|
Name |
Accession |
Description |
Interval |
E-value |
| secA2 |
TIGR03714 |
accessory Sec system translocase SecA2; Members of this protein family are homologous to SecA ... |
9-771 |
0e+00 |
|
accessory Sec system translocase SecA2; Members of this protein family are homologous to SecA and part of the accessory Sec system. This system, including both five core proteins for export and a variable number of proteins for glycosylation, operates in certain Gram-positive pathogens for the maturation and delivery of serine-rich glycoproteins such as the cell surface glycoprotein GspB in Streptococcus gordonii. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 163426 [Multi-domain] Cd Length: 762 Bit Score: 1344.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 9 INELRLKSIRKIVKRINTWSDEVKSYSDDALKQKTIEFKERLASGVdTLDTLLPEAYAVAREASWRVLGMYPKEVQLIGA 88
Cdd:TIGR03714 1 INNLRLKKLRKILNKINALKGKMATLSDEELQAKTAEFKNRLVEGE-SLDDILPEAYAVVREADKRVLGMFPYDVQVLGA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 89 IVLHEGNIAEMQTGEGKTLTATMPLYLNALSGKGTYLITTNDYLAKRDFEEMQPLYEWLGLTASLGFVDIVDYEYQKGEK 168
Cdd:TIGR03714 80 IVLHQGNIAEMKTGEGKTLTATMPLYLNALTGKGAMLVTTNDYLAKRDAEEMGPVYEWLGLTVSLGVVDDPDEEYDANEK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 169 RNIYEHDIIYTTNGRLGFDYLIDNLADSAEGKFLPQLNYGIIDEVDSIILDAAQTPLVISGAPRLQSNLFHIVKEFVDTL 248
Cdd:TIGR03714 160 RKIYNSDIVYTTNSALGFDYLIDNLASNKEGKFLRPFNYVIVDEVDSVLLDSAQTPLVISGAPRVQSNLYHIADTFVRTL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 249 IEDVHFKMKKTKKEIWLLNQGIEAAQSYFNVEDLYSEQAMVLVRNINLALRAQYLFESNVDYFVYNGDIVLIDRITGRML 328
Cdd:TIGR03714 240 KEDVDYIFKKDKKEVWLTDKGIEKAEQYFKIDNLYSEEYFELVRHINLALRAHYLFKRNKDYVVTNGEVVLLDRITGRLL 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 329 PGTKLQAGLHQAIEAKEGMEVSTDKSVMATITFQNLFKLFESFSGMTATGKLGESEFFDLYSKIVVQAPTDKAIQRIDEP 408
Cdd:TIGR03714 320 EGTKLQSGIHQAIEAKEHVELSKETRAMASITYQNLFKMFNKLSGMTGTGKVAEKEFIETYSLSVVKIPTNKPIIRIDYP 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 409 DKVFRSVDEKNIAMIHDIVELHETGRPVLLITRTAEAAEYFSKVLFQMDIPNNLLIAQNVAKEAQMIAEAGQIGSMTVAT 488
Cdd:TIGR03714 400 DKIYATLPEKLMATLEDVKEYHETGQPVLLITGSVEMSEIYSELLLREGIPHNLLNAQNAAKEAQIIAEAGQKGAVTVAT 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 489 SMAGRGTDIKLGEGVEALGGLAVIIHEHMENSRVDRQLRGRSGRQGDPGSSCIYISLDDYLVKRWSDSNLAENNQLYSLD 568
Cdd:TIGR03714 480 SMAGRGTDIKLGKGVAELGGLAVIGTERMENSRVDLQLRGRSGRQGDPGSSQFFVSLEDDLIKRWSPSWLKKYYKKYSVK 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 569 AQRLSQSNLFNRKVKQIVVKAQRISEEQGVKAREMANEFEKSISIQRDLVYEERNRVLEIDDAENRDFKALAKDVFEMFV 648
Cdd:TIGR03714 560 DSKLKPSALFKRRFRKIVEKAQRASEDKGESAREQTNEFEESLSIQRENIYAERNRLIEGSDFLDDDVDQIIDDVFNMYA 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 649 NEEKVLTKSRVVEYIYQNLSFQFNKDVACVNFKDKQAAVTFLLEQFEKQLALNRKNMQSAYYYNIFVQKVFLKAIDSCWL 728
Cdd:TIGR03714 640 EEQDLSNKSLLKRFILENLSYQFKNDPDEFDLKNKEAIKDFLKEIADKELSEKKKVLNNDYLFNDFERLSILKAIDENWI 719
|
730 740 750 760
....*....|....*....|....*....|....*....|...
gi 582840389 729 EQVDYLQQLKASVNQRQNGQRNAIFEYHRVALDSFEVMTRNIK 771
Cdd:TIGR03714 720 EQVDYLQQLKTVVTNRQNGQRNPIFEYHKEALESYEYMKKEIK 762
|
|
| PRK09200 |
PRK09200 |
preprotein translocase subunit SecA; Reviewed |
1-796 |
0e+00 |
|
preprotein translocase subunit SecA; Reviewed
Pssm-ID: 236408 [Multi-domain] Cd Length: 790 Bit Score: 1274.10 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 1 MKHKLDVTINELRLKSIRKIVKRINTWSDEVKSYSDDALKQKTIEFKERLASGvDTLDTLLPEAYAVAREASWRVLGMYP 80
Cdd:PRK09200 1 MKKKLLGDIDKRRLKKYRKIVKQINKLEGKMSSLSDEELRQKTIEFKERLASG-KTLDDILPEAFAVVREAAKRVLGMRP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 81 KEVQLIGAIVLHEGNIAEMQTGEGKTLTATMPLYLNALSGKGTYLITTNDYLAKRDFEEMQPLYEWLGLTASLGFVDIVD 160
Cdd:PRK09200 80 YDVQLIGALVLHEGNIAEMQTGEGKTLTATMPLYLNALEGKGVHLITVNDYLAKRDAEEMGQVYEFLGLTVGLNFSDIDD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 161 yeyqKGEKRNIYEHDIIYTTNGRLGFDYLIDNLADSAEGKFLPQLNYGIIDEVDSIILDAAQTPLVISGAPRLQSNLFHI 240
Cdd:PRK09200 160 ----ASEKKAIYEADIIYTTNSELGFDYLRDNLADSKEDKVQRPLNYAIIDEIDSILLDEAQTPLIISGKPRVQSNLYHI 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 241 VKEFVDTLIEDVHFKMKKTKKEIWLLNQGIEAAQSYFNVEDLYSEQAMVLVRNINLALRAQYLFESNVDYFVYNGDIVLI 320
Cdd:PRK09200 236 AAKFVKTLEEDVDYEFDEEKKEVWLTDQGIEKAESYFGIDNLYSLEHQVLYRHIILALRAHVLFKRDVDYIVYDGEIVLV 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 321 DRITGRMLPGTKLQAGLHQAIEAKEGMEVSTDKSVMATITFQNLFKLFESFSGMTATGKLGESEFFDLYSKIVVQAPTDK 400
Cdd:PRK09200 316 DRFTGRVLPGRKLQDGLHQAIEAKEGVEITEENRTMASITIQNLFRMFPKLSGMTGTAKTEEKEFFEVYNMEVVQIPTNR 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 401 AIQRIDEPDKVFRSVDEKNIAMIHDIVELHETGRPVLLITRTAEAAEYFSKVLFQMDIPNNLLIAQNVAKEAQMIAEAGQ 480
Cdd:PRK09200 396 PIIRIDYPDKVFVTLDEKYKAVIEEVKERHETGRPVLIGTGSIEQSETFSKLLDEAGIPHNLLNAKNAAKEAQIIAEAGQ 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 481 IGSMTVATSMAGRGTDIKLGEGVEALGGLAVIIHEHMENSRVDRQLRGRSGRQGDPGSSCIYISLDDYLVKRWSDSNLAE 560
Cdd:PRK09200 476 KGAVTVATNMAGRGTDIKLGEGVHELGGLAVIGTERMESRRVDLQLRGRSGRQGDPGSSQFFISLEDDLLKRFAPEELEK 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 561 NNQLYSLDAQRLsQSNLFNRKVKQIVVKAQRISEEQGVKAREMANEFEKSISIQRDLVYEERNRVLEIDDAENRDFKALA 640
Cdd:PRK09200 556 LKKKLKTDAQRL-TGLLFNRKVHKIVVKAQRISEGAGYSAREYALELDDVINIQRDVVYKERNRLLEEDDRDLIDIVILM 634
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 641 KDVFEMFVNEEKVLTKSRVVEYIYQNLSFQFNKDVACVNFKDKQAAVTFLLEQFEKQLALNRKNMQSAYYYNIFVQKVFL 720
Cdd:PRK09200 635 IDVYLEAVAEEYLLEKSLLEEWIYENLSFQLNEILSNTNFPDKKEVVQFLLEEAEKQLKEKRNKLPSATLYNQFLRKVAL 714
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 582840389 721 KAIDSCWLEQVDYLQQLKASVNQRQNGQRNAIFEYHRVALDSFEVMTRNIKKRMVKNICQSMITFDKEGMPVIHFP 796
Cdd:PRK09200 715 KAIDQNWVEQVDALQQLKEGIGLRQYGQRNPIREYQKEALESFEYMYENIKKDMVRNLLLSLLVFDKEGEIVIHFP 790
|
|
| SecA |
COG0653 |
Preprotein translocase subunit SecA (ATPase, RNA helicase) [Intracellular trafficking, ... |
10-778 |
0e+00 |
|
Preprotein translocase subunit SecA (ATPase, RNA helicase) [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440418 [Multi-domain] Cd Length: 876 Bit Score: 680.60 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 10 NELRLKSIRKIVKRINTWSDEVKSYSDDALKQKTIEFKERLASGvDTLDTLLPEAYAVAREASWRVLGMYPKEVQLIGAI 89
Cdd:COG0653 13 NDRELKRLRKIVDKINALEPEMEALSDEELRAKTDEFKERLANG-ETLDDLLPEAFAVVREASKRVLGMRHFDVQLIGGI 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 90 VLHEGNIAEMQTGEGKTLTATMPLYLNALSGKGTYLITTNDYLAKRDFEEMQPLYEWLGLTaslgfVDIVDYEYQKGEKR 169
Cdd:COG0653 92 VLHQGKIAEMKTGEGKTLVATLPAYLNALTGKGVHVVTVNDYLAKRDAEWMGRLYRFLGLS-----VGVIVHGMDPEERR 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 170 NIYEHDIIYTTNGRLGFDYLIDNLADSAEGKFLPQLNYGIIDEVDSIILDAAQTPLVISGAPRLQSNLFHIVKEFVDTLI 249
Cdd:COG0653 167 AAYAADITYGTNNEFGFDYLRDNMVFSLEDMVQRGLNYAIVDEVDSILIDEARTPLIISGPAEDSTDLYYRINKLVPRLK 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 250 EDVHFKMKKTKKEIWLLNQGIEAAQSYFNVEDLYSEQAMVLVRNINLALRAQYLFESNVDYFVYNGDIVLIDRITGRMLP 329
Cdd:COG0653 247 RDGDYTVDEKARTVTLTEEGIEKVEKLLGIDNLYDPENIELVHHLNQALRAHALFKRDVDYIVKDGEVVIVDEFTGRLMP 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 330 GTKLQAGLHQAIEAKEGMEVSTDKSVMATITFQNLFKLFESFSGMTATGKLGESEFFDLYSKIVVQAPTDKAIQRIDEPD 409
Cdd:COG0653 327 GRRYSDGLHQAIEAKEGVKIQNENQTLASITFQNYFRMYEKLAGMTGTADTEAEEFREIYGLDVVVIPTNRPMIRKDEPD 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 410 KVFRSVDEKNIAMIHDIVELHETGRPVLLITRTAEAAEYFSKVLFQMDIPNNLLIAQNVAKEAQMIAEAGQIGSMTVATS 489
Cdd:COG0653 407 LVYKTEEEKFNAVVEDIKERHEKGQPVLVGTTSIEKSELLSKLLKKEGIPHNVLNAKQHEREAEIVAQAGRPGAVTIATN 486
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 490 MAGRGTDIKLG---------------------------------EGVEALGGLAVIIHEHMENSRVDRQLRGRSGRQGDP 536
Cdd:COG0653 487 MAGRGTDIVLGgnpeflaaaeladrgleweeaiakikaewqaehEEVLEAGGLHVIGTERHESRRIDNQLRGRSGRQGDP 566
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 537 GSSCIYISLDDYLVKRW-SDsnlaennqlySLDA--QRLS-------QSNLFNRKVKqivvKAQRiseeqGVKAR--EM- 603
Cdd:COG0653 567 GSSRFYLSLEDDLMRIFgSD----------RIKGmmDKLGmeegepiEHKMVSKAIE----NAQK-----KVEGRnfDIr 627
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 604 ---------ANEfeksisiQRDLVYEERNRVLEIDD--------------------------AENRDFKALAKDVFEMF- 647
Cdd:COG0653 628 knlleyddvMND-------QRKVIYEQRREILEGEDlsetildmredviedlvdeyipegsyPEQWDLEGLEEALKELFg 700
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 648 -------VNEEKVLTKSRVVEYIYqnlsfqfnkDVACVNFKDKQAAVTF-LLEQFEKQlalnrknmqsayyynifvqkVF 719
Cdd:COG0653 701 ldlpieeWLDEEGLDEEELRERLL---------EAADEAYEEKEEELGPeVMRELERV--------------------VL 751
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....*....
