|
Name |
Accession |
Description |
Interval |
E-value |
| PstB |
COG1117 |
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
29-283 |
0e+00 |
|
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440734 [Multi-domain] Cd Length: 258 Bit Score: 537.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 29 DTNSHSVIYSTQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELVPSVKTAGKILYRDQDIFDQ 108
Cdd:COG1117 4 PASTLEPKIEVRNLNVYYGDKQALKDINLDIPENKVTALIGPSGCGKSTLLRCLNRMNDLIPGARVEGEILLDGEDIYDP 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 109 KYSKEQLRTNVGMVFQQPNPFPKSIYDNITYGPKIHGIKNKKVLDEIVEKSLRGAAIWDELKDRLHTNAYSLSGGQQQRV 188
Cdd:COG1117 84 DVDVVELRRRVGMVFQKPNPFPKSIYDNVAYGLRLHGIKSKSELDEIVEESLRKAALWDEVKDRLKKSALGLSGGQQQRL 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 189 CIARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEKYTIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSN 268
Cdd:COG1117 164 CIARALAVEPEVLLMDEPTSALDPISTAKIEELILELKKDYTIVIVTHNMQQAARVSDYTAFFYLGELVEFGPTEQIFTN 243
|
250
....*....|....*
gi 580041203 269 PSNKKTEDYISGRFG 283
Cdd:COG1117 244 PKDKRTEDYITGRFG 258
|
|
| 3a0107s01c2 |
TIGR00972 |
phosphate ABC transporter, ATP-binding protein; This model represents the ATP-binding protein ... |
36-282 |
8.91e-178 |
|
phosphate ABC transporter, ATP-binding protein; This model represents the ATP-binding protein of a family of ABC transporters for inorganic phosphate. In the model species Escherichia coli, a constitutive transporter for inorganic phosphate, with low affinity, is also present. The high affinity transporter that includes this polypeptide is induced when extracellular phosphate concentrations are low. The proteins most similar to the members of this family but not included appear to be amino acid transporters. [Transport and binding proteins, Anions]
Pssm-ID: 273372 [Multi-domain] Cd Length: 247 Bit Score: 489.50 E-value: 8.91e-178
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 36 IYSTQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELVPSVKTAGKILYRDQDIFDQKYSKEQL 115
Cdd:TIGR00972 1 AIEIENLNLFYGEKEALKNINLDIPKNQVTALIGPSGCGKSTLLRSLNRMNDLVPGVRIEGKVLFDGQDIYDKKIDVVEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 116 RTNVGMVFQQPNPFPKSIYDNITYGPKIHGIKNKKVLDEIVEKSLRGAAIWDELKDRLHTNAYSLSGGQQQRVCIARCLA 195
Cdd:TIGR00972 81 RRRVGMVFQKPNPFPMSIYDNIAYGPRLHGIKDKKELDEIVEESLKKAALWDEVKDRLHDSALGLSGGQQQRLCIARALA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 196 IEPEVILMDEPTSALDPISTLRVEELVQELKEKYTIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNPSNKKTE 275
Cdd:TIGR00972 161 VEPEVLLLDEPTSALDPIATGKIEELIQELKKKYTIVIVTHNMQQAARISDRTAFFYDGELVEYGPTEQIFTNPKEKRTE 240
|
....*..
gi 580041203 276 DYISGRF 282
Cdd:TIGR00972 241 DYISGRF 247
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
38-265 |
7.46e-143 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 400.40 E-value: 7.46e-143
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 38 STQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELVPSVKTAGKILYRDQDIFDQKYSKEQLRT 117
Cdd:cd03260 2 ELRDLNVYYGDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNDLIPGAPDEGEVLLDGKDIYDLDVDVLELRR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 118 NVGMVFQQPNPFPKSIYDNITYGPKIHGIKNKKVLDEIVEKSLRGAAIWDELKDRLHtnAYSLSGGQQQRVCIARCLAIE 197
Cdd:cd03260 82 RVGMVFQKPNPFPGSIYDNVAYGLRLHGIKLKEELDERVEEALRKAALWDEVKDRLH--ALGLSGGQQQRLCLARALANE 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 580041203 198 PEVILMDEPTSALDPISTLRVEELVQELKEKYTIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKI 265
Cdd:cd03260 160 PEVLLLDEPTSALDPISTAKIEELIAELKKEYTIVIVTHNMQQAARVADRTAFLLNGRLVEFGPTEQI 227
|
|
| PRK14243 |
PRK14243 |
phosphate transporter ATP-binding protein; Provisional |
27-283 |
3.75e-136 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 384.90 E-value: 3.75e-136
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 27 PDDTNSHSVIYSTQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELVPSVKTAGKILYRDQDIF 106
Cdd:PRK14243 1 TSTLNGTETVLRTENLNVYYGSFLAVKNVWLDIPKNQITAFIGPSGCGKSTILRCFNRLNDLIPGFRVEGKVTFHGKNLY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 107 DQKYSKEQLRTNVGMVFQQPNPFPKSIYDNITYGPKIHGIKNKkvLDEIVEKSLRGAAIWDELKDRLHTNAYSLSGGQQQ 186
Cdd:PRK14243 81 APDVDPVEVRRRIGMVFQKPNPFPKSIYDNIAYGARINGYKGD--MDELVERSLRQAALWDEVKDKLKQSGLSLSGGQQQ 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 187 RVCIARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEKYTIIMVTHNMQQAARVSDKTAFF---------LNGYVN 257
Cdd:PRK14243 159 RLCIARAIAVQPEVILMDEPCSALDPISTLRIEELMHELKEQYTIIIVTHNMQQAARVSDMTAFFnveltegggRYGYLV 238
|
250 260
....*....|....*....|....*.
gi 580041203 258 EYDDTDKIFSNPSNKKTEDYISGRFG 283
Cdd:PRK14243 239 EFDRTEKIFNSPQQQATRDYVSGRFG 264
|
|
| PRK14239 |
PRK14239 |
phosphate transporter ATP-binding protein; Provisional |
36-283 |
4.62e-134 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 379.12 E-value: 4.62e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 36 IYSTQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELVPSVKTAGKILYRDQDIFDQKYSKEQL 115
Cdd:PRK14239 5 ILQVSDLSVYYNKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSINRMNDLNPEVTITGSIVYNGHNIYSPRTDTVDL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 116 RTNVGMVFQQPNPFPKSIYDNITYGPKIHGIKNKKVLDEIVEKSLRGAAIWDELKDRLHTNAYSLSGGQQQRVCIARCLA 195
Cdd:PRK14239 85 RKEIGMVFQQPNPFPMSIYENVVYGLRLKGIKDKQVLDEAVEKSLKGASIWDEVKDRLHDSALGLSGGQQQRVCIARVLA 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 196 IEPEVILMDEPTSALDPISTLRVEELVQELKEKYTIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNPSNKKTE 275
Cdd:PRK14239 165 TSPKIILLDEPTSALDPISAGKIEETLLGLKDDYTMLLVTRSMQQASRISDRTGFFLDGDLIEYNDTKQMFMNPKHKETE 244
|
....*...
gi 580041203 276 DYISGRFG 283
Cdd:PRK14239 245 DYISGKFG 252
|
|
| PRK14258 |
PRK14258 |
phosphate ABC transporter ATP-binding protein; Provisional |
40-283 |
2.06e-95 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 281.54 E-value: 2.06e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELVPSVKTAGKILYRDQDIFDQKYSKEQLRTNV 119
Cdd:PRK14258 11 NNLSFYYDTQKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMNELESEVRVEGRVEFFNQNIYERRVNLNRLRRQV 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 120 GMVFQQPNPFPKSIYDNITYGPKIHGIKNKKVLDEIVEKSLRGAAIWDELKDRLHTNAYSLSGGQQQRVCIARCLAIEPE 199
Cdd:PRK14258 91 SMVHPKPNLFPMSVYDNVAYGVKIVGWRPKLEIDDIVESALKDADLWDEIKHKIHKSALDLSGGQQQRLCIARALAVKPK 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 200 VILMDEPTSALDPISTLRVEELVQ--ELKEKYTIIMVTHNMQQAARVSDKTAFFLN-----GYVNEYDDTDKIFSNPSNK 272
Cdd:PRK14258 171 VLLMDEPCFGLDPIASMKVESLIQslRLRSELTMVIVSHNLHQVSRLSDFTAFFKGnenriGQLVEFGLTKKIFNSPHDS 250
|
250
....*....|.
gi 580041203 273 KTEDYISGRFG 283
Cdd:PRK14258 251 RTREYVLSRLG 261
|
|
| PRK14267 |
PRK14267 |
phosphate ABC transporter ATP-binding protein; Provisional |
39-283 |
3.64e-94 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 278.26 E-value: 3.64e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 39 TQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELVPSVKTAGKILYRDQDIFDQKYSKEQLRTN 118
Cdd:PRK14267 7 TVNLRVYYGSNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLLELNEEARVEGEVRLFGRNIYSPDVDPIEVRRE 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 119 VGMVFQQPNPFPK-SIYDNITYGPKIHG-IKNKKVLDEIVEKSLRGAAIWDELKDRLHTNAYSLSGGQQQRVCIARCLAI 196
Cdd:PRK14267 87 VGMVFQYPNPFPHlTIYDNVAIGVKLNGlVKSKKELDERVEWALKKAALWDEVKDRLNDYPSNLSGGQRQRLVIARALAM 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 197 EPEVILMDEPTSALDPISTLRVEELVQELKEKYTIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNPSNKKTED 276
Cdd:PRK14267 167 KPKILLMDEPTANIDPVGTAKIEELLFELKKEYTIVLVTHSPAQAARVSDYVAFLYLGKLIEVGPTRKVFENPEHELTEK 246
|
....*..
gi 580041203 277 YISGRFG 283
Cdd:PRK14267 247 YVTGALG 253
|
|
| PRK14247 |
PRK14247 |
phosphate ABC transporter ATP-binding protein; Provisional |
40-281 |
2.19e-87 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 261.00 E-value: 2.19e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELVPSVKTAGKILYRDQDIFdqKYSKEQLRTNV 119
Cdd:PRK14247 7 RDLKVSFGQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLIELYPEARVSGEVYLDGQDIF--KMDVIELRRRV 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 120 GMVFQQPNPFPK-SIYDNITYGPKIHGI-KNKKVLDEIVEKSLRGAAIWDELKDRLHTNAYSLSGGQQQRVCIARCLAIE 197
Cdd:PRK14247 85 QMVFQIPNPIPNlSIFENVALGLKLNRLvKSKKELQERVRWALEKAQLWDEVKDRLDAPAGKLSGGQQQRLCIARALAFQ 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 198 PEVILMDEPTSALDPISTLRVEELVQELKEKYTIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNPSNKKTEDY 277
Cdd:PRK14247 165 PEVLLADEPTANLDPENTAKIESLFLELKKDMTIVLVTHFPQQAARISDYVAFLYKGQIVEWGPTREVFTNPRHELTEKY 244
|
....
gi 580041203 278 ISGR 281
Cdd:PRK14247 245 VTGR 248
|
|
| GlnQ |
COG1126 |
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ... |
40-279 |
2.91e-81 |
|
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440743 [Multi-domain] Cd Length: 239 Bit Score: 244.90 E-value: 2.91e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELvpsvkTAGKILYRDQDIFDQKYSKEQLRTNV 119
Cdd:COG1126 5 ENLHKSFGDLEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEP-----DSGTITVDGEDLTDSKKDINKLRRKV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 120 GMVFQQPNPFP-KSIYDNITYGPKIHGIKNKKVLDEIVEKSLR--GaaiwdeLKDRLHtnAY--SLSGGQQQRVCIARCL 194
Cdd:COG1126 80 GMVFQQFNLFPhLTVLENVTLAPIKVKKMSKAEAEERAMELLErvG------LADKAD--AYpaQLSGGQQQRVAIARAL 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 195 AIEPEVILMDEPTSALDPISTLRVEELVQEL-KEKYTIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNPSNKK 273
Cdd:COG1126 152 AMEPKVMLFDEPTSALDPELVGEVLDVMRDLaKEGMTMVVVTHEMGFAREVADRVVFMDGGRIVEEGPPEEFFENPQHER 231
|
....*.
gi 580041203 274 TEDYIS 279
Cdd:COG1126 232 TRAFLS 237
|
|
| PRK14246 |
PRK14246 |
phosphate ABC transporter ATP-binding protein; Provisional |
36-281 |
3.25e-79 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 240.33 E-value: 3.25e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 36 IYSTQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELVPS-VKTAGKILYRDQDIFdqKYSKEQ 114
Cdd:PRK14246 10 VFNISRLYLYINDKAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEIYDSkIKVDGKVLYFGKDIF--QIDAIK 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 115 LRTNVGMVFQQPNPFPK-SIYDNITYGPKIHGIKNKKVLDEIVEKSLRGAAIWDELKDRLHTNAYSLSGGQQQRVCIARC 193
Cdd:PRK14246 88 LRKEVGMVFQQPNPFPHlSIYDNIAYPLKSHGIKEKREIKKIVEECLRKVGLWKEVYDRLNSPASQLSGGQQQRLTIARA 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 194 LAIEPEVILMDEPTSALDPISTLRVEELVQELKEKYTIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNPSNKK 273
Cdd:PRK14246 168 LALKPKVLLMDEPTSMIDIVNSQAIEKLITELKNEIAIVIVSHNPQQVARVADYVAFLYNGELVEWGSSNEIFTSPKNEL 247
|
....*...
gi 580041203 274 TEDYISGR 281
Cdd:PRK14246 248 TEKYVIGR 255
|
|
| PRK14271 |
PRK14271 |
phosphate ABC transporter ATP-binding protein; Provisional |
29-283 |
2.61e-70 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 218.43 E-value: 2.61e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 29 DTNSHSVIYSTQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELVPSVKTAGKILYRDQDIFDQ 108
Cdd:PRK14271 14 DVDAAAPAMAAVNLTLGFAGKTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMNDKVSGYRYSGDVLLGGRSIFNY 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 109 KYSKEqLRTNVGMVFQQPNPFPKSIYDNITYGPKIHGIKNKKVLDEIVEKSLRGAAIWDELKDRLHTNAYSLSGGQQQRV 188
Cdd:PRK14271 94 RDVLE-FRRRVGMLFQRPNPFPMSIMDNVLAGVRAHKLVPRKEFRGVAQARLTEVGLWDAVKDRLSDSPFRLSGGQQQLL 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 189 CIARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEKYTIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSN 268
Cdd:PRK14271 173 CLARTLAVNPEVLLLDEPTSALDPTTTEKIEEFIRSLADRLTVIIVTHNLAQAARISDRAALFFDGRLVEEGPTEQLFSS 252
|
250
....*....|....*
gi 580041203 269 PSNKKTEDYISGRFG 283
Cdd:PRK14271 253 PKHAETARYVAGLSG 267
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
38-256 |
1.35e-65 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 203.92 E-value: 1.35e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 38 STQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELvpsvkTAGKILYRDQDIFDQKYSKEQLRT 117
Cdd:cd03262 2 EIKNLHKSFGDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEP-----DSGTIIIDGLKLTDDKKNINELRQ 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 118 NVGMVFQQPNPFP-KSIYDNITYGP-KIHGiKNKKVLDEIVEKSLR--GaaiwdeLKDRLHTNAYSLSGGQQQRVCIARC 193
Cdd:cd03262 77 KVGMVFQQFNLFPhLTVLENITLAPiKVKG-MSKAEAEERALELLEkvG------LADKADAYPAQLSGGQQQRVAIARA 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 580041203 194 LAIEPEVILMDEPTSALDPISTLRVEELVQEL-KEKYTIIMVTHNMQQAARVSDKTAFFLNGYV 256
Cdd:cd03262 150 LAMNPKVMLFDEPTSALDPELVGEVLDVMKDLaEEGMTMVVVTHEMGFAREVADRVIFMDDGRI 213
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
43-269 |
4.54e-64 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 200.64 E-value: 4.54e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 43 DLWY---GENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMveLVPsvkTAGKILYRDQDIfdQKYSKEQLRTNV 119
Cdd:COG1122 5 NLSFsypGGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGL--LKP---TSGEVLVDGKDI--TKKNLRELRRKV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 120 GMVFQqpNP----FPKSIYDNITYGPKIHGIKNKKVlDEIVEKSLRGAAIWDeLKDRlhtNAYSLSGGQQQRVCIARCLA 195
Cdd:COG1122 78 GLVFQ--NPddqlFAPTVEEDVAFGPENLGLPREEI-RERVEEALELVGLEH-LADR---PPHELSGGQKQRVAIAGVLA 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 580041203 196 IEPEVILMDEPTSALDPISTLRVEELVQEL-KEKYTIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNP 269
Cdd:COG1122 151 MEPEVLVLDEPTAGLDPRGRRELLELLKRLnKEGKTVIIVTHDLDLVAELADRVIVLDDGRIVADGTPREVFSDY 225
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
41-254 |
4.76e-64 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 198.95 E-value: 4.76e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 41 NLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILYRDQDIFDQKYSKEQLRTNVG 120
Cdd:cd03229 5 NVSKRYGQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEE-----PDSGSILIDGEDLTDLEDELPPLRRRIG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 121 MVFQQPNPFP-KSIYDNITYGpkihgiknkkvldeivekslrgaaiwdelkdrlhtnaysLSGGQQQRVCIARCLAIEPE 199
Cdd:cd03229 80 MVFQDFALFPhLTVLENIALG---------------------------------------LSGGQQQRVALARALAMDPD 120
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 580041203 200 VILMDEPTSALDPISTLRVEELVQELKEK--YTIIMVTHNMQQAARVSDKTAFFLNG 254
Cdd:cd03229 121 VLLLDEPTSALDPITRREVRALLKSLQAQlgITVVLVTHDLDEAARLADRVVVLRDG 177
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
47-269 |
1.21e-61 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 202.83 E-value: 1.21e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 47 GENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvPsvkTAGKILYRDQDIFDQKY-SKEQLRTNVGMVFQQ 125
Cdd:COG1123 276 GGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLR--P---TSGSILFDGKDLTKLSRrSLRELRRRVQMVFQD 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 126 P----NPFpKSIYDNITYGPKIHGIKNKKVLDEIVEKSLRGAAIWDELKDRLhtnAYSLSGGQQQRVCIARCLAIEPEVI 201
Cdd:COG1123 351 PysslNPR-MTVGDIIAEPLRLHGLLSRAERRERVAELLERVGLPPDLADRY---PHELSGGQRQRVAIARALALEPKLL 426
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 202 LMDEPTSALDPISTLRVEELVQELKEKY--TIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNP 269
Cdd:COG1123 427 ILDEPTSALDVSVQAQILNLLRDLQRELglTYLFISHDLAVVRYIADRVAVMYDGRIVEDGPTEEVFANP 496
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
40-250 |
4.19e-59 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 187.34 E-value: 4.19e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELvpsvkTAGKILYRDQDIFDQKYSkeqlRTNV 119
Cdd:cd03259 4 KGLSKTYGSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERP-----DSGEILIDGRDVTGVPPE----RRNI 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 120 GMVFQQPNPFP-KSIYDNITYGPKIHGIKnKKVLDEIVEKSLRGAAIWDELKDRLHTnaysLSGGQQQRVCIARCLAIEP 198
Cdd:cd03259 75 GMVFQDYALFPhLTVAENIAFGLKLRGVP-KAEIRARVRELLELVGLEGLLNRYPHE----LSGGQQQRVALARALAREP 149
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 580041203 199 EVILMDEPTSALDPIstLRvEELVQELKE-----KYTIIMVTHNMQQAARVSDKTAF 250
Cdd:cd03259 150 SLLLLDEPLSALDAK--LR-EELREELKElqrelGITTIYVTHDQEEALALADRIAV 203
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
40-266 |
9.82e-59 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 187.32 E-value: 9.82e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTlnrMVELVPsvKTAGKILYRDQDIFD-QKYSKEQLRTN 118
Cdd:cd03261 4 RGLTKSFGGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRL---IVGLLR--PDSGEVLIDGEDISGlSEAELYRLRRR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 119 VGMVFQQPNPF-PKSIYDNITYGPKIHGIKNKKVLDEIVEKSLRGAaiwdELKDRLHTNAYSLSGGQQQRVCIARCLAIE 197
Cdd:cd03261 79 MGMLFQSGALFdSLTVFENVAFPLREHTRLSEEEIREIVLEKLEAV----GLRGAEDLYPAELSGGMKKRVALARALALD 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 580041203 198 PEVILMDEPTSALDPISTLRVEELVQELKEKY--TIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIF 266
Cdd:cd03261 155 PELLLYDEPTAGLDPIASGVIDDLIRSLKKELglTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTPEELR 225
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
43-254 |
3.34e-58 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 184.98 E-value: 3.34e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 43 DLWY----GENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILYRDQDIfdQKYSKEQLRTN 118
Cdd:cd03225 4 NLSFsypdGARPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLG-----PTSGEVLVDGKDL--TKLSLKELRRK 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 119 VGMVFQQPNP--FPKSIYDNITYGPKIHGIKNKKVlDEIVEKSLRGAaiwdELKDRLHTNAYSLSGGQQQRVCIARCLAI 196
Cdd:cd03225 77 VGLVFQNPDDqfFGPTVEEEVAFGLENLGLPEEEI-EERVEEALELV----GLEGLRDRSPFTLSGGQKQRVAIAGVLAM 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 580041203 197 EPEVILMDEPTSALDPISTLRVEELVQELKEK-YTIIMVTHNMQQAARVSDKTAFFLNG 254
Cdd:cd03225 152 DPDILLLDEPTAGLDPAGRRELLELLKKLKAEgKTIIIVTHDLDLLLELADRVIVLEDG 210
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
46-278 |
2.36e-57 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 184.04 E-value: 2.36e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 46 YGENH-ALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILYRDQDIFDQkySKEQLRTNVGMVFQ 124
Cdd:cd03295 10 YGGGKkAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIE-----PTSGEIFIDGEDIREQ--DPVELRRKIGYVIQ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 125 QPNPFP-KSIYDNITYGPKIHGIKNKKVLDEIVEK-SLRGAAIwDELKDRLhtnAYSLSGGQQQRVCIARCLAIEPEVIL 202
Cdd:cd03295 83 QIGLFPhMTVEENIALVPKLLKWPKEKIRERADELlALVGLDP-AEFADRY---PHELSGGQQQRVGVARALAADPPLLL 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 580041203 203 MDEPTSALDPISTLRVEELVQELKEKY--TIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNPSNKKTEDYI 278
Cdd:cd03295 159 MDEPFGALDPITRDQLQEEFKRLQQELgkTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPDEILRSPANDFVAEFV 236
|
|
| TauB |
COG1116 |
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ... |
47-247 |
9.29e-57 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 182.98 E-value: 9.29e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 47 GENHALQNINLDIYENQITAIIGPSGCGKSTyiktLNRMVE-LVPSvkTAGKILYRDQDIfdqkyskEQLRTNVGMVFQQ 125
Cdd:COG1116 22 GGVTALDDVSLTVAAGEFVALVGPSGCGKST----LLRLIAgLEKP--TSGEVLVDGKPV-------TGPGPDRGVVFQE 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 126 PNPFP-KSIYDNITYGPKIHGIKnKKVLDEIVEKSLR--GaaiwdeLKDRLHTNAYSLSGGQQQRVCIARCLAIEPEVIL 202
Cdd:COG1116 89 PALLPwLTVLDNVALGLELRGVP-KAERRERARELLElvG------LAGFEDAYPHQLSGGMRQRVAIARALANDPEVLL 161
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 580041203 203 MDEPTSALDPISTLRVEELVQEL--KEKYTIIMVTHNMQQAARVSDK 247
Cdd:COG1116 162 MDEPFGALDALTRERLQDELLRLwqETGKTVLFVTHDVDEAVFLADR 208
|
|
| OpuBA |
COG1125 |
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ... |
47-278 |
1.62e-56 |
|
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440742 [Multi-domain] Cd Length: 306 Bit Score: 183.75 E-value: 1.62e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 47 GENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELvpsvkTAGKILYRDQDIfdQKYSKEQLRTNVGMVFQQP 126
Cdd:COG1125 13 DGTVAVDDLSLTIPAGEFTVLVGPSGCGKTTTLRMINRLIEP-----TSGRILIDGEDI--RDLDPVELRRRIGYVIQQI 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 127 NPFP-KSIYDNITYGPKIHGiKNKKVLDEIVekslrgaaiwDELKDRLHTNA------Y--SLSGGQQQRVCIARCLAIE 197
Cdd:COG1125 86 GLFPhMTVAENIATVPRLLG-WDKERIRARV----------DELLELVGLDPeeyrdrYphELSGGQQQRVGVARALAAD 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 198 PEVILMDEPTSALDPISTLRVEELVQELKEKY--TIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNPSNKKTE 275
Cdd:COG1125 155 PPILLMDEPFGALDPITREQLQDELLRLQRELgkTIVFVTHDIDEALKLGDRIAVMREGRIVQYDTPEEILANPANDFVA 234
|
...
gi 580041203 276 DYI 278
Cdd:COG1125 235 DFV 237
|
|
| FetA |
COG4619 |
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism]; |
38-248 |
1.00e-55 |
|
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443661 [Multi-domain] Cd Length: 209 Bit Score: 178.47 E-value: 1.00e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 38 STQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELvpsvkTAGKILYRDQDIfdQKYSKEQLRT 117
Cdd:COG4619 2 ELEGLSFRVGGKPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPP-----TSGEIYLDGKPL--SAMPPPEWRR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 118 NVGMVFQQPNPFPKSIYDNItygPKIHGIKNKKVLDEIVEKSLRGAAIWDELkdrLHTNAYSLSGGQQQRVCIARCLAIE 197
Cdd:COG4619 75 QVAYVPQEPALWGGTVRDNL---PFPFQLRERKFDRERALELLERLGLPPDI---LDKPVERLSGGERQRLALIRALLLQ 148
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 580041203 198 PEVILMDEPTSALDPISTLRVEELVQELKEKY--TIIMVTHNMQQAARVSDKT 248
Cdd:COG4619 149 PDVLLLDEPTSALDPENTRRVEELLREYLAEEgrAVLWVSHDPEQIERVADRV 201
|
|
| DppF |
COG1124 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
40-271 |
9.66e-55 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440741 [Multi-domain] Cd Length: 248 Bit Score: 177.30 E-value: 9.66e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGE----NHALQNINLDIYENQITAIIGPSGCGKSTYIKTLnrmVELVPsvKTAGKILYRDQDIFdQKYSKEqL 115
Cdd:COG1124 5 RNLSVSYGQggrrVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRAL---AGLER--PWSGEVTFDGRPVT-RRRRKA-F 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 116 RTNVGMVFQQP----NPFpKSIYDNITYGPKIHGIKNKkvlDEIVEKSLRGAAIWDELKDRL-HtnaySLSGGQQQRVCI 190
Cdd:COG1124 78 RRRVQMVFQDPyaslHPR-HTVDRILAEPLRIHGLPDR---EERIAELLEQVGLPPSFLDRYpH----QLSGGQRQRVAI 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 191 ARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEKY--TIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSN 268
Cdd:COG1124 150 ARALILEPELLLLDEPTSALDVSVQAEILNLLKDLREERglTYLFVSHDLAVVAHLCDRVAVMQNGRIVEELTVADLLAG 229
|
...
gi 580041203 269 PSN 271
Cdd:COG1124 230 PKH 232
|
|
| MlaF |
COG1127 |
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ... |
40-256 |
1.04e-54 |
|
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 177.09 E-value: 1.04e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTlnrMVELVPsvKTAGKILYRDQDIFDQKYSK-EQLRTN 118
Cdd:COG1127 9 RNLTKSFGDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKL---IIGLLR--PDSGEILVDGQDITGLSEKElYELRRR 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 119 VGMVFQQPNPF-PKSIYDNITYGPKIHGIKNKKVLDEIV-EK----SLRGAAiwdelkdrlhtNAY--SLSGGQQQRVCI 190
Cdd:COG1127 84 IGMLFQGGALFdSLTVFENVAFPLREHTDLSEAEIRELVlEKlelvGLPGAA-----------DKMpsELSGGMRKRVAL 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 580041203 191 ARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEKY--TIIMVTHNMQQAARVSDKTAFFLNGYV 256
Cdd:COG1127 153 ARALALDPEILLYDEPTAGLDPITSAVIDELIRELRDELglTSVVVTHDLDSAFAIADRVAVLADGKI 220
|
|
| PotA |
COG3842 |
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ... |
40-271 |
1.41e-54 |
|
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 180.29 E-value: 1.41e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTyikTLnRMV---ELVpsvkTAGKILYRDQDIFD---QKyske 113
Cdd:COG3842 9 ENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTT---LL-RMIagfETP----DSGRILLDGRDVTGlppEK---- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 114 qlRtNVGMVFQQPNPFP-KSIYDNITYGPKIHGIkNKKVLDEIVEKSLR--GaaiwdeLKDRLHTNAYSLSGGQQQRVCI 190
Cdd:COG3842 77 --R-NVGMVFQDYALFPhLTVAENVAFGLRMRGV-PKAEIRARVAELLElvG------LEGLADRYPHQLSGGQQQRVAL 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 191 ARCLAIEPEVILMDEPTSALDPisTLRvEELVQELKE-----KYTIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKI 265
Cdd:COG3842 147 ARALAPEPRVLLLDEPLSALDA--KLR-EEMREELRRlqrelGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEI 223
|
....*.
gi 580041203 266 FSNPSN 271
Cdd:COG3842 224 YERPAT 229
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
47-247 |
1.72e-54 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 175.74 E-value: 1.72e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 47 GENHALQNINLDIYENQITAIIGPSGCGKSTyiktLNRMVE-LVPSvkTAGKILYRDQDIfdqkyskEQLRTNVGMVFQQ 125
Cdd:cd03293 15 GAVTALEDISLSVEEGEFVALVGPSGCGKST----LLRIIAgLERP--TSGEVLVDGEPV-------TGPGPDRGYVFQQ 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 126 PNPFP-KSIYDNITYGPKIHGIKNKKvLDEIVEKSLR--GaaiwdeLKDRLHtnAY--SLSGGQQQRVCIARCLAIEPEV 200
Cdd:cd03293 82 DALLPwLTVLDNVALGLELQGVPKAE-ARERAEELLElvG------LSGFEN--AYphQLSGGMRQRVALARALAVDPDV 152
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 580041203 201 ILMDEPTSALDPISTLRVEELVQEL--KEKYTIIMVTHNMQQAARVSDK 247
Cdd:cd03293 153 LLLDEPFSALDALTREQLQEELLDIwrETGKTVLLVTHDIDEAVFLADR 201
|
|
| AbcC |
COG1135 |
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism]; |
34-279 |
4.51e-54 |
|
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 178.35 E-value: 4.51e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 34 SVIYSTQNldlwyGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRmveL-VPsvkTAGKILYRDQDIfdQKYSK 112
Cdd:COG1135 8 SKTFPTKG-----GPVTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINL---LeRP---TSGSVLVDGVDL--TALSE 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 113 EQLRT---NVGMVFQQPNPFP-KSIYDNITYGPKIHGIK----NKKVlDEIVEksLRGaaiwdeLKDRLHtnAY--SLSG 182
Cdd:COG1135 75 RELRAarrKIGMIFQHFNLLSsRTVAENVALPLEIAGVPkaeiRKRV-AELLE--LVG------LSDKAD--AYpsQLSG 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 183 GQQQRVCIARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEKY--TIIMVTHNMQQAARVSDKTAFFLNGYVNEYD 260
Cdd:COG1135 144 GQKQRVGIARALANNPKVLLCDEATSALDPETTRSILDLLKDINRELglTIVLITHEMDVVRRICDRVAVLENGRIVEQG 223
|
250
....*....|....*....
gi 580041203 261 DTDKIFSNPSNKKTEDYIS 279
Cdd:COG1135 224 PVLDVFANPQSELTRRFLP 242
|
|
| ECF_ATPase_2 |
TIGR04521 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
48-269 |
4.68e-54 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275314 [Multi-domain] Cd Length: 277 Bit Score: 176.49 E-value: 4.68e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 48 ENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMveLVPsvkTAGKILYRDQDIF-DQKYSKEQLRTNVGMVFQQP 126
Cdd:TIGR04521 17 EKKALDDVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGL--LKP---TSGTVTIDGRDITaKKKKKLKDLRKKVGLVFQFP 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 127 NP--FPKSIYDNITYGPKIHGIKNKKVlDEIVEKSLRGAAIWDELKDRlhtNAYSLSGGQQQRVCIARCLAIEPEVILMD 204
Cdd:TIGR04521 92 EHqlFEETVYKDIAFGPKNLGLSEEEA-EERVKEALELVGLDEEYLER---SPFELSGGQMRRVAIAGVLAMEPEVLILD 167
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 580041203 205 EPTSALDPISTLRVEELVQELKEKY--TIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNP 269
Cdd:TIGR04521 168 EPTAGLDPKGRKEILDLFKRLHKEKglTVILVTHSMEDVAEYADRVIVMHKGKIVLDGTPREVFSDV 234
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
38-247 |
1.77e-53 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 174.46 E-value: 1.77e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 38 STQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRmvELVPSvktAGKILYRDQDIfdQKYSKEQLRT 117
Cdd:COG1120 3 EAENLSVGYGGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAG--LLKPS---SGEVLLDGRDL--ASLSRRELAR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 118 NVGMVFQQPN-PFPKSIYDNITYG--PKIHGIKNKKVLD-EIVEKSLRGAAIWDeLKDRLHTnaySLSGGQQQRVCIARC 193
Cdd:COG1120 76 RIAYVPQEPPaPFGLTVRELVALGryPHLGLFGRPSAEDrEAVEEALERTGLEH-LADRPVD---ELSGGERQRVLIARA 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 580041203 194 LAIEPEVILMDEPTSALDPISTLRVEELVQEL--KEKYTIIMVTHNMQQAARVSDK 247
Cdd:COG1120 152 LAQEPPLLLLDEPTSHLDLAHQLEVLELLRRLarERGRTVVMVLHDLNLAARYADR 207
|
|
| DppD |
COG0444 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
40-269 |
3.70e-53 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 175.63 E-value: 3.70e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWY----GENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvPSVKTAGKILYRDQDIFdqKYSKEQL 115
Cdd:COG0444 5 RNLKVYFptrrGVVKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLP--PPGITSGEILFDGEDLL--KLSEKEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 116 RT----NVGMVFQQP----NPFpKSIYDNITYGPKIHGIKNKKVLDEIVEKSLRGAAIWDElKDRLhtNAYS--LSGGQQ 185
Cdd:COG0444 81 RKirgrEIQMIFQDPmtslNPV-MTVGDQIAEPLRIHGGLSKAEARERAIELLERVGLPDP-ERRL--DRYPheLSGGMR 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 186 QRVCIARCLAIEPEVILMDEPTSALDPisTLRVE--ELVQELKEKY--TIIMVTHNMQQAARVSDKTAFFLNGYVNEYDD 261
Cdd:COG0444 157 QRVMIARALALEPKLLIADEPTTALDV--TIQAQilNLLKDLQRELglAILFITHDLGVVAEIADRVAVMYAGRIVEEGP 234
|
....*...
gi 580041203 262 TDKIFSNP 269
Cdd:COG0444 235 VEELFENP 242
|
|
| LolD |
COG1136 |
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]; |
34-258 |
4.80e-53 |
|
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 172.15 E-value: 4.80e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 34 SVIYSTQNLDLWYG----ENHALQNINLDIYENQITAIIGPSGCGKSTY---IKTLnrmveLVPsvkTAGKILYRDQDIf 106
Cdd:COG1136 2 SPLLELRNLTKSYGtgegEVTALRGVSLSIEAGEFVAIVGPSGSGKSTLlniLGGL-----DRP---TSGEVLIDGQDI- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 107 dQKYSKEQL----RTNVGMVFQQPNPFPK-SIYDNITYGPKIHGIKNKKVLDEIVE--KSLrgaaiwdELKDRLHTNAYS 179
Cdd:COG1136 73 -SSLSERELarlrRRHIGFVFQFFNLLPElTALENVALPLLLAGVSRKERRERAREllERV-------GLGDRLDHRPSQ 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 180 LSGGQQQRVCIARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEKY--TIIMVTHNMQQAARvSDKTAFFLNGYVN 257
Cdd:COG1136 145 LSGGQQQRVAIARALVNRPKLILADEPTGNLDSKTGEEVLELLRELNRELgtTIVMVTHDPELAAR-ADRVIRLRDGRIV 223
|
.
gi 580041203 258 E 258
Cdd:COG1136 224 S 224
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
41-259 |
8.22e-53 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 171.92 E-value: 8.22e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 41 NLDLWY----GENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILYRDQDIfdQKYSKEQL- 115
Cdd:cd03257 6 NLSVSFptggGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLK-----PTSGSIIFDGKDL--LKLSRRLRk 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 116 --RTNVGMVFQQP----NPFpKSIYDNITYGPKIHGIKNKKV-LDEIVEKSLRGAAIWDELKDRLhtnAYSLSGGQQQRV 188
Cdd:cd03257 79 irRKEIQMVFQDPmsslNPR-MTIGEQIAEPLRIHGKLSKKEaRKEAVLLLLVGVGLPEEVLNRY---PHELSGGQRQRV 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 580041203 189 CIARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEKY--TIIMVTHNMQQAARVSDKTAFFLNGYVNEY 259
Cdd:cd03257 155 AIARALALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELglTLLFITHDLGVVAKIADRVAVMYAGKIVEE 227
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
47-270 |
2.25e-51 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 168.14 E-value: 2.25e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 47 GENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNrMVELvPsvkTAGKILYRDQDIFDQkySKEQLRT---NVGMVF 123
Cdd:cd03258 16 GKVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCIN-GLER-P---TSGSVLVDGTDLTLL--SGKELRKarrRIGMIF 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 124 QQPNPF-PKSIYDNITYGPKIHGIKNKkvldEIVEKSLRGAAIWDeLKDRLHtnAY--SLSGGQQQRVCIARCLAIEPEV 200
Cdd:cd03258 89 QHFNLLsSRTVFENVALPLEIAGVPKA----EIEERVLELLELVG-LEDKAD--AYpaQLSGGQKQRVGIARALANNPKV 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 580041203 201 ILMDEPTSALDPISTLRVEELVQELKEKY--TIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNPS 270
Cdd:cd03258 162 LLCDEATSALDPETTQSILALLRDINRELglTIVLITHEMEVVKRICDRVAVMEKGEVVEEGTVEEVFANPQ 233
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
40-256 |
2.70e-51 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 167.67 E-value: 2.70e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGEN----HALQNINLDIYENQITAIIGPSGCGKSTY---IKTLNRmvelvPsvkTAGKILYRDQDIfdQKYSK 112
Cdd:cd03255 4 KNLSKTYGGGgekvQALKGVSLSIEKGEFVAIVGPSGSGKSTLlniLGGLDR-----P---TSGEVRVDGTDI--SKLSE 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 113 EQL----RTNVGMVFQQPNPFPK-SIYDNITYGPKIHGIKnKKVLDEIVEKSLRGAaiwdELKDRLHTNAYSLSGGQQQR 187
Cdd:cd03255 74 KELaafrRRHIGFVFQSFNLLPDlTALENVELPLLLAGVP-KKERRERAEELLERV----GLGDRLNHYPSELSGGQQQR 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 580041203 188 VCIARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEKY--TIIMVTHNMqQAARVSDKTAFFLNGYV 256
Cdd:cd03255 149 VAIARALANDPKIILADEPTGNLDSETGKEVMELLRELNKEAgtTIVVVTHDP-ELAEYADRIIELRDGKI 218
|
|
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
38-254 |
4.63e-51 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 167.55 E-value: 4.63e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 38 STQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILYRDQDIFDQKyskEQLRT 117
Cdd:COG1131 2 EVRGLTKRYGDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLR-----PTSGEVRVLGEDVARDP---AEVRR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 118 NVGMVFQQPNPFPK-SIYDNITYGPKIHGIkNKKVLDEIVEKSLRGAAIWDELKDRLHTnaysLSGGQQQRVCIARCLAI 196
Cdd:COG1131 74 RIGYVPQEPALYPDlTVRENLRFFARLYGL-PRKEARERIDELLELFGLTDAADRKVGT----LSGGMKQRLGLALALLH 148
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 580041203 197 EPEVILMDEPTSALDPISTLRVEELVQELKEK-YTIIMVTHNMQQAARVSDKTAFFLNG 254
Cdd:COG1131 149 DPELLILDEPTSGLDPEARRELWELLRELAAEgKTVLLSTHYLEEAERLCDRVAIIDKG 207
|
|
| proV |
TIGR01186 |
glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine ... |
47-280 |
1.51e-50 |
|
glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Functionally, this transport system is involved in osmoregulation. Under conditions of stress, the organism recruits these transport system to accumulate glycine betaine and other solutes which offer osmo-protection. It has been demonstrated that glycine betaine uptake is accompanied by symport with sodium ions. The locus has been named variously as proU or opuA. A gene library from L.lactis functionally complements an E.coli proU mutant. The comlementing locus is similar to a opuA locus in B.sutlis. This clarifies the differences in nomenclature. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 130254 [Multi-domain] Cd Length: 363 Bit Score: 170.03 E-value: 1.51e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 47 GENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILYRDQDIFDQkySKEQL----RTNVGMV 122
Cdd:TIGR01186 4 GGKKGVNDADLAIAKGEIFVIMGLSGSGKSTTVRMLNRLIE-----PTAGQIFIDGENIMKQ--SPVELrevrRKKIGMV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 123 FQQPNPFP-KSIYDNITYGPKIHGIKNKkvldEIVEKSLRGAAIWDeLKDRLHTNAYSLSGGQQQRVCIARCLAIEPEVI 201
Cdd:TIGR01186 77 FQQFALFPhMTILQNTSLGPELLGWPEQ----ERKEKALELLKLVG-LEEYEHRYPDELSGGMQQRVGLARALAAEPDIL 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 202 LMDEPTSALDPISTLRVEELVQELKEKY--TIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNPSNKKTEDYIS 279
Cdd:TIGR01186 152 LMDEAFSALDPLIRDSMQDELKKLQATLqkTIVFITHDLDEAIRIGDRIVIMKAGEIVQVGTPDEILRNPANEYVEEFIG 231
|
.
gi 580041203 280 G 280
Cdd:TIGR01186 232 K 232
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
40-254 |
1.11e-49 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 161.26 E-value: 1.11e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILYRDQDIfdQKYSKEQLRTNV 119
Cdd:cd00267 3 ENLSFRYGGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLK-----PTSGEILIDGKDI--AKLPLEELRRRI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 120 GMVFQqpnpfpksiydnitygpkihgiknkkvldeivekslrgaaiwdelkdrlhtnaysLSGGQQQRVCIARCLAIEPE 199
Cdd:cd00267 76 GYVPQ-------------------------------------------------------LSGGQRQRVALARALLLNPD 100
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 580041203 200 VILMDEPTSALDPISTLRVEELVQEL-KEKYTIIMVTHNMQQAARVSDKTAFFLNG 254
Cdd:cd00267 101 LLLLDEPTSGLDPASRERLLELLRELaEEGRTVIIVTHDPELAELAADRVIVLKDG 156
|
|
| ABC_Pro_Gly_Betaine |
cd03294 |
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ... |
51-280 |
2.44e-49 |
|
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 164.35 E-value: 2.44e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 51 ALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvPsvkTAGKILYRDQDIfdQKYSKEQL----RTNVGMVFQQP 126
Cdd:cd03294 39 GVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIE--P---TSGKVLIDGQDI--AAMSRKELrelrRKKISMVFQSF 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 127 NPFP-KSIYDNITYGPKIHGIkNKKVLDEIVEKSLRGAAiwdeLKDRLHTNAYSLSGGQQQRVCIARCLAIEPEVILMDE 205
Cdd:cd03294 112 ALLPhRTVLENVAFGLEVQGV-PRAEREERAAEALELVG----LEGWEHKYPDELSGGMQQRVGLARALAVDPDILLMDE 186
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 580041203 206 PTSALDP-ISTLRVEELVQ-ELKEKYTIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNPSNKKTEDYISG 280
Cdd:cd03294 187 AFSALDPlIRREMQDELLRlQAELQKTIVFITHDLDEALRLGDRIAIMKDGRLVQVGTPEEILTNPANDYVREFFRG 263
|
|
| MalK |
COG3839 |
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ... |
40-271 |
3.47e-49 |
|
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];
Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 166.02 E-value: 3.47e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTyikTLnRMV---ELVpsvkTAGKILYRDQDIFDQKYSKeqlR 116
Cdd:COG3839 7 ENVSKSYGGVEALKDIDLDIEDGEFLVLLGPSGCGKST---LL-RMIaglEDP----TSGEILIGGRDVTDLPPKD---R 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 117 tNVGMVFQQPNPFP-KSIYDNITYGPKIHGIKnKKVLDEIVEKslrgAA----IwDELKDRLhtnAYSLSGGQQQRVCIA 191
Cdd:COG3839 76 -NIAMVFQSYALYPhMTVYENIAFPLKLRKVP-KAEIDRRVRE----AAellgL-EDLLDRK---PKQLSGGQRQRVALG 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 192 RCLAIEPEVILMDEPTSALDPisTLRVE------ELVQELkeKYTIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKI 265
Cdd:COG3839 146 RALVREPKVFLLDEPLSNLDA--KLRVEmraeikRLHRRL--GTTTIYVTHDQVEAMTLADRIAVMNDGRIQQVGTPEEL 221
|
....*.
