|
Name |
Accession |
Description |
Interval |
E-value |
| SpoU |
COG0566 |
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA ... |
3-243 |
9.77e-103 |
|
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA G18 (ribose-2'-O)-methylase SpoU is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440332 [Multi-domain] Cd Length: 265 Bit Score: 299.03 E-value: 9.77e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 3 DTVIVGRHAVREAIITGHPINKILIQEGIKKQqINEILKNAKDQKIIVQTVPKSKLDFLA-NAPHQGVAALIAPYEYADF 81
Cdd:COG0566 26 LFLAEGRHAVEEALKAGREIEELLVTEGALDR-LAELLALAKAAGIPVYEVSREVLDKLSgTETHQGVLAVVRPPEYADL 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 82 DQFLKQQKEKeglSTVLILDGLEDPHNLGSILRTADATGVDGVIIPKRRSVTLTQTVAKASTGAIEHVPVIRVTNLAKTI 161
Cdd:COG0566 105 EDLLAEAGEP---PLLLVLDGVQDPGNLGAILRSAAAFGVDGVILPKRRADPYNPKVVRASAGALFHVPVARVTNLADAL 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 162 DELKDNGFWVAGTEANNATDYRNLEADMSLAIVIGSEGQGMSRLVSDKCDFYIKIPMVGHVNSLNASVAASLMMYEVFRK 241
Cdd:COG0566 182 EELKEAGFWVVGTDLDGEASLYEVDLPGPVALVLGNEGKGLSRLVLEACDELVRIPMAGGVESLNVAVAAAILLYEAARQ 261
|
..
gi 584759422 242 RH 243
Cdd:COG0566 262 RR 263
|
|
| rRNA_methyl_3 |
TIGR00186 |
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases ... |
5-242 |
5.64e-85 |
|
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129290 [Multi-domain] Cd Length: 237 Bit Score: 252.65 E-value: 5.64e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 5 VIVGRHAVREAIITGhpiNKILIQEGIKKQQINEILKNAKDQKIIVQTVPKSKLDFLA-NAPHQGVAALIAPYEYADFDQ 83
Cdd:TIGR00186 3 YLYGKNAVLEALLNQ---QRVFILKGLESKRLKKLIQLAKKQGINIQLVDRQKLDQLTkGGNHQGIAAKVKPILYKDLND 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 84 fLKQQKEKEGLSTVLILDGLEDPHNLGSILRTADATGVDGVIIPKRRSVTLTQTVAKASTGAIEHVPVIRVTNLAKTIDE 163
Cdd:TIGR00186 80 -LYKTAKSKKQPFLLILDEITDPHNLGAILRTAEAFGVDGVILPKRRSAPLNSTVVKTSSGAVEYVPLARVTNLSRTITK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 164 LKDNGFWVAGTEAN-NATDYRNLEaDMSLAIVIGSEGQGMSRLVSDKCDFYIKIPMVGHVNSLNASVAASLMMYEVFRKR 242
Cdd:TIGR00186 159 LKESGFWTVGTDLDaQDTLYQVKL-TKPLALVVGNEGEGVSRLIKENCDFLIKIPMAGKVDSLNVSVAAGILLFEIKRQR 237
|
|
| SpoU-like_RlmB |
cd18103 |
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the ... |
97-238 |
2.03e-81 |
|
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the methylation of guanosine 2251, a modification conserved in the peptidyltransferase domain of 23S rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349976 Cd Length: 143 Bit Score: 240.36 E-value: 2.03e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 97 VLILDGLEDPHNLGSILRTADATGVDGVIIPKRRSVTLTQTVAKASTGAIEHVPVIRVTNLAKTIDELKDNGFWVAGTEA 176
Cdd:cd18103 2 LLILDGITDPHNLGAIIRSAEAFGVDGVIIPKRRSAPLTPTVAKASAGALEHLPIARVTNLARALEELKEAGFWIYGADG 81
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 584759422 177 NNATDYRNLEADMSLAIVIGSEGQGMSRLVSDKCDFYIKIPMVGHVNSLNASVAASLMMYEV 238
Cdd:cd18103 82 EAEKSLYDVDLTGPLALVLGSEGKGLRRLVLKNCDFLVKIPMAGKVDSLNVSVAAGIILYEI 143
|
|
| PRK11181 |
PRK11181 |
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB; |
6-242 |
1.32e-67 |
|
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB;
Pssm-ID: 183021 [Multi-domain] Cd Length: 244 Bit Score: 209.05 E-value: 1.32e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 6 IVGRHAVrEAIITGHP--INKILIQEGIKKQQINEILKNAKDQKIIVQTVPKSKLDFLAN-APHQGVAALIAP---YEYA 79
Cdd:PRK11181 5 IYGIHAV-QALLERAPerFIEVFVLKGREDKRLLPLINELEAQGIVIQLANRQTLDEKAEgAVHQGIIARVKPgrqLQEN 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 80 DFDQFLkQQKEKEGLstvLILDGLEDPHNLGSILRTADATGVDGVIIPKRRSVTLTQTVAKASTGAIEHVPVIRVTNLAK 159
Cdd:PRK11181 84 DLPDLL-ASLEQPFL---LILDGVTDPHNLGACLRSADAAGVHAVIVPKDRSAQLNATAKKVACGAAETVPLIRVTNLAR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 160 TIDELKDNGFWVAGT--EANNaTDYrnlEADM--SLAIVIGSEGQGMSRLVSDKCDFYIKIPMVGHVNSLNASVAASLMM 235
Cdd:PRK11181 160 TMRMLQEKNIWIVGTagEADH-TLY---QSKLtgPLALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGICL 235
|
....*..