gi 582840389 720 LKAIDSCWLEQVDYLQQLKASVNQRQNGQRNAIFEYHRVALDSFEVMTRNIKKRMVKNI 778
Cdd:COG0653 752 LQVLDRKWREHLDAMDHLRQGIGLRGYAQKDPLVEYKREAFELFEEMLDSIKEEVVRYL 810
|
|
| SecA_DEAD |
smart00957 |
SecA DEAD-like domain; SecA protein binds to the plasma membrane where it interacts with ... |
3-386 |
0e+00 |
|
SecA DEAD-like domain; SecA protein binds to the plasma membrane where it interacts with proOmpA to support translocation of proOmpA through the membrane. SecA protein achieves this translocation, in association with SecY protein, in an ATP dependent manner. This domain represents the N-terminal ATP-dependent helicase domain, which is related to the.
Pssm-ID: 214937 [Multi-domain] Cd Length: 380 Bit Score: 574.76 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 3 HKLDVTINELRLKSIRKIVKRINTWSDEVKSYSDDALKQKTIEFKERLASGvDTLDTLLPEAYAVAREASWRVLGMYPKE 82
Cdd:smart00957 2 KKLFGSKNDRELKRLRKIVDQINALEPEMEALSDEELRAKTAEFKERLAEG-ESLDDLLPEAFAVVREAAKRVLGMRHFD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 83 VQLIGAIVLHEGNIAEMQTGEGKTLTATMPLYLNALSGKGTYLITTNDYLAKRDFEEMQPLYEWLGLTaslgfVDIVDYE 162
Cdd:smart00957 81 VQLIGGIVLHEGKIAEMKTGEGKTLVATLPAYLNALTGKGVHVVTVNDYLAKRDAEWMGPLYEFLGLT-----VGVIVSG 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 163 YQKGEKRNIYEHDIIYTTNGRLGFDYLIDNLADSAEGKFLPQLNYGIIDEVDSIILDAAQTPLVISG-APRLQSNLFHIV 241
Cdd:smart00957 156 MSPEERRAAYAADITYGTNNEFGFDYLRDNMAFSKEDKVQRGLNYAIVDEVDSILIDEARTPLIISGpAEDESSDLYHRA 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 242 KEFVDTLIEDVHFKMKKTKKEIWLLNQGIEAAQSYFNVEDLYSEQAMVLVRNINLALRAQYLFESNVDYFVYNGDIVLID 321
Cdd:smart00957 236 DKFVPRLKEDEDYTVDEKSRTVELTEEGIEKAEKLLGIDNLYDPENIELLHHVNQALRAHYLFKRDVDYIVRDGEVVIVD 315
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 582840389 322 RITGRMLPGTKLQAGLHQAIEAKEGMEVSTDKSVMATITFQNLFKLFESFSGMTATGKLGESEFF 386
Cdd:smart00957 316 EFTGRVMEGRRYSDGLHQAIEAKEGVEIQEENQTLATITFQNYFRMYKKLSGMTGTAKTEAEEFR 380
|
|
| SecA_DEAD |
pfam07517 |
SecA DEAD-like domain; SecA protein binds to the plasma membrane where it interacts with ... |
1-385 |
0e+00 |
|
SecA DEAD-like domain; SecA protein binds to the plasma membrane where it interacts with proOmpA to support translocation of proOmpA through the membrane. SecA protein achieves this translocation, in association with SecY protein, in an ATP dependent manner. This domain represents the N-terminal ATP-dependent helicase domain, which is related to the pfam00270.
Pssm-ID: 462190 [Multi-domain] Cd Length: 379 Bit Score: 553.26 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 1 MKHKLDvTINELRLKSIRKIVKRINTWSDEVKSYSDDALKQKTIEFKERLASGvDTLDTLLPEAYAVAREASWRVLGMYP 80
Cdd:pfam07517 1 LKKIFG-SPNERDLKRLRKIVDQINALEEELKALSDEELRAKTDELRERLREG-ESLDDILPEAFALVREAAKRVLGMRH 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 81 KEVQLIGAIVLHEGNIAEMQTGEGKTLTATMPLYLNALSGKGTYLITTNDYLAKRDFEEMQPLYEWLGLTaslgfVDIVD 160
Cdd:pfam07517 79 YDVQLIGGLVLHEGKIAEMKTGEGKTLTATLPAYLNALSGKGVHVVTVNDYLAKRDAEWMGPLYEFLGLT-----VGVIT 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 161 YEYQKGEKRNIYEHDIIYTTNGRLGFDYLIDNLADSAEGKFLPQLNYGIIDEVDSIILDAAQTPLVISGAPRLQSNLFHI 240
Cdd:pfam07517 154 SDMDPEERRAAYNADITYGTNNELGFDYLRDNMATSKEDKVQRGLNFAIVDEVDSILIDEARTPLIISGPSEDDSELYRE 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 241 VKEFVDTLIEDVHFKMKKTKKEIWLLNQGIEAAQSYFNVEDLYSEQAMVLVRNINLALRAQYLFESNVDYFVYNGDIVLI 320
Cdd:pfam07517 234 ADRLVKSLEEDGDYEIDEKSKNVELTEKGIEKIEKLLGIDNLYDPENVELLHHINQALKAHHLFKRDVDYIVRDGEVVIV 313
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 582840389 321 DRITGRMLPGTKLQAGLHQAIEAKEGMEVSTDKSVMATITFQNLFKLFESFSGMTATGKLGESEF 385
Cdd:pfam07517 314 DEFTGRVMPGRRWSDGLHQAIEAKEGVEITPESQTLASITYQNFFRLYPKLSGMTGTAKTEAEEF 378
|
|
| DEXDc_SecA |
cd17928 |
DEXD-box helicase domain of SecA; SecA is a part of the Sec translocase that transports the ... |
38-398 |
2.72e-93 |
|
DEXD-box helicase domain of SecA; SecA is a part of the Sec translocase that transports the vast majority of bacterial and ER-exported proteins. SecA binds both the signal sequence and the mature domain of the preprotein emerging from the ribosome. SecA belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350686 [Multi-domain] Cd Length: 230 Bit Score: 291.36 E-value: 2.72e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 38 ALKQKTIEFKERLASGvDTLDTLLPEAYAVAREASWRVLGMYPKEVQLIGAIVLHEGNIAEMQTGEGKTLTATMPLYLNA 117
Cdd:cd17928 1 ELRAKTDELRERLAKG-ETLDDLLPEAFALVREAARRVLGMRPFDVQLIGGLVLHEGKIAEMKTGEGKTLTATLPAYLNA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 118 LSGKGTYLITTNDYLAKRDFEEMQPLYEWLGLTaslgfVDIVDYEYQKGEKRNIYEHDIIYTTNGRLGFDYLIDNLADSA 197
Cdd:cd17928 80 LTGKGVHVVTVNDYLARRDAEWMGPLYEFLGLT-----VGVILSDMSPDERREAYAADITYGTNNELGFDYLRDNMVTSK 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 198 EGKFLPQLNYGIIDEVDSIILDAAQTPLVISGaprlqsnlfhivkefvdtliedvhfkmkktkkeiwllnqgieaaqsyf 277
Cdd:cd17928 155 EDLVQRGLNFAIVDEVDSILIDEARTPLIISG------------------------------------------------ 186
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 278 nvedlyseqamvlvrninlalraqylfesnvdyfvyngdivlidritgrmlpgtklqaglhqaieakegmevstdksVMA 357
Cdd:cd17928 187 -----------------------------------------------------------------------------TLA 189
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 582840389 358 TITFQNLFKLFESFSGMTATGKLGESEFFDLYSKIVVQAPT 398
Cdd:cd17928 190 TITFQNYFRLYPKLAGMTGTAKTEAEEFREIYNLDVVVIPT 230
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| secA2 |
TIGR03714 |
accessory Sec system translocase SecA2; Members of this protein family are homologous to SecA ... |
9-771 |
0e+00 |
|
accessory Sec system translocase SecA2; Members of this protein family are homologous to SecA and part of the accessory Sec system. This system, including both five core proteins for export and a variable number of proteins for glycosylation, operates in certain Gram-positive pathogens for the maturation and delivery of serine-rich glycoproteins such as the cell surface glycoprotein GspB in Streptococcus gordonii. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 163426 [Multi-domain] Cd Length: 762 Bit Score: 1344.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 9 INELRLKSIRKIVKRINTWSDEVKSYSDDALKQKTIEFKERLASGVdTLDTLLPEAYAVAREASWRVLGMYPKEVQLIGA 88
Cdd:TIGR03714 1 INNLRLKKLRKILNKINALKGKMATLSDEELQAKTAEFKNRLVEGE-SLDDILPEAYAVVREADKRVLGMFPYDVQVLGA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 89 IVLHEGNIAEMQTGEGKTLTATMPLYLNALSGKGTYLITTNDYLAKRDFEEMQPLYEWLGLTASLGFVDIVDYEYQKGEK 168
Cdd:TIGR03714 80 IVLHQGNIAEMKTGEGKTLTATMPLYLNALTGKGAMLVTTNDYLAKRDAEEMGPVYEWLGLTVSLGVVDDPDEEYDANEK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 169 RNIYEHDIIYTTNGRLGFDYLIDNLADSAEGKFLPQLNYGIIDEVDSIILDAAQTPLVISGAPRLQSNLFHIVKEFVDTL 248
