|
Name |
Accession |
Description |
Interval |
E-value |
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
4-1115 |
0e+00 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 1829.53 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 4 TNRSQHPVLVFLLATLFFFATAPLSWARADNNNDIPSRSDVQSQLDTLNKQKDLSALDKLVQQDLTETLETLDKIERVKA 83
Cdd:PRK11281 1 YKRSRHFVFRAFIAFLFLLLCLSSAFARAASNGDLPTEADVQAQLDALNKQKLLEAEDKLVQQDLEQTLALLDKIDRQKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 84 ETTQLRQKVAQAPENMRKATESLNALSDvDNDDETRKTLATLSLRQLESRVAQLLDDLQTAQSDLGTYNSQLVSLQTQPE 163
Cdd:PRK11281 81 ETEQLKQQLAQAPAKLRQAQAELEALKD-DNDEETRETLSTLSLRQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 164 RVQNAMYAASQQLQQIRNRLNGTSVGEGTLRPTQQTLLLVQQALLNAQIEQQRKSLEGNTVLQDTLQKQRDYVTANINRL 243
Cdd:PRK11281 160 RAQAALYANSQRLQQIRNLLKGGKVGGKALRPSQRVLLQAEQALLNAQNDLQRKSLEGNTQLQDLLQKQRDYLTARIQRL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 244 EHQLQLLQEAVNSKRLTLTEKTAQEAVSPDETARIQANPLVKQELEANHQLSQRLIVATESGNSLVQQNIRVKNWLDRAL 323
Cdd:PRK11281 240 EHQLQLLQEAINSKRLTLSEKTVQEAQSQDEAARIQANPLVAQELEINLQLSQRLLKATEKLNTLTQQNLRVKNWLDRLT 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 324 QAERNIKEQIAVLKGSLLLSRILYQQQQTLPSADELEDMTNRIADLRLEQFDVNQQRDALFQSDTFVAKLEEGHSSEVNP 403
Cdd:PRK11281 320 QSERNIKEQISVLKGSLLLSRILYQQQQALPSADLIEGLADRIADLRLEQFEINQQRDALFQPDAYIDKLEAGHKSEVTD 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 404 EVHDALLQVVDMRRELLDQLNKQLGNQLMMAINLQINQQQLVSVSKSLQEILTQQIFWVNSNKPMDWDWIKSFPETLKAQ 483
Cdd:PRK11281 400 EVRDALLQLLDERRELLDQLNKQLNNQLNLAINLQLNQQQLLSVSDSLQSTLTQQIFWVNSNKPMDLDWLKAFPQALKDQ 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 484 IKSMKITVNWEKAWPAVMIAFLAGLPLLLIAGLIRWRLGWLKKYQDKLASEVGQLRNDSQLHTPKAILIDLIRALPVCLI 563
Cdd:PRK11281 480 FKSLKITVSFSNLWDGLFIALLLFLPLLLIAGLIRWRKKWIKARLQKLAADIGTLKRDSQLHTPKAILITLLLALPVTLI 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 564 ILAVGLILLTMQLNISDLLWAFSKKLALFWLVFGVCWKVLEKDGVAVRHFNMPAQLTSHWRRQIVRVSLALLPLHFWSVV 643
Cdd:PRK11281 560 FLAVGLILLTDAFNQSELLWSWSLKLALFWLVFATCYRVLRPNGVAERHFGMPKEQVSHFRRQIVRLSLALLPLLFWSVV 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 644 AELSPLHLMDDVMGQLVILLNLLLIAILMWPMCRDSWRDKESHNIRLATVTVLAIIPLALMVLTATGYFYTTLRLSGRWI 723
Cdd:PRK11281 640 AELSPLGLADDVIGQAVIIIALALIAFLVWPLCRESWRDKESHTLRLVVRTVLTIAPIALIVLVVLGYYYTALRLIGRLI 719
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 724 ETVYLVIVWNLLYQTVLRGLSVAARRIAYRRAIARRQHQVKEGAEGAEPQEEPTIALEQVNQQTLRITMLVMIALFAVMF 803
Cdd:PRK11281 720 ETLYLLIIWNLLYQTVLRGLSVAARRLAYRRALAKRQNLVKEGAEGAEPVEEPTLALEQVNQQSLRLTDLLLFALFFVMF 799
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 804 WAIWSDLITVFAYLDSITLWQYNGTEAGAAVMKSVTMGSLLFALVSSVVAWALIRNLPGLLEVLVLSRLNLRQGASYAIT 883
Cdd:PRK11281 800 YWVWSDLITVFSYLDSITLWHYTTTTAGGAVVESITLGNLLFALIILVVTYVLVRNLPGLLEVLVLSRLNLRQGTSYAIT 879
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 884 TILNYVIIIVGAMTVFGSLGVSWDKLQWLAAALSVGLGFGLQEIFGNFVSGLIILFERPVRIGDTVTIGTFSGTVSKIRI 963
Cdd:PRK11281 880 TLLTYIIIAVGAVTAFSTLGVSWDKLQWLVAALSVGLGFGLQEIFANFVSGLIILFERPVRIGDTVTIGTFSGTVSKIRI 959
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 964 RATTITDFDRKEVIIPNKAFVTERLINWSLSDTTTRVVIRLGVAYGSDLDKVKEVLLKAAKSHPKVMHEPAPDVFFTTFG 1043
Cdd:PRK11281 960 RATTITDFDRKEVIVPNKAFVTERLINWSLSDTVTRVVIKVGVAYGSDLEKVRELLLQAATENPRVMKEPEPQVFFLNFG 1039
|
1050 1060 1070 1080 1090 1100 1110
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 578272093 1044 PSTLDHELRLYVRELRDRSYTVDELNRTIDRLCRENNINIAFNQLEVHLRNEKGDEHTEVKREIQGDDPTPA 1115
Cdd:PRK11281 1040 ASTLDHELRLYVRELGDRSPTVDELNRRIDRLFRENDINIAFNQLDVFLKNQKGDEVVEVKRDLKGDDPTPA 1111
|
|
| MscK |
COG3264 |
Small-conductance mechanosensitive channel MscK [Cell wall/membrane/envelope biogenesis]; |
837-1097 |
2.58e-110 |
|
Small-conductance mechanosensitive channel MscK [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442495 [Multi-domain] Cd Length: 281 Bit Score: 344.88 E-value: 2.58e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 837 SVTMGSLLFALVSSVVAWALIRNLPGLLEVLVLSRLNLRQGASYAITTILNYVIIIVGAMTVFGSLGVSWDKLQWLAAAL 916
Cdd:COG3264 17 SISLPNLLLALLILVVTYLLARLLSRLLERRLLRRTRLDPGLRYLISKLIRYLIIVLGLLIALSALGIDLTALAALAGAL 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 917 SVGLGFGLQEIFGNFVSGLIILFERPVRIGDTVTIGTFSGTVSKIRIRATTITDFDRKEVIIPNKAFVTERLINWSLSDT 996
Cdd:COG3264 97 GVGIGFGLQDIVSNFISGLILLFERPFRVGDWIEIGGTEGTVEEIGLRSTRIRTFDGEEVIIPNSELITNPVINWSLSDP 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 997 TTRVVIRLGVAYGSDLDKVKEVLLKAAKSHPKVMHEPAPDVFFTTFGPSTLDHELRLYVRELRDRSYTVDELNRTIDRLC 1076
Cdd:COG3264 177 RRRVEIPVGVAYGSDLEKVRELLLEAAREHPRVLKDPAPSVLFTEFGDSSVNFELRFWVNDPRDRLRVRSDLNEAIKKAF 256
|
250 260
....*....|....*....|.