gi 584759422 236 YEVFRKR 242
Cdd:PRK11181 236 FEAVRQR 242
|
|
| SpoU_methylase |
pfam00588 |
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet. |
97-236 |
1.84e-53 |
|
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet.
Pssm-ID: 425768 Cd Length: 142 Bit Score: 169.25 E-value: 1.84e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 97 VLILDGLEDPHNLGSILRTADATGVDGVIIPKRRSVTL-TQTVAKASTGAIEHVPVIRVTNLAKTIDELKDNGFWVAGTE 175
Cdd:pfam00588 3 VVVLDNIQDPGNLGAIIRTAAAFGADGLILVEPRSADPyNPKAIRASAGALFHLPLVVVDNLEEALKDLKEAGYAVVATS 82
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 584759422 176 ANnATDYRNLEADMSLAIVIGSEGQGMSRLVSDKCDFYIKIPMVGHVNSLNASVAASLMMY 236
Cdd:pfam00588 83 LG-GKSLYEIDFPKKVALVFGNEGTGLSNEVLELCDRLVRIPMSGDVESLNVAVAAAIALY 142
|
|
| SpoU_sub_bind |
smart00967 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
6-75 |
7.16e-16 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 214943 [Multi-domain] Cd Length: 70 Bit Score: 69.87 E-value: 7.16e-16
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 584759422 6 IVGRHAVREAIITGHPINKILIQEGIKKqQINEILKNAKDQKIIVQTVPKSKLDFLA-NAPHQGVAALIAP 75
Cdd:smart00967 1 IEGRHAVEEALKSGRRIKELYLTEGRAE-RLKELLKLAKERGIKVIEVSKKELDKLSgTANHQGVVAVVKP 70
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| SpoU |
COG0566 |
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA ... |
3-243 |
9.77e-103 |
|
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA G18 (ribose-2'-O)-methylase SpoU is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440332 [Multi-domain] Cd Length: 265 Bit Score: 299.03 E-value: 9.77e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 3 DTVIVGRHAVREAIITGHPINKILIQEGIKKQqINEILKNAKDQKIIVQTVPKSKLDFLA-NAPHQGVAALIAPYEYADF 81
Cdd:COG0566 26 LFLAEGRHAVEEALKAGREIEELLVTEGALDR-LAELLALAKAAGIPVYEVSREVLDKLSgTETHQGVLAVVRPPEYADL 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 82 DQFLKQQKEKeglSTVLILDGLEDPHNLGSILRTADATGVDGVIIPKRRSVTLTQTVAKASTGAIEHVPVIRVTNLAKTI 161
Cdd:COG0566 105 EDLLAEAGEP---PLLLVLDGVQDPGNLGAILRSAAAFGVDGVILPKRRADPYNPKVVRASAGALFHVPVARVTNLADAL 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 162 DELKDNGFWVAGTEANNATDYRNLEADMSLAIVIGSEGQGMSRLVSDKCDFYIKIPMVGHVNSLNASVAASLMMYEVFRK 241
Cdd:COG0566 182 EELKEAGFWVVGTDLDGEASLYEVDLPGPVALVLGNEGKGLSRLVLEACDELVRIPMAGGVESLNVAVAAAILLYEAARQ 261
|
..