gi 580041203 266 FSNPSN 271
Cdd:COG3839 222 YDRPAN 227
|
|
| glnQ |
PRK09493 |
glutamine ABC transporter ATP-binding protein GlnQ; |
40-278 |
8.60e-49 |
|
glutamine ABC transporter ATP-binding protein GlnQ;
Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 161.80 E-value: 8.60e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELvpsvkTAGKILYRDQDIFDQKYSKEQLRTNV 119
Cdd:PRK09493 5 KNVSKHFGPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEI-----TSGDLIVDGLKVNDPKVDERLIRQEA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 120 GMVFQQPNPFPK-SIYDNITYGPkIHGIKNKKVLDEIVEKSLRGAAiwdELKDRLHTNAYSLSGGQQQRVCIARCLAIEP 198
Cdd:PRK09493 80 GMVFQQFYLFPHlTALENVMFGP-LRVRGASKEEAEKQARELLAKV---GLAERAHHYPSELSGGQQQRVAIARALAVKP 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 199 EVILMDEPTSALDPisTLRVEEL--VQELKEK-YTIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNPSNKKTE 275
Cdd:PRK09493 156 KLMLFDEPTSALDP--ELRHEVLkvMQDLAEEgMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDGDPQVLIKNPPSQRLQ 233
|
...
gi 580041203 276 DYI 278
Cdd:PRK09493 234 EFL 236
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
52-208 |
1.51e-48 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 158.19 E-value: 1.51e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 52 LQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILYRDQDIfdQKYSKEQLRTNVGMVFQQPNPFP- 130
Cdd:pfam00005 1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLS-----PTEGTILLDGQDL--TDDERKSLRKEIGYVFQDPQLFPr 73
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 580041203 131 KSIYDNITYGPKIHGIKnKKVLDEIVEKSLRGAAIWDELKDRLHTNAYSLSGGQQQRVCIARCLAIEPEVILMDEPTS 208
Cdd:pfam00005 74 LTVRENLRLGLLLKGLS-KREKDARAEEALEKLGLGDLADRPVGERPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
40-269 |
5.72e-48 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 166.62 E-value: 5.72e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWY--GENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRmveLVP-SVKTAGKILYRDQDIFDqkYSKEQLR 116
Cdd:COG1123 8 RDLSVRYpgGDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMG---LLPhGGRISGEVLLDGRDLLE--LSEALRG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 117 TNVGMVFQQP--NPFPKSIYDNITYGPKIHGIkNKKVLDEIVEKSLRGAAIWDELKDRLHTnaysLSGGQQQRVCIARCL 194
Cdd:COG1123 83 RRIGMVFQDPmtQLNPVTVGDQIAEALENLGL-SRAEARARVLELLEAVGLERRLDRYPHQ----LSGGQRQRVAIAMAL 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 580041203 195 AIEPEVILMDEPTSALDPISTLRVEELVQELKEKY--TIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNP 269
Cdd:COG1123 158 ALDPDLLIADEPTTALDVTTQAEILDLLRELQRERgtTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPEEILAAP 234
|
|
| ArtP |
COG4161 |
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism]; |
40-279 |
6.90e-48 |
|
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443326 [Multi-domain] Cd Length: 242 Bit Score: 159.79 E-value: 6.90e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMvelvpSVKTAGKILYRDQDI-FDQKYSKEQ---L 115
Cdd:COG4161 6 KNINCFYGSHQALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLL-----ETPDSGQLNIAGHQFdFSQKPSEKAirlL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 116 RTNVGMVFQQPNPFPK-SIYDNITYGP-KIHGIKNKKVLDEIVE--KSLRgaaiwdeLKDRLHTNAYSLSGGQQQRVCIA 191
Cdd:COG4161 81 RQKVGMVFQQYNLWPHlTVMENLIEAPcKVLGLSKEQAREKAMKllARLR-------LTDKADRFPLHLSGGQQQRVAIA 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 192 RCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEK-YTIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDkIFSNPS 270
Cdd:COG4161 154 RALMMEPQVLLFDEPTAALDPEITAQVVEIIRELSQTgITQVIVTHEVEFARKVASQVVYMEKGRIIEQGDAS-HFTQPQ 232
|
....*....
gi 580041203 271 NKKTEDYIS 279
Cdd:COG4161 233 TEAFAHYLS 241
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
47-254 |
2.51e-47 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 155.62 E-value: 2.51e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 47 GENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELvpsvkTAGKILYRDQDIfdQKYSKEQLRTNVGMVFQQP 126
Cdd:cd03228 13 RPKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDP-----TSGEILIDGVDL--RDLDLESLRKNIAYVPQDP 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 127 NPFPKSIYDNItygpkihgiknkkvldeivekslrgaaiwdelkdrlhtnaysLSGGQQQRVCIARCLAIEPEVILMDEP 206
Cdd:cd03228 86 FLFSGTIRENI------------------------------------------LSGGQRQRIAIARALLRDPPILILDEA 123
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 580041203 207 TSALDPISTLRVEELVQELKEKYTIIMVTHNMQQAARVsDKTAFFLNG 254
Cdd:cd03228 124 TSALDPETEALILEALRALAKGKTVIVIAHRLSTIRDA-DRIIVLDDG 170
|
|
| artP |
PRK11124 |
arginine transporter ATP-binding subunit; Provisional |
40-279 |
2.76e-47 |
|
arginine transporter ATP-binding subunit; Provisional
Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 158.25 E-value: 2.76e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMvelvpSVKTAGKiLYRDQDIFDqkYSKE------ 113
Cdd:PRK11124 6 NGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLL-----EMPRSGT-LNIAGNHFD--FSKTpsdkai 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 114 -QLRTNVGMVFQQPNPFPK-SIYDNITYGPKihgiknkKVLDEIVEKSLRGAaiwDELKDRLHTNAYS------LSGGQQ 185
Cdd:PRK11124 78 rELRRNVGMVFQQYNLWPHlTVQQNLIEAPC-------RVLGLSKDQALARA---EKLLERLRLKPYAdrfplhLSGGQQ 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 186 QRVCIARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKE-KYTIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDK 264
Cdd:PRK11124 148 QRVAIARALMMEPQVLLFDEPTAALDPEITAQIVSIIRELAEtGITQVIVTHEVEVARKTASRVVYMENGHIVEQGDASC 227
|
250
....*....|....*
gi 580041203 265 iFSNPSNKKTEDYIS 279
Cdd:PRK11124 228 -FTQPQTEAFKNYLS 241
|
|
| HisP |
COG4598 |
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism]; |
46-282 |
3.42e-47 |
|
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443652 [Multi-domain] Cd Length: 259 Bit Score: 158.43 E-value: 3.42e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 46 YGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNrMVElVPsvkTAGKILYRDQDI------------FDQKySKE 113
Cdd:COG4598 18 FGDLEVLKGVSLTARKGDVISIIGSSGSGKSTFLRCIN-LLE-TP---DSGEIRVGGEEIrlkpdrdgelvpADRR-QLQ 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 114 QLRTNVGMVFQQPNPFP-KSIYDNITYGPkIHGIKNKKvlDEIVEkslRGAAIWDE--LKDRLHtnAY--SLSGGQQQRV 188
Cdd:COG4598 92 RIRTRLGMVFQSFNLWShMTVLENVIEAP-VHVLGRPK--AEAIE---RAEALLAKvgLADKRD--AYpaHLSGGQQQRA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 189 CIARCLAIEPEVILMDEPTSALDPistlrveELVQE-LK-------EKYTIIMVTHNMQQAARVSDKTAFFLNGYVNEYD 260
Cdd:COG4598 164 AIARALAMEPEVMLFDEPTSALDP-------ELVGEvLKvmrdlaeEGRTMLVVTHEMGFARDVSSHVVFLHQGRIEEQG 236
|
250 260
....*....|....*....|..
gi 580041203 261 DTDKIFSNPSNKKTEDYISGRF 282
Cdd:COG4598 237 PPAEVFGNPKSERLRQFLSSSL 258
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
47-236 |
1.52e-46 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 165.78 E-value: 1.52e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 47 GENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELvpsvkTAGKILYRDQDIfdQKYSKEQLRTNVGMVFQQP 126
Cdd:COG2274 486 DSPPVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEP-----TSGRILIDGIDL--RQIDPASLRRQIGVVLQDV 558
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 127 NPFPKSIYDNITYGpkihgikNKKVLDEIVEKSLRGAAIWDE---LKDRLHT----NAYSLSGGQQQRVCIARCLAIEPE 199
Cdd:COG2274 559 FLFSGTIRENITLG-------DPDATDEEIIEAARLAGLHDFieaLPMGYDTvvgeGGSNLSGGQRQRLAIARALLRNPR 631
|
170 180 190
....*....|....*....|....*....|....*..
gi 580041203 200 VILMDEPTSALDPISTLRVEELVQELKEKYTIIMVTH 236
Cdd:COG2274 632 ILILDEATSALDAETEAIILENLRRLLKGRTVIIIAH 668
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
52-279 |
1.35e-45 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 154.14 E-value: 1.35e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 52 LQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELVPSVKTAGKI-LYRDQDIFDQKYSKEQLRTNVGMVFQQPNPFP 130
Cdd:PRK11264 19 LHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRVGDItIDTARSLSQQKGLIRQLRQHVGFVFQNFNLFP 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 131 -KSIYDNITYGPKIhgiknkkvldeiVEKSLRGAAIwdELKDRL--------HTNAY--SLSGGQQQRVCIARCLAIEPE 199
Cdd:PRK11264 99 hRTVLENIIEGPVI------------VKGEPKEEAT--ARARELlakvglagKETSYprRLSGGQQQRVAIARALAMRPE 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 200 VILMDEPTSALDPistlrveELVQEL--------KEKYTIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNPSN 271
Cdd:PRK11264 165 VILFDEPTSALDP-------ELVGEVlntirqlaQEKRTMVIVTHEMSFARDVADRAIFMDQGRIVEQGPAKALFADPQQ 237
|
....*...
gi 580041203 272 KKTEDYIS 279
Cdd:PRK11264 238 PRTRQFLE 245
|
|
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
46-236 |
2.57e-45 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 160.72 E-value: 2.57e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 46 YGENH-ALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELvpsvkTAGKILYRDQDIfdQKYSKEQLRTNVGMVFQ 124
Cdd:COG1132 349 YPGDRpVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDP-----TSGRILIDGVDI--RDLTLESLRRQIGVVPQ 421
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 125 QPNPFPKSIYDNITYGpkihgikNKKVLDEIVEKSLRGAAIWD---ELKDRLHT----NAYSLSGGQQQRVCIARCLAIE 197
Cdd:COG1132 422 DTFLFSGTIRENIRYG-------RPDATDEEVEEAAKAAQAHEfieALPDGYDTvvgeRGVNLSGGQRQRIAIARALLKD 494
|
170 180 190
....*....|....*....|....*....|....*....
gi 580041203 198 PEVILMDEPTSALDPISTLRVEELVQELKEKYTIIMVTH 236
Cdd:COG1132 495 PPILILDEATSALDTETEALIQEALERLMKGRTTIVIAH 533
|
|
| ECF_ATPase_1 |
TIGR04520 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
47-270 |
3.22e-45 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275313 [Multi-domain] Cd Length: 268 Bit Score: 153.35 E-value: 3.22e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 47 GENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMveLVPsvkTAGKILYRDQDIFDQKYSKEqLRTNVGMVFQQP 126
Cdd:TIGR04520 13 SEKPALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGL--LLP---TSGKVTVDGLDTLDEENLWE-IRKKVGMVFQNP 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 127 -NPFPKSIY-DNITYGPKIHGIKNKKVLdEIVEKSLRGAaiwdELKDRLHTNAYSLSGGQQQRVCIARCLAIEPEVILMD 204
Cdd:TIGR04520 87 dNQFVGATVeDDVAFGLENLGVPREEMR-KRVDEALKLV----GMEDFRDREPHLLSGGQKQRVAIAGVLAMRPDIIILD 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 580041203 205 EPTSALDPISTLRVEELVQELKEKY--TIIMVTHNMQQAARvSDKTAFFLNGYVnEYDDTDK-IFSNPS 270
Cdd:TIGR04520 162 EATSMLDPKGRKEVLETIRKLNKEEgiTVISITHDMEEAVL-ADRVIVMNKGKI-VAEGTPReIFSQVE 228
|
|
| ABC_PhnC_transporter |
cd03256 |
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ... |
40-247 |
3.37e-45 |
|
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 152.72 E-value: 3.37e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGEN-HALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELvpsvkTAGKILYRDQDI-FDQKYSKEQLRT 117
Cdd:cd03256 4 ENLSKTYPNGkKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEP-----TSGSVLIDGTDInKLKGKALRQLRR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 118 NVGMVFQQPNPFPK-SIYDNITYG-----PKIHGIKNKKVLDEIveksLRGAAIWDE--LKDRLHTNAYSLSGGQQQRVC 189
Cdd:cd03256 79 QIGMIFQQFNLIERlSVLENVLSGrlgrrSTWRSLFGLFPKEEK----QRALAALERvgLLDKAYQRADQLSGGQQQRVA 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 190 IARCLAIEPEVILMDEPTSALDPISTLRVEELVQEL--KEKYTIIMVTHNMQQAARVSDK 247
Cdd:cd03256 155 IARALMQQPKLILADEPVASLDPASSRQVMDLLKRInrEEGITVIVSLHQVDLAREYADR 214
|
|
| ABC_ModC_like |
cd03299 |
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ... |
40-279 |
5.09e-45 |
|
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 152.10 E-value: 5.09e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGENHaLQNINLDIYENQITAIIGPSGCGKSTYIKTLnrMVELVPSvktAGKILYRDQDIFDQKYSKEqlrtNV 119
Cdd:cd03299 4 ENLSKDWKEFK-LKNVSLEVERGDYFVILGPTGSGKSVLLETI--AGFIKPD---SGKILLNGKDITNLPPEKR----DI 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 120 GMVFQQPNPFP-KSIYDNITYGpkihgIKNKKVLDEIVEKSLRGAAIWDELKDRLHTNAYSLSGGQQQRVCIARCLAIEP 198
Cdd:cd03299 74 SYVPQNYALFPhMTVYKNIAYG-----LKKRKVDKKEIERKVLEIAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNP 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 199 EVILMDEPTSALDPISTLRVEELVQELKEKY--TIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNPSNKKTED 276
Cdd:cd03299 149 KILLLDEPFSALDVRTKEKLREELKKIRKEFgvTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEEVFKKPKNEFVAE 228
|
...
gi 580041203 277 YIS 279
Cdd:cd03299 229 FLG 231
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
38-256 |
6.20e-45 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 151.43 E-value: 6.20e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 38 STQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLnrmVELVPSvkTAGKILYRDQDIFDQKySKEQLRT 117
Cdd:cd03224 2 EVENLNAGYGKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTI---MGLLPP--RSGSIRFDGRDITGLP-PHERARA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 118 NVGMVFQQPNPFPK-SIYDNITYGPKIHGI-KNKKVLDEIVEkslrgaaIWDELKDRLHTNAYSLSGGQQQRVCIARCLA 195
Cdd:cd03224 76 GIGYVPEGRRIFPElTVEENLLLGAYARRRaKRKARLERVYE-------LFPRLKERRKQLAGTLSGGEQQMLAIARALM 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 580041203 196 IEPEVILMDEPTSALDPISTLRVEELVQELKEK-YTIIMVTHNMQQAARVSDktafflNGYV 256
Cdd:cd03224 149 SRPKLLLLDEPSEGLAPKIVEEIFEAIRELRDEgVTILLVEQNARFALEIAD------RAYV 204
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
38-254 |
7.02e-45 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 149.89 E-value: 7.02e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 38 STQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELvpsvkTAGKILYRDQDIfdQKYSKEQLRT 117
Cdd:cd03214 1 EVENLSVGYGGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKP-----SSGEILLDGKDL--ASLSPKELAR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 118 NVGMVFQqpnpfpksiydnitygpkihgiknkkVLDEIvekslrGAAiwdELKDRLHTnaySLSGGQQQRVCIARCLAIE 197
Cdd:cd03214 74 KIAYVPQ--------------------------ALELL------GLA---HLADRPFN---ELSGGERQRVLLARALAQE 115
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 580041203 198 PEVILMDEPTSALDPISTLRVEELVQELKEKY--TIIMVTHNMQQAARVSDKTAFFLNG 254
Cdd:cd03214 116 PPILLLDEPTSHLDIAHQIELLELLRRLARERgkTVVMVLHDLNLAARYADRVILLKDG 174
|
|
| PhnC |
COG3638 |
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ... |
47-246 |
8.46e-45 |
|
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 442855 [Multi-domain] Cd Length: 249 Bit Score: 151.75 E-value: 8.46e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 47 GENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELvpsvkTAGKILYRDQDIfdQKYSKEQL---RTNVGMVF 123
Cdd:COG3638 14 GGTPALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEP-----TSGEILVDGQDV--TALRGRALrrlRRRIGMIF 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 124 QQPNPFPK-SIYDNITYG--PKIHGIKnkkvldeivekSLRG--------AAIW--DE--LKDRLHTNAYSLSGGQQQRV 188
Cdd:COG3638 87 QQFNLVPRlSVLTNVLAGrlGRTSTWR-----------SLLGlfppedreRALEalERvgLADKAYQRADQLSGGQQQRV 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 189 CIARCLAIEPEVILMDEPTSALDPISTLRVEELVQEL--KEKYTIIMVTHNMQQAARVSD 246
Cdd:COG3638 156 AIARALVQEPKLILADEPVASLDPKTARQVMDLLRRIarEDGITVVVNLHQVDLARRYAD 215
|
|
| FtsE |
COG2884 |
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning]; |
40-244 |
2.46e-44 |
|
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 149.82 E-value: 2.46e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGENH-ALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRmvELVPsvkTAGKILYRDQDIFDQKYSK-EQLRT 117
Cdd:COG2884 5 ENVSKRYPGGReALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYG--EERP---TSGQVLVNGQDLSRLKRREiPYLRR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 118 NVGMVFQQ----PNpfpKSIYDNITYGPKIHGiKNKKVLDEIVEKSLRgaaiWDELKDRLHTNAYSLSGGQQQRVCIARC 193
Cdd:COG2884 80 RIGVVFQDfrllPD---RTVYENVALPLRVTG-KSRKEIRRRVREVLD----LVGLSDKAKALPHELSGGEQQRVAIARA 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 580041203 194 LAIEPEVILMDEPTSALDPISTLRVEELVQEL-KEKYTIIMVTHNM----QQAARV 244
Cdd:COG2884 152 LVNRPELLLADEPTGNLDPETSWEIMELLEEInRRGTTVLIATHDLelvdRMPKRV 207
|
|
| ProV |
COG4175 |
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ... |
51-282 |
2.55e-44 |
|
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443334 [Multi-domain] Cd Length: 389 Bit Score: 154.49 E-value: 2.55e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 51 ALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvPsvkTAGKILYRDQDIFdqKYSKEQL----RTNVGMVFQQ- 125
Cdd:COG4175 42 GVNDASFDVEEGEIFVIMGLSGSGKSTLVRCLNRLIE--P---TAGEVLIDGEDIT--KLSKKELrelrRKKMSMVFQHf 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 126 ---PNpfpKSIYDNITYGPKIHGIkNKKVLDEIVEKSLR--GAAIWDelkdrlhtNAY--SLSGGQQQRVCIARCLAIEP 198
Cdd:COG4175 115 allPH---RTVLENVAFGLEIQGV-PKAERRERAREALElvGLAGWE--------DSYpdELSGGMQQRVGLARALATDP 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 199 EVILMDEPTSALDPIstLRVE------ELVQELKeKyTIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNPSNk 272
Cdd:COG4175 183 DILLMDEAFSALDPL--IRREmqdellELQAKLK-K-TIVFITHDLDEALRLGDRIAIMKDGRIVQIGTPEEILTNPAN- 257
|
250
....*....|
gi 580041203 273 kteDYISgRF 282
Cdd:COG4175 258 ---DYVA-DF 263
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
40-267 |
4.49e-44 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 149.85 E-value: 4.49e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTlnrMVELVPsvKTAGKILYRDQDIfdqkyskEQLRTNV 119
Cdd:COG1121 10 ENLTVSYGGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKA---ILGLLP--PTSGTVRLFGKPP-------RRARRRI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 120 GMVFQQPN---PFPKSIYDNITYG--PKIHGIKN-KKVLDEIVEKSLR--GAAiwdELKDR-LHTnaysLSGGQQQRVCI 190
Cdd:COG1121 78 GYVPQRAEvdwDFPITVRDVVLMGryGRRGLFRRpSRADREAVDEALErvGLE---DLADRpIGE----LSGGQQQRVLL 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 580041203 191 ARCLAIEPEVILMDEPTSALDPISTLRVEELVQEL-KEKYTIIMVTHNMQQAARVSDKTAfFLNGYVNEYDDTDKIFS 267
Cdd:COG1121 151 ARALAQDPDLLLLDEPFAGVDAATEEALYELLRELrREGKTILVVTHDLGAVREYFDRVL-LLNRGLVAHGPPEEVLT 227
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
46-278 |
6.81e-44 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 148.92 E-value: 6.81e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 46 YGENHALQNINLDIYENQITAIIGPSGCGKSTyikTLnRMVELVPSVkTAGKILYRDQDIFDQKYSKEQlrtnVGMVFQQ 125
Cdd:cd03300 10 YGGFVALDGVSLDIKEGEFFTLLGPSGCGKTT---LL-RLIAGFETP-TSGEILLDGKDITNLPPHKRP----VNTVFQN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 126 PNPFPK-SIYDNITYGPKIHGIKnKKVLDEIVEKSLRGAaiwdELKDRLHTNAYSLSGGQQQRVCIARCLAIEPEVILMD 204
Cdd:cd03300 81 YALFPHlTVFENIAFGLRLKKLP-KAEIKERVAEALDLV----QLEGYANRKPSQLSGGQQQRVAIARALVNEPKVLLLD 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 580041203 205 EPTSALDpiSTLRvEELVQELKEKY-----TIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNPSNKKTEDYI 278
Cdd:cd03300 156 EPLGALD--LKLR-KDMQLELKRLQkelgiTFVFVTHDQEEALTMSDRIAVMNKGKIQQIGTPEEIYEEPANRFVADFI 231
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
38-254 |
9.02e-44 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 146.77 E-value: 9.02e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 38 STQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILYRDQDIFDQKyskEQLRT 117
Cdd:cd03230 2 EVRNLSKRYGKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLK-----PDSGEIKVLGKDIKKEP---EEVKR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 118 NVGMVFQQPNPFPK-SIYDNITYgpkihgiknkkvldeivekslrgaaiwdelkdrlhtnayslSGGQQQRVCIARCLAI 196
Cdd:cd03230 74 RIGYLPEEPSLYENlTVRENLKL-----------------------------------------SGGMKQRLALAQALLH 112
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 580041203 197 EPEVILMDEPTSALDPISTLRVEELVQELKEKY-TIIMVTHNMQQAARVSDKTAFFLNG 254
Cdd:cd03230 113 DPELLILDEPTSGLDPESRREFWELLRELKKEGkTILLSSHILEEAERLCDRVAILNNG 171
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
48-247 |
1.29e-42 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 147.50 E-value: 1.29e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 48 ENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILYRDQDIFDQKYSKEQLRTNVGMVFQQP- 126
Cdd:PRK13637 19 EKKALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLK-----PTSGKIIIDGVDITDKKVKLSDIRKKVGLVFQYPe 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 127 -NPFPKSIYDNITYGPKIHGIKNKKVLDEiVEKSLRGAAI-WDELKDRlhtNAYSLSGGQQQRVCIARCLAIEPEVILMD 204
Cdd:PRK13637 94 yQLFEETIEKDIAFGPINLGLSEEEIENR-VKRAMNIVGLdYEDYKDK---SPFELSGGQKRRVAIAGVVAMEPKILILD 169
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 580041203 205 EPTSALDPISTLRVEELVQELKEKY--TIIMVTHNMQQAARVSDK 247
Cdd:PRK13637 170 EPTAGLDPKGRDEILNKIKELHKEYnmTIILVSHSMEDVAKLADR 214
|
|
| CysA |
COG1118 |
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ... |
40-271 |
3.56e-42 |
|
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 147.60 E-value: 3.56e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTyikTLnRMVE--LVPsvkTAGKILYRDQDIFDQKYSKEqlRt 117
Cdd:COG1118 6 RNISKRFGSFTLLDDVSLEIASGELVALLGPSGSGKTT---LL-RIIAglETP---DSGRIVLNGRDLFTNLPPRE--R- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 118 NVGMVFQQPNPFPK-SIYDNITYGPKIHGiKNKKVLDEIVEKSLR--GAaiwDELKDRLHTNaysLSGGQQQRVCIARCL 194
Cdd:COG1118 76 RVGFVFQHYALFPHmTVAENIAFGLRVRP-PSKAEIRARVEELLElvQL---EGLADRYPSQ---LSGGQRQRVALARAL 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 195 AIEPEVILMDEPTSALDpiSTLRvEELVQELKE-----KYTIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNP 269
Cdd:COG1118 149 AVEPEVLLLDEPFGALD--AKVR-KELRRWLRRlhdelGGTTVFVTHDQEEALELADRVVVMNQGRIEQVGTPDEVYDRP 225
|
..
gi 580041203 270 SN 271
Cdd:COG1118 226 AT 227
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
46-256 |
4.06e-42 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 143.93 E-value: 4.06e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 46 YGENHALQNINLDIYENQITAIIGPSGCGKSTyikTLnRMVELVPSVkTAGKILYRDQDIFDQkYSKEQlrtNVGMVFQQ 125
Cdd:cd03301 10 FGNVTALDDLNLDIADGEFVVLLGPSGCGKTT---TL-RMIAGLEEP-TSGRIYIGGRDVTDL-PPKDR---DIAMVFQN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 126 PNPFP-KSIYDNITYGPKIHGIKNkkvlDEIVEKSLRGAAIW--DELKDRLHTnaySLSGGQQQRVCIARCLAIEPEVIL 202
Cdd:cd03301 81 YALYPhMTVYDNIAFGLKLRKVPK----DEIDERVREVAELLqiEHLLDRKPK---QLSGGQRQRVALGRAIVREPKVFL 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 580041203 203 MDEPTSALDpiSTLRVE---ELVQELKE-KYTIIMVTHNMQQAARVSDKTAFFLNGYV 256
Cdd:cd03301 154 MDEPLSNLD--AKLRVQmraELKRLQQRlGTTTIYVTHDQVEAMTMADRIAVMNDGQI 209
|
|
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
47-254 |
1.69e-41 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 142.26 E-value: 1.69e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 47 GENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVelvpsVKTAGKILYRDQDIfdqKYSKEQLRTNVGMVFQQP 126
Cdd:cd03263 13 GTKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGEL-----RPTSGTAYINGYSI---RTDRKAARQSLGYCPQFD 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 127 NPFPK-SIYDNITYGPKIHGIKNKKVlDEIVEKSLRGaaiwDELKDRLHTNAYSLSGGQQQRVCIARCLAIEPEVILMDE 205
Cdd:cd03263 85 ALFDElTVREHLRFYARLKGLPKSEI-KEEVELLLRV----LGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVLLLDE 159
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 580041203 206 PTSALDPISTLRVEELVQELKEKYTIIMVTHNMQQAARVSDKTAFFLNG 254
Cdd:cd03263 160 PTSGLDPASRRAIWDLILEVRKGRSIILTTHSMDEAEALCDRIAIMSDG 208
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
38-247 |
2.04e-41 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 142.58 E-value: 2.04e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 38 STQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMveLVPsvkTAGKILYRDQDIfDQKysKEQLRT 117
Cdd:cd03219 2 EVRGLTKRFGGLVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGF--LRP---TSGSVLFDGEDI-TGL--PPHEIA 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 118 NVGMV--FQQPNPFPK-SIYDNI------TYGPKIHGIKNKKVLDEIVEKSLRGAAIWdELKDRLHTNAYSLSGGQQQRV 188
Cdd:cd03219 74 RLGIGrtFQIPRLFPElTVLENVmvaaqaRTGSGLLLARARREEREARERAEELLERV-GLADLADRPAGELSYGQQRRL 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 189 CIARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEK-YTIIMVTHNMQQAARVSDK 247
Cdd:cd03219 153 EIARALATDPKLLLLDEPAAGLNPEETEELAELIRELRERgITVLLVEHDMDVVMSLADR 212
|
|
| metN |
PRK11153 |
DL-methionine transporter ATP-binding subunit; Provisional |
50-279 |
5.44e-41 |
|
DL-methionine transporter ATP-binding subunit; Provisional
Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 144.56 E-value: 5.44e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 50 HALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvPsvkTAGKILYRDQDIfdQKYSKEQLRT---NVGMVFQQP 126
Cdd:PRK11153 19 HALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLER--P---TSGRVLVDGQDL--TALSEKELRKarrQIGMIFQHF 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 127 NPFP-KSIYDNITYGPKIHGIK----NKKVLD--EIVEkslrgaaiwdeLKDrlHTNAY--SLSGGQQQRVCIARCLAIE 197
Cdd:PRK11153 92 NLLSsRTVFDNVALPLELAGTPkaeiKARVTEllELVG-----------LSD--KADRYpaQLSGGQKQRVAIARALASN 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 198 PEVILMDEPTSALDPISTLRVEELVQELKEKY--TIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNPSNKKTE 275
Cdd:PRK11153 159 PKVLLCDEATSALDPATTRSILELLKDINRELglTIVLITHEMDVVKRICDRVAVIDAGRLVEQGTVSEVFSHPKHPLTR 238
|
....
gi 580041203 276 DYIS 279
Cdd:PRK11153 239 EFIQ 242
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
38-249 |
8.71e-41 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 140.36 E-value: 8.71e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 38 STQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLnrmVELVPsvKTAGKIlyrdqDIFDQKYSKEQLRt 117
Cdd:cd03235 1 EVEDLTVSYGGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAI---LGLLK--PTSGSI-----RVFGKPLEKERKR- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 118 nVGMVFQQPN---PFPKSIYDNIT---YGPKIHGIKNKKVLDEIVEKSLR--GAAiwdELKDRLHTnaySLSGGQQQRVC 189
Cdd:cd03235 70 -IGYVPQRRSidrDFPISVRDVVLmglYGHKGLFRRLSKADKAKVDEALErvGLS---ELADRQIG---ELSGGQQQRVL 142
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 580041203 190 IARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEK-YTIIMVTHNMQQAARVSDKTA 249
Cdd:cd03235 143 LARALVQDPDLLLLDEPFAGVDPKTQEDIYELLRELRREgMTILVVTHDLGLVLEYFDRVL 203
|
|
| ABC_phnC |
TIGR02315 |
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ... |
41-278 |
1.01e-39 |
|
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]
Pssm-ID: 131368 [Multi-domain] Cd Length: 243 Bit Score: 138.59 E-value: 1.01e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 41 NLDLWYGENH-ALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELvpsvkTAGKILYRDQDIFD-QKYSKEQLRTN 118
Cdd:TIGR02315 6 NLSKVYPNGKqALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEP-----SSGSILLEGTDITKlRGKKLRKLRRR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 119 VGMVFQQPNPFP-KSIYDNITYG-----PKIHGI------KNKKVLDEIVEKSlrgaaiwdELKDRLHTNAYSLSGGQQQ 186
Cdd:TIGR02315 81 IGMIFQHYNLIErLTVLENVLHGrlgykPTWRSLlgrfseEDKERALSALERV--------GLADKAYQRADQLSGGQQQ 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 187 RVCIARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEKY--TIIMVTHNMQQAARVSDKTAFFLNGYVneyddtdk 264
Cdd:TIGR02315 153 RVAIARALAQQPDLILADEPIASLDPKTSKQVMDYLKRINKEDgiTVIINLHQVDLAKKYADRIVGLKAGEI-------- 224
|
250
....*....|....
gi 580041203 265 IFSNPSNKKTEDYI 278
Cdd:TIGR02315 225 VFDGAPSELDDEVL 238
|
|
| PRK10619 |
PRK10619 |
histidine ABC transporter ATP-binding protein HisP; |
46-280 |
1.18e-39 |
|
histidine ABC transporter ATP-binding protein HisP;
Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 138.95 E-value: 1.18e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 46 YGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLN---RMVELVPSVKTAGKILYRDQD----IFDQKySKEQLRTN 118
Cdd:PRK10619 15 YGEHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINfleKPSEGSIVVNGQTINLVRDKDgqlkVADKN-QLRLLRTR 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 119 VGMVFQQPNPFPK-SIYDNITYGP-KIHGIkNKKVLDEIVEKSLRGAAIWDELKDRLHTNaysLSGGQQQRVCIARCLAI 196
Cdd:PRK10619 94 LTMVFQHFNLWSHmTVLENVMEAPiQVLGL-SKQEARERAVKYLAKVGIDERAQGKYPVH---LSGGQQQRVSIARALAM 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 197 EPEVILMDEPTSALDPISTLRVEELVQELKEK-YTIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNPSNKKTE 275
Cdd:PRK10619 170 EPEVLLFDEPTSALDPELVGEVLRIMQQLAEEgKTMVVVTHEMGFARHVSSHVIFLHQGKIEEEGAPEQLFGNPQSPRLQ 249
|
....*
gi 580041203 276 DYISG 280
Cdd:PRK10619 250 QFLKG 254
|
|
| ThiQ |
COG3840 |
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism]; |
43-278 |
2.26e-39 |
|
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 137.19 E-value: 2.26e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 43 DLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYiktLNrMVE--LVPsvkTAGKILYRDQDIfdqkyskeqLRTN-- 118
Cdd:COG3840 6 DLTYRYGDFPLRFDLTIAAGERVAILGPSGAGKSTL---LN-LIAgfLPP---DSGRILWNGQDL---------TALPpa 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 119 ---VGMVFQQPNPFPK-SIYDNITYGpkIH-GIK----NKKVLDEIVEK-SLrgaaiwDELKDRLhtnAYSLSGGQQQRV 188
Cdd:COG3840 70 erpVSMLFQENNLFPHlTVAQNIGLG--LRpGLKltaeQRAQVEQALERvGL------AGLLDRL---PGQLSGGQRQRV 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 189 CIARCLAIEPEVILMDEPTSALDPIstLRVE--ELVQELKEKY--TIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDK 264
Cdd:COG3840 139 ALARCLVRKRPILLLDEPFSALDPA--LRQEmlDLVDELCRERglTVLMVTHDPEDAARIADRVLLVADGRIAADGPTAA 216
|
250
....*....|....
gi 580041203 265 IFSNPSNKKTEDYI 278
Cdd:COG3840 217 LLDGEPPPALAAYL 230
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
48-258 |
4.43e-39 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 136.52 E-value: 4.43e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 48 ENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELvpsvkTAGKILYRDQDIfdQKYSKEQLRTNVGMVFQQPN 127
Cdd:cd03249 15 DVPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDP-----TSGEILLDGVDI--RDLNLRWLRSQIGLVSQEPV 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 128 PFPKSIYDNITYGpkihgiKNKKVLDEiVEKSLRGAAIWD---ELKDRLHT----NAYSLSGGQQQRVCIARCLAIEPEV 200
Cdd:cd03249 88 LFDGTIAENIRYG------KPDATDEE-VEEAAKKANIHDfimSLPDGYDTlvgeRGSQLSGGQKQRIAIARALLRNPKI 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 580041203 201 ILMDEPTSALDPISTLRVEELVQELKEKYTIIMVTHNMqQAARVSDKTAFFLNGYVNE 258
Cdd:cd03249 161 LLLDEATSALDAESEKLVQEALDRAMKGRTTIVIAHRL-STIRNADLIAVLQNGQVVE 217
|
|
| CydD |
COG4988 |
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ... |
40-244 |
6.55e-39 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 142.97 E-value: 6.55e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGENH-ALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELvpsvkTAGKILYRDQDIFDqkYSKEQLRTN 118
Cdd:COG4988 340 EDVSFSYPGGRpALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPP-----YSGSILINGVDLSD--LDPASWRRQ 412
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 119 VGMVFQQPNPFPKSIYDNITYGpkihgikNKKVLDEIVEKSLRGAAIWD---ELKDRLHT----NAYSLSGGQQQRVCIA 191
Cdd:COG4988 413 IAWVPQNPYLFAGTIRENLRLG-------RPDASDEELEAALEAAGLDEfvaALPDGLDTplgeGGRGLSGGQAQRLALA 485
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 580041203 192 RCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEKYTIIMVTH---NMQQAARV 244
Cdd:COG4988 486 RALLRDAPLLLLDEPTAHLDAETEAEILQALRRLAKGRTVILITHrlaLLAQADRI 541
|
|
| LivG |
COG0411 |
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ... |
38-247 |
1.18e-38 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];
Pssm-ID: 440180 [Multi-domain] Cd Length: 257 Bit Score: 135.94 E-value: 1.18e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 38 STQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMveLVPsvkTAGKILYRDQDIFDQKYSKeqlRT 117
Cdd:COG0411 6 EVRGLTKRFGGLVAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGF--YRP---TSGRILFDGRDITGLPPHR---IA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 118 NVGMV--FQQPNPFPK-SIYDNI-----------TYGPKIHGIKNKKVLDEIVEKSLRGAAIWDeLKDRLHTNAYSLSGG 183
Cdd:COG0411 78 RLGIArtFQNPRLFPElTVLENVlvaaharlgrgLLAALLRLPRARREEREARERAEELLERVG-LADRADEPAGNLSYG 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 580041203 184 QQQRVCIARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKE--KYTIIMVTHNMQQAARVSDK 247
Cdd:COG0411 157 QQRRLEIARALATEPKLLLLDEPAAGLNPEETEELAELIRRLRDerGITILLIEHDMDLVMGLADR 222
|
|
| cbiO |
PRK13634 |
cobalt transporter ATP-binding subunit; Provisional |
48-269 |
1.03e-37 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 134.76 E-value: 1.03e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 48 ENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMveLVPsvkTAGKILYRDQDIFDQKYSKE--QLRTNVGMVFQQ 125
Cdd:PRK13634 19 ERRALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGL--LQP---TSGTVTIGERVITAGKKNKKlkPLRKKVGIVFQF 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 126 PNP--FPKSIYDNITYGPKIHGIKnkkvldeiVEKSLRGAAIWDEL----KDRLHTNAYSLSGGQQQRVCIARCLAIEPE 199
Cdd:PRK13634 94 PEHqlFEETVEKDICFGPMNFGVS--------EEDAKQKAREMIELvglpEELLARSPFELSGGQMRRVAIAGVLAMEPE 165
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 580041203 200 VILMDEPTSALDPISTLRVEELVQEL-KEK-YTIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNP 269
Cdd:PRK13634 166 VLVLDEPTAGLDPKGRKEMMEMFYKLhKEKgLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREIFADP 237
|
|
| LivF |
COG0410 |
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ... |
38-256 |
2.67e-37 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];
Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 132.03 E-value: 2.67e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 38 STQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELvpsvkTAGKILYRDQDIfdqkyskEQLRT 117
Cdd:COG0410 5 EVENLHAGYGGIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPP-----RSGSIRFDGEDI-------TGLPP 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 118 N------VGMVFQQPNPFPK-SIYDNITYGPKIHGIKN--KKVLDEIVEkslrgaaIWDELKDRLHTNAYSLSGGQQQRV 188
Cdd:COG0410 73 HriarlgIGYVPEGRRIFPSlTVEENLLLGAYARRDRAevRADLERVYE-------LFPRLKERRRQRAGTLSGGEQQML 145
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 580041203 189 CIARCLAIEPEVILMDEPTSALDPISTLRVEELVQELK-EKYTIIMVTHNMQQAARVSDKtafflnGYV 256
Cdd:COG0410 146 AIGRALMSRPKLLLLDEPSLGLAPLIVEEIFEIIRRLNrEGVTILLVEQNARFALEIADR------AYV 208
|
|
| PhnT2 |
TIGR03265 |
putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ... |
38-278 |
7.06e-37 |
|
putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ATP-binding protein is found in a number of genomes in operon-like contexts strongly suggesting a substrate specificity for 2-aminoethylphosphonate (2-AEP). The characterized PhnSTUV system is absent in the genomes in which this system is found. These genomes encode systems for the catabolism of 2-AEP, making the need for a 2-AEP-specific transporter likely. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 274496 [Multi-domain] Cd Length: 353 Bit Score: 134.01 E-value: 7.06e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 38 STQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMvelvpSVKTAGKILYRDQDIFDQKYSKEqlrt 117
Cdd:TIGR03265 6 SIDNIRKRFGAFTALKDISLSVKKGEFVCLLGPSGCGKTTLLRIIAGL-----ERQTAGTIYQGGRDITRLPPQKR---- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 118 NVGMVFQQPNPFPK-SIYDNITYGpkIHGIKNKKvlDEIVEKslrgAAIWDELKDRLHT-NAY--SLSGGQQQRVCIARC 193
Cdd:TIGR03265 77 DYGIVFQSYALFPNlTVADNIAYG--LKNRGMGR--AEVAER----VAELLDLVGLPGSeRKYpgQLSGGQQQRVALARA 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 194 LAIEPEVILMDEPTSALDPistlRV-EELVQELKE-----KYTIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFS 267
Cdd:TIGR03265 149 LATSPGLLLLDEPLSALDA----RVrEHLRTEIRQlqrrlGVTTIMVTHDQEEALSMADRIVVMNHGVIEQVGTPQEIYR 224
|
250
....*....|.
