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Conserved domains on  [gi|584942022|gb|EWK66123|]
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cell division protein ZapA [Staphylococcus aureus S56450]

Protein Classification

cell division protein ZapA( domain architecture ID 3261)

cell division protein ZapA interacts with FtsZ, a mid-cell cytokinetic structure termed the Z-ring that recruits a hierarchy of fission related proteins early in the cell cycle

CATH:  1.10.20.30
Gene Ontology:  GO:0000917
SCOP:  4001324

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK14126 super family cl01146
cell division protein ZapA; Provisional
 5-82 5.21e-22

cell division protein ZapA; Provisional


The actual alignment was detected with superfamily member PRK14126:

Pssm-ID: 470096  Cd Length: 85  Bit Score: 81.35  E-value: 5.21e-22
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 584942022  5 KNKVNVSINDQLFTIVGEDNPEHIRYVAHLVDDKIKELGYKAAGLDTSRKAILTAVNIMHEKVLLEEENRRLKQQIHK 82
Cdd:PRK14126  6 KTRINVEIYGQQYTIVGDESTSHIRMVAAIVDDKMRELNEKNPSLDTSKLAVLTAVNVIHDYIKLKEEYEKLKESMTK 83
 
Name Accession Description Interval E-value
PRK14126 PRK14126
cell division protein ZapA; Provisional
 5-82 5.21e-22

cell division protein ZapA; Provisional


Pssm-ID: 172616  Cd Length: 85  Bit Score: 81.35  E-value: 5.21e-22
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 584942022  5 KNKVNVSINDQLFTIVGEDNPEHIRYVAHLVDDKIKELGYKAAGLDTSRKAILTAVNIMHEKVLLEEENRRLKQQIHK 82
Cdd:PRK14126  6 KTRINVEIYGQQYTIVGDESTSHIRMVAAIVDDKMRELNEKNPSLDTSKLAVLTAVNVIHDYIKLKEEYEKLKESMTK 83
ZapA COG3027
Cell division protein ZapA, inhibits GTPase activity of FtsZ [Cell cycle control, cell ...
 5-86 2.80e-18

Cell division protein ZapA, inhibits GTPase activity of FtsZ [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442263 [Multi-domain]  Cd Length: 94  Bit Score: 72.22  E-value: 2.80e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942022  5 KNKVNVSINDQLFTIV-GEDNPEHIRYVAHLVDDKIKELGYKAAGLDTSRKAILTAVNIMHEKVLLEEENRRLKQQIHKL 83
Cdd:COG3027   3 MNRVTVTILGREYRLAcPEGEEEHLREAAAYVDEKMREIREKGGVLGTERLAVLAALNLADELLKLKEELEELEERLEEL 82


                ...
gi 584942022 84 QQR 86
Cdd:COG3027  83 EEK 85
ZapA pfam05164
Cell division protein ZapA; ZapA is a cell division protein which interacts with FtsZ. FtsZ is ...
 8-86 1.48e-12

Cell division protein ZapA; ZapA is a cell division protein which interacts with FtsZ. FtsZ is part of a mid-cell cytokinetic structure termed the Z-ring that recruits a hierarchy of fission related proteins early in the bacterial cell cycle. The interaction of FtsZ with ZapA drives its polymerization and promotes FtsZ filament bundling thereby contributing to the spatio-temporal tuning of the Z-ring.


Pssm-ID: 461565 [Multi-domain]  Cd Length: 85  Bit Score: 57.17  E-value: 1.48e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942022   8 VNVSINDQLFTIVG-EDNPEHIRYVAHLVDDKIKELGYKAAGLDTSRKAILTAVNIMHEKVLLEEENRRLKQQ----IHK 82
Cdd:pfam05164  1 VTVTILGREYTLACpEGEEEYLRKAAKYVDEKIKEIRESGGVLSTERLAVLAALNLADELLKLKREAEELEEEleerLEE 80


                 ....
gi 584942022  83 LQQR 86
Cdd:pfam05164 81 LAER 84
 
Name Accession Description Interval E-value
PRK14126 PRK14126
cell division protein ZapA; Provisional
 5-82 5.21e-22

cell division protein ZapA; Provisional


Pssm-ID: 172616  Cd Length: 85  Bit Score: 81.35  E-value: 5.21e-22
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 584942022  5 KNKVNVSINDQLFTIVGEDNPEHIRYVAHLVDDKIKELGYKAAGLDTSRKAILTAVNIMHEKVLLEEENRRLKQQIHK 82
Cdd:PRK14126  6 KTRINVEIYGQQYTIVGDESTSHIRMVAAIVDDKMRELNEKNPSLDTSKLAVLTAVNVIHDYIKLKEEYEKLKESMTK 83
ZapA COG3027
Cell division protein ZapA, inhibits GTPase activity of FtsZ [Cell cycle control, cell ...
 5-86 2.80e-18

Cell division protein ZapA, inhibits GTPase activity of FtsZ [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442263 [Multi-domain]  Cd Length: 94  Bit Score: 72.22  E-value: 2.80e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942022  5 KNKVNVSINDQLFTIV-GEDNPEHIRYVAHLVDDKIKELGYKAAGLDTSRKAILTAVNIMHEKVLLEEENRRLKQQIHKL 83
Cdd:COG3027   3 MNRVTVTILGREYRLAcPEGEEEHLREAAAYVDEKMREIREKGGVLGTERLAVLAALNLADELLKLKEELEELEERLEEL 82


                ...
gi 584942022 84 QQR 86
Cdd:COG3027  83 EEK 85
ZapA pfam05164
Cell division protein ZapA; ZapA is a cell division protein which interacts with FtsZ. FtsZ is ...
 8-86 1.48e-12

Cell division protein ZapA; ZapA is a cell division protein which interacts with FtsZ. FtsZ is part of a mid-cell cytokinetic structure termed the Z-ring that recruits a hierarchy of fission related proteins early in the bacterial cell cycle. The interaction of FtsZ with ZapA drives its polymerization and promotes FtsZ filament bundling thereby contributing to the spatio-temporal tuning of the Z-ring.


Pssm-ID: 461565 [Multi-domain]  Cd Length: 85  Bit Score: 57.17  E-value: 1.48e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584942022   8 VNVSINDQLFTIVG-EDNPEHIRYVAHLVDDKIKELGYKAAGLDTSRKAILTAVNIMHEKVLLEEENRRLKQQ----IHK 82
Cdd:pfam05164  1 VTVTILGREYTLACpEGEEEYLRKAAKYVDEKIKEIRESGGVLSTERLAVLAALNLADELLKLKREAEELEEEleerLEE 80


                 ....
gi 584942022  83 LQQR 86
Cdd:pfam05164 81 LAER 84
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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