gi 584759422 242 RH 243
Cdd:COG0566 262 RR 263
|
|
| rRNA_methyl_3 |
TIGR00186 |
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases ... |
5-242 |
5.64e-85 |
|
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129290 [Multi-domain] Cd Length: 237 Bit Score: 252.65 E-value: 5.64e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 5 VIVGRHAVREAIITGhpiNKILIQEGIKKQQINEILKNAKDQKIIVQTVPKSKLDFLA-NAPHQGVAALIAPYEYADFDQ 83
Cdd:TIGR00186 3 YLYGKNAVLEALLNQ---QRVFILKGLESKRLKKLIQLAKKQGINIQLVDRQKLDQLTkGGNHQGIAAKVKPILYKDLND 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 84 fLKQQKEKEGLSTVLILDGLEDPHNLGSILRTADATGVDGVIIPKRRSVTLTQTVAKASTGAIEHVPVIRVTNLAKTIDE 163
Cdd:TIGR00186 80 -LYKTAKSKKQPFLLILDEITDPHNLGAILRTAEAFGVDGVILPKRRSAPLNSTVVKTSSGAVEYVPLARVTNLSRTITK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 164 LKDNGFWVAGTEAN-NATDYRNLEaDMSLAIVIGSEGQGMSRLVSDKCDFYIKIPMVGHVNSLNASVAASLMMYEVFRKR 242
Cdd:TIGR00186 159 LKESGFWTVGTDLDaQDTLYQVKL-TKPLALVVGNEGEGVSRLIKENCDFLIKIPMAGKVDSLNVSVAAGILLFEIKRQR 237
|
|
| SpoU-like_RlmB |
cd18103 |
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the ... |
97-238 |
2.03e-81 |
|
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the methylation of guanosine 2251, a modification conserved in the peptidyltransferase domain of 23S rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349976 Cd Length: 143 Bit Score: 240.36 E-value: 2.03e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 97 VLILDGLEDPHNLGSILRTADATGVDGVIIPKRRSVTLTQTVAKASTGAIEHVPVIRVTNLAKTIDELKDNGFWVAGTEA 176
Cdd:cd18103 2 LLILDGITDPHNLGAIIRSAEAFGVDGVIIPKRRSAPLTPTVAKASAGALEHLPIARVTNLARALEELKEAGFWIYGADG 81
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 584759422 177 NNATDYRNLEADMSLAIVIGSEGQGMSRLVSDKCDFYIKIPMVGHVNSLNASVAASLMMYEV 238
Cdd:cd18103 82 EAEKSLYDVDLTGPLALVLGSEGKGLRRLVLKNCDFLVKIPMAGKVDSLNVSVAAGIILYEI 143
|
|
| PRK11181 |
PRK11181 |
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB; |
6-242 |
1.32e-67 |
|
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB;
Pssm-ID: 183021 [Multi-domain] Cd Length: 244 Bit Score: 209.05 E-value: 1.32e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 6 IVGRHAVrEAIITGHP--INKILIQEGIKKQQINEILKNAKDQKIIVQTVPKSKLDFLAN-APHQGVAALIAP---YEYA 79
Cdd:PRK11181 5 IYGIHAV-QALLERAPerFIEVFVLKGREDKRLLPLINELEAQGIVIQLANRQTLDEKAEgAVHQGIIARVKPgrqLQEN 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 80 DFDQFLkQQKEKEGLstvLILDGLEDPHNLGSILRTADATGVDGVIIPKRRSVTLTQTVAKASTGAIEHVPVIRVTNLAK 159
Cdd:PRK11181 84 DLPDLL-ASLEQPFL---LILDGVTDPHNLGACLRSADAAGVHAVIVPKDRSAQLNATAKKVACGAAETVPLIRVTNLAR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 160 TIDELKDNGFWVAGT--EANNaTDYrnlEADM--SLAIVIGSEGQGMSRLVSDKCDFYIKIPMVGHVNSLNASVAASLMM 235
Cdd:PRK11181 160 TMRMLQEKNIWIVGTagEADH-TLY---QSKLtgPLALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGICL 235
|
....*..
gi 584759422 236 YEVFRKR 242
Cdd:PRK11181 236 FEAVRQR 242
|
|
| SpoU_methylase |
pfam00588 |
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet. |
97-236 |
1.84e-53 |
|
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet.