gi 578272093 1077 RENNINIAFNQLEVHLRNEKG 1097
Cdd:COG3264 257 REEGIEIPFPQRDVHLRNPPG 277
|
|
| PRK10929 |
PRK10929 |
putative mechanosensitive channel protein; Provisional |
9-1098 |
3.43e-104 |
|
putative mechanosensitive channel protein; Provisional
Pssm-ID: 236798 [Multi-domain] Cd Length: 1109 Bit Score: 353.59 E-value: 3.43e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 9 HPVLVFLLATLFFFATAPlswaradnnNDIPSRSDVQSQLDTLNKQKDLSALDklVQQDLTETLETLDKIERVKAETTQL 88
Cdd:PRK10929 2 RLIITFLMAWLLSWGAYA---------ATAPDEKQITQELEQAKAAKTPAQAE--IVEALQSALNWLEERKGSLERAKQY 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 89 RQKVAQAPENMRKATESLNALSDvdnddETRKTLATLSLRQLESRV----AQLLDDLQTAQS------DLGTYNSQLVSL 158
Cdd:PRK10929 71 QQVIDNFPKLSAELRQQLNNERD-----EPRSVPPNMSTDALEQEIlqvsSQLLEKSRQAQQeqdrarEISDSLSQLPQQ 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 159 QTQpervqnamyaASQQLQQIRNRLNGTSVGEGTLRPTQQTLLLVQQALLNAQIEQ-QRKSLEGNT------VLQDTLQK 231
Cdd:PRK10929 146 QTE----------ARRQLNEIERRLQTLGTPNTPLAQAQLTALQAESAALKALVDElELAQLSANNrqelarLRSELAKK 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 232 QRDyvtaninRLEHQLQLLQEAVNSKR-------LTLTEKTAQEA--VSPDETARIQANPLVKQELeaNHQlSQRLIVAT 302
Cdd:PRK10929 216 RSQ-------QLDAYLQALRNQLNSQRqreaeraLESTELLAEQSgdLPKSIVAQFKINRELSQAL--NQQ-AQRMDLIA 285
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 303 ESGNSLVQQNIRVKnwldralQAERNIKEQIAVLKGSLLLSRILYQQQQTLPSADELEDMTNRIADLRLEQFDVNQQRDA 382
Cdd:PRK10929 286 SQQRQAASQTLQVR-------QALNTLREQSQWLGVSNALGEALRAQVARLPEMPKPQQLDTEMAQLRVQRLRYEDLLNK 358
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 383 LFQSDTFVAKLEEGHSSEVNpEVHDALLQVvdmRRELLDQLNKQLGNQLMMAINLQINQQQLVSVSKSLQEILTQQIFWV 462
Cdd:PRK10929 359 QPQLRQIRQADGQPLTAEQN-RILDAQLRT---QRELLNSLLSGGDTLILELTKLKVANSQLEDALKEVNEATHRYLFWV 434
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 463 NSNKPMDWDWIKSFPETLKaQIKSMKITVNWEKAWPAVMIAFLAGLPLLLIAGLIRWRLGWLKKYQDKL---ASEVGQLR 539
Cdd:PRK10929 435 ADVSPISLSYPLEIAQDLR-RLLSLDTFSQLGKASVMMLTSKETLLPLFGALLLVGFSISSRRHYHAFLersSSRVGKVT 513
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 540 NDSQLHTPKAILIDLIRALPVCLIILAVGLIL-----LTMQLNISDllwAFSKKLALFWlVFGVCWKVLEKDGVAVRHFN 614
Cdd:PRK10929 514 QDHFSLTLRTVFWSILVASPLPVLWAALGYGLqnawpYPLAVAIGD---GVTATVPLLW-VFMICATFARPNGLFIAHFG 589
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 615 mpaqltshWRRQIVRVSLALLPLHFWSVVAELSPLHLMDDV--------MGQLVILLNLLLIAILMWPMCRDS---WRDK 683
Cdd:PRK10929 590 --------WPRERVARAMRYYLLSIGLIVPLIMALITFDNLndrefsgtLGRLCFILLCGALSLVTLSLKRAGiplYLDK 661
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 684 ESHN---IRLATVTVLAIIPLALMVLTATGYFYTTLRLSGRwIETVylVIVWNLL---YQTVLRGL-----SVAARRIAY 752
Cdd:PRK10929 662 EGSGdniINHALWNLLIGAPLVAALASALGYLATAQALLAR-LETS--VAIWFLLlvvYHIIRRWMliqrrRIAFDRAKQ 738
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 753 RRAIARRQHQVKE-------GAEGAEPQEEPTIALEQVNQQTLRI--TMLVMIALFAVMFwaIWSDLITVFAYLDSITLW 823
Cdd:PRK10929 739 RRAEILAQRARGEeeahhssSPEGAIEVEEPVIDLDAISAQSLRLvrSILTLIALLSVIV--LWSEIHSAFGFLENISLW 816
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 824 QYNGTEAGAAVMKSVTMGSLLFALVSSVVAWALIRNLPGLLEVLVLSRLNLRQGASYAITTILNYVIIIVGAMTVFGSLG 903
Cdd:PRK10929 817 DVTSTVQGVESLQPITLGSVLIAILVFIITTQLVRNLPALLELALLQHLDLTPGTGYAITTITKYLLMLIGGLVGFSMIG 896
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 904 VSWDKLQWLAAALSVGLGFGLQEIFGNFVSGLIILFERPVRIGDTVTIGTFSGTVSKIRIRATTITDFDRKEVIIPNKAF 983
Cdd:PRK10929 897 IEWSKLQWLVAALGVGLGFGLQEIFANFISGLIILFEKPIRIGDTVTIRDLTGSVTKINTRATTISDWDRKEIIVPNKAF 976
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 984 VTERLINWSLSDTTTRVVIRLGVAYGSDLDKVKEVLLKAAKSHPKVMHEPAPDVFFTTFGPSTLDHELRLYVRELRDRSY 1063
Cdd:PRK10929 977 ITEQFINWSLSDSVTRVVLTIPAPADANSEEVTEILLTAARRCSLVLDNPAPEVFLVDLQQGIQIFELRIYAAEMGHRMP 1056
|
1130 1140 1150
....*....|....*....|....*....|....*
gi 578272093 1064 TVDELNRTIDRLCRENNINIAFNQLEVHLRNEKGD 1098
Cdd:PRK10929 1057 LRHEIHQLILAGFREHGIDMPFPPFQMRLESLGGK 1091
|
|
| MscS_TM |
pfam12794 |
Mechanosensitive ion channel inner membrane domain 1; The small mechanosensitive channel, MscS, ... |
508-822 |
4.81e-87 |
|
Mechanosensitive ion channel inner membrane domain 1; The small mechanosensitive channel, MscS, is a part of the turgor-driven solute efflux system that protects bacteria from lysis in the event of osmotic shock. The MscS protein alone is sufficient to form a functional mechanosensitive channel gated directly by tension in the lipid bilayer. The MscS proteins are heptamers of three transmembrane subunits with seven converging M3 domains, and this domain is one of the inner membrane domains.
Pssm-ID: 432789 [Multi-domain] Cd Length: 332 Bit Score: 284.49 E-value: 4.81e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 508 LPLLLIAGLIRWRLGWLKKYQDKLASEVGQLRNDSQLHTPKAILIDLIRALPVCLIILAVGLILLTM--QLNISDLLWAF 585
Cdd:pfam12794 1 LLLLLVAGLLLWLRRRLKRRLERLAERVGKVTQDSFLHTLRALLLTLLLALPLPLLLAALGWLLQLSgwATPFSVALGAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 586 SKKLALFWLVFGVCWKVLEKDGVAVRHFNMPAQLTSHWRRQIVRVSLALLPLHFWSVVAELSPLHLMDDVMGQLVILLNL 665
Cdd:pfam12794 81 LLALALALLVFEFFRRLLRPDGLAIRHFGWPEERVQRLRRQLRWLIWVLVPLVFVLGLAEALPDSLARDVLGRLAFIILM 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 666 LLIAILMWPMCRDSWRDKESHN-------IRLATVTVLAIIPLALMVLTATGYFYTTLRLSGRWIETVYLVIVWNLLYQT 738
Cdd:pfam12794 161 LLLAVFLWRLLRPGRGLYASHLgegpnsrLRRLWWPLLVLAPLALAVLALLGYYYTALQLLGRLIDSLYLLLGWLLVYAL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 739 VLRGLSVA----ARRIAYRRAIARRQHQVKEGAEGAEP----QEEPTIALEQVNQQTLRITMLVMIALFAVMFWAIWSDL 810
Cdd:pfam12794 241 ALRWLLVArrrlAYRRAKERRAEALAQRAKEGEEGAEPsessVEEPELDLETISAQSLRLLRLLLLLAFLVGLYWIWSDL 320
|
330
....*....|..
gi 578272093 811 ITVFAYLDSITL 822
Cdd:pfam12794 321 LPAFSYLDNITL 332
|
|
| MS_channel |
pfam00924 |
Mechanosensitive ion channel; Two members of this protein family: Swiss:Q57634 and Swiss: ... |
883-1082 |
1.19e-66 |
|
Mechanosensitive ion channel; Two members of this protein family: Swiss:Q57634 and Swiss:Q58543 of M. jannaschii have been functionally characterized. Both proteins form mechanosensitive (MS) ion channels upon reconstitution into liposomes and functional examination by the patch-clamp technique. Therefore this family are likely to also be MS channel proteins.
Pssm-ID: 459999 [Multi-domain] Cd Length: 203 Bit Score: 222.86 E-value: 1.19e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 883 TTILNYVIIIVGAMTVFGSLGVSWDKLQWLAAALSVGLGFGLQEIFGNFVSGLIILFERPVRIGDTVTIGTFSGTVSKIR 962
Cdd:pfam00924 1 KKILKYLIIVVGILIVLSYLGVNVSALLAGLGALGLALGFALQDLVSNLVSGIIILFEKPFKIGDWIEIGDIEGTVEDIG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 963 IRATTITDFDRKEVIIPNKAFVTERLINWSLSDtTTRVVIRLGVAYGSD---LDKVKEVLLKAAKSHPKVMHEPAPDVFF 1039
Cdd:pfam00924 81 LRTTTIRTFDGRLVTIPNSSILTSNIINYSRSP-TRRVELSIGVAYSSDpdkLEKVIEILKEAAYEHPLVLKDPEPPVVF 159
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 578272093 1040 TTFGPSTLDHELRLYVREL-RDRSYTVDELNRTIDRLCRENNIN 1082
Cdd:pfam00924 160 GEFGDSSLNFELRVWVKTLpGEYFNVRSELNLRIKKALEENGIE 203
|
|
| MscS_porin |
pfam12795 |
Mechanosensitive ion channel porin domain; The small mechanosensitive channel, MscS, is a part ... |
47-286 |
3.34e-65 |
|
Mechanosensitive ion channel porin domain; The small mechanosensitive channel, MscS, is a part of the turgor-driven solute efflux system that protects bacteria from lysis in the event of osmotic shock. The MscS protein alone is sufficient to form a functional mechanosensitive channel gated directly by tension in the lipid bilayer. The MscS proteins are heptamers of three transmembrane subunits with seven converging M3 domains, and this MscS_porin is towards the N-terminal of the molecules. The high concentration of negative charges at the extracellular entrance of the pore helps select the cations for efflux.