Cdd:TIGR03714 160 RKIYNSDIVYTTNSALGFDYLIDNLASNKEGKFLRPFNYVIVDEVDSVLLDSAQTPLVISGAPRVQSNLYHIADTFVRTL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 249 IEDVHFKMKKTKKEIWLLNQGIEAAQSYFNVEDLYSEQAMVLVRNINLALRAQYLFESNVDYFVYNGDIVLIDRITGRML 328
Cdd:TIGR03714 240 KEDVDYIFKKDKKEVWLTDKGIEKAEQYFKIDNLYSEEYFELVRHINLALRAHYLFKRNKDYVVTNGEVVLLDRITGRLL 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 329 PGTKLQAGLHQAIEAKEGMEVSTDKSVMATITFQNLFKLFESFSGMTATGKLGESEFFDLYSKIVVQAPTDKAIQRIDEP 408
Cdd:TIGR03714 320 EGTKLQSGIHQAIEAKEHVELSKETRAMASITYQNLFKMFNKLSGMTGTGKVAEKEFIETYSLSVVKIPTNKPIIRIDYP 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 409 DKVFRSVDEKNIAMIHDIVELHETGRPVLLITRTAEAAEYFSKVLFQMDIPNNLLIAQNVAKEAQMIAEAGQIGSMTVAT 488
Cdd:TIGR03714 400 DKIYATLPEKLMATLEDVKEYHETGQPVLLITGSVEMSEIYSELLLREGIPHNLLNAQNAAKEAQIIAEAGQKGAVTVAT 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 489 SMAGRGTDIKLGEGVEALGGLAVIIHEHMENSRVDRQLRGRSGRQGDPGSSCIYISLDDYLVKRWSDSNLAENNQLYSLD 568
Cdd:TIGR03714 480 SMAGRGTDIKLGKGVAELGGLAVIGTERMENSRVDLQLRGRSGRQGDPGSSQFFVSLEDDLIKRWSPSWLKKYYKKYSVK 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 569 AQRLSQSNLFNRKVKQIVVKAQRISEEQGVKAREMANEFEKSISIQRDLVYEERNRVLEIDDAENRDFKALAKDVFEMFV 648
Cdd:TIGR03714 560 DSKLKPSALFKRRFRKIVEKAQRASEDKGESAREQTNEFEESLSIQRENIYAERNRLIEGSDFLDDDVDQIIDDVFNMYA 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 649 NEEKVLTKSRVVEYIYQNLSFQFNKDVACVNFKDKQAAVTFLLEQFEKQLALNRKNMQSAYYYNIFVQKVFLKAIDSCWL 728
Cdd:TIGR03714 640 EEQDLSNKSLLKRFILENLSYQFKNDPDEFDLKNKEAIKDFLKEIADKELSEKKKVLNNDYLFNDFERLSILKAIDENWI 719
|
730 740 750 760
....*....|....*....|....*....|....*....|...
gi 582840389 729 EQVDYLQQLKASVNQRQNGQRNAIFEYHRVALDSFEVMTRNIK 771
Cdd:TIGR03714 720 EQVDYLQQLKTVVTNRQNGQRNPIFEYHKEALESYEYMKKEIK 762
|
|
| PRK09200 |
PRK09200 |
preprotein translocase subunit SecA; Reviewed |
1-796 |
0e+00 |
|
preprotein translocase subunit SecA; Reviewed
Pssm-ID: 236408 [Multi-domain] Cd Length: 790 Bit Score: 1274.10 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 1 MKHKLDVTINELRLKSIRKIVKRINTWSDEVKSYSDDALKQKTIEFKERLASGvDTLDTLLPEAYAVAREASWRVLGMYP 80
Cdd:PRK09200 1 MKKKLLGDIDKRRLKKYRKIVKQINKLEGKMSSLSDEELRQKTIEFKERLASG-KTLDDILPEAFAVVREAAKRVLGMRP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 81 KEVQLIGAIVLHEGNIAEMQTGEGKTLTATMPLYLNALSGKGTYLITTNDYLAKRDFEEMQPLYEWLGLTASLGFVDIVD 160
Cdd:PRK09200 80 YDVQLIGALVLHEGNIAEMQTGEGKTLTATMPLYLNALEGKGVHLITVNDYLAKRDAEEMGQVYEFLGLTVGLNFSDIDD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 161 yeyqKGEKRNIYEHDIIYTTNGRLGFDYLIDNLADSAEGKFLPQLNYGIIDEVDSIILDAAQTPLVISGAPRLQSNLFHI 240
Cdd:PRK09200 160 ----ASEKKAIYEADIIYTTNSELGFDYLRDNLADSKEDKVQRPLNYAIIDEIDSILLDEAQTPLIISGKPRVQSNLYHI 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 241 VKEFVDTLIEDVHFKMKKTKKEIWLLNQGIEAAQSYFNVEDLYSEQAMVLVRNINLALRAQYLFESNVDYFVYNGDIVLI 320
Cdd:PRK09200 236 AAKFVKTLEEDVDYEFDEEKKEVWLTDQGIEKAESYFGIDNLYSLEHQVLYRHIILALRAHVLFKRDVDYIVYDGEIVLV 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 321 DRITGRMLPGTKLQAGLHQAIEAKEGMEVSTDKSVMATITFQNLFKLFESFSGMTATGKLGESEFFDLYSKIVVQAPTDK 400
Cdd:PRK09200 316 DRFTGRVLPGRKLQDGLHQAIEAKEGVEITEENRTMASITIQNLFRMFPKLSGMTGTAKTEEKEFFEVYNMEVVQIPTNR 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 401 AIQRIDEPDKVFRSVDEKNIAMIHDIVELHETGRPVLLITRTAEAAEYFSKVLFQMDIPNNLLIAQNVAKEAQMIAEAGQ 480
Cdd:PRK09200 396 PIIRIDYPDKVFVTLDEKYKAVIEEVKERHETGRPVLIGTGSIEQSETFSKLLDEAGIPHNLLNAKNAAKEAQIIAEAGQ 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 481 IGSMTVATSMAGRGTDIKLGEGVEALGGLAVIIHEHMENSRVDRQLRGRSGRQGDPGSSCIYISLDDYLVKRWSDSNLAE 560
Cdd:PRK09200 476 KGAVTVATNMAGRGTDIKLGEGVHELGGLAVIGTERMESRRVDLQLRGRSGRQGDPGSSQFFISLEDDLLKRFAPEELEK 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 561 NNQLYSLDAQRLsQSNLFNRKVKQIVVKAQRISEEQGVKAREMANEFEKSISIQRDLVYEERNRVLEIDDAENRDFKALA 640
Cdd:PRK09200 556 LKKKLKTDAQRL-TGLLFNRKVHKIVVKAQRISEGAGYSAREYALELDDVINIQRDVVYKERNRLLEEDDRDLIDIVILM 634
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 641 KDVFEMFVNEEKVLTKSRVVEYIYQNLSFQFNKDVACVNFKDKQAAVTFLLEQFEKQLALNRKNMQSAYYYNIFVQKVFL 720
Cdd:PRK09200 635 IDVYLEAVAEEYLLEKSLLEEWIYENLSFQLNEILSNTNFPDKKEVVQFLLEEAEKQLKEKRNKLPSATLYNQFLRKVAL 714
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 582840389 721 KAIDSCWLEQVDYLQQLKASVNQRQNGQRNAIFEYHRVALDSFEVMTRNIKKRMVKNICQSMITFDKEGMPVIHFP 796
Cdd:PRK09200 715 KAIDQNWVEQVDALQQLKEGIGLRQYGQRNPIREYQKEALESFEYMYENIKKDMVRNLLLSLLVFDKEGEIVIHFP 790
|
|
| secA |
PRK12906 |
preprotein translocase subunit SecA; Reviewed |
10-771 |
0e+00 |
|
preprotein translocase subunit SecA; Reviewed
Pssm-ID: 237260 [Multi-domain] Cd Length: 796 Bit Score: 699.54 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 10 NELRLKSIRKIVKRINTWSDEVKSYSDDALKQKTIEFKERLASGvDTLDTLLPEAYAVAREASWRVLGMYPKEVQLIGAI 89
Cdd:PRK12906 12 DKRELKRLEKIADKVNALEDEYEKLSDEQLQAKTPEFRDRIKDG-ESLDDLLPEAFAVAREGAKRVLGLRPFDVQIIGGI 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 90 VLHEGNIAEMQTGEGKTLTATMPLYLNALSGKGTYLITTNDYLAKRDFEEMQPLYEWLGLTaslgfVDIVDYEYQKGEKR 169
Cdd:PRK12906 91 VLHEGNIAEMKTGEGKTLTATLPVYLNALTGKGVHVVTVNEYLSSRDATEMGELYRWLGLT-----VGLNLNSMSPDEKR 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 170 NIYEHDIIYTTNGRLGFDYLIDNLADSAEGKFLPQLNYGIIDEVDSIILDAAQTPLVISGAPRLQSNLFHIVKEFVDTLI 249
Cdd:PRK12906 166 AAYNCDITYSTNSELGFDYLRDNMVVYKEQMVQRPLNYAIVDEVDSILIDEARTPLIISGQAEKATDLYIRADRFVKTLI 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 250 ED-----------VHFKMKKTKKEIWLLNQGIEAAQSYFNVEDLYSEQAMVLVRNINLALRAQYLFESNVDYFVYNGDIV 318
Cdd:PRK12906 246 KDeaedgdddedtGDYKIDEKTKTISLTEQGIRKAEKLFGLDNLYDSENTALAHHIDQALRANYIMLKDIDYVVQDGEVL 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 319 LIDRITGRMLPGTKLQAGLHQAIEAKEGMEVSTDKSVMATITFQNLFKLFESFSGMTATGKLGESEFFDLYSKIVVQAPT 398
Cdd:PRK12906 326 IVDEFTGRVMEGRRYSDGLHQAIEAKEGVKIQEENQTLATITYQNFFRMYKKLSGMTGTAKTEEEEFREIYNMEVITIPT 405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 399 DKAIQRIDEPDKVFRSVDEKNIAMIHDIVELHETGRPVLLITRTAEAAEYFSKVLFQMDIPNNLLIAQNVAKEAQMIAEA 478
Cdd:PRK12906 406 NRPVIRKDSPDLLYPTLDSKFNAVVKEIKERHAKGQPVLVGTVAIESSERLSHLLDEAGIPHAVLNAKNHAKEAEIIMNA 485
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 479 GQIGSMTVATSMAGRGTDIKLGEGVEALGGLAVIIHEHMENSRVDRQLRGRSGRQGDPGSSCIYISLDDYLVKRW-SDSN 557
Cdd:PRK12906 486 GQRGAVTIATNMAGRGTDIKLGPGVKELGGLAVIGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSLEDDLMRRFgSDRV 565
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 558 LAENNQLYSLDAQRLSQSNLFNRKVKqivvKAQRISEEQGVKAREMANEFEKSISIQRDLVYEERNRVLEIDDAENRDFK 637
Cdd:PRK12906 566 KAFLDRLGMNDDDQVIESRMITRQVE----SAQKRVEGNNYDTRKQLLQYDDVMREQREVIYKQRMQVINEDKDLKEVLM 641
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 638 ALAKDVFEMFVNEEKVLTKSR-----VVEYIYQNLSFQFNKDVACVNFKDKQAAVTFLLEQFEKQLALNRKNMQSAYYYN 712
Cdd:PRK12906 642 PMIKRTVDRQVQMYTQGDKKDwdldaLRDFIVSAMPDEETFDFEDLKGKSPEELKKRLLDIVEDNYAEKEKQLGDPTQML 721
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*....