gi 580041203 268 NPSNKKTEDYI 278
Cdd:TIGR03265 225 HPATPFVADFV 235
|
|
| CydC |
COG4987 |
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ... |
51-244 |
7.59e-37 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 137.59 E-value: 7.59e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 51 ALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELvpsvkTAGKILYRDQDIfdQKYSKEQLRTNVGMVFQQPNPFP 130
Cdd:COG4987 350 VLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDP-----QSGSITLGGVDL--RDLDEDDLRRRIAVVPQRPHLFD 422
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 131 KSIYDNITYGpkihgikNKKVLDEIVEKSLRGAAIWD---ELKDRLHT----NAYSLSGGQQQRVCIARCLAIEPEVILM 203
Cdd:COG4987 423 TTLRENLRLA-------RPDATDEELWAALERVGLGDwlaALPDGLDTwlgeGGRRLSGGERRRLALARALLRDAPILLL 495
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 580041203 204 DEPTSALDPISTLRV-EELVQELKEKyTIIMVTHNMQQAARV 244
Cdd:COG4987 496 DEPTEGLDAATEQALlADLLEALAGR-TVLLITHRLAGLERM 536
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
40-271 |
1.87e-36 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 129.77 E-value: 1.87e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILYRDQDIFDQKYSKEqlrtNV 119
Cdd:cd03296 6 RNVSKRFGDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLER-----PDSGTILFGGEDATDVPVQER----NV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 120 GMVFQQPNPFPK-SIYDNITYGPKIHGIKNKKVLDEIVEK--SLRGAAIWDELKDRLHTNaysLSGGQQQRVCIARCLAI 196
Cdd:cd03296 77 GFVFQHYALFRHmTVFDNVAFGLRVKPRSERPPEAEIRAKvhELLKLVQLDWLADRYPAQ---LSGGQRQRVALARALAV 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 197 EPEVILMDEPTSALDpiSTLRvEEL---VQELKEK--YTIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNPSN 271
Cdd:cd03296 154 EPKVLLLDEPFGALD--AKVR-KELrrwLRRLHDElhVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGTPDEVYDHPAS 230
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
46-254 |
4.87e-36 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 127.76 E-value: 4.87e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 46 YGENH-ALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILYRDQDIfdqkySKEQLRTNVGMVFQ 124
Cdd:cd03226 9 YKKGTeILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIK-----ESSGSILLNGKPI-----KAKERRKSIGYVMQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 125 QPNP--FPKSIYDNITYGPKIHGIKNkkvldEIVEKSLRGAAIWDeLKDRlhtNAYSLSGGQQQRVCIARCLAIEPEVIL 202
Cdd:cd03226 79 DVDYqlFTDSVREELLLGLKELDAGN-----EQAETVLKDLDLYA-LKER---HPLSLSGGQKQRLAIAAALLSGKDLLI 149
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 580041203 203 MDEPTSALDPISTLRVEELVQEL-KEKYTIIMVTHNMQQAARVSDKTAFFLNG 254
Cdd:cd03226 150 FDEPTSGLDYKNMERVGELIRELaAQGKAVIVITHDYEFLAKVCDRVLLLANG 202
|
|
| cbiO |
PRK13649 |
energy-coupling factor transporter ATPase; |
48-246 |
5.16e-36 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 129.86 E-value: 5.16e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 48 ENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMveLVPsvkTAGKILYRDQDIFDQKYSKE--QLRTNVGMVFQQ 125
Cdd:PRK13649 19 EGRALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGL--HVP---TQGSVRVDDTLITSTSKNKDikQIRKKVGLVFQF 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 126 PNP--FPKSIYDNITYGPKIHGIkNKKVLDEIVEKSLRGAAIWDELKDRlhtNAYSLSGGQQQRVCIARCLAIEPEVILM 203
Cdd:PRK13649 94 PESqlFEETVLKDVAFGPQNFGV-SQEEAEALAREKLALVGISESLFEK---NPFELSGGQMRRVAIAGILAMEPKILVL 169
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 580041203 204 DEPTSALDPISTLRVEELVQELKEK-YTIIMVTHNMQQAARVSD 246
Cdd:PRK13649 170 DEPTAGLDPKGRKELMTLFKKLHQSgMTIVLVTHLMDDVANYAD 213
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
39-256 |
2.72e-35 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 127.44 E-value: 2.72e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 39 TQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMveLVPsvkTAGKILYRDQDIfdQKYSKEQLRTN 118
Cdd:PRK11231 5 TENLTVGYGTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARL--LTP---QSGTVFLGDKPI--SMLSSRQLARR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 119 VGMVFQQPnPFPK--SIYDNITYGPKIH----GIKNKKvlDE-IVEKSLRGAAIwDELKDRLHTnaySLSGGQQQRVCIA 191
Cdd:PRK11231 78 LALLPQHH-LTPEgiTVRELVAYGRSPWlslwGRLSAE--DNaRVNQAMEQTRI-NHLADRRLT---DLSGGQRQRAFLA 150
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 580041203 192 RCLAIEPEVILMDEPTSALDpISTlRVE--ELVQELKEK-YTIIMVTHNMQQAARVSDKTAFFLNGYV 256
Cdd:PRK11231 151 MVLAQDTPVVLLDEPTTYLD-INH-QVElmRLMRELNTQgKTVVTVLHDLNQASRYCDHLVVLANGHV 216
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
34-238 |
3.17e-35 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 128.04 E-value: 3.17e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 34 SVIYSTQNLDLWYGE-NHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMveLVPSvktAGKILYRDQDIfdqKYSK 112
Cdd:PRK13636 3 DYILKVEELNYNYSDgTHALKGININIKKGEVTAILGGNGAGKSTLFQNLNGI--LKPS---SGRILFDGKPI---DYSR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 113 E---QLRTNVGMVFQQPNP--FPKSIYDNITYGPKIHGIKNKKVlDEIVEKSLRGAAIwDELKDRlhtNAYSLSGGQQQR 187
Cdd:PRK13636 75 KglmKLRESVGMVFQDPDNqlFSASVYQDVSFGAVNLKLPEDEV-RKRVDNALKRTGI-EHLKDK---PTHCLSFGQKKR 149
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 580041203 188 VCIARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEKY--TIIMVTHNM 238
Cdd:PRK13636 150 VAIAGVLVMEPKVLVLDEPTAGLDPMGVSEIMKLLVEMQKELglTIIIATHDI 202
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
36-267 |
3.36e-35 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 127.82 E-value: 3.36e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 36 IYSTQNLDLWYGEN--HALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMveLVP---SVKTAGKILyRDQDIFDqky 110
Cdd:PRK13635 5 IIRVEHISFRYPDAatYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGL--LLPeagTITVGGMVL-SEETVWD--- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 111 skeqLRTNVGMVFQQP-NPFPKS-IYDNITYGPKIHGIKNkkvlDEIVEKsLRGAAIWDELKDRLHTNAYSLSGGQQQRV 188
Cdd:PRK13635 79 ----VRRQVGMVFQNPdNQFVGAtVQDDVAFGLENIGVPR----EEMVER-VDQALRQVGMEDFLNREPHRLSGGQKQRV 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 189 CIARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEK--YTIIMVTHNMQQAARvSDKTAFFLNGYVNEYDDTDKIF 266
Cdd:PRK13635 150 AIAGVLALQPDIIILDEATSMLDPRGRREVLETVRQLKEQkgITVLSITHDLDEAAQ-ADRVIVMNKGEILEEGTPEEIF 228
|
.
gi 580041203 267 S 267
Cdd:PRK13635 229 K 229
|
|
| AppF |
COG4608 |
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ... |
50-269 |
6.95e-35 |
|
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443658 [Multi-domain] Cd Length: 329 Bit Score: 127.93 E-value: 6.95e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 50 HALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILYRDQDIFdqKYSKEQLRT---NVGMVFQQP 126
Cdd:COG4608 32 KAVDGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEE-----PTSGEILFDGQDIT--GLSGRELRPlrrRMQMVFQDP 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 127 ----NPfPKSIYDNITYGPKIHGIKNKKVLDEIVEKSLR--GaaiwdeLkDRLHTNAYS--LSGGQQQRVCIARCLAIEP 198
Cdd:COG4608 105 yaslNP-RMTVGDIIAEPLRIHGLASKAERRERVAELLElvG------L-RPEHADRYPheFSGGQRQRIGIARALALNP 176
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 580041203 199 EVILMDEPTSALDpIStlrVE----ELVQELKEKY--TIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNP 269
Cdd:COG4608 177 KLIVCDEPVSALD-VS---IQaqvlNLLEDLQDELglTYLFISHDLSVVRHISDRVAVMYLGKIVEIAPRDELYARP 249
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
29-268 |
1.16e-34 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 126.26 E-value: 1.16e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 29 DTNSHSVIySTQNLDLWYG--ENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILyrdqdIF 106
Cdd:PRK13632 1 IKNKSVMI-KVENVSFSYPnsENNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLK-----PQSGEIK-----ID 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 107 DQKYSKE---QLRTNVGMVFQQP-NPF-PKSIYDNITYGpkihgIKNKKV----LDEIVEKSLRGAAIWDELKDRLHtna 177
Cdd:PRK13632 70 GITISKEnlkEIRKKIGIIFQNPdNQFiGATVEDDIAFG-----LENKKVppkkMKDIIDDLAKKVGMEDYLDKEPQ--- 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 178 ySLSGGQQQRVCIARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEK--YTIIMVTHNMQQAARvSDKTAFFLNGY 255
Cdd:PRK13632 142 -NLSGGQKQRVAIASVLALNPEIIIFDESTSMLDPKGKREIKKIMVDLRKTrkKTLISITHDMDEAIL-ADKVIVFSEGK 219
|
250
....*....|...
gi 580041203 256 VNEYDDTDKIFSN 268
Cdd:PRK13632 220 LIAQGKPKEILNN 232
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
41-236 |
1.48e-34 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 124.65 E-value: 1.48e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 41 NLDLWYGENH-ALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILYRDQDIfdQKYSKEQLRTNV 119
Cdd:cd03254 7 NVNFSYDEKKpVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYD-----PQKGQILIDGIDI--RDISRKSLRSMI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 120 GMVFQQPNPFPKSIYDNITYGpkihgikNKKVLDEIVEKSLRGAAIWDE---LKDRLHT----NAYSLSGGQQQRVCIAR 192
Cdd:cd03254 80 GVVLQDTFLFSGTIMENIRLG-------RPNATDEEVIEAAKEAGAHDFimkLPNGYDTvlgeNGGNLSQGERQLLAIAR 152
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 580041203 193 CLAIEPEVILMDEPTSALDPISTLRVEELVQELKEKYTIIMVTH 236
Cdd:cd03254 153 AMLRDPKILILDEATSNIDTETEKLIQEALEKLMKGRTSIIIAH 196
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
40-236 |
4.04e-34 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 123.49 E-value: 4.04e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYG--ENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELvpsvkTAGKILYRDQDIFDqkYSKEQLRT 117
Cdd:cd03251 4 KNVTFRYPgdGPPVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDV-----DSGRILIDGHDVRD--YTLASLRR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 118 NVGMVFQQPNPFPKSIYDNITYGpkihgikNKKVLDEIVEKSLRGAAIWD---ELKDRLHT----NAYSLSGGQQQRVCI 190
Cdd:cd03251 77 QIGLVSQDVFLFNDTVAENIAYG-------RPGATREEVEEAARAANAHEfimELPEGYDTvigeRGVKLSGGQRQRIAI 149
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 580041203 191 ARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEKYTIIMVTH 236
Cdd:cd03251 150 ARALLKDPPILILDEATSALDTESERLVQAALERLMKNRTTFVIAH 195
|
|
| cbiO |
PRK13641 |
energy-coupling factor transporter ATPase; |
48-269 |
5.11e-34 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 124.94 E-value: 5.11e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 48 ENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMveLVPSvktAGKILYRDQDIFDQKYSK--EQLRTNVGMVFQQ 125
Cdd:PRK13641 19 EKKGLDNISFELEEGSFVALVGHTGSGKSTLMQHFNAL--LKPS---SGTITIAGYHITPETGNKnlKKLRKKVSLVFQF 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 126 PNP--FPKSIYDNITYGPKIHGIKNKKVLDEIVeKSLRGAAIWDELKDRlhtNAYSLSGGQQQRVCIARCLAIEPEVILM 203
Cdd:PRK13641 94 PEAqlFENTVLKDVEFGPKNFGFSEDEAKEKAL-KWLKKVGLSEDLISK---SPFELSGGQMRRVAIAGVMAYEPEILCL 169
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 580041203 204 DEPTSALDPISTLRVEELVQEL-KEKYTIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNP 269
Cdd:PRK13641 170 DEPAAGLDPEGRKEMMQLFKDYqKAGHTVILVTHNMDDVAEYADDVLVLEHGKLIKHASPKEIFSDK 236
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
54-254 |
8.71e-34 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 122.40 E-value: 8.71e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 54 NINLDIyENQITAIIGPSGCGKSTYIKTLNRMVELvpsvkTAGKILYRDQDIFDqkySKEQL-----RTNVGMVFQQPNP 128
Cdd:cd03297 16 KIDFDL-NEEVTGIFGASGAGKSTLLRCIAGLEKP-----DGGTIVLNGTVLFD---SRKKInlppqQRKIGLVFQQYAL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 129 FPK-SIYDNITYGPKIHGIKNKKVLdeiVEKSLRGAAIwDELKDRlhtNAYSLSGGQQQRVCIARCLAIEPEVILMDEPT 207
Cdd:cd03297 87 FPHlNVRENLAFGLKRKRNREDRIS---VDELLDLLGL-DHLLNR---YPAQLSGGEKQRVALARALAAQPELLLLDEPF 159
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 580041203 208 SALDPISTLRVEELVQELKEKYTI--IMVTHNMQQAARVSDKTAFFLNG 254
Cdd:cd03297 160 SALDRALRLQLLPELKQIKKNLNIpvIFVTHDLSEAEYLADRIVVMEDG 208
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
35-269 |
1.06e-33 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 128.26 E-value: 1.06e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 35 VIYSTQNLDLWY-----------GENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRmveLVPSvktAGKILYRDQ 103
Cdd:COG4172 274 PLLEARDLKVWFpikrglfrrtvGHVKAVDGVSLTLRRGETLGLVGESGSGKSTLGLALLR---LIPS---EGEIRFDGQ 347
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 104 DIfdQKYSKEQ---LRTNVGMVFQqpNPF----PK-SIYDNITYGPKIHGIK-NKKVLDEIVEKSLRGAAIWDELKDRlh 174
Cdd:COG4172 348 DL--DGLSRRAlrpLRRRMQVVFQ--DPFgslsPRmTVGQIIAEGLRVHGPGlSAAERRARVAEALEEVGLDPAARHR-- 421
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 175 tnaY--SLSGGQQQRVCIARCLAIEPEVILMDEPTSALDpiSTLRVE--ELVQELKEKY--TIIMVTHNMQQAARVSDKT 248
Cdd:COG4172 422 ---YphEFSGGQRQRIAIARALILEPKLLVLDEPTSALD--VSVQAQilDLLRDLQREHglAYLFISHDLAVVRALAHRV 496
|
250 260
....*....|....*....|.
gi 580041203 249 AFFLNGYVNEYDDTDKIFSNP 269
Cdd:COG4172 497 MVMKDGKVVEQGPTEQVFDAP 517
|
|
| PRK11000 |
PRK11000 |
maltose/maltodextrin ABC transporter ATP-binding protein MalK; |
46-272 |
2.46e-33 |
|
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 124.76 E-value: 2.46e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 46 YGENHALQNINLDIYENQITAIIGPSGCGKSTyiktLNRMVELVPSVkTAGKILYRDQDIFDQKYSKEqlrtNVGMVFQQ 125
Cdd:PRK11000 13 YGDVVISKDINLDIHEGEFVVFVGPSGCGKST----LLRMIAGLEDI-TSGDLFIGEKRMNDVPPAER----GVGMVFQS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 126 PNPFPK-SIYDNITYGPKIHGIKnKKVLDEIVEKSlrgAAIWdELKDRLHTNAYSLSGGQQQRVCIARCLAIEPEVILMD 204
Cdd:PRK11000 84 YALYPHlSVAENMSFGLKLAGAK-KEEINQRVNQV---AEVL-QLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFLLD 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 580041203 205 EPTSALDpiSTLRVE------ELVQELKEkyTIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNPSNK 272
Cdd:PRK11000 159 EPLSNLD--AALRVQmrieisRLHKRLGR--TMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKPLELYHYPANR 228
|
|
| PRK13651 |
PRK13651 |
cobalt transporter ATP-binding subunit; Provisional |
51-268 |
3.74e-33 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 122.89 E-value: 3.74e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 51 ALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMveLVPsvkTAGKILYRDQDIFDQKYSKE----------------- 113
Cdd:PRK13651 22 ALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNAL--LLP---DTGTIEWIFKDEKNKKKTKEkekvleklviqktrfkk 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 114 -----QLRTNVGMVFQ--QPNPFPKSIYDNITYGPKIHGIKNKkvldEIVEKSLRGAAIWDELKDRLHTNAYSLSGGQQQ 186
Cdd:PRK13651 97 ikkikEIRRRVGVVFQfaEYQLFEQTIEKDIIFGPVSMGVSKE----EAKKRAAKYIELVGLDESYLQRSPFELSGGQKR 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 187 RVCIARCLAIEPEVILMDEPTSALDPISTLRVEELVQEL-KEKYTIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKI 265
Cdd:PRK13651 173 RVALAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNLnKQGKTIILVTHDLDNVLEWTKRTIFFKDGKIIKDGDTYDI 252
|
...
gi 580041203 266 FSN 268
Cdd:PRK13651 253 LSD 255
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
39-254 |
5.75e-33 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 120.17 E-value: 5.75e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 39 TQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMveLVPsvkTAGKILYRDQDIFdqKYSKEqLRTN 118
Cdd:cd03265 3 VENLVKKYGDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTL--LKP---TSGRATVAGHDVV--REPRE-VRRR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 119 VGMVFQQPNPFPK-SIYDNITYGPKIHGIKNKKvLDEIVEKSLRGAAIWdELKDRLhtnAYSLSGGQQQRVCIARCLAIE 197
Cdd:cd03265 75 IGIVFQDLSVDDElTGWENLYIHARLYGVPGAE-RRERIDELLDFVGLL-EAADRL---VKTYSGGMRRRLEIARSLVHR 149
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 580041203 198 PEVILMDEPTSALDPISTLRVEELVQELKEKY--TIIMVTHNMQQAARVSDKTAFFLNG 254
Cdd:cd03265 150 PEVLFLDEPTIGLDPQTRAHVWEYIEKLKEEFgmTILLTTHYMEEAEQLCDRVAIIDHG 208
|
|
| cbiO |
PRK13647 |
cobalt transporter ATP-binding subunit; Provisional |
36-256 |
5.90e-33 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 121.77 E-value: 5.90e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 36 IYSTQNLDLWYGE-NHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRmVELVP--SVKTAGKILyrdqdifDQKYSK 112
Cdd:PRK13647 4 IIEVEDLHFRYKDgTKALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNG-IYLPQrgRVKVMGREV-------NAENEK 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 113 EqLRTNVGMVFQQPNP--FPKSIYDNITYGPKIHGIKNKKVlDEIVEKSLRGAAIWDeLKDRlhtNAYSLSGGQQQRVCI 190
Cdd:PRK13647 76 W-VRSKVGLVFQDPDDqvFSSTVWDDVAFGPVNMGLDKDEV-ERRVEEALKAVRMWD-FRDK---PPYHLSYGQKKRVAI 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 580041203 191 ARCLAIEPEVILMDEPTSALDPISTLRVEELVQEL-KEKYTIIMVTHNMQQAARVSDKTAFFLNGYV 256
Cdd:PRK13647 150 AGVLAMDPDVIVLDEPMAYLDPRGQETLMEILDRLhNQGKTVIVATHDVDLAAEWADQVIVLKEGRV 216
|
|
| PRK13633 |
PRK13633 |
energy-coupling factor transporter ATPase; |
48-242 |
6.15e-33 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 121.73 E-value: 6.15e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 48 ENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMveLVPsvkTAGKILYRDQDIFDQKYSKEqLRTNVGMVFQQP- 126
Cdd:PRK13633 22 EKLALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNAL--LIP---SEGKVYVDGLDTSDEENLWD-IRNKAGMVFQNPd 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 127 NPFPKSIYD-NITYGPKIHGIKNKKVlDEIVEKSLRGAAIWDELKDRLHTnaysLSGGQQQRVCIARCLAIEPEVILMDE 205
Cdd:PRK13633 96 NQIVATIVEeDVAFGPENLGIPPEEI-RERVDESLKKVGMYEYRRHAPHL----LSGGQKQRVAIAGILAMRPECIIFDE 170
|
170 180 190
....*....|....*....|....*....|....*....
gi 580041203 206 PTSALDPISTLRVEELVQELKEKY--TIIMVTHNMQQAA 242
Cdd:PRK13633 171 PTAMLDPSGRREVVNTIKELNKKYgiTIILITHYMEEAV 209
|
|
| PRK10070 |
PRK10070 |
proline/glycine betaine ABC transporter ATP-binding protein ProV; |
47-280 |
6.55e-33 |
|
proline/glycine betaine ABC transporter ATP-binding protein ProV;
Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 124.38 E-value: 6.55e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 47 GENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILYRDQDI--FDQKYSKEQLRTNVGMVFQ 124
Cdd:PRK10070 39 GLSLGVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIE-----PTRGQVLIDGVDIakISDAELREVRRKKIAMVFQ 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 125 QPNPFPK-SIYDNITYGPKIHGI----KNKKVLDEIVEKSLRGAAiwdelkdrlHTNAYSLSGGQQQRVCIARCLAIEPE 199
Cdd:PRK10070 114 SFALMPHmTVLDNTAFGMELAGInaeeRREKALDALRQVGLENYA---------HSYPDELSGGMRQRVGLARALAINPD 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 200 VILMDEPTSALDP-ISTLRVEELVQ-ELKEKYTIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNPSNKKTEDY 277
Cdd:PRK10070 185 ILLMDEAFSALDPlIRTEMQDELVKlQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILNNPANDYVRTF 264
|
...
gi 580041203 278 ISG 280
Cdd:PRK10070 265 FRG 267
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
36-269 |
9.78e-33 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 121.06 E-value: 9.78e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 36 IYSTQNLDLWY-GENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMveLVPsvkTAGKILYRDQDIfdQKYSKEQ 114
Cdd:PRK13652 3 LIETRDLCYSYsGSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGI--LKP---TSGSVLIRGEPI--TKENIRE 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 115 LRTNVGMVFQQPNP--FPKSIYDNITYGPKIHGIKNKKVLDEiVEKSLRGAAIwDELKDRLhtnAYSLSGGQQQRVCIAR 192
Cdd:PRK13652 76 VRKFVGLVFQNPDDqiFSPTVEQDIAFGPINLGLDEETVAHR-VSSALHMLGL-EELRDRV---PHHLSGGEKKRVAIAG 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 580041203 193 CLAIEPEVILMDEPTSALDPISTLRVEELVQELKEKY--TIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNP 269
Cdd:PRK13652 151 VIAMEPQVLVLDEPTAGLDPQGVKELIDFLNDLPETYgmTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEIFLQP 229
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
48-238 |
1.47e-32 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 119.23 E-value: 1.47e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 48 ENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMveLVPsvkTAGKILYRDQDIfdQKYSKEQLRTNVGMVFQQPN 127
Cdd:cd03245 16 EIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGL--YKP---TSGSVLLDGTDI--RQLDPADLRRNIGYVPQDVT 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 128 PFPKSIYDNITYGpkihgikNKKVLDEIVEKSLRGAAIwDELKDRlHTNAY---------SLSGGQQQRVCIARCLAIEP 198
Cdd:cd03245 89 LFYGTLRDNITLG-------APLADDERILRAAELAGV-TDFVNK-HPNGLdlqigergrGLSGGQRQAVALARALLNDP 159
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 580041203 199 EVILMDEPTSALDPISTLRVEELVQELKEKYTIIMVTHNM 238
Cdd:cd03245 160 PILLLDEPTSAMDMNSEERLKERLRQLLGDKTLIIITHRP 199
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
25-271 |
3.25e-32 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 121.98 E-value: 3.25e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 25 KTPDDTNSHSVIYSTQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELvpsvkTAGKILYRDQD 104
Cdd:PRK09452 3 KLNKQPSSLSPLVELRGISKSFDGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETP-----DSGRIMLDGQD 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 105 IFDQKYSKEQLRTnvgmVFQQPNPFPK-SIYDNITYGpkihgIKNKKV-LDEI---VEKSLRGAAIwDELKDRlhtNAYS 179
Cdd:PRK09452 78 ITHVPAENRHVNT----VFQSYALFPHmTVFENVAFG-----LRMQKTpAAEItprVMEALRMVQL-EEFAQR---KPHQ 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 180 LSGGQQQRVCIARCLAIEPEVILMDEPTSALDpiSTLRvEELVQELKE-----KYTIIMVTHNMQQAARVSDKTAFFLNG 254
Cdd:PRK09452 145 LSGGQQQRVAIARAVVNKPKVLLLDESLSALD--YKLR-KQMQNELKAlqrklGITFVFVTHDQEEALTMSDRIVVMRDG 221
|
250
....*....|....*...
gi 580041203 255 YVnEYDDTDK-IFSNPSN 271
Cdd:PRK09452 222 RI-EQDGTPReIYEEPKN 238
|
|
| ABCC_ATM1_transporter |
cd03253 |
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ... |
52-258 |
3.55e-32 |
|
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 118.49 E-value: 3.55e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 52 LQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELvpsvkTAGKILYRDQDIfdQKYSKEQLRTNVGMVFQQPNPFPK 131
Cdd:cd03253 17 LKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDV-----SSGSILIDGQDI--REVTLDSLRRAIGVVPQDTVLFND 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 132 SIYDNITYGpkihgikNKKVLDEIVEKSLRGAAIWDELKdRLhTNAYS---------LSGGQQQRVCIARCLAIEPEVIL 202
Cdd:cd03253 90 TIGYNIRYG-------RPDATDEEVIEAAKAAQIHDKIM-RF-PDGYDtivgerglkLSGGEKQRVAIARAILKNPPILL 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 580041203 203 MDEPTSALDPISTLRVEELVQELKEKYTIIMVTHNMQQAARvSDKTAFFLNGYVNE 258
Cdd:cd03253 161 LDEATSALDTHTEREIQAALRDVSKGRTTIVIAHRLSTIVN-ADKIIVLKDGRIVE 215
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
40-269 |
5.48e-32 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 123.64 E-value: 5.48e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYG----ENHALQNINLDIYENQITAIIGPSGCGKSTyikTLNRMVELVPS--VKTAGKILYRDQDIFDQkySKE 113
Cdd:COG4172 10 EDLSVAFGqgggTVEAVKGVSFDIAAGETLALVGESGSGKSV---TALSILRLLPDpaAHPSGSILFDGQDLLGL--SER 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 114 QLRT----NVGMVFQQP----NPFpKSIYDNITYGPKIH-GIKNKKVLDEIVEkSLRGAAIwDELKDRLhtNAY--SLSG 182
Cdd:COG4172 85 ELRRirgnRIAMIFQEPmtslNPL-HTIGKQIAEVLRLHrGLSGAAARARALE-LLERVGI-PDPERRL--DAYphQLSG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 183 GQQQRVCIARCLAIEPEVILMDEPTSALDPisTLRVE--ELVQELKEKY--TIIMVTHNMQQAARVSDKTAFFLNGYVNE 258
Cdd:COG4172 160 GQRQRVMIAMALANEPDLLIADEPTTALDV--TVQAQilDLLKDLQRELgmALLLITHDLGVVRRFADRVAVMRQGEIVE 237
|
250
....*....|.
gi 580041203 259 YDDTDKIFSNP 269
Cdd:COG4172 238 QGPTAELFAAP 248
|
|
| PRK10851 |
PRK10851 |
sulfate/thiosulfate ABC transporter ATP-binding protein CysA; |
46-272 |
5.72e-32 |
|
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 120.96 E-value: 5.72e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 46 YGENHALQNINLDIYENQITAIIGPSGCGKSTyiktLNRMVELVPSvKTAGKILYRDQDIfDQKYSKEQlrtNVGMVFQQ 125
Cdd:PRK10851 12 FGRTQVLNDISLDIPSGQMVALLGPSGSGKTT----LLRIIAGLEH-QTSGHIRFHGTDV-SRLHARDR---KVGFVFQH 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 126 PNPFPK-SIYDNITYG---------PKIHGIKnKKV--LDEIVEKSlrgaaiwdELKDRLHTNaysLSGGQQQRVCIARC 193
Cdd:PRK10851 83 YALFRHmTVFDNIAFGltvlprrerPNAAAIK-AKVtqLLEMVQLA--------HLADRYPAQ---LSGGQKQRVALARA 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 194 LAIEPEVILMDEPTSALDpiSTLRVE------ELVQELkeKYTIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFS 267
Cdd:PRK10851 151 LAVEPQILLLDEPFGALD--AQVRKElrrwlrQLHEEL--KFTSVFVTHDQEEAMEVADRVVVMSQGNIEQAGTPDQVWR 226
|
....*
gi 580041203 268 NPSNK 272
Cdd:PRK10851 227 EPATR 231
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
38-247 |
7.31e-32 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 115.60 E-value: 7.31e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 38 STQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILYRDQDIfDQKYSKEQLRT 117
Cdd:cd03216 2 ELRGITKRFGGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYK-----PDSGEILVDGKEV-SFASPRDARRA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 118 NVGMVFQqpnpfpksiydnitygpkihgiknkkvldeivekslrgaaiwdelkdrlhtnaysLSGGQQQRVCIARCLAIE 197
Cdd:cd03216 76 GIAMVYQ-------------------------------------------------------LSVGERQMVEIARALARN 100
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 580041203 198 PEVILMDEPTSALDPISTLRVEELVQELKEK-YTIIMVTHNMQQAARVSDK 247
Cdd:cd03216 101 ARLLILDEPTAALTPAEVERLFKVIRRLRAQgVAVIFISHRLDEVFEIADR 151
|
|
| FtsE |
TIGR02673 |
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC ... |
50-248 |
9.90e-32 |
|
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC transporter ATP-binding protein family. This protein, and its permease partner FtsX, localize to the division site. In a number of species, the ftsEX gene pair is located next to FtsY, the signal recognition particle-docking protein. [Cellular processes, Cell division]
Pssm-ID: 131721 [Multi-domain] Cd Length: 214 Bit Score: 116.96 E-value: 9.90e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 50 HALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMveLVPsvkTAGKILYRDQDIFDQKYSK-EQLRTNVGMVFQQPNP 128
Cdd:TIGR02673 16 AALHDVSLHIRKGEFLFLTGPSGAGKTTLLKLLYGA--LTP---SRGQVRIAGEDVNRLRGRQlPLLRRRIGVVFQDFRL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 129 FP-KSIYDNITYGPKIHGIKNKKVlDEIVEKSLRgaaiWDELKDRLHTNAYSLSGGQQQRVCIARCLAIEPEVILMDEPT 207
Cdd:TIGR02673 91 LPdRTVYENVALPLEVRGKKEREI-QRRVGAALR----QVGLEHKADAFPEQLSGGEQQRVAIARAIVNSPPLLLADEPT 165
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 580041203 208 SALDPISTLRVEELVQEL-KEKYTIIMVTHNMQQAARVSDKT 248
Cdd:TIGR02673 166 GNLDPDLSERILDLLKRLnKRGTTVIVATHDLSLVDRVAHRV 207
|
|
| TauB |
COG4525 |
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism]; |
40-241 |
1.32e-31 |
|
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443596 [Multi-domain] Cd Length: 262 Bit Score: 117.66 E-value: 1.32e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGEN----HALQNINLDIYENQITAIIGPSGCGKSTYiktLNRMVELVPSvkTAGKILYRDQDIfdQKYSKEQl 115
Cdd:COG4525 7 RHVSVRYPGGgqpqPALQDVSLTIESGEFVVALGASGCGKTTL---LNLIAGFLAP--SSGEITLDGVPV--TGPGADR- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 116 rtnvGMVFQQPNPFP-KSIYDNITYGPKIHGIkNKKVLDEIVEKSLR--GaaiwdeLKDRLHTNAYSLSGGQQQRVCIAR 192
Cdd:COG4525 79 ----GVVFQKDALLPwLNVLDNVAFGLRLRGV-PKAERRARAEELLAlvG------LADFARRRIWQLSGGMRQRVGIAR 147
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 580041203 193 CLAIEPEVILMDEPTSALDPISTLRVEELVQELKEKY--TIIMVTHNMQQA 241
Cdd:COG4525 148 ALAADPRFLLMDEPFGALDALTREQMQELLLDVWQRTgkGVFLITHSVEEA 198
|
|
| drrA |
TIGR01188 |
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin ... |
46-249 |
1.57e-31 |
|
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other]
Pssm-ID: 130256 [Multi-domain] Cd Length: 302 Bit Score: 118.65 E-value: 1.57e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 46 YGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMveLVPsvkTAGKILYRDQDIFDQKyskEQLRTNVGMVFQQ 125
Cdd:TIGR01188 3 YGDFKAVDGVNFKVREGEVFGFLGPNGAGKTTTIRMLTTL--LRP---TSGTARVAGYDVVREP---RKVRRSIGIVPQY 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 126 PNPFPK-SIYDNITYGPKIHGIKnKKVLDEIVEKSLRGAAIWDELKDRLHTnaysLSGGQQQRVCIARCLAIEPEVILMD 204
Cdd:TIGR01188 75 ASVDEDlTGRENLEMMGRLYGLP-KDEAEERAEELLELFELGEAADRPVGT----YSGGMRRRLDIAASLIHQPDVLFLD 149
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 580041203 205 EPTSALDPISTLRVEELVQELKE-KYTIIMVTHNMQQAARVSDKTA 249
Cdd:TIGR01188 150 EPTTGLDPRTRRAIWDYIRALKEeGVTILLTTHYMEEADKLCDRIA 195
|
|
| potA |
TIGR01187 |
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ... |
67-271 |
1.66e-31 |
|
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 162242 [Multi-domain] Cd Length: 325 Bit Score: 119.14 E-value: 1.66e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 67 IIGPSGCGKSTYIKTLNRMVELvpsvkTAGKILYRDQDIFDQKyskEQLRtNVGMVFQQPNPFPK-SIYDNITYGPKIHG 145
Cdd:TIGR01187 1 LLGPSGCGKTTLLRLLAGFEQP-----DSGSIMLDGEDVTNVP---PHLR-HINMVFQSYALFPHmTVEENVAFGLKMRK 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 146 IKNKKVlDEIVEKSLRGAAIWDELKDRLHtnaySLSGGQQQRVCIARCLAIEPEVILMDEPTSALDpiSTLRvEELVQEL 225
Cdd:TIGR01187 72 VPRAEI-KPRVLEALRLVQLEEFADRKPH----QLSGGQQQRVALARALVFKPKILLLDEPLSALD--KKLR-DQMQLEL 143
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 580041203 226 KEKY-----TIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNPSN 271
Cdd:TIGR01187 144 KTIQeqlgiTFVFVTHDQEEAMTMSDRIAIMRKGKIAQIGTPEEIYEEPAN 194
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
51-237 |
3.36e-31 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 115.58 E-value: 3.36e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 51 ALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILYRDQDIFDQKYSK-EQLRTNVGMVFQQPNPF 129
Cdd:cd03292 16 ALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEEL-----PTSGTIRVNGQDVSDLRGRAiPYLRRKIGVVFQDFRLL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 130 PK-SIYDNITYGPKIHGIKNKkvldEIVEkslRGAAIWDE--LKDRLHTNAYSLSGGQQQRVCIARCLAIEPEVILMDEP 206
Cdd:cd03292 91 PDrNVYENVAFALEVTGVPPR----EIRK---RVPAALELvgLSHKHRALPAELSGGEQQRVAIARAIVNSPTILIADEP 163
|
170 180 190
....*....|....*....|....*....|..
gi 580041203 207 TSALDPISTLRVEELVQEL-KEKYTIIMVTHN 237
Cdd:cd03292 164 TGNLDPDTTWEIMNLLKKInKAGTTVVVATHA 195
|
|
| cbiO |
TIGR01166 |
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of ... |
47-241 |
7.96e-31 |
|
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of the multisubunit cobalt transporter in bacteria and its equivalents in archaea. The model is restricted to ATP subunit that is a part of the cobalt transporter, which belongs to the ABC transporter superfamily (ATP Binding Cassette). The model excludes ATP binding subunit that are associated with other transporters belonging to ABC transporter superfamily. This superfamily includes two groups, one which catalyze the uptake of small molecules, including ions from the external milieu and the other group which is engaged in the efflux of small molecular weight compounds and ions from within the cell. Energy derived from the hydrolysis of ATP drive the both the process of uptake and efflux. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 130234 [Multi-domain] Cd Length: 190 Bit Score: 113.67 E-value: 7.96e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 47 GENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMveLVPsvkTAGKILYRDQDIfdqKYSKEQL---RTNVGMVF 123
Cdd:TIGR01166 3 GGPEVLKGLNFAAERGEVLALLGANGAGKSTLLLHLNGL--LRP---QSGAVLIDGEPL---DYSRKGLlerRQRVGLVF 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 124 QQPNP--FPKSIYDNITYGPKIHGIKNKKVlDEIVEKSLRGAAIwDELKDRLhtnAYSLSGGQQQRVCIARCLAIEPEVI 201
Cdd:TIGR01166 75 QDPDDqlFAADVDQDVAFGPLNLGLSEAEV-ERRVREALTAVGA-SGLRERP---THCLSGGEKKRVAIAGAVAMRPDVL 149
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 580041203 202 LMDEPTSALDPISTLRVEELVQELKEK-YTIIMVTHNMQQA 241
Cdd:TIGR01166 150 LLDEPTAGLDPAGREQMLAILRRLRAEgMTVVISTHDVDLA 190
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
51-269 |
9.51e-31 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 115.95 E-value: 9.51e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 51 ALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILYRDQDIfdqKYSKEQL---RTNVGMVFQQPN 127
Cdd:PRK13639 17 ALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILK-----PTSGEVLIKGEPI---KYDKKSLlevRKTVGIVFQNPD 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 128 P--FPKSIYDNITYGPKIHGIKNKKVlDEIVEKSLRGAAIWDELKDRLHtnaySLSGGQQQRVCIARCLAIEPEVILMDE 205
Cdd:PRK13639 89 DqlFAPTVEEDVAFGPLNLGLSKEEV-EKRVKEALKAVGMEGFENKPPH----HLSGGQKKRVAIAGILAMKPEIIVLDE 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 580041203 206 PTSALDPISTLRVEELVQEL-KEKYTIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNP 269
Cdd:PRK13639 164 PTSGLDPMGASQIMKLLYDLnKEGITIIISTHDVDLVPVYADKVYVMSDGKIIKEGTPKEVFSDI 228
|
|
| cbiO |
PRK13631 |
cobalt transporter ATP-binding subunit; Provisional |
32-269 |
1.44e-30 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 116.49 E-value: 1.44e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 32 SHSVIYSTQNLDLWYGENH-----ALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVE------LVPSVKTAGKILY 100
Cdd:PRK13631 17 SDDIILRVKNLYCVFDEKQenelvALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKskygtiQVGDIYIGDKKNN 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 101 RDQDIF-DQKYSK--EQLRTNVGMVFQQP--NPFPKSIYDNITYGPKIHGIKnKKVLDEIVEKSLRGAAIWDELKDRlht 175
Cdd:PRK13631 97 HELITNpYSKKIKnfKELRRRVSMVFQFPeyQLFKDTIEKDIMFGPVALGVK-KSEAKKLAKFYLNKMGLDDSYLER--- 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 176 NAYSLSGGQQQRVCIARCLAIEPEVILMDEPTSALDPISTLRVEELVQELK-EKYTIIMVTHNMQQAARVSDKTAFFLNG 254
Cdd:PRK13631 173 SPFGLSGGQKRRVAIAGILAIQPEILIFDEPTAGLDPKGEHEMMQLILDAKaNNKTVFVITHTMEHVLEVADEVIVMDKG 252
|
250
....*....|....*
gi 580041203 255 YVNEYDDTDKIFSNP 269
Cdd:PRK13631 253 KILKTGTPYEIFTDQ 267
|
|
| LPS_export_lptB |
TIGR04406 |
LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ... |
40-273 |
1.59e-30 |
|
LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ATP-binding cassette protein of an ABC transporter involved in lipopolysaccharide export. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]
Pssm-ID: 275199 [Multi-domain] Cd Length: 239 Bit Score: 114.29 E-value: 1.59e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTyikTLNRMVELVPSvkTAGKILYRDQDIFDQKYsKEQLRTNV 119
Cdd:TIGR04406 5 ENLIKSYKKRKVVNDVSLSVKSGEIVGLLGPNGAGKTT---SFYMIVGLVRP--DAGKILIDGQDITHLPM-HERARLGI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 120 GMVFQQPNPFPK-SIYDNItygpkihgiknKKVLdEIVEKSLRGA--AIWDELKDRLH------TNAYSLSGGQQQRVCI 190
Cdd:TIGR04406 79 GYLPQEASIFRKlTVEENI-----------MAVL-EIRKDLDRAEreERLEALLEEFQishlrdNKAMSLSGGERRRVEI 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 191 ARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEKYTIIMVT-HNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNP 269
Cdd:TIGR04406 147 ARALATNPKFILLDEPFAGVDPIAVGDIKKIIKHLKERGIGVLITdHNVRETLDICDRAYIISDGKVLAEGTPAEIVANE 226
|
....
gi 580041203 270 SNKK 273
Cdd:TIGR04406 227 KVRR 230
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
41-236 |
1.67e-30 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 119.31 E-value: 1.67e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 41 NLDLWY-GENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILYRDQDIFDqkYSKEQLRTNV 119
Cdd:TIGR02857 326 GVSVAYpGRRPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVD-----PTEGSIAVNGVPLAD--ADADSWRDQI 398
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 120 GMVFQQPNPFPKSIYDNITYGpkihgikNKKVLDEIVEKSLRGAAIWDELKDR---LHT----NAYSLSGGQQQRVCIAR 192
Cdd:TIGR02857 399 AWVPQHPFLFAGTIAENIRLA-------RPDASDAEIREALERAGLDEFVAALpqgLDTpigeGGAGLSGGQAQRLALAR 471
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 580041203 193 CLAIEPEVILMDEPTSALDPISTLRVEELVQELKEKYTIIMVTH 236
Cdd:TIGR02857 472 AFLRDAPLLLLDEPTAHLDAETEAEVLEALRALAQGRTVLLVTH 515
|
|
| cbiO |
PRK13648 |
cobalt transporter ATP-binding subunit; Provisional |
51-242 |
2.51e-30 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 114.85 E-value: 2.51e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 51 ALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELvpsvkTAGKILYRDQDIFDQkySKEQLRTNVGMVFQQP-NPF 129
Cdd:PRK13648 24 TLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKV-----KSGEIFYNNQAITDD--NFEKLRKHIGIVFQNPdNQF 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 130 PKSI--YDnITYGPKIHGIKNKKvLDEIVEKSLRGAaiwdELKDRLHTNAYSLSGGQQQRVCIARCLAIEPEVILMDEPT 207
Cdd:PRK13648 97 VGSIvkYD-VAFGLENHAVPYDE-MHRRVSEALKQV----DMLERADYEPNALSGGQKQRVAIAGVLALNPSVIILDEAT 170
|
170 180 190
....*....|....*....|....*....|....*..