Pssm-ID: 432790 [Multi-domain] Cd Length: 238 Bit Score: 220.25 E-value: 3.34e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 47 QLDTLNKQKDLSALDKLVQQDLTETLETLDKIERVKAETTQLRQKVAQAPENMRKATESLNALSDvDNDDETRKTLATLS 126
Cdd:pfam12795 1 KLDELEKAKLDEAAKKKLLQDLQQALSLLDKIDASKQRAAAYQKALDDAPAELRELRQELAALQA-KAEAAPKEILASLS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 127 LRQLESRVAQLLDDLQTAQSDLGTYNSQLVSLQTQPERVQNAMYAASQQLQQIRNRLNGTSVGEGTLRPTQQTLLLVQQA 206
Cdd:pfam12795 80 LEELEQRLLQTSAQLQELQNQLAQLNSQLIELQTRPERAQQQLSEARQRLQQIRNRLNGPAPPGEPLSEAQRWALQAELA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 207 LLNAQIEQQRKSLEGNTVLQDTLQKQRDYVTANINRLEHQLQLLQEAVNSKRLTLTEKtAQEAVSPDETARIQANPLVKQ 286
Cdd:pfam12795 160 ALKAQIDMLEQELLSNNNRQDLLKARRDLLTLRIQRLEQQLQALQELLNEKRLQEAEQ-AVAQTEQLAEEAAGDHPLVQQ 238
|
|
| MscS |
COG0668 |
Small-conductance mechanosensitive channel [Cell wall/membrane/envelope biogenesis]; |
822-1096 |
2.69e-53 |
|
Small-conductance mechanosensitive channel [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440432 [Multi-domain] Cd Length: 276 Bit Score: 187.78 E-value: 2.69e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 822 LWQYNGTEAGAAVMKSVTMGSLLFALVSSVVAWALIRNLPGLLEVLVLSRLNLRQGASYaITTILNYVIIIVGAMTVFGS 901
Cdd:COG0668 6 LWSLLGLLLLLGELLLALLPKLLLALLILLIGWLLIRLLRRLIRRLLRRARRDRTLLPL-LRNILKILIVIIAILLILSI 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 902 LGVSwdkLQWLAAALSVG---LGFGLQEIFGNFVSGLIILFERPVRIGDTVTIGTFSGTVSKIRIRATTITDFDRKEVII 978
Cdd:COG0668 85 LGVN---ITSLLAGLGAAglaIGLAAQDLLSNFIAGIFILLERPFRVGDWIEVGGVEGTVEEIGLRSTRLRTLDGRLVTI 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 979 PNKAFVTERLINWSlSDTTTRVVIRLGVAYGSDLDKVKEVLLKAAKSHPKVMHEPApDVFFTTFGPSTLDHELRLYVREl 1058
Cdd:COG0668 162 PNSKILSSPITNYS-RGPTRRVDVTIGVDYDTDIDKARELLKEILEELPRILKDPA-VVGVTELGDSSVNLRVRAWTKP- 238
|
250 260 270
....*....|....*....|....*....|....*...
gi 578272093 1059 RDRSYTVDELNRTIDRLCRENNINIAFNQLEVHLRNEK 1096
Cdd:COG0668 239 GDYWDVRRDIRERIKAALDEAGIEIPFPTRTVHLAEEA 276
|
|
| PRK10334 |
PRK10334 |
small-conductance mechanosensitive channel MscS; |
882-1099 |
2.48e-19 |
|
small-conductance mechanosensitive channel MscS;
Pssm-ID: 182386 [Multi-domain] Cd Length: 286 Bit Score: 89.59 E-value: 2.48e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 882 ITTILNYVIIIVGAMTVFGSLGVSWDKLQWLAAALSVGLGFGLQEIFGNFVSGLIILFERPVRIGDTVTIGTFSGTVSKI 961
Cdd:PRK10334 69 LSALVRYGIIAFTLIAALGRVGVQTASVIAVLGAAGLAVGLALQGSLSNLAAGVLLVMFRPFRAGEYVDLGGVAGTVLSV 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 962 RIRATTITDFDRKEVIIPNKAFVTERLINWSlSDTTTRVVIRLGVAYGSDLDKVKEVLLKAAKSHPKVMHEPAPDVFFTT 1041
Cdd:PRK10334 149 QIFSTTMRTADGKIIVIPNGKIIAGNIINFS-REPVRRNEFIIGVAYDSDIDQVKQILTNIIQSEDRILKDREMTVRLNE 227
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 578272093 1042 FGPSTLDHELRLYVRELRDRSYTVDELNRtIDRLCRENNINIAFNQLEVHLRNEKGDE 1099
Cdd:PRK10334 228 LGASSINFVVRVWSNSGDLQNVYWDVLER-IKREFDAAGISFPYPQMDVNFKRVKEDK 284
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
52-402 |
3.30e-12 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 69.55 E-value: 3.30e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 52 NKQKDLSALDKLVQQ--DLTETLETL-DKIERVKAETTQLRQKVAQAPENMRKATESLNALSDVDNDDETRKTLATLSLR 128
Cdd:COG4372 32 QLRKALFELDKLQEEleQLREELEQArEELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAE 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 129 QLESRVAQllddLQTAQSDLGTYNSQlvsLQTQPERVQNAMYAASQQLQQIRNRLNGTsvgEGTLRPTQQTLLLVQQALL 208
Cdd:COG4372 112 ELQEELEE----LQKERQDLEQQRKQ---LEAQIAELQSEIAEREEELKELEEQLESL---QEELAALEQELQALSEAEA 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 209 NAQIEQQRKSLEGNTVLQDTLQKQRdyvtaninRLEHQLQLLQEAVNSKRLTLTEKTAQEAVSPDETARIQANPLVKQEL 288
Cdd:COG4372 182 EQALDELLKEANRNAEKEEELAEAE--------KLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLE 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 289 EANHQLSQRLIVATESGNSLVQQNIRVKNWLDRALQAERNIKEQIAVLKGSLLLSRILYQQQQTLPSADELEDMTNRIAD 368
Cdd:COG4372 254 EVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALA 333
|
330 340 350
....*....|....*....|....*....|....
