|
Name |
Accession |
Description |
Interval |
E-value |
| pheT |
PRK00629 |
phenylalanyl-tRNA synthetase subunit beta; Reviewed |
1-800 |
0e+00 |
|
phenylalanyl-tRNA synthetase subunit beta; Reviewed
Pssm-ID: 234804 [Multi-domain] Cd Length: 791 Bit Score: 1053.23 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 1 MLISNEWLKEYVTIDDSVSNLAERITRTGIEVDDLIDYTKDIKNLVVGFVKSKEKHPDADKLNVCQVDIGEdEPVQIVCG 80
Cdd:PRK00629 1 MKFSLSWLKEYVNPDISSEELAEALTMIGLEVEGVEDVAAGLSGVVVGKVLECEKHPNADKLRVCQVDVGE-EPLQIVCG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 81 APNVDAGQYVIVAKVGGRLPGGIKIKRAKLRGERSEGMICSLQEIGISSNyipksfESGIYVFSEAQVPGTDALQALYLD 160
Cdd:PRK00629 80 APNVRAGDKVPVALPGAVLPGGFKIKKAKLRGVESEGMLCSASELGLSDD------HDGIIELPEDAPVGTDAREYLGLD 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 161 DQVMEFDLTPNRADALSMIGTAYEVAALYNTKMTKPETTSNELDlsANDELTVTIENEDKVPYYSARVVHDVT-IEPSPI 239
Cdd:PRK00629 154 DTVIEISLTPNRADCLSVRGIARELAALLGLPLKLPEIEPVPAT--IDDKLPVEIEDPDLCPRYAGRVIKGVKnIAPSPL 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 240 WMQARLIKAGIRPINNVVDISNYVLLEYGQPLHMFDQDAIGsQQIVVRQANEGEKMTTLDDTERELLTSDIVITNGQTPI 319
Cdd:PRK00629 232 WLQERLRAAGIRPINNVVDITNYVMLELGQPLHAFDLDKIG-GGIVVRRAKEGEKLTTLDGKERTLDPEDLVIADDKKPL 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 320 ALAGVMGGDFSEVKEQTSNIVIEGAIFDPVSIRHTSRRLNLRSESSSRFEKGIATEFVDEAVDRACYLLQTYANGKVLKD 399
Cdd:PRK00629 311 ALAGVMGGEDSEVTENTTNVLLESAYFDPVSIRKTARRLGLRTDASYRFERGVDPALTLLALERATALILELGGGEVVEG 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 400 RVSSGELgAFITPIDITADKINRTIGFDLSQNDIVTIFNQLGFD-TEINDDVITVLVPSRRKDITIKEDLIEEVARIYGY 478
Cdd:PRK00629 391 VVDVYPL-PKEPTITLRLERINRLLGTEISDEEIVDILKRLGFEvTEVDGDGLTVTVPSWRFDIEIEEDLVEEVARIYGY 469
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 479 DDIPSTLPVfDKVTSGQLTDRQYKTRMVKEVLEGAGLDQAITYSLVSKEDATAFSMQQrQTIDLLMPMSEAHASLRQSLL 558
Cdd:PRK00629 470 DNIPSTPPV-AALTMGGLTEAQRLLRRLRRALAALGYQEVITYSFVSPEDAKLFGLNP-EPLLLLNPISEELSVMRTSLL 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 559 PHLIEAASYNVARKNKDVKLFEIGNVFfaNGEGELPDQVEYLSGILTGDYVVNQWQDKKEtVDFYLAKGVVDRVSEKLNL 638
Cdd:PRK00629 548 PGLLEAVAYNLNRGNKDVALFEIGRVF--LPDGDLPREPEHLAGVLTGNRVEESWGGKRP-VDFFDLKGDVEALLEALGL 624
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 639 EFS--YRRADIDGLHPGRTAEILLENKVVGFIGELHPILAADNDLK-RTYVFELNFDALMAVSVGYINYQPIPRFPGMSR 715
Cdd:PRK00629 625 PEVefVAEFEAAALHPGRSAEIYLDGKVIGFIGELHPKVLKKLDLPgRTYVFELDLDALLEAARKLPKYKPISKFPAVRR 704
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 716 DIALEVDQNIPAADLLSTIHAHGGNILKDTLVFDVYQGEHLEKGKKSIAIRLNYLDTEETLTDERVSKVQAEIEAALIEQ 795
Cdd:PRK00629 705 DLALVVDEDVPAADILKAIKKAGGKLLESVELFDVYEGKGIGEGKKSLAFRLTFQDPDRTLTDEEINAAMDKIVAALEEK 784
|
....*.
gi 584942020 796 -GAVIR 800
Cdd:PRK00629 785 fGAELR 790
|
|
| PheT |
COG0072 |
Phenylalanyl-tRNA synthetase beta subunit [Translation, ribosomal structure and biogenesis]; ... |
1-800 |
0e+00 |
|
Phenylalanyl-tRNA synthetase beta subunit [Translation, ribosomal structure and biogenesis]; Phenylalanyl-tRNA synthetase beta subunit is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439842 [Multi-domain] Cd Length: 793 Bit Score: 978.88 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 1 MLISNEWLKEYVTIDDSVSNLAERITRTGIEVDDLIDYTKDIKNLVVGFVKSKEKHPDADKLNVCQVDIGEDEPVQIVCG 80
Cdd:COG0072 1 MKLSLLWLLLLVEEAALLEELLLLLTGEGLEEEEVEGAAAVVVGVVVVVVVVEEPHPDADDLVVVVVDVGGGEVLVVVCG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 81 APNVDAGQYVIVAKVGGRLPGGIKIKRAKLRGERSEGMICSLQEIGISSNyipksfESGIYVFSEAQVPGTDALQALYLD 160
Cdd:COG0072 81 AANVAVGVVVVAAPGGAVLPGGFKIKKAKIRGVESSGMLCSEEELGLGED------HDGIIVLPPDAPVGGDAREYLGLD 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 161 DQVMEFDLTPNRADALSMIGTAYEVAALYNTKMTKPETtSNELDLSANDELTVTIENEDKVPYYSARVVHDVTIEPSPIW 240
Cdd:COG0072 155 DTVLEIDLTPNRADCLSVRGVARELAALLGAPLKLPAI-EPEVPPAIDDPIPVEIEDPEACPRYAGRVIRGVKVGPSPLW 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 241 MQARLIKAGIRPINNVVDISNYVLLEYGQPLHMFDQDAIGSQqIVVRQANEGEKMTTLDDTERELLTSDIVITNGQTPIA 320
Cdd:COG0072 234 MQERLRAAGIRPINNVVDITNYVMLELGQPLHAFDLDKLKGG-IVVRRAREGEKLTTLDGKERTLDPDDLVIADDEGPLA 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 321 LAGVMGGDFSEVKEQTSNIVIEGAIFDPVSIRHTSRRLNLRSESSSRFEKGIATEFVDEAVDRACYLLQTYANGKVLKDR 400
Cdd:COG0072 313 LAGVMGGEDSEVTEETTDVLLESAYFDPVSIRRTARRLGLHSDASYRFERGVDPALTVAALERATQLILEIAGGEVGPGI 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 401 VSSGELGAFITPIDITADKINRTIGFDLSQNDIVTIFNQLGFDTEINDDVITVLVPSRRKDITIKEDLIEEVARIYGYDD 480
Cdd:COG0072 393 VDVYPEPPEPKTITLRLARINRLLGVEIPAEEIEEILERLGFEVEEDGDGLTVTVPSWRFDIEIEADLIEEVARIYGYDN 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 481 IPSTLPVFDkVTSGQLTDRQYKTRMVKEVLEGAGLDQAITYSLVSKEDATAFSMqQRQTIDLLMPMSEAHASLRQSLLPH 560
Cdd:COG0072 473 IPSTLPRAP-LAGGGLTEAQRLRRRVRRALAARGYQEVITYSFVSPEDADLFGL-RREAVRLANPISEDLSVMRTSLLPG 550
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 561 LIEAASYNVARKNKDVKLFEIGNVFFANGEGElPDQVEYLSGILTGDYVVNQWQDKKETVDFYLAKGVVDRVSEKLNLE- 639
Cdd:COG0072 551 LLEAAAYNLNRGQKDVRLFEIGRVFLPDEGEE-PREPLHLAGVLTGNREPESWGGKARPVDFFDLKGDVEALLAALGVPk 629
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 640 FSYRRADIDGLHPGRTAEILLENKVVGFIGELHPILAADNDLK-RTYVFELNFDALMAVSVGYINYQPIPRFPGMSRDIA 718
Cdd:COG0072 630 LEFEAAEHPALHPGRSAEILLGGKVIGFIGELHPKVLKALDLPgPVYVFELDLDALLELARKVPKYKPISKFPAVRRDLA 709
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 719 LEVDQNIPAADLLSTIHAHGGNILKDTLVFDVYQGEHLEKGKKSIAIRLNYLDTEETLTDERVSKVQAEIEAALIEQ-GA 797
Cdd:COG0072 710 LVVDEDVPAADVLDAIRKAAGKLLEDVRLFDVYEGKGVPEGKKSLAFSLTLQDPDRTLTDEEIDAAMDKIVAALEKKfGA 789
|
...
