFAEAIEEIDPGPVEALRATGASRLQVIRYGVLP----QVLPQFLSYTL 181
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
15-141 4.81e-04

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 40.53  E-value: 4.81e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525  15 PALLAGLWVTIQLTVMATLGGLAIGIFGAAIRSGRTTWFSRIWGGYVEIIRNTP-FVVQLFFIVFGLPNLGLKMTAGEAA 93
Cdd:COG1178  334 PSLLRALLNSLLLALLAALLAVLLALLLAYLVRRRRGRLARLLDRLAMLPYAVPgIVLGLGLLLLFNRPLPLLLYGTLAI 413

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 578270525  94 L-LAMVVNLGAYSTEIVRAGIQVTPKGQWEAGRVLGLTRLQTFIRVVLP 141
Cdd:COG1178  414 LvLAYVVRFLPFALRSLEAALAQIDPSLEEAARSLGASPLRTLRRVTLP 462
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 15-162 6.59e-04

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 39.71  E-value: 6.59e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525  15 PALLAGLWVTIQLTVMATLGGLAIGIFGA-AIRSGRttwfsRIWGGYVEIIRNTPFVVQL------FFIVFGLPNLGLKM 87
Cdd:COG1177   57 PRLLDALLNSLLIALLSTLLATVLGTPAAlALARYR-----FRGRRLLLALLLLPLVVPGivlgvaLLLLFSALGLSGGL 131

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 578270525  88 TAgeaALLAMVVNLGAYSTEIVRAGIQVTPKGQWEAGRVLGLTRLQTFIRVVLPpalqRIYPALVSQCIIVMLGS 162
Cdd:COG1177  132 WG---LILAHVVFTLPFVVLVVLARLQGFDPSLEEAARDLGASPWQTFRRVTLP----LIAPGILAGALLAFTLS 199
PhnE TIGR01097
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound ...
 11-154 1.77e-03

phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions]


Pssm-ID: 273441 [Multi-domain]  Cd Length: 250  Bit Score: 38.29  E-value: 1.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525   11 WPYWPALLAGLWVTIQLTVMATLGGLAIGIFGAAIRSGRTT---WFSRIWGGYVEIIRNTPFVV--QLFFIVFGLpnlgl 85
Cdd:TIGR01097  50 WSYLPRILKALLETLAMAILGTVLAAVLAVPLALLAARNITpspWLYGLARLLLNFLRAIPELVwaLIFVAAVGL----- 124

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 578270525   86 kmtAGEAALLAMVVNLGAYSTEIVRAGIQVTPKGQWEAGRVLGLTRLQTFIRVVLPPALqriyPALVSQ 154
Cdd:TIGR01097 125 ---GPFAGVLALAFHTVGFLGKLFAEAIEEVDPGPVEALRATGASKLQVIRYGVLPQVL----PQFLSY 186
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 2-153 9.40e-03

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 36.27  E-value: 9.40e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525   2 TEQLHFSALWPYW--PALLAGLWVTIQLTVMATLGGLAIGIFGAAIRSGRTTWFSRIwggyVEIIRNTPFVVQ------L 73
Cdd:COG0555   35 AAGLGWAEFWAVLtsPRVLAALKLSLGTALIAALINLVFGLPLAWVLVRYRFPGKRL----VDALVDLPFALPtavagiA 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578270525  74 FFIVFG--------LPNLGLKMTAGEAA-LLAMV-VNLgAYSTEIVRAGIQVTPKGQWEAGRVLGLTRLQTFIRVVLPPA 143
Cdd:COG0555  111 LLLLFGpngwlgqlLAPLGIKVAFTPLGiVLAQTfVSL-PFVVRTVQPVLEELDPELEEAAATLGASRWQTFRRVILPLL 189

                        170
                 ....*....|
gi 578270525 144 LqriyPALVS 153
Cdd:COG0555  190 L----PALLT 195
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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