gi 582840389 713 IFVQKVFLKAIDSCWLEQVDYLQQLKASVNQRQNGQRNAIFEYHRVALDSFEVMTRNIK 771
Cdd:PRK12906 722 EFEKVVILRVVDSHWTDHIDAMDQLRQSIGLRGYGQLNPLVEYQEEGYRMFEEMISNID 780
|
|
| PRK12904 |
PRK12904 |
preprotein translocase subunit SecA; Reviewed |
10-778 |
0e+00 |
|
preprotein translocase subunit SecA; Reviewed
Pssm-ID: 237259 [Multi-domain] Cd Length: 830 Bit Score: 697.60 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 10 NELRLKSIRKIVKRINTWSDEVKSYSDDALKQKTIEFKERLASGvDTLDTLLPEAYAVAREASWRVLGMYPKEVQLIGAI 89
Cdd:PRK12904 13 NDRELKRLRKIVDKINALEPEMEKLSDEELKAKTAEFKERLAKG-ETLDDLLPEAFAVVREASKRVLGMRHFDVQLIGGM 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 90 VLHEGNIAEMQTGEGKTLTATMPLYLNALSGKGTYLITTNDYLAKRDFEEMQPLYEWLGLTaslgfVDIVDYEYQKGEKR 169
Cdd:PRK12904 92 VLHEGKIAEMKTGEGKTLVATLPAYLNALTGKGVHVVTVNDYLAKRDAEWMGPLYEFLGLS-----VGVILSGMSPEERR 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 170 NIYEHDIIYTTNGRLGFDYLIDNLADSAEGKFLPQLNYGIIDEVDSIILDAAQTPLVISGAPRLQSNLFHIVKEFVDTLI 249
Cdd:PRK12904 167 EAYAADITYGTNNEFGFDYLRDNMVFSLEERVQRGLNYAIVDEVDSILIDEARTPLIISGPAEDSSELYKRANKIVPTLE 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 250 EDVHFKMKKTKKEIWLLNQGIEAAQSYFNVEDLYSEQAMVLVRNINLALRAQYLFESNVDYFVYNGDIVLIDRITGRMLP 329
Cdd:PRK12904 247 KEGDYTVDEKSRTVGLTEEGIEKAEKLLGIENLYDPENIALVHHLNQALRAHELFKRDVDYIVKDGEVVIVDEFTGRLMP 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 330 GTKLQAGLHQAIEAKEGMEVSTDKSVMATITFQNLFKLFESFSGMTATGKLGESEFFDLYSKIVVQAPTDKAIQRIDEPD 409
Cdd:PRK12904 327 GRRYSDGLHQAIEAKEGVKIQNENQTLASITFQNYFRMYEKLAGMTGTADTEAEEFREIYNLDVVVIPTNRPMIRIDHPD 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 410 KVFRSVDEKNIAMIHDIVELHETGRPVLLITRTAEAAEYFSKVLFQMDIPNNLLIAQNVAKEAQMIAEAGQIGSMTVATS 489
Cdd:PRK12904 407 LIYKTEKEKFDAVVEDIKERHKKGQPVLVGTVSIEKSELLSKLLKKAGIPHNVLNAKNHEREAEIIAQAGRPGAVTIATN 486
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 490 MAGRGTDIKLG------------------------------EGVEALGGLAVIIHEHMENSRVDRQLRGRSGRQGDPGSS 539
Cdd:PRK12904 487 MAGRGTDIKLGgnpemlaaalleeeteeqiakikaewqeehEEVLEAGGLHVIGTERHESRRIDNQLRGRSGRQGDPGSS 566
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 540 CIYISLDDYLVKRW-SDsnlaennqlySLDA--QRLS-------QSNLFNRKVKqivvKAQRISEEQGVKAR-------E 602
Cdd:PRK12904 567 RFYLSLEDDLMRIFgSD----------RVKGmmDRLGmkegeaiEHKMVTRAIE----NAQKKVEGRNFDIRkqlleydD 632
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 603 MANEfeksisiQRDLVYEERNRVLEIDDAENRdFKALAKDVFEMFVNE---EKVLTKSRVVEYIYQNLSFQFNKDVACVN 679
Cdd:PRK12904 633 VMND-------QRKVIYAQRNEILEGEDLSET-ILDMREDVIEDLVDAyipPGSYEEDWDLEGLEEALKTDFGLELPIEE 704
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 680 FKDKQAAVTFLLEQFEKQL--ALNRKNMQ-SAYYYNIFVQKVFLKAIDSCWLEQVDYLQQLKASVNQRQNGQRNAIFEYH 756
Cdd:PRK12904 705 WLEEGLDEEELRERILEAAeeAYEEKEEElGEEQMREFERVVMLQVLDTKWREHLAAMDHLRQGIGLRGYAQKDPLQEYK 784
|
810 820
....*....|....*....|..
gi 582840389 757 RVALDSFEVMTRNIKKRMVKNI 778
Cdd:PRK12904 785 REGFELFEEMLDSIKEEVVRTL 806
|
|
| SecA |
COG0653 |
Preprotein translocase subunit SecA (ATPase, RNA helicase) [Intracellular trafficking, ... |
10-778 |
0e+00 |
|
Preprotein translocase subunit SecA (ATPase, RNA helicase) [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440418 [Multi-domain] Cd Length: 876 Bit Score: 680.60 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 10 NELRLKSIRKIVKRINTWSDEVKSYSDDALKQKTIEFKERLASGvDTLDTLLPEAYAVAREASWRVLGMYPKEVQLIGAI 89
Cdd:COG0653 13 NDRELKRLRKIVDKINALEPEMEALSDEELRAKTDEFKERLANG-ETLDDLLPEAFAVVREASKRVLGMRHFDVQLIGGI 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 90 VLHEGNIAEMQTGEGKTLTATMPLYLNALSGKGTYLITTNDYLAKRDFEEMQPLYEWLGLTaslgfVDIVDYEYQKGEKR 169
Cdd:COG0653 92 VLHQGKIAEMKTGEGKTLVATLPAYLNALTGKGVHVVTVNDYLAKRDAEWMGRLYRFLGLS-----VGVIVHGMDPEERR 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 170 NIYEHDIIYTTNGRLGFDYLIDNLADSAEGKFLPQLNYGIIDEVDSIILDAAQTPLVISGAPRLQSNLFHIVKEFVDTLI 249
Cdd:COG0653 167 AAYAADITYGTNNEFGFDYLRDNMVFSLEDMVQRGLNYAIVDEVDSILIDEARTPLIISGPAEDSTDLYYRINKLVPRLK 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 250 EDVHFKMKKTKKEIWLLNQGIEAAQSYFNVEDLYSEQAMVLVRNINLALRAQYLFESNVDYFVYNGDIVLIDRITGRMLP 329
Cdd:COG0653 247 RDGDYTVDEKARTVTLTEEGIEKVEKLLGIDNLYDPENIELVHHLNQALRAHALFKRDVDYIVKDGEVVIVDEFTGRLMP 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 330 GTKLQAGLHQAIEAKEGMEVSTDKSVMATITFQNLFKLFESFSGMTATGKLGESEFFDLYSKIVVQAPTDKAIQRIDEPD 409
Cdd:COG0653 327 GRRYSDGLHQAIEAKEGVKIQNENQTLASITFQNYFRMYEKLAGMTGTADTEAEEFREIYGLDVVVIPTNRPMIRKDEPD 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 410 KVFRSVDEKNIAMIHDIVELHETGRPVLLITRTAEAAEYFSKVLFQMDIPNNLLIAQNVAKEAQMIAEAGQIGSMTVATS 489
Cdd:COG0653 407 LVYKTEEEKFNAVVEDIKERHEKGQPVLVGTTSIEKSELLSKLLKKEGIPHNVLNAKQHEREAEIVAQAGRPGAVTIATN 486
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 490 MAGRGTDIKLG---------------------------------EGVEALGGLAVIIHEHMENSRVDRQLRGRSGRQGDP 536
Cdd:COG0653 487 MAGRGTDIVLGgnpeflaaaeladrgleweeaiakikaewqaehEEVLEAGGLHVIGTERHESRRIDNQLRGRSGRQGDP 566
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 537 GSSCIYISLDDYLVKRW-SDsnlaennqlySLDA--QRLS-------QSNLFNRKVKqivvKAQRiseeqGVKAR--EM- 603
Cdd:COG0653 567 GSSRFYLSLEDDLMRIFgSD----------RIKGmmDKLGmeegepiEHKMVSKAIE----NAQK-----KVEGRnfDIr 627
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 604 ---------ANEfeksisiQRDLVYEERNRVLEIDD--------------------------AENRDFKALAKDVFEMF- 647
Cdd:COG0653 628 knlleyddvMND-------QRKVIYEQRREILEGEDlsetildmredviedlvdeyipegsyPEQWDLEGLEEALKELFg 700
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 648 -------VNEEKVLTKSRVVEYIYqnlsfqfnkDVACVNFKDKQAAVTF-LLEQFEKQlalnrknmqsayyynifvqkVF 719
Cdd:COG0653 701 ldlpieeWLDEEGLDEEELRERLL---------EAADEAYEEKEEELGPeVMRELERV--------------------VL 751
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....*....