gi 584942020 798 VIR 800
Cdd:COG0072 790 ELR 792
|
|
| pheT_bact |
TIGR00472 |
phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial; Every known example of ... |
1-800 |
0e+00 |
|
phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial; Every known example of the phenylalanyl-tRNA synthetase, except the monomeric form of mitochondrial, is an alpha 2 beta 2 heterotetramer. The beta subunits break into two subfamilies that are considerably different in sequence, length, and pattern of gaps. This model represents the subfamily that includes the beta subunit from Bacteria other than spirochetes, as well as a chloroplast-encoded form from Porphyra purpurea. The chloroplast-derived sequence is considerably shorter at the amino end. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273097 [Multi-domain] Cd Length: 797 Bit Score: 815.37 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 1 MLISNEWLKEYVTIDDSVSN-LAERITRTGIEVDDLIDYTKDIKNLVVGFVKSKEKHPDADKLNVCQVDIGEDEPVQIVC 79
Cdd:TIGR00472 1 MKISLKWLREYVPLSEIDNEeIAEALTSIGLEVEAVIPFSKPLKGVVVGKVLEVEPHPNADKLKVCKVDIGEKEMLQIVC 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 80 GAPNVDAGQYVIVAKVGGRLPGGIKIKRAKLRGERSEGMICSLQEIGISSNyipksfESGIYVFSEAQVPGTDALQALYL 159
Cdd:TIGR00472 81 GAPNVEAGKKVAVALPGAKLPNGLKIKKSKLRGVESEGMLCSESELGLDEK------SDGIIVLDEDAPLGTDIAEYLGL 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 160 DDQVMEFDLTPNRADALSMIGTAYEVAALYNTKMTKPETTSNELDLSANDELTVTIENEDKVPYYSARVVHDVTIEPSPI 239
Cdd:TIGR00472 155 DDDIIEVSITPNRGDCLSILGIARELAALFDLNLETPVPFEPETTETIDEGFKIEIEDPEVCPFYLGRVIKGVKVKPSPL 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 240 WMQARLIKAGIRPINNVVDISNYVLLEYGQPLHMFDQDAIgSQQIVVRQANEGEKMTTLDDTERELLTSDIVITNGQTPI 319
Cdd:TIGR00472 235 WLKERLRRSGIRPINNIVDITNYVMLELGQPLHAFDADKI-EGNIVVRSAKEGESFTTLDGKERELKKGDLVIADDKKPL 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 320 ALAGVMGGDFSEVKEQTSNIVIEGAIFDPVSIRHTSRRLNLRSESSSRFEKGIATEFVDEAVDRACYLLQTYANGKVLKD 399
Cdd:TIGR00472 314 AIAGVMGGKESGVTDTTTNIFLESAYFNPESIRKTARRLGISTDSSYRFERGVDPELTELALDRALNLILEIFGGEVISV 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 400 RVSSGELGAFITPIDITADKINRTIGFDLSQNDIVTIFNQLGFDTEINDDVITVLVPSRRKDITIKEDLIEEVARIYGYD 479
Cdd:TIGR00472 394 VSDNYKEKAKEKKISLRIKKLNKILGIELSDEEVRDILKRLGFKVEKQKDGWEVTVPSYRHDIEIEEDLIEEIARIYGYD 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 480 DIPSTLPVFDKVTSGQLTDRQYKTRmVKEVLEGAGLDQAITYSLVSKEDATAFSMQQR-QTIDLLMPMSEAHASLRQSLL 558
Cdd:TIGR00472 474 NIPAEPLSVSSKLNKNNENYLLLRK-LRTLLVGLGLNEVITYSFVDPEKAEKFNFPKLeNLVEIKNPLSNERSVLRTSLL 552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 559 PHLIEAASYNVARKNKDVKLFEIGNVFFANGEGELpdQVEYLSGILTGDYVVNQWQDKKETVDFYLAKGVVDRVSEKLNL 638
Cdd:TIGR00472 553 PSLLEVLAYNQNRKNKDVKIFEIGKVFAKDGEAVK--EQLRLAILISGEKNPSSWNHKEEKVDFYDLKGDVESLLELLGL 630
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 639 --EFSYRR-ADIDGLHPGRTAEILLENKVVGFIGELHPILAADNDLK-RTYVFELNFDALMAVSVGYINYQPIPRFPGMS 714
Cdd:TIGR00472 631 sdDVYFKNtAENEELHPGQSATIYLKGKKIGFIGELHPEIAKKYDLKePTFVFELDLDRLLESLKKVPKYRPISKFPAVT 710
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 715 RDIALEVDQNIPAADLLSTIHAHGGNILKDTLVFDVYQGEHLEKGKKSIAIRLNYLDTEETLTDERVSKVQAEIEAALIE 794
Cdd:TIGR00472 711 RDISFLVPKDVPANEIIKLIKKSGLELLEEVELFDVYQGKNIGEGKKSLALRLVLRDKERTLTDEEINKIVEKVLNALKE 790
|
....*..
gi 584942020 795 Q-GAVIR 800
Cdd:TIGR00472 791 KlGAELR 797
|
|
| tRNA_synthFbeta |
pfam17759 |
Phenylalanyl tRNA synthetase beta chain CLM domain; This domain corresponds to the catalytic ... |
481-691 |
3.02e-86 |
|
Phenylalanyl tRNA synthetase beta chain CLM domain; This domain corresponds to the catalytic like domain (CLM) in the beta chain of phe tRNA synthetase.
Pssm-ID: 465487 [Multi-domain] Cd Length: 214 Bit Score: 272.12 E-value: 3.02e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 481 IPSTLPVFDkVTSGQLTDRQYKTRMVKEVLEGAGLDQAITYSLVSKEDATAF--SMQQRQTIDLLMPMSEAHASLRQSLL 558
Cdd:pfam17759 1 IPSTLPKGP-TTGGGLTPEQKLRRRVRDLLAAAGFTEVITYSFTSPKDLDKLleDDPRRKAVKLANPLSEELSVMRTSLL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 559 PHLIEAASYNVARKNKDVKLFEIGNVFFANGEGELPDQVEYLSGILTGDYVVNQWQDKKETVDFYLAKGVVDRVSEKLNL 638
Cdd:pfam17759 80 PGLLETLAYNLNRGNPDVRLFEIGRVFLPDELEELPREPRRLAGLLTGKRLPESWQGKARPVDFYDLKGIVEALLAALGI 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 584942020 639 -EFSYRRADIDGLHPGRTAEILLENKVVGFIGELHPILAADNDLK-RTYVFELNF 691
Cdd:pfam17759 160 dDYEFEAADHPALHPGRSAEILVGGKVIGFIGELHPEVAKNFDLPqPVYVFELDL 214
|
|
| B3_4 |
smart00873 |
B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA ... |
222-392 |
1.03e-67 |
|
B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA synthetase proteins.
Pssm-ID: 214876 [Multi-domain] Cd Length: 174 Bit Score: 221.75 E-value: 1.03e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 222 PYYSARVVHDVTIE-PSPIWMQARLIKAGIRPINNVVDISNYVLLEYGQPLHMFDQDAIGSQQIVVRQANEGEKMTTLDD 300
Cdd:smart00873 2 PRYLGRVIRGVKNTrPSPEWLQERLHRAGIRPINNVVDITNYVSLETGQPLHAFDLDKIKGKDIPLRRAKEGEKFETLDG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 301 TERELLTSDIVITNGQTPIALAGVMGGDFSEVKEQTSNIVIEGAIFDPVSIRHTSRRLNLRSESSSRFEKGIATEFVDEA 380
Cdd:smart00873 82 KEYELDEGDLVIADDEGPLALAGVMGGEESEVTENTTVIFLEPAIFSPRTIRITARTLNLFTDASGRFERGVDPELVELA 161
|
170
....*....|..
gi 584942020 381 VDRACYLLQTYA 392
Cdd:smart00873 162 LDRAAALLLEIC 173
|
|
| PheRS_beta_core |
cd00769 |
Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II ... |
503-694 |
1.13e-66 |
|
Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA, PheRS is an exception in that it attaches the amino acid at the 2'-OH group, like class I aaRSs. PheRS is an alpha-2/ beta-2 tetramer. While the alpha chain contains a catalytic core domain, the beta chain has a non-catalytic core domain.