gi 578272093 369 LRLEQFDVNQQRDALFQSDTFVAKLEEGHSSEVN 402
Cdd:COG4372 334 ILLAELADLLQLLLVGLLDNDVLELLSKGAEAGV 367
|
|
| GimC |
COG1382 |
Prefoldin, chaperonin cofactor [Posttranslational modification, protein turnover, chaperones]; |
64-187 |
1.22e-11 |
|
Prefoldin, chaperonin cofactor [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440992 [Multi-domain] Cd Length: 121 Bit Score: 62.60 E-value: 1.22e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 64 VQQDLT-ETLETLDKIERVKAETTQLRQKVAQAPENMRKATESLNALSDVDNDDETRKTLATLSLRQLESRVAQLLDDlq 142
Cdd:COG1382 1 MMQNLPpEVQNQLAQLQQLQQQLQAVAAQKQQVESELKEAEKALEELEKLPDDAEVYKSVGNLLVKTDKEEVIKELEE-- 78
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 578272093 143 taqsDLGTYNSQLVSLQTQPERVQNAMYAASQQLQQIRNRLNGTS 187
Cdd:COG1382 79 ----KKETLELRLKTLEKQEERLQKQLEELQEKLQEALSGAGGGG 119
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
76-281 |
4.88e-09 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 59.78 E-value: 4.88e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 76 DKIERVKAETTQLRQKVAQAPENMRKATESLNALSDVDNDDETRKTLATLSLRQLESRVAQLLDDLQTAQSDLGTYNSQL 155
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 156 VSLQTQPERVQNAMYAASQQlQQIRNRLNGTSVGEGTLRptQQTLLLVQQAlLNAQIEQQRKSLEGNTVLQDTLQKQRDY 235
Cdd:COG4942 100 EAQKEELAELLRALYRLGRQ-PPLALLLSPEDFLDAVRR--LQYLKYLAPA-RREQAEELRADLAELAALRAELEAERAE 175
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 578272093 236 VTANINRLEHQLQLLQEAVNSKRLTLTEKTAQEAVSPDETARIQAN 281
Cdd:COG4942 176 LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQE 221
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
36-356 |
5.33e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 60.72 E-value: 5.33e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 36 NDIpsRSDVQSQLDTLNKQ-------KDLSALDKLVQQDLT--ETLETLDKIERVKAETTQLRQKVAQAPENMRKATESL 106
Cdd:COG1196 192 EDI--LGELERQLEPLERQaekaeryRELKEELKELEAELLllKLRELEAELEELEAELEELEAELEELEAELAELEAEL 269
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 107 NALSDVDNDDETRKTLATLSLRQLESRVAQLLDDLQTAQSDLGTYNSQLVSLQTQPERVQNAMYAASQQLQQIRNRLNgt 186
Cdd:COG1196 270 EELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELE-- 347
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 187 svgegTLRPTQQTLLLVQQALLNAQIEQQRKSLEGNTVLQDTLQKQRDYVTANINRLEHQLQLLQEAVNSKRLTLTEKTA 266
Cdd:COG1196 348 -----EAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEE 422
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 267 QEAvspDETARIQANPLVKQELEANHQLSQRLIVATESGNSLVQQNIRVKNWLDRALQAERNIKEQIAVLKGSLLLSRIL 346
Cdd:COG1196 423 LEE---LEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEA 499
|
330
....*....|
gi 578272093 347 YQQQQTLPSA 356
Cdd:COG1196 500 EADYEGFLEG 509
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
17-282 |
9.33e-09 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 58.69 E-value: 9.33e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 17 ATLFFFATAPLSWARADNNNDIPSRSDVQSQLDTLNKQkdLSALDKLVQQDLTETLETLDKIERVKAETTQLRQKVAQAP 96
Cdd:COG3883 1 ALALALAAPTPAFADPQIQAKQKELSELQAELEAAQAE--LDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 97 ENMRKATESL-NALSDVDNDDETRKTLATLslrqLESR-VAQLLDDLQtAQSDLGTYNSQLV-SLQTQPERVQNAMYAAS 173
Cdd:COG3883 79 AEIEERREELgERARALYRSGGSVSYLDVL----LGSEsFSDFLDRLS-ALSKIADADADLLeELKADKAELEAKKAELE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 174 QQLQQIRnrlngtsvgegtlrpTQQTLLLVQQALLNAQIEQQRKSLEGNTVLQDTLQKQRDYVTANINRLEHQLQLLQEA 253
Cdd:COG3883 154 AKLAELE---------------ALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAA 218
|
250 260
....*....|....*....|....*....
gi 578272093 254 VNSKRLTLTEKTAQEAVSPDETARIQANP 282
Cdd:COG3883 219 AAAAAAAAAAAAAAAAAAAAAAAAAASAA 247
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
44-325 |
3.20e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 58.14 E-value: 3.20e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 44 VQSQLDTLNKQKdlSALDKLVQQDLTETLETLDKIERVKAETTQLRQKVAQAPENMRKATESLNALSDVDNDDETRKTLA 123
Cdd:TIGR02168 265 LEEKLEELRLEV--SELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAEL 342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 124 TLSLRQLESRVAQLLDDLQTAQSDLGTYNSQLVSLQTQPERVQNAMYAASQQLQQIRNRLNGTSVG----EGTLRPTQQT 199
Cdd:TIGR02168 343 EEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARlerlEDRRERLQQE 422
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 200 LLLVQQALLNAQIEQQRKSLEGNTVLQDTLQKQRDYVTANINRLEHQLQLLQEAVNSKRLTLTEKTAQEAVSPDETARIQ 279
Cdd:TIGR02168 423 IEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLE 502
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 578272093 280 ANPL-VKQELEANHQLSQRLivatesgnSLVQQNIRVKNWLDRALQA 325
Cdd:TIGR02168 503 GFSEgVKALLKNQSGLSGIL--------GVLSELISVDEGYEAAIEA 541
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
41-263 |
3.99e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 57.76 E-value: 3.99e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 41 RSDVQSQLDTLNKQ-----KDLSALDKLVQQdLTETLETLDK-IERVKAETTQLRQKVAQAPENMRKATESLNALSDVDN 114
Cdd:TIGR02168 714 LEQLRKELEELSRQisalrKDLARLEAEVEQ-LEERIAQLSKeLTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIE 792
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 115 DDETRKTLATLSLRQLESRVAQLLDDLQTAQSDLGTYNSQLVSLQTQPERVQNAMYAASQQLQQIRNRLNGTSVGEGTLR 194
Cdd:TIGR02168 793 QLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELE 872
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 578272093 195 pTQQTLLLVQQALLNAQIEQQRKSLEgntvlqdTLQKQRDYVTANINRLEHQLQLLQEAVNSKRLTLTE 263
Cdd:TIGR02168 873 -SELEALLNERASLEEALALLRSELE-------ELSEELRELESKRSELRRELEELREKLAQLELRLEG 933
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
44-541 |
4.26e-08 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 57.82 E-value: 4.26e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 44 VQSQLDTLnKQKDLSALDKLVQQDLtetletlDKIERV----KAETTQLRQKVAQApenmRKATESLNA-LSDVDNDDET 118
Cdd:pfam15921 243 VEDQLEAL-KSESQNKIELLLQQHQ-------DRIEQLisehEVEITGLTEKASSA----RSQANSIQSqLEIIQEQARN 310
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 119 RKTLATLSLRQLESRVAQLLDDLQTAQSdlgTYNSQLVSLQTQpervqnaMYAASQQLQQIRNRLNGTSVGEGTLRPTQQ 198
Cdd:pfam15921 311 QNSMYMRQLSDLESTVSQLRSELREAKR---MYEDKIEELEKQ-------LVLANSELTEARTERDQFSQESGNLDDQLQ 380
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 199 TLLL---VQQALLNAQIEQQRKSLE---GNTVLQDTLQKQRDYVTANINRLEHQLQLLqeavnskrltlteKTAQEAVSP 272
Cdd:pfam15921 381 KLLAdlhKREKELSLEKEQNKRLWDrdtGNSITIDHLRRELDDRNMEVQRLEALLKAM-------------KSECQGQME 447
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 273 DETARIQANplvKQELEANHQLSQRLIVATESGNSLVQQNIRVKNWLDralQAERNIKEqiavlkgsllLSRILYQQQQT 352
Cdd:pfam15921 448 RQMAAIQGK---NESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLE---SSERTVSD----------LTASLQEKERA 511
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 353 LPSAD-ELEDMTNRIaDLRLEQFdvnQQrdalfqsdtfvAKLEEGHSSEVNPEVHDALLQ------VVDMRRELLDQLNK 425
Cdd:pfam15921 512 IEATNaEITKLRSRV-DLKLQEL---QH-----------LKNEGDHLRNVQTECEALKLQmaekdkVIEILRQQIENMTQ 576
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 426 QLGNQLMMAINLQINQQQLVsvskslQEIltqqifwvnSNKPMDWDWIKSFPETLKAQIKSMKITVN---WEKAwpavmi 502
Cdd:pfam15921 577 LVGQHGRTAGAMQVEKAQLE------KEI---------NDRRLELQEFKILKDKKDAKIRELEARVSdleLEKV------ 635
|
490 500 510 520
....*....|....*....|....*....|....*....|
gi 578272093 503 aflaglpLLLIAGLIRWR-LGWLKKYQDKLASEVGQLRND 541
Cdd:pfam15921 636 -------KLVNAGSERLRaVKDIKQERDQLLNEVKTSRNE 668
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
76-340 |
1.07e-07 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 56.46 E-value: 1.07e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 76 DKIERVKAETTQLRQKVAQAPENMRKATESLNALSDVDNDDETRKTL--ATLSLRQLESRVAQL---LDDLQTAQSDLGT 150
Cdd:COG4913 610 AKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYswDEIDVASAEREIAELeaeLERLDASSDDLAA 689
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 151 YNSQLVSLQTQPERVQNAMYAASQQLQQIRNRLNGTSVGEGTLRPTQQTLLLVQQALLNAQIEQQRKSLEGNTV---LQD 227
Cdd:COG4913 690 LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVereLRE 769
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 228 TLQKQRDYVTANINRLEHQLQLLQEAVNSKrltLTEKTAQEAVSPDETARIQAnplVKQELEAN--HQLSQRLIvatesg 305
Cdd:COG4913 770 NLEERIDALRARLNRAEEELERAMRAFNRE---WPAETADLDADLESLPEYLA---LLDRLEEDglPEYEERFK------ 837
|
250 260 270
....*....|....*....|....*....|....*.