gi 580041203 208 SALDPISTLRVEELVQELKEKY--TIIMVTHNMQQAA 242
Cdd:PRK13648 171 SMLDPDARQNLLDLVRKVKSEHniTIISITHDLSEAM 207
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
41-254 |
3.33e-30 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 112.67 E-value: 3.33e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 41 NLDLWYGENHALQNINLDIyENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILYRDQDIFDQKyskEQLRTNVG 120
Cdd:cd03264 5 NLTKRYGKKRALDGVSLTL-GPGMYGLLGPNGAGKTTLMRILATLTP-----PSSGTIRIDGQDVLKQP---QKLRRRIG 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 121 MVFQQPNPFPK-SIYDNITYGPKIHGIKNKKVlDEIVEKSLRGAAIWDELKDRLHtnaySLSGGQQQRVCIARCLAIEPE 199
Cdd:cd03264 76 YLPQEFGVYPNfTVREFLDYIAWLKGIPSKEV-KARVDEVLELVNLGDRAKKKIG----SLSGGMRRRVGIAQALVGDPS 150
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 580041203 200 VILMDEPTSALDPISTLRVEELVQELKEKYTIIMVTHNMQQAARVSDKTAFFLNG 254
Cdd:cd03264 151 ILIVDEPTAGLDPEERIRFRNLLSELGEDRIVILSTHIVEDVESLCNQVAVLNKG 205
|
|
| fbpC |
PRK11432 |
ferric ABC transporter ATP-binding protein; |
46-246 |
7.91e-30 |
|
ferric ABC transporter ATP-binding protein;
Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 115.20 E-value: 7.91e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 46 YGENHALQNINLDIYENQITAIIGPSGCGKSTYIKtlnrmveLVPSVK--TAGKILYRDQDIFDqkySKEQLRtNVGMVF 123
Cdd:PRK11432 16 FGSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLR-------LVAGLEkpTEGQIFIDGEDVTH---RSIQQR-DICMVF 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 124 QQPNPFPK-SIYDNITYGPKIHGIKNkkvlDEIVEKSLRGAAIWD--ELKDRLhtnAYSLSGGQQQRVCIARCLAIEPEV 200
Cdd:PRK11432 85 QSYALFPHmSLGENVGYGLKMLGVPK----EERKQRVKEALELVDlaGFEDRY---VDQISGGQQQRVALARALILKPKV 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 580041203 201 ILMDEPTSALDpiSTLR--VEELVQELKEKYTI--IMVTHNMQQAARVSD 246
Cdd:PRK11432 158 LLFDEPLSNLD--ANLRrsMREKIRELQQQFNItsLYVTHDQSEAFAVSD 205
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
43-256 |
1.09e-29 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 111.43 E-value: 1.09e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 43 DLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYiktLNrmveLVPSVKTA--GKILYRDQDIfdqkYSKEQLRTNVG 120
Cdd:cd03298 5 KIRFSYGEQPMHFDLTFAQGEITAIVGPSGSGKSTL---LN----LIAGFETPqsGRVLINGVDV----TAAPPADRPVS 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 121 MVFQQPNPFPK-SIYDNITYGpKIHGIKNKKVLDEIVEKSLRGAAIwDELKDRLhtnAYSLSGGQQQRVCIARCLAIEPE 199
Cdd:cd03298 74 MLFQENNLFAHlTVEQNVGLG-LSPGLKLTAEDRQAIEVALARVGL-AGLEKRL---PGELSGGERQRVALARVLVRDKP 148
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 580041203 200 VILMDEPTSALDPISTLRVEELVQEL--KEKYTIIMVTHNMQQAARVSDKTAFFLNGYV 256
Cdd:cd03298 149 VLLLDEPFAALDPALRAEMLDLVLDLhaETKMTVLMVTHQPEDAKRLAQRVVFLDNGRI 207
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
46-246 |
1.30e-29 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 116.66 E-value: 1.30e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 46 YGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILYRDQDIfDQKYSKEQLRTNVGMVFQQ 125
Cdd:COG1129 14 FGGVKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQ-----PDSGEILLDGEPV-RFRSPRDAQAAGIAIIHQE 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 126 PNPFPK-SIYDNITYGpkiHGIKNKKVLDEiveKSLRGAAiwDELKDRL------HTNAYSLSGGQQQRVCIARCLAIEP 198
Cdd:COG1129 88 LNLVPNlSVAENIFLG---REPRRGGLIDW---RAMRRRA--RELLARLgldidpDTPVGDLSVAQQQLVEIARALSRDA 159
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 580041203 199 EVILMDEPTSALDPISTLRVEELVQELKEK-YTIIMVTHNMQQAARVSD 246
Cdd:COG1129 160 RVLILDEPTASLTEREVERLFRIIRRLKAQgVAIIYISHRLDEVFEIAD 208
|
|
| cbiO |
PRK13645 |
energy-coupling factor transporter ATPase; |
48-268 |
1.46e-29 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 113.18 E-value: 1.46e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 48 ENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVelvpsVKTAGKILYRDQDI-FDQKYSKE--QLRTNVGMVFQ 124
Cdd:PRK13645 23 EFKALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLI-----ISETGQTIVGDYAIpANLKKIKEvkRLRKEIGLVFQ 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 125 QP--NPFPKSIYDNITYGPkIHGIKNKKVLDEIVEKSLRGAAIWDELKDRlhtNAYSLSGGQQQRVCIARCLAIEPEVIL 202
Cdd:PRK13645 98 FPeyQLFQETIEKDIAFGP-VNLGENKQEAYKKVPELLKLVQLPEDYVKR---SPFELSGGQKRRVALAGIIAMDGNTLV 173
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 580041203 203 MDEPTSALDPISTLRVEELVQELKEKYT--IIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSN 268
Cdd:PRK13645 174 LDEPTGGLDPKGEEDFINLFERLNKEYKkrIIMVTHNMDQVLRIADEVIVMHEGKVISIGSPFEIFSN 241
|
|
| L_ocin_972_ABC |
TIGR03608 |
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly ... |
40-244 |
1.62e-29 |
|
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly wide distribution consists of a polypeptide related to the lactococcin 972 (see TIGR01653) and multiple-membrane-spanning putative immunity protein (see TIGR01654). This model represents a small clade within the ABC transporters that regularly are found adjacent to these bacteriocin system gene pairs and are likely serve as export proteins. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 188353 [Multi-domain] Cd Length: 206 Bit Score: 110.78 E-value: 1.62e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYiktLNRMVELVPsvKTAGKILYRDQDIFDQKYSKEQ--LRT 117
Cdd:TIGR03608 2 KNISKKFGDKVILDDLNLTIEKGKMYAIIGESGSGKSTL---LNIIGLLEK--FDSGQVYLNGQETPPLNSKKASkfRRE 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 118 NVGMVFQQpnpFP----KSIYDNITYGPKIHgIKNKKVLDEIVEKSLRGAAIWDELKDRLhtnaYSLSGGQQQRVCIARC 193
Cdd:TIGR03608 77 KLGYLFQN---FAlienETVEENLDLGLKYK-KLSKKEKREKKKEALEKVGLNLKLKQKI----YELSGGEQQRVALARA 148
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 580041203 194 LAIEPEVILMDEPTSALDPISTLRVEELVQELKEK-YTIIMVTHNM---QQAARV 244
Cdd:TIGR03608 149 ILKPPPLILADEPTGSLDPKNRDEVLDLLLELNDEgKTIIIVTHDPevaKQADRV 203
|
|
| cbiO |
PRK13646 |
energy-coupling factor transporter ATPase; |
48-277 |
1.90e-29 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 112.95 E-value: 1.90e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 48 ENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILYRDQDIFDQKYSKE--QLRTNVGMVFQQ 125
Cdd:PRK13646 19 EHQAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLK-----PTTGTVTVDDITITHKTKDKYirPVRKRIGMVFQF 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 126 PNP--FPKSIYDNITYGPKIHGIKnkkvLDEIVEKSLRGAAIWDELKDRLHTNAYSLSGGQQQRVCIARCLAIEPEVILM 203
Cdd:PRK13646 94 PESqlFEDTVEREIIFGPKNFKMN----LDEVKNYAHRLLMDLGFSRDVMSQSPFQMSGGQMRKIAIVSILAMNPDIIVL 169
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 580041203 204 DEPTSALDPISTLRVEELVQEL--KEKYTIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSnpSNKKTEDY 277
Cdd:PRK13646 170 DEPTAGLDPQSKRQVMRLLKSLqtDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKELFK--DKKKLADW 243
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
38-274 |
2.32e-29 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 111.10 E-value: 2.32e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 38 STQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTyikTLNRMVELVPSvkTAGKILYRDQDIFDQKYSKeqlRT 117
Cdd:cd03218 2 RAENLSKRYGKRKVVNGVSLSVKQGEIVGLLGPNGAGKTT---TFYMIVGLVKP--DSGKILLDGQDITKLPMHK---RA 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 118 NVGMVF--QQPNPFPK-SIYDNITYGPKIHGiKNKKVLDEIVEKSLrgaaiwDELK-DRL-HTNAYSLSGGQQQRVCIAR 192
Cdd:cd03218 74 RLGIGYlpQEASIFRKlTVEENILAVLEIRG-LSKKEREEKLEELL------EEFHiTHLrKSKASSLSGGERRRVEIAR 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 193 CLAIEPEVILMDEPTSALDPISTLRVEELVQELKEKYTIIMVT-HNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNPSN 271
Cdd:cd03218 147 ALATNPKFLLLDEPFAGVDPIAVQDIQKIIKILKDRGIGVLITdHNVRETLSITDRAYIIYEGKVLAEGTPEEIAANELV 226
|
...
gi 580041203 272 KKT 274
Cdd:cd03218 227 RKV 229
|
|
| ABC_BcrA_bacitracin_resist |
cd03268 |
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ... |
38-254 |
3.45e-29 |
|
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.
Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 110.00 E-value: 3.45e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 38 STQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTlnrMVELVPsvKTAGKILYRDQDIFDqkySKEQLRt 117
Cdd:cd03268 2 KTNDLTKTYGKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKI---ILGLIK--PDSGEITFDGKSYQK---NIEALR- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 118 NVGMVFQQPNPFPK-SIYDNITYGPKIHGIKNKKVlDEIVEKSlrgaaiwdELKDRLHTNAYSLSGGQQQRVCIARCLAI 196
Cdd:cd03268 73 RIGALIEAPGFYPNlTARENLRLLARLLGIRKKRI-DEVLDVV--------GLKDSAKKKVKGFSLGMKQRLGIALALLG 143
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 580041203 197 EPEVILMDEPTSALDPISTLRVEELVQELKEK-YTIIMVTHNMQQAARVSDKTAFFLNG 254
Cdd:cd03268 144 NPDLLILDEPTNGLDPDGIKELRELILSLRDQgITVLISSHLLSEIQKVADRIGIINKG 202
|
|
| ABCC_TAP |
cd03248 |
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ... |
52-243 |
4.64e-29 |
|
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.
Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 110.25 E-value: 4.64e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 52 LQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELvpsvkTAGKILYRDQDIfdQKYSKEQLRTNVGMVFQQPNPFPK 131
Cdd:cd03248 30 LQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQP-----QGGQVLLDGKPI--SQYEHKYLHSKVSLVGQEPVLFAR 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 132 SIYDNITYGpkihgiKNKKVLDEIVEKSLRGAA--IWDELKDRLHTNA----YSLSGGQQQRVCIARCLAIEPEVILMDE 205
Cdd:cd03248 103 SLQDNIAYG------LQSCSFECVKEAAQKAHAhsFISELASGYDTEVgekgSQLSGGQKQRVAIARALIRNPQVLILDE 176
|
170 180 190
....*....|....*....|....*....|....*...
gi 580041203 206 PTSALDPISTLRVEELVQELKEKYTIIMVTHNMQQAAR 243
Cdd:cd03248 177 ATSALDAESEQQVQQALYDWPERRTVLVIAHRLSTVER 214
|
|
| MsbA_lipidA |
TIGR02203 |
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ... |
51-236 |
5.13e-29 |
|
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]
Pssm-ID: 131258 [Multi-domain] Cd Length: 571 Bit Score: 115.58 E-value: 5.13e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 51 ALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILYRDQDIfdQKYSKEQLRTNVGMVFQQPNPFP 130
Cdd:TIGR02203 347 ALDSISLVIEPGETVALVGRSGSGKSTLVNLIPRFYE-----PDSGQILLDGHDL--ADYTLASLRRQVALVSQDVVLFN 419
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 131 KSIYDNITYGpkihgiKNKKVLDEIVEKSLRGA---AIWDELKDRLHT----NAYSLSGGQQQRVCIARCLAIEPEVILM 203
Cdd:TIGR02203 420 DTIANNIAYG------RTEQADRAEIERALAAAyaqDFVDKLPLGLDTpigeNGVLLSGGQRQRLAIARALLKDAPILIL 493
|
170 180 190
....*....|....*....|....*....|...
gi 580041203 204 DEPTSALDPISTLRVEELVQELKEKYTIIMVTH 236
Cdd:TIGR02203 494 DEATSALDNESERLVQAALERLMQGRTTLVIAH 526
|
|
| thiQ |
TIGR01277 |
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ... |
43-262 |
5.41e-29 |
|
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]
Pssm-ID: 130344 [Multi-domain] Cd Length: 213 Bit Score: 109.57 E-value: 5.41e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 43 DLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELVpsvktAGKILYRDQDIFDQKYSkeqlRTNVGMV 122
Cdd:TIGR01277 5 KVRYEYEHLPMEFDLNVADGEIVAIMGPSGAGKSTLLNLIAGFIEPA-----SGSIKVNDQSHTGLAPY----QRPVSML 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 123 FQQPNPFPK-SIYDNITYGPKiHGIKNKKVLDEIVEKSLRGAAIwDELKDRLHTnaySLSGGQQQRVCIARCLAIEPEVI 201
Cdd:TIGR01277 76 FQENNLFAHlTVRQNIGLGLH-PGLKLNAEQQEKVVDAAQQVGI-ADYLDRLPE---QLSGGQRQRVALARCLVRPNPIL 150
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 580041203 202 LMDEPTSALDPIstLRVE--ELVQEL--KEKYTIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDT 262
Cdd:TIGR01277 151 LLDEPFSALDPL--LREEmlALVKQLcsERQRTLLMVTHHLSDARAIASQIAVVSQGKIKVVSDC 213
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
41-254 |
1.33e-28 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 107.78 E-value: 1.33e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 41 NLDLWYGEN--HALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRmvELVPSvktAGKILYRDQDIfdQKYsKEQLRTN 118
Cdd:cd03247 5 NVSFSYPEQeqQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTG--DLKPQ---QGEITLDGVPV--SDL-EKALSSL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 119 VGMVFQQPNPFPKSIYDNItygpkihGIKnkkvldeivekslrgaaiwdelkdrlhtnaysLSGGQQQRVCIARCLAIEP 198
Cdd:cd03247 77 ISVLNQRPYLFDTTLRNNL-------GRR--------------------------------FSGGERQRLALARILLQDA 117
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 580041203 199 EVILMDEPTSALDPISTLRVEELV-QELKEKyTIIMVTHNMQQAARVsDKTAFFLNG 254
Cdd:cd03247 118 PIVLLDEPTVGLDPITERQLLSLIfEVLKDK-TLIWITHHLTGIEHM-DKILFLENG 172
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
37-244 |
1.34e-28 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 107.30 E-value: 1.34e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 37 YSTQNLDLWYGENHA--LQNINLDIYENQITAIIGPSGCGKSTYIKTlnrMVELVPSvkTAGKILYRDQDIfdQKYSKEQ 114
Cdd:cd03246 1 LEVENVSFRYPGAEPpvLRNVSFSIEPGESLAIIGPSGSGKSTLARL---ILGLLRP--TSGRVRLDGADI--SQWDPNE 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 115 LRTNVGMVFQQPNPFPKSIYDNItygpkihgiknkkvldeivekslrgaaiwdelkdrlhtnaysLSGGQQQRVCIARCL 194
Cdd:cd03246 74 LGDHVGYLPQDDELFSGSIAENI------------------------------------------LSGGQRQRLGLARAL 111
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 580041203 195 AIEPEVILMDEPTSALDPISTLRVEELVQELKEK-YTIIMVTHNM---QQAARV 244
Cdd:cd03246 112 YGNPRILVLDEPNSHLDVEGERALNQAIAALKAAgATRIVIAHRPetlASADRI 165
|
|
| urea_trans_UrtE |
TIGR03410 |
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ... |
40-246 |
1.62e-28 |
|
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 274567 [Multi-domain] Cd Length: 230 Bit Score: 108.77 E-value: 1.62e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLnrmVELVPSvkTAGKILYRDQDIFDQKySKEQLRTNV 119
Cdd:TIGR03410 4 SNLNVYYGQSHILRGVSLEVPKGEVTCVLGRNGVGKTTLLKTL---MGLLPV--KSGSIRLDGEDITKLP-PHERARAGI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 120 GMVFQQPNPFPK-SIYDNITYGPKIHGIKNKKVLDEIVEkslrgaaIWDELKDRLHTNAYSLSGGQQQRVCIARCLAIEP 198
Cdd:TIGR03410 78 AYVPQGREIFPRlTVEENLLTGLAALPRRSRKIPDEIYE-------LFPVLKEMLGRRGGDLSGGQQQQLAIARALVTRP 150
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 580041203 199 EVILMDEPTSALDPISTLRVEELVQELKEK--YTIIMVTHNMQQAARVSD 246
Cdd:TIGR03410 151 KLLLLDEPTEGIQPSIIKDIGRVIRRLRAEggMAILLVEQYLDFARELAD 200
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
40-247 |
1.77e-28 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 109.48 E-value: 1.77e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRmvELVPSvktAGKILYRDQDIFDqkYSKEQLRTNV 119
Cdd:PRK13548 6 RNLSVRLGGRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSG--ELSPD---SGEVRLNGRPLAD--WSPAELARRR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 120 GMVFQQPN-PFPKSIYDNITYGPKIHGIKNKKVlDEIVEKSLRGAAIWDeLKDRLHTnaySLSGGQQQRVCIARCLA--- 195
Cdd:PRK13548 79 AVLPQHSSlSFPFTVEEVVAMGRAPHGLSRAED-DALVAAALAQVDLAH-LAGRDYP---QLSGGEQQRVQLARVLAqlw 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 580041203 196 ---IEPEVILMDEPTSALDPISTLRVEELVQEL--KEKYTIIMVTHNMQQAARVSDK 247
Cdd:PRK13548 154 epdGPPRWLLLDEPTSALDLAHQHHVLRLARQLahERGLAVIVVLHDLNLAARYADR 210
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
38-246 |
2.52e-28 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 107.75 E-value: 2.52e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 38 STQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILYRDqdifdqkyskeqlrt 117
Cdd:cd03269 2 EVENVTKRFGRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIIL-----PDSGEVLFDG--------------- 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 118 nvgmvfqqpNPFPKSIYDNITYGPKIHGI-KNKKVLDEIVE-KSLRG-----AAIW-DELKDRLHTNAY------SLSGG 183
Cdd:cd03269 62 ---------KPLDIAARNRIGYLPEERGLyPKMKVIDQLVYlAQLKGlkkeeARRRiDEWLERLELSEYankrveELSKG 132
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 580041203 184 QQQRVCIARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEK-YTIIMVTHNMQQAARVSD 246
Cdd:cd03269 133 NQQKVQFIAAVIHDPELLILDEPFSGLDPVNVELLKDVIRELARAgKTVILSTHQMELVEELCD 196
|
|
| type_I_sec_LssB |
TIGR03375 |
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some ... |
48-239 |
2.54e-28 |
|
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. This model is related to models TIGR01842 and TIGR01846, and to bacteriocin ABC transporters that cleave their substrates during export. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]
Pssm-ID: 274550 [Multi-domain] Cd Length: 694 Bit Score: 113.81 E-value: 2.54e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 48 ENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELvpsvkTAGKILYRDQDIfdQKYSKEQLRTNVGMVFQQPN 127
Cdd:TIGR03375 477 ETPALDNVSLTIRPGEKVAIIGRIGSGKSTLLKLLLGLYQP-----TEGSVLLDGVDI--RQIDPADLRRNIGYVPQDPR 549
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 128 PFPKSIYDNITYGpkihgikNKKVLDEIVEKSLRGAAIwDELKdRLHTNAY---------SLSGGQQQRVCIARCLAIEP 198
Cdd:TIGR03375 550 LFYGTLRDNIALG-------APYADDEEILRAAELAGV-TEFV-RRHPDGLdmqigergrSLSGGQRQAVALARALLRDP 620
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 580041203 199 EVILMDEPTSALDPISTLRVEELVQELKEKYTIIMVTHNMQ 239
Cdd:TIGR03375 621 PILLLDEPTSAMDNRSEERFKDRLKRWLAGKTLVLVTHRTS 661
|
|
| cbiO |
PRK13643 |
energy-coupling factor transporter ATPase; |
49-256 |
3.36e-28 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 109.44 E-value: 3.36e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 49 NHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKIlyRDQDIFDQKYSKEQ----LRTNVGMVFQ 124
Cdd:PRK13643 19 SRALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQ-----PTEGKV--TVGDIVVSSTSKQKeikpVRKKVGVVFQ 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 125 QPNP--FPKSIYDNITYGPKIHGIkNKKVLDEIVEKSLRGAAIWDELKDRlhtNAYSLSGGQQQRVCIARCLAIEPEVIL 202
Cdd:PRK13643 92 FPESqlFEETVLKDVAFGPQNFGI-PKEKAEKIAAEKLEMVGLADEFWEK---SPFELSGGQMRRVAIAGILAMEPEVLV 167
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 580041203 203 MDEPTSALDPISTLRVEELVQELKEK-YTIIMVTHNMQQAARVSDKTAFFLNGYV 256
Cdd:PRK13643 168 LDEPTAGLDPKARIEMMQLFESIHQSgQTVVLVTHLMDDVADYADYVYLLEKGHI 222
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
46-246 |
4.81e-28 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 109.04 E-value: 4.81e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 46 YGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILYRDQdifdqkyskeqlrtnvgmvfqq 125
Cdd:COG4152 11 FGDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILA-----PDSGEVLWDGE---------------------- 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 126 pnPFPKSIYDNITYGPKIHGI-KNKKVLDEIV----------EKSLRGAAIWDE---LKDRLHTNAYSLSGGQQQRVCIA 191
Cdd:COG4152 64 --PLDPEDRRRIGYLPEERGLyPKMKVGEQLVylarlkglskAEAKRRADEWLErlgLGDRANKKVEELSKGNQQKVQLI 141
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 580041203 192 RCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEK-YTIIMVTHNMQQAARVSD 246
Cdd:COG4152 142 AALLHDPELLILDEPFSGLDPVNVELLKDVIRELAAKgTTVIFSSHQMELVEELCD 197
|
|
| 3a01208 |
TIGR00958 |
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other] |
52-269 |
7.28e-28 |
|
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 112.51 E-value: 7.28e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 52 LQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILYRDQDI--FDQKYskeqLRTNVGMVFQQPNPF 129
Cdd:TIGR00958 497 LKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQ-----PTGGQVLLDGVPLvqYDHHY----LHRQVALVGQEPVLF 567
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 130 PKSIYDNITYGPKihgiknkKVLDEIVEKSLRGAAIWD---ELKDRLHTN----AYSLSGGQQQRVCIARCLAIEPEVIL 202
Cdd:TIGR00958 568 SGSVRENIAYGLT-------DTPDEEIMAAAKAANAHDfimEFPNGYDTEvgekGSQLSGGQKQRIAIARALVRKPRVLI 640
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 580041203 203 MDEPTSALDpistLRVEELVQELKEKY--TIIMVTHNMQQAARvSDKTAFFLNGYVNEYDDTDKIFSNP 269
Cdd:TIGR00958 641 LDEATSALD----AECEQLLQESRSRAsrTVLLIAHRLSTVER-ADQILVLKKGSVVEMGTHKQLMEDQ 704
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
40-236 |
8.13e-28 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 107.48 E-value: 8.13e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRmvELVPsvkTAGKILYrdqdIFDQKYSKE---QLR 116
Cdd:COG1119 7 RNVTVRRGGKTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITG--DLPP---TYGNDVR----LFGERRGGEdvwELR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 117 TNVGMV---FQQPnpFPKSI----------YDNItygpkihGIkNKKVLDEIVEKSLRGAAIW--DELKDR-LHTnaysL 180
Cdd:COG1119 78 KRIGLVspaLQLR--FPRDEtvldvvlsgfFDSI-------GL-YREPTDEQRERARELLELLglAHLADRpFGT----L 143
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 580041203 181 SGGQQQRVCIARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEKY--TIIMVTH 236
Cdd:COG1119 144 SQGEQRRVLIARALVKDPELLILDEPTAGLDLGARELLLALLDKLAAEGapTLVLVTH 201
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
40-236 |
1.16e-27 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 106.02 E-value: 1.16e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLnrmVELVPSvkTAGKILYRDQDIFDQKyskEQLRTNV 119
Cdd:COG4133 6 ENLSCRRGERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRIL---AGLLPP--SAGEVLWNGEPIRDAR---EDYRRRL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 120 GMVFQQPNPFPK-SIYDNITYGPKIHGIknkkvldeivekSLRGAAIWD-----ELKDRLHTNAYSLSGGQQQRVCIARC 193
Cdd:COG4133 78 AYLGHADGLKPElTVRENLRFWAALYGL------------RADREAIDEaleavGLAGLADLPVRQLSAGQKRRVALARL 145
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 580041203 194 LAIEPEVILMDEPTSALDPISTLRVEELVQE-LKEKYTIIMVTH 236
Cdd:COG4133 146 LLSPAPLWLLDEPFTALDAAGVALLAELIAAhLARGGAVLLTTH 189
|
|
| potG |
PRK11607 |
putrescine ABC transporter ATP-binding subunit PotG; |
40-278 |
1.32e-27 |
|
putrescine ABC transporter ATP-binding subunit PotG;
Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 109.54 E-value: 1.32e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMvelvpSVKTAGKILYRDQDIFD-QKYSKEqlrtn 118
Cdd:PRK11607 23 RNLTKSFDGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGF-----EQPTAGQIMLDGVDLSHvPPYQRP----- 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 119 VGMVFQQPNPFPK-SIYDNITYGPKihgiKNKKVLDEI---VEKSLRGAAIWDELKDRLHtnaySLSGGQQQRVCIARCL 194
Cdd:PRK11607 93 INMMFQSYALFPHmTVEQNIAFGLK----QDKLPKAEIasrVNEMLGLVHMQEFAKRKPH----QLSGGQRQRVALARSL 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 195 AIEPEVILMDEPTSALDPISTLRVEELVQELKEKY--TIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNPSNK 272
Cdd:PRK11607 165 AKRPKLLLLDEPMGALDKKLRDRMQLEVVDILERVgvTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEPEEIYEHPTTR 244
|
....*.
gi 580041203 273 KTEDYI 278
Cdd:PRK11607 245 YSAEFI 250
|
|
| PhnK |
COG1101 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
48-248 |
2.05e-27 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 106.71 E-value: 2.05e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 48 ENHALQNINLDIYENQITAIIGPSGCGKSTyikTLNrMV--ELVPsvkTAGKILYRDQDIfdqKYSKEQLRTN-VGMVFQ 124
Cdd:COG1101 18 EKRALDGLNLTIEEGDFVTVIGSNGAGKST---LLN-AIagSLPP---DSGSILIDGKDV---TKLPEYKRAKyIGRVFQ 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 125 qpNPF----PK-SIYDNI--------TYGPKIhGIkNKKVLDEIVE--KSLR-GaaiwdeLKDRLHTNAYSLSGGQQQRV 188
Cdd:COG1101 88 --DPMmgtaPSmTIEENLalayrrgkRRGLRR-GL-TKKRRELFREllATLGlG------LENRLDTKVGLLSGGQRQAL 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 580041203 189 CIARCLAIEPEVILMDEPTSALDPISTLRVEELVQEL--KEKYTIIMVTHNMQQAARVSDKT 248
Cdd:COG1101 158 SLLMATLTKPKLLLLDEHTAALDPKTAALVLELTEKIveENNLTTLMVTHNMEQALDYGNRL 219
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
40-260 |
5.79e-27 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 104.50 E-value: 5.79e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGENH--ALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELvpsvkTAGKILYRDQDIfdQKYSKEQLRT 117
Cdd:cd03244 6 KNVSLRYRPNLppVLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVEL-----SSGSILIDGVDI--SKIGLHDLRS 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 118 NVGMVFQQPNPFPKSIYDNItyGP-------KIHGIKNKKVLDEIVEKSLRGaaiwdeLKDRLHTNAYSLSGGQQQRVCI 190
Cdd:cd03244 79 RISIIPQDPVLFSGTIRSNL--DPfgeysdeELWQALERVGLKEFVESLPGG------LDTVVEEGGENLSVGQRQLLCL 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 580041203 191 ARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEKYTIIMVTHnmqqaaRV-----SDKTAFFLNGYVNEYD 260
Cdd:cd03244 151 ARALLRKSKILVLDEATASVDPETDALIQKTIREAFKDCTVLTIAH------RLdtiidSDRILVLDKGRVVEFD 219
|
|
| cbiO |
PRK13644 |
energy-coupling factor transporter ATPase; |
51-270 |
9.42e-27 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 105.45 E-value: 9.42e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 51 ALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMveLVPSvktAGKILYRDQDIFDqkYSKEQ-LRTNVGMVFQQPNP- 128
Cdd:PRK13644 17 ALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGL--LRPQ---KGKVLVSGIDTGD--FSKLQgIRKLVGIVFQNPETq 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 129 -FPKSIYDNITYGPK---IHGIKNKKVLDEIVEKSlrgaaiwdELKDRLHTNAYSLSGGQQQRVCIARCLAIEPEVILMD 204
Cdd:PRK13644 90 fVGRTVEEDLAFGPEnlcLPPIEIRKRVDRALAEI--------GLEKYRHRSPKTLSGGQGQCVALAGILTMEPECLIFD 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 580041203 205 EPTSALDPISTLRVEELVQELKEK-YTIIMVTHNMQQaARVSDKTAFFLNGYVNEYDDTDKIFSNPS 270
Cdd:PRK13644 162 EVTSMLDPDSGIAVLERIKKLHEKgKTIVYITHNLEE-LHDADRIIVMDRGKIVLEGEPENVLSDVS 227
|
|
| PRK10253 |
PRK10253 |
iron-enterobactin ABC transporter ATP-binding protein; |
40-243 |
1.10e-26 |
|
iron-enterobactin ABC transporter ATP-binding protein;
Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 105.07 E-value: 1.10e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMveLVPSvktAGKILYRDQDIfdQKYSKEQLRTNV 119
Cdd:PRK10253 11 EQLTLGYGKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRL--MTPA---HGHVWLDGEHI--QHYASKEVARRI 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 120 GMVFQQP-NPFPKSIYDNITYGPKIHG---IKNKKVLDEIVEKSLRGAAIWDELKDRLHTnaysLSGGQQQRVCIARCLA 195
Cdd:PRK10253 84 GLLAQNAtTPGDITVQELVARGRYPHQplfTRWRKEDEEAVTKAMQATGITHLADQSVDT----LSGGQRQRAWIAMVLA 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 580041203 196 IEPEVILMDEPTSALDPISTLRVEELVQEL-KEK-YTIIMVTHNMQQAAR 243
Cdd:PRK10253 160 QETAIMLLDEPTTWLDISHQIDLLELLSELnREKgYTLAAVLHDLNQACR 209
|
|
| COG4559 |
COG4559 |
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism]; |
40-247 |
1.15e-26 |
|
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443620 [Multi-domain] Cd Length: 258 Bit Score: 104.43 E-value: 1.15e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRmvELVPsvkTAGKILYRDQDIfdQKYSKEQLRTNV 119
Cdd:COG4559 5 ENLSVRLGGRTLLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTG--ELTP---SSGEVRLNGRPL--AAWSPWELARRR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 120 GMVFQQPN-PFPKSIYDNITYGpKIHGIKNKKVLDEIVEKSLRGAAIWDeLKDRLHTnaySLSGGQQQRVCIARCLA--- 195
Cdd:COG4559 78 AVLPQHSSlAFPFTVEEVVALG-RAPHGSSAAQDRQIVREALALVGLAH-LAGRSYQ---TLSGGEQQRVQLARVLAqlw 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 580041203 196 ----IEPEVILMDEPTSALDPISTLRVEELVQEL-KEKYTIIMVTHNMQQAARVSDK 247
Cdd:COG4559 153 epvdGGPRWLFLDEPTSALDLAHQHAVLRLARQLaRRGGGVVAVLHDLNLAAQYADR 209
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
50-256 |
1.21e-26 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 103.60 E-value: 1.21e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 50 HALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvPSvktAGKILYrdqDIFDQKYSKEQLRTNVGMVFQQPNPF 129
Cdd:cd03266 19 QAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLE--PD---AGFATV---DGFDVVKEPAEARRRLGFVSDSTGLY 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 130 PK-SIYDNITYGPKIHGIKNKKVLDEIvekslrgaaiwDELKDRLHTNAY------SLSGGQQQRVCIARCLAIEPEVIL 202
Cdd:cd03266 91 DRlTARENLEYFAGLYGLKGDELTARL-----------EELADRLGMEELldrrvgGFSTGMRQKVAIARALVHDPPVLL 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 580041203 203 MDEPTSALDPISTLRVEELVQELKEK-YTIIMVTHNMQQAARVSDKTAFFLNGYV 256
Cdd:cd03266 160 LDEPTTGLDVMATRALREFIRQLRALgKCILFSTHIMQEVERLCDRVVVLHRGRV 214
|
|
| thiQ |
PRK10771 |
thiamine ABC transporter ATP-binding protein ThiQ; |
43-267 |
1.24e-26 |
|
thiamine ABC transporter ATP-binding protein ThiQ;
Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 103.89 E-value: 1.24e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 43 DLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYiktLNRMVELVPSvkTAGKILYRDQDIFDQKYSKEQlrtnVGMV 122
Cdd:PRK10771 6 DITWLYHHLPMRFDLTVERGERVAILGPSGAGKSTL---LNLIAGFLTP--ASGSLTLNGQDHTTTPPSRRP----VSML 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 123 FQQPNPFPK-SIYDNITYGpkIH-GIK----NKKVLDEIVEK-SLrgaaiwDELKDRLHTnaySLSGGQQQRVCIARCLA 195
Cdd:PRK10771 77 FQENNLFSHlTVAQNIGLG--LNpGLKlnaaQREKLHAIARQmGI------EDLLARLPG---QLSGGQRQRVALARCLV 145
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 580041203 196 IEPEVILMDEPTSALDPisTLRVE--ELVQEL--KEKYTIIMVTHNMQQAARVSDKTAFFLNGYVnEYD-DTDKIFS 267
Cdd:PRK10771 146 REQPILLLDEPFSALDP--ALRQEmlTLVSQVcqERQLTLLMVSHSLEDAARIAPRSLVVADGRI-AWDgPTDELLS 219
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
45-237 |
3.05e-26 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 107.45 E-value: 3.05e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 45 WYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMveLVPSvktAGKILYRDQDIfdQKYSKEQLRTNVGMVFQ 124
Cdd:TIGR02868 344 YPGAPPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGL--LDPL---QGEVTLDGVPV--SSLDQDEVRRRVSVCAQ 416
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 125 QPNPFPKSIYDNITYGpkihgikNKKVLDEIVEKSLRGA--AIW-DELKDRLHT----NAYSLSGGQQQRVCIARCLAIE 197
Cdd:TIGR02868 417 DAHLFDTTVRENLRLA-------RPDATDEELWAALERVglADWlRALPDGLDTvlgeGGARLSGGERQRLALARALLAD 489
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 580041203 198 PEVILMDEPTSALDPISTLRVEELVQELKEKYTIIMVTHN 237
Cdd:TIGR02868 490 APILLLDEPTEHLDAETADELLEDLLAALSGRTVVLITHH 529
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
48-274 |
3.83e-26 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 107.63 E-value: 3.83e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 48 ENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILYRDQDIFDQKYSKEQ-LRTNVGMVFQQP 126
Cdd:PRK10261 336 EVHAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVE-----SQGGEIIFNGQRIDTLSPGKLQaLRRDIQFIFQDP 410
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 127 ----NPfPKSIYDNITYGPKIHGIKNKKVLDEIVEKSLRGAAIWDELKDRLhtnAYSLSGGQQQRVCIARCLAIEPEVIL 202
Cdd:PRK10261 411 yaslDP-RQTVGDSIMEPLRVHGLLPGKAAAARVAWLLERVGLLPEHAWRY---PHEFSGGQRQRICIARALALNPKVII 486
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 580041203 203 MDEPTSALDPISTLRVEELVQELKEKYTI--IMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNPSNKKT 274
Cdd:PRK10261 487 ADEAVSALDVSIRGQIINLLLDLQRDFGIayLFISHDMAVVERISHRVAVMYLGQIVEIGPRRAVFENPQHPYT 560
|
|
| PRK11176 |
PRK11176 |
lipid A ABC transporter ATP-binding protein/permease MsbA; |
48-236 |
4.40e-26 |
|
lipid A ABC transporter ATP-binding protein/permease MsbA;
Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 107.03 E-value: 4.40e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 48 ENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELvpsvkTAGKILYRDQDIfdQKYSKEQLRTNVGMVFQQPN 127
Cdd:PRK11176 355 EVPALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDI-----DEGEILLDGHDL--RDYTLASLRNQVALVSQNVH 427
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 128 PFPKSIYDNITYGpkihgiKNKKVLDEIVEKSLRGAAIWD---ELKDRLHT----NAYSLSGGQQQRVCIARCLAIEPEV 200
Cdd:PRK11176 428 LFNDTIANNIAYA------RTEQYSREQIEEAARMAYAMDfinKMDNGLDTvigeNGVLLSGGQRQRIAIARALLRDSPI 501
|
170 180 190
....*....|....*....|....*....|....*.
gi 580041203 201 ILMDEPTSALDPISTLRVEELVQELKEKYTIIMVTH 236
Cdd:PRK11176 502 LILDEATSALDTESERAIQAALDELQKNRTSLVIAH 537
|
|
| ModC |
COG4148 |
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ... |
54-269 |
1.13e-25 |
|
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis
Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 104.03 E-value: 1.13e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 54 NINLDIYENQITAIIGPSGCGKSTYIktlnRMVE-LVPSvkTAGKILYRDQDIFDqkyskEQLRTNV-------GMVFQQ 125
Cdd:COG4148 17 DVDFTLPGRGVTALFGPSGSGKTTLL----RAIAgLERP--DSGRIRLGGEVLQD-----SARGIFLpphrrriGYVFQE 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 126 PNPFP-KSIYDNITYGPKIHGIKNKKV-LDEIVEkslrgaaiWDELKDRLHTNAYSLSGGQQQRVCIARCLAIEPEVILM 203
Cdd:COG4148 86 ARLFPhLSVRGNLLYGRKRAPRAERRIsFDEVVE--------LLGIGHLLDRRPATLSGGERQRVAIGRALLSSPRLLLM 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 204 DEPTSALDPISTLRV----EELVQELkeKYTIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNP 269
Cdd:COG4148 158 DEPLAALDLARKAEIlpylERLRDEL--DIPILYVSHSLDEVARLADHVVLLEQGRVVASGPLAEVLSRP 225
|
|
| livF |
PRK11614 |
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF; |
35-268 |
1.76e-25 |
|
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 101.11 E-value: 1.76e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 35 VIYSTQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLnrmveLVPSVKTAGKILYRDQDIFDQKYSKeQ 114
Cdd:PRK11614 4 VMLSFDKVSAHYGKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTL-----CGDPRATSGRIVFDGKDITDWQTAK-I 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 115 LRTNVGMVFQQPNPFPK-SIYDNITYGpkihGIKNKKvlDEIVEKSLRGAAIWDELKDRLHTNAYSLSGGQQQRVCIARC 193
Cdd:PRK11614 78 MREAVAIVPEGRRVFSRmTVEENLAMG----GFFAER--DQFQERIKWVYELFPRLHERRIQRAGTMSGGEQQMLAIGRA 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 580041203 194 LAIEPEVILMDEPTSALDPISTLRVEELVQELKEK-YTIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSN 268
Cdd:PRK11614 152 LMSQPRLLLLDEPSLGLAPIIIQQIFDTIEQLREQgMTIFLVEQNANQALKLADRGYVLENGHVVLEDTGDALLAN 227
|
|
| YnjD |
COG4136 |
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ... |
40-242 |
1.90e-25 |
|
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];
Pssm-ID: 443311 [Multi-domain] Cd Length: 211 Bit Score: 100.25 E-value: 1.90e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTyikTLNRMV-ELVPSVKTAGKILYRDQDIfdqkYSKEQLRTN 118
Cdd:COG4136 5 ENLTITLGGRPLLAPLSLTVAPGEILTLMGPSGSGKST---LLAAIAgTLSPAFSASGEVLLNGRRL----TALPAEQRR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 119 VGMVFQQPNPFPK-SIYDNITYG--PKIHGiKNKKvldEIVEKSLRGAaiwdELKDRLHTNAYSLSGGQQQRVCIARCLA 195
Cdd:COG4136 78 IGILFQDDLLFPHlSVGENLAFAlpPTIGR-AQRR---ARVEQALEEA----GLAGFADRDPATLSGGQRARVALLRALL 149
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 580041203 196 IEPEVILMDEPTSALDPISTLRVEELV-QELKEKYTI-IMVTHNMQQAA 242
Cdd:COG4136 150 AEPRALLLDEPFSKLDAALRAQFREFVfEQIRQRGIPaLLVTHDEEDAP 198
|
|
| PRK15079 |
PRK15079 |
oligopeptide ABC transporter ATP-binding protein OppF; Provisional |
51-279 |
2.23e-25 |
|
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 102.86 E-value: 2.23e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 51 ALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILYRDQDIFDQkySKEQL---RTNVGMVFQQP- 126
Cdd:PRK15079 36 AVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVK-----ATDGEVAWLGKDLLGM--KDDEWravRSDIQMIFQDPl 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 127 ---NPfPKSIYDNI-----TYGPKIHGIKNKKVLDEIVEK-SLRGAAIwdelkdrlhtNAY--SLSGGQQQRVCIARCLA 195
Cdd:PRK15079 109 aslNP-RMTIGEIIaeplrTYHPKLSRQEVKDRVKAMMLKvGLLPNLI----------NRYphEFSGGQCQRIGIARALI 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 196 IEPEVILMDEPTSALDPISTLRVEELVQELKEKY--TIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNPSNKK 273
Cdd:PRK15079 178 LEPKLIICDEPVSALDVSIQAQVVNLLQQLQREMglSLIFIAHDLAVVKHISDRVLVMYLGHAVELGTYDEVYHNPLHPY 257
|
....*.
gi 580041203 274 TEDYIS 279
Cdd:PRK15079 258 TKALMS 263
|
|
| ugpC |
PRK11650 |
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC; |
45-244 |
4.42e-25 |
|
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
Pssm-ID: 236947 [Multi-domain] Cd Length: 356 Bit Score: 102.23 E-value: 4.42e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 45 WYGENHALQNINLDIYENQITAIIGPSGCGKSTyiktLNRMVELVPSVkTAGKILYRDQDIfDQKYSKEQlrtNVGMVFQ 124
Cdd:PRK11650 13 YDGKTQVIKGIDLDVADGEFIVLVGPSGCGKST----LLRMVAGLERI-TSGEIWIGGRVV-NELEPADR---DIAMVFQ 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 125 QPNPFPK-SIYDNITYGPKIHGIKNkkvlDEIVEKSLRGAAIWdELKDRLHTNAYSLSGGQQQRVCIARCLAIEPEVILM 203
Cdd:PRK11650 84 NYALYPHmSVRENMAYGLKIRGMPK----AEIEERVAEAARIL-ELEPLLDRKPRELSGGQRQRVAMGRAIVREPAVFLF 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 580041203 204 DEPTSALDpiSTLRVEELVqELKE-----KYTIIMVTHN----MQQAARV 244
Cdd:PRK11650 159 DEPLSNLD--AKLRVQMRL-EIQRlhrrlKTTSLYVTHDqveaMTLADRV 205
|
|
| ntrCD |
TIGR01184 |
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ... |
52-254 |
7.26e-25 |
|
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]
Pssm-ID: 130252 [Multi-domain] Cd Length: 230 Bit Score: 99.08 E-value: 7.26e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 52 LQNINLDIYENQITAIIGPSGCGKSTYiktLNRMVELvpSVKTAGKILYRDQDIfdQKYSKEQLrtnvgMVFQQPNPFP- 130
Cdd:TIGR01184 1 LKGVNLTIQQGEFISLIGHSGCGKSTL---LNLISGL--AQPTSGGVILEGKQI--TEPGPDRM-----VVFQNYSLLPw 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 131 KSIYDNITYG-----PKIHGIKNKKVLDEIVEK-SLRGAAiwdelkdrlHTNAYSLSGGQQQRVCIARCLAIEPEVILMD 204
Cdd:TIGR01184 69 LTVRENIALAvdrvlPDLSKSERRAIVEEHIALvGLTEAA---------DKRPGQLSGGMKQRVAIARALSIRPKVLLLD 139
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 580041203 205 EPTSALDPISTLRVEELVQELKEKY--TIIMVTHNMQQAARVSDKTAFFLNG 254
Cdd:TIGR01184 140 EPFGALDALTRGNLQEELMQIWEEHrvTVLMVTHDVDEALLLSDRVVMLTNG 191
|
|
| ABC_ATP_DarD |
NF038007 |
darobactin export ABC transporter ATP-binding protein; |
51-247 |
7.90e-25 |
|
darobactin export ABC transporter ATP-binding protein;
Pssm-ID: 411600 [Multi-domain] Cd Length: 218 Bit Score: 98.64 E-value: 7.90e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 51 ALQNINLDIYENQITAIIGPSGCGKSTYIKTLNrMVELVPSvktaGKILYRDQDIFDQKYS-KEQLRTN-VGMVFQQPNP 128
Cdd:NF038007 20 VLNHLNFSVEKGDFVSIMGPSGSGKSTLLNIIG-MFDSLDS----GSLTLAGKEVTNLSYSqKIILRRElIGYIFQSFNL 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 129 FPK-SIYDNITYGPKIHGIKNKkvldEIVEKSLRGAAIWDeLKDRLHTNAYSLSGGQQQRVCIARCLAIEPEVILMDEPT 207
Cdd:NF038007 95 IPHlSIFDNVALPLKYRGVAKK----ERIERVNQVLNLFG-IDNRRNHKPMQLSGGQQQRVAIARAMVSNPALLLADEPT 169
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 580041203 208 SALDPISTLRVEELVQELKEK-YTIIMVTHNmQQAARVSDK 247
Cdd:NF038007 170 GNLDSKNARAVLQQLKYINQKgTTIIMVTHS-DEASTYGNR 209
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
40-273 |
1.66e-24 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 98.43 E-value: 1.66e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTyikTLNRMVELVPsvKTAGKILYRDQDIFDQKYsKEQLRTNV 119
Cdd:PRK10895 7 KNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTT---TFYMVVGIVP--RDAGNIIIDDEDISLLPL-HARARRGI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 120 GMVFQQPNPFPK-SIYDNITYGPKIHGIKNKKVLDEIVEKSLRGAAIwDELKDRLhtnAYSLSGGQQQRVCIARCLAIEP 198
Cdd:PRK10895 81 GYLPQEASIFRRlSVYDNLMAVLQIRDDLSAEQREDRANELMEEFHI-EHLRDSM---GQSLSGGERRRVEIARALAANP 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 580041203 199 EVILMDEPTSALDPISTLRVEELVQELKEKYTIIMVT-HNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNPSNKK 273
Cdd:PRK10895 157 KFILLDEPFAGVDPISVIDIKRIIEHLRDSGLGVLITdHNVRETLAVCERAYIVSQGHLIAHGTPTEILQDEHVKR 232
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
47-237 |
1.86e-24 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 97.86 E-value: 1.86e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 47 GENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILYRDQDIfdQKYSKEQLRTNVGMVFQQP 126
Cdd:PRK10247 18 GDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLIS-----PTSGTLLFEGEDI--STLKPEIYRQQVSYCAQTP 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 127 NPFPKSIYDNITYgPkiHGIKNKKVLDEIVEKSLRGAAIWDELkdrLHTNAYSLSGGQQQRVCIARCLAIEPEVILMDEP 206
Cdd:PRK10247 91 TLFGDTVYDNLIF-P--WQIRNQQPDPAIFLDDLERFALPDTI---LTKNIAELSGGEKQRISLIRNLQFMPKVLLLDEI 164
|
170 180 190
....*....|....*....|....*....|...