Pssm-ID: 238392 [Multi-domain] Cd Length: 198 Bit Score: 219.82 E-value: 1.13e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 503 TRMVKEVLEGAGLDQAITYSLVSKEDATAFSMQQRQTIDLLMPMSEAHASLRQSLLPHLIEAASYNVARKNKDVKLFEIG 582
Cdd:cd00769 6 ERKLRRLLAGLGFQEVITYSLTSPEEAELFDGGLDEAVELSNPLSEEYSVLRTSLLPGLLDALARNLNRKNKPLRLFEIG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 583 NVFFANGEGelPDQVEYLSGILTGDYVVNQWQDKKETVDFYLAKGVVDRVSEKLN--LEFSYRRADIDGLHPGRTAEILL 660
Cdd:cd00769 86 RVFLKDEDG--PEEEEHLAALLSGNREPESWQGKGRPVDFYDAKGILEALLRALGiiVEFELEELDADLFHPGRSAKIYV 163
|
170 180 190
....*....|....*....|....*....|....*
gi 584942020 661 ENKVVGFIGELHPILAADNDLK-RTYVFELNFDAL 694
Cdd:cd00769 164 NGEVIGFIGELHPEVLKEFDLKePVYAFELDLDAL 198
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| pheT |
PRK00629 |
phenylalanyl-tRNA synthetase subunit beta; Reviewed |
1-800 |
0e+00 |
|
phenylalanyl-tRNA synthetase subunit beta; Reviewed
Pssm-ID: 234804 [Multi-domain] Cd Length: 791 Bit Score: 1053.23 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 1 MLISNEWLKEYVTIDDSVSNLAERITRTGIEVDDLIDYTKDIKNLVVGFVKSKEKHPDADKLNVCQVDIGEdEPVQIVCG 80
Cdd:PRK00629 1 MKFSLSWLKEYVNPDISSEELAEALTMIGLEVEGVEDVAAGLSGVVVGKVLECEKHPNADKLRVCQVDVGE-EPLQIVCG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 81 APNVDAGQYVIVAKVGGRLPGGIKIKRAKLRGERSEGMICSLQEIGISSNyipksfESGIYVFSEAQVPGTDALQALYLD 160
Cdd:PRK00629 80 APNVRAGDKVPVALPGAVLPGGFKIKKAKLRGVESEGMLCSASELGLSDD------HDGIIELPEDAPVGTDAREYLGLD 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 161 DQVMEFDLTPNRADALSMIGTAYEVAALYNTKMTKPETTSNELDlsANDELTVTIENEDKVPYYSARVVHDVT-IEPSPI 239
Cdd:PRK00629 154 DTVIEISLTPNRADCLSVRGIARELAALLGLPLKLPEIEPVPAT--IDDKLPVEIEDPDLCPRYAGRVIKGVKnIAPSPL 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 240 WMQARLIKAGIRPINNVVDISNYVLLEYGQPLHMFDQDAIGsQQIVVRQANEGEKMTTLDDTERELLTSDIVITNGQTPI 319
Cdd:PRK00629 232 WLQERLRAAGIRPINNVVDITNYVMLELGQPLHAFDLDKIG-GGIVVRRAKEGEKLTTLDGKERTLDPEDLVIADDKKPL 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 320 ALAGVMGGDFSEVKEQTSNIVIEGAIFDPVSIRHTSRRLNLRSESSSRFEKGIATEFVDEAVDRACYLLQTYANGKVLKD 399
Cdd:PRK00629 311 ALAGVMGGEDSEVTENTTNVLLESAYFDPVSIRKTARRLGLRTDASYRFERGVDPALTLLALERATALILELGGGEVVEG 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 400 RVSSGELgAFITPIDITADKINRTIGFDLSQNDIVTIFNQLGFD-TEINDDVITVLVPSRRKDITIKEDLIEEVARIYGY 478
Cdd:PRK00629 391 VVDVYPL-PKEPTITLRLERINRLLGTEISDEEIVDILKRLGFEvTEVDGDGLTVTVPSWRFDIEIEEDLVEEVARIYGY 469
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 479 DDIPSTLPVfDKVTSGQLTDRQYKTRMVKEVLEGAGLDQAITYSLVSKEDATAFSMQQrQTIDLLMPMSEAHASLRQSLL 558
Cdd:PRK00629 470 DNIPSTPPV-AALTMGGLTEAQRLLRRLRRALAALGYQEVITYSFVSPEDAKLFGLNP-EPLLLLNPISEELSVMRTSLL 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 559 PHLIEAASYNVARKNKDVKLFEIGNVFfaNGEGELPDQVEYLSGILTGDYVVNQWQDKKEtVDFYLAKGVVDRVSEKLNL 638
Cdd:PRK00629 548 PGLLEAVAYNLNRGNKDVALFEIGRVF--LPDGDLPREPEHLAGVLTGNRVEESWGGKRP-VDFFDLKGDVEALLEALGL 624
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 639 EFS--YRRADIDGLHPGRTAEILLENKVVGFIGELHPILAADNDLK-RTYVFELNFDALMAVSVGYINYQPIPRFPGMSR 715
Cdd:PRK00629 625 PEVefVAEFEAAALHPGRSAEIYLDGKVIGFIGELHPKVLKKLDLPgRTYVFELDLDALLEAARKLPKYKPISKFPAVRR 704
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 716 DIALEVDQNIPAADLLSTIHAHGGNILKDTLVFDVYQGEHLEKGKKSIAIRLNYLDTEETLTDERVSKVQAEIEAALIEQ 795
Cdd:PRK00629 705 DLALVVDEDVPAADILKAIKKAGGKLLESVELFDVYEGKGIGEGKKSLAFRLTFQDPDRTLTDEEINAAMDKIVAALEEK 784
|
....*.