Pssm-ID: 425768 Cd Length: 142 Bit Score: 169.25 E-value: 1.84e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 97 VLILDGLEDPHNLGSILRTADATGVDGVIIPKRRSVTL-TQTVAKASTGAIEHVPVIRVTNLAKTIDELKDNGFWVAGTE 175
Cdd:pfam00588 3 VVVLDNIQDPGNLGAIIRTAAAFGADGLILVEPRSADPyNPKAIRASAGALFHLPLVVVDNLEEALKDLKEAGYAVVATS 82
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 584759422 176 ANnATDYRNLEADMSLAIVIGSEGQGMSRLVSDKCDFYIKIPMVGHVNSLNASVAASLMMY 236
Cdd:pfam00588 83 LG-GKSLYEIDFPKKVALVFGNEGTGLSNEVLELCDRLVRIPMSGDVESLNVAVAAAIALY 142
|
|
| SpoU-like_rRNA-MTase |
cd18095 |
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
97-237 |
5.31e-53 |
|
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349968 Cd Length: 143 Bit Score: 167.99 E-value: 5.31e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 97 VLILDGLEDPHNLGSILRTADATGVDGVIIPKRRSVTLTQTVAKASTGAIEHVPVIRVTNLAKTIDELKDNGFWVAGTEA 176
Cdd:cd18095 2 VLVLDGVQDPGNLGTIIRTAAAFGVDGVILSKGTVDPYNPKVVRASMGALFRLPIIRVDDLEELLEELKEAGYKVVAADL 81
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 584759422 177 NNATDYRNLEADMSLAIVIGSEGQGMSRLVSDKCDFYIKIPMVGHVNSLNASVAASLMMYE 237
Cdd:cd18095 82 DGGSSLYDLDLPKPVALVLGNEGNGLSDELLELCDKRVTIPMSGGVESLNVAVAAAILLYE 142
|
|
| SpoU-like_MRM1 |
cd18105 |
SAM-dependent rRNA methylase related to MRM1; MRM1 catalyzes the methylation of 2'-O-ribose ... |
97-237 |
8.94e-45 |
|
SAM-dependent rRNA methylase related to MRM1; MRM1 catalyzes the methylation of 2'-O-ribose residues G1145 to GmG residue of the mitochondrial 16S rRNA. MRM1 is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349978 Cd Length: 158 Bit Score: 147.67 E-value: 8.94e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 97 VLILDGLEDPHNLGSILRTADATGVDGVIIPKRRSVTLTQTVAKASTGAIEHVPVIRVTNLAKTIDELKDNGFWVAGTEA 176
Cdd:cd18105 2 WLLLDEITDPQNLGAILRSAYFLGVDGVVVSSKNSAPLSPVVSKASAGALELMPIYSVDNLASFLKSSKENGWKVVGTSA 81
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 584759422 177 N----------NATDYRNLEADMSLAIVIGSEGQGMSRLVSDKCDFYIKIPM-----VGHVNSLNASVAASLMMYE 237
Cdd:cd18105 82 PpsassdkktiPANELSELLLEKPTILVLGNEGRGLRTNIKNLCDYLVSIPGgrsaeNPGVDSLNVSVAAGILLHS 157
|
|
| SpoU-like_RNA-MTase |
cd18104 |
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
97-242 |
1.75e-41 |
|
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349977 Cd Length: 146 Bit Score: 138.87 E-value: 1.75e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 97 VLILDGLEDPHNLGSILRTADATGVDGVIIPKRRSVTLTQTVAKASTGAIEHVPVIRVTNlAKTIDELKDNGFWVAGTEA 176
Cdd:cd18104 2 ILVLEGLEKPGNLGAILRSADAAGADAVILCDPKTDLFNPNVIRASLGAVFTLPVAEASS-EETLAWLKENKIRILATTP 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 584759422 177 NNATDYRNLEADMSLAIVIGSEGQGMSRLVSDKCDFYIKIPMVGHVNSLNASVAASLMMYEVFRKR 242
Cdd:cd18104 81 KAEKLYYEADLRGPIAIVVGSESEGLSEFWLKAADERVRIPMAGQADSLNVSVAAAILLYEALRQR 146
|
|
| SpoU-like_family |
cd18082 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
97-237 |
2.21e-34 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349955 Cd Length: 145 Bit Score: 120.41 E-value: 2.21e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 97 VLILDGLEDPHNLGSILRTADATGVDGVIIPKRRSVTLTQTVAKASTGAIEHVPVIRVTNLAKTIDELKDNGFWVAGTEA 176
Cdd:cd18082 1 HLVLDNIRSPGNIGSIFRTADAFGVEKIYLVGPTADIFDPKAKRTSRGTHFSVPYERVDNFEEYLKSLKEEGYPLIGLEL 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 584759422 177 NNA----TDYrNLEADMSLAIVIGSEGQGMSRLVSDKCDFYIKIPMVGHVNSLNASVAASLMMYE 237
Cdd:cd18082 81 TDGsiplSEF-KFKKPKKIALIFGNERSGLSPELLALCDYTVHIPMSGKNSSLNVSVATGIALYE 144
|
|
| SpoU-like_TrmH |
cd18092 |
SAM-dependent tRNA methylase related to TrmH; TrmH catalyzes the transfer of the methyl group ... |
97-242 |
1.27e-33 |
|