gi 580041203 207 TSALDPISTLRVEELVQEL--KEKYTIIMVTHN 237
Cdd:PRK10247 165 TSALDESNKHNVNEIIHRYvrEQNIAVLWVTHD 197
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
51-258 |
2.21e-24 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 97.94 E-value: 2.21e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 51 ALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVelvpsVKTAGKILYRDQDIfdQKYSKEQLRTNVGMVFQQPNPFP 130
Cdd:cd03252 17 ILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFY-----VPENGRVLVDGHDL--ALADPAWLRRQVGVVLQENVLFN 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 131 KSIYDNITY---GPKIHGIknkkvldeIVEKSLRGA-AIWDELKDRLHT----NAYSLSGGQQQRVCIARCLAIEPEVIL 202
Cdd:cd03252 90 RSIRDNIALadpGMSMERV--------IEAAKLAGAhDFISELPEGYDTivgeQGAGLSGGQRQRIAIARALIHNPRILI 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 580041203 203 MDEPTSALDPISTLRVEELVQELKEKYTIIMVTHNMqQAARVSDKTAFFLNGYVNE 258
Cdd:cd03252 162 FDEATSALDYESEHAIMRNMHDICAGRTVIIIAHRL-STVKNADRIIVMEKGRIVE 216
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
52-236 |
2.24e-24 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 96.85 E-value: 2.24e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 52 LQNINLDIYENQITAIIGPSGCGKSTYIKTL-NRmvelVPSVKTAGKILYRDQDIFDQKYSKEqlrtnVGMVFQqpnpfp 130
Cdd:cd03213 25 LKNVSGKAKPGELTAIMGPSGAGKSTLLNALaGR----RTGLGVSGEVLINGRPLDKRSFRKI-----IGYVPQ------ 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 131 ksiyDNITYGpkihgiknkkvlDEIVEKSLRGAAiwdELKdrlhtnaySLSGGQQQRVCIARCLAIEPEVILMDEPTSAL 210
Cdd:cd03213 90 ----DDILHP------------TLTVRETLMFAA---KLR--------GLSGGERKRVSIALELVSNPSLLFLDEPTSGL 142
|
170 180
....*....|....*....|....*..
gi 580041203 211 DPISTLRVEELVQEL-KEKYTIIMVTH 236
Cdd:cd03213 143 DSSSALQVMSLLRRLaDTGRTIICSIH 169
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
52-235 |
2.79e-24 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 97.34 E-value: 2.79e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 52 LQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELVPSvkTAGKILYRDQDIfdqkySKEQLRTNVGMVFQQPNPFPK 131
Cdd:cd03234 23 LNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEGGGT--TSGQILFNGQPR-----KPDQFQKCVAYVRQDDILLPG 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 132 -SIYDNITYGPKI--HGIKNKKVLDEIVE-KSLRGAAIwdelKDRLHTNAYSLSGGQQQRVCIARCLAIEPEVILMDEPT 207
Cdd:cd03234 96 lTVRETLTYTAILrlPRKSSDAIRKKRVEdVLLRDLAL----TRIGGNLVKGISGGERRRVSIAVQLLWDPKVLILDEPT 171
|
170 180
....*....|....*....|....*...
gi 580041203 208 SALDPISTLRVEELVQELKEKYTIIMVT 235
Cdd:cd03234 172 SGLDSFTALNLVSTLSQLARRNRIVILT 199
|
|
| nickel_nikE |
TIGR02769 |
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ... |
36-267 |
2.82e-24 |
|
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 131816 [Multi-domain] Cd Length: 265 Bit Score: 98.34 E-value: 2.82e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 36 IYSTQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLnrmveLVPSVKTAGKILYRDQDIFDQK-YSKEQ 114
Cdd:TIGR02769 11 TYRTGGLFGAKQRAPVLTNVSLSIEEGETVGLLGRSGCGKSTLARLL-----LGLEKPAQGTVSFRGQDLYQLDrKQRRA 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 115 LRTNVGMVFQQ-PNPF-PKSIYDNITYGPkihgIKNKKVLDEIVEKS-----LRGAAIWDELKDRLhtnAYSLSGGQQQR 187
Cdd:TIGR02769 86 FRRDVQLVFQDsPSAVnPRMTVRQIIGEP----LRHLTSLDESEQKAriaelLDMVGLRSEDADKL---PRQLSGGQLQR 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 188 VCIARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEKYTI--IMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKI 265
Cdd:TIGR02769 159 INIARALAVKPKLIVLDEAVSNLDMVLQAVILELLRKLQQAFGTayLFITHDLRLVQSFCQRVAVMDKGQIVEECDVAQL 238
|
..
gi 580041203 266 FS 267
Cdd:TIGR02769 239 LS 240
|
|
| cbiO |
PRK13640 |
energy-coupling factor transporter ATPase; |
51-270 |
3.67e-24 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 98.33 E-value: 3.67e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 51 ALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMveLVP-----SVKTAGKILYRDQDIFDqkyskeqLRTNVGMVFQQ 125
Cdd:PRK13640 22 ALNDISFSIPRGSWTALIGHNGSGKSTISKLINGL--LLPddnpnSKITVDGITLTAKTVWD-------IREKVGIVFQN 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 126 P-NPF-PKSIYDNITYGPKIHGIKNKKVLdEIVEKSLRGAAIWDELKdrlhTNAYSLSGGQQQRVCIARCLAIEPEVILM 203
Cdd:PRK13640 93 PdNQFvGATVGDDVAFGLENRAVPRPEMI-KIVRDVLADVGMLDYID----SEPANLSGGQKQRVAIAGILAVEPKIIIL 167
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 580041203 204 DEPTSALDPISTLRVEELVQELKEK--YTIIMVTHNMQQAArVSDKTAFFLNGYVNEYDDTDKIFSNPS 270
Cdd:PRK13640 168 DESTSMLDPAGKEQILKLIRKLKKKnnLTVISITHDIDEAN-MADQVLVLDDGKLLAQGSPVEIFSKVE 235
|
|
| PRK13657 |
PRK13657 |
glucan ABC transporter ATP-binding protein/ permease; |
47-258 |
4.93e-24 |
|
glucan ABC transporter ATP-binding protein/ permease;
Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 101.19 E-value: 4.93e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 47 GENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvPsvkTAGKILYRDQDIfdQKYSKEQLRTNVGMVFQQP 126
Cdd:PRK13657 346 NSRQGVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFD--P---QSGRILIDGTDI--RTVTRASLRRNIAVVFQDA 418
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 127 NPFPKSIYDNITYGpkihgikNKKVLDEIVEKSLRGAAIWDELK---DRLHTNA----YSLSGGQQQRVCIARCLAIEPE 199
Cdd:PRK13657 419 GLFNRSIEDNIRVG-------RPDATDEEMRAAAERAQAHDFIErkpDGYDTVVgergRQLSGGERQRLAIARALLKDPP 491
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 580041203 200 VILMDEPTSALDPISTLRVEELVQELKEKYTIIMVTHNMqQAARVSDKTAFFLNGYVNE 258
Cdd:PRK13657 492 ILILDEATSALDVETEAKVKAALDELMKGRTTFIIAHRL-STVRNADRILVFDNGRVVE 549
|
|
| LptB |
COG1137 |
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ... |
38-237 |
4.95e-24 |
|
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 97.02 E-value: 4.95e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 38 STQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTyikTLNRMVELVPSvkTAGKILYRDQDIFDQKYSKeqlRT 117
Cdd:COG1137 5 EAENLVKSYGKRTVVKDVSLEVNQGEIVGLLGPNGAGKTT---TFYMIVGLVKP--DSGRIFLDGEDITHLPMHK---RA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 118 NVGMVF--QQPNPFPK-SIYDNItygpkihgiknKKVLdEIVEKSLRG-AAIWDELKDRLH------TNAYSLSGGQQQR 187
Cdd:COG1137 77 RLGIGYlpQEASIFRKlTVEDNI-----------LAVL-ELRKLSKKErEERLEELLEEFGithlrkSKAYSLSGGERRR 144
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 580041203 188 VCIARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEKYTIIMVT-HN 237
Cdd:COG1137 145 VEIARALATNPKFILLDEPFAGVDPIAVADIQKIIRHLKERGIGVLITdHN 195
|
|
| ArpD |
COG4618 |
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ... |
47-267 |
2.08e-23 |
|
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 443660 [Multi-domain] Cd Length: 563 Bit Score: 99.44 E-value: 2.08e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 47 GENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLnrmVELVPSvkTAGKILYRDQDIFDqkYSKEQLRTNVGMVFQQP 126
Cdd:COG4618 343 SKRPILRGVSFSLEPGEVLGVIGPSGSGKSTLARLL---VGVWPP--TAGSVRLDGADLSQ--WDREELGRHIGYLPQDV 415
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 127 NPFPKSIYDNITYGPKIHgiknkkvlDEIVEKSLRGAAIwDELKDRL----HT----NAYSLSGGQQQRVCIARCLAIEP 198
Cdd:COG4618 416 ELFDGTIAENIARFGDAD--------PEKVVAAAKLAGV-HEMILRLpdgyDTrigeGGARLSGGQRQRIGLARALYGDP 486
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 199 EVILMDEPTSALDPISTLRVEELVQELKE-KYTIIMVTHNMqQAARVSDKTAFFLNGYVNEYDDTDKIFS 267
Cdd:COG4618 487 RLVVLDEPNSNLDDEGEAALAAAIRALKArGATVVVITHRP-SLLAAVDKLLVLRDGRVQAFGPRDEVLA 555
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
46-247 |
2.23e-23 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 98.95 E-value: 2.23e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 46 YGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILYRDQDIfDQKYSKEQLRTNVGMVFQQ 125
Cdd:COG3845 15 FGGVVANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQ-----PDSGEILIDGKPV-RIRSPRDAIALGIGMVHQH 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 126 PNPFPK-SIYDNITYG---PKIHGIKNKKVLDEIVEKSLR-------GAAIWDelkdrlhtnaysLSGGQQQRVCIARCL 194
Cdd:COG3845 89 FMLVPNlTVAENIVLGlepTKGGRLDRKAARARIRELSERygldvdpDAKVED------------LSVGEQQRVEILKAL 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 580041203 195 AIEPEVILMDEPTSALDPISTLRVEELVQELKEK-YTIIMVTHNMQQAARVSDK 247
Cdd:COG3845 157 YRGARILILDEPTAVLTPQEADELFEILRRLAAEgKSIIFITHKLREVMAIADR 210
|
|
| ssuB |
PRK11247 |
aliphatic sulfonates transport ATP-binding subunit; Provisional |
46-247 |
2.80e-23 |
|
aliphatic sulfonates transport ATP-binding subunit; Provisional
Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 95.51 E-value: 2.80e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 46 YGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILYRDQDIfdqkyskEQLRTNVGMVFQQ 125
Cdd:PRK11247 22 YGERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLET-----PSAGELLAGTAPL-------AEAREDTRLMFQD 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 126 PNPFP-KSIYDNITYGpkihgiknkkvldeiveksLRGAaiWDE----------LKDRLHTNAYSLSGGQQQRVCIARCL 194
Cdd:PRK11247 90 ARLLPwKKVIDNVGLG-------------------LKGQ--WRDaalqalaavgLADRANEWPAALSGGQKQRVALARAL 148
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 580041203 195 AIEPEVILMDEPTSALDPISTLRVEELVQELKEKY--TIIMVTHNMQQAARVSDK 247
Cdd:PRK11247 149 IHRPGLLLLDEPLGALDALTRIEMQDLIESLWQQHgfTVLLVTHDVSEAVAMADR 203
|
|
| ABC_FeS_Assembly |
cd03217 |
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ... |
43-237 |
3.01e-23 |
|
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.
Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 94.13 E-value: 3.01e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 43 DLWY--GENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLnrMVelVPSVK-TAGKILYRDQDIFDQKYSkEQLRTNV 119
Cdd:cd03217 5 DLHVsvGGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTI--MG--HPKYEvTEGEILFKGEDITDLPPE-ERARLGI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 120 GMVFQQPnpfpksiydnitygPKIHGIKNKKVLDEIVEkslrgaaiwdelkdrlhtnaySLSGGQQQRVCIARCLAIEPE 199
Cdd:cd03217 80 FLAFQYP--------------PEIPGVKNADFLRYVNE---------------------GFSGGEKKRNEILQLLLLEPD 124
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 580041203 200 VILMDEPTSALDpISTLR-VEELVQELK-EKYTIIMVTHN 237
Cdd:cd03217 125 LAILDEPDSGLD-IDALRlVAEVINKLReEGKSVLIITHY 163
|
|
| modC_ABC |
TIGR02142 |
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ... |
49-269 |
3.11e-23 |
|
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]
Pssm-ID: 131197 [Multi-domain] Cd Length: 354 Bit Score: 97.10 E-value: 3.11e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 49 NHALqNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELvpsvkTAGKILYRDQDIFDQKySKEQL---RTNVGMVFQQ 125
Cdd:TIGR02142 11 DFSL-DADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRP-----DEGEIVLNGRTLFDSR-KGIFLppeKRRIGYVFQE 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 126 PNPFPK-SIYDNITYGPKIHGIKNKKVLDEIVEKSLrgaAIwDELKDRLhtnAYSLSGGQQQRVCIARCLAIEPEVILMD 204
Cdd:TIGR02142 84 ARLFPHlSVRGNLRYGMKRARPSERRISFERVIELL---GI-GHLLGRL---PGRLSGGEKQRVAIGRALLSSPRLLLMD 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 580041203 205 EPTSALDPISTLRV----EELVQELkeKYTIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNP 269
Cdd:TIGR02142 157 EPLAALDDPRKYEIlpylERLHAEF--GIPILYVSHSLQEVLRLADRVVVLEDGRVAAAGPIAEVWASP 223
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
46-247 |
5.96e-23 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 94.32 E-value: 5.96e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 46 YGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMveLVPS---VKTAGKILYRDqdifdqkysKEQLRTNVGMV 122
Cdd:cd03267 31 YREVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGL--LQPTsgeVRVAGLVPWKR---------RKKFLRRIGVV 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 123 FQQPN------PFPKSIYDNitygPKIHGIKN---KKVLDEIVEKSlrgaaiwdELKDRLHTNAYSLSGGQQQRVCIARC 193
Cdd:cd03267 100 FGQKTqlwwdlPVIDSFYLL----AAIYDLPParfKKRLDELSELL--------DLEELLDTPVRQLSLGQRMRAEIAAA 167
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 580041203 194 LAIEPEVILMDEPTSALDPISTLRVEELVQELKEKY--TIIMVTHNMQQAARVSDK 247
Cdd:cd03267 168 LLHEPEILFLDEPTIGLDVVAQENIRNFLKEYNRERgtTVLLTSHYMKDIEALARR 223
|
|
| cbiO |
PRK13650 |
energy-coupling factor transporter ATPase; |
48-267 |
7.74e-23 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 94.80 E-value: 7.74e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 48 ENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILyrdqdIFDQKYSKE---QLRTNVGMVFQ 124
Cdd:PRK13650 19 EKYTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLE-----AESGQII-----IDGDLLTEEnvwDIRHKIGMVFQ 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 125 QP-NPF-PKSIYDNITYGPKIHGIKNKKvLDEIVEKSLRGAAIWDeLKDRlhtNAYSLSGGQQQRVCIARCLAIEPEVIL 202
Cdd:PRK13650 89 NPdNQFvGATVEDDVAFGLENKGIPHEE-MKERVNEALELVGMQD-FKER---EPARLSGGQKQRVAIAGAVAMRPKIII 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 580041203 203 MDEPTSALDPISTLRVEELVQELKEKY--TIIMVTHNMQQAArVSDKTAFFLNGYVNEYDDTDKIFS 267
Cdd:PRK13650 164 LDEATSMLDPEGRLELIKTIKGIRDDYqmTVISITHDLDEVA-LSDRVLVMKNGQVESTSTPRELFS 229
|
|
| NHLM_micro_ABC1 |
TIGR03796 |
NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein; This protein describes ... |
48-236 |
1.28e-22 |
|
NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein; This protein describes a multidomain ABC transporter subunit that is one of three protein families associated with some regularity with a distinctive family of putative bacteriocins. It includes a bacteriocin-processing peptidase domain at the N-terminus. Model TIGR03793 describes a conserved propeptide region for this bacteriocin family, unusual because it shows obvious homology a region of the enzyme nitrile hydratase up to the classic Gly-Gly cleavage motif. This family is therefore predicted to be a subunit of a bacteriocin processing and export system characteristic to this system that we designate NHLM, Nitrile Hydratase Leader Microcin. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Biosynthesis of natural products]
Pssm-ID: 274788 [Multi-domain] Cd Length: 710 Bit Score: 97.32 E-value: 1.28e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 48 ENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvPSvktAGKILYRDQDIfdQKYSKEQLRTNVGMVFQQPN 127
Cdd:TIGR03796 491 EPPLIENFSLTLQPGQRVALVGGSGSGKSTIAKLVAGLYQ--PW---SGEILFDGIPR--EEIPREVLANSVAMVDQDIF 563
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 128 PFPKSIYDNITygpkihgIKNKKVLDEIVEKSLRGAAIWDELKDR-------LHTNAYSLSGGQQQRVCIARCLAIEPEV 200
Cdd:TIGR03796 564 LFEGTVRDNLT-------LWDPTIPDADLVRACKDAAIHDVITSRpggydaeLAEGGANLSGGQRQRLEIARALVRNPSI 636
|
170 180 190
....*....|....*....|....*....|....*..
gi 580041203 201 ILMDEPTSALDPISTLRVeelVQELKEK-YTIIMVTH 236
Cdd:TIGR03796 637 LILDEATSALDPETEKII---DDNLRRRgCTCIIVAH 670
|
|
| galliderm_ABC |
TIGR03740 |
gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 ... |
39-268 |
2.03e-22 |
|
gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 represents the family of all lantibiotics related to gallidermin, including epidermin, mutatin, and nisin. This protein family describes the ATP-binding subunit of a gallidermin/epidermin class lantibiotic protection transporter. It is largely restricted to gallidermin-family lantibiotic biosynthesis and export cassettes, but also occurs in orphan transporter cassettes in species that lack candidate lantibiotic precursor and synthetase genes.
Pssm-ID: 163452 [Multi-domain] Cd Length: 223 Bit Score: 92.46 E-value: 2.03e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 39 TQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKIlyrdqdIFD-QKYSKEQLRt 117
Cdd:TIGR03740 3 TKNLSKRFGKQTAVNNISLTVPKNSVYGLLGPNGAGKSTLLKMITGILR-----PTSGEI------IFDgHPWTRKDLH- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 118 NVGMVFQQPNPFPK-SIYDNITYGPKIHGIKNKKVlDEIVEKSlrgaaiwdELKDRLHTNAYSLSGGQQQRVCIARCLAI 196
Cdd:TIGR03740 71 KIGSLIESPPLYENlTARENLKVHTTLLGLPDSRI-DEVLNIV--------DLTNTGKKKAKQFSLGMKQRLGIAIALLN 141
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 580041203 197 EPEVILMDEPTSALDPISTLRVEELVQELKEK-YTIIMVTHNMQQAARVSDKTAFFLNGY------VNEYDDTDKIFSN 268
Cdd:TIGR03740 142 HPKLLILDEPTNGLDPIGIQELRELIRSFPEQgITVILSSHILSEVQQLADHIGIISEGVlgyqgkINKSENLEKLFVE 220
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
51-239 |
2.16e-22 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 91.76 E-value: 2.16e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 51 ALQNINLDIYENQITAIIGPSGCGKSTYIKTLnrMVELVpsvKTAGKIlyrdqdifdqkyskeQLRTNVGMVFQQPNPFP 130
Cdd:cd03250 20 TLKDINLEVPKGELVAIVGPVGSGKSSLLSAL--LGELE---KLSGSV---------------SVPGSIAYVSQEPWIQN 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 131 KSIYDNITYGpkihgiknkKVLD-EIVEKSLRGAAI---WDELKDRLHT----NAYSLSGGQQQRVCIARCLAIEPEVIL 202
Cdd:cd03250 80 GTIRENILFG---------KPFDeERYEKVIKACALepdLEILPDGDLTeigeKGINLSGGQKQRISLARAVYSDADIYL 150
|
170 180 190
....*....|....*....|....*....|....*....
gi 580041203 203 MDEPTSALDP-ISTLRVEELVQ-ELKEKYTIIMVTHNMQ 239
Cdd:cd03250 151 LDDPLSAVDAhVGRHIFENCILgLLLNNKTRILVTHQLQ 189
|
|
| cbiO |
PRK13642 |
energy-coupling factor transporter ATPase; |
36-242 |
2.46e-22 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 93.62 E-value: 2.46e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 36 IYSTQNLDLWYGEN---HALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELVPS-VKTAGKILyRDQDIFDqkys 111
Cdd:PRK13642 4 ILEVENLVFKYEKEsdvNQLNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGkVKIDGELL-TAENVWN---- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 112 keqLRTNVGMVFQQP-NPF-PKSIYDNITYGPKIHGIKNKKVLDEiVEKSLRGAAIWDeLKDRlhtNAYSLSGGQQQRVC 189
Cdd:PRK13642 79 ---LRRKIGMVFQNPdNQFvGATVEDDVAFGMENQGIPREEMIKR-VDEALLAVNMLD-FKTR---EPARLSGGQKQRVA 150
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 580041203 190 IARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEKY--TIIMVTHNMQQAA 242
Cdd:PRK13642 151 VAGIIALRPEIIILDESTSMLDPTGRQEIMRVIHEIKEKYqlTVLSITHDLDEAA 205
|
|
| modC |
PRK11144 |
molybdenum ABC transporter ATP-binding protein ModC; |
49-269 |
3.37e-22 |
|
molybdenum ABC transporter ATP-binding protein ModC;
Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 94.17 E-value: 3.37e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 49 NHALQnINLDIYENQITAIIGPSGCGKSTYIktlNRMVELVpsVKTAGKILYRDQDIFDQkYSKEQL---RTNVGMVFQQ 125
Cdd:PRK11144 12 DLCLT-VNLTLPAQGITAIFGRSGAGKTSLI---NAISGLT--RPQKGRIVLNGRVLFDA-EKGICLppeKRRIGYVFQD 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 126 PNPFPK-SIYDNITYGPKIhgiKNKKVLDEIVEksLRGAaiwDELKDRLhtnAYSLSGGQQQRVCIARCLAIEPEVILMD 204
Cdd:PRK11144 85 ARLFPHyKVRGNLRYGMAK---SMVAQFDKIVA--LLGI---EPLLDRY---PGSLSGGEKQRVAIGRALLTAPELLLMD 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 580041203 205 EPTSALD-PistlRVEELV---QELKE--KYTIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNP 269
Cdd:PRK11144 154 EPLASLDlP----RKRELLpylERLAReiNIPILYVSHSLDEILRLADRVVVLEQGKVKAFGPLEEVWASS 220
|
|
| oppD |
PRK09473 |
oligopeptide transporter ATP-binding component; Provisional |
20-270 |
4.54e-22 |
|
oligopeptide transporter ATP-binding component; Provisional
Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 93.64 E-value: 4.54e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 20 SQSHHKTPDDTNSHSVIYSTQNldlwyGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLnrMVELVPSVKTAGKIL 99
Cdd:PRK09473 5 AQQQADALLDVKDLRVTFSTPD-----GDVTAVNDLNFSLRAGETLGIVGESGSGKSQTAFAL--MGLLAANGRIGGSAT 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 100 YRDQDIFDQKYSK-EQLRT-NVGMVFQQP----NPFPKsIYDNITYGPKIHGIKNKKvldEIVEKSLR--GAAIWDELKD 171
Cdd:PRK09473 78 FNGREILNLPEKElNKLRAeQISMIFQDPmtslNPYMR-VGEQLMEVLMLHKGMSKA---EAFEESVRmlDAVKMPEARK 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 172 RLHTNAYSLSGGQQQRVCIARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEKY--TIIMVTHNMQQAARVSDKTA 249
Cdd:PRK09473 154 RMKMYPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFntAIIMITHDLGVVAGICDKVL 233
|
250 260
....*....|....*....|.
gi 580041203 250 FFLNGYVNEYDDTDKIFSNPS 270
Cdd:PRK09473 234 VMYAGRTMEYGNARDVFYQPS 254
|
|
| CP_lyasePhnK |
TIGR02323 |
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P ... |
36-279 |
4.54e-22 |
|
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated complex. This protein (PhnK) and the adjacent-encoded PhnL resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this complex rather than part of a transporter per se. [Central intermediary metabolism, Phosphorus compounds]
Pssm-ID: 188208 [Multi-domain] Cd Length: 253 Bit Score: 92.20 E-value: 4.54e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 36 IYSTQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNrmVELVPSvktAGKILYRDQD-----IFDQKY 110
Cdd:TIGR02323 3 LLQVSGLSKSYGGGKGCRDVSFDLYPGEVLGIVGESGSGKSTLLGCLA--GRLAPD---HGTATYIMRSgaeleLYQLSE 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 111 SKEQ--LRTNVGMVFQQPNPFPK---SIYDNITYGPKIHGIKNKKVLDEIVEKSLRGAAIwdeLKDRLHTNAYSLSGGQQ 185
Cdd:TIGR02323 78 AERRrlMRTEWGFVHQNPRDGLRmrvSAGANIGERLMAIGARHYGNIRATAQDWLEEVEI---DPTRIDDLPRAFSGGMQ 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 186 QRVCIARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEKYTI--IMVTHNMQQAARVSDKTAFFLNGYVNEYDDTD 263
Cdd:TIGR02323 155 QRLQIARNLVTRPRLVFMDEPTGGLDVSVQARLLDLLRGLVRDLGLavIIVTHDLGVARLLAQRLLVMQQGRVVESGLTD 234
|
250
....*....|....*.
gi 580041203 264 KIFSNPSNKKTEDYIS 279
Cdd:TIGR02323 235 QVLDDPQHPYTQLLVS 250
|
|
| dppF |
PRK11308 |
dipeptide transporter ATP-binding subunit; Provisional |
66-269 |
4.88e-22 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 93.49 E-value: 4.88e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 66 AIIGPSGCGKSTyiktLNRMVELVpSVKTAGKILYRDQDIFdqKYSKE---QLRTNVGMVFQQPnpfpksiydnitYG-- 140
Cdd:PRK11308 45 AVVGESGCGKST----LARLLTMI-ETPTGGELYYQGQDLL--KADPEaqkLLRQKIQIVFQNP------------YGsl 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 141 -PKihgiknKKVlDEIVEKSLR-----GAAiwdELKDRL------------HTNAYS--LSGGQQQRVCIARCLAIEPEV 200
Cdd:PRK11308 106 nPR------KKV-GQILEEPLLintslSAA---ERREKAlammakvglrpeHYDRYPhmFSGGQRQRIAIARALMLDPDV 175
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 580041203 201 ILMDEPTSALDpIStLRVE------ELVQELKEKYTIImvTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNP 269
Cdd:PRK11308 176 VVADEPVSALD-VS-VQAQvlnlmmDLQQELGLSYVFI--SHDLSVVEHIADEVMVMYLGRCVEKGTKEQIFNNP 246
|
|
| PRK11160 |
PRK11160 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
40-237 |
5.65e-22 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 95.28 E-value: 5.65e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWY--GENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRmvELVPsvkTAGKILYRDQDIfdQKYSKEQLRT 117
Cdd:PRK11160 342 NNVSFTYpdQPQPVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTR--AWDP---QQGEILLNGQPI--ADYSEAALRQ 414
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 118 NVGMVFQQPNPFPKSIYDNITygpkihgIKNKKVLDEIVEKSLRGAAIWDELKDRLHTNAY------SLSGGQQQRVCIA 191
Cdd:PRK11160 415 AISVVSQRVHLFSATLRDNLL-------LAAPNASDEALIEVLQQVGLEKLLEDDKGLNAWlgeggrQLSGGEQRRLGIA 487
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 580041203 192 RCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEKYTIIMVTHN 237
Cdd:PRK11160 488 RALLHDAPLLLLDEPTEGLDAETERQILELLAEHAQNKTVLMITHR 533
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
40-260 |
6.72e-22 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 90.55 E-value: 6.72e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGEN--HALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELvpsvkTAGKILYRDQDIfdQKYSKEQLRT 117
Cdd:cd03369 10 ENLSVRYAPDlpPVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEA-----EEGKIEIDGIDI--STIPLEDLRS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 118 NVGMVFQQPNPFPKSIYDNItygpkihgiknkKVLDEIVEKSLRGAAiwdelkdRLHTNAYSLSGGQQQRVCIARCLAIE 197
Cdd:cd03369 83 SLTIIPQDPTLFSGTIRSNL------------DPFDEYSDEEIYGAL-------RVSEGGLNLSQGQRQLLCLARALLKR 143
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 580041203 198 PEVILMDEPTSALDPISTLRVEELVQELKEKYTIIMVTHNMQQAARVsDKTAFFLNGYVNEYD 260
Cdd:cd03369 144 PRVLVLDEATASIDYATDALIQKTIREEFTNSTILTIAHRLRTIIDY-DKILVMDAGEVKEYD 205
|
|
| PRK10535 |
PRK10535 |
macrolide ABC transporter ATP-binding protein/permease MacB; |
52-244 |
6.85e-22 |
|
macrolide ABC transporter ATP-binding protein/permease MacB;
Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 95.18 E-value: 6.85e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 52 LQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvPSVKTAgKILYRDQDIFDQKYSKEQLRTNVGMVFQQPNPFPK 131
Cdd:PRK10535 24 LKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDK--PTSGTY-RVAGQDVATLDADALAQLRREHFGFIFQRYHLLSH 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 132 -SIYDNITYgPKIH-GIKNKKVLDEIVEKSLRGAaiwdeLKDRLHTNAYSLSGGQQQRVCIARCLAIEPEVILMDEPTSA 209
Cdd:PRK10535 101 lTAAQNVEV-PAVYaGLERKQRLLRAQELLQRLG-----LEDRVEYQPSQLSGGQQQRVSIARALMNGGQVILADEPTGA 174
|
170 180 190
....*....|....*....|....*....|....*....
gi 580041203 210 LDPISTLRVEELVQELKEK-YTIIMVTHNMQ---QAARV 244
Cdd:PRK10535 175 LDSHSGEEVMAILHQLRDRgHTVIIVTHDPQvaaQAERV 213
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
54-275 |
8.50e-22 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 94.77 E-value: 8.50e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 54 NINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELVPSVKTAGKILYRDQDIFDQkySKEQLR----TNVGMVFQQP--- 126
Cdd:PRK15134 27 DVSLQIEAGETLALVGESGSGKSVTALSILRLLPSPPVVYPSGDIRFHGESLLHA--SEQTLRgvrgNKIAMIFQEPmvs 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 127 -NPF---PKSIYDNITygpkIH-GIKNKKVLDEIVE----KSLRGAAiwdelkDRLHTNAYSLSGGQQQRVCIARCLAIE 197
Cdd:PRK15134 105 lNPLhtlEKQLYEVLS----LHrGMRREAARGEILNcldrVGIRQAA------KRLTDYPHQLSGGERQRVMIAMALLTR 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 198 PEVILMDEPTSALDPISTLRVEELVQELKEKYTIIM--VTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNPSNKKTE 275
Cdd:PRK15134 175 PELLIADEPTTALDVSVQAQILQLLRELQQELNMGLlfITHNLSIVRKLADRVAVMQNGRCVEQNRAATLFSAPTHPYTQ 254
|
|
| nikE |
PRK10419 |
nickel ABC transporter ATP-binding protein NikE; |
34-238 |
9.30e-22 |
|
nickel ABC transporter ATP-binding protein NikE;
Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 91.67 E-value: 9.30e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 34 SVIYSTQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTyiktLNRMveLVPSVK-TAGKILYRDQDIfdQKYSK 112
Cdd:PRK10419 10 SHHYAHGGLSGKHQHQTVLNNVSLSLKSGETVALLGRSGCGKST----LARL--LVGLESpSQGNVSWRGEPL--AKLNR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 113 EQLRT---NVGMVFQQP----NPfPKSIYDnITYGPKIHGIKnkkvLDEI-----VEKSLRGAAIWDELKDRLHTnaySL 180
Cdd:PRK10419 82 AQRKAfrrDIQMVFQDSisavNP-RKTVRE-IIREPLRHLLS----LDKAerlarASEMLRAVDLDDSVLDKRPP---QL 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 181 SGGQQQRVCIARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEKYTI--IMVTHNM 238
Cdd:PRK10419 153 SGGQLQRVCLARALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQFGTacLFITHDL 212
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
56-253 |
1.35e-21 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 94.71 E-value: 1.35e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 56 NLDIYEN--------QITAIIGPSGCGKSTYIKTLNRMVEL--------------------------------------- 88
Cdd:PTZ00265 1180 NVPIYKDltfscdskKTTAIVGETGSGKSTVMSLLMRFYDLkndhhivfknehtndmtneqdyqgdeeqnvgmknvnefs 1259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 89 ----------VPSVKTAGKILYRDQDIFDqkYSKEQLRTNVGMVFQQPNPFPKSIYDNITYGpkihgikNKKVLDEIVEK 158
Cdd:PTZ00265 1260 ltkeggsgedSTVFKNSGKILLDGVDICD--YNLKDLRNLFSIVSQEPMLFNMSIYENIKFG-------KEDATREDVKR 1330
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 159 SLRGAAIwDE----LKDRLHTN----AYSLSGGQQQRVCIARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEKY- 229
Cdd:PTZ00265 1331 ACKFAAI-DEfiesLPNKYDTNvgpyGKSLSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIEKTIVDIKDKAd 1409
|
250 260
....*....|....*....|....*
gi 580041203 230 -TIIMVTHNMQQAARvSDKTAFFLN 253
Cdd:PTZ00265 1410 kTIITIAHRIASIKR-SDKIVVFNN 1433
|
|
| YbbA |
COG4181 |
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ... |
32-243 |
1.57e-21 |
|
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443338 [Multi-domain] Cd Length: 233 Bit Score: 90.19 E-value: 1.57e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 32 SHSVIySTQNLDLWYGEN----HALQNINLDIYENQITAIIGPSGCGKSTYiktLNRMVEL-VPsvkTAGKILYRDQDIF 106
Cdd:COG4181 5 SAPII-ELRGLTKTVGTGagelTILKGISLEVEAGESVAIVGASGSGKSTL---LGLLAGLdRP---TSGTVRLAGQDLF 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 107 dqKYSKEQL----RTNVGMVFQQpnpFpksiydnitygpkiHGIKNKKVLDEI---VEksLRG-------AAIWDE---L 169
Cdd:COG4181 78 --ALDEDARarlrARHVGFVFQS---F--------------QLLPTLTALENVmlpLE--LAGrrdararARALLErvgL 136
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 580041203 170 KDRLHtnAY--SLSGGQQQRVCIARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEKY--TIIMVTHNMQQAAR 243
Cdd:COG4181 137 GHRLD--HYpaQLSGGEQQRVALARAFATEPAILFADEPTGNLDAATGEQIIDLLFELNRERgtTLVLVTHDPALAAR 212
|
|
| PRK15112 |
PRK15112 |
peptide ABC transporter ATP-binding protein SapF; |
45-283 |
3.02e-21 |
|
peptide ABC transporter ATP-binding protein SapF;
Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 90.23 E-value: 3.02e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 45 WYGENH--ALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILYRDQDIF--DQKYSKEQLRtnvg 120
Cdd:PRK15112 20 WFRRQTveAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIE-----PTSGELLIDDHPLHfgDYSYRSQRIR---- 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 121 MVFQQPNPF--PKSIYDNITYGPKIhgiknkkvLDEIVEKSLRGAAIWDELKD----RLHTNAYS--LSGGQQQRVCIAR 192
Cdd:PRK15112 91 MIFQDPSTSlnPRQRISQILDFPLR--------LNTDLEPEQREKQIIETLRQvgllPDHASYYPhmLAPGQKQRLGLAR 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 193 CLAIEPEVILMDEPTSALDPISTLRVEELVQELKEKYTI--IMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNPS 270
Cdd:PRK15112 163 ALILRPKVIIADEALASLDMSMRSQLINLMLELQEKQGIsyIYVTQHLGMMKHISDQVLVMHQGEVVERGSTADVLASPL 242
|
250
....*....|...
gi 580041203 271 NKKTEDYISGRFG 283
Cdd:PRK15112 243 HELTKRLIAGHFG 255
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
46-241 |
5.00e-21 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 89.37 E-value: 5.00e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 46 YGENHALQNINLDIYENQITAIIGPSGCGKSTYiktLNRMVELVPSvkTAGKILYRDQDIfdQKYSKEQlrtnvGMVFQQ 125
Cdd:PRK11248 11 YGGKPALEDINLTLESGELLVVLGPSGCGKTTL---LNLIAGFVPY--QHGSITLDGKPV--EGPGAER-----GVVFQN 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 126 PNPFP-KSIYDNITYGPKIHGI---KNKKVLDEIVEK-SLRGAA---IWdelkdrlhtnaySLSGGQQQRVCIARCLAIE 197
Cdd:PRK11248 79 EGLLPwRNVQDNVAFGLQLAGVekmQRLEIAHQMLKKvGLEGAEkryIW------------QLSGGQRQRVGIARALAAN 146
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 580041203 198 PEVILMDEPTSALDPISTLRVEELVQEL--KEKYTIIMVTHNMQQA 241
Cdd:PRK11248 147 PQLLLLDEPFGALDAFTREQMQTLLLKLwqETGKQVLLITHDIEEA 192
|
|
| CeuD |
COG4604 |
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ... |
38-246 |
7.37e-21 |
|
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443654 [Multi-domain] Cd Length: 252 Bit Score: 88.99 E-value: 7.37e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 38 STQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTyikTLNRMVELVPsvKTAGKILYRDQDIFDQKysKEQLRT 117
Cdd:COG4604 3 EIKNVSKRYGGKVVLDDVSLTIPKGGITALIGPNGAGKST---LLSMISRLLP--PDSGEVLVDGLDVATTP--SRELAK 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 118 NVGmVFQQPNPFPK--SIYDNITYG--PKIHGIKNKKvlD-EIVEKSLRGAAIwDELKDR-LHTnaysLSGGQQQRVCIA 191
Cdd:COG4604 76 RLA-ILRQENHINSrlTVRELVAFGrfPYSKGRLTAE--DrEIIDEAIAYLDL-EDLADRyLDE----LSGGQRQRAFIA 147
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 580041203 192 RCLAIEPEVILMDEPTSALDP------ISTLRveELVQELKEkyTIIMVTHNMQQAARVSD 246
Cdd:COG4604 148 MVLAQDTDYVLLDEPLNNLDMkhsvqmMKLLR--RLADELGK--TVVIVLHDINFASCYAD 204
|
|
| ATM1 |
COG5265 |
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ... |
52-211 |
7.97e-21 |
|
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444078 [Multi-domain] Cd Length: 605 Bit Score: 91.81 E-value: 7.97e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 52 LQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELvpsvkTAGKILYRDQDIfdQKYSKEQLRTNVGMVFQQPNPFPK 131
Cdd:COG5265 374 LKGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDV-----TSGRILIDGQDI--RDVTQASLRAAIGIVPQDTVLFND 446
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 132 SIYDNITYGpkihgikNKKVLDEIVEKSLRGAAIWD---ELKDRLHTN----AYSLSGGQQQRVCIARCLAIEPEVILMD 204
Cdd:COG5265 447 TIAYNIAYG-------RPDASEEEVEAAARAAQIHDfieSLPDGYDTRvgerGLKLSGGEKQRVAIARTLLKNPPILIFD 519
|
....*..
gi 580041203 205 EPTSALD 211
Cdd:COG5265 520 EATSALD 526
|
|
| AztA |
NF040873 |
zinc ABC transporter ATP-binding protein AztA; |
46-243 |
8.35e-21 |
|
zinc ABC transporter ATP-binding protein AztA;
Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 87.29 E-value: 8.35e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 46 YGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMveLVPsvkTAGKILYRDqdifdqkyskeqlRTNVGMVFQQ 125
Cdd:NF040873 2 YGGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGV--LRP---TSGTVRRAG-------------GARVAYVPQR 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 126 ---PNPFPKSIYDNITYG--PKIHGIKNKKVLDE-IVEKSLRGAAIWDELKDRLHTnaysLSGGQQQRVCIARCLAIEPE 199
Cdd:NF040873 64 sevPDSLPLTVRDLVAMGrwARRGLWRRLTRDDRaAVDDALERVGLADLAGRQLGE----LSGGQRQRALLAQGLAQEAD 139
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 580041203 200 VILMDEPTSALDPISTLRVEELVQEL-KEKYTIIMVTHNMQQAAR 243
Cdd:NF040873 140 LLLLDEPTTGLDAESRERIIALLAEEhARGATVVVVTHDLELVRR 184
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
51-254 |
1.26e-20 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 91.61 E-value: 1.26e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 51 ALQNINLDIYENQITAIIGPSGCGKSTyikTLNRMVELVPSvkTAGKILYRDQDIfdqKYSKEQLRTNVGMVFQQPNPFP 130
Cdd:TIGR01257 945 AVDRLNITFYENQITAFLGHNGAGKTT---TLSILTGLLPP--TSGTVLVGGKDI---ETNLDAVRQSLGMCPQHNILFH 1016
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 131 K-SIYDNITYGPKIHGIKNKkvldeivEKSLRGAAIWDE--LKDRLHTNAYSLSGGQQQRVCIARCLAIEPEVILMDEPT 207
Cdd:TIGR01257 1017 HlTVAEHILFYAQLKGRSWE-------EAQLEMEAMLEDtgLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPT 1089
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 580041203 208 SALDPISTLRVEELVQELKEKYTIIMVTHNMQQAARVSDKTAFFLNG 254
Cdd:TIGR01257 1090 SGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGDRIAIISQG 1136
|
|
| PRK11174 |
PRK11174 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
52-240 |
1.92e-20 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 90.67 E-value: 1.92e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 52 LQNINLDIYENQITAIIGPSGCGKSTYiktLNRMVELVP---SVKTAGKILyRDQDifdqkysKEQLRTNVGMVFQQPNP 128
Cdd:PRK11174 366 AGPLNFTLPAGQRIALVGPSGAGKTSL---LNALLGFLPyqgSLKINGIEL-RELD-------PESWRKHLSWVGQNPQL 434
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 129 FPKSIYDNITYGpkihgikNKKVLDEIVEKSLRGAAIWD---ELKDRLHT----NAYSLSGGQQQRVCIARCLAIEPEVI 201
Cdd:PRK11174 435 PHGTLRDNVLLG-------NPDASDEQLQQALENAWVSEflpLLPQGLDTpigdQAAGLSVGQAQRLALARALLQPCQLL 507
|
170 180 190
....*....|....*....|....*....|....*....