gi 584942020 796 -GAVIR 800
Cdd:PRK00629 785 fGAELR 790
|
|
| PheT |
COG0072 |
Phenylalanyl-tRNA synthetase beta subunit [Translation, ribosomal structure and biogenesis]; ... |
1-800 |
0e+00 |
|
Phenylalanyl-tRNA synthetase beta subunit [Translation, ribosomal structure and biogenesis]; Phenylalanyl-tRNA synthetase beta subunit is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439842 [Multi-domain] Cd Length: 793 Bit Score: 978.88 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 1 MLISNEWLKEYVTIDDSVSNLAERITRTGIEVDDLIDYTKDIKNLVVGFVKSKEKHPDADKLNVCQVDIGEDEPVQIVCG 80
Cdd:COG0072 1 MKLSLLWLLLLVEEAALLEELLLLLTGEGLEEEEVEGAAAVVVGVVVVVVVVEEPHPDADDLVVVVVDVGGGEVLVVVCG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 81 APNVDAGQYVIVAKVGGRLPGGIKIKRAKLRGERSEGMICSLQEIGISSNyipksfESGIYVFSEAQVPGTDALQALYLD 160
Cdd:COG0072 81 AANVAVGVVVVAAPGGAVLPGGFKIKKAKIRGVESSGMLCSEEELGLGED------HDGIIVLPPDAPVGGDAREYLGLD 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 161 DQVMEFDLTPNRADALSMIGTAYEVAALYNTKMTKPETtSNELDLSANDELTVTIENEDKVPYYSARVVHDVTIEPSPIW 240
Cdd:COG0072 155 DTVLEIDLTPNRADCLSVRGVARELAALLGAPLKLPAI-EPEVPPAIDDPIPVEIEDPEACPRYAGRVIRGVKVGPSPLW 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 241 MQARLIKAGIRPINNVVDISNYVLLEYGQPLHMFDQDAIGSQqIVVRQANEGEKMTTLDDTERELLTSDIVITNGQTPIA 320
Cdd:COG0072 234 MQERLRAAGIRPINNVVDITNYVMLELGQPLHAFDLDKLKGG-IVVRRAREGEKLTTLDGKERTLDPDDLVIADDEGPLA 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 321 LAGVMGGDFSEVKEQTSNIVIEGAIFDPVSIRHTSRRLNLRSESSSRFEKGIATEFVDEAVDRACYLLQTYANGKVLKDR 400
Cdd:COG0072 313 LAGVMGGEDSEVTEETTDVLLESAYFDPVSIRRTARRLGLHSDASYRFERGVDPALTVAALERATQLILEIAGGEVGPGI 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 401 VSSGELGAFITPIDITADKINRTIGFDLSQNDIVTIFNQLGFDTEINDDVITVLVPSRRKDITIKEDLIEEVARIYGYDD 480
Cdd:COG0072 393 VDVYPEPPEPKTITLRLARINRLLGVEIPAEEIEEILERLGFEVEEDGDGLTVTVPSWRFDIEIEADLIEEVARIYGYDN 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 481 IPSTLPVFDkVTSGQLTDRQYKTRMVKEVLEGAGLDQAITYSLVSKEDATAFSMqQRQTIDLLMPMSEAHASLRQSLLPH 560
Cdd:COG0072 473 IPSTLPRAP-LAGGGLTEAQRLRRRVRRALAARGYQEVITYSFVSPEDADLFGL-RREAVRLANPISEDLSVMRTSLLPG 550
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 561 LIEAASYNVARKNKDVKLFEIGNVFFANGEGElPDQVEYLSGILTGDYVVNQWQDKKETVDFYLAKGVVDRVSEKLNLE- 639
Cdd:COG0072 551 LLEAAAYNLNRGQKDVRLFEIGRVFLPDEGEE-PREPLHLAGVLTGNREPESWGGKARPVDFFDLKGDVEALLAALGVPk 629
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 640 FSYRRADIDGLHPGRTAEILLENKVVGFIGELHPILAADNDLK-RTYVFELNFDALMAVSVGYINYQPIPRFPGMSRDIA 718
Cdd:COG0072 630 LEFEAAEHPALHPGRSAEILLGGKVIGFIGELHPKVLKALDLPgPVYVFELDLDALLELARKVPKYKPISKFPAVRRDLA 709
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 719 LEVDQNIPAADLLSTIHAHGGNILKDTLVFDVYQGEHLEKGKKSIAIRLNYLDTEETLTDERVSKVQAEIEAALIEQ-GA 797
Cdd:COG0072 710 LVVDEDVPAADVLDAIRKAAGKLLEDVRLFDVYEGKGVPEGKKSLAFSLTLQDPDRTLTDEEIDAAMDKIVAALEKKfGA 789
|
...
gi 584942020 798 VIR 800
Cdd:COG0072 790 ELR 792
|
|
| pheT_bact |
TIGR00472 |
phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial; Every known example of ... |
1-800 |
0e+00 |
|
phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial; Every known example of the phenylalanyl-tRNA synthetase, except the monomeric form of mitochondrial, is an alpha 2 beta 2 heterotetramer. The beta subunits break into two subfamilies that are considerably different in sequence, length, and pattern of gaps. This model represents the subfamily that includes the beta subunit from Bacteria other than spirochetes, as well as a chloroplast-encoded form from Porphyra purpurea. The chloroplast-derived sequence is considerably shorter at the amino end. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273097 [Multi-domain] Cd Length: 797 Bit Score: 815.37 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 1 MLISNEWLKEYVTIDDSVSN-LAERITRTGIEVDDLIDYTKDIKNLVVGFVKSKEKHPDADKLNVCQVDIGEDEPVQIVC 79
Cdd:TIGR00472 1 MKISLKWLREYVPLSEIDNEeIAEALTSIGLEVEAVIPFSKPLKGVVVGKVLEVEPHPNADKLKVCKVDIGEKEMLQIVC 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 80 GAPNVDAGQYVIVAKVGGRLPGGIKIKRAKLRGERSEGMICSLQEIGISSNyipksfESGIYVFSEAQVPGTDALQALYL 159
Cdd:TIGR00472 81 GAPNVEAGKKVAVALPGAKLPNGLKIKKSKLRGVESEGMLCSESELGLDEK------SDGIIVLDEDAPLGTDIAEYLGL 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 160 DDQVMEFDLTPNRADALSMIGTAYEVAALYNTKMTKPETTSNELDLSANDELTVTIENEDKVPYYSARVVHDVTIEPSPI 239
Cdd:TIGR00472 155 DDDIIEVSITPNRGDCLSILGIARELAALFDLNLETPVPFEPETTETIDEGFKIEIEDPEVCPFYLGRVIKGVKVKPSPL 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 240 WMQARLIKAGIRPINNVVDISNYVLLEYGQPLHMFDQDAIgSQQIVVRQANEGEKMTTLDDTERELLTSDIVITNGQTPI 319
Cdd:TIGR00472 235 WLKERLRRSGIRPINNIVDITNYVMLELGQPLHAFDADKI-EGNIVVRSAKEGESFTTLDGKERELKKGDLVIADDKKPL 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 320 ALAGVMGGDFSEVKEQTSNIVIEGAIFDPVSIRHTSRRLNLRSESSSRFEKGIATEFVDEAVDRACYLLQTYANGKVLKD 399
Cdd:TIGR00472 314 AIAGVMGGKESGVTDTTTNIFLESAYFNPESIRKTARRLGISTDSSYRFERGVDPELTELALDRALNLILEIFGGEVISV 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 400 RVSSGELGAFITPIDITADKINRTIGFDLSQNDIVTIFNQLGFDTEINDDVITVLVPSRRKDITIKEDLIEEVARIYGYD 479
Cdd:TIGR00472 394 VSDNYKEKAKEKKISLRIKKLNKILGIELSDEEVRDILKRLGFKVEKQKDGWEVTVPSYRHDIEIEEDLIEEIARIYGYD 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 480 DIPSTLPVFDKVTSGQLTDRQYKTRmVKEVLEGAGLDQAITYSLVSKEDATAFSMQQR-QTIDLLMPMSEAHASLRQSLL 558
Cdd:TIGR00472 474 NIPAEPLSVSSKLNKNNENYLLLRK-LRTLLVGLGLNEVITYSFVDPEKAEKFNFPKLeNLVEIKNPLSNERSVLRTSLL 552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 559 PHLIEAASYNVARKNKDVKLFEIGNVFFANGEGELpdQVEYLSGILTGDYVVNQWQDKKETVDFYLAKGVVDRVSEKLNL 638
Cdd:TIGR00472 553 PSLLEVLAYNQNRKNKDVKIFEIGKVFAKDGEAVK--EQLRLAILISGEKNPSSWNHKEEKVDFYDLKGDVESLLELLGL 630
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 639 --EFSYRR-ADIDGLHPGRTAEILLENKVVGFIGELHPILAADNDLK-RTYVFELNFDALMAVSVGYINYQPIPRFPGMS 714
Cdd:TIGR00472 631 sdDVYFKNtAENEELHPGQSATIYLKGKKIGFIGELHPEIAKKYDLKePTFVFELDLDRLLESLKKVPKYRPISKFPAVT 710
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 715 RDIALEVDQNIPAADLLSTIHAHGGNILKDTLVFDVYQGEHLEKGKKSIAIRLNYLDTEETLTDERVSKVQAEIEAALIE 794
Cdd:TIGR00472 711 RDISFLVPKDVPANEIIKLIKKSGLELLEEVELFDVYQGKNIGEGKKSLALRLVLRDKERTLTDEEINKIVEKVLNALKE 790
|
....*..