gi 582840389 720 LKAIDSCWLEQVDYLQQLKASVNQRQNGQRNAIFEYHRVALDSFEVMTRNIKKRMVKNI 778
Cdd:COG0653 752 LQVLDRKWREHLDAMDHLRQGIGLRGYAQKDPLVEYKREAFELFEEMLDSIKEEVVRYL 810
|
|
| secA |
TIGR00963 |
preprotein translocase, SecA subunit; The proteins SecA-F and SecY, not all of which are ... |
24-770 |
0e+00 |
|
preprotein translocase, SecA subunit; The proteins SecA-F and SecY, not all of which are necessary, comprise the standard prokaryotic protein translocation apparatus. Other, specialized translocation systems also exist but are not as broadly distributed. This model describes SecA, an essential member of the apparatus. This model excludes SecA2 of the accessory secretory system. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273366 [Multi-domain] Cd Length: 742 Bit Score: 678.21 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 24 INTWSDEVKSYSDDALKQKTIEFKERLASGVDTLDTLLPEAYAVAREASWRVLGMYPKEVQLIGAIVLHEGNIAEMQTGE 103
Cdd:TIGR00963 1 INALEEDYEKLSDEELRNKTNEFKDRLAKQGETLDDLLPEAFAVVREASKRVLGMRPFDVQLIGGIALHKGKIAEMKTGE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 104 GKTLTATMPLYLNALSGKGTYLITTNDYLAKRDFEEMQPLYEWLGLTaslgfVDIVDYEYQKGEKRNIYEHDIIYTTNGR 183
Cdd:TIGR00963 81 GKTLTATLPAYLNALTGKGVHVVTVNDYLAQRDAEWMGQVYRFLGLS-----VGLILSGMSPEERREAYACDITYGTNNE 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 184 LGFDYLIDNLADSAEGKFLPQLNYGIIDEVDSIILDAAQTPLVISGAPRLQSNLFHIVKEFVDTLIEDVHFKMKKTKKEI 263
Cdd:TIGR00963 156 LGFDYLRDNMAHSKEEKVQRPFHFAIIDEVDSILIDEARTPLIISGPAEKSTELYVQANKFAKALEKEVDYEVDEKNRAV 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 264 WLLNQGIEAAQSYFNVEDLYSEQAMVLVRNINLALRAQYLFESNVDYFVYNGDIVLIDRITGRMLPGTKLQAGLHQAIEA 343
Cdd:TIGR00963 236 LLTEQGMKKAEDLLGVDNLYDLENSPLIHYINNALKAKELFQKDVDYIVRDGEVVIVDEFTGRIMEGRRWSDGLHQAIEA 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 344 KEGMEVSTDKSVMATITFQNLFKLFESFSGMTATGKLGESEFFDLYSKIVVQAPTDKAIQRIDEPDKVFRSVDEKNIAMI 423
Cdd:TIGR00963 316 KEGVEIQNENQTLATITYQNFFRLYEKLSGMTGTAKTEEEEFRKIYNLEVVVVPTNRPVIRKDRPDLVYKTEEEKWKAVV 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 424 HDIVELHETGRPVLLITRTAEAAEYFSKVLFQMDIPNNLLIAQNVAKEAQMIAEAGQIGSMTVATSMAGRGTDIKLgEGV 503
Cdd:TIGR00963 396 EEIKERHAKGQPVLVGTTSVEKSELLSNLLKERGIPHNVLNAKNHEREAEIIAQAGRKGAVTIATNMAGRGTDIKL-EEV 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 504 EALGGLAVIIHEHMENSRVDRQLRGRSGRQGDPGSSCIYISLDDYLVKRWSDSNLAENNQLYSLDAQRLSQSNLFNRKVK 583
Cdd:TIGR00963 475 KELGGLYVIGTERHESRRIDNQLRGRSGRQGDPGSSRFFLSLEDNLMRIFGGDRLEGLMRRLGMDDDEPIESKMVSRALE 554
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 584 qivvKAQRISEEQGVKAREMANEFEKSISIQRDLVYEERNRVLEIDDAENRDFKALAK---DVFEMFVNEEKV--LTKSR 658
Cdd:TIGR00963 555 ----SAQKRVEGRNFDIRKQLLEYDDVLNKQREVIYAERRRVLESEDLSELILQMLEStldRIVDAYINEEKLseEWDLE 630
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 659 V-VEYIYQNLSFQFNKDVACVNFKDKQAAVTFLLEQFEKQLALnRKNMQSAYYYNIFVQKVFLKAIDSCWLEQVDYLQQL 737
Cdd:TIGR00963 631 GlIEKLKTLFLLDGDLTPEDLENLTSEDLKELLLEKIRAAYDE-KEEQLESERMREFERYVLLQSIDRKWKEHLDAMDLL 709
|
730 740 750
....*....|....*....|....*....|...
gi 582840389 738 KASVNQRQNGQRNAIFEYHRVALDSFEVMTRNI 770
Cdd:TIGR00963 710 REGIGLRSYGQKDPLIEYKNEGFNLFEEMLEDI 742
|
|
| secA |
PRK12903 |
preprotein translocase subunit SecA; Reviewed |
11-779 |
0e+00 |
|
preprotein translocase subunit SecA; Reviewed
Pssm-ID: 237258 [Multi-domain] Cd Length: 925 Bit Score: 604.35 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 11 ELRLKSirKIVKRINTWSDEVKSYSDDALKQKTIEFKERLASGVdTLDTLLPEAYAVAREASWRVLGMYPKEVQLIGAIV 90
Cdd:PRK12903 13 EMRIAE--KILKQINDLEPYYRNLTDEELANKTNEFKDRLKNGE-TLEDIRVEAFAVAREATKRVLGKRPYDVQIIGGII 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 91 LHEGNIAEMQTGEGKTLTATMPLYLNALSGKGTYLITTNDYLAKRDFEEMQPLYEWLGLTASLGFVDIvdyeyQKGEKRN 170
Cdd:PRK12903 90 LDLGSVAEMKTGEGKTITSIAPVYLNALTGKGVIVSTVNEYLAERDAEEMGKVFNFLGLSVGINKANM-----DPNLKRE 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 171 IYEHDIIYTTNGRLGFDYLIDNLADSAEGKFLPQLNYGIIDEVDSIILDAAQTPLVISGAPRLQSNLFHIVKEFVDTLIE 250
Cdd:PRK12903 165 AYACDITYSVHSELGFDYLRDNMVSSKEEKVQRGLNFCLIDEVDSILIDEAKTPLIISGGQSNDSNLYLAADQFVRTLKE 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 251 DvHFKMKKTKKEIWLLNQGIEAAQSYFNVEDLYSEQAMVLVRNINLALRAQYLFESNVDYFVYNGDIVLIDRITGRMLPG 330
Cdd:PRK12903 245 D-DYKIDEETKAISLTEKGIKKANKFFKLKNLYDIENSELVHRIQNALRAHKVMKEDVEYIVRDGKIELVDQFTGRIMEG 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 331 TKLQAGLHQAIEAKEGMEVSTDKSVMATITFQNLFKLFESFSGMTATGKLGESEFFDLYSKIVVQAPTDKAIQRIDEPDK 410
Cdd:PRK12903 324 RSYSEGLQQAIQAKEMVEIEPETKTLATITYQNFFRLFKKLSGMTGTAKTEEQEFIDIYNMRVNVVPTNKPVIRKDEPDS 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 411 VFRSVDEKNIAMIHDIVELHETGRPVLLITRTAEAAEYFSKVLFQMDIPNNLLIAQNVAKEAQMIAEAGQIGSMTVATSM 490
Cdd:PRK12903 404 IFGTKHAKWKAVVKEVKRVHKKGQPILIGTAQVEDSETLHELLLEANIPHTVLNAKQNAREAEIIAKAGQKGAITIATNM 483
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 491 AGRGTDIKLGEGVEALGGLAVIIHEHMENSRVDRQLRGRSGRQGDPGSSCIYISLDDYLVKRWsdSNLAENNQLYSLDAQ 570
Cdd:PRK12903 484 AGRGTDIKLSKEVLELGGLYVLGTDKAESRRIDNQLRGRSGRQGDVGESRFFISLDDQLFRRF--SNFDKIKEAFKKLGD 561
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 571 RLSQSNLFNRkvkqIVVKAQRISEEQGVKAREMANEFEKSISIQRDLVYEERNRVLEIDDAE---NRDFKALAKDV--FE 645
Cdd:PRK12903 562 DEIKSKFFSK----ALLNAQKKIEGFNFDTRKNVLDYDDVIRQQRDLIYAQRDLILIADDLShviEKMISRAVEQIlkNS 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 646 MFVNEEKVLTKSRVVEYIYQNLSFQFNKDVACVNFK--DKQAAVTFLLEQFEKQLALNRKNMQSAY---YYNIFVQKVFL 720
Cdd:PRK12903 638 FIILKNNTINYKELVEFLNDNLLRITHFKFSEKDFEnyHKEELAQYLIEALNEIYFKKRQVILDKIalnTFFESERYIIL 717
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*....
gi 582840389 721 KAIDSCWLEQVDYLQQLKASVNQRQNGQRNAIFEYHRVALDSFEVMTRNIKKRMVKNIC 779
Cdd:PRK12903 718 SALDKYWQNHIDTMDKLRSGVNLVQYSQKNPYQVYTEEGTKKFNILLQEIAYDVIVSLF 776
|
|
| SecA_DEAD |
smart00957 |
SecA DEAD-like domain; SecA protein binds to the plasma membrane where it interacts with ... |
3-386 |
0e+00 |
|
SecA DEAD-like domain; SecA protein binds to the plasma membrane where it interacts with proOmpA to support translocation of proOmpA through the membrane. SecA protein achieves this translocation, in association with SecY protein, in an ATP dependent manner. This domain represents the N-terminal ATP-dependent helicase domain, which is related to the.