gi 578272093 306 NSLVQQNIRVKNWLDRAL-QAERNIKEQIAVLKGSL 340
Cdd:COG4913 838 ELLNENSIEFVADLLSKLrRAIREIKERIDPLNDSL 873
|
|
| PRK11465 |
PRK11465 |
putative mechanosensitive channel protein; Provisional |
820-1024 |
2.85e-07 |
|
putative mechanosensitive channel protein; Provisional
Pssm-ID: 183147 [Multi-domain] Cd Length: 741 Bit Score: 54.79 E-value: 2.85e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 820 ITLWQYNGTEAGAAVMKSVTMGSLLfaLVSSVVAWALirnLPGLLEVLVLSRLNLRQGASYAITTILNY-------VIII 892
Cdd:PRK11465 449 FDFWNWLQNGAGEKTVDILIRIALI--LFFSAVGWTV---LASLIENRLASDIHGRPLPSARTRTLLTLfrnalavIIST 523
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 893 VGAMTVFGSLGVSWDKLQWLAAALSVGLGFGLQEIFGNFVSGLIILFERPVRIGDTVTIGTFSGTVSKIRIRATTITDFD 972
Cdd:PRK11465 524 ITIMIVLSEIGVNIAPLLAGAGALGLAISFGSQTLVKDIITGVFIQFENGMNTGDLVTIGPLTGTVERMSIRSVGVRQDT 603
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 973 RKEVIIPnkafvterlinWSlSDTT--------TRVVIRLGVAYGSDLDKVKEVLLKAAK 1024
Cdd:PRK11465 604 GAYHIIP-----------WS-SITTfanfvrgiGSVVANYDVDRHEDADKANQALKDAVA 651
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
126-456 |
3.46e-07 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 53.75 E-value: 3.46e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 126 SLRQLESRVAQLLDDLQTAQSDLGTYNSQLVSLQTQPERVQNAMYAASQQLQQIRNRLNgtsVGEGTLRPTQQTLLLVQQ 205
Cdd:COG4372 32 QLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQ---AAQAELAQAQEELESLQE 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 206 AL---------LNAQIEQQRKSLEGNTVLQDTLQKQRDYVTANINRLEHQLQLLQEAVNSKRLTLTEKTAQEAVSPDETA 276
Cdd:COG4372 109 EAeelqeeleeLQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDEL 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 277 RIQANPLVKQELEANHQLSQRLIVATESGNSLVQQNIRVKNWLDRALQAERNIKEQIAVLKGSLLLSRILYQQQQTLPSA 356
Cdd:COG4372 189 LKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAIL 268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 357 DELEDMTNRIADLRLEQFDVNQQRDALFQSDTFVAKLEEGHSSEVNPEVHDALLQVVDMRRELLDQLNKQLGNQLMMAIN 436
Cdd:COG4372 269 VEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLLLV 348
|
330 340
....*....|....*....|
gi 578272093 437 LQINQQQLVSVSKSLQEILT 456
Cdd:COG4372 349 GLLDNDVLELLSKGAEAGVA 368
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
41-424 |
4.35e-07 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 54.28 E-value: 4.35e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 41 RSDVQSQLDTLNKQKDLSA--LDKLvQQDLTETLETLDKIERVKAETTQLRQKVAQAP----------ENMRKATESL-- 106
Cdd:PRK02224 215 LAELDEEIERYEEQREQARetRDEA-DEVLEEHEERREELETLEAEIEDLRETIAETErereelaeevRDLRERLEELee 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 107 ---NALSDVDNDDETRKTLAtLSLRQLESRVAQLLDDLQTAQSDLGTYNSQLVS-------LQTQPERVQNAMYAASQQL 176
Cdd:PRK02224 294 erdDLLAEAGLDDADAEAVE-ARREELEDRDEELRDRLEECRVAAQAHNEEAESlredaddLEERAEELREEAAELESEL 372
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 177 QQIRNRLNgtsvgegtlrpTQQTlllvQQALLNAQIEQQRKSLEGNTV-------LQDTLQKQRDYVTANINRLEHQLQL 249
Cdd:PRK02224 373 EEAREAVE-----------DRRE----EIEELEEEIEELRERFGDAPVdlgnaedFLEELREERDELREREAELEATLRT 437
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 250 LQEAVNSKRLTLTEKTAQE-----AVSPD----ETARIQANPLVKQ--ELEANHQ-LSQRLivatESGNSLVQQNIRVKN 317
Cdd:PRK02224 438 ARERVEEAEALLEAGKCPEcgqpvEGSPHvetiEEDRERVEELEAEleDLEEEVEeVEERL----ERAEDLVEAEDRIER 513
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 318 WLDRALQAERNIKEQIAVLKGSLLLSRILYQQQQTLPSA------------DELEDMTNRIADLRLEQFDVNQQRDALFQ 385
Cdd:PRK02224 514 LEERREDLEELIAERRETIEEKRERAEELRERAAELEAEaeekreaaaeaeEEAEEAREEVAELNSKLAELKERIESLER 593
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 578272093 386 SDTFVAKLEE-GHSSEVNPEVHDALLQVVDMRRELLDQLN 424
Cdd:PRK02224 594 IRTLLAAIADaEDEIERLREKREALAELNDERRERLAEKR 633
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
42-340 |
1.07e-06 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 53.26 E-value: 1.07e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 42 SDVQSQLDTLNKQKD--------LSALDKLVQQDLTETL-----------ETLDKIERVKAETTQLRQKVAQAPENMRKA 102
Cdd:pfam01576 780 KELEAQIDAANKGREeavkqlkkLQAQMKDLQRELEEARasrdeilaqskESEKKLKNLEAELLQLQEDLAASERARRQA 859
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 103 TESLNALSDVDNDDETRKTLATLSLRQLESRVAQLLDDLQTAQSdlgtyNSQLVSlqtqpERVQNamyaASQQLQQIRNR 182
Cdd:pfam01576 860 QQERDELADEIASGASGKSALQDEKRRLEARIAQLEEELEEEQS-----NTELLN-----DRLRK----STLQVEQLTTE 925
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 183 LNGTsvgegtlRPTQQTLLLVQQallnaQIEQQRKSLEgnTVLQDTLQKQRDYVTANINRLEHQL-----QLLQEA---- 253
Cdd:pfam01576 926 LAAE-------RSTSQKSESARQ-----QLERQNKELK--AKLQEMEGTVKSKFKSSIAALEAKIaqleeQLEQESrerq 991
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 254 VNSKRLTLTEKTAQEAVSPDETARIQANPLVKQELEAN---HQLSQRLIVATESGNSLVQQNIRVKNWLDRALQAERNIK 330
Cdd:pfam01576 992 AANKLVRRTEKKLKEVLLQVEDERRHADQYKDQAEKGNsrmKQLKRQLEEAEEEASRANAARRKLQRELDDATESNESMN 1071
|
330
....*....|
gi 578272093 331 EQIAVLKGSL 340
Cdd:pfam01576 1072 REVSTLKSKL 1081
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
65-369 |
1.82e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 52.37 E-value: 1.82e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 65 QQDLTETLETLDKIERVKAET-TQL----RQ-KVAQAPENMRKATESLNALSDVDNDDETRKTLATL--SLRQLESRVAQ 136
Cdd:TIGR02168 178 ERKLERTRENLDRLEDILNELeRQLksleRQaEKAERYKELKAELRELELALLVLRLEELREELEELqeELKEAEEELEE 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 137 LLDDLQTAQSDLGTYNSQLVSLQTQPERVQNAMYAAS-------QQLQQIRNRL----NGTSVGEGTLRPTQQTLLLVQQ 205
Cdd:TIGR02168 258 LTAELQELEEKLEELRLEVSELEEEIEELQKELYALAneisrleQQKQILRERLanleRQLEELEAQLEELESKLDELAE 337
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 206 AL--LNAQIEQQRKSLEG--------NTVLQD------TLQKQRDYVTANINRLEHQLQLLQEAV--NSKRLTLTEKTAQ 267
Cdd:TIGR02168 338 ELaeLEEKLEELKEELESleaeleelEAELEElesrleELEEQLETLRSKVAQLELQIASLNNEIerLEARLERLEDRRE 417
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 268 EAVSPDETARIQANPLVKQELEANHQLSQRLIV-ATESGNSLVQQNIRVKNWLDRALQAERNIKEQIAVLKGSLLLSRIL 346
Cdd:TIGR02168 418 RLQQEIEELLKKLEEAELKELQAELEELEEELEeLQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERL 497
|
330 340 350
....*....|....*....|....*....|.
gi 578272093 347 YQQQQTLP--------SADELEDMTNRIADL 369
Cdd:TIGR02168 498 QENLEGFSegvkallkNQSGLSGILGVLSEL 528
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
129-459 |
2.38e-06 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 52.15 E-value: 2.38e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 129 QLESRVAQLLDDLQTAQSDLGTYNSQLVSLQTQPERVQNAMYAASQQLQQIRNRLngtsvgegtlrptQQtlLLVQQALL 208
Cdd:pfam12128 601 ELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDL-------------RR--LFDEKQSE 665
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 209 NAQIEQQRKSlegntvLQDTLQKQRDYVTANINRLEHQLQLLQEAVNSKRLTLTEKTaQEAVSPDETARIQANPLVKQEL 288
Cdd:pfam12128 666 KDKKNKALAE------RKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEK-QAYWQVVEGALDAQLALLKAAI 738
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 289 EANHQLSQRLIVA--TESGNSLVQQNIRVKNWLDRALQAERNIK--EQIAVlKGSLLLSRILYQQQQTLPSADELEdmtN 364
Cdd:pfam12128 739 AARRSGAKAELKAleTWYKRDLASLGVDPDVIAKLKREIRTLERkiERIAV-RRQEVLRYFDWYQETWLQRRPRLA---T 814
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 365 RIADLRLEQFDVNQQRDALFQS-DTFVAKLE-EGHSSEVNPEVHDALLQVVDMRRELLDQLNK-QLGNQLMMAINLQINQ 441
Cdd:pfam12128 815 QLSNIERAISELQQQLARLIADtKLRRAKLEmERKASEKQQVRLSENLRGLRCEMSKLATLKEdANSEQAQGSIGERLAQ 894
|
330
....*....|....*....