gi 584942020 795 Q-GAVIR 800
Cdd:TIGR00472 791 KlGAELR 797
|
|
| EMAP |
COG0073 |
tRNA-binding EMAP/Myf domain [Translation, ribosomal structure and biogenesis]; |
1-781 |
4.01e-124 |
|
tRNA-binding EMAP/Myf domain [Translation, ribosomal structure and biogenesis];
Pssm-ID: 439843 [Multi-domain] Cd Length: 773 Bit Score: 390.75 E-value: 4.01e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 1 MLISNEWLKEYVTIDDSVSNLAERITRTGIEVDDlIDYTKDIKNLVVGFVKSKEKHPDADKLNVCQVDIGEdEPVQIVCG 80
Cdd:COG0073 1 MKVSLSWLKEYVDLDLSPEELAEKLTMAGIEVED-FEKVGGLDGLRVGKVLEAEPHPNADKLLVLQVDVGE-ETRQIVCG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 81 APNVDAGQYVIVAKVGGRLPGGIKIKRAKLRGERSEGMICSLQEIGISSNyipksfESGIYVFSEAQVPGTDALQALYLD 160
Cdd:COG0073 79 APNVYAGDKVPEALVGAQVPGVVNLKPRKIRGVESEGMLCSAEELGLGED------HDGILELPEDAPPGDDAEYLLLLD 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 161 DQVMEFDLTPNRADALSMIGtAYEVAALYNTKMTKPETTSNELDLSANDELTVTIENEDKVPYYSARVVHDVTIEPSPIW 240
Cdd:COG0073 153 DVIIEILTTPNRDDLLSVGG-AAREAAALGGLLLKPPAPPVVEGTDDAVLVVVVDDDACDRYYGRVVRGVVNVVVPPPPW 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 241 MQARLIKAGIRPINNVVDISNYVLLEYGQPLHMFDQDAIGSQQIVVRQANEGEKMTTLDDTERELLTSDIVITNGQTPIA 320
Cdd:COG0073 232 LRRLLRRGGRRRIINVVDINNVVLLLLGQPHHAFDDDDLGGGIVVRRRRAEELLLLLLGDTTLLLDDLLLIDDDDDALAA 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 321 LAGVMGGDFSEVKEQTSNIVIEGAIFDPVSIRHTSRRLNLRSESSSRFEKGIATEFVDEAVDRACYLLQTYANGKVLKDR 400
Cdd:COG0073 312 AGGGGGGGGSSGSTTTTTLLLAAAAFFAAAGRRRRRRRLSSRSSRRRRREDDDDPRVAAAAAAAALLLIILGGGGGVAGG 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 401 VSSGELGAFITPIDITADKINRTIGFDLSQNDIVTIFNQLGFDTEINDDVITVLVPSRRKDITIKEDLIEEVARIYGYDD 480
Cdd:COG0073 392 VVDEGLPPPPPRIIRLRRRRRLLLLGIDIDEEELLLLLLLLGFEVEGEGESVVVPPPRRRDDVIEEDEEEEEARRYYYYD 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 481 IPSTLPVFDKVTSGQLTDRQYKTRmVKEVLEGAGLDQAITYSLVSKEDATAFSMQQRQTIDLLMPMSEAHASLRQSLLPH 560
Cdd:COG0073 472 LPPPPPPAPPAVPEPPAARRRLRR-RRRLLLLLGLEEAVTYSSFSELLLALLLLFEAALLLLLPPSSLSSSLLLSLLLLL 550
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 561 LIEAASYNVARKNKDVKLFEIGNVFFANGEGELPDQVEYLSGILTGDYVVNQWQDKKETVDFYLAKGVVDRVSEKLNLEF 640
Cdd:COG0073 551 LLLVLLLLRRRNRNRRLFEGGEVFFGFEGGGLELLLAELEAGGALLLGGGGGAALGLAADDADDLAGVLLLLALLLGLLA 630
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 641 SY--RRADIDGLHPGRTAEILLENKVVGFIGELHPILAADNDLKRTYVFELNFDALMAVSVGYINYQPIPRFPGMSRDIA 718
Cdd:COG0073 631 LLalAAAAPAAAAPGAGGAGGLLLGGGGGLGGLLPVLLKLLLLLLLALLFEVLLDELLLPAAVLLALPLVARPLLRAIVV 710
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 584942020 719 LEVDQNIPAADLLSTIHAHGGNILKDTLVFDVYQGEHLEKGKKSIAIRLNYLDTEETLTDERV 781
Cdd:COG0073 711 DVAAAVAAALAAVAAALALVVALLAVVLLVVVVDVGVGKVLKKLLLSLDLEVTLLDLEELELT 773
|
|
| syfB |
CHL00192 |
phenylalanyl-tRNA synthetase beta chain; Provisional |
160-795 |
2.16e-111 |
|
phenylalanyl-tRNA synthetase beta chain; Provisional
Pssm-ID: 214391 [Multi-domain] Cd Length: 704 Bit Score: 355.17 E-value: 2.16e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 160 DDQVMEFDLTPNRADALSMIGTAYEVAALYNTKMTKPETTSNELDLSANDEltvTIENEDKVP----YYSARVVHDVTIE 235
Cdd:CHL00192 45 SDIILDISSTANRSDVLSIQGLSREISALFNSDPIKLKYYNPSISWFDKLK---NLISNDSSKlncsMFIAVIIENIEIK 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 236 PSPIWMQARLIKAGIRPINNVVDISNYVLLEYGQPLHMFDQDAIGSQ------QIVVRQANEGEKMTTLDDTERELLTSD 309
Cdd:CHL00192 122 DSPKWLQNRLSSSGFKSLNNLTDIQNYIMLETGQPIEIYDLDKIYSKnttsslALSSKFALQKSSFIASNSKNIELENNI 201
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 310 IVITNGQTPIALAGVMGGDFSEVKEQTSNIVIEGAIFDPVSIRHTSRRLNLRSESSSRFEKGIATEFVDEAVDRACYLLQ 389
Cdd:CHL00192 202 LVVQANNVIISIAGIISNEEIICDKNTKSILIEASIFDAAVIRKSSRKLGLRTDRSIRYEKSLKNDNLLEAYYRLVSLLR 281
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 390 TYANGKVLKDRVSSGELGAFITPIDITADKINRTIG--------FDLSQNDIVTIFNQLGFDTEINDDVIT--VLVPSRR 459
Cdd:CHL00192 282 ILNPKLKCKFHFIYKKIKNSSRRIKLSYKKIKDILGpikintntRYLSPKEITNALKRLNFKITYDSLKLNweVLIPSYR 361
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 460 KDITIKE-DLIEEVARIYGYDDIPSTLPvfdKVTSGQLTDRQYKTR-MVKEVLEGAGLDQAITYSLVSKEdatAFSMQQr 537
Cdd:CHL00192 362 KDDIVREiDVIEEIARIYGFNNFLSKLP---NIKFIGRLDIDYNTRdKIRSYLRNLGLTELIHYSLVKQE---SFSKNE- 434
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 538 qtIDLLMPMSEAHASLRQSLLPHLIEAASYNVARKNKDVKLFEIGNVFFANGEGELpDQVEYLSGILTGDYVVNQWQDKK 617
Cdd:CHL00192 435 --IKLKNPLIKDYSTLRSSLLPGLIEAVQENLKQGNSTLEGFEIGHVFNLDSSSII-EETELAGGIFGGIDIRSSWSEKA 511
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 618 ETVDFYLAKGVVDRVSEKLNLEFSYR-RADIDG---LHPGRTAEILLEN-KVVGFIGELHPILAADNDL-KRTYVFELNF 691
Cdd:CHL00192 512 QSLNWFEAKGIIENFFQKLNLPIYWKkYSDLDEkinFHPYCTSEIFLSNgQKIGIFGQLHPLLANKLNLnTEIYLFEINL 591
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 692 DALMAV--SVGYINYQPIPRFPGMSRDIALEVDQNIPAADLLSTIHAHGGNILKDTLVFDVYQGEHLEKGKKSIAIRLNY 769
Cdd:CHL00192 592 DILQYSiqQNNLISYQPYSSYPKIIRDLSFIIKKSISISKIKELIYQNGDNLLESITLFDYYKGKSIPNGHTSLGLRLTF 671
|
650 660
....*....|....*....|....*.
gi 584942020 770 LDTEETLTDERVSKVQAEIEAALIEQ 795
Cdd:CHL00192 672 QSENKTLTNEEIDRIQQNLQKVLEKK 697
|
|
| tRNA_synthFbeta |
pfam17759 |
Phenylalanyl tRNA synthetase beta chain CLM domain; This domain corresponds to the catalytic ... |
481-691 |
3.02e-86 |
|
Phenylalanyl tRNA synthetase beta chain CLM domain; This domain corresponds to the catalytic like domain (CLM) in the beta chain of phe tRNA synthetase.