Pssm-ID: 214937 [Multi-domain] Cd Length: 380 Bit Score: 574.76 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 3 HKLDVTINELRLKSIRKIVKRINTWSDEVKSYSDDALKQKTIEFKERLASGvDTLDTLLPEAYAVAREASWRVLGMYPKE 82
Cdd:smart00957 2 KKLFGSKNDRELKRLRKIVDQINALEPEMEALSDEELRAKTAEFKERLAEG-ESLDDLLPEAFAVVREAAKRVLGMRHFD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 83 VQLIGAIVLHEGNIAEMQTGEGKTLTATMPLYLNALSGKGTYLITTNDYLAKRDFEEMQPLYEWLGLTaslgfVDIVDYE 162
Cdd:smart00957 81 VQLIGGIVLHEGKIAEMKTGEGKTLVATLPAYLNALTGKGVHVVTVNDYLAKRDAEWMGPLYEFLGLT-----VGVIVSG 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 163 YQKGEKRNIYEHDIIYTTNGRLGFDYLIDNLADSAEGKFLPQLNYGIIDEVDSIILDAAQTPLVISG-APRLQSNLFHIV 241
Cdd:smart00957 156 MSPEERRAAYAADITYGTNNEFGFDYLRDNMAFSKEDKVQRGLNYAIVDEVDSILIDEARTPLIISGpAEDESSDLYHRA 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 242 KEFVDTLIEDVHFKMKKTKKEIWLLNQGIEAAQSYFNVEDLYSEQAMVLVRNINLALRAQYLFESNVDYFVYNGDIVLID 321
Cdd:smart00957 236 DKFVPRLKEDEDYTVDEKSRTVELTEEGIEKAEKLLGIDNLYDPENIELLHHVNQALRAHYLFKRDVDYIVRDGEVVIVD 315
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 582840389 322 RITGRMLPGTKLQAGLHQAIEAKEGMEVSTDKSVMATITFQNLFKLFESFSGMTATGKLGESEFF 386
Cdd:smart00957 316 EFTGRVMEGRRYSDGLHQAIEAKEGVEIQEENQTLATITFQNYFRMYKKLSGMTGTAKTEAEEFR 380
|
|
| secA |
CHL00122 |
preprotein translocase subunit SecA; Validated |
9-784 |
0e+00 |
|
preprotein translocase subunit SecA; Validated
Pssm-ID: 214371 [Multi-domain] Cd Length: 870 Bit Score: 573.48 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 9 INELRLKSIRKIVKRINTWSDEVKSYSDDALKQKTIEFKERLASGVDtLDTLLPEAYAVAREASWRVLGMYPKEVQLIGA 88
Cdd:CHL00122 7 NNKSKLNKYQTLVNQINLLEEELKNLTDTELRSKTNKLKKRLSNGQN-LNKIIPESFALTREASFRTLGLRHFDVQLIGG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 89 IVLHEGNIAEMQTGEGKTLTATMPLYLNALSGKGTYLITTNDYLAKRDFEEMQPLYEWLGLTASLgfvdiVDYEYQKGEK 168
Cdd:CHL00122 86 LVLNDGKIAEMKTGEGKTLVATLPAYLNALTGKGVHIVTVNDYLAKRDQEWMGQIYRFLGLTVGL-----IQEGMSSEER 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 169 RNIYEHDIIYTTNGRLGFDYLIDNLADSAEGKFLPQLNYGIIDEVDSIILDAAQTPLVISGAPRLQSNLFHIVKEFVDTL 248
Cdd:CHL00122 161 KKNYLKDITYVTNSELGFDYLRDNMALSLSDVVQRPFNYCIIDEVDSILIDEARTPLIISGQSKTNIDKYIVADELAKYL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 249 IEDVHFKMKKTKKEIWLLNQGIEAAQSYFNVEDLYSEQAMVLVRNINlALRAQYLFESNVDYFVYNGDIVLIDRITGRML 328
Cdd:CHL00122 241 EKNVHYEVDEKNKNVILTEQGILFIEKILKIEDLYSANDPWIPYILN-ALKAKELFFKNVHYIVRNNEIIIVDEFTGRIM 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 329 PGTKLQAGLHQAIEAKEGMEVSTDKSVMATITFQNLFKLFESFSGMTATGKLGESEFFDLYSKIVVQAPTDKAIQRIDEP 408
Cdd:CHL00122 320 PGRRWSDGLHQAIEAKENLPIRQETETLASITYQNFFLLYPKLSGMTGTAKTEELEFEKIYNLEVVCIPTHRPMLRKDLP 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 409 DKVFRSVDEKNIAMIHDIVELHETGRPVLLITRTAEAAEYFSKVLFQMDIPNNLLIA--QNVAKEAQMIAEAGQIGSMTV 486
Cdd:CHL00122 400 DLIYKDELSKWRAIADECLQMHQTGRPILIGTTTIEKSELLSQLLKEYRLPHQLLNAkpENVRRESEIVAQAGRKGSITI 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 487 ATSMAGRGTDIKLG------------------------------------------------------------------ 500
Cdd:CHL00122 480 ATNMAGRGTDIILGgnpefklkkelydlllsyksnekistisqnflnilnslkndlkflslsdfenlkilneaseisipk 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 501 --------------------------EGVEALGGLAVIIHEHMENSRVDRQLRGRSGRQGDPGSSCIYISLDDYLVKRWS 554
Cdd:CHL00122 560 nsyqlslrflynellekykklqekekKIVKKLGGLYVIGTERHESRRIDNQLRGRAGRQGDPGSSRFFLSLEDNLLRIFG 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 555 DSNLAENNQLYSLDAQRLsQSNLFNRKVKQivvkAQRISEEQGVKAREMANEFEKSISIQRDLVYEERNRVLEidDAENR 634
Cdd:CHL00122 640 GDKIQNLMQTLNLDDEPL-ESKLLSKSLDS----AQKKVEEYYYDQRKQLFEYDQVLNKQRKAIYSERRKILE--SQSLR 712
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 635 D----FKALAKDVFEMFVNEEKVLTKSRV--VEYIYQNLSFQFNKDVACVNFKDKQAAVTFLLEQFEKQLALNRKNMQSA 708
Cdd:CHL00122 713 DwilaYGEQVIDDIITFLKSRKNPNNKFInlINKFKELLKLPLCFNKSDLNTLNSGELKKFLYQQFWISYDLKELYLEQI 792
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 582840389 709 Y--YYNIFVQKVFLKAIDSCWLEQVDYLQQLKASVNQRQNGQRNAIFEYHRVALDSFEVMTRNIKKRMVKNICQSMIT 784
Cdd:CHL00122 793 GtgLMRELERSLLLQQIDKSWKEHLQKMSLLREAIGWRSYGQKDPLIEYKNEAFNLFINMINHIRHLVIYDLFRSSIL 870
|
|
| SecA_DEAD |
pfam07517 |
SecA DEAD-like domain; SecA protein binds to the plasma membrane where it interacts with ... |
1-385 |
0e+00 |
|
SecA DEAD-like domain; SecA protein binds to the plasma membrane where it interacts with proOmpA to support translocation of proOmpA through the membrane. SecA protein achieves this translocation, in association with SecY protein, in an ATP dependent manner. This domain represents the N-terminal ATP-dependent helicase domain, which is related to the pfam00270.
Pssm-ID: 462190 [Multi-domain] Cd Length: 379 Bit Score: 553.26 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 1 MKHKLDvTINELRLKSIRKIVKRINTWSDEVKSYSDDALKQKTIEFKERLASGvDTLDTLLPEAYAVAREASWRVLGMYP 80
Cdd:pfam07517 1 LKKIFG-SPNERDLKRLRKIVDQINALEEELKALSDEELRAKTDELRERLREG-ESLDDILPEAFALVREAAKRVLGMRH 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 81 KEVQLIGAIVLHEGNIAEMQTGEGKTLTATMPLYLNALSGKGTYLITTNDYLAKRDFEEMQPLYEWLGLTaslgfVDIVD 160
Cdd:pfam07517 79 YDVQLIGGLVLHEGKIAEMKTGEGKTLTATLPAYLNALSGKGVHVVTVNDYLAKRDAEWMGPLYEFLGLT-----VGVIT 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 161 YEYQKGEKRNIYEHDIIYTTNGRLGFDYLIDNLADSAEGKFLPQLNYGIIDEVDSIILDAAQTPLVISGAPRLQSNLFHI 240
Cdd:pfam07517 154 SDMDPEERRAAYNADITYGTNNELGFDYLRDNMATSKEDKVQRGLNFAIVDEVDSILIDEARTPLIISGPSEDDSELYRE 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 241 VKEFVDTLIEDVHFKMKKTKKEIWLLNQGIEAAQSYFNVEDLYSEQAMVLVRNINLALRAQYLFESNVDYFVYNGDIVLI 320
Cdd:pfam07517 234 ADRLVKSLEEDGDYEIDEKSKNVELTEKGIEKIEKLLGIDNLYDPENVELLHHINQALKAHHLFKRDVDYIVRDGEVVIV 313
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 582840389 321 DRITGRMLPGTKLQAGLHQAIEAKEGMEVSTDKSVMATITFQNLFKLFESFSGMTATGKLGESEF 385
Cdd:pfam07517 314 DEFTGRVMPGRRWSDGLHQAIEAKEGVEITPESQTLASITYQNFFRLYPKLSGMTGTAKTEAEEF 378
|
|
| secA |
PRK12898 |
preprotein translocase subunit SecA; Reviewed |
3-601 |
1.75e-176 |
|
preprotein translocase subunit SecA; Reviewed
Pssm-ID: 237253 [Multi-domain] Cd Length: 656 Bit Score: 522.26 E-value: 1.75e-176
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 3 HKLDVTINELRLKSIRKIVKRINTWSDEVKSYSDDALKQKTIEFKERLASGVDTLDTLLPEAYAVAREASWRVLGMYPKE 82
Cdd:PRK12898 27 GRLAGRVRGRAARRQRLLADRVLAAAEALAGLSEEALRARSLALRARLRARDGFRDALLAEAFALVREASGRVLGQRHFD 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 83 VQLIGAIVLHEGNIAEMQTGEGKTLTATMPLYLNALSGKGTYLITTNDYLAKRDFEEMQPLYEWLGLTASlgfvdIVDYE 162
Cdd:PRK12898 107 VQLMGGLALLSGRLAEMQTGEGKTLTATLPAGTAALAGLPVHVITVNDYLAERDAELMRPLYEALGLTVG-----CVVED 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 163 YQKGEKRNIYEHDIIYTTNGRLGFDYLIDNLA-------------------DSAEGKFLPQLNYGIIDEVDSIILDAAQT 223
Cdd:PRK12898 182 QSPDERRAAYGADITYCTNKELVFDYLRDRLAlgqrasdarlaleslhgrsSRSTQLLLRGLHFAIVDEADSVLIDEART 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 224 PLVISGAPRLQSNL--FHIVKEFVDTLIEDVHFKMKKTKKEIWLLNQG---IEAAqsyfnVEDLYSEQaMVLVRN---IN 295
Cdd:PRK12898 262 PLIISAPAKEADEAevYRQALELAAQLKEGEDYTIDAAEKRIELTEAGrarIAEL-----AESLPPAW-RGAVRReelVR 335
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 296 LALRAQYLFESNVDYFVYNGDIVLIDRITGRMLPGTKLQAGLHQAIEAKEGMEVSTDKSVMATITFQNLFKLFESFSGMT 375
Cdd:PRK12898 336 QALSALHLFRRDEHYIVRDGKVVIVDEFTGRVMPDRSWEDGLHQMIEAKEGCELTDPRETLARITYQRFFRRYLRLAGMT 415
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 376 ATGKLGESEFFDLYSKIVVQAPTDKAIQRIDEPDKVFRSVDEKNIAMIHDIVELHETGRPVLLITRTAEAAEYFSKVLFQ 455
Cdd:PRK12898 416 GTAREVAGELWSVYGLPVVRIPTNRPSQRRHLPDEVFLTAAAKWAAVAARVRELHAQGRPVLVGTRSVAASERLSALLRE 495
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 456 MDIPNNLLIAQNVAKEAQMIAEAGQIGSMTVATSMAGRGTDIKLGEGVEALGGLAVIIHEHMENSRVDRQLRGRSGRQGD 535
Cdd:PRK12898 496 AGLPHQVLNAKQDAEEAAIVARAGQRGRITVATNMAGRGTDIKLEPGVAARGGLHVILTERHDSARIDRQLAGRCGRQGD 575
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 582840389 536 PGSSCIYISLDDYLVKRWSDSnLAENNQLYSLDAQRLSQSnlfnrKVKQIVVKAQRISEEQGVKAR 601
Cdd:PRK12898 576 PGSYEAILSLEDDLLQSFLGS-RGLAIRRMELLGPRGGRA-----LGALLLRRAQRRAERLHARAR 635
|
|
| secA |
PRK12901 |
preprotein translocase subunit SecA; Reviewed |
10-785 |
2.37e-154 |
|
preprotein translocase subunit SecA; Reviewed
Pssm-ID: 237256 [Multi-domain] Cd Length: 1112 Bit Score: 479.13 E-value: 2.37e-154
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 10 NELRLKSIRKIVKRINTWSDEVKSYSDDALKQKTIEFKERLASGV----------------------------------- 54
Cdd:PRK12901 13 SERDLKEIQPIVEKIKAEYPELEALSNDELRAKTDEFKQYIKEAVadidakieelkaeaiesldiderediyaqidklek 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 55 -------DTLDTLLPEAYAVAREA---------------------------------------SWRVLG------MYPKE 82
Cdd:PRK12901 93 eayeileKVLDEILPEAFAIVKETarrfaeneeievtatdfdrelaatkdfvtiegdkaiwknHWDAGGneitwdMVHYD 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 83 VQLIGAIVLHEGNIAEMQTGEGKTLTATMPLYLNALSGKGTYLITTNDYLAKRDFEEMQPLYEWLGLTaslgfVDIVD-Y 161