SAM-dependent tRNA methylase related to TrmH; TrmH catalyzes the transfer of the methyl group from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of the ribose of the universally conserved guanosine 18 (G18) position in tRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349965 Cd Length: 162 Bit Score: 119.11 E-value: 1.27e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 97 VLILDGLEDPHNLGSILRTADATGVDGV--IIPKRRsvtlTQTVAKASTGAIEHVPVIRVTNLAKTIDELKDNGFWVAGT 174
Cdd:cd18092 18 TVVLENVHDPHNASAVLRTCDAFGVQDVhvIEPKNK----FKKNRGVAMGADKWLDVHRHDSTEECLAALKEQGYRIVAT 93
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 584759422 175 E-ANNATDYRNLEADMSLAIVIGSEGQGMSRLVSDKCDFYIKIPMVGHVNSLNASVAASLMMYEVFRKR 242
Cdd:cd18092 94 SlSPDAVPLDELDYTRPTALVFGNEKDGVSEEALAAADERVYIPMYGFVESLNVSVAAAIILYELQRQR 162
|
|
| SpoU-like |
cd18097 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
97-238 |
1.80e-33 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349970 Cd Length: 144 Bit Score: 118.05 E-value: 1.80e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 97 VLILDGLEDPHNLGSILRTADATGVDGVIIPKRRSVTLTQTVAKASTGAIEHVPVIRVTNLAKTIDELKDNGFWVAGTE- 175
Cdd:cd18097 2 VVVLDNLRSAHNVGSIFRTADAAGVEKIYLCGYTPTPPHPKVAKTALGAEESVPWEHFEDTLEAVRALKARGYTIIALEt 81
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 584759422 176 ANNATDYRNLEADMSLAIVIGSEGQGMSRLVSDKCDFYIKIPMVGHVNSLNASVAASLMMYEV 238
Cdd:cd18097 82 TENSVPLHEARLPRPLALVLGNEVRGVSPEVLALCDAVVEIPMFGRKNSLNVAVAAAVALYEL 144
|
|
| PRK10864 |
PRK10864 |
putative methyltransferase; Provisional |
66-243 |
1.75e-25 |
|
putative methyltransferase; Provisional
Pssm-ID: 236779 [Multi-domain] Cd Length: 346 Bit Score: 102.16 E-value: 1.75e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 66 HQGVAALIAPYEYADFDQFLKQQKEKEglsTVLILDGLEDPHNLGSILRTADATGVDGVIIPkrrSVTLTQTVAKAST-- 143
Cdd:PRK10864 172 HGGVCFLIKKRNGTDVQQWLAQAGAQD---CVLALEDVGNPHNLGGIMRSCAHFGVKGVVVQ---DAALLESGAAIRTae 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 144 GAIEHVPVIRVTNLAKTIDELKDNGFWVAGTEANNATDYRNLEADMSLAIVIGSEGQGMSRLVSDKCDFYIKIPMVGHVN 223
Cdd:PRK10864 246 GGAEHVQPITGDSFVDVLDDFRQAGYTIVTTSSHKGTPLFKASLPAKMVLVLGQEYDGLSDAARQQGDLSVSIDGTGNVE 325
|
170 180
....*....|....*....|
gi 584759422 224 SLNASVAASLMMYEVFRKRH 243
Cdd:PRK10864 326 SLNVSVATGVLLAEWWRQNK 345
|
|
| SpoU-like_AviRb |
cd18107 |
SAM-dependent rRNA methylase related to AviRb; AviRb from Streptomyces viridochromogenes ... |
97-238 |
2.20e-25 |
|
SAM-dependent rRNA methylase related to AviRb; AviRb from Streptomyces viridochromogenes methylates the 2'-O atom of U2479 of the 23S ribosomal RNA. AviRb is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349980 Cd Length: 148 Bit Score: 97.46 E-value: 2.20e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 97 VLILDGLEDPHNLGSILRTADATGVDGVIIPKRRSVTLTQTVAKASTGAIEHVPVIRVTNLAKTIDELKD-----NGFWV 171
Cdd:cd18107 2 VVLFDRPTSPGNLGTIIRSADALGAHGLVVTGHAADVYDPKTIRASTGSLFSLPIVRVPSNRELEDWVEArkargTPLQL 81
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 584759422 172 AGTEanNATDYRNLEADMS--LAIVIGSEGQGMSRLVSDKCDFYIKIPMVGHVNSLNASVAASLMMYEV 238
Cdd:cd18107 82 VGTD--EHGDHQIADHDFTrpTLLLIGNETAGLSAAWRELCDETVSIPMAGSASSLNAACAASIFLYEA 148
|
|
| PRK11081 |
PRK11081 |
tRNA guanosine-2'-O-methyltransferase; Provisional |
100-246 |
2.94e-22 |
|
tRNA guanosine-2'-O-methyltransferase; Provisional
Pssm-ID: 236837 [Multi-domain] Cd Length: 229 Bit Score: 91.21 E-value: 2.94e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 100 LDGLEDPHNLGSILRTADATGVDGV--IIPKRRsvtlTQTVAKASTGAIEHVPVIRVTNLAKTIDELKDNGFWVAGTE-A 176
Cdd:PRK11081 24 MEQVHKPHNVSAIIRTADAVGVHEVhaVWPGSR----MRTMGSTAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHlS 99