Pssm-ID: 465487 [Multi-domain] Cd Length: 214 Bit Score: 272.12 E-value: 3.02e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 481 IPSTLPVFDkVTSGQLTDRQYKTRMVKEVLEGAGLDQAITYSLVSKEDATAF--SMQQRQTIDLLMPMSEAHASLRQSLL 558
Cdd:pfam17759 1 IPSTLPKGP-TTGGGLTPEQKLRRRVRDLLAAAGFTEVITYSFTSPKDLDKLleDDPRRKAVKLANPLSEELSVMRTSLL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 559 PHLIEAASYNVARKNKDVKLFEIGNVFFANGEGELPDQVEYLSGILTGDYVVNQWQDKKETVDFYLAKGVVDRVSEKLNL 638
Cdd:pfam17759 80 PGLLETLAYNLNRGNPDVRLFEIGRVFLPDELEELPREPRRLAGLLTGKRLPESWQGKARPVDFYDLKGIVEALLAALGI 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 584942020 639 -EFSYRRADIDGLHPGRTAEILLENKVVGFIGELHPILAADNDLK-RTYVFELNF 691
Cdd:pfam17759 160 dDYEFEAADHPALHPGRSAEILVGGKVIGFIGELHPEVAKNFDLPqPVYVFELDL 214
|
|
| B3_4 |
pfam03483 |
B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA ... |
222-393 |
5.23e-80 |
|
B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA synthetase proteins.
Pssm-ID: 427327 [Multi-domain] Cd Length: 174 Bit Score: 254.39 E-value: 5.23e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 222 PYYSARVVHDVT-IEPSPIWMQARLIKAGIRPINNVVDISNYVLLEYGQPLHMFDQDAIgSQQIVVRQANEGEKMTTLDD 300
Cdd:pfam03483 3 PRYFGRVIRGVKkNRPSPEWLQRRLRRAGIRPINNVVDITNYVMLELGQPLHAFDLDKI-AGDIVVRLAKGGEKFTTLDG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 301 TERELLTSDIVITNGQTPIALAGVMGGDFSEVKEQTSNIVIEGAIFDPVSIRHTSRRLNLRSESSSRFEKGIATEFVDEA 380
Cdd:pfam03483 82 KERELDPGDLVIADDDGPVALAGIMGGEESEVTEDTTNIFLESAGFDPVAIRKTARRLGLRTDASYRFERGVDPELVEAA 161
|
170
....*....|...
gi 584942020 381 VDRACYLLQTYAN 393
Cdd:pfam03483 162 LDRATALLLELCG 174
|
|
| B3_4 |
smart00873 |
B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA ... |
222-392 |
1.03e-67 |
|
B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA synthetase proteins.
Pssm-ID: 214876 [Multi-domain] Cd Length: 174 Bit Score: 221.75 E-value: 1.03e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 222 PYYSARVVHDVTIE-PSPIWMQARLIKAGIRPINNVVDISNYVLLEYGQPLHMFDQDAIGSQQIVVRQANEGEKMTTLDD 300
Cdd:smart00873 2 PRYLGRVIRGVKNTrPSPEWLQERLHRAGIRPINNVVDITNYVSLETGQPLHAFDLDKIKGKDIPLRRAKEGEKFETLDG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 301 TERELLTSDIVITNGQTPIALAGVMGGDFSEVKEQTSNIVIEGAIFDPVSIRHTSRRLNLRSESSSRFEKGIATEFVDEA 380
Cdd:smart00873 82 KEYELDEGDLVIADDEGPLALAGVMGGEESEVTENTTVIFLEPAIFSPRTIRITARTLNLFTDASGRFERGVDPELVELA 161
|
170
....*....|..
gi 584942020 381 VDRACYLLQTYA 392
Cdd:smart00873 162 LDRAAALLLEIC 173
|
|
| PheRS_beta_core |
cd00769 |
Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II ... |
503-694 |
1.13e-66 |
|
Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA, PheRS is an exception in that it attaches the amino acid at the 2'-OH group, like class I aaRSs. PheRS is an alpha-2/ beta-2 tetramer. While the alpha chain contains a catalytic core domain, the beta chain has a non-catalytic core domain.
Pssm-ID: 238392 [Multi-domain] Cd Length: 198 Bit Score: 219.82 E-value: 1.13e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 503 TRMVKEVLEGAGLDQAITYSLVSKEDATAFSMQQRQTIDLLMPMSEAHASLRQSLLPHLIEAASYNVARKNKDVKLFEIG 582
Cdd:cd00769 6 ERKLRRLLAGLGFQEVITYSLTSPEEAELFDGGLDEAVELSNPLSEEYSVLRTSLLPGLLDALARNLNRKNKPLRLFEIG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 583 NVFFANGEGelPDQVEYLSGILTGDYVVNQWQDKKETVDFYLAKGVVDRVSEKLN--LEFSYRRADIDGLHPGRTAEILL 660
Cdd:cd00769 86 RVFLKDEDG--PEEEEHLAALLSGNREPESWQGKGRPVDFYDAKGILEALLRALGiiVEFELEELDADLFHPGRSAKIYV 163
|
170 180 190
....*....|....*....|....*....|....*
gi 584942020 661 ENKVVGFIGELHPILAADNDLK-RTYVFELNFDAL 694
Cdd:cd00769 164 NGEVIGFIGELHPEVLKEFDLKePVYAFELDLDAL 198
|
|
| tRNA_bind_bactPheRS |
cd02796 |
tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain. ... |
45-153 |
2.39e-45 |
|
tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain. PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate the 2'OH of the terminal ribose of tRNA they belong functionally to class 1 aaRSs. This domain has general tRNA binding properties and is believed to direct tRNAphe to the active site of the enzyme.
Pssm-ID: 239196 [Multi-domain] Cd Length: 103 Bit Score: 157.67 E-value: 2.39e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 45 LVVGFVKSKEKHPDADKLNVCQVDIGEDEPVQIVCGAPNVDAGQYVIVAKVGGRLPGGIKIKRAKLRGERSEGMICSLQE 124
Cdd:cd02796 1 VVVGKVLEVEPHPNADKLNVCKVDIGENKPLQIVCGAPNVRAGDKVVVALPGAVLPGGLKIKKRKLRGVESEGMLCSAKE 80
|
90 100
....*....|....*....|....*....
gi 584942020 125 IGISSNyipksfESGIYVFSEAQVPGTDA 153
Cdd:cd02796 81 LGLGED------SDGIIELPEDAPVGTDI 103
|
|
| FDX-ACB |
smart00896 |
Ferredoxin-fold anticodon binding domain; This is the anticodon binding domain found in some ... |
708-800 |
2.85e-31 |
|
Ferredoxin-fold anticodon binding domain; This is the anticodon binding domain found in some phenylalanyl tRNA synthetases. The domain has a ferredoxin fold, consisting of an alpha+beta sandwich with anti-parallel beta-sheets (beta-alpha-beta x2).
Pssm-ID: 214893 [Multi-domain] Cd Length: 93 Bit Score: 117.53 E-value: 2.85e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 708 PRFPGMSRDIALEVDQNIPAADLLSTIHAHGGNILKDTLVFDVYQGeHLEKGKKSIAIRLNYLDTEETLTDERVSKVQAE 787
Cdd:smart00896 1 SKFPAVRRDLAFVVDEDVPAAELLDAIREAGGDLLEDVRLFDVYEG-GIPEGKKSLAYRLTYQSPDRTLTDEEVNAIHDK 79
|
90
....*....|....
gi 584942020 788 IEAALIEQ-GAVIR 800
Cdd:smart00896 80 IVAALEKKfGAELR 93
|
|
| FDX-ACB |
pfam03147 |
Ferredoxin-fold anticodon binding domain; This is the anticodon binding domain found in some ... |
708-800 |
5.98e-30 |
|
Ferredoxin-fold anticodon binding domain; This is the anticodon binding domain found in some phenylalanyl tRNA synthetases. The domain has a ferredoxin fold.