gi 578272093 442 -QQLVSVSKSLQEILTQQI 459
Cdd:pfam12128 895 lEDLKLKRDYLSESVKKYV 913
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
130-361 |
1.69e-05 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 48.36 E-value: 1.69e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 130 LESRVAQLLDDLQTAQSDLGTYNSQLVSLQTQPERVQNAMYAASQQLQQIRNRLNGTsvgEGTLRPTQQTLLLVQQALln 209
Cdd:COG4372 29 LSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEEL---NEQLQAAQAELAQAQEEL-- 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 210 AQIEQQRKSLEGNtvlQDTLQKQRDYVTANINRLEHQLQLLQEAVNSKRLTLTEKTAQEAVSPDETARIQANPLVKQELE 289
Cdd:COG4372 104 ESLQEEAEELQEE---LEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAE 180
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 578272093 290 ANHQLSQrlIVATESGNSLVQQNIRVKNWLDRALQAERNIKEQIAVLKGSLLLSRILYQQQQTLPSADELED 361
Cdd:COG4372 181 AEQALDE--LLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEE 250
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
196-458 |
1.70e-05 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 49.16 E-value: 1.70e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 196 TQQTLLLVQQALLNAQIEQQRKSLEGNTVLQDTLQKQRDYVTANINRLEHQLQLLQE-----AVNSKRLTLTEKTAQEAV 270
Cdd:COG1196 253 AELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEErrrelEERLEELEEELAELEEEL 332
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 271 SPDETARIQANPLVKQELEANHQLSQRLIVATESGNSLVQQNIRVKNWLDRALQAERNIKEQIAVLKgslllSRILYQQQ 350
Cdd:COG1196 333 EELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELA-----AQLEELEE 407
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 351 QTLPSADELEDMTNRIADLRLEQFDVNQQRDALFQSDTFVAKLEEGHSSEvnpevHDALLQVVDMRRELLDQLNKQLgnq 430
Cdd:COG1196 408 AEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEE-----EEALLELLAELLEEAALLEAAL--- 479
|
250 260
....*....|....*....|....*...
gi 578272093 431 lmmaINLQINQQQLVSVSKSLQEILTQQ 458
Cdd:COG1196 480 ----AELLEELAEAAARLLLLLEAEADY 503
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
55-298 |
1.76e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 49.14 E-value: 1.76e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 55 KDLSALDKLVQQDLTETLETLDKIERVKAETTQLRqkvaQAPENMRKATESLNALSDVDNDDETRKTLATlSLRQLESRV 134
Cdd:COG4913 204 KPIGDLDDFVREYMLEEPDTFEAADALVEHFDDLE----RAHEALEDAREQIELLEPIRELAERYAAARE-RLAELEYLR 278
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 135 AQLldDLQTAQSDLGTYNSQLVSLQTQPERVQNAMYAASQQLQQIRNRLNGtsvgegtlrptqqtlllVQQALLNA---Q 211
Cdd:COG4913 279 AAL--RLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDE-----------------LEAQIRGNggdR 339
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 212 IEQQRKSLEGNTVLQDTLQKQRDYVTANINRLEHQLQLLQEAVNSKRLTLTE--KTAQEAVSPDETARIQANPLVKQELE 289
Cdd:COG4913 340 LEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAAllEALEEELEALEEALAEAEAALRDLRR 419
|
....*....
gi 578272093 290 ANHQLSQRL 298
Cdd:COG4913 420 ELRELEAEI 428
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
12-381 |
3.69e-05 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 48.09 E-value: 3.69e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 12 LVFLLATLFFFATAPLSWARADN--NNDIPSRSDVQSQLDTL-----NKQKDLSALDKLVQQDLTETLETLDKIERVKAE 84
Cdd:TIGR04523 4 LISLLAAISVFTATGFSYVGYKNiaNKQDTEEKQLEKKLKTIknelkNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQ 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 85 TTQLRQKVAQAPENMRKATESLNAL-SDVDNDDETRKTLATLS------LRQLESRVAQLLDDLQTAQSDLGTYNSQLVS 157
Cdd:TIGR04523 84 IKDLNDKLKKNKDKINKLNSDLSKInSEIKNDKEQKNKLEVELnklekqKKENKKNIDKFLTEIKKKEKELEKLNNKYND 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 158 LQTQPERVQNAMYAASQQLQQIRNRLNGTsvgEGTLRPTQQTLLLVQ-----QALLNAQI---EQQRKSLEGNTvlqDTL 229
Cdd:TIGR04523 164 LKKQKEELENELNLLEKEKLNIQKNIDKI---KNKLLKLELLLSNLKkkiqkNKSLESQIselKKQNNQLKDNI---EKK 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 230 QKQRDYVTANINRLEHQL-QLLQEAVNSKRlTLTEKTAQEavspdETARIQANPLVKQ------ELEA-NHQLSQRLIVA 301
Cdd:TIGR04523 238 QQEINEKTTEISNTQTQLnQLKDEQNKIKK-QLSEKQKEL-----EQNNKKIKELEKQlnqlksEISDlNNQKEQDWNKE 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 302 TESGNSLVQQNIR-VKNWLDRALQAERNIKEQIAVLKGSL-------------------LLSRILYQQQQTLpsaDELED 361
Cdd:TIGR04523 312 LKSELKNQEKKLEeIQNQISQNNKIISQLNEQISQLKKELtnsesensekqreleekqnEIEKLKKENQSYK---QEIKN 388
|
410 420
....*....|....*....|...
gi 578272093 362 MTNRIADLRLE---QFDVNQQRD 381
Cdd:TIGR04523 389 LESQINDLESKiqnQEKLNQQKD 411
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
30-389 |
5.82e-05 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 47.26 E-value: 5.82e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 30 ARADNNNDIPSRSDVQSQLDTLNKQKDlsaldKLVQQDLTETLEtldKIERVKAETTQLRQKVAQAPENMRKATE----- 104
Cdd:COG5185 237 GFQDPESELEDLAQTSDKLEKLVEQNT-----DLRLEKLGENAE---SSKRLNENANNLIKQFENTKEKIAEYTKsidik 308
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 105 -SLNALSDVDNDDETRKTLA------TLSLRQLESRVAQLLDDLQTAQSDLGTYNSQLVSLQTQPERvqnamyaaSQQLQ 177
Cdd:COG5185 309 kATESLEEQLAAAEAEQELEeskretETGIQNLTAEIEQGQESLTENLEAIKEEIENIVGEVELSKS--------SEELD 380
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 178 QIrnrlngtsvgegtlrptQQTLLLVQQALLNAQIEQQRKSLEGNTVLQDTlqkqrdyvtanINRLEHQLQLLQEAVNSK 257
Cdd:COG5185 381 SF-----------------KDTIESTKESLDEIPQNQRGYAQEILATLEDT-----------LKAADRQIEELQRQIEQA 432
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 258 RLTLTEKTAQEAVSPDEtariqanpLVKQELEANHQLSQRLIVATESGNSLVQQNIRVknwLDRALQAernIKEQIAVLK 337
Cdd:COG5185 433 TSSNEEVSKLLNELISE--------LNKVMREADEESQSRLEEAYDEINRSVRSKKED---LNEELTQ---IESRVSTLK 498
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 578272093 338 GSLLLSRILYQQQ-----QTLPSADELEDMTNRIADLRLEQFDVNQQRDALFQSDTF 389
Cdd:COG5185 499 ATLEKLRAKLERQlegvrSKLDQVAESLKDFMRARGYAHILALENLIPASELIQASN 555
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
204-458 |
7.75e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 46.30 E-value: 7.75e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 204 QQALLNAQIEQQRKSLEGNTVLQDTLQKQRDYVTANINRLEHQLQLLQEAVNSKRLTLTEKTAQEAVspdetariqanpL 283
Cdd:COG4942 28 ELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE------------L 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 284 VKQELEANHQLSQRLIVATESGnslvqQNIRVKNWL--DRALQAERNIKeqiavlkgslLLSRILYQQQQtlpSADELED 361
Cdd:COG4942 96 RAELEAQKEELAELLRALYRLG-----RQPPLALLLspEDFLDAVRRLQ----------YLKYLAPARRE---QAEELRA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 362 MTNRIADLRLEQfdvNQQRDALfqsDTFVAKLEEghssevnpeVHDALLQVVDMRRELLDQLNKQLGNQLMMAINLQINQ 441
Cdd:COG4942 158 DLAELAALRAEL---EAERAEL---EALLAELEE---------ERAALEALKAERQKLLARLEKELAELAAELAELQQEA 222
|
250
....*....|....*..