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 177 NNATDYRNLEADMSLAIVIGSEGQGMSRLVSDKCDFYIKIPMVGHVNSLNASVAASLMMYEVFRKRHDVG 246
Cdd:PRK11081 100 DTAVDFREIDYTRPTCILMGQEKTGISQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQRQNAG 169
|
|
| SpoU-like_RNA-MTase |
cd18109 |
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
97-237 |
4.71e-22 |
|
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349982 Cd Length: 141 Bit Score: 88.36 E-value: 4.71e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 97 VLILDGLEDPHNLGSILRTADATGVDGVII---------PKrrsvtltqtVAKASTGAIEHVPVIRvTNLAKTIDELKDN 167
Cdd:cd18109 2 TLALDGIQDPGNLGTIIRTADWFGIRQIICspdtvdpynPK---------VVQASMGSIFRVQIHY-TDLPALLAELKKA 71
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 584759422 168 GFwVAGTEAnNATDYRNLEADMSLAIVIGSEGQGMSRLVSDKCDFYIKIPMVG-HVNSLNASVAASLMMYE 237
Cdd:cd18109 72 FP-VYGADL-DGENLYEFTLPEKGILVMGNEGHGISPEVLKLLTHRLTIPRYGkGAESLNVAVATAILLSE 140
|
|
| SpoU_sub_bind |
pfam08032 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
5-77 |
3.09e-20 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 429793 [Multi-domain] Cd Length: 74 Bit Score: 81.52 E-value: 3.09e-20
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 584759422 5 VIVGRHAVREAIITGHPINKILIQEGIKKQQINEILKNAKDQKIIVQTVPKSKLDFLA-NAPHQGVAALIAPYE 77
Cdd:pfam08032 1 LIYGRHAVLEALKSGPEIKKLYLTEGRRDPRLKELLKLAKERGIKVEEVDRKKLDKLSgTANHQGVVAEVKPYE 74
|
|
| SpoU-like_TRM3-like |
cd18091 |
SAM-dependent tRNA methylase related to TRM3; Yeast tRNA (guanosine(18)-2'-O) ... |
103-237 |
1.04e-17 |
|
SAM-dependent tRNA methylase related to TRM3; Yeast tRNA (guanosine(18)-2'-O)-methyltransferase TRM3 catalyzes the formation of 2'-O-methylguanosine at position 18 (Gm18) in various tRNAs. TRM3 is similar to C-terminal domain of TAR (HIV-1) RNA binding protein 1 (TARBP1), a protein binding to TAR, which functions as a RNA regulatory signal by forming a stable stem-loop structure to which transactivator protein Tat binds. The role of TARBP1 is believed to be to disengage RNA polymerase II from TAR during transcriptional elongation. TRM3 and the C-terminal methyltransferase domain of TARBP1 are members of the SPOUT methyltransferase superfamily.
Pssm-ID: 349964 Cd Length: 145 Bit Score: 77.19 E-value: 1.04e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 103 LEDPHNLGSILRTADATGVDGVIIPKRRSVTLTQTVAKASTGAiEHVPV--IRVTNLAKTIDELKDNGFWVAGTE-ANNA 179
Cdd:cd18091 8 IDKPPNLGGLCRTCEIFGVSKLVLPNLAVVEDKQFKALSVSAE-KWLPIeeVKPEDLLPYLKEKKQEGYTIVGLEqTANS 86
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 584759422 180 TDYRNLEADMSLAIVIGSEGQGMSRLVSDKCDFYIKIPMVGHVNSLNASVAASLMMYE 237
Cdd:cd18091 87 VSLHDFQFPKKTVLVLGNEKEGIPAELLSLLDVCVEIPQLGVIRSLNVHVSGAIAIYE 144
|
|
| SpoU-like_RNMTL1 |
cd18106 |
SAM-dependent rRNA methylase related to RNMTL1; RNMTL1 (also known as HC90, MRM3 and RMTL1) ... |
98-237 |
5.07e-17 |
|
SAM-dependent rRNA methylase related to RNMTL1; RNMTL1 (also known as HC90, MRM3 and RMTL1) catalyzes the methylation of 2'-O-ribose residues G1370 to GmG residue of the mitochondrial 16S rRNA. RNMTL1 is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349979 Cd Length: 148 Bit Score: 75.37 E-value: 5.07e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 98 LILDGLEDPHNLGSILRTADATGVDGVIIPKrRSVTLTQT-VAKASTGAIEHVPVIrvTNL-AKTIDELKDNGFWVAGTE 175
Cdd:cd18106 3 VICDNIRDPGNLGSILRSAAAAGCSKVLLTK-GCVDPWEPkVLRAGAGAHFRLPIY--GNLsWDDIPNYLPDDSKVFLAD 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 584759422 176 ANNAT-DYRNLEADM-SLAIVIGSEGQGMS----RLVSDKCDFYIKIPMVGHVNSLNASVAASLMMYE 237