Cdd:PRK12901 173 VQLIGGVVLHQGKIAEMATGEGKTLVATLPVYLNALTGNGVHVVTVNDYLAKRDSEWMGPLYEFHGLS-----VDCIDkH 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 162 EYQKGEKRNIYEHDIIYTTNGRLGFDYLIDNLADSAEGKFLPQLNYGIIDEVDSIILDAAQTPLVISG-APRLQSNLFHI 240
Cdd:PRK12901 248 QPNSEARRKAYNADITYGTNNEFGFDYLRDNMAHSPEDLVQRKHNYAIVDEVDSVLIDDARTPLIISGpVPKGDDQEFEE 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 241 VKEFVDTLIE------------------------------DVHFKMKKTKKEIWLLN-QGIEA----------------- 272
Cdd:PRK12901 328 LKPRVERLVEaqrklatqflaeakkliaegdkkegglallRAYRGLPKNKALIKFLSeEGIKAllqktenfymqdnnrem 407
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 273 ----AQSYFNVE-----------------------------DLYSEQAMV-----------------LVRN--------- 293
Cdd:PRK12901 408 pevdEELYFVIDeknnsveltdkgidyitgndedpdffvlpDIGTELAEIeneggldeeeeaekkeeLFQDysvkservh 487
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 294 -INLALRAQYLFESNVDYFVYNGDIVLIDRITGRMLPGTKLQAGLHQAIEAKEGMEVSTDKSVMATITFQNLFKLFESFS 372
Cdd:PRK12901 488 tLNQLLKAYTLFEKDDEYVVMDGKVKIVDEQTGRIMEGRRYSDGLHQAIEAKENVKIEAATQTFATITLQNYFRMYHKLA 567
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 373 GMTATGKLGESEFFDLYSKIVVQAPTDKAIQRIDEPDKVFRSVDEKNIAMIHDIVELHETGRPVLLITRTAEAAEYFSKV 452
Cdd:PRK12901 568 GMTGTAETEAGEFWDIYKLDVVVIPTNRPIARKDKEDLVYKTKREKYNAVIEEITELSEAGRPVLVGTTSVEISELLSRM 647
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 453 LFQMDIPNNLLIAQNVAKEAQMIAEAGQIGSMTVATSMAGRGTDIKLGEGVEALGGLAVIIHEHMENSRVDRQLRGRSGR 532
Cdd:PRK12901 648 LKMRKIPHNVLNAKLHQKEAEIVAEAGQPGTVTIATNMAGRGTDIKLSPEVKAAGGLAIIGTERHESRRVDRQLRGRAGR 727
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 533 QGDPGSSCIYISLDDYLVKRWSDSNLAENNQLYSLDAQRLSQSNLFNRKVKqivvKAQRISEEQGVKAREMANEFEKSIS 612
Cdd:PRK12901 728 QGDPGSSQFYVSLEDNLMRLFGSERIAKVMDRMGLKEGEVIQHSMISKSIE----RAQKKVEENNFGIRKRLLEYDDVMN 803
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 613 IQRDLVYEERNRVLE------------IDDAEN--------RDFKALAKDVFEMF-----VNEE--KVLTKSRVVEYIYQ 665
Cdd:PRK12901 804 SQREVIYKRRRHALMgerlgmdianmiYDVCEAivennkvaNDYKGFKFELIRTLamespITEEefNKLKKDELTDKLYD 883
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 666 nlsfqfnkdVACVNFKDKQAAVTFLLEQFEKQLALNRKNMqsayYYNIFV------------------------------ 715
Cdd:PRK12901 884 ---------AALENYQRKMERIAEIAFPVIKQVYEEQGNM----YERIVVpftdgkrtlnvvtnlkeayetegkeivkdf 950
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 582840389 716 -QKVFLKAIDSCWLEQVDYLQQLKASVNQRQNGQRNAIFEYhrvALDSFEVMtrnikKRMVKNICQSMITF 785
Cdd:PRK12901 951 eKNITLHIIDEAWKEHLREMDELKQSVQNASYEQKDPLLIY---KFESFELF-----KNMVDKVNREVISF 1013
|
|
| SecA2_Mycobac |
TIGR04221 |
accessory Sec system translocase SecA2, Actinobacterial type; Members of this family are the ... |
11-790 |
1.61e-137 |
|
accessory Sec system translocase SecA2, Actinobacterial type; Members of this family are the SecA2 subunit of the Mycobacterial type of accessory secretory system. This family is quite different SecA2 of the Staph/Strep type (TIGR03714).
Pssm-ID: 275062 [Multi-domain] Cd Length: 762 Bit Score: 425.01 E-value: 1.61e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 11 ELRLKSIRKIVKRINTWSDEVKSYSDDALKQKTIEFKErLASGVDtldtlLPEAYAVAREASWRVLGMYPKEVQLIGAIV 90
Cdd:TIGR04221 14 ERNQKRSLAIVPAAASRMKELSALDDEELTKAARDLVL-SGEAAD-----AAQFLAILREAAERTLGMRPFDVQLLGALR 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 91 LHEGNIAEMQTGEGKTLTATMPLYLNALSGKGTYLITTNDYLAKRDFEEMQPLYEWLGLTaslgfVDIVDYEYQKGEKRN 170
Cdd:TIGR04221 88 LLAGDVIEMATGEGKTLAGAMAATGFALLGKRVHVVTVNDYLARRDAEWMGPLVDFFGLT-----VGWVTEDSTPDERRA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 171 IYEHDIIYTTNGRLGFDYLIDNLADSAEGKFLPQLNYGIIDEVDSIILDAAQTPLVISGA-PRLQSNlfHIVKEFVDTLI 249
Cdd:TIGR04221 163 AYACDVTYASVNEIGFDVLRDQLVTDRADLVQPAADVALIDEADSVLVDEALVPLVLAGNePGEAPR--GRITDLVRRLR 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 250 EDVHFKMKKTKKEIWLLNQGIEAAQSYFNVEDLYS-EQAMVLVRNINLALRAQYLFESNVDYFVYNGDIVLIDRITGRML 328
Cdd:TIGR04221 241 EDKHYTVDEDGRNVHLTEDGARAVEAELGIDDLYSeEHVGTTLVQVNVALHAHALLIRDVHYIVRDGKVALIDASRGRVA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 329 PGTKLQAGLHQAIEAKEGMEVSTDKSVMATITFQNLFKLFESFSGMTATGKL-GES--EFFDLYSKIVvqaPTDKAIQRI 405
Cdd:TIGR04221 321 QLQRWPDGLQAAVEAKEGLEVTEGGEVLDTITVQALIGRYPTVCGMTGTAVAaGEQlrQFYDLGVSVI---PPNTPNIRF 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 406 DEPDKVFRSVDEKNIAMIHDIVELHETGRPVLLITRTAEAAEYFSKVLFQMDIPNNLLIAQNVAKEAQMIAEAGQIGSMT 485
Cdd:TIGR04221 398 DEADRVYATAAEKNDAIVEEIAEVHKTGQPVLVGTQDVAESEELAEALLEAGVPCNVLNAKNDAEEAAIIAEAGDIGAVT 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 486 VATSMAGRGTDIKLGEGVEA-------LGGLAVIIHEHMENSRVDRQLRGRSGRQGDPGSSCIYISLDDYLVKRWSDSNl 558
Cdd:TIGR04221 478 VSTQMAGRGTDIRLGGSDEAdhdrvaeLGGLHVIGTGRHRTARLDNQLRGRAGRQGDPGSSVFFVSLEDDVVAVGGAGE- 556
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 559 aennqlySLDAQRLSQSNLFNRKVKQIVVKAQRISEEQGVKAREMANEFEKSISIQRDLVYEERNRVLEIDDAenrdfka 638
Cdd:TIGR04221 557 -------TVPAQPAEDGRIESPRVQDFVDHAQRVAEGQLLEIHANTWRYNQLIAQQRDIIDERRETLLDTDTA------- 622
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 639 lAKDVFEmfvneekvltksRVVEYiYQNLSFQFNKDVacvnfkdkqaavtflLEQFEKQLALnrknmqsaYYynifvqkv 718
Cdd:TIGR04221 623 -WQELSE------------RAADR-AAELKKEVSEDA---------------LERAAREIML--------YH-------- 657
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 582840389 719 flkaIDSCWLEQVDYLQQLKASVNQRQNGQRNAIFEYHRVALDSFEVMTRNIKKRMVKNICQSMITFDKEGM 790
Cdd:TIGR04221 658 ----LDRGWAEHLAYLDDVRESIHLRALGRETPLDEFHRMAVRAFKELAQRAVDKAVETFEEVEIDADGAHL 725
|
|
| DEXDc_SecA |
cd17928 |
DEXD-box helicase domain of SecA; SecA is a part of the Sec translocase that transports the ... |
38-398 |
2.72e-93 |
|
DEXD-box helicase domain of SecA; SecA is a part of the Sec translocase that transports the vast majority of bacterial and ER-exported proteins. SecA binds both the signal sequence and the mature domain of the preprotein emerging from the ribosome. SecA belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350686 [Multi-domain] Cd Length: 230 Bit Score: 291.36 E-value: 2.72e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 38 ALKQKTIEFKERLASGvDTLDTLLPEAYAVAREASWRVLGMYPKEVQLIGAIVLHEGNIAEMQTGEGKTLTATMPLYLNA 117
Cdd:cd17928 1 ELRAKTDELRERLAKG-ETLDDLLPEAFALVREAARRVLGMRPFDVQLIGGLVLHEGKIAEMKTGEGKTLTATLPAYLNA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 118 LSGKGTYLITTNDYLAKRDFEEMQPLYEWLGLTaslgfVDIVDYEYQKGEKRNIYEHDIIYTTNGRLGFDYLIDNLADSA 197
Cdd:cd17928 80 LTGKGVHVVTVNDYLARRDAEWMGPLYEFLGLT-----VGVILSDMSPDERREAYAADITYGTNNELGFDYLRDNMVTSK 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 198 EGKFLPQLNYGIIDEVDSIILDAAQTPLVISGaprlqsnlfhivkefvdtliedvhfkmkktkkeiwllnqgieaaqsyf 277
Cdd:cd17928 155 EDLVQRGLNFAIVDEVDSILIDEARTPLIISG------------------------------------------------ 186
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 278 nvedlyseqamvlvrninlalraqylfesnvdyfvyngdivlidritgrmlpgtklqaglhqaieakegmevstdksVMA 357
Cdd:cd17928 187 -----------------------------------------------------------------------------TLA 189
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 582840389 358 TITFQNLFKLFESFSGMTATGKLGESEFFDLYSKIVVQAPT 398
Cdd:cd17928 190 TITFQNYFRLYPKLAGMTGTAKTEAEEFREIYNLDVVVIPT 230
|
|
| SF2_C_secA |
cd18803 |
C-terminal helicase domain of the protein translocase subunit secA; SecA is a component of the ... |
404-544 |
3.76e-70 |
|
C-terminal helicase domain of the protein translocase subunit secA; SecA is a component of the Sec translocase that transports the vast majority of bacterial and ER-exported proteins. SecA binds both the signal sequence and the mature domain of the preprotein emerging from the ribosome. SecA is a DEAD-like helicase belonging to superfamily (SF)2, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350190 [Multi-domain] Cd Length: 141 Bit Score: 226.66 E-value: 3.76e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 404 RIDEPDKVFRSVDEKNIAMIHDIVELHETGRPVLLITRTAEAAEYFSKVLFQMDIPNNLLIAQNVAKEAQMIAEAGQIGS 483
Cdd:cd18803 1 RKDLPDLVYKTEEEKWKAIVEEVKELHAKGQPVLVGTRSVEKSELLSALLKEEGIPHNVLNAKNHAREAEIIAEAGQKGA 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 582840389 484 MTVATSMAGRGTDIKLGEGVEALGGLAVIIHEHMENSRVDRQLRGRSGRQGDPGSSCIYIS 544
Cdd:cd18803 81 VTIATNMAGRGTDIKLGGNVEELGGLHVIGTERHESRRIDNQLRGRAGRQGDPGSSRFYLS 141
|
|
| SecA_PP_bind |
smart00958 |
SecA preprotein cross-linking domain; The SecA ATPase is involved in the insertion and ... |
234-342 |
1.68e-37 |
|
SecA preprotein cross-linking domain; The SecA ATPase is involved in the insertion and retraction of preproteins through the plasma membrane. This domain has been found to cross-link to preproteins, thought to indicate a role in preprotein binding. The pre-protein cross-linking domain is comprised of two sub domains that are inserted within the ATPase domain.