gi 578272093 442 QQLVSVSKSLQEILTQQ 458
Cdd:COG4942 223 EELEALIARLEAEAAAA 239
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
57-430 |
8.14e-05 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 46.89 E-value: 8.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 57 LSALDKLVQQDLTETLETLDKIERVKAETTQLRQKVAQAPENMRKATESLNALSDVDNddetRKTLATLSLRQLESRVAQ 136
Cdd:TIGR00618 523 PGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDN----RSKEDIPNLQNITVRLQD 598
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 137 LLDDLQTAQ-SDLGTYNSQLVSLQtqperVQNAMYAASQQLQQIRNRLngtSVGEGTLRPTQQTLLLVQQALLNAQI-EQ 214
Cdd:TIGR00618 599 LTEKLSEAEdMLACEQHALLRKLQ-----PEQDLQDVRLHLQQCSQEL---ALKLTALHALQLTLTQERVREHALSIrVL 670
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 215 QRKSLEGNTVLQDTLQKQRDYVTANINRLEHQLQLLQEAVNSKRLTLTEKTAQEAVSPDETARIQANPLVKQEL------ 288
Cdd:TIGR00618 671 PKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSlkelmh 750
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 289 ----------EANHQLSQRLIVATESGNSLVQ--QNIRVKNWLDRALQA-----ERNIKEQIAVLKGSLLLSRILYQQ-- 349
Cdd:TIGR00618 751 qartvlkartEAHFNNNEEVTAALQTGAELSHlaAEIQFFNRLREEDTHllktlEAEIGQEIPSDEDILNLQCETLVQee 830
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 350 QQTLPSADELEDMTNRIADLRLEQFDVNQQRDALFQSDTFVAKLEE---GHSSEVNPEVHDALLQVVdmrRELLDQLNKQ 426
Cdd:TIGR00618 831 EQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDklnGINQIKIQFDGDALIKFL---HEITLYANVR 907
|
....
gi 578272093 427 LGNQ 430
Cdd:TIGR00618 908 LANQ 911
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
10-255 |
1.69e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 45.53 E-value: 1.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 10 PVLVFLLATLFFFATAPLSWARADNNNDIPS--RSDVQSQLDTLNKQKDLSALDKLVQQDLTETLETLDKIERVKAETTQ 87
Cdd:COG4717 276 AGVLFLVLGLLALLFLLLAREKASLGKEAEElqALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLRE 355
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 88 LRQKVAQAP-ENMRKATESLNALSDVDNDDETRKTLATLS-LRQLESRVAQLLDDLQTAQSDLGTYNSQL--VSLQTQPE 163
Cdd:COG4717 356 AEELEEELQlEELEQEIAALLAEAGVEDEEELRAALEQAEeYQELKEELEELEEQLEELLGELEELLEALdeEELEEELE 435
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 164 RVQNAMYAASQQLQQIRNRLngtsvgegtlrptqqtlllvqqallnAQIEQQRKSLEGNTVLQDTLQkQRDYVTANINRL 243
Cdd:COG4717 436 ELEEELEELEEELEELREEL--------------------------AELEAELEQLEEDGELAELLQ-ELEELKAELREL 488
|
250
....*....|....*
gi 578272093 244 EHQ---LQLLQEAVN 255
Cdd:COG4717 489 AEEwaaLKLALELLE 503
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
40-334 |
2.27e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 45.44 E-value: 2.27e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 40 SRSDVQSQLDTLnkQKDLSALDKLVQQ------DLTETLETLD-KIERVKAETTQLRQKVAQAPENMRKATESLNALSDV 112
Cdd:TIGR02169 710 ELSDASRKIGEI--EKEIEQLEQEEEKlkerleELEEDLSSLEqEIENVKSELKELEARIEELEEDLHKLEEALNDLEAR 787
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 113 DNDDETRKTLAtlSLRQLESRVAQLLDDLQTAQSDLGTYNSQLVSLQTQPERVQNAMYAASQQLQQIRNRLNgtsVGEGT 192
Cdd:TIGR02169 788 LSHSRIPEIQA--ELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIE---NLNGK 862
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 193 LRPTQQTLllvqqALLNAQIEQQRKSLEGntvlqdtLQKQRDYVTANINRLEHQLQLLQEAVNSKRLTLTEKTAQEAVSP 272
Cdd:TIGR02169 863 KEELEEEL-----EELEAALRDLESRLGD-------LKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALE 930
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 273 DETARIQANPLVKQE----------LEANHQLSQRLIVATESGNSL-VQQNIRVKNWLD-----RA-LQAERN-IKEQIA 334
Cdd:TIGR02169 931 EELSEIEDPKGEDEEipeeelsledVQAELQRVEEEIRALEPVNMLaIQEYEEVLKRLDelkekRAkLEEERKaILERIE 1010
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
60-426 |
5.50e-04 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 44.40 E-value: 5.50e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 60 LDKLVQQDLTETLETLDKIERVKAETTQLRQKVAqapenmRKATESLNALSDVDnDDETRKTLATLSLRQLESRVAQLLD 139
Cdd:pfam01576 206 LEKAKRKLEGESTDLQEQIAELQAQIAELRAQLA------KKEEELQAALARLE-EETAQKNNALKKIRELEAQISELQE 278
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 140 DLQTAQS----------DLGtynSQLVSLQTQPERVQNAMyAASQQLQQIRNR----LNGTsVGEGTLRPTQQTLLLVQ- 204
Cdd:pfam01576 279 DLESERAarnkaekqrrDLG---EELEALKTELEDTLDTT-AAQQELRSKREQevteLKKA-LEEETRSHEAQLQEMRQk 353
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 205 --QAL--LNAQIEQQRK----------SLEG-NTVLQ---DTLQKQRDYVTANINRLEHQLQLLQeavnsKRLTLTEKTA 266
Cdd:pfam01576 354 htQALeeLTEQLEQAKRnkanlekakqALESeNAELQaelRTLQQAKQDSEHKRKKLEGQLQELQ-----ARLSESERQR 428
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 267 QEAVspDETARIQ---------------------------------ANPLVKQELEANHQLSQRLIVATESGNSLVQQni 313
Cdd:pfam01576 429 AELA--EKLSKLQselesvssllneaegkniklskdvsslesqlqdTQELLQEETRQKLNLSTRLRQLEDERNSLQEQ-- 504
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 314 rvknwLDRALQAERNIKEQIAVLKGSLLLSRilYQQQQTLPSADELEDMTNRIadlrleQFDVNQQRDALFQSDTFVAKL 393
Cdd:pfam01576 505 -----LEEEEEAKRNVERQLSTLQAQLSDMK--KKLEEDAGTLEALEEGKKRL------QRELEALTQQLEEKAAAYDKL 571
|
410 420 430
....*....|....*....|....*....|...
gi 578272093 394 EEGhSSEVNPEVHDALLQvVDMRRELLDQLNKQ 426
Cdd:pfam01576 572 EKT-KNRLQQELDDLLVD-LDHQRQLVSNLEKK 602
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
122-342 |
1.19e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 42.44 E-value: 1.19e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 122 LATLSLRQLESRVAQLLDDLQTAQSDLGTYNSQLVSLQTQPERVQNAMYAASQQLQQIRNRLNGTsvgEGTLRPTQQTL- 200
Cdd:COG4942 10 LLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRAL---EQELAALEAELa 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 201 -LLVQQALLNAQIEQQRKSLEGNTV--------------------------------LQDTLQKQRDYVTANINRLEHQL 247
Cdd:COG4942 87 eLEKEIAELRAELEAQKEELAELLRalyrlgrqpplalllspedfldavrrlqylkyLAPARREQAEELRADLAELAALR 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 248 QLLQEAVNSKRLTLTE-KTAQEAVSPDETARIQANPLVKQELEANHQLSQRLIVATESGNSLVQQNIRvknwlDRALQAE 326
Cdd:COG4942 167 AELEAERAELEALLAElEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEA-----EAAAAAE 241
|
250
....*....|....*.
gi 578272093 327 RNIKEQIAVLKGSLLL 342
Cdd:COG4942 242 RTPAAGFAALKGKLPW 257
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
60-253 |
1.85e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 42.31 E-value: 1.85e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 60 LDKLVQQDLTETLETLDKIErvkAETTQLRQKVAQAPENMRKATESlNALSDVDNddetRKTLATLSLRQLESRVAQLLD 139
Cdd:COG3206 162 LEQNLELRREEARKALEFLE---EQLPELRKELEEAEAALEEFRQK-NGLVDLSE----EAKLLLQQLSELESQLAEARA 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 140 DLQTAQSDLGTYNSQLVS-LQTQPERVQNAMYAA-SQQLQQIRNRLNGTSVGEGTLRPTQQTLLLvQQALLNAQIEQQ-R 216
Cdd:COG3206 234 ELAEAEARLAALRAQLGSgPDALPELLQSPVIQQlRAQLAELEAELAELSARYTPNHPDVIALRA-QIAALRAQLQQEaQ 312
|
170 180 190
....*....|....*....|....*....|....*..