Cdd:cd18106 80 NNLPVqPYDSIDYCSgPIVLVIGGETHGVSpeayKLAHSTGGSRVHIPLANGVDSLNSAVAASILLFE 147
|
|
| SpoU-like |
cd18096 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
96-237 |
8.99e-17 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349969 Cd Length: 140 Bit Score: 74.56 E-value: 8.99e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 96 TVLILDGLEDPHNLGSILRTADATGVDGVIIPKRRSVTLTqtvakASTGAIEHVPVIRVTNLAKTIDELKDNGFWVAGTE 175
Cdd:cd18096 1 LYLVLHNVAKRHNIGTIVRSANAFGVKEVHLVGRRKFNPF-----GAMGTDRHVKFRHFDTLAEAKEYLKERGIRLVGVE 75
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 584759422 176 anNATDYRNLEADM---SLAIVIGSEGQGMSRLVSDKCDFYIKIPMVG-HVNSLNASVAASLMMYE 237
Cdd:cd18096 76 --IVPGAEPIETHPfpgDTAFVLGNEGTGLSDEQLAICDGFVYIPQYGsGTASLNVSVAASIVLHH 139
|
|
| SpoU_sub_bind |
smart00967 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
6-75 |
7.16e-16 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 214943 [Multi-domain] Cd Length: 70 Bit Score: 69.87 E-value: 7.16e-16
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 584759422 6 IVGRHAVREAIITGHPINKILIQEGIKKqQINEILKNAKDQKIIVQTVPKSKLDFLA-NAPHQGVAALIAP 75
Cdd:smart00967 1 IEGRHAVEEALKSGRRIKELYLTEGRAE-RLKELLKLAKERGIKVIEVSKKELDKLSgTANHQGVVAVVKP 70
|
|
| SpoU-like_NHR |
cd18108 |
Nosiheptide-resistance methyltransferase (NHR); Nosiheptide-resistance methyltransferase (NHR) ... |
97-237 |
3.44e-14 |
|
Nosiheptide-resistance methyltransferase (NHR); Nosiheptide-resistance methyltransferase (NHR) confers resistance to the thiazole antibiotic nosiheptide via catalyzing 2'O-methylation of 23S rRNA at the nucleotide A1067. NHR is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349981 Cd Length: 144 Bit Score: 67.50 E-value: 3.44e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 97 VLILDGLEDPHNLGSILRTADATGVDGVIIPKRRSVTLT-QTVAKASTGAIEHVPVIrVTNLAKTIDELKDNGFWVAGTE 175
Cdd:cd18108 2 VVVLDGVRIVGNIGAIVRTSLALGAAGIVLVDSDLATVAdRRLLRASRGYVFSLPVV-LADREEAVAFLRDNDIPLMTLD 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 584759422 176 ANNATDYRNLEADMS-LAIVIGSEGQGMSRLVSDKCDFYIKIPMVGHVNSLNASVAASLMMYE 237
Cdd:cd18108 81 ADGDVPVKELGDRPDrLALVFGSEKGGPSGLFEEAAAGTVSIPMSSSTESLNVSVSAGIALHE 143
|
|
| SpoU-like |
cd18098 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
102-236 |
8.74e-10 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349971 Cd Length: 138 Bit Score: 55.35 E-value: 8.74e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 102 GLE---DPHNLGSILRTADATGVDGVI-IPKR----RSVTLTQTVAKastgaieHVPVIRVTNLAKTIDELKDNGFWVA- 172
Cdd:cd18098 4 GIEnpkTPKNVGTLWRAAGCLGASFVFtIGARykrrKQSTDTSKAWR-------HIPLFHYDDLEDLAEPLPFGAVLVAv 76
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 584759422 173 --GTEANNATDYRNLEadmsLAI-VIGSEGQGMSRLVSDKCDFYIKIPMVGhvnSLNASVAASLMMY 236
Cdd:cd18098 77 elTEGATPLPDFKHPD----RAVyLLGPEDGGLPQEVLARCHHVVYLPTRG---SLNVAVAGSIVLY 136
|
|
| SpoU-like_TrmL |
cd18094 |
SAM-dependent tRNA methylase related to TrmL; tRNA (Um34/Cm34) methyltransferase TrmL ... |
104-240 |
5.82e-09 |
|
SAM-dependent tRNA methylase related to TrmL; tRNA (Um34/Cm34) methyltransferase TrmL catalyzes the methyl transfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH at position 34 in both tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349967 Cd Length: 145 Bit Score: 53.23 E-value: 5.82e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 104 EDPHNLGSILRTADATGVDGVIIpKRRSVTLTQ-TVAKASTGAIEHVPVIRVTNLAKTIDELKDNGFWVAGTEANNA--- 179
Cdd:cd18094 8 EIPQNTGNIARTCAATGARLHLI-EPLGFSLDDkRLKRAGLDYWDHVDLTVHDSWEAFLEALPPGRLFLFTTKGTKPytd 86
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 584759422 180 TDYRNleadmSLAIVIGSEGQGMSRLVSDKC-DFYIKIPMVGHVNSLNASVAASLMMYEVFR 240