gi 580041203 202 LMDEPTSALDPISTLRVEELVQELKEKYTIIMVTHNMQQ 240
Cdd:PRK11174 508 LLDEPTASLDAHSEQLVMQALNAASRRQTTLMVTHQLED 546
|
|
| PRK11831 |
PRK11831 |
phospholipid ABC transporter ATP-binding protein MlaF; |
47-246 |
2.52e-20 |
|
phospholipid ABC transporter ATP-binding protein MlaF;
Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 87.90 E-value: 2.52e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 47 GENHALQNINLDIYENQITAIIGPSGCGKSTyiktLNRMV--ELVPSvktAGKILYRDQDIfdQKYSKEQL---RTNVGM 121
Cdd:PRK11831 18 GNRCIFDNISLTVPRGKITAIMGPSGIGKTT----LLRLIggQIAPD---HGEILFDGENI--PAMSRSRLytvRKRMSM 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 122 VFQQPNPFPK-SIYDNITYGPKIHG-----IKNKKVLDEIVEKSLRGAAiwdELKDRlhtnaySLSGGQQQRVCIARCLA 195
Cdd:PRK11831 89 LFQSGALFTDmNVFDNVAYPLREHTqlpapLLHSTVMMKLEAVGLRGAA---KLMPS------ELSGGMARRAALARAIA 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 580041203 196 IEPEVILMDEPTSALDPISTLRVEELVQELKEKY--TIIMVTHNMQQAARVSD 246
Cdd:PRK11831 160 LEPDLIMFDEPFVGQDPITMGVLVKLISELNSALgvTCVVVSHDVPEVLSIAD 212
|
|
| livG |
PRK11300 |
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional |
51-247 |
2.75e-20 |
|
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 87.35 E-value: 2.75e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 51 ALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILYRDQDIfdQKYSKEQLrTNVGMV--FQQPNP 128
Cdd:PRK11300 20 AVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYK-----PTGGTILLRGQHI--EGLPGHQI-ARMGVVrtFQHVRL 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 129 FPK-SIYDNITYGPK-------IHGIKNKKVLDEIVEKSLRGAAIWDE---LKDRLHTNAYSLSGGQQQRVCIARCLAIE 197
Cdd:PRK11300 92 FREmTVIENLLVAQHqqlktglFSGLLKTPAFRRAESEALDRAATWLErvgLLEHANRQAGNLAYGQQRRLEIARCMVTQ 171
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 580041203 198 PEVILMDEPTSALDPISTLRVEELVQELKEKY--TIIMVTHNMQQAARVSDK 247
Cdd:PRK11300 172 PEILMLDEPAAGLNPKETKELDELIAELRNEHnvTVLLIEHDMKLVMGISDR 223
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
27-260 |
3.01e-20 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 90.12 E-value: 3.01e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 27 PDDTNSHSVIYSTQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRmvELVPsvkTAGKIL------- 99
Cdd:COG0488 306 PPPERLGKKVLELEGLSKSYGDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAG--ELEP---DSGTVKlgetvki 380
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 100 -YrdqdiFDQKYskEQLRTNvgmvfqqpnpfpKSIYDNITYGpkihgiknkkvLDEIVEKSLRGAaiwdeLK------DR 172
Cdd:COG0488 381 gY-----FDQHQ--EELDPD------------KTVLDELRDG-----------APGGTEQEVRGY-----LGrflfsgDD 425
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 173 LHTNAYSLSGGQQQRVCIARCLAIEPEVILMDEPTSALDpISTLRV-EELVQElkekY--TIIMVTHNMQQAARVSDKTA 249
Cdd:COG0488 426 AFKPVGVLSGGEKARLALAKLLLSPPNVLLLDEPTNHLD-IETLEAlEEALDD----FpgTVLLVSHDRYFLDRVATRIL 500
|
250
....*....|.
gi 580041203 250 FFLNGYVNEYD 260
Cdd:COG0488 501 EFEDGGVREYP 511
|
|
| PhnL |
COG4778 |
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ... |
51-248 |
5.25e-20 |
|
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];
Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 85.95 E-value: 5.25e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 51 ALQNINLDIYENQITAIIGPSGCGKSTYIKTLNR--MVelvpsvkTAGKILYRDQ----DIfdQKYSKEQL----RTNVG 120
Cdd:COG4778 26 VLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGnyLP-------DSGSILVRHDggwvDL--AQASPREIlalrRRTIG 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 121 MVFQqpnpFPKSIydnitygPKIHGIknkkvldEIVEKSLRGAAIWDE--------------LKDRLHTNAYS-LSGGQQ 185
Cdd:COG4778 97 YVSQ----FLRVI-------PRVSAL-------DVVAEPLLERGVDREearararellarlnLPERLWDLPPAtFSGGEQ 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 580041203 186 QRVCIARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEKYT-IIMVTHNMQQAARVSDKT 248
Cdd:COG4778 159 QRVNIARGFIADPPLLLLDEPTASLDAANRAVVVELIEEAKARGTaIIGIFHDEEVREAVADRV 222
|
|
| TagH |
COG1134 |
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ... |
46-265 |
6.07e-20 |
|
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 86.29 E-value: 6.07e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 46 YGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvP---SVKTAGKI---LyrdqdifdqkyskeqlrtNV 119
Cdd:COG1134 36 REEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILE--PtsgRVEVNGRVsalL------------------EL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 120 GMVFQqpnpfPK-SIYDNITYGPKIHGIKNK---KVLDEIVEKSlrgaaiwdELKDRLHTNAYSLSGGQQQRVCIARCLA 195
Cdd:COG1134 96 GAGFH-----PElTGRENIYLNGRLLGLSRKeidEKFDEIVEFA--------ELGDFIDQPVKTYSSGMRARLAFAVATA 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 580041203 196 IEPEVILMDEPTSALDPISTLRVEELVQELKEKY-TIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKI 265
Cdd:COG1134 163 VDPDILLVDEVLAVGDAAFQKKCLARIRELRESGrTVIFVSHSMGAVRRLCDRAIWLEKGRLVMDGDPEEV 233
|
|
| PRK10908 |
PRK10908 |
cell division ATP-binding protein FtsE; |
45-243 |
6.48e-20 |
|
cell division ATP-binding protein FtsE;
Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 85.70 E-value: 6.48e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 45 WYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvPSvktAGKILYRDQDIFDQKYSKEQ-LRTNVGMVF 123
Cdd:PRK10908 11 YLGGRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIER--PS---AGKIWFSGHDITRLKNREVPfLRRQIGMIF 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 124 QQPNPF-PKSIYDNITYGPKIHGIKNKKVldeivekSLRGAAIWDE--LKDRLHTNAYSLSGGQQQRVCIARCLAIEPEV 200
Cdd:PRK10908 86 QDHHLLmDRTVYDNVAIPLIIAGASGDDI-------RRRVSAALDKvgLLDKAKNFPIQLSGGEQQRVGIARAVVNKPAV 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 580041203 201 ILMDEPTSALDPISTLRVEELVQELKE-KYTIIMVTHNMQQAAR 243
Cdd:PRK10908 159 LLADEPTGNLDDALSEGILRLFEEFNRvGVTVLMATHDIGLISR 202
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
28-275 |
7.03e-20 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 89.14 E-value: 7.03e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 28 DDTNSHSVIySTQNLDLWYGENH----ALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELVPSVKTAGKILYR-- 101
Cdd:PRK10261 5 DELDARDVL-AVENLNIAFMQEQqkiaAVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQAGGLVQCDKMLLRrr 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 102 -DQDIFDQKYSKEQLR----TNVGMVFQQP----NP-FPksIYDNITYGPKIH-GIKNKKVLDEiVEKSLRGAAIwDELK 170
Cdd:PRK10261 84 sRQVIELSEQSAAQMRhvrgADMAMIFQEPmtslNPvFT--VGEQIAESIRLHqGASREEAMVE-AKRMLDQVRI-PEAQ 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 171 DRLHTNAYSLSGGQQQRVCIARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEKYT--IIMVTHNMQQAARVSDKT 248
Cdd:PRK10261 160 TILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEMSmgVIFITHDMGVVAEIADRV 239
|
250 260
....*....|....*....|....*..
gi 580041203 249 AFFLNGYVNEYDDTDKIFSNPSNKKTE 275
Cdd:PRK10261 240 LVMYQGEAVETGSVEQIFHAPQHPYTR 266
|
|
| COG4586 |
COG4586 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
46-239 |
1.00e-19 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 87.06 E-value: 1.00e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 46 YGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMveLVPS---VKTAGKILYRDQdifdqkyskEQLRTNVGMV 122
Cdd:COG4586 32 YREVEAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGI--LVPTsgeVRVLGYVPFKRR---------KEFARRIGVV 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 123 FQQpnpfpKS-------IYDNITYGPKIHGIKN---KKVLDEIVEKsLrgaaiwdELKDRLHTNAYSLSGGQQQRVCIAR 192
Cdd:COG4586 101 FGQ-----RSqlwwdlpAIDSFRLLKAIYRIPDaeyKKRLDELVEL-L-------DLGELLDTPVRQLSLGQRMRCELAA 167
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 580041203 193 CLAIEPEVILMDEPTSALDPISTLRVEELVQELKEKY--TIIMVTHNMQ 239
Cdd:COG4586 168 ALLHRPKILFLDEPTIGLDVVSKEAIREFLKEYNRERgtTILLTSHDMD 216
|
|
| PRK09984 |
PRK09984 |
phosphonate ABC transporter ATP-binding protein; |
36-268 |
1.05e-19 |
|
phosphonate ABC transporter ATP-binding protein;
Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 86.22 E-value: 1.05e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 36 IYSTQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRM----------VELV-PSVKTAGKILyrdQD 104
Cdd:PRK09984 4 IIRVEKLAKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLitgdksagshIELLgRTVQREGRLA---RD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 105 IfdqkyskEQLRTNVGMVFQQPNPFPK-SIYDNITYGPK------------IHGIKNKKVLDEIVEKSLRGAAiwdelkd 171
Cdd:PRK09984 81 I-------RKSRANTGYIFQQFNLVNRlSVLENVLIGALgstpfwrtcfswFTREQKQRALQALTRVGMVHFA------- 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 172 rlHTNAYSLSGGQQQRVCIARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEK--YTIIMVTHNMQQAARVSDKTA 249
Cdd:PRK09984 147 --HQRVSTLSGGQQQRVAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNdgITVVVTLHQVDYALRYCERIV 224
|
250
....*....|....*....
gi 580041203 250 FFLNGYVNeYDDTDKIFSN 268
Cdd:PRK09984 225 ALRQGHVF-YDGSSQQFDN 242
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
47-274 |
1.06e-19 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 88.61 E-value: 1.06e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 47 GENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRmveLVPSvktAGKILYRDQDIfdQKYSKEQL---RTNVGMVF 123
Cdd:PRK15134 297 DHNVVVKNISFTLRPGETLGLVGESGSGKSTTGLALLR---LINS---QGEIWFDGQPL--HNLNRRQLlpvRHRIQVVF 368
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 124 QQPNPF--PK-SIYDNITYGPKIHGIK-NKKVLDEIVEKSLRGAAIWDELKDRLHTnaySLSGGQQQRVCIARCLAIEPE 199
Cdd:PRK15134 369 QDPNSSlnPRlNVLQIIEEGLRVHQPTlSAAQREQQVIAVMEEVGLDPETRHRYPA---EFSGGQRQRIAIARALILKPS 445
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 580041203 200 VILMDEPTSALDPISTLRVEELVQELKEKYTI--IMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNPSNKKT 274
Cdd:PRK15134 446 LIILDEPTSSLDKTVQAQILALLKSLQQKHQLayLFISHDLHVVRALCHQVIVLRQGEVVEQGDCERVFAAPQQEYT 522
|
|
| ABC_KpsT_Wzt |
cd03220 |
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ... |
46-260 |
1.20e-19 |
|
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.
Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 84.89 E-value: 1.20e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 46 YGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMveLVPS---VKTAGKILYrdqdifdqkyskeQLRTNVGMv 122
Cdd:cd03220 32 VGEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGI--YPPDsgtVTVRGRVSS-------------LLGLGGGF- 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 123 fqQPNpfpKSIYDNITYGPKIHGIKNK---KVLDEIVEKSlrgaaiwdELKDRLHTNAYSLSGGQQQRVCIARCLAIEPE 199
Cdd:cd03220 96 --NPE---LTGRENIYLNGRLLGLSRKeidEKIDEIIEFS--------ELGDFIDLPVKTYSSGMKARLAFAIATALEPD 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 580041203 200 VILMDEPTSALDPISTLRVEELVQELKEKY-TIIMVTHNMQQAARVSDKTAFFLNGYVNEYD 260
Cdd:cd03220 163 ILLIDEVLAVGDAAFQEKCQRRLRELLKQGkTVILVSHDPSSIKRLCDRALVLEKGKIRFDG 224
|
|
| cbiO |
PRK13638 |
energy-coupling factor ABC transporter ATP-binding protein; |
43-267 |
1.47e-19 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 85.83 E-value: 1.47e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 43 DLW--YGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMveLVPSvktAGKILYRDQDIfdqKYSKE---QLRT 117
Cdd:PRK13638 6 DLWfrYQDEPVLKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGL--LRPQ---KGAVLWQGKPL---DYSKRgllALRQ 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 118 NVGMVFQQPNP--FPKSIYDNITYGPKIHGIKNkkvlDEIVEKSLRGAAIWDELKDRlHTNAYSLSGGQQQRVCIARCLA 195
Cdd:PRK13638 78 QVATVFQDPEQqiFYTDIDSDIAFSLRNLGVPE----AEITRRVDEALTLVDAQHFR-HQPIQCLSHGQKKRVAIAGALV 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 580041203 196 IEPEVILMDEPTSALDPISTLRVEELVQEL-KEKYTIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFS 267
Cdd:PRK13638 153 LQARYLLLDEPTAGLDPAGRTQMIAIIRRIvAQGNHVIISSHDIDLIYEISDAVYVLRQGQILTHGAPGEVFA 225
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
40-267 |
2.42e-19 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 87.55 E-value: 2.42e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELVPsvkTAGKILYR------------------ 101
Cdd:TIGR03269 4 KNLTKKFDGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMDQYEP---TSGRIIYHvalcekcgyverpskvge 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 102 ------------DQDIFD-QKYSKEQLRTNVGMVFQQPNPF--PKSIYDNITYGPKIHGIKNKKVLDeivekslRGAAIW 166
Cdd:TIGR03269 81 pcpvcggtlepeEVDFWNlSDKLRRRIRKRIAIMLQRTFALygDDTVLDNVLEALEEIGYEGKEAVG-------RAVDLI 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 167 DE--LKDRLHTNAYSLSGGQQQRVCIARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEKYTIIMV--THNMQQAA 242
Cdd:TIGR03269 154 EMvqLSHRITHIARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASGISMVltSHWPEVIE 233
|
250 260
....*....|....*....|....*
gi 580041203 243 RVSDKTAFFLNGYVNEYDDTDKIFS 267
Cdd:TIGR03269 234 DLSDKAIWLENGEIKEEGTPDEVVA 258
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
51-267 |
4.02e-19 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 86.78 E-value: 4.02e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 51 ALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILYR-DQDIFDQKYSKEQLRTNV----GMVFQQ 125
Cdd:TIGR03269 299 AVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLE-----PTSGEVNVRvGDEWVDMTKPGPDGRGRAkryiGILHQE 373
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 126 PNPFP-KSIYDNITYGPKIHGIKNKKVLDEIVEKSLRGaaiWDELKDRLHTNAY--SLSGGQQQRVCIARCLAIEPEVIL 202
Cdd:TIGR03269 374 YDLYPhRTVLDNLTEAIGLELPDELARMKAVITLKMVG---FDEEKAEEILDKYpdELSEGERHRVALAQVLIKEPRIVI 450
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 580041203 203 MDEPTSALDPISTLRVEELVQELKEKY--TIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFS 267
Cdd:TIGR03269 451 LDEPTGTMDPITKVDVTHSILKAREEMeqTFIIVSHDMDFVLDVCDRAALMRDGKIVKIGDPEEIVE 517
|
|
| phnK |
PRK11701 |
phosphonate C-P lyase system protein PhnK; Provisional |
38-269 |
4.63e-19 |
|
phosphonate C-P lyase system protein PhnK; Provisional
Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 84.21 E-value: 4.63e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 38 STQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRmvELVPSvktAGKILYRDQD--IFDQKYSKEQ- 114
Cdd:PRK11701 8 SVRGLTKLYGPRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSA--RLAPD---AGEVHYRMRDgqLRDLYALSEAe 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 115 ----LRTNVGMVFQQPNpfpksiyD----------NItyGPKIHGIKNKKVLDeiveksLRGAAI-WDEL----KDRLHT 175
Cdd:PRK11701 83 rrrlLRTEWGFVHQHPR-------DglrmqvsaggNI--GERLMAVGARHYGD------IRATAGdWLERveidAARIDD 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 176 NAYSLSGGQQQRVCIARCLAIEPEVILMDEPTSALDpIST-------LRveELVQELkeKYTIIMVTHNMQQAARVSDKT 248
Cdd:PRK11701 148 LPTTFSGGMQQRLQIARNLVTHPRLVFMDEPTGGLD-VSVqarlldlLR--GLVREL--GLAVVIVTHDLAVARLLAHRL 222
|
250 260
....*....|....*....|.
gi 580041203 249 AFFLNGYVNEYDDTDKIFSNP 269
Cdd:PRK11701 223 LVMKQGRVVESGLTDQVLDDP 243
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
38-256 |
5.67e-19 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 85.66 E-value: 5.67e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 38 STQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMveLVPsvkTAGKILYRDQDIfdQKYSKEQLRT 117
Cdd:PRK09536 5 DVSDLSVEFGDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGT--LTP---TAGTVLVAGDDV--EALSARAASR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 118 NVGMVFQQPN-PFPKSIYDNITYGPKIH-------GIKNKKVLDEIVEkslRGAAiwDELKDRLHTnaySLSGGQQQRVC 189
Cdd:PRK09536 78 RVASVPQDTSlSFEFDVRQVVEMGRTPHrsrfdtwTETDRAAVERAME---RTGV--AQFADRPVT---SLSGGERQRVL 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 580041203 190 IARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEK-YTIIMVTHNMQQAARVSDKTAFFLNGYV 256
Cdd:PRK09536 150 LARALAQATPVLLLDEPTASLDINHQVRTLELVRRLVDDgKTAVAAIHDLDLAARYCDELVLLADGRV 217
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
52-245 |
7.08e-19 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 83.33 E-value: 7.08e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 52 LQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMvelvpSVKTAGKILYRDQDIfdQKYS---KEQLRTN-VGMVFQQPN 127
Cdd:PRK11629 25 LHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGL-----DTPTSGDVIFNGQPM--SKLSsaaKAELRNQkLGFIYQFHH 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 128 PFPK-SIYDNITYgPKIHGIKNKKvldEIVEKSLRG-AAIwdELKDRLHTNAYSLSGGQQQRVCIARCLAIEPEVILMDE 205
Cdd:PRK11629 98 LLPDfTALENVAM-PLLIGKKKPA---EINSRALEMlAAV--GLEHRANHRPSELSGGERQRVAIARALVNNPRLVLADE 171
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 580041203 206 PTSALDPISTLRVEELVQEL--KEKYTIIMVTHNMQQAARVS 245
Cdd:PRK11629 172 PTGNLDARNADSIFQLLGELnrLQGTAFLVVTHDLQLAKRMS 213
|
|
| dppD |
PRK11022 |
dipeptide transporter ATP-binding subunit; Provisional |
51-275 |
8.45e-19 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 182906 [Multi-domain] Cd Length: 326 Bit Score: 84.41 E-value: 8.45e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 51 ALQNINLDIYENQITAIIGPSGCGKStyIKTLNRMvELV--PSVKTAGKILYRDQDIfdQKYSKEQLRTNVG----MVFQ 124
Cdd:PRK11022 22 AVDRISYSVKQGEVVGIVGESGSGKS--VSSLAIM-GLIdyPGRVMAEKLEFNGQDL--QRISEKERRNLVGaevaMIFQ 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 125 QP----NPFPKSIYdNITYGPKIHGIKNKKVLDEIVEKSLRGAAIWDElKDRLHTNAYSLSGGQQQRVCIARCLAIEPEV 200
Cdd:PRK11022 97 DPmtslNPCYTVGF-QIMEAIKVHQGGNKKTRRQRAIDLLNQVGIPDP-ASRLDVYPHQLSGGMSQRVMIAMAIACRPKL 174
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 580041203 201 ILMDEPTSALDPISTLRVEELVQEL--KEKYTIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNPSNKKTE 275
Cdd:PRK11022 175 LIADEPTTALDVTIQAQIIELLLELqqKENMALVLITHDLALVAEAAHKIIVMYAGQVVETGKAHDIFRAPRHPYTQ 251
|
|
| ABCC_SUR1_N |
cd03290 |
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ... |
45-239 |
2.95e-18 |
|
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213257 [Multi-domain] Cd Length: 218 Bit Score: 81.22 E-value: 2.95e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 45 WYGENHALQNINLDIYENQITAIIGPSGCGKSTYI-KTLNRMVELvpsvktAGKILY--RDQDIFDQKYSKEQLRTNVGM 121
Cdd:cd03290 10 WGSGLATLSNINIRIPTGQLTMIVGQVGCGKSSLLlAILGEMQTL------EGKVHWsnKNESEPSFEATRSRNRYSVAY 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 122 VFQQPNPFPKSIYDNITYGPKIHGIKNKKVLDEI-VEKSLRGAAIWDELKdrLHTNAYSLSGGQQQRVCIARCLAIEPEV 200
Cdd:cd03290 84 AAQKPWLLNATVEENITFGSPFNKQRYKAVTDACsLQPDIDLLPFGDQTE--IGERGINLSGGQRQRICVARALYQNTNI 161
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 580041203 201 ILMDEPTSALD-PISTLRVEELVQEL--KEKYTIIMVTHNMQ 239
Cdd:cd03290 162 VFLDDPFSALDiHLSDHLMQEGILKFlqDDKRTLVLVTHKLQ 203
|
|
| BtuD |
COG4138 |
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ... |
47-247 |
3.08e-18 |
|
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];
Pssm-ID: 443313 [Multi-domain] Cd Length: 248 Bit Score: 81.81 E-value: 3.08e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 47 GENHALQNINLDIYENQITAIIGPSGCGKSTYiktLNRMVELVPSvktAGKILYRDQDIFDqkYSKEQLRTNVGMVFQQ- 125
Cdd:COG4138 7 AVAGRLGPISAQVNAGELIHLIGPNGAGKSTL---LARMAGLLPG---QGEILLNGRPLSD--WSAAELARHRAYLSQQq 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 126 PNPFPKSIYDNIT--YGPKIHGIKNKKVLDEIVEKsLRgaaiwdeLKDRLHTNAYSLSGGQQQRVCIAR-CLAIEPEV-- 200
Cdd:COG4138 79 SPPFAMPVFQYLAlhQPAGASSEAVEQLLAQLAEA-LG-------LEDKLSRPLTQLSGGEWQRVRLAAvLLQVWPTInp 150
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 580041203 201 ----ILMDEPTSALDPISTLRVEELVQELKEK-YTIIMVTHNMQQAARVSDK 247
Cdd:COG4138 151 egqlLLLDEPMNSLDVAQQAALDRLLRELCQQgITVVMSSHDLNHTLRHADR 202
|
|
| SufC |
COG0396 |
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ... |
52-237 |
1.00e-17 |
|
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440165 [Multi-domain] Cd Length: 245 Bit Score: 80.11 E-value: 1.00e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 52 LQNINLDIYENQITAIIGPSGCGKSTYIKTL-NRmvelvPSVK-TAGKILYRDQDIFDqkyskeqLRTN------VGMVF 123
Cdd:COG0396 16 LKGVNLTIKPGEVHAIMGPNGSGKSTLAKVLmGH-----PKYEvTSGSILLDGEDILE-------LSPDeraragIFLAF 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 124 QQPNPFP--------KSIYDNITyGPKIHGIKNKKVLDEIVEK-SLRgaaiwDELKDRlHTNAySLSGGQQQRVCIARCL 194
Cdd:COG0396 84 QYPVEIPgvsvsnflRTALNARR-GEELSAREFLKLLKEKMKElGLD-----EDFLDR-YVNE-GFSGGEKKRNEILQML 155
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 580041203 195 AIEPEVILMDEPTSALDpISTLR-VEELVQELK-EKYTIIMVTHN 237
Cdd:COG0396 156 LLEPKLAILDETDSGLD-IDALRiVAEGVNKLRsPDRGILIITHY 199
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
51-254 |
1.22e-17 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 82.36 E-value: 1.22e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 51 ALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILYRDQDI-FD-QKYSKEQlrtNVGMVFQQPNP 128
Cdd:PRK10762 19 ALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYT-----RDAGSILYLGKEVtFNgPKSSQEA---GIGIIHQELNL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 129 FPK-SIYDNITYG----PKIHGIKNKKVLDEIvekslrgaaiwDELKDRL------HTNAYSLSGGQQQRVCIARCLAIE 197
Cdd:PRK10762 91 IPQlTIAENIFLGrefvNRFGRIDWKKMYAEA-----------DKLLARLnlrfssDKLVGELSIGEQQMVEIAKVLSFE 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 580041203 198 PEVILMDEPTSALDPISTLRVEELVQELK-EKYTIIMVTHNMQQAARVSDKTAFFLNG 254
Cdd:PRK10762 160 SKVIIMDEPTDALTDTETESLFRVIRELKsQGRGIVYISHRLKEIFEICDDVTVFRDG 217
|
|
| nikD |
PRK10418 |
nickel transporter ATP-binding protein NikD; Provisional |
54-274 |
3.23e-17 |
|
nickel transporter ATP-binding protein NikD; Provisional
Pssm-ID: 236688 [Multi-domain] Cd Length: 254 Bit Score: 78.97 E-value: 3.23e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 54 NINLDIYENQITAIIGPSGCGKSTyikTLNRMVELVPS--VKTAGKILyrdqdIFDQKYSKEQLR-TNVGMVFQQP---- 126
Cdd:PRK10418 21 GVSLTLQRGRVLALVGGSGSGKSL---TCAAALGILPAgvRQTAGRVL-----LDGKPVAPCALRgRKIATIMQNPrsaf 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 127 NPFpKSIYDnitygpkiHGIKNKKVL-----DEIVEKSLRGAAIwDELKDRLHTNAYSLSGGQQQRVCIARCLAIEPEVI 201
Cdd:PRK10418 93 NPL-HTMHT--------HARETCLALgkpadDATLTAALEAVGL-ENAARVLKLYPFEMSGGMLQRMMIALALLCEAPFI 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 580041203 202 LMDEPTSALDPISTLRVEELVQELKEKYT--IIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNPSNKKT 274
Cdd:PRK10418 163 IADEPTTDLDVVAQARILDLLESIVQKRAlgMLLVTHDMGVVARLADDVAVMSHGRIVEQGDVETLFNAPKHAVT 237
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
52-243 |
8.45e-17 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 77.51 E-value: 8.45e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 52 LQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILYRDQDI--FDQKySKEQLRT-NVGMVFQQPNP 128
Cdd:PRK10584 26 LTGVELVVKRGETIALIGESGSGKSTLLAILAGLDD-----GSSGEVSLVGQPLhqMDEE-ARAKLRAkHVGFVFQSFML 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 129 FPK-SIYDNITYGPKIHGIKNKKVLDEIVE--KSLrgaaiwdELKDRLHTNAYSLSGGQQQRVCIARCLAIEPEVILMDE 205
Cdd:PRK10584 100 IPTlNALENVELPALLRGESSRQSRNGAKAllEQL-------GLGKRLDHLPAQLSGGEQQRVALARAFNGRPDVLFADE 172
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 580041203 206 PTSALDPISTLRVEELVQELKEKY--TIIMVTHNMQQAAR 243
Cdd:PRK10584 173 PTGNLDRQTGDKIADLLFSLNREHgtTLILVTHDLQLAAR 212
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
51-267 |
1.11e-16 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 79.39 E-value: 1.11e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 51 ALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILYRDQDIfDQKYSKEQLRTNVGMVFQQPNPF- 129
Cdd:PRK10982 13 ALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQ-----KDSGSILFQGKEI-DFKSSKEALENGISMVHQELNLVl 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 130 PKSIYDNI---TYGPKIHGIKNKKVLDEIvekslrgAAIWDEL------KDRLHTnaysLSGGQQQRVCIARCLAIEPEV 200
Cdd:PRK10982 87 QRSVMDNMwlgRYPTKGMFVDQDKMYRDT-------KAIFDELdididpRAKVAT----LSVSQMQMIEIAKAFSYNAKI 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 580041203 201 ILMDEPTSALDPISTLRVEELVQELKEK-YTIIMVTHNMQQAARVSDKTAFFLNG-YVNEYD----DTDKIFS 267
Cdd:PRK10982 156 VIMDEPTSSLTEKEVNHLFTIIRKLKERgCGIVYISHKMEEIFQLCDEITILRDGqWIATQPlaglTMDKIIA 228
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
39-236 |
1.33e-16 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 79.34 E-value: 1.33e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 39 TQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRmvELVPsvkTAGKILYRdqdifdqkyskEQLRtn 118
Cdd:COG0488 1 LENLSKSFGGRPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAG--ELEP---DSGEVSIP-----------KGLR-- 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 119 VGMVFQQPNPFP-KSIYDNITYG-PKIHGIKNKkvLDEIVEKSLRGAAIWDELkDRLHT-----NAY------------- 178
Cdd:COG0488 63 IGYLPQEPPLDDdLTVLDTVLDGdAELRALEAE--LEELEAKLAEPDEDLERL-AELQEefealGGWeaearaeeilsgl 139
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 580041203 179 ------------SLSGGQQQRVCIARCLAIEPEVILMDEPTSALDpISTlrVEELVQELKE-KYTIIMVTH 236
Cdd:COG0488 140 gfpeedldrpvsELSGGWRRRVALARALLSEPDLLLLDEPTNHLD-LES--IEWLEEFLKNyPGTVLVVSH 207
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
51-261 |
2.65e-16 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 78.41 E-value: 2.65e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 51 ALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRmvELVPSvktAGKILYRDQDifdQKYS--KEQLRTNVGMVFQQPNP 128
Cdd:PRK11288 19 ALDDISFDCRAGQVHALMGENGAGKSTLLKILSG--NYQPD---AGSILIDGQE---MRFAstTAALAAGVAIIYQELHL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 129 FPK-SIYDNITYG--PKIHGIKNKKVLDEIVEKSLrgaaiwDELKDRL--HTNAYSLSGGQQQRVCIARCLAIEPEVILM 203
Cdd:PRK11288 91 VPEmTVAENLYLGqlPHKGGIVNRRLLNYEAREQL------EHLGVDIdpDTPLKYLSIGQRQMVEIAKALARNARVIAF 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 204 DEPTSALDPISTLRVEELVQELK-EKYTIIMVTHNMQQAARVSDKTAFFLNG-YVNEYDD 261
Cdd:PRK11288 165 DEPTSSLSAREIEQLFRVIRELRaEGRVILYVSHRMEEIFALCDAITVFKDGrYVATFDD 224
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
21-247 |
3.15e-16 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 77.56 E-value: 3.15e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 21 QSHHKTPDDTNSHSVIYSTQNLDLW-----YGENHALQNINLDIYENQITAIIGPSGCGKSTyiktLNRMVeLVPSVKTA 95
Cdd:PRK13536 21 RKHQGISEAKASIPGSMSTVAIDLAgvsksYGDKAVVNGLSFTVASGECFGLLGPNGAGKST----IARMI-LGMTSPDA 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 96 GKILYRDQDIFDQKYSKeqlRTNVGMVFQQPNPFPK-SIYDNITYGPKIHGIKNKKVldEIVEKSLRGAAiwdELKDRLH 174
Cdd:PRK13536 96 GKITVLGVPVPARARLA---RARIGVVPQFDNLDLEfTVRENLLVFGRYFGMSTREI--EAVIPSLLEFA---RLESKAD 167
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 580041203 175 TNAYSLSGGQQQRVCIARCLAIEPEVILMDEPTSALDPIST-LRVEELVQELKEKYTIIMVTHNMQQAARVSDK 247
Cdd:PRK13536 168 ARVSDLSGGMKRRLTLARALINDPQLLILDEPTTGLDPHARhLIWERLRSLLARGKTILLTTHFMEEAERLCDR 241
|
|
| PRK10790 |
PRK10790 |
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein; |
40-236 |
3.61e-16 |
|
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 78.22 E-value: 3.61e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGENH-ALQNINLDIYENQITAIIGPSGCGKSTYIKTLnrMVELVPsvkTAGKILYRDQDIfdQKYSKEQLRTN 118
Cdd:PRK10790 344 DNVSFAYRDDNlVLQNINLSVPSRGFVALVGHTGSGKSTLASLL--MGYYPL---TEGEIRLDGRPL--SSLSHSVLRQG 416
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 119 VGMVFQQPNPFPKSIYDNITYGPKIHGIKNKKVLdEIVEKSLRGAAIWDELKDRLHTNAYSLSGGQQQRVCIARCLAIEP 198
Cdd:PRK10790 417 VAMVQQDPVVLADTFLANVTLGRDISEEQVWQAL-ETVQLAELARSLPDGLYTPLGEQGNNLSVGQKQLLALARVLVQTP 495
|
170 180 190
....*....|....*....|....*....|....*...
gi 580041203 199 EVILMDEPTSALDPISTLRVEELVQELKEKYTIIMVTH 236
Cdd:PRK10790 496 QILILDEATANIDSGTEQAIQQALAAVREHTTLVVIAH 533
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
40-254 |
9.66e-16 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 72.48 E-value: 9.66e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTL-NRMVELVPSVKTAG--KILYrdqdiFDQkyskeqlr 116
Cdd:cd03221 4 ENLSKTYGGKLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIaGELEPDEGIVTWGStvKIGY-----FEQ-------- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 117 tnvgmvfqqpnpfpksiydnitygpkihgiknkkvldeivekslrgaaiwdelkdrlhtnaysLSGGQQQRVCIARCLAI 196
Cdd:cd03221 71 ---------------------------------------------------------------LSGGEKMRLALAKLLLE 87
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 580041203 197 EPEVILMDEPTSALDPIStlrVEELVQELKEKY-TIIMVTHNMQQAARVSDKTAFFLNG 254
Cdd:cd03221 88 NPNLLLLDEPTNHLDLES---IEALEEALKEYPgTVILVSHDRYFLDQVATKIIELEDG 143
|
|
| ABCD_peroxisomal_ALDP |
cd03223 |
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ... |
52-236 |
9.71e-16 |
|
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).
Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 72.96 E-value: 9.71e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 52 LQNINLDIYENQITAIIGPSGCGKSTYIKTLNrmvELVPSVKtaGKI-LYRDQDIFdqkyskeqlrtnvgMVFQQPnpfp 130
Cdd:cd03223 17 LKDLSFEIKPGDRLLITGPSGTGKSSLFRALA---GLWPWGS--GRIgMPEGEDLL--------------FLPQRP---- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 131 ksiydnitYGPkihgiknkkvldeivEKSLRGAAI--WDELkdrlhtnaysLSGGQQQRVCIARCLAIEPEVILMDEPTS 208
Cdd:cd03223 74 --------YLP---------------LGTLREQLIypWDDV----------LSGGEQQRLAFARLLLHKPKFVFLDEATS 120
|
170 180
....*....|....*....|....*...
gi 580041203 209 ALDPISTLRVEELVQElkEKYTIIMVTH 236
Cdd:cd03223 121 ALDEESEDRLYQLLKE--LGITVISVGH 146
|
|
| YddA |
COG4178 |
ABC-type uncharacterized transport system, permease and ATPase components [General function ... |
52-236 |
1.33e-15 |
|
ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];
Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 76.38 E-value: 1.33e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 52 LQNINLDIYENQITAIIGPSGCGKSTYIKTLNrmvELVPSvkTAGKILYRDQDifdqkyskeqlrtnvGMVF--QQPnpf 129
Cdd:COG4178 379 LEDLSLSLKPGERLLITGPSGSGKSTLLRAIA---GLWPY--GSGRIARPAGA---------------RVLFlpQRP--- 435
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 130 pksiY-------DNITYgPKIHGiknkKVLDEIVEKSLRGAAIwDELKDRLHTNA---YSLSGGQQQRVCIARCLAIEPE 199
Cdd:COG4178 436 ----YlplgtlrEALLY-PATAE----AFSDAELREALEAVGL-GHLAERLDEEAdwdQVLSLGEQQRLAFARLLLHKPD 505
|
170 180 190
....*....|....*....|....*....|....*..
gi 580041203 200 VILMDEPTSALDPISTLRVEELVQELKEKYTIIMVTH 236
Cdd:COG4178 506 WLFLDEATSALDEENEAALYQLLREELPGTTVISVGH 542
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
36-254 |
1.85e-15 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 74.84 E-value: 1.85e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 36 IYSTQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLnrmveLVPSVKTAGKILYRDQDIFDQKyskEQL 115
Cdd:PRK13537 7 PIDFRNVEKRYGDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRML-----LGLTHPDAGSISLCGEPVPSRA---RHA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 116 RTNVGMVFQQPNPFPK-SIYDNITYGPKIHGIKNKKVlDEIVEKSLRGAaiwdELKDRLHTNAYSLSGGQQQRVCIARCL 194
Cdd:PRK13537 79 RQRVGVVPQFDNLDPDfTVRENLLVFGRYFGLSAAAA-RALVPPLLEFA----KLENKADAKVGELSGGMKRRLTLARAL 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 580041203 195 AIEPEVILMDEPTSALDPIST-LRVEELVQELKEKYTIIMVTHNMQQAARVSDKTAFFLNG 254
Cdd:PRK13537 154 VNDPDVLVLDEPTTGLDPQARhLMWERLRSLLARGKTILLTTHFMEEAERLCDRLCVIEEG 214
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
46-247 |
2.02e-15 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 75.98 E-value: 2.02e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 46 YGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILYRDQDiFDQKYSKEQLRTNVGMVFQQ 125
Cdd:PRK09700 15 FGPVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHE-----PTKGTITINNIN-YNKLDHKLAAQLGIGIIYQE 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 126 PNPFPK-SIYDNITYG----PKIHGIknkKVLDeIVEKSLRGAAIWDE--LKDRLHTNAYSLSGGQQQRVCIARCLAIEP 198
Cdd:PRK09700 89 LSVIDElTVLENLYIGrhltKKVCGV---NIID-WREMRVRAAMMLLRvgLKVDLDEKVANLSISHKQMLEIAKTLMLDA 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 580041203 199 EVILMDEPTSALDPISTLRVEELVQEL-KEKYTIIMVTHNMQQAARVSDK 247
Cdd:PRK09700 165 KVIIMDEPTSSLTNKEVDYLFLIMNQLrKEGTAIVYISHKLAEIRRICDR 214
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
53-238 |
4.02e-15 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 75.45 E-value: 4.02e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 53 QNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILYRDQDIFdQKYSKEQLRTNVGMVFQQPNPFPKS 132
Cdd:PTZ00265 402 KDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYD-----PTEGDIIINDSHNL-KDINLKWWRSKIGVVSQDPLLFSNS 475
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 133 IYDNITYG-------------------------------------------------PKIHGIKNKKVLD--EIVEKSLR 161
Cdd:PTZ00265 476 IKNNIKYSlyslkdlealsnyynedgndsqenknkrnscrakcagdlndmsnttdsnELIEMRKNYQTIKdsEVVDVSKK 555
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 162 G------AAIWDELKDRLHTNAYSLSGGQQQRVCIARCLAIEPEVILMDEPTSALDPISTLRVEELVQELK--EKYTIIM 233
Cdd:PTZ00265 556 VlihdfvSALPDKYETLVGSNASKLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQKTINNLKgnENRITII 635
|
....*
gi 580041203 234 VTHNM 238
Cdd:PTZ00265 636 IAHRL 640
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
47-237 |
6.15e-15 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 71.83 E-value: 6.15e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 47 GENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLnrmVELVPsvKTAGKILYRDQDIFDQKYS------------KEQ 114
Cdd:PRK13539 13 GGRVLFSGLSFTLAAGEALVLTGPNGSGKTTLLRLI---AGLLP--PAAGTIKLDGGDIDDPDVAeachylghrnamKPA 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 115 LrtnvgmvfqqpnpfpkSIYDNITYGPKIHGIKNKKVLDEIvekslrgAAIwdELKDRLHTNAYSLSGGQQQRVCIARCL 194
Cdd:PRK13539 88 L----------------TVAENLEFWAAFLGGEELDIAAAL-------EAV--GLAPLAHLPFGYLSAGQKRRVALARLL 142
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 580041203 195 AIEPEVILMDEPTSALDPISTLRVEELVQE-LKEKYTIIMVTHN 237
Cdd:PRK13539 143 VSNRPIWILDEPTAALDAAAVALFAELIRAhLAQGGIVIAATHI 186
|
|
| type_I_sec_PrtD |
TIGR01842 |
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ... |
47-236 |
9.31e-15 |
|
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 200134 [Multi-domain] Cd Length: 544 Bit Score: 73.92 E-value: 9.31e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 47 GENHALQNINLDIYENQITAIIGPSGCGKSTYIKTlnrMVELVPSvkTAGKILYRDQDIfdQKYSKEQLRTNVGMVFQQP 126
Cdd:TIGR01842 329 GKKPTLRGISFSLQAGEALAIIGPSGSGKSTLARL---IVGIWPP--TSGSVRLDGADL--KQWDRETFGKHIGYLPQDV 401
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 127 NPFPKSIYDNIT-YGPKIHGiknkkvlDEIVEKS-LRGAaiwDELKDRLhTNAY---------SLSGGQQQRVCIARCLA 195
Cdd:TIGR01842 402 ELFPGTVAENIArFGENADP-------EKIIEAAkLAGV---HELILRL-PDGYdtvigpggaTLSGGQRQRIALARALY 470
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 580041203 196 IEPEVILMDEPTSALDPISTLRVEELVQELK-EKYTIIMVTH 236
Cdd:TIGR01842 471 GDPKLVVLDEPNSNLDEEGEQALANAIKALKaRGITVVVITH 512
|
|
| PRK10789 |
PRK10789 |
SmdA family multidrug ABC transporter permease/ATP-binding protein; |
48-236 |
1.28e-14 |
|
SmdA family multidrug ABC transporter permease/ATP-binding protein;
Pssm-ID: 182732 [Multi-domain] Cd Length: 569 Bit Score: 73.59 E-value: 1.28e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 48 ENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELvpsvkTAGKILYRDQDIFDQKYskEQLRTNVGMVFQQPN 127
Cdd:PRK10789 327 DHPALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDV-----SEGDIRFHDIPLTKLQL--DSWRSRLAVVSQTPF 399
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 128 PFPKSIYDNITYGpkihgikNKKVLDEIVEKSLRGAAIWDELKdRLhTNAYS---------LSGGQQQRVCIARCLAIEP 198
Cdd:PRK10789 400 LFSDTVANNIALG-------RPDATQQEIEHVARLASVHDDIL-RL-PQGYDtevgergvmLSGGQKQRISIARALLLNA 470
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 580041203 199 EVILMDEPTSALDPistlRVE-ELVQELK---EKYTIIMVTH 236
Cdd:PRK10789 471 EILILDDALSAVDG----RTEhQILHNLRqwgEGRTVIISAH 508
|
|
| PRK15056 |
PRK15056 |
manganese/iron ABC transporter ATP-binding protein; |
32-248 |
2.68e-14 |
|
manganese/iron ABC transporter ATP-binding protein;
Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 71.07 E-value: 2.68e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 32 SHSVIYSTQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELvpsvkTAGKILYRDQDIfdqkys 111
Cdd:PRK15056 3 QQAGIVVNDVTVTWRNGHTALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRL-----ASGKISILGQPT------ 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 112 KEQLRTN-VGMVFQQPN---PFPKSIYDNITYGPKIHG--IKNKKVLD-EIVEKSLrgaAIWDELKDRlHTNAYSLSGGQ 184
Cdd:PRK15056 72 RQALQKNlVAYVPQSEEvdwSFPVLVEDVVMMGRYGHMgwLRRAKKRDrQIVTAAL---ARVDMVEFR-HRQIGELSGGQ 147
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 580041203 185 QQRVCIARCLAIEPEVILMDEPTSALDPISTLRVEELVQELK-EKYTIIMVTHNMQQAARVSDKT 248
Cdd:PRK15056 148 KKRVFLARAIAQQGQVILLDEPFTGVDVKTEARIISLLRELRdEGKTMLVSTHNLGSVTEFCDYT 212
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
28-246 |
1.31e-13 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 69.05 E-value: 1.31e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 28 DDTNSHSVIYSTQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMvelvpSVKTAGKILYRDQDI-- 105
Cdd:PRK10575 3 EYTNHSDTTFALRNVSFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRH-----QPPSEGEILLDAQPLes 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 106 -----FDQK--YSKEQLRTNVGMVFQQPNPFPKSIYdnitygpkiHG------IKNKKVLDEIVekSLRGaaiwdeLKDR 172
Cdd:PRK10575 78 wsskaFARKvaYLPQQLPAAEGMTVRELVAIGRYPW---------HGalgrfgAADREKVEEAI--SLVG------LKPL 140
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 580041203 173 LHTNAYSLSGGQQQRVCIARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEK--YTIIMVTHNMQQAARVSD 246
Cdd:PRK10575 141 AHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQErgLTVIAVLHDINMAARYCD 216
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
61-234 |
3.66e-13 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 69.04 E-value: 3.66e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 61 ENQITAIIGPSGCGKSTYIKTLNRmvELVPSV--------------KTAGKILyrdQDIFdQKYSKEQLRTNVgmvfqqp 126
Cdd:COG1245 98 KGKVTGILGPNGIGKSTALKILSG--ELKPNLgdydeepswdevlkRFRGTEL---QDYF-KKLANGEIKVAH------- 164
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 127 npfpKSIY-DNItygPKIHGIKNKKVLDEIVEkslRGAaiWDELKDRLHTNAY------SLSGGQQQRVCIARCLAIEPE 199
Cdd:COG1245 165 ----KPQYvDLI---PKVFKGTVRELLEKVDE---RGK--LDELAEKLGLENIldrdisELSGGELQRVAIAAALLRDAD 232
|
170 180 190
....*....|....*....|....*....|....*
gi 580041203 200 VILMDEPTSALDPISTLRVEELVQELKEKYTIIMV 234
Cdd:COG1245 233 FYFFDEPSSYLDIYQRLNVARLIRELAEEGKYVLV 267
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
61-238 |
4.45e-13 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 69.07 E-value: 4.45e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 61 ENQITAIIGPSGCGKSTYIKTLNRmvELVPSV--------------KTAGKILyrdQDIFDQKYSKEqLRTNVgmvfqqp 126
Cdd:PRK13409 98 EGKVTGILGPNGIGKTTAVKILSG--ELIPNLgdyeeepswdevlkRFRGTEL---QNYFKKLYNGE-IKVVH------- 164
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 127 npfpKSIYdnITYGPKIHGIKNKKVLDEIVEkslRGaaIWDELKDRLHTNAY------SLSGGQQQRVCIARCLAIEPEV 200
Cdd:PRK13409 165 ----KPQY--VDLIPKVFKGKVRELLKKVDE---RG--KLDEVVERLGLENIldrdisELSGGELQRVAIAAALLRDADF 233
|
170 180 190
....*....|....*....|....*....|....*...