Pssm-ID: 460826 [Multi-domain] Cd Length: 94 Bit Score: 113.73 E-value: 5.98e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 708 PRFPGMSRDIALEVDQNIPAADLLSTIHAHGGNILKDTLVFDVYQGEHLEKGKKSIAIRLNYLDTEETLTDERVSKVQAE 787
Cdd:pfam03147 1 SKYPAVRRDLAFVVDEDVPAADILKAIREAGGELLESVELFDVYRGEKIPEGKKSLAFRLTFQSPERTLTDEEVNAIIEK 80
|
90
....*....|....
gi 584942020 788 IEAALIEQ-GAVIR 800
Cdd:pfam03147 81 IVEALEKKfGAELR 94
|
|
| tRNA_bindingDomain |
cd02153 |
The tRNA binding domain is also known as the Myf domain in literature. This domain is found in ... |
45-152 |
1.14e-29 |
|
The tRNA binding domain is also known as the Myf domain in literature. This domain is found in a diverse collection of tRNA binding proteins, including prokaryotic phenylalanyl tRNA synthetases (PheRS), methionyl-tRNA synthetases (MetRS), human tyrosyl-tRNA synthetase(hTyrRS), Saccharomyces cerevisiae Arc1p, Thermus thermophilus CsaA, Aquifex aeolicus Trbp111, human p43 and human EMAP-II. PheRS, MetRS and hTyrRS aminoacylate their cognate tRNAs. Arc1p is a transactivator of yeast methionyl-tRNA and glutamyl-tRNA synthetases. The molecular chaperones Trbp111 and CsaA also contain this domain. CsaA has export related activities; Trbp111 is structure-specific recognizing the L-shape of the tRNA fold. This domain has general tRNA binding properties. In a subset of this family this domain has the added capability of a cytokine. For example the p43 component of the Human aminoacyl-tRNA synthetase complex is cleaved to release EMAP-II cytokine. EMAP-II has multiple activities during apoptosis, angiogenesis and inflammation and participates in malignant transformation. An EMAP-II-like cytokine is released from hTyrRS upon cleavage. The active cytokine heptapeptide locates to this domain. For homodimeric members of this group which include CsaA, Trbp111 and Escherichia coli MetRS this domain acts as a dimerization domain.
Pssm-ID: 239066 [Multi-domain] Cd Length: 99 Bit Score: 113.00 E-value: 1.14e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 45 LVVGFVKSKEKHPDADKLNVCQVDIGEDEPVQIVCGAPNVDA-----GQYVIVAKVggrlpggikIKRAKLRGERSEGMI 119
Cdd:cd02153 1 LRVGKIVEAEPHPNADKLYVLKVDIGEEKPRQIVSGAANVYPpeelvGKKVVVAVN---------LKPKKLRGVESEGML 71
|
90 100 110
....*....|....*....|....*....|...
gi 584942020 120 CSLQEIGISSNyipksfESGIYVFSEAQVPGTD 152
Cdd:cd02153 72 LSAEELGLEEG------SVGILELPEDAPVGDR 98
|
|
| B5 |
smart00874 |
tRNA synthetase B5 domain; This domain is found in phenylalanine-tRNA synthetase beta subunits. |
411-478 |
8.23e-25 |
|
tRNA synthetase B5 domain; This domain is found in phenylalanine-tRNA synthetase beta subunits.
Pssm-ID: 197942 [Multi-domain] Cd Length: 68 Bit Score: 97.95 E-value: 8.23e-25
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 584942020 411 TPIDITADKINRTIGFDLSQNDIVTIFNQLGFDTEINDDVITVLVPSRRKDITIKEDLIEEVARIYGY 478
Cdd:smart00874 1 RTITLRLERINRLLGLEILAEEIEEILKRLGFEVEVSGDTLEVTVPSYRFDILIEADLIEEVARIYGY 68
|
|
| tRNA_bind |
pfam01588 |
Putative tRNA binding domain; This domain is found in prokaryotic methionyl-tRNA synthetases, ... |
45-140 |
3.12e-24 |
|
Putative tRNA binding domain; This domain is found in prokaryotic methionyl-tRNA synthetases, prokaryotic phenylalanyl tRNA synthetases the yeast GU4 nucleic-binding protein (G4p1 or p42, ARC1), human tyrosyl-tRNA synthetase, and endothelial-monocyte activating polypeptide II. G4p1 binds specifically to tRNA form a complex with methionyl-tRNA synthetases. In human tyrosyl-tRNA synthetase this domain may direct tRNA to the active site of the enzyme. This domain may perform a common function in tRNA aminoacylation.
Pssm-ID: 396251 [Multi-domain] Cd Length: 96 Bit Score: 97.31 E-value: 3.12e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 45 LVVGFVKSKEKHPDADKLNVCQVDIGEDEPVQIVCGAPNVDAGQYViVAKVGGRLPggiKIKRAKLRGERSEGMICSLQE 124
Cdd:pfam01588 1 LRVGKVVEAERHPNADKLLVCKVDVGEEEPRQIVSGAVNVYPPEEL-VGRLVVVVA---NLKPAKLRGVESEGMILSAEE 76
|
90
....*....|....*....
gi 584942020 125 IGISSNYI---PKSFESGI 140
Cdd:pfam01588 77 LDGGSVGLlepPADVPPGT 95
|
|
| B5 |
pfam03484 |
tRNA synthetase B5 domain; This domain is found in phenylalanine-tRNA synthetase beta subunits. |
413-478 |
7.55e-23 |
|
tRNA synthetase B5 domain; This domain is found in phenylalanine-tRNA synthetase beta subunits.
Pssm-ID: 460942 [Multi-domain] Cd Length: 67 Bit Score: 92.46 E-value: 7.55e-23
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 584942020 413 IDITADKINRTIGFDLSQNDIVTIFNQLGFD-TEINDDVITVLVPSRRKDITIKEDLIEEVARIYGY 478
Cdd:pfam03484 1 ITLRLDRINRLLGIDLSAEEIVEILERLGFEvEEEDGDTLTVTVPSYRPDILHEADLIEEVARIYGY 67
|
|
| PLN02265 |
PLN02265 |
probable phenylalanyl-tRNA synthetase beta chain |
414-695 |
2.35e-18 |
|
probable phenylalanyl-tRNA synthetase beta chain
Pssm-ID: 215149 [Multi-domain] Cd Length: 597 Bit Score: 89.74 E-value: 2.35e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 414 DITADKINRTIGFDLSQNDIVTIFNQLGFDTEI---NDDVITVLVPSRRKDITIKEDLIEEVARIYGYDDIPSTLPVFDK 490
Cdd:PLN02265 313 EVDLSYINSSIGVSLDAEEVASLLNKMQLQAEQssdDGCTIRVSVPPTRSDILHPCDVAEDVAIAYGYNNIPKRKPKSMT 392
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 491 VtSGQLTDRQYkTRMVKEVLEGAGLDQAITYSLVSKEDatAFSMQQRQ-----TIDLLMPMSEAHASLRQSLLPHLIEAA 565
Cdd:PLN02265 393 V-GKQQPLNQF-SDLLRAEVAMAGFTEVLTWILCSHKE--NFAMLNREddgnsAVIIGNPRSADFEVVRTSLLPGLLKTL 468
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 566 SYnvarkNKD----VKLFEIGNVFFANGEGEL-PDQVEYLSGILTGdyvvnqwqdkkETVDFYLAKGVVDRVSEKL---- 636
Cdd:PLN02265 469 GH-----NKDapkpIKLFEVSDVVLLDESKDVgARNSRRLAALYCG-----------TTSGFEVIHGLVDRIMEVLgipf 532
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 584942020 637 -----NLEFSYRRADIDGLHPGRTAEILLENKVVGFIGELHP-ILAADNDLKRTYVFELNFDALM 695
Cdd:PLN02265 533 veigdNNGYYVEPSNEPEYFPGRQASIIYKGKHVGTFGIVHPeVLNNFDIPDPCSFLELDLEPLL 597
|
|
| tRNA_bind_EMAP-II_like |
cd02799 |
tRNA-binding-domain-containing EMAP2-like proteins. This family contains a diverse fraction of ... |
44-119 |
1.05e-13 |
|
tRNA-binding-domain-containing EMAP2-like proteins. This family contains a diverse fraction of tRNA binding proteins, including Caenorhabditis elegans methionyl-tRNA synthetase (CeMetRS), human tyrosyl- tRNA synthetase (hTyrRS), Saccharomyces cerevisiae Arc1p, human p43 and EMAP2. CeMetRS and hTyrRS aminoacylate their cognate tRNAs. Arc1p is a transactivator of yeast methionyl-tRNA and glutamyl-tRNA synthetases. This domain has general tRNA binding properties. In a subset of this family this domain has the added capability of a cytokine. For example the p43 component of the Human aminoacyl-tRNA synthetase complex is cleaved to release EMAP-II cytokine. EMAP-II has multiple activities during apoptosis, angiogenesis and inflammation and participates in malignant transformation. A EMAP-II-like cytokine also is released from hTyrRS upon cleavage. The active cytokine heptapeptide locates to this domain.