gi 578272093 217 KSLEGNTVLQDTLQKQRDYVTANINRLEHQLQLLQEA 253
Cdd:COG3206 313 RILASLEAELEALQAREASLQAQLAQLEARLAELPEL 349
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
32-340 |
4.10e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 41.57 E-value: 4.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 32 ADNNNDIpsrSDVQSQLDTLNKQ----KDLSALDKLVQQDLTETLETLDKIERVKAET---------TQLRQKVAQAPEN 98
Cdd:TIGR00606 761 QRLKNDI---EEQETLLGTIMPEeesaKVCLTDVTIMERFQMELKDVERKIAQQAAKLqgsdldrtvQQVNQEKQEKQHE 837
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 99 MRKATESLNALSDVDNDDETRKTLATLSLRQLESRVAQLLDDLQTAQSdlgtYNSQLVSLQTQPERVQNAMYAASQQLQQ 178
Cdd:TIGR00606 838 LDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQ----FEEQLVELSTEVQSLIREIKDAKEQDSP 913
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 179 IRNRLNGTSVGEGTLRPTQQTLLLVQQALLN------AQIEQQRKSLEgnTVLQDTLQKQRDYVTANINRLEHQL----- 247
Cdd:TIGR00606 914 LETFLEKDQQEKEELISSKETSNKKAQDKVNdikekvKNIHGYMKDIE--NKIQDGKDDYLKQKETELNTVNAQLeecek 991
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 248 --QLLQEAVNSKRLTLTEKTAQEAVSPDE-TARIQANPL--VKQELEA-NHQLSQRLIVATESGNSLVQQNIR-VKNWLD 320
Cdd:TIGR00606 992 hqEKINEDMRLMRQDIDTQKIQERWLQDNlTLRKRENELkeVEEELKQhLKEMGQMQVLQMKQEHQKLEENIDlIKRNHV 1071
|
330 340
....*....|....*....|
gi 578272093 321 RALQAERNIKEQIAVLKGSL 340
Cdd:TIGR00606 1072 LALGRQKGYEKEIKHFKKEL 1091
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
41-395 |
4.36e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 41.29 E-value: 4.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 41 RSDVQSQLDTLNKQKDLSALDKLVQQ---DLTETLETLDKIERVKAETTQLRQKVAQAPENMRKATESLNALSDvDNDDE 117
Cdd:COG4717 111 LEELREELEKLEKLLQLLPLYQELEAleaELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLE-QLSLA 189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 118 TRKTLATL--SLRQLESRVAQLLDDLQTAQSDLGTYNSQLVSLQTQPERvqnamYAASQQLQQIRNRLNGTSV------- 188
Cdd:COG4717 190 TEEELQDLaeELEELQQRLAELEEELEEAQEELEELEEELEQLENELEA-----AALEERLKEARLLLLIAAAllallgl 264
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 189 ---GEGTLRPTQQTLLLVQQALLNAQIEQQRKSLEGNTVLQDT--LQKQRDYVTANINRLEHQLQLLQEAVNSKRLTLTE 263
Cdd:COG4717 265 ggsLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELqaLPALEELEEEELEELLAALGLPPDLSPEELLELLD 344
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 264 --KTAQEAVSPDETARIQAnpLVKQELEANHQLSQRLIVATESG-NSLVQQNIRVKNWLDRALQAERNIKEQIAVLKGSL 340
Cdd:COG4717 345 riEELQELLREAEELEEEL--QLEELEQEIAALLAEAGVEDEEElRAALEQAEEYQELKEELEELEEQLEELLGELEELL 422
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 578272093 341 --LLSRILYQQQQTLpsADELEDMTNRIADLRLEQFDVNQQRDALFQSDTFVAKLEE 395
Cdd:COG4717 423 eaLDEEELEEELEEL--EEELEELEEELEELREELAELEAELEQLEEDGELAELLQE 477
|
|
| CusB_dom_1 |
pfam00529 |
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli ... |
126-249 |
4.45e-03 |
|
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli can be divided into four different domains, the first three domains of the protein are mostly beta-strands and the fourth forms an all alpha-helical domain. This entry represents the first beta-domain (domain 1) of CusB and it is formed by the N and C-terminal ends of the polypeptide (residues 89-102 and 324-385). CusB is part of the copper-transporting efflux system CusCFBA. This domain can also be found in other membrane-fusion proteins, such as HlyD, MdtN, MdtE and AaeA. HlyD is a component of the prototypical alpha-haemolysin (HlyA) bacterial type I secretion system, along with the other components HlyB and TolC. HlyD is anchored in the cytoplasmic membrane by a single transmembrane domain and has a large periplasmic domain within the carboxy-terminal 100 amino acids, HlyB and HlyD form a stable complex that binds the recombinant protein bearing a C-terminal HlyA signal sequence and ATP in the cytoplasm. HlyD, HlyB and TolC combine to form the three-component ABC transporter complex that forms a trans-membrane channel or pore through which HlyA can be transferred directly to the extracellular medium. Cutinase has been shown to be transported effectively through this pore.
Pssm-ID: 425733 [Multi-domain] Cd Length: 322 Bit Score: 40.48 E-value: 4.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 126 SLRQLESRVAQL---LDDLQTAQSDLGTYNSQLVSLQTQPERVQNAMYAASQQLQQIRNRLNGTSVgegtLRP------- 195
Cdd:pfam00529 66 QLAKAQAQVARLqaeLDRLQALESELAISRQDYDGATAQLRAAQAAVKAAQAQLAQAQIDLARRRV----LAPiggisre 141
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 578272093 196 ---TQQTLLLVQQALLNAQIEQQRKSLEGNTVLQDTLQKQRDY----VTANINRLEHQLQL 249
Cdd:pfam00529 142 slvTAGALVAQAQANLLATVAQLDQIYVQITQSAAENQAEVRSelsgAQLQIAEAEAELKL 202
|
|
| TagG |
COG1682 |
ABC-type polysaccharide/teichoic acid/polyol phosphate export permease [Carbohydrate transport ... |
790-924 |
4.63e-03 |
|
ABC-type polysaccharide/teichoic acid/polyol phosphate export permease [Carbohydrate transport and metabolism];
Pssm-ID: 441288 [Multi-domain] Cd Length: 258 Bit Score: 40.17 E-value: 4.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 790 ITMLVMIALFAVMFWAIWSDLITVFAYLD----SITLWQYngteagaaVMKSVTMGSllfalvSSVVAWA-LIRNLPGLL 864
Cdd:COG1682 37 LNPLLMLLVYTFVFGVLLRAPSGGVPYALfllaGLLPWNF--------FSEALNRGS------GSIVANAgLIKKVYFPR 102
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 578272093 865 EVLVLSRLnLRQGASYAITtilnyVIIIVGAMTVFGsLGVSWDKLQWLAAALSV---GLGFGL 924
Cdd:COG1682 103 EILPLARV-LSALVNFLIS-----LVVLLVVLLLFG-VPPSWTLLLLPLALLLLllfGLGLGL 158
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
43-184 |
4.70e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 41.20 E-value: 4.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 43 DVQSQLDTLNKQKD-LSALDKLVQQDLTETLETLDKIERVKAET----TQLRQKVAQAPENMRKATESLNALSDVDNDDE 117
Cdd:TIGR02168 793 QLKEELKALREALDeLRAELTLLNEEAANLRERLESLERRIAATerrlEDLEEQIEELSEDIESLAAEIEELEELIEELE 872
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90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 578272093 118 TRKTLATLSLRQLESRVAQLLDDLQTAQSDLGTYNS-------QLVSLQTQPERVQNAMYAASQQLQQIRNRLN 184
Cdd:TIGR02168 873 SELEALLNERASLEEALALLRSELEELSEELRELESkrselrrELEELREKLAQLELRLEGLEVRIDNLQERLS 946
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|
| Surf_Exclu_PgrA |
TIGR04320 |
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface ... |
126-232 |
5.86e-03 |
|
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.
Pssm-ID: 275124 [Multi-domain] Cd Length: 356 Bit Score: 40.48 E-value: 5.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578272093 126 SLRQLESRVAQLLDDLQTAQSDLGTYNSQLVSLQTQPERVQNAMYAASQQLQQIRNRLNGTSvgegtlrptQQTLLLVQQ 205
Cdd:TIGR04320 255 SLAALQAKLATAQADLAAAQTALNTAQAALTSAQTAYAAAQAALATAQKELANAQAQALQTA---------QNNLATAQA 325
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90 100
....*....|....*....|....*....
gi 578272093 206 ALLNAQ--IEQQRKSLEGNTVLQDTLQKQ 232
Cdd:TIGR04320 326 ALANAEarLAKAKEALANLNADLAKKQAA 354
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