Cdd:cd18094 87 FDFKP-----GDYLVFGRESTGLPEEILDAFpDRRLRIPMRPKVRSLNLSNSVAIVLYEALR 143
|
|
| TrmL |
COG0219 |
tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain [Translation, ... |
106-240 |
3.35e-07 |
|
tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain [Translation, ribosomal structure and biogenesis]; tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 439989 Cd Length: 153 Bit Score: 48.49 E-value: 3.35e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 106 PHNLGSILRTADATGVDGVII-P----------KRrsvtltqtvakASTGAIEHVPVIRVTNLAKTIDELKDNGFWVAGT 174
Cdd:COG0219 12 PQNTGNIIRLCAATGARLHLIePlgfslddkklKR-----------AGLDYWELVDLTVHDSWEAFLEALPGGRLFLFTT 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 584759422 175 EANNA-TDYRNLEADmslAIVIGSEGQGMSR-LVSDKCDFYIKIPMVGHVNSLNASVAASLMMYEVFR 240
Cdd:COG0219 81 KGTKPyTDVDYQPGD---VLLFGRETAGLPEeVLAAPADQRLRIPMRPGVRSLNLSNAVAIVLYEALR 145
|
|
| rRNA_methyl_1 |
TIGR00050 |
RNA methyltransferase, TrmH family, group 1; This is part of the trmH (spoU) family of ... |
92-242 |
1.11e-06 |
|
RNA methyltransferase, TrmH family, group 1; This is part of the trmH (spoU) family of S-adenosyl-L-methionine (AdoMet)-dependent methyltransferases, and is now characterized, in E. coli, as a tRNA:Cm32/Um32 methyltransferase. It may be named TrMet(Xm32), or TrmJ, according to the nomenclature style chosen [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 272876 [Multi-domain] Cd Length: 233 Bit Score: 48.16 E-value: 1.11e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 92 EGLSTVLIldGLEDPHNLGSILRTADATGVDGVIIPKRRSVTLTQTVAKAStGAIEHVPVIRVTNlakTIDELKDNGFWV 171
Cdd:TIGR00050 2 ENIRIVLV--EPSHPGNIGSIARAMKNMGLTELRLVNPRVKLEEEAYALAA-GARDILDNAKVVD---TLDEALDDCDFV 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 172 AGTEANNATDYRNLEADMSL-----------AIVIGSEGQGMSRLVSDKCDFYIKIPMVGHVNSLNASVAASLMMYEVFR 240
Cdd:TIGR00050 76 VGTSARSRNLQRPMLTPRELapklvaekgkvALVFGREDSGLTNEELQKCHVLVSIPTSEEYPSLNLSHAVAVILYELRM 155
|
..
gi 584759422 241 KR 242
Cdd:TIGR00050 156 AW 157
|
|
| SpoU-like_TrmJ |
cd18093 |
SAM-dependent tRNA methylase related to TrmJ; tRNA methyltransferase TrmJ catalyzes the methyl ... |
99-237 |
4.12e-05 |
|
SAM-dependent tRNA methylase related to TrmJ; tRNA methyltransferase TrmJ catalyzes the methyl transfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH at position 32 in both tRNASer1 and tRNAGln2. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349966 Cd Length: 153 Bit Score: 42.48 E-value: 4.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584759422 99 ILDGLEDPHNLGSILRTADATGVDGVIIPKRRSVTLTQTVAKASTGA---IEHVPVirVTNLAktiDELKDNGFWVA--- 172
Cdd:cd18093 4 VLVEPQHPGNIGAVARAMKNFGLSDLRLVNPRCDDPEEAARALASGAedvLENAKV--YDTLE---EALADCDLVVAtta 78
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 584759422 173 --GTEANNATDYRNLEADMS-------LAIVIGSEGQGMSR--LvsDKCDFYIKIPMVGHVNSLNASVAASLMMYE 237
Cdd:cd18093 79 rpRGLRRPLLTPRELAELLKehaaggkVALVFGREDSGLTNeeL--ALCDLLVTIPTNPEYPSLNLAQAVAIVLYE 152
|
|
| TrmJ |
COG0565 |
tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase [Translation, ... |
192-244 |
2.28e-03 |
|
tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase [Translation, ribosomal structure and biogenesis]; tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440331 [Multi-domain] Cd Length: 237 Bit Score: 38.17 E-value: 2.28e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 584759422 192 AIVIGSEGQGMSR--LvsDKCDFYIKIPmvghVN----SLNASVAASLMMYEVFRKRHD 244
Cdd:COG0565 109 ALVFGRERSGLTNeeL--ALCDALVTIP----TNpeypSLNLAQAVQVVAYELRKAALE 161
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