Pssm-ID: 239198 [Multi-domain] Cd Length: 105 Bit Score: 67.64 E-value: 1.05e-13
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 584942020 44 NLVVGFVKSKEKHPDADKLNVCQVDIGEDEPVQIVCGAPNvdagqYVIVAKVGGRLPGGI-KIKRAKLRGERSEGMI 119
Cdd:cd02799 7 DIRVGKILKVRKHPDADSLYVEEIDLGEEEPRTIVSGLVK-----FVPLEQMQNRLVVVLcNLKPRKMRGVKSQGMV 78
|
|
| PRK12267 |
PRK12267 |
methionyl-tRNA synthetase; Reviewed |
30-119 |
3.43e-09 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 237028 [Multi-domain] Cd Length: 648 Bit Score: 60.20 E-value: 3.43e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 30 IEVDDlidYTK-DIKnlvVGFVKSKEKHPDADKLNVCQVDIGEDEPVQIVCG-----APNVDAGQYV-IVAkvggrlpgg 102
Cdd:PRK12267 543 ITIDD---FDKvELR---VAEVLEAEKVEKSDKLLKLQVDLGEEEPRQIVSGiakfyPPEELVGKKVvVVA--------- 607
|
90
....*....|....*..
gi 584942020 103 iKIKRAKLRGERSEGMI 119
Cdd:PRK12267 608 -NLKPAKLMGEESQGMI 623
|
|
| B3/B4 |
COG3382 |
B3/B4 domain (DNA/RNA-binding domain of Phe-tRNA-synthetase) [General function prediction only] ... |
244-410 |
5.35e-08 |
|
B3/B4 domain (DNA/RNA-binding domain of Phe-tRNA-synthetase) [General function prediction only];
Pssm-ID: 442609 [Multi-domain] Cd Length: 233 Bit Score: 54.47 E-value: 5.35e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 244 RLIK-AGIRPINNVVDISNYVLLEYGQPLHMFDQDAIGSqQIVVRQANEGEKMTTLDDTERELLTSDIVItngqtpiaLA 322
Cdd:COG3382 88 RVLKgGGLPRINPLVDLYNAVSLRYLLPIGGYDLDKIEG-DLRLRLARGGESFLPIGGDEEEPPEPGEVV--------YA 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 323 ---GVMG-------GDFSEVKEQTSNIVIEGAIFDPVSirhtsrrlnlrsesssrfekgiaTEFVDEAVDRACYLLQTYA 392
Cdd:COG3382 159 ddeGVFCrrwpwrdSERTKVTEETKNALFIIEGLPGVS-----------------------AEDLEAALDELAELLERYL 215
|
170
....*....|....*...
gi 584942020 393 NGKVLKDRVSSGELGAFI 410
Cdd:COG3382 216 GGEVVKTRILDADNPEFE 233
|
|
| pheS_mito |
TIGR00469 |
phenylalanyl-tRNA synthetase, mitochondrial; Unlike all other known phenylalanyl-tRNA ... |
704-798 |
2.43e-07 |
|
phenylalanyl-tRNA synthetase, mitochondrial; Unlike all other known phenylalanyl-tRNA synthetases, the mitochondrial form demonstrated from yeast is monomeric. It is similar to but longer than the alpha subunit (PheS) of the alpha 2 beta 2 form found in Bacteria, Archaea, and eukaryotes, and shares the characteristic motifs of class II aminoacyl-tRNA ligases. This model models the experimental example from Saccharomyces cerevisiae (designated MSF1) and its orthologs from other eukaryotic species. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 129561 [Multi-domain] Cd Length: 460 Bit Score: 53.93 E-value: 2.43e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 704 YQPIPRFPGMSRDIALEVDQNIP------AADLLSTIHAHGGNILKDTLVFDVYQgeHLEKGKKSIAIRLNYLDTEETLT 777
Cdd:TIGR00469 360 FKPISHHPGCFNDLAFWLPEDIEddagfhENDFMDIIRNIAGDLVEQIKLVDKFK--HPKTGKKSMCFRINYQHMDRNLT 437
|
90 100
....*....|....*....|.
gi 584942020 778 DERVSKVQAEIEAALIEQGAV 798
Cdd:TIGR00469 438 NAEVNEIHDMIASALVDEFNV 458
|
|
| PLN02610 |
PLN02610 |
probable methionyl-tRNA synthetase |
32-119 |
1.71e-06 |
|
probable methionyl-tRNA synthetase
Pssm-ID: 215329 [Multi-domain] Cd Length: 801 Bit Score: 51.70 E-value: 1.71e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 32 VDDLIDYTK-DIKnlvVGFVKSKEKHPDADKLNVCQVDIGEDEPVQIVCGAPnvdagQYVIVAKVGGRLPGGI-KIKRAK 109
Cdd:PLN02610 634 AEREIDVSRlDIR---VGLIVKAEKHPDADSLYVEEIDVGEGAPRTVVSGLV-----KYIPLEEMQNRKVCVLcNLKPAA 705
|
90
....*....|
gi 584942020 110 LRGERSEGMI 119
Cdd:PLN02610 706 MRGIKSQAMV 715
|
|
| tRNA_bind_EcMetRS_like |
cd02800 |
tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like ... |
37-119 |
3.75e-06 |
|
tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins. This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties. MetRS aminoacylates methionine transfer RNAs (tRNAmet). AaTrbp111 is structure-specific molecular chaperone recognizing the L-shape of the tRNA fold. AaTrbp111 plays a role in nuclear trafficking of tRNAs. The functional unit of EcMetRs and AaTrbp111 is a homodimer, this domain acts as the dimerization domain.
Pssm-ID: 239199 [Multi-domain] Cd Length: 105 Bit Score: 46.34 E-value: 3.75e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 37 DYTK-DIKnlvVGFVKSKEKHPDADKLNVCQVDIGEdEPVQIVCG-----APNVDAGQYVIVAkvggrlpggIKIKRAKL 110
Cdd:cd02800 5 DFAKvDLR---VGKVLEAERVEGSDKLLKLTVDLGE-EERQIVSGiakfyPPEELVGKKVVVV---------ANLKPRKL 71
|
....*....
gi 584942020 111 RGERSEGMI 119
Cdd:cd02800 72 RGVESQGMI 80
|
|
| metG_C_term |
TIGR00399 |
methionyl-tRNA synthetase C-terminal region/beta chain; The methionyl-tRNA synthetase (metG) ... |
36-119 |
2.63e-05 |
|
methionyl-tRNA synthetase C-terminal region/beta chain; The methionyl-tRNA synthetase (metG) is a class I amino acyl-tRNA ligase. This model describes a region of the methionyl-tRNA synthetase that is present at the C-terminus of MetG in some species (E. coli, B. subtilis, Thermotoga maritima, Methanobacterium thermoautotrophicum), and as a separate beta chain in Aquifex aeolicus. It is absent in a number of other species (e.g. Mycoplasma genitalium, Mycobacterium tuberculosis), while Pyrococcus horikoshii has both a full length MetG and a second protein homologous to the beta chain only. Proteins hit by this model should be called methionyl-tRNA synthetase beta chain if and only if the model metG hits a separate protein not also hit by this model. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273059 [Multi-domain] Cd Length: 137 Bit Score: 44.73 E-value: 2.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 36 IDYTKDIkNLVVGFVKSKEKHPDADKLNVCQVDIGeDEPVQIVCGApnvdAGQYVIVAKVGGRLPGGIKIKRAKLRGERS 115
Cdd:TIGR00399 34 IDDFEKV-DLRVGKILKAERVEKSDKLLKLKLDLG-DEKRQIVSGI----AGYYTPEELVGKKVIVVANLKPAKLFGVKS 107
|
....
gi 584942020 116 EGMI 119
Cdd:TIGR00399 108 EGMI 111
|
|
| metG |
PRK00133 |
methionyl-tRNA synthetase; Reviewed |
37-119 |
1.74e-04 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 234655 [Multi-domain] Cd Length: 673 Bit Score: 45.14 E-value: 1.74e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942020 37 DYTK-DIKnlvVGFVKSKEKHPDADKLNVCQVDIGEdEPVQIVCGApnvdAGQY----------VIVAkvggrlpggiKI 105
Cdd:PRK00133 572 DFAKvDLR---VAKIVEAEKVEGADKLLKLTLDLGE-ETRQVFSGI----KSAYdpeelvgklvVMVA----------NL 633
|
90
....*....|....
gi 584942020 106 KRAKLRGERSEGMI 119
Cdd:PRK00133 634 APRKMKFGVSEGMV 647
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