Pssm-ID: 214938 [Multi-domain] Cd Length: 114 Bit Score: 136.04 E-value: 1.68e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 234 QSNLFHIVKEFVDTLIEDV-HFKMKKTKKEIWLLNQGIEAAQSYFNVEDLYSEQAMVLVRNINLALRAQYLFESNVDYFV 312
Cdd:smart00958 5 SSELYKRADELVPTLKKDEeDYEVDEKSRQVALTEEGIEKAEKLLGIDNLYDPENIELVHHVNQALRAHKLFKRDVDYIV 84
|
90 100 110
....*....|....*....|....*....|
gi 582840389 313 YNGDIVLIDRITGRMLPGTKLQAGLHQAIE 342
Cdd:smart00958 85 RDGEVVIVDEFTGRVMPGRRWSDGLHQAIE 114
|
|
| SecA_PP_bind |
pfam01043 |
SecA preprotein cross-linking domain; The SecA ATPase is involved in the insertion and ... |
234-342 |
1.18e-35 |
|
SecA preprotein cross-linking domain; The SecA ATPase is involved in the insertion and retraction of preproteins through the plasma membrane. This domain has been found to cross-link to preproteins, thought to indicate a role in preprotein binding. The pre-protein cross-linking domain is comprised of two sub domains that are inserted within the ATPase domain.
Pssm-ID: 460039 [Multi-domain] Cd Length: 110 Bit Score: 130.61 E-value: 1.18e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 234 QSNLFHIVKEFVDTLIEDVHFKMKKTKKEIWLLNQGIEAAQSYFNVEDLYSEQAMVLVRNINLALRAQYLFESNVDYFVY 313
Cdd:pfam01043 2 STELYRQADKFVKQLKEDEDYEVDEKAKTVELTEEGIEKAEKLLGIDNLYDPENIELVHHINQALKAHHLFKRDVDYIVK 81
|
90 100
....*....|....*....|....*....
gi 582840389 314 NGDIVLIDRITGRMLPGTKLQAGLHQAIE 342
Cdd:pfam01043 82 DGEVVIVDEFTGRLMPGRRYSDGLHQAIE 110
|
|
| SecA_SW |
pfam07516 |
SecA Wing and Scaffold domain; SecA protein binds to the plasma membrane where it interacts ... |
588-780 |
9.76e-25 |
|
SecA Wing and Scaffold domain; SecA protein binds to the plasma membrane where it interacts with proOmpA to support translocation of proOmpA through the membrane. SecA protein achieves this translocation, in association with SecY protein, in an ATP dependent manner. This family is composed of two C-terminal alpha helical subdomains: the wing and scaffold subdomains.
Pssm-ID: 462189 [Multi-domain] Cd Length: 213 Bit Score: 102.96 E-value: 9.76e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 588 KAQRISEEQGVKAREMANEFEKSISIQRDLVYEERNRVLEIDDAENrDFKALAKDVFEMFVNEEKVLTKSR-------VV 660
Cdd:pfam07516 13 NAQKKVEGRNFDIRKNLLEYDDVMNQQREVIYAQRREILEGEDLKE-DILEMIEDVVDDIVDEYIPPEESPeewdlegLK 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 661 EYIYQNLSFQFN-KDVACVNFKDKQAAVTFLLEQFEKQLALNRKNMQSAYYyNIFVQKVFLKAIDSCWLEQVDYLQQLKA 739
Cdd:pfam07516 92 EALNEIFGLELPiSEWEEEEDLDKEELKERLLEAAEEAYEEKEEEIGPELM-RELERVVLLQVIDSKWKEHLDAMDQLRQ 170
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 582840389 740 SVNQRQNGQRNAIFEYHRVALDSFEVMTRNIKKRMVKNICQ 780
Cdd:pfam07516 171 GIGLRAYGQKDPLVEYKREGFELFEEMLDAIREEVVRYLFR 211
|
|
| SF2-N |
cd00046 |
N-terminal DEAD/H-box helicase domain of superfamily 2 helicases; The DEAD/H-like superfamily ... |
92-226 |
2.18e-13 |
|
N-terminal DEAD/H-box helicase domain of superfamily 2 helicases; The DEAD/H-like superfamily 2 helicases comprise a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This N-terminal domain contains the ATP-binding region.
Pssm-ID: 350668 [Multi-domain] Cd Length: 146 Bit Score: 68.20 E-value: 2.18e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 92 HEGNIAEMQTGEGKTLTATMPLYLNALS-GKGTYLITTNDYLAKRDFEEMQPLYEWlGLTaslgfVDIVDYEYQKGEKRN 170
Cdd:cd00046 1 GENVLITAPTGSGKTLAALLAALLLLLKkGKKVLVLVPTKALALQTAERLRELFGP-GIR-----VAVLVGGSSAEEREK 74
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 582840389 171 --IYEHDIIYTTNGRLGFDYLidnladSAEGKFLPQLNYGIIDEVDSIILDAAQTPLV 226
Cdd:cd00046 75 nkLGDADIIIATPDMLLNLLL------REDRLFLKDLKLIIVDEAHALLIDSRGALIL 126
|
|
| DEAD-like_helicase_N |
cd17912 |
N-terminal helicase domain of the DEAD-box helicase superfamily; The DEAD-like helicase ... |
96-158 |
8.10e-07 |
|
N-terminal helicase domain of the DEAD-box helicase superfamily; The DEAD-like helicase superfamily is a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. The N-terminal domain contains the ATP-binding region.
Pssm-ID: 350670 [Multi-domain] Cd Length: 81 Bit Score: 47.51 E-value: 8.10e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 96 IAEMQTGEGKTLTATMPLYLNALSGKGTYLITTNDYLAKRD---FEEMQ----PLYEWLGLTASLGFVDI 158
Cdd:cd17912 3 LHLGPTGSGKTLVAIQKIASAMSSGKSVLVVTPTKLLAHEIlivIDEIQ*ildPAAGWAWATRALLGLKA 72
|
|
| DEXDc |
smart00487 |
DEAD-like helicases superfamily; |
80-217 |
6.62e-05 |
|
DEAD-like helicases superfamily;
Pssm-ID: 214692 [Multi-domain] Cd Length: 201 Bit Score: 44.79 E-value: 6.62e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 80 PKEVQLIGAIVLHEGN---IAEMQTGEGKTLTATMPL--YLNALSGKGTYLITTNDYLAKRDFEEMQPLYEWLGLTASLG 154
Cdd:smart00487 9 LRPYQKEAIEALLSGLrdvILAAPTGSGKTLAALLPAleALKRGKGGRVLVLVPTRELAEQWAEELKKLGPSLGLKVVGL 88
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 582840389 155 FVDIVDYEYQKGEKRNIYehDIIYTTNGRLgFDYLIDNladsaeGKFLPQLNYGIIDEVDSII 217
Cdd:smart00487 89 YGGDSKREQLRKLESGKT--DILVTTPGRL-LDLLEND------KLSLSNVDLVILDEAHRLL 142
|
|
| DEAD-like_helicase_C |
cd09300 |
C-terminal helicase domain of the DEAD-like helicases; This hierarchy of DEAD-like helicases ... |
499-542 |
6.84e-05 |
|
C-terminal helicase domain of the DEAD-like helicases; This hierarchy of DEAD-like helicases is composed of two superfamilies, SF1 and SF2, that share almost identical folds and extensive structural similarity in their catalytic core. Helicases are involved in ATP-dependent RNA or DNA unwinding. Two distinct types of helicases exist, those forming toroidal, predominantly hexameric structures, and those that do not. SF1 and SF2 helicases do not form toroidal structures, while SF3-6 helicases do. Their conserved helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350171 [Multi-domain] Cd Length: 59 Bit Score: 41.38 E-value: 6.84e-05
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 582840389 499 LGEGVEALGGLAVIIHEHMENSRVDRQLRGRSGRQGDPGSSCIY 542
Cdd:cd09300 15 ALTGFDAPELNTIIVDKNLRSYRGLNQAFGRANRIYTFGGIVTY 58
|
|
| DEAD |
pfam00270 |
DEAD/DEAH box helicase; Members of this family include the DEAD and DEAH box helicases. ... |
96-214 |
3.22e-04 |
|
DEAD/DEAH box helicase; Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.
Pssm-ID: 425570 [Multi-domain] Cd Length: 165 Bit Score: 42.23 E-value: 3.22e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 582840389 96 IAEMQTGEGKTLTATMPLY--LNALSGKGTYLI---TTNdyLAKRDFEEMQPLYEWLGLTASLgFVDIVDYEYQKGEKRN 170
Cdd:pfam00270 18 LVQAPTGSGKTLAFLLPALeaLDKLDNGPQALVlapTRE--LAEQIYEELKKLGKGLGLKVAS-LLGGDSRKEQLEKLKG 94
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 582840389 171 IyehDIIYTTNGRLgFDYLIdnladsaEGKFLPQLNYGIIDEVD 214
Cdd:pfam00270 95 P---DILVGTPGRL-LDLLQ-------ERKLLKNLKLLVLDEAH 127
|
|
| |