gi 580041203 201 ILMDEPTSALDPISTLRVEELVQELKEKYTIIMVTHNM 238
Cdd:PRK13409 234 YFFDEPTSYLDIRQRLNVARLIRELAEGKYVLVVEHDL 271
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
132-246 |
4.67e-13 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 68.89 E-value: 4.67e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 132 SIYDNITYgPKIHGIKNKKVLDEiveKSLRGAAiwDELKDRL-------HTNAYSLSGGQQQRVCIARCLAIEPEVILMD 204
Cdd:COG1129 346 SIRENITL-ASLDRLSRGGLLDR---RRERALA--EEYIKRLriktpspEQPVGNLSGGNQQKVVLAKWLATDPKVLILD 419
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 580041203 205 EPTSALDpISTlRVE--ELVQEL-KEKYTIIMVTHNMQQAARVSD 246
Cdd:COG1129 420 EPTRGID-VGA-KAEiyRLIRELaAEGKAVIVISSELPELLGLSD 462
|
|
| SapD |
COG4170 |
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms]; |
47-269 |
5.00e-13 |
|
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
Pssm-ID: 443330 [Multi-domain] Cd Length: 331 Bit Score: 68.01 E-value: 5.00e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 47 GENHALQNINLDIYENQITAIIGPSGCGKSTYIKTL------NRMVelvpsvkTAGKILYRDQDIFdqKYSKEQLR---- 116
Cdd:COG4170 18 GRVKAVDRVSLTLNEGEIRGLVGESGSGKSLIAKAIcgitkdNWHV-------TADRFRWNGIDLL--KLSPRERRkiig 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 117 TNVGMVFQQPNpfpkSIYDnitygPkihgikNKKVLDEIVE----KSLRGAaIWDELKDR-------LH----------T 175
Cdd:COG4170 89 REIAMIFQEPS----SCLD-----P------SAKIGDQLIEaipsWTFKGK-WWQRFKWRkkraielLHrvgikdhkdiM 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 176 NAYS--LSGGQQQRVCIARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKE--KYTIIMVTHNMQQAARVSDKTAFF 251
Cdd:COG4170 153 NSYPheLTEGECQKVMIAMAIANQPRLLIADEPTNAMESTTQAQIFRLLARLNQlqGTSILLISHDLESISQWADTITVL 232
|
250
....*....|....*...
gi 580041203 252 LNGYVNEYDDTDKIFSNP 269
Cdd:COG4170 233 YCGQTVESGPTEQILKSP 250
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
48-236 |
8.08e-13 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 66.14 E-value: 8.08e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 48 ENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLnrmVELVPSVKTAGKIlyrdqDIFDQKYSKEqlrtnvgmvfqqpn 127
Cdd:COG2401 42 ERYVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLL---AGALKGTPVAGCV-----DVPDNQFGRE-------------- 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 128 pfpKSIYDNItygPKIHGIKNKKVLDEIVekSLRGAAIW----DELkdrlhtnayslSGGQQQRVCIARCLAIEPEVILM 203
Cdd:COG2401 100 ---ASLIDAI---GRKGDFKDAVELLNAV--GLSDAVLWlrrfKEL-----------STGQKFRFRLALLLAERPKLLVI 160
|
170 180 190
....*....|....*....|....*....|....*
gi 580041203 204 DEPTSALDPISTLRVEELVQEL--KEKYTIIMVTH 236
Cdd:COG2401 161 DEFCSHLDRQTAKRVARNLQKLarRAGITLVVATH 195
|
|
| ABC_RNaseL_inhibitor_domain1 |
cd03236 |
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
61-238 |
1.38e-12 |
|
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 65.85 E-value: 1.38e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 61 ENQITAIIGPSGCGKSTYIKTLNRmvELVPSVKTAGK------IL--YRDQDIfdQKYSKEQLRTNVGMVF--QQPNPFP 130
Cdd:cd03236 25 EGQVLGLVGPNGIGKSTALKILAG--KLKPNLGKFDDppdwdeILdeFRGSEL--QNYFTKLLEGDVKVIVkpQYVDLIP 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 131 KSIYDNItyGPKIHGIKNKKVLDEIVEKSlrgaaiwdELKDRLHTNAYSLSGGQQQRVCIARCLAIEPEVILMDEPTSAL 210
Cdd:cd03236 101 KAVKGKV--GELLKKKDERGKLDELVDQL--------ELRHVLDRNIDQLSGGELQRVAIAAALARDADFYFFDEPSSYL 170
|
170 180
....*....|....*....|....*....
gi 580041203 211 DPISTLRVEELVQEL-KEKYTIIMVTHNM 238
Cdd:cd03236 171 DIKQRLNAARLIRELaEDDNYVLVVEHDL 199
|
|
| ABC_RNaseL_inhibitor_domain2 |
cd03237 |
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
58-251 |
1.47e-12 |
|
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 65.89 E-value: 1.47e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 58 DIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKIlyrDQDIFDQKYSKEQLRTNVGMVFQQpnpFPKSIYDNI 137
Cdd:cd03237 21 SISESEVIGILGPNGIGKTTFIKMLAGVLK-----PDEGDI---EIELDTVSYKPQYIKADYEGTVRD---LLSSITKDF 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 138 TYGPK-IHGIKNKKVLDEIVEKSLRgaaiwdelkdrlhtnaySLSGGQQQRVCIARCLAIEPEVILMDEPTSALDPISTL 216
Cdd:cd03237 90 YTHPYfKTEIAKPLQIEQILDREVP-----------------ELSGGELQRVAIAACLSKDADIYLLDEPSAYLDVEQRL 152
|
170 180 190
....*....|....*....|....*....|....*..
gi 580041203 217 RVEELVQE--LKEKYTIIMVTHNMQQAARVSDKTAFF 251
Cdd:cd03237 153 MASKVIRRfaENNEKTAFVVEHDIIMIDYLADRLIVF 189
|
|
| PRK15093 |
PRK15093 |
peptide ABC transporter ATP-binding protein SapD; |
51-278 |
2.56e-12 |
|
peptide ABC transporter ATP-binding protein SapD;
Pssm-ID: 185049 [Multi-domain] Cd Length: 330 Bit Score: 65.98 E-value: 2.56e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 51 ALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELVPSVkTAGKILYRDQDIFdqKYSKEQLRT----NVGMVFQQP 126
Cdd:PRK15093 22 AVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGVTKDNWRV-TADRMRFDDIDLL--RLSPRERRKlvghNVSMIFQEP 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 127 ----NP---FPKSIYDNI---TY-GP---KIHGIKNKKVldeiveKSLRGAAIWDElKDRLHTNAYSLSGGQQQRVCIAR 192
Cdd:PRK15093 99 qsclDPserVGRQLMQNIpgwTYkGRwwqRFGWRKRRAI------ELLHRVGIKDH-KDAMRSFPYELTEGECQKVMIAI 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 193 CLAIEPEVILMDEPTSALDPISTLRVEELVQELKEK--YTIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSNPS 270
Cdd:PRK15093 172 ALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLNQNnnTTILLISHDLQMLSQWADKINVLYCGQTVETAPSKELVTTPH 251
|
....*...
gi 580041203 271 NKKTEDYI 278
Cdd:PRK15093 252 HPYTQALI 259
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
44-246 |
2.62e-12 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 66.51 E-value: 2.62e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 44 LWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELvpsvkTAGKILYrDQDIfdqKYSKEQlrtnvgmvf 123
Cdd:PRK11147 11 LSFSDAPLLDNAELHIEDNERVCLVGRNGAGKSTLMKILNGEVLL-----DDGRIIY-EQDL---IVARLQ--------- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 124 QQPnpfPK----SIYDNITYGPKIHGIKNK-------KVLDEIVEKSLRGAAiwdELKDRL-HTNAY------------- 178
Cdd:PRK11147 73 QDP---PRnvegTVYDFVAEGIEEQAEYLKryhdishLVETDPSEKNLNELA---KLQEQLdHHNLWqlenrinevlaql 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 179 ---------SLSGGQQQRVCIARCLAIEPEVILMDEPTSALDpISTlrVEELVQELKE-KYTIIMVTH------NMqqAA 242
Cdd:PRK11147 147 gldpdaalsSLSGGWLRKAALGRALVSNPDVLLLDEPTNHLD-IET--IEWLEGFLKTfQGSIIFISHdrsfirNM--AT 221
|
....
gi 580041203 243 RVSD 246
Cdd:PRK11147 222 RIVD 225
|
|
| ycf16 |
CHL00131 |
sulfate ABC transporter protein; Validated |
30-236 |
1.18e-11 |
|
sulfate ABC transporter protein; Validated
Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 63.12 E-value: 1.18e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 30 TNSHSVIYSTQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMvelvPSVK-TAGKILYRDQDIFDq 108
Cdd:CHL00131 1 MNKNKPILEIKNLHASVNENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAGH----PAYKiLEGDILFKGESILD- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 109 KYSKEQLRTNVGMVFQQPNPFP---KSIYDNITYGPKiHGIKNKKVLD-----EIVEKSLRgaaIWDELKDRLHTNAYS- 179
Cdd:CHL00131 76 LEPEERAHLGIFLAFQYPIEIPgvsNADFLRLAYNSK-RKFQGLPELDpleflEIINEKLK---LVGMDPSFLSRNVNEg 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 580041203 180 LSGGQQQRVCIARCLAIEPEVILMDEPTSALDpISTLR-VEELVQELKEKYT-IIMVTH 236
Cdd:CHL00131 152 FSGGEKKRNEILQMALLDSELAILDETDSGLD-IDALKiIAEGINKLMTSENsIILITH 209
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
52-265 |
1.21e-11 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 64.69 E-value: 1.21e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 52 LQNINLDIYENQITAIIGPSGCGKSTYIKTlnrMVELVPSvkTAGKILYRDQDIFDQKYSKEQlRTNVGMVFQQPNPFPK 131
Cdd:PRK15439 27 LKGIDFTLHAGEVHALLGGNGAGKSTLMKI---IAGIVPP--DSGTLEIGGNPCARLTPAKAH-QLGIYLVPQEPLLFPN 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 132 -SIYDNITYG-PKIHGIKNKkvldeiVEKSLrgAAIWDELKdrLHTNAYSLSGGQQQRVCIARCLAIEPEVILMDEPTSA 209
Cdd:PRK15439 101 lSVKENILFGlPKRQASMQK------MKQLL--AALGCQLD--LDSSAGSLEVADRQIVEILRGLMRDSRILILDEPTAS 170
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 580041203 210 LDPISTLRVEELVQELKEK-YTIIMVTHNMQQAARVSDKTAFFLNGYV------NEYDDTDKI 265
Cdd:PRK15439 171 LTPAETERLFSRIRELLAQgVGIVFISHKLPEIRQLADRISVMRDGTIalsgktADLSTDDII 233
|
|
| ccmA |
TIGR01189 |
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ... |
38-236 |
1.34e-11 |
|
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]
Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 62.38 E-value: 1.34e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 38 STQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLnrmVELVPSvkTAGKILYRDQDIFDQKyskEQLRT 117
Cdd:TIGR01189 2 AARNLACSRGERMLFEGLSFTLNAGEALQVTGPNGIGKTTLLRIL---AGLLRP--DSGEVRWNGTPLAEQR---DEPHE 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 118 NVGMVFQQPNPFPK-SIYDNITYGPKIHGIKNKKVLDEIVEKSLRGAAiwdelkdrlHTNAYSLSGGQQQRVCIARCLAI 196
Cdd:TIGR01189 74 NILYLGHLPGLKPElSALENLHFWAAIHGGAQRTIEDALAAVGLTGFE---------DLPAAQLSAGQQRRLALARLWLS 144
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 580041203 197 EPEVILMDEPTSALDPISTLRVEELVQE-LKEKYTIIMVTH 236
Cdd:TIGR01189 145 RRPLWILDEPTTALDKAGVALLAGLLRAhLARGGIVLLTTH 185
|
|
| ABC_Carb_Monos_II |
cd03215 |
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
51-246 |
1.36e-11 |
|
Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 61.68 E-value: 1.36e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 51 ALQNINLDIYENQITAIIGPSGCGKStyiktlnrmvELVPSV-----KTAGKILYRDQDIfDQKYSKEQLRTNVGMVfqq 125
Cdd:cd03215 15 AVRDVSFEVRAGEIVGIAGLVGNGQT----------ELAEALfglrpPASGEITLDGKPV-TRRSPRDAIRAGIAYV--- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 126 pnpfPKSiydnitygPKIHGIknkkVLDEIVEKSLrgaaiwdelkdrlhTNAYSLSGGQQQRVCIARCLAIEPEVILMDE 205
Cdd:cd03215 81 ----PED--------RKREGL----VLDLSVAENI--------------ALSSLLSGGNQQKVVLARWLARDPRVLILDE 130
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 580041203 206 PTSALDPISTLRVEELVQELKEK-YTIIMVTHNMQQAARVSD 246
Cdd:cd03215 131 PTRGVDVGAKAEIYRLIRELADAgKAVLLISSELDELLGLCD 172
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
46-254 |
1.40e-11 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 64.46 E-value: 1.40e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 46 YGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNrmvELVPSVKTAGKILYRDQDIFDQKYSKEQlRTNVGMVFQQ 125
Cdd:TIGR02633 11 FGGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILS---GVYPHGTWDGEIYWSGSPLKASNIRDTE-RAGIVIIHQE 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 126 PNPFPK-SIYDNITYGpkiHGIKNKKVLDEIVEKSLRGAAIWDELKDRLHTNAYSLS---GGQQQRVCIARCLAIEPEVI 201
Cdd:TIGR02633 87 LTLVPElSVAENIFLG---NEITLPGGRMAYNAMYLRAKNLLRELQLDADNVTRPVGdygGGQQQLVEIAKALNKQARLL 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 580041203 202 LMDEPTSALDPISTLRVEELVQELKEK-YTIIMVTHNMQQAARVSDKTAFFLNG 254
Cdd:TIGR02633 164 ILDEPSSSLTEKETEILLDIIRDLKAHgVACVYISHKLNEVKAVCDTICVIRDG 217
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
59-250 |
1.48e-11 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 64.44 E-value: 1.48e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 59 IYENQITAIIGPSGCGKSTYIKTLNRmvELVP---SVKTAGKILYRDQDIfdqkyskeqlRTNVGMVFQQpnpFPKSIYD 135
Cdd:PRK13409 362 IYEGEVIGIVGPNGIGKTTFAKLLAG--VLKPdegEVDPELKISYKPQYI----------KPDYDGTVED---LLRSITD 426
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 136 NITYGPKIHGIKNKKVLDEIVEKSLRGaaiwdelkdrlhtnaysLSGGQQQRVCIARCLAIEPEVILMDEPTSALDpist 215
Cdd:PRK13409 427 DLGSSYYKSEIIKPLQLERLLDKNVKD-----------------LSGGELQRVAIAACLSRDADLYLLDEPSAHLD---- 485
|
170 180 190
....*....|....*....|....*....|....*
gi 580041203 216 lrVEELvqelkekytiIMVTHNMQQAARVSDKTAF 250
Cdd:PRK13409 486 --VEQR----------LAVAKAIRRIAEEREATAL 508
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
63-236 |
1.59e-11 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 62.13 E-value: 1.59e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 63 QITAIIGPSGCGKSTYIKTLNRMvelvpSVKTAGKILYRDQDIFDQKYSKEQlrtnvGMVFQQPNPFPK---SIYDNITY 139
Cdd:cd03231 27 EALQVTGPNGSGKTTLLRILAGL-----SPPLAGRVLLNGGPLDFQRDSIAR-----GLLYLGHAPGIKttlSVLENLRF 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 140 GPKIHGikNKKVLDEIVEKSLRGAAiwdelkdrlHTNAYSLSGGQQQRVCIARCLAIEPEVILMDEPTSALDPISTLRVE 219
Cdd:cd03231 97 WHADHS--DEQVEEALARVGLNGFE---------DRPVAQLSAGQQRRVALARLLLSGRPLWILDEPTTALDKAGVARFA 165
|
170
....*....|....*...
gi 580041203 220 ELV-QELKEKYTIIMVTH 236
Cdd:cd03231 166 EAMaGHCARGGMVVLTTH 183
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
58-247 |
1.63e-11 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 64.42 E-value: 1.63e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 58 DIYENQITAIIGPSGCGKSTYIKTLNRmvELVP---SVKTAGKILYRDQDI-FDQKYSKEQ-LRTNVGmvfqqpNPFPKS 132
Cdd:COG1245 362 EIREGEVLGIVGPNGIGKTTFAKILAG--VLKPdegEVDEDLKISYKPQYIsPDYDGTVEEfLRSANT------DDFGSS 433
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 133 IYDnitygpkiHGIKNKKVLDEIVEKSLRgaaiwdelkdrlhtnaySLSGGQQQRVCIARCLAIEPEVILMDEPTSALDp 212
Cdd:COG1245 434 YYK--------TEIIKPLGLEKLLDKNVK-----------------DLSGGELQRVAIAACLSRDADLYLLDEPSAHLD- 487
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 580041203 213 istlrVEELVQ---------ELKEKyTIIMVTHNMQQAARVSDK 247
Cdd:COG1245 488 -----VEQRLAvakairrfaENRGK-TAMVVDHDIYLIDYISDR 525
|
|
| PRK03695 |
PRK03695 |
vitamin B12-transporter ATPase; Provisional |
64-244 |
1.96e-11 |
|
vitamin B12-transporter ATPase; Provisional
Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 62.64 E-value: 1.96e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 64 ITAIIGPSGCGKSTYiktLNRMVELVPSvktAGKILYRDQDIFDqkYS-KEQLRTNVGMVFQQPNPFPKSIYDNIT-YGP 141
Cdd:PRK03695 24 ILHLVGPNGAGKSTL---LARMAGLLPG---SGSIQFAGQPLEA--WSaAELARHRAYLSQQQTPPFAMPVFQYLTlHQP 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 142 -KIHGIKNKKVLDEIVEkSLRgaaiwdeLKDRLHTNAYSLSGGQQQRVCIAR-CLAIEPEV------ILMDEPTSALDPI 213
Cdd:PRK03695 96 dKTRTEAVASALNEVAE-ALG-------LDDKLGRSVNQLSGGEWQRVRLAAvVLQVWPDInpagqlLLLDEPMNSLDVA 167
|
170 180 190
....*....|....*....|....*....|....*.
gi 580041203 214 STLRVEELVQELKEK-YTIIMVTHNM----QQAARV 244
Cdd:PRK03695 168 QQAALDRLLSELCQQgIAVVMSSHDLnhtlRHADRV 203
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
36-236 |
2.03e-11 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 63.80 E-value: 2.03e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 36 IYSTQNLDLWYGEN-HALQNINLDIYENQITAIIGPSGCGKSTYIKTLnrmvelvpsvktAGkilyrdqdiFDQKYSKE- 113
Cdd:TIGR03719 4 IYTMNRVSKVVPPKkEILKDISLSFFPGAKIGVLGLNGAGKSTLLRIM------------AG---------VDKDFNGEa 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 114 --QLRTNVGMVFQQPNPFP-KSIYDNITYGpkIHGIKNK-KVLDEIVEKSLRGAAIWD-------ELKDRL-HTNAYS-- 179
Cdd:TIGR03719 63 rpQPGIKVGYLPQEPQLDPtKTVRENVEEG--VAEIKDAlDRFNEISAKYAEPDADFDklaaeqaELQEIIdAADAWDld 140
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 580041203 180 ---------------------LSGGQQQRVCIARCLAIEPEVILMDEPTSALDPIStlrVEELVQELKE-KYTIIMVTH 236
Cdd:TIGR03719 141 sqleiamdalrcppwdadvtkLSGGERRRVALCRLLLSKPDMLLLDEPTNHLDAES---VAWLERHLQEyPGTVVAVTH 216
|
|
| hmuV |
PRK13547 |
heme ABC transporter ATP-binding protein; |
40-256 |
2.44e-11 |
|
heme ABC transporter ATP-binding protein;
Pssm-ID: 184132 [Multi-domain] Cd Length: 272 Bit Score: 62.54 E-value: 2.44e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRmvELVPSVKTAGKILYRDQDIFDQKYSK---EQLR 116
Cdd:PRK13547 5 DHLHVARRHRAILRDLSLRIEPGRVTALLGRNGAGKSTLLKALAG--DLTGGGAPRGARVTGDVTLNGEPLAAidaPRLA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 117 TNVGMVFQQPNP-FPKSIYDNITYGPKIHG-------IKNKKVLDEIVEksLRGAaiwDELKDRlhtNAYSLSGGQQQRV 188
Cdd:PRK13547 83 RLRAVLPQAAQPaFAFSAREIVLLGRYPHArragaltHRDGEIAWQALA--LAGA---TALVGR---DVTTLSGGELARV 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 580041203 189 CIARCLA---------IEPEVILMDEPTSALDPISTLRVEELVQELKEKYTI--IMVTHNMQQAARVSDKTAFFLNGYV 256
Cdd:PRK13547 155 QFARVLAqlwpphdaaQPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLgvLAIVHDPNLAARHADRIAMLADGAI 233
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
52-268 |
2.85e-11 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 63.84 E-value: 2.85e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 52 LQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELvpsvkTAGKILYRDQDIfdQKYSKEQLRTNVGMVFQQPNPFPK 131
Cdd:PLN03232 1252 LHGLSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVEL-----EKGRIMIDDCDV--AKFGLTDLRRVLSIIPQSPVLFSG 1324
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 132 SIYDNItygpkihgiknkkvlDEIVEKSlrGAAIWDEL-----KDRLHTNAYSL-----------SGGQQQRVCIARCLA 195
Cdd:PLN03232 1325 TVRFNI---------------DPFSEHN--DADLWEALerahiKDVIDRNPFGLdaevseggenfSVGQRQLLSLARALL 1387
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 580041203 196 IEPEVILMDEPTSALDpistLRVEELVQE-LKEKY---TIIMVTHNMQQAARVsDKTAFFLNGYVNEYDDTDKIFSN 268
Cdd:PLN03232 1388 RRSKILVLDEATASVD----VRTDSLIQRtIREEFkscTMLVIAHRLNTIIDC-DKILVLSSGQVLEYDSPQELLSR 1459
|
|
| ABCC_CFTR1 |
cd03291 |
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ... |
52-254 |
5.92e-11 |
|
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213258 [Multi-domain] Cd Length: 282 Bit Score: 61.80 E-value: 5.92e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 52 LQNINLDIYENQITAIIGPSGCGKSTYIKTLnrMVELVPSvktAGKILYRDQDIFDQKYSKeqlrtnvgmvfqqpnPFPK 131
Cdd:cd03291 53 LKNINLKIEKGEMLAITGSTGSGKTSLLMLI--LGELEPS---EGKIKHSGRISFSSQFSW---------------IMPG 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 132 SIYDNITYGPKIHGIKNKKVLDEI-VEKSLrgAAIWDELKDRLHTNAYSLSGGQQQRVCIARCLAIEPEVILMDEPTSAL 210
Cdd:cd03291 113 TIKENIIFGVSYDEYRYKSVVKACqLEEDI--TKFPEKDNTVLGEGGITLSGGQRARISLARAVYKDADLYLLDSPFGYL 190
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 580041203 211 DPISTLRV-EELVQELKEKYTIIMVTHNMQQaARVSDKTAFFLNG 254
Cdd:cd03291 191 DVFTEKEIfESCVCKLMANKTRILVTSKMEH-LKKADKILILHEG 234
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
24-256 |
5.99e-11 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 62.44 E-value: 5.99e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 24 HKTPDDTNS-HSVIYSTQNLDLWygENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILYRD 102
Cdd:PRK10982 237 QRFPDKENKpGEVILEVRNLTSL--RQPSIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIRE-----KSAGTITLHG 309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 103 QDIfDQKYSKEQLRTNVGMVFQQPNPfpKSIYDN--ITYGPKIHGIKNKK----VLDEIVEKSLRGAAIwDELKDRL--- 173
Cdd:PRK10982 310 KKI-NNHNANEAINHGFALVTEERRS--TGIYAYldIGFNSLISNIRNYKnkvgLLDNSRMKSDTQWVI-DSMRVKTpgh 385
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 174 HTNAYSLSGGQQQRVCIARCLAIEPEVILMDEPTSALDPISTLRVEELVQEL-KEKYTIIMVTHNMQQAARVSDKTAFFL 252
Cdd:PRK10982 386 RTQIGSLSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIAELaKKDKGIIIISSEMPELLGITDRILVMS 465
|
....
gi 580041203 253 NGYV 256
Cdd:PRK10982 466 NGLV 469
|
|
| ABC_UvrA |
cd03238 |
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ... |
50-246 |
7.63e-11 |
|
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213205 [Multi-domain] Cd Length: 176 Bit Score: 59.64 E-value: 7.63e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 50 HALQNINLDIYENQITAIIGPSGCGKSTYIKTlnrmvelvpSVKTAGKILYRDqdiFDQKYSKE------QLRTNVGMvf 123
Cdd:cd03238 9 HNLQNLDVSIPLNVLVVVTGVSGSGKSTLVNE---------GLYASGKARLIS---FLPKFSRNklifidQLQFLIDV-- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 124 qqpnpfpksiydNITYGPkihgiknkkvldeivekslrgaaiwdelkdrLHTNAYSLSGGQQQRVCIARCLAIEPE--VI 201
Cdd:cd03238 75 ------------GLGYLT-------------------------------LGQKLSTLSGGELQRVKLASELFSEPPgtLF 111
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 580041203 202 LMDEPTSALDPISTLRVEELVQEL-KEKYTIIMVTHN---MQQAARVSD 246
Cdd:cd03238 112 ILDEPSTGLHQQDINQLLEVIKGLiDLGNTVILIEHNldvLSSADWIID 160
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
47-258 |
7.95e-11 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 62.45 E-value: 7.95e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 47 GENHALQNINLDIYENQITAIIGPSGCGKSTYIKTlnrMVELVPSVKTAGKIlyrdqdifdqkyskeqLRTNVGMVFQQP 126
Cdd:PLN03130 628 AERPTLSNINLDVPVGSLVAIVGSTGEGKTSLISA---MLGELPPRSDASVV----------------IRGTVAYVPQVS 688
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 127 NPFPKSIYDNITYGPKIHGIKNKKVLD-----------------EIVEkslRGAAIwdelkdrlhtnayslSGGQQQRVC 189
Cdd:PLN03130 689 WIFNATVRDNILFGSPFDPERYERAIDvtalqhdldllpggdltEIGE---RGVNI---------------SGGQKQRVS 750
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 580041203 190 IARCLAIEPEVILMDEPTSALDPISTLRVEE--LVQELKEKyTIIMVTHNMQQAARVsDKTAFFLNGYVNE 258
Cdd:PLN03130 751 MARAVYSNSDVYIFDDPLSALDAHVGRQVFDkcIKDELRGK-TRVLVTNQLHFLSQV-DRIILVHEGMIKE 819
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
52-254 |
8.93e-11 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 62.24 E-value: 8.93e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 52 LQNINLDIYENQITAIIGPSGCGKSTYIKTLnrMVELVPS---VKTAGKILYRDQdifdqkyskeqlrtnvgmvfqQPNP 128
Cdd:TIGR01271 442 LKNISFKLEKGQLLAVAGSTGSGKSSLLMMI--MGELEPSegkIKHSGRISFSPQ---------------------TSWI 498
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 129 FPKSIYDNITYGPKIHGIKNKKVLDEI-VEKSLrgAAIWDELKDRLHTNAYSLSGGQQQRVCIARCLAIEPEVILMDEPT 207
Cdd:TIGR01271 499 MPGTIKDNIIFGLSYDEYRYTSVIKACqLEEDI--ALFPEKDKTVLGEGGITLSGGQRARISLARAVYKDADLYLLDSPF 576
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 580041203 208 SALDPISTLRV-EELVQELKEKYTIIMVTHNMQQAARvSDKTAFFLNG 254
Cdd:TIGR01271 577 THLDVVTEKEIfESCLCKLMSNKTRILVTSKLEHLKK-ADKILLLHEG 623
|
|
| znuC |
PRK09544 |
high-affinity zinc transporter ATPase; Reviewed |
34-238 |
1.31e-10 |
|
high-affinity zinc transporter ATPase; Reviewed
Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 60.13 E-value: 1.31e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 34 SVIYSTQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILYrdqdifdqkysKE 113
Cdd:PRK09544 2 TSLVSLENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVA-----PDEGVIKR-----------NG 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 114 QLRtnVGMVFQQPN---PFPKSIYDNITYGPkihGIKNKKVLDEIveKSLRGAAIWDELKDRLhtnayslSGGQQQRVCI 190
Cdd:PRK09544 66 KLR--IGYVPQKLYldtTLPLTVNRFLRLRP---GTKKEDILPAL--KRVQAGHLIDAPMQKL-------SGGETQRVLL 131
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 580041203 191 ARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEK--YTIIMVTHNM 238
Cdd:PRK09544 132 ARALLNRPQLLVLDEPTQGVDVNGQVALYDLIDQLRREldCAVLMVSHDL 181
|
|
| ABCC_CFTR2 |
cd03289 |
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ... |
47-270 |
1.59e-10 |
|
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213256 [Multi-domain] Cd Length: 275 Bit Score: 60.25 E-value: 1.59e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 47 GENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELVPSVKTAGkilyrdqdIFDQKYSKEQLRTNVGMVFQQP 126
Cdd:cd03289 15 GGNAVLENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLNTEGDIQIDG--------VSWNSVPLQKWRKAFGVIPQKV 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 127 NPFPKSIYDNITYGPKIHGIKNKKVLDEIVEKSLRgAAIWDELKDRLHTNAYSLSGGQQQRVCIARCLAIEPEVILMDEP 206
Cdd:cd03289 87 FIFSGTFRKNLDPYGKWSDEEIWKVAEEVGLKSVI-EQFPGQLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEP 165
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 580041203 207 TSALDPISTLRVEELVQELKEKYTIIMVTHNMQ-----QAARVSDKtafflnGYVNEYDDTDKIFSNPS 270
Cdd:cd03289 166 SAHLDPITYQVIRKTLKQAFADCTVILSEHRIEamlecQRFLVIEE------NKVRQYDSIQKLLNEKS 228
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
66-259 |
2.22e-10 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 60.73 E-value: 2.22e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 66 AIIGPSGCGKSTYIKTLnrMVELVP---SVKTAGK--ILYrdqdiFDQKysKEQLrtnvgmvfqqpNPfPKSIYDNITYG 140
Cdd:PRK11147 349 ALIGPNGCGKTTLLKLM--LGQLQAdsgRIHCGTKleVAY-----FDQH--RAEL-----------DP-EKTVMDNLAEG 407
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 141 PK---IHGIKnKKVLDEivekslrgaaiwdeLKD------RLHTNAYSLSGGQQQRVCIARCLAIEPEVILMDEPTSALD 211
Cdd:PRK11147 408 KQevmVNGRP-RHVLGY--------------LQDflfhpkRAMTPVKALSGGERNRLLLARLFLKPSNLLILDEPTNDLD 472
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 580041203 212 pISTLrveELVQELKEKY--TIIMVTHNMQqaarVSDKTA-----FFLNGYVNEY 259
Cdd:PRK11147 473 -VETL---ELLEELLDSYqgTVLLVSHDRQ----FVDNTVtecwiFEGNGKIGRY 519
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
40-239 |
2.96e-10 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 60.69 E-value: 2.96e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGE--NHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvkTAGKIlyRDQDIFDQKYSKEQLRT 117
Cdd:TIGR01271 1221 QGLTAKYTEagRAVLQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRLLS------TEGEI--QIDGVSWNSVTLQTWRK 1292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 118 NVGMVFQQPNPFPKSIYDNITYGPKIHGIKNKKVLDEIVEKSLRgAAIWDELKDRLHTNAYSLSGGQQQRVCIARCLAIE 197
Cdd:TIGR01271 1293 AFGVIPQKVFIFSGTFRKNLDPYEQWSDEEIWKVAEEVGLKSVI-EQFPDKLDFVLVDGGYVLSNGHKQLMCLARSILSK 1371
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 580041203 198 PEVILMDEPTSALDPIsTLRVeeLVQELKEKY---TIIMVTHNMQ 239
Cdd:TIGR01271 1372 AKILLLDEPSAHLDPV-TLQI--IRKTLKQSFsncTVILSEHRVE 1413
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
52-268 |
3.79e-10 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 60.52 E-value: 3.79e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 52 LQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELvpsvkTAGKILYRDQDIfdQKYSKEQLRTNVGMVFQQPNPFPK 131
Cdd:PLN03130 1255 LHGLSFEISPSEKVGIVGRTGAGKSSMLNALFRIVEL-----ERGRILIDGCDI--SKFGLMDLRKVLGIIPQAPVLFSG 1327
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 132 SIYDNitygpkihgiknkkvLDEIVEKSlrGAAIWD-----ELKDRLHTNAYSL-----------SGGQQQRVCIARCLA 195
Cdd:PLN03130 1328 TVRFN---------------LDPFNEHN--DADLWEsleraHLKDVIRRNSLGLdaevseagenfSVGQRQLLSLARALL 1390
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 580041203 196 IEPEVILMDEPTSALDpistLRVEELVQE-LKEKY---TIIMVTHNMQQAARvSDKTAFFLNGYVNEYDDTDKIFSN 268
Cdd:PLN03130 1391 RRSKILVLDEATAAVD----VRTDALIQKtIREEFkscTMLIIAHRLNTIID-CDRILVLDAGRVVEFDTPENLLSN 1462
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
47-238 |
4.09e-10 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 60.34 E-value: 4.09e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 47 GENHALQNINLDIYENQITAIIGPSGCGKSTYIKTL-NRMVELVPSVKTAGKILYRDQDIFDQKYSkeqLRTNVGMVFQQ 125
Cdd:TIGR00957 649 DLPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALlAEMDKVEGHVHMKGSVAYVPQQAWIQNDS---LRENILFGKAL 725
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 126 PNPFPKSIYDNITYGPKIHGIKNKKvLDEIVEKSLrgaaiwdelkdrlhtnaySLSGGQQQRVCIARCLAIEPEVILMDE 205
Cdd:TIGR00957 726 NEKYYQQVLEACALLPDLEILPSGD-RTEIGEKGV------------------NLSGGQKQRVSLARAVYSNADIYLFDD 786
|
170 180 190
....*....|....*....|....*....|....*..
gi 580041203 206 PTSALDPISTLRVEELV----QELKEKyTIIMVTHNM 238
Cdd:TIGR00957 787 PLSAVDAHVGKHIFEHVigpeGVLKNK-TRILVTHGI 822
|
|
| PLN03211 |
PLN03211 |
ABC transporter G-25; Provisional |
63-244 |
4.19e-10 |
|
ABC transporter G-25; Provisional
Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 59.89 E-value: 4.19e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 63 QITAIIGPSGCGKSTYiktLNRMVELVPSVKTAGKILyrdqdIFDQKYSKEQLRtNVGMVFQQPNPFP------KSIYDN 136
Cdd:PLN03211 95 EILAVLGPSGSGKSTL---LNALAGRIQGNNFTGTIL-----ANNRKPTKQILK-RTGFVTQDDILYPhltvreTLVFCS 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 137 ITYGPKIHGIKNKKVLDEIVEKSLrGAAiwdELKDRLHTNAY--SLSGGQQQRVCIARCLAIEPEVILMDEPTSALDPIS 214
Cdd:PLN03211 166 LLRLPKSLTKQEKILVAESVISEL-GLT---KCENTIIGNSFirGISGGERKRVSIAHEMLINPSLLILDEPTSGLDATA 241
|
170 180 190
....*....|....*....|....*....|
gi 580041203 215 TLRVEELVQELKEKYTIImVTHNMQQAARV 244
Cdd:PLN03211 242 AYRLVLTLGSLAQKGKTI-VTSMHQPSSRV 270
|
|
| sufC |
PRK09580 |
cysteine desulfurase ATPase component; Reviewed |
38-236 |
7.24e-10 |
|
cysteine desulfurase ATPase component; Reviewed
Pssm-ID: 181965 [Multi-domain] Cd Length: 248 Bit Score: 57.88 E-value: 7.24e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 38 STQNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELvpsVKTAGKILYRDQDIFDQKySKEQLRT 117
Cdd:PRK09580 3 SIKDLHVSVEDKAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGREDY---EVTGGTVEFKGKDLLELS-PEDRAGE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 118 NVGMVFQQPNPFPksiydnitygpkihGIKNKKVLDEIVE--KSLRGAAIWD---------------ELKDRLHTNAYSL 180
Cdd:PRK09580 79 GIFMAFQYPVEIP--------------GVSNQFFLQTALNavRSYRGQEPLDrfdfqdlmeekiallKMPEDLLTRSVNV 144
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 181 --SGGQQQRVCIARCLAIEPEVILMDEPTSALDpISTLR-VEELVQELK-EKYTIIMVTH 236
Cdd:PRK09580 145 gfSGGEKKRNDILQMAVLEPELCILDESDSGLD-IDALKiVADGVNSLRdGKRSFIIVTH 203
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
35-247 |
7.73e-10 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 59.07 E-value: 7.73e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 35 VIYSTQNLDLWYGENHALQ---NINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsVKTAGKIlYRDQDIFDQKYS 111
Cdd:TIGR02633 256 VILEARNLTCWDVINPHRKrvdDVSFSLRRGEILGVAGLVGAGRTELVQALFGAYP----GKFEGNV-FINGKPVDIRNP 330
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 112 KEQLRTNVGMVfqqPNPFPK-------SIYDNITYGpKIHGIKNKKVLDEIVEKSLRGAAIwdelkDRLHTNAYS----- 179
Cdd:TIGR02633 331 AQAIRAGIAMV---PEDRKRhgivpilGVGKNITLS-VLKSFCFKMRIDAAAELQIIGSAI-----QRLKVKTASpflpi 401
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 580041203 180 --LSGGQQQRVCIARCLAIEPEVILMDEPTSALDPISTLRVEELVQEL-KEKYTIIMVTHNMQQAARVSDK 247
Cdd:TIGR02633 402 grLSGGNQQKAVLAKMLLTNPRVLILDEPTRGVDVGAKYEIYKLINQLaQEGVAIIVVSSELAEVLGLSDR 472
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
51-248 |
8.31e-10 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 59.03 E-value: 8.31e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 51 ALQNINLDIYENQITAIIGPSGCGKSTYIKTLNrmvELVPSVKTAGKILYRDQ-----DIFDQkyskEQLrtnvGMVF-- 123
Cdd:NF040905 16 ALDDVNLSVREGEIHALCGENGAGKSTLMKVLS---GVYPHGSYEGEILFDGEvcrfkDIRDS----EAL----GIVIih 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 124 QQPNPFPK-SIYDNITYGpkihgikNkkvldeivEKSLRGAAIWDE-------------LKDRLHTNAYSLSGGQQQRVC 189
Cdd:NF040905 85 QELALIPYlSIAENIFLG-------N--------ERAKRGVIDWNEtnrrarellakvgLDESPDTLVTDIGVGKQQLVE 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 190 IARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEK-YTIIMVTHNMQQAARVSDKT 248
Cdd:NF040905 150 IAKALSKDVKLLILDEPTAALNEEDSAALLDLLLELKAQgITSIIISHKLNEIRRVADSI 209
|
|
| ABCG_PDR_domain1 |
cd03233 |
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ... |
52-226 |
8.59e-10 |
|
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 57.27 E-value: 8.59e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 52 LQNINLDIYENQITAIIGPSGCGKSTYIKTLNrmVELVPSVKTAGKILYR--DQDIFDQKYSKEqlrtnVGMVFQQPNPF 129
Cdd:cd03233 23 LKDFSGVVKPGEMVLVLGRPGSGCSTLLKALA--NRTEGNVSVEGDIHYNgiPYKEFAEKYPGE-----IIYVSEEDVHF 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 130 PksiydNITygpkihgiknkkvldeiVEKSLRGAAiwdelkdRLHTNAYS--LSGGQQQRVCIARCLAIEPEVILMDEPT 207
Cdd:cd03233 96 P-----TLT-----------------VRETLDFAL-------RCKGNEFVrgISGGERKRVSIAEALVSRASVLCWDNST 146
|
170
....*....|....*....
gi 580041203 208 SALDPISTLrveELVQELK 226
Cdd:cd03233 147 RGLDSSTAL---EILKCIR 162
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
48-268 |
1.34e-09 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 58.83 E-value: 1.34e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 48 ENHALQNINLDIYENQITAIIGPSGCGKSTYIKTlnrMVELVPSVKTAGKILyrdqdifdqkyskeqlRTNVGMVFQQPN 127
Cdd:PLN03232 629 SKPTLSDINLEIPVGSLVAIVGGTGEGKTSLISA---MLGELSHAETSSVVI----------------RGSVAYVPQVSW 689
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 128 PFPKSIYDNITYGPKIHGIKNKKVLDEIV---EKSLRGAAIWDELKDRlhtnAYSLSGGQQQRVCIARCLAIEPEVILMD 204
Cdd:PLN03232 690 IFNATVRENILFGSDFESERYWRAIDVTAlqhDLDLLPGRDLTEIGER----GVNISGGQKQRVSMARAVYSNSDIYIFD 765
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 580041203 205 EPTSALDPISTLRVEE--LVQELKEKyTIIMVTHNMQQAARVsDKTAFFLNGYVNEYDDTDKIFSN 268
Cdd:PLN03232 766 DPLSALDAHVAHQVFDscMKDELKGK-TRVLVTNQLHFLPLM-DRIILVSEGMIKEEGTFAELSKS 829
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
173-278 |
1.48e-09 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 58.26 E-value: 1.48e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 173 LHTNAYSLSGGQQQRVCIARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEK-YTIIMVTHNMQQAARVSDKTAFF 251
Cdd:PRK09700 403 VNQNITELSGGNQQKVLISKWLCCCPEVIIFDEPTRGIDVGAKAEIYKVMRQLADDgKVILMVSSELPEIITVCDRIAVF 482
|
90 100
....*....|....*....|....*..
gi 580041203 252 LNGYVNEyddtdkIFSNpSNKKTEDYI 278
Cdd:PRK09700 483 CEGRLTQ------ILTN-RDDMSEEEI 502
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
52-258 |
1.79e-09 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 58.25 E-value: 1.79e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 52 LQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELVpsvktAGKILYRDQDIfdQKYSKEQLRTNVGMVFQQPNPFPK 131
Cdd:PTZ00243 1326 LRGVSFRIAPREKVGIVGRTGSGKSTLLLTFMRMVEVC-----GGEIRVNGREI--GAYGLRELRRQFSMIPQDPVLFDG 1398
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 132 SIYDNitygpkihgiknkkvLDEIVEKSlrGAAIWDELK----------------DRLHTNAYSLSGGQQQRVCIARCLA 195
Cdd:PTZ00243 1399 TVRQN---------------VDPFLEAS--SAEVWAALElvglrervasesegidSRVLEGGSNYSVGQRQLMCMARALL 1461
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 580041203 196 IEPE-VILMDEPTSALDPISTLRVEELVQELKEKYTIIMVTHNMQQAARVsDKTAFFLNGYVNE 258
Cdd:PTZ00243 1462 KKGSgFILMDEATANIDPALDRQIQATVMSAFSAYTVITIAHRLHTVAQY-DKIIVMDHGAVAE 1524
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
51-247 |
2.15e-09 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 57.63 E-value: 2.15e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 51 ALQNINLDIYENQITAIIGPSGCGKSTYIKTLNrmvELVPSVKTAGKILYRDQDIfdQKYS-KEQLRTNVGMVFQQPNPF 129
Cdd:PRK13549 20 ALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLS---GVYPHGTYEGEIIFEGEEL--QASNiRDTERAGIAIIHQELALV 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 130 PK-SIYDNITYGPKI--HGIKNkkvLDEIVeksLRGAAIWDELKdrLHTNAYS----LSGGQQQRVCIARCLAIEPEVIL 202
Cdd:PRK13549 95 KElSVLENIFLGNEItpGGIMD---YDAMY---LRAQKLLAQLK--LDINPATpvgnLGLGQQQLVEIAKALNKQARLLI 166
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 580041203 203 MDEPTSALDPISTLRVEELVQELKEK-YTIIMVTHNMQQAARVSDK 247
Cdd:PRK13549 167 LDEPTASLTESETAVLLDIIRDLKAHgIACIYISHKLNEVKAISDT 212
|
|
| ABC_UvrA_I |
cd03270 |
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair ... |
50-246 |
2.17e-09 |
|
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213237 [Multi-domain] Cd Length: 226 Bit Score: 56.50 E-value: 2.17e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 50 HALQNINLDIYENQITAIIGPSGCGKST------YIKTLNRMVELVPSVKTAGKILYRDQDI-----------FDQKYSK 112
Cdd:cd03270 9 HNLKNVDVDIPRNKLVVITGVSGSGKSSlafdtiYAEGQRRYVESLSAYARQFLGQMDKPDVdsieglspaiaIDQKTTS 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 113 EQLRTNVGMVfQQPNPFPKSIYDNItygpkihGIKNKkvLDEIVEKSLrgaaiwDELkdRLHTNAYSLSGGQQQRVCIAR 192
Cdd:cd03270 89 RNPRSTVGTV-TEIYDYLRLLFARV-------GIRER--LGFLVDVGL------GYL--TLSRSAPTLSGGEAQRIRLAT 150
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 193 CLAIEPEVIL--MDEPTSALDPISTLRVEELVQELKEK-YTIIMVTHN---MQQAARVSD 246
Cdd:cd03270 151 QIGSGLTGVLyvLDEPSIGLHPRDNDRLIETLKRLRDLgNTVLVVEHDedtIRAADHVID 210
|
|
| ABCC_SUR2 |
cd03288 |
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ... |
40-267 |
4.19e-09 |
|
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213255 [Multi-domain] Cd Length: 257 Bit Score: 56.07 E-value: 4.19e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGEN--HALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELVPsvktaGKILYRDQDIfdQKYSKEQLRT 117
Cdd:cd03288 23 HDLCVRYENNlkPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFD-----GKIVIDGIDI--SKLPLHTLRS 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 118 NVGMVFQQPNPFPKSIYDNITygpkihgiKNKKVLDEIVEKSLRGAAIWDELK------DRLHTNA-YSLSGGQQQRVCI 190
Cdd:cd03288 96 RLSIILQDPILFSGSIRFNLD--------PECKCTDDRLWEALEIAQLKNMVKslpgglDAVVTEGgENFSVGQRQLFCL 167
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 580041203 191 ARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEKYTIIMVTHNMQQAARvSDKTAFFLNGYVNEYDDTDKIFS 267
Cdd:cd03288 168 ARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVSTILD-ADLVLVLSRGILVECDTPENLLA 243
|
|
| 3a01204 |
TIGR00955 |
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ... |
47-236 |
5.48e-09 |
|
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 56.59 E-value: 5.48e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 47 GENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLnrMVELVPSVKTAGKILyrdqdIFDQKYSKEQLRTNVGMVFQQP 126
Cdd:TIGR00955 36 PRKHLLKNVSGVAKPGELLAVMGSSGAGKTTLMNAL--AFRSPKGVKGSGSVL-----LNGMPIDAKEMRAISAYVQQDD 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 127 NPFPK-SIYDNITYGPKI----HGIKNKKVL--DEIVEK-SLRGAA-----IWDELKdrlhtnaySLSGGQQQRVCIARC 193
Cdd:TIGR00955 109 LFIPTlTVREHLMFQAHLrmprRVTKKEKRErvDEVLQAlGLRKCAntrigVPGRVK--------GLSGGERKRLAFASE 180
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 580041203 194 LAIEPEVILMDEPTSALDPISTLRVEELVQELKEK-YTIIMVTH 236
Cdd:TIGR00955 181 LLTDPPLLFCDEPTSGLDSFMAYSVVQVLKGLAQKgKTIICTIH 224
|
|
| ABCG_PDR_domain2 |
cd03232 |
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ... |
52-225 |
1.05e-08 |
|
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 53.79 E-value: 1.05e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 52 LQNINLDIYENQITAIIGPSGCGKSTYIKTL-NRmvelvpsvKTAGKIlyrDQDIF-DQKYSKEQLRTNVGMVFQQPNPF 129
Cdd:cd03232 23 LNNISGYVKPGTLTALMGESGAGKTTLLDVLaGR--------KTAGVI---TGEILiNGRPLDKNFQRSTGYVEQQDVHS 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 130 PKSIydnitygpkihgiknkkvldeiVEKSLRgaaiwdelkdrLHTNAYSLSGGQQQRVCIARCLAIEPEVILMDEPTSA 209
Cdd:cd03232 92 PNLT----------------------VREALR-----------FSALLRGLSVEQRKRLTIGVELAAKPSILFLDEPTSG 138
|
170
....*....|....*.
gi 580041203 210 LDPISTLRVEELVQEL 225
Cdd:cd03232 139 LDSQAAYNIVRFLKKL 154
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
54-247 |
2.16e-08 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 54.67 E-value: 2.16e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 54 NINLDIYENQITAIIGPSGCGKSTYIKTLnrmVELVPsvKTAGKILYRDQDIfdQKYSKEQlRTNVGMVF-----QQPNP 128
Cdd:PRK15439 281 NISLEVRAGEILGLAGVVGAGRTELAETL---YGLRP--ARGGRIMLNGKEI--NALSTAQ-RLARGLVYlpedrQSSGL 352
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 129 F-PKSIYDNI---TYGPK---IHGIKNKKVLdeivEKSLRGAAIWDELKDRlhtNAYSLSGGQQQRVCIARCLAIEPEVI 201
Cdd:PRK15439 353 YlDAPLAWNVcalTHNRRgfwIKPARENAVL----ERYRRALNIKFNHAEQ---AARTLSGGNQQKVLIAKCLEASPQLL 425
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 580041203 202 LMDEPTSALDPISTLRVEELVQELKEKYT-IIMVTHNMQQAARVSDK 247
Cdd:PRK15439 426 IVDEPTRGVDVSARNDIYQLIRSIAAQNVaVLFISSDLEEIEQMADR 472
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
180-247 |
3.30e-08 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 54.24 E-value: 3.30e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 580041203 180 LSGGQQQRVCIARCLAIEPEVILMDEPTSALDPISTLRVEELVQELK-EKYTIIMVTHNMQQAARVSDK 247
Cdd:PRK10762 396 LSGGNQQKVAIARGLMTRPKVLILDEPTRGVDVGAKKEIYQLINQFKaEGLSIILVSSEMPEVLGMSDR 464
|
|
| 3a01203 |
TIGR00954 |
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ... |
52-236 |
4.46e-08 |
|
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 273360 [Multi-domain] Cd Length: 659 Bit Score: 53.98 E-value: 4.46e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 52 LQNINLDIYENQITAIIGPSGCGKSTYIKTLNrmvELVPsvkTAGKILY--RDQDIFdqkyskeqlrtnvgMVFQQPNPF 129
Cdd:TIGR00954 468 IESLSFEVPSGNNLLICGPNGCGKSSLFRILG---ELWP---VYGGRLTkpAKGKLF--------------YVPQRPYMT 527
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 130 PKSIYDNITYGPKIHGIKNKKVLDEIVEKSL----------RGAAiWDELKDRLHTnaysLSGGQQQRVCIARCLAIEPE 199
Cdd:TIGR00954 528 LGTLRDQIIYPDSSEDMKRRGLSDKDLEQILdnvqlthileREGG-WSAVQDWMDV----LSGGEKQRIAMARLFYHKPQ 602
|
170 180 190
....*....|....*....|....*....|....*....
gi 580041203 200 VILMDEPTSALDPistlRVEELVQELKEKY--TIIMVTH 236
Cdd:TIGR00954 603 FAILDECTSAVSV----DVEGYMYRLCREFgiTLFSVSH 637
|
|
| PRK13546 |
PRK13546 |
teichoic acids export ABC transporter ATP-binding subunit TagH; |
50-265 |
4.57e-08 |
|
teichoic acids export ABC transporter ATP-binding subunit TagH;
Pssm-ID: 184131 [Multi-domain] Cd Length: 264 Bit Score: 52.90 E-value: 4.57e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 50 HALQNINLDIYENQITAIIGPSGCGKSTyiktLNRMV--ELVPsvkTAGKIlYRDQDIfdqkyskEQLRTNVGMVFQQPN 127
Cdd:PRK13546 38 FALDDISLKAYEGDVIGLVGINGSGKST----LSNIIggSLSP---TVGKV-DRNGEV-------SVIAISAGLSGQLTG 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 128 pfpksiYDNITYGPKIHGIKNK---KVLDEIVEKSlrgaaiwdELKDRLHTNAYSLSGGQQQRVCIARCLAIEPEVILMD 204
Cdd:PRK13546 103 ------IENIEFKMLCMGFKRKeikAMTPKIIEFS--------ELGEFIYQPVKKYSSGMRAKLGFSINITVNPDILVID 168
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 580041203 205 EPTSALDPISTLRVEELVQELKE-KYTIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKI 265
Cdd:PRK13546 169 EALSVGDQTFAQKCLDKIYEFKEqNKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYGELDDV 230
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
46-220 |
7.40e-08 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 53.02 E-value: 7.40e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 46 YGENHALQNINLDIYENQITAIIGPSGCGKStyikTLNRM-----------VELVPSVKTAgkilYRDQdifdqkySKEQ 114
Cdd:TIGR03719 332 FGDKLLIDDLSFKLPPGGIVGVIGPNGAGKS----TLFRMitgqeqpdsgtIEIGETVKLA----YVDQ-------SRDA 396
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 115 LRTNvgmvfqqpnpfpKSIYDNITYGPKIHGIKNKKVLDE--IVEKSLRGAaiwDELKdrlhtNAYSLSGGQQQRVCIAR 192
Cdd:TIGR03719 397 LDPN------------KTVWEEISGGLDIIKLGKREIPSRayVGRFNFKGS---DQQK-----KVGQLSGGERNRVHLAK 456
|
170 180
....*....|....*....|....*...
gi 580041203 193 CLAIEPEVILMDEPTSALDpISTLRVEE 220
Cdd:TIGR03719 457 TLKSGGNVLLLDEPTNDLD-VETLRALE 483
|
|
| tagH |
PRK13545 |
teichoic acids export protein ATP-binding subunit; Provisional |
47-268 |
9.43e-08 |
|
teichoic acids export protein ATP-binding subunit; Provisional
Pssm-ID: 184130 [Multi-domain] Cd Length: 549 Bit Score: 52.97 E-value: 9.43e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 47 GENH-ALQNINLDIYENQITAIIGPSGCGKSTyiktLNRMVELVpSVKTAGKIlyrdqdifDQKYSKEQLRTNVGMVFQQ 125
Cdd:PRK13545 34 GEYHyALNNISFEVPEGEIVGIIGLNGSGKST----LSNLIAGV-TMPNKGTV--------DIKGSAALIAISSGLNGQL 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 126 pnpfpkSIYDNITYGPKIHGIKNKKVlDEIVEKSLRGAaiwdELKDRLHTNAYSLSGGQQQRVCIARCLAIEPEVILMDE 205
Cdd:PRK13545 101 ------TGIENIELKGLMMGLTKEKI-KEIIPEIIEFA----DIGKFIYQPVKTYSSGMKSRLGFAISVHINPDILVIDE 169
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 580041203 206 PTSALDPISTLRVEELVQELKEK-YTIIMVTHNMQQAARVSDKTAFFLNGYVNEYDDTDKIFSN 268
Cdd:PRK13545 170 ALSVGDQTFTKKCLDKMNEFKEQgKTIFFISHSLSQVKSFCTKALWLHYGQVKEYGDIKEVVDH 233
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
35-236 |
1.55e-07 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 52.04 E-value: 1.55e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 35 VIYSTQNLDLWYGEN-HALQNINLDIYENQITAIIGPSGCGKSTYIKTLnrmvelvpsvktAGkilyrdqdiFDQKYSKE 113
Cdd:PRK11819 5 YIYTMNRVSKVVPPKkQILKDISLSFFPGAKIGVLGLNGAGKSTLLRIM------------AG---------VDKEFEGE 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 114 ---QLRTNVGMVFQQP--NPfPKSIYDNITYGpkIHGIKNK-KVLDEIVEKSLRGAAIWDELKDRL--------HTNAY- 178
Cdd:PRK11819 64 arpAPGIKVGYLPQEPqlDP-EKTVRENVEEG--VAEVKAAlDRFNEIYAAYAEPDADFDALAAEQgelqeiidAADAWd 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 179 ----------------------SLSGGQQQRVCIARCLAIEPEVILMDEPTSALDPIStlrVEELVQELKE-KYTIIMVT 235
Cdd:PRK11819 141 ldsqleiamdalrcppwdakvtKLSGGERRRVALCRLLLEKPDMLLLDEPTNHLDAES---VAWLEQFLHDyPGTVVAVT 217
|
.
gi 580041203 236 H 236
Cdd:PRK11819 218 H 218
|
|
| ABC_UvrA_II |
cd03271 |
ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair ... |
50-238 |
1.76e-07 |
|
ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213238 [Multi-domain] Cd Length: 261 Bit Score: 51.08 E-value: 1.76e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 50 HALQNINLDIYENQITAIIGPSGCGKSTYIKTLnrmveLVPSVKTagkILYRDQDIFDQKYSKEQLR--TNVGMVFQQP- 126
Cdd:cd03271 9 NNLKNIDVDIPLGVLTCVTGVSGSGKSSLINDT-----LYPALAR---RLHLKKEQPGNHDRIEGLEhiDKVIVIDQSPi 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 127 ------NPFP-KSIYDNI--TYGPKIHGiknKKVLDEIVEKSLRGAAIWDEL-----------------KDRLHT----- 175
Cdd:cd03271 81 grtprsNPATyTGVFDEIreLFCEVCKG---KRYNRETLEVRYKGKSIADVLdmtveealeffenipkiARKLQTlcdvg 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 580041203 176 --------NAYSLSGGQQQRVCIARCL---AIEPEVILMDEPTSALDPISTLRVEELVQELKEK-YTIIMVTHNM 238
Cdd:cd03271 158 lgyiklgqPATTLSGGEAQRIKLAKELskrSTGKTLYILDEPTTGLHFHDVKKLLEVLQRLVDKgNTVVVIEHNL 232
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
179-247 |
2.50e-07 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 51.47 E-value: 2.50e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 179 SLSGGQQQRVCIARCLAIEPEVILMDEPTSALDPISTLRVEELVQEL-KEKYTIIMVTHNMQQAARVSDK 247
Cdd:PRK13549 405 RLSGGNQQKAVLAKCLLLNPKILILDEPTRGIDVGAKYEIYKLINQLvQQGVAIIVISSELPEVLGLSDR 474
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
67-236 |
2.93e-07 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 51.40 E-value: 2.93e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 67 IIGPSGCGKSTYIKTLnrMVELVPSVKTAGKILYRDQDI-----------FDQKYSKEQLRTNVGMVFQQPNPFPKSIYD 135
Cdd:PLN03073 208 LVGRNGTGKTTFLRYM--AMHAIDGIPKNCQILHVEQEVvgddttalqcvLNTDIERTQLLEEEAQLVAQQRELEFETET 285
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 136 NITYGPKIHGIKNKKV---LDEIVEK---------SLRGAAIWDELK---DRLHTNAYSLSGGQQQRVCIARCLAIEPEV 200
Cdd:PLN03073 286 GKGKGANKDGVDKDAVsqrLEEIYKRlelidaytaEARAASILAGLSftpEMQVKATKTFSGGWRMRIALARALFIEPDL 365
|
170 180 190
....*....|....*....|....*....|....*.
gi 580041203 201 ILMDEPTSALDPISTLRVEELVqeLKEKYTIIMVTH 236
Cdd:PLN03073 366 LLLDEPTNHLDLHAVLWLETYL--LKWPKTFIVVSH 399
|
|
| ABC_RNaseL_inhibitor |
cd03222 |
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ... |
166-251 |
3.53e-07 |
|
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213189 [Multi-domain] Cd Length: 177 Bit Score: 49.11 E-value: 3.53e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 166 WDELKDRLHTNAYSLSGGQQQRVCIARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKE--KYTIIMVTHNMQQAAR 243
Cdd:cd03222 58 WDGITPVYKPQYIDLSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRLSEegKKTALVVEHDLAVLDY 137
|
....*...
gi 580041203 244 VSDKTAFF 251
Cdd:cd03222 138 LSDRIHVF 145
|
|
| PRK13538 |
PRK13538 |
cytochrome c biogenesis heme-transporting ATPase CcmA; |
47-247 |
3.80e-07 |
|
cytochrome c biogenesis heme-transporting ATPase CcmA;
Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 49.42 E-value: 3.80e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 47 GENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLnrmVELVPSvkTAGKILYRDQDIFDQKyskEQLRTNVGMVFQQP 126
Cdd:PRK13538 12 DERILFSGLSFTLNAGELVQIEGPNGAGKTSLLRIL---AGLARP--DAGEVLWQGEPIRRQR---DEYHQDLLYLGHQP 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 127 npfpkSIYD------NITYGPKIHGiknkkVLDEivekslrgAAIWDEL-----KDRLHTNAYSLSGGQQQRVCIARCLA 195
Cdd:PRK13538 84 -----GIKTeltaleNLRFYQRLHG-----PGDD--------EALWEALaqvglAGFEDVPVRQLSAGQQRRVALARLWL 145
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 580041203 196 IEPEVILMDEPTSALDPISTLRVEELVQE-LKEKYTIIMVTHnmQQAARVSDK 247
Cdd:PRK13538 146 TRAPLWILDEPFTAIDKQGVARLEALLAQhAEQGGMVILTTH--QDLPVASDK 196
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
9-260 |
5.40e-07 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 50.71 E-value: 5.40e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 9 KQISQSHTFDVSQSHHKTPDDTNSHSVIYSTQNLDLWYGE--NHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMV 86
Cdd:TIGR00957 1257 KEYSETEKEAPWQIQETAPPSGWPPRGRVEFRNYCLRYREdlDLVLRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRIN 1336
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 87 ElvpsvKTAGKILYRDQDIfdQKYSKEQLRTNVGMVFQQPNPFPKSIYDNITygpKIHGIKNKKVLDEIVEKSLRG--AA 164
Cdd:TIGR00957 1337 E-----SAEGEIIIDGLNI--AKIGLHDLRFKITIIPQDPVLFSGSLRMNLD---PFSQYSDEEVWWALELAHLKTfvSA 1406
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 165 IWDELKDRLHTNAYSLSGGQQQRVCIARCLAIEPEVILMDEPTSALDpistLRVEELVQELK----EKYTIIMVTHNMQQ 240
Cdd:TIGR00957 1407 LPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVD----LETDNLIQSTIrtqfEDCTVLTIAHRLNT 1482
|
250 260
....*....|....*....|..
gi 580041203 241 aarVSDKTAFFL--NGYVNEYD 260
Cdd:TIGR00957 1483 ---IMDYTRVIVldKGEVAEFG 1501
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
26-237 |
7.83e-07 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 50.24 E-value: 7.83e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 26 TPDDTNSHSVIySTQNLDLWY-GENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRmvELVPSVKTAGKILYRDQD 104
Cdd:PLN03073 499 TPDDRPGPPII-SFSDASFGYpGGPLLFKNLNFGIDLDSRIAMVGPNGIGKSTILKLISG--ELQPSSGTVFRSAKVRMA 575
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 105 IFDQKYSkEQLRTNVGMVFQQPNPFPksiydnitygpkihGIKNKKVLDEIVEKSLRGAAIWDELkdrlhtnaYSLSGGQ 184
Cdd:PLN03073 576 VFSQHHV-DGLDLSSNPLLYMMRCFP--------------GVPEQKLRAHLGSFGVTGNLALQPM--------YTLSGGQ 632
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 580041203 185 QQRVCIARCLAIEPEVILMDEPTSALDPIStlrVEELVQELKE-KYTIIMVTHN 237
Cdd:PLN03073 633 KSRVAFAKITFKKPHILLLDEPSNHLDLDA---VEALIQGLVLfQGGVLMVSHD 683
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
132-232 |
1.15e-06 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 49.40 E-value: 1.15e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 132 SIYDNITyGPKIHGIKNKKVLDEIVEkslRGAAiwDELKDRLHTNAYS-------LSGGQQQRVCIARCLAIEPEVILMD 204
Cdd:NF040905 356 DIKRNIT-LANLGKVSRRGVIDENEE---IKVA--EEYRKKMNIKTPSvfqkvgnLSGGNQQKVVLSKWLFTDPDVLILD 429
|
90 100
....*....|....*....|....*...
gi 580041203 205 EPTSALDpistlrveelVQELKEKYTII 232
Cdd:NF040905 430 EPTRGID----------VGAKYEIYTII 447
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
51-211 |
1.28e-06 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 49.25 E-value: 1.28e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 51 ALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELvpsvkTAGKILYRDQDIfdQKYSKEQL-----------RTNV 119
Cdd:COG3845 273 ALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPP-----ASGSIRLDGEDI--TGLSPRERrrlgvayipedRLGR 345
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 120 GMVfqqPNpFpkSIYDNIT----YGPKI--HGIKNKKVL----DEIVEK-SLRGAAIwdelkdrlHTNAYSLSGGQQQRV 188
Cdd:COG3845 346 GLV---PD-M--SVAENLIlgryRRPPFsrGGFLDRKAIrafaEELIEEfDVRTPGP--------DTPARSLSGGNQQKV 411
|
170 180
....*....|....*....|...
gi 580041203 189 CIARCLAIEPEVILMDEPTSALD 211
Cdd:COG3845 412 ILARELSRDPKLLIAAQPTRGLD 434
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
40-243 |
2.61e-06 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 48.58 E-value: 2.61e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTyiktlnrMVELVPSVKT--AGKILYRDQDIFDQKYskeqlRT 117
Cdd:NF033858 5 EGVSHRYGKTVALDDVSLDIPAGCMVGLIGPDGVGKSS-------LLSLIAGARKiqQGRVEVLGGDMADARH-----RR 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 118 NVG-----MvfqqP-----NPFPK-SIYDNITYGPKIHGiknkkvLDeiveKSLRGAAIwDEL---------KDRLhtnA 177
Cdd:NF033858 73 AVCpriayM----PqglgkNLYPTlSVFENLDFFGRLFG------QD----AAERRRRI-DELlratglapfADRP---A 134
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 580041203 178 YSLSGGQQQRV--CIArcLAIEPEVILMDEPTSALDPISTLRVEELVQELKEK---YTIIMVTHNMQQAAR 243
Cdd:NF033858 135 GKLSGGMKQKLglCCA--LIHDPDLLILDEPTTGVDPLSRRQFWELIDRIRAErpgMSVLVATAYMEEAER 203
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
46-261 |
2.99e-06 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 47.96 E-value: 2.99e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 46 YGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLnrMVELVP---SVKTA--GKILYRDQD----------IFD--- 107
Cdd:PRK15064 329 FDNGPLFKNLNLLLEAGERLAIIGENGVGKTTLLRTL--VGELEPdsgTVKWSenANIGYYAQDhaydfendltLFDwms 406
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 108 ---QKYSKEQ-LRTNVG-MVFQQpnpfpksiyDNItygpkihgikNKKVldeivekslrgaaiwdelkdrlhtnaYSLSG 182
Cdd:PRK15064 407 qwrQEGDDEQaVRGTLGrLLFSQ---------DDI----------KKSV--------------------------KVLSG 441
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 183 GQQQRVCIARCLAIEPEVILMDEPTSALDPIStlrVEELVQELkEKY--TIIMVTHNMQ----QAARVSDKTAFFLNGYV 256
Cdd:PRK15064 442 GEKGRMLFGKLMMQKPNVLVMDEPTNHMDMES---IESLNMAL-EKYegTLIFVSHDREfvssLATRIIEITPDGVVDFS 517
|
....*
gi 580041203 257 NEYDD 261
Cdd:PRK15064 518 GTYEE 522
|
|
| ABC_SMC_barmotin |
cd03278 |
ATP-binding cassette domain of barmotin, a member of the SMC protein family; Barmotin is a ... |
61-243 |
6.88e-06 |
|
ATP-binding cassette domain of barmotin, a member of the SMC protein family; Barmotin is a tight junction-associated protein expressed in rat epithelial cells which is thought to have an important regulatory role in tight junction barrier function. Barmotin belongs to the SMC protein family. SMC proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).
Pssm-ID: 213245 [Multi-domain] Cd Length: 197 Bit Score: 45.92 E-value: 6.88e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 61 ENQITAIIGPSGCGKSTYIKTLnRMVELVPSVKT--AGKIlyrdQD-IF-DQKYSKEQLRTNVGMVFqqpnpfpksiyDN 136
Cdd:cd03278 21 PPGLTAIVGPNGSGKSNIIDAI-RWVLGEQSAKSlrGEKM----SDvIFaGSETRKPANFAEVTLTF-----------DN 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 137 ITygpKIHGIKNKKVLDEIVE---KSLRgaaiwdelkdRLHtnaySLSGGQQQRVCIARCLAIE-----PEVILmDEPTS 208
Cdd:cd03278 85 SD---GRYSIISQGDVSEIIEapgKKVQ----------RLS----LLSGGEKALTALALLFAIFrvrpsPFCVL-DEVDA 146
|
170 180 190
....*....|....*....|....*....|....*...
gi 580041203 209 ALDPISTLRVEELVQELKEKYTIIMVTHN---MQQAAR 243
Cdd:cd03278 147 ALDDANVERFARLLKEFSKETQFIVITHRkgtMEAADR 184
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
180-247 |
6.89e-06 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 46.83 E-value: 6.89e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 580041203 180 LSGGQQQRVCIARCLAIEPEVILMDEPTSALDPISTLRVEELVQELKEK-YTIIMVTHNMQQAARVSDK 247
Cdd:PRK11288 397 LSGGNQQKAILGRWLSEDMKVILLDEPTRGIDVGAKHEIYNVIYELAAQgVAVLFVSSDLPEVLGVADR 465
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
40-217 |
7.77e-06 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 47.04 E-value: 7.77e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRM-------VELVPSVKTAgkilYRDQdifdqkySK 112
Cdd:PRK11819 328 ENLSKSFGDRLLIDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQeqpdsgtIKIGETVKLA----YVDQ-------SR 396
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 113 EQLrtnvgmvfqQPNpfpKSIYDNITYGpkihgiknkkvLDEIvekslrgaaiwdELKDR-LHTNAY------------- 178
Cdd:PRK11819 397 DAL---------DPN---KTVWEEISGG-----------LDII------------KVGNReIPSRAYvgrfnfkggdqqk 441
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 580041203 179 ---SLSGGQQQRVCIARCLAIEPEVILMDEPTSALDpISTLR 217
Cdd:PRK11819 442 kvgVLSGGERNRLHLAKTLKQGGNVLLLDEPTNDLD-VETLR 482
|
|
| PRK13541 |
PRK13541 |
cytochrome c biogenesis protein CcmA; Provisional |
48-211 |
1.00e-05 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184128 [Multi-domain] Cd Length: 195 Bit Score: 45.25 E-value: 1.00e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 48 ENHALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvpsvKTAGKILYRDQDIFD-QK----YSKEQLRTNVGMV 122
Cdd:PRK13541 12 EQKNLFDLSITFLPSAITYIKGANGCGKSSLLRMIAGIMQ-----PSSGNIYYKNCNINNiAKpyctYIGHNLGLKLEMT 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 123 FQQPNPFPKSIYDNITygpkihgiknkkvldeivekSLRGAAIWDELKDRLHTNAYSLSGGQQQRVCIARCLAIEPEVIL 202
Cdd:PRK13541 87 VFENLKFWSEIYNSAE--------------------TLYAAIHYFKLHDLLDEKCYSLSSGMQKIVAIARLIACQSDLWL 146
|
....*....
gi 580041203 203 MDEPTSALD 211
Cdd:PRK13541 147 LDEVETNLS 155
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
62-237 |
1.22e-05 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 44.29 E-value: 1.22e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 62 NQITAIIGPSGCGKSTYIKTLnrmvelvpsvktAGKILYRDQDIfdqkyskeqlrtnvgmvfqqpnpfpksIYDNITygp 141
Cdd:smart00382 2 GEVILIVGPPGSGKTTLARAL------------ARELGPPGGGV---------------------------IYIDGE--- 39
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 142 kihgiknkkvldeivekSLRGAAIWDELKDRLHTNAYSLSGGQQQRVCIARCLAIEPEVILMDEPTSALDPIST--LRVE 219
Cdd:smart00382 40 -----------------DILEEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEalLLLL 102
|
170 180
....*....|....*....|...
gi 580041203 220 ELVQELKEKY-----TIIMVTHN 237
Cdd:smart00382 103 EELRLLLLLKseknlTVILTTND 125
|
|
| 40850658_otr |
NF000106 |
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit; |
46-258 |
1.58e-05 |
|
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 45.50 E-value: 1.58e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 46 YGENHALQNINLDIYENQITAIIGPSGCGKSTyiktlnrmvELVPSVKTAGKILYRDQDIFDQKYSKEQLRTNVGMvfQQ 125
Cdd:NF000106 23 FGEVKAVDGVDLDVREGTVLGVLGP*GAA**R---------GALPAHV*GPDAGRRPWRF*TWCANRRALRRTIG*--HR 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 126 PnpfpksiydnITYGPK--IHGIKNKKVLDEIVEKSLRGA-AIWDELKDRLHTN------AYSLSGGQQQRVCIARCLAI 196
Cdd:NF000106 92 P----------VR*GRResFSGRENLYMIGR*LDLSRKDArARADELLERFSLTeaagraAAKYSGGMRRRLDLAASMIG 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 580041203 197 EPEVILMDEPTSALDPISTLRV-EELVQELKEKYTIIMVTHNMQQAARVS------DKTAFFLNGYVNE 258
Cdd:NF000106 162 RPAVLYLDEPTTGLDPRTRNEVwDEVRSMVRDGATVLLTTQYMEEAEQLAheltviDRGRVIADGKVDE 230
|
|
| uvra |
TIGR00630 |
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ... |
50-238 |
1.71e-05 |
|
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 46.16 E-value: 1.71e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 50 HALQNINLDIYENQITAIIGPSGCGKSTYI-----KTLNRMVELV-----PSVKTAG-----KILYRDQD---------- 104
Cdd:TIGR00630 622 NNLKNITVSIPLGLFTCITGVSGSGKSTLIndtlyPALANRLNGAktvpgRYTSIEGlehldKVIHIDQSpigrtprsnp 701
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 105 -----IFDQ--------------KYSKEQLRTNV-----------GMVFQQPNPFPksiyDNITYGPKIHGiknKKVLDE 154
Cdd:TIGR00630 702 atytgVFDEirelfaetpeakvrGYTPGRFSFNVkggrceacqgdGVIKIEMHFLP----DVYVPCEVCKG---KRYNRE 774
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 155 IVEKSLRGAAIWD-------ELKD-----------------------RLHTNAYSLSGGQQQRVCIARCL---AIEPEVI 201
Cdd:TIGR00630 775 TLEVKYKGKNIADvldmtveEAYEffeavpsisrklqtlcdvglgyiRLGQPATTLSGGEAQRIKLAKELskrSTGRTLY 854
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 580041203 202 LMDEPTSAL--DPISTLRveELVQELKEK-YTIIMVTHNM 238
Cdd:TIGR00630 855 ILDEPTTGLhfDDIKKLL--EVLQRLVDKgNTVVVIEHNL 892
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
168-243 |
2.08e-05 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 45.89 E-value: 2.08e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 168 ELKDRLHTNAYSLSGGQQQRVCIArcLAI--EPEVILMDEPTSALDPISTLRVEELVQEL--KEKYTIIMVTHNMQQAAR 243
Cdd:NF033858 386 DLADVADALPDSLPLGIRQRLSLA--VAVihKPELLILDEPTSGVDPVARDMFWRLLIELsrEDGVTIFISTHFMNEAER 463
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
167-241 |
3.96e-05 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 44.62 E-value: 3.96e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 167 DELKDRLHTNA-------YSLSGGQQQRVCIARCLAIEPEVILMDEPTSALDPISTLRVEELVQEL-KEKYT-IIMVTHN 237
Cdd:PRK10938 382 QQWLDILGIDKrtadapfHSLSWGQQRLALIVRALVKHPTLLILDEPLQGLDPLNRQLVRRFVDVLiSEGETqLLFVSHH 461
|
....
gi 580041203 238 MQQA 241
Cdd:PRK10938 462 AEDA 465
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
52-243 |
8.23e-05 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 44.00 E-value: 8.23e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 52 LQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVELVP-SVKTAGKILYrdqdifdqkyskeqlrtnvgmVFQQPNPFP 130
Cdd:PTZ00243 676 LRDVSVSVPRGKLTVVLGATGSGKSTLLQSLLSQFEISEgRVWAERSIAY---------------------VPQQAWIMN 734
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 131 KSIYDNITYgpkihgiknkkvLDEIVEKSLRGA-------AIWDELKDRLHTN----AYSLSGGQQQRVCIARCLAIEPE 199
Cdd:PTZ00243 735 ATVRGNILF------------FDEEDAARLADAvrvsqleADLAQLGGGLETEigekGVNLSGGQKARVSLARAVYANRD 802
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 580041203 200 VILMDEPTSALDP-ISTLRVEELVQELKEKYTIIMVTHNMQQAAR 243
Cdd:PTZ00243 803 VYLLDDPLSALDAhVGERVVEECFLGALAGKTRVLATHQVHVVPR 847
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
171-254 |
1.25e-04 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 43.46 E-value: 1.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 171 DRLhtnAYSLSGGQQQRVCIARCLAIEPEVILMDEPTSALDPISTLRV-EELVQELKEKYTIIMVTHNMQQAARVSDKTA 249
Cdd:TIGR01257 2065 DRL---AGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLwNTIVSIIREGRAVVLTSHSMEECEALCTRLA 2141
|
....*
gi 580041203 250 FFLNG 254
Cdd:TIGR01257 2142 IMVKG 2146
|
|
| ABC_Rad50 |
cd03240 |
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ... |
64-236 |
1.57e-04 |
|
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.
Pssm-ID: 213207 [Multi-domain] Cd Length: 204 Bit Score: 41.82 E-value: 1.57e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 64 ITAIIGPSGCGKSTYIKTLNrmVELVPSVKTAGKILYRDQDIFdqkySKEQLRTNVGMVFQQPNpfpksiydnityGPKI 143
Cdd:cd03240 24 LTLIVGQNGAGKTTIIEALK--YALTGELPPNSKGGAHDPKLI----REGEVRAQVKLAFENAN------------GKKY 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 144 HGIKNKKVLDEIV----EKSLrgAAIWDELKdrlhtnaySLSGGQQQ------RVCIARCLAIEPEVILMDEPTSALDPI 213
Cdd:cd03240 86 TITRSLAILENVIfchqGESN--WPLLDMRG--------RCSGGEKVlasliiRLALAETFGSNCGILALDEPTTNLDEE 155
|
170 180
....*....|....*....|....*.
gi 580041203 214 S-TLRVEELVQELKEKYT--IIMVTH 236
Cdd:cd03240 156 NiEESLAEIIEERKSQKNfqLIVITH 181
|
|
| PRK00635 |
PRK00635 |
excinuclease ABC subunit A; Provisional |
179-278 |
1.87e-04 |
|
excinuclease ABC subunit A; Provisional
Pssm-ID: 234806 [Multi-domain] Cd Length: 1809 Bit Score: 42.89 E-value: 1.87e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 179 SLSGGQQQRVCIARCLAIEPEVI--LMDEPTSALDPISTLRVEELVQELKEK-YTIIMVTHNMQQ---AARVSD--KTAF 250
Cdd:PRK00635 476 TLSGGEQERTALAKHLGAELIGItyILDEPSIGLHPQDTHKLINVIKKLRDQgNTVLLVEHDEQMislADRIIDigPGAG 555
|
90 100
....*....|....*....|....*...
gi 580041203 251 FLNGYVnEYDDTDKIFSNPSNKKTEDYI 278
Cdd:PRK00635 556 IFGGEV-LFNGSPREFLAKSDSLTAKYL 582
|
|
| ABC_Class2 |
cd03227 |
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ... |
180-243 |
3.70e-04 |
|
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.
Pssm-ID: 213194 [Multi-domain] Cd Length: 162 Bit Score: 40.04 E-value: 3.70e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 580041203 180 LSGGQQQRVCIARCLAIEPE----VILMDEPTSALDPISTLRVEELVQE-LKEKYTIIMVTHNMQQAAR 243
Cdd:cd03227 78 LSGGEKELSALALILALASLkprpLYILDEIDRGLDPRDGQALAEAILEhLVKGAQVIVITHLPELAEL 146
|
|
| AAA_21 |
pfam13304 |
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being ... |
141-237 |
4.29e-04 |
|
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.
Pssm-ID: 433102 [Multi-domain] Cd Length: 303 Bit Score: 41.22 E-value: 4.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 141 PKIHGIKNKKVLDEIVEKSLRGAAIWDELKDRLHTNAYSLSGGQQQRVCIA---RCLAIEPEVILMDEPTSALDPistLR 217
Cdd:pfam13304 198 NLSDLGEGIEKSLLVDDRLRERGLILLENGGGGELPAFELSDGTKRLLALLaalLSALPKGGLLLIDEPESGLHP---KL 274
|
90 100
....*....|....*....|....
gi 580041203 218 VEELVQELKEKYT----IIMVTHN 237
Cdd:pfam13304 275 LRRLLELLKELSRngaqLILTTHS 298
|
|
| PLN03140 |
PLN03140 |
ABC transporter G family member; Provisional |
64-211 |
8.08e-04 |
|
ABC transporter G family member; Provisional
Pssm-ID: 215599 [Multi-domain] Cd Length: 1470 Bit Score: 40.98 E-value: 8.08e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 64 ITAIIGPSGCGKSTyiktlnrMVELVPSVKTAGkilYRDQDIFDQKYSKEQ---LRTNvGMVFQQPNPFPKS------IY 134
Cdd:PLN03140 908 LTALMGVSGAGKTT-------LMDVLAGRKTGG---YIEGDIRISGFPKKQetfARIS-GYCEQNDIHSPQVtvreslIY 976
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 135 DNITYGPKIHGIKNKKV-LDEIVEkslrgAAIWDELKDRL--HTNAYSLSGGQQQRVCIARCLAIEPEVILMDEPTSALD 211
Cdd:PLN03140 977 SAFLRLPKEVSKEEKMMfVDEVME-----LVELDNLKDAIvgLPGVTGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLD 1051
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
187-236 |
1.34e-03 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 39.88 E-value: 1.34e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 580041203 187 RVCIARCLAIEPEVILMDEPTSALDpISTLRveELVQELKE-KYTIIMVTH 236
Cdd:PRK15064 163 RVLLAQALFSNPDILLLDEPTNNLD-INTIR--WLEDVLNErNSTMIIISH 210
|
|
| UvrA |
COG0178 |
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair]; |
50-77 |
1.89e-03 |
|
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];
Pssm-ID: 439948 [Multi-domain] Cd Length: 941 Bit Score: 39.62 E-value: 1.89e-03
10 20
....*....|....*....|....*...
gi 580041203 50 HALQNINLDIYENQITAIIGPSGCGKST 77
Cdd:COG0178 14 HNLKNIDVDIPRNKLVVITGLSGSGKSS 41
|
|
| rad24 |
TIGR00602 |
checkpoint protein rad24; All proteins in this family for which functions are known are ... |
51-93 |
2.45e-03 |
|
checkpoint protein rad24; All proteins in this family for which functions are known are involved in DNA damage tolerance (likely cell cycle checkpoints).This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129690 [Multi-domain] Cd Length: 637 Bit Score: 39.17 E-value: 2.45e-03
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 580041203 51 ALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRmvELVPSVK 93
Cdd:TIGR00602 99 WLKAQVLENAPKRILLITGPSGCGKSTTIKILSK--ELGIQVQ 139
|
|
| PRK10522 |
PRK10522 |
multidrug transporter membrane component/ATP-binding component; Provisional |
40-236 |
2.59e-03 |
|
multidrug transporter membrane component/ATP-binding component; Provisional
Pssm-ID: 236707 [Multi-domain] Cd Length: 547 Bit Score: 39.18 E-value: 2.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 40 QNLDLWYGENH-ALQNINLDIYENQITAIIGPSGCGKSTYIKTLNRMVElvPSvktAGKILYRDQDIFDQKysKEQLRTN 118
Cdd:PRK10522 326 RNVTFAYQDNGfSVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQ--PQ---SGEILLDGKPVTAEQ--PEDYRKL 398
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 119 VGMVFQQPNPFPKSIydnitygpkihGIKNKKVLDEIVEKSLRGAAIWD--ELKDRLHTNAySLSGGQQQRVCIARCLAI 196
Cdd:PRK10522 399 FSAVFTDFHLFDQLL-----------GPEGKPANPALVEKWLERLKMAHklELEDGRISNL-KLSKGQKKRLALLLALAE 466
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 580041203 197 EPEVILMDEPTSALDPisTLRVE---ELVQELKEK-YTIIMVTH 236
Cdd:PRK10522 467 ERDILLLDEWAADQDP--HFRREfyqVLLPLLQEMgKTIFAISH 508
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
180-241 |
2.59e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 39.27 E-value: 2.59e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 580041203 180 LSGGQQQRVCIARCLAI-----EPEVILmDEPTSALDPISTLRVEELVQELKEKYTIIMVTHN---MQQA 241
Cdd:TIGR02168 1090 LSGGEKALTALALLFAIfkvkpAPFCIL-DEVDAPLDDANVERFANLLKEFSKNTQFIVITHNkgtMEVA 1158
|
|
| uvra |
TIGR00630 |
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ... |
50-91 |
3.94e-03 |
|
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 38.46 E-value: 3.94e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 580041203 50 HALQNINLDIYENQITAIIGPSGCGKST------YIKTLNRMVELVPS 91
Cdd:TIGR00630 10 HNLKNIDVEIPRDKLVVITGLSGSGKSSlafdtiYAEGQRRYVESLSA 57
|
|
| uvrA |
PRK00349 |
excinuclease ABC subunit UvrA; |
50-77 |
7.50e-03 |
|
excinuclease ABC subunit UvrA;
Pssm-ID: 234734 [Multi-domain] Cd Length: 943 Bit Score: 37.74 E-value: 7.50e-03
10 20
....*....|....*....|....*...
gi 580041203 50 HALQNINLDIYENQITAIIGPSGCGKST 77
Cdd:PRK00349 14 HNLKNIDLDIPRDKLVVFTGLSGSGKSS 41
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