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Conserved domains on  [gi|587732449|gb|EXA30165|]
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hypothetical protein FOVG_18429 [Fusarium oxysporum f. sp. pisi HDV247]

Protein Classification

alpha/beta fold hydrolase( domain architecture ID 11426811)

alpha/beta hydrolase family protein catalyzes the hydrolysis of substrates with different chemical composition or physicochemical properties using a nucleophile-His-acid catalytic triad

PubMed:  1409539|12369917

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
6-156 6.99e-21

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


:

Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 88.13  E-value: 6.99e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 587732449   6 TINDVELSFDDRGmvSSEPTIVCLPGLGQDHRGYKYILPFLVGKYRVIRIVWKGHGDNREPMDKWSVEDQASDTIALLDS 85
Cdd:COG0596    8 TVDGVRLHYREAG--PDGPPVVLLHGLPGSSYEWRPLIPALAAGYRVIAPDLRGHGRSDKPAGGYTLDDLADDLAALLDA 85
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 587732449  86 LQVQTFVPISHSHGGWCAMEMAARLGkERVPAILLTDLILTRpppeFIKHLQMTQNEDTRYEAQAALVKGW 156
Cdd:COG0596   86 LGLERVVLVGHSMGGMVALELAARHP-ERVAGLVLVDEVLAA----LAEPLRRPGLAPEALAALLRALART 151
 
Name Accession Description Interval E-value
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
6-156 6.99e-21

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 88.13  E-value: 6.99e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 587732449   6 TINDVELSFDDRGmvSSEPTIVCLPGLGQDHRGYKYILPFLVGKYRVIRIVWKGHGDNREPMDKWSVEDQASDTIALLDS 85
Cdd:COG0596    8 TVDGVRLHYREAG--PDGPPVVLLHGLPGSSYEWRPLIPALAAGYRVIAPDLRGHGRSDKPAGGYTLDDLADDLAALLDA 85
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 587732449  86 LQVQTFVPISHSHGGWCAMEMAARLGkERVPAILLTDLILTRpppeFIKHLQMTQNEDTRYEAQAALVKGW 156
Cdd:COG0596   86 LGLERVVLVGHSMGGMVALELAARHP-ERVAGLVLVDEVLAA----LAEPLRRPGLAPEALAALLRALART 151
Abhydrolase_6 pfam12697
Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse ...
26-258 7.93e-07

Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse specificity.


Pssm-ID: 463673 [Multi-domain]  Cd Length: 211  Bit Score: 48.62  E-value: 7.93e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 587732449   26 IVCLPGLGQDhrgYKYILPFLVGKYRVIRIVWKGHGDNREPMDKWsveDQASDTIALLDSL-QVQTFVPISHSHGGWCAM 104
Cdd:pfam12697   1 VVLVHGAGLS---AAPLAALLAAGVAVLAPDLPGHGSSSPPPLDL---ADLADLAALLDELgAARPVVLVGHSLGGAVAL 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 587732449  105 EMAARLGKERV---PAILLTDLIltRPPPEFIKHLqMTQNEDTRYEAQAALVKGWLDNTTNKNVLDYFHNDVGSHGfenw 181
Cdd:pfam12697  75 AAAAAALVVGVlvaPLAAPPGLL--AALLALLARL-GAALAAPAWLAAESLARGFLDDLPADAEWAAALARLAALL---- 147
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 587732449  182 shfcwlveknYERWGSPMERIETINDPPLIRhvfsHPRDEAYFAAHEEFARKHREWfSFARLNGESHFPVVElPEAV 258
Cdd:pfam12697 148 ----------AALALLPLAAWRDLPVPVLVL----AEEDRLVPELAQRLLAALAGA-RLVVLPGAGHLPLDD-PEEV 208
PRK10673 PRK10673
esterase;
46-123 5.61e-05

esterase;


Pssm-ID: 182637 [Multi-domain]  Cd Length: 255  Bit Score: 43.57  E-value: 5.61e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 587732449  46 LVGKYRVIRIVWKGHG-DNREP-MDkwsVEDQASDTIALLDSLQVQTFVPISHSHGGWCAMEMAArLGKERVPAILLTDL 123
Cdd:PRK10673  39 LVNDHDIIQVDMRNHGlSPRDPvMN---YPAMAQDLLDTLDALQIEKATFIGHSMGGKAVMALTA-LAPDRIDKLVAIDI 114
 
Name Accession Description Interval E-value
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
6-156 6.99e-21

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 88.13  E-value: 6.99e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 587732449   6 TINDVELSFDDRGmvSSEPTIVCLPGLGQDHRGYKYILPFLVGKYRVIRIVWKGHGDNREPMDKWSVEDQASDTIALLDS 85
Cdd:COG0596    8 TVDGVRLHYREAG--PDGPPVVLLHGLPGSSYEWRPLIPALAAGYRVIAPDLRGHGRSDKPAGGYTLDDLADDLAALLDA 85
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 587732449  86 LQVQTFVPISHSHGGWCAMEMAARLGkERVPAILLTDLILTRpppeFIKHLQMTQNEDTRYEAQAALVKGW 156
Cdd:COG0596   86 LGLERVVLVGHSMGGMVALELAARHP-ERVAGLVLVDEVLAA----LAEPLRRPGLAPEALAALLRALART 151
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
24-121 5.44e-07

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 49.23  E-value: 5.44e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 587732449  24 PTIVCLPGLGQDHRGYKYILPFLVGK-YRVIRIVWKGHGDN-REPMDKWSVEDQASDTIALLDSLQVQTFVPIS---HSH 98
Cdd:COG2267   29 GTVVLVHGLGEHSGRYAELAEALAAAgYAVLAFDLRGHGRSdGPRGHVDSFDDYVDDLRAALDALRARPGLPVVllgHSM 108
                         90       100
                 ....*....|....*....|...
gi 587732449  99 GGWCAMEMAARLGkERVPAILLT 121
Cdd:COG2267  109 GGLIALLYAARYP-DRVAGLVLL 130
Abhydrolase_6 pfam12697
Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse ...
26-258 7.93e-07

Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse specificity.


Pssm-ID: 463673 [Multi-domain]  Cd Length: 211  Bit Score: 48.62  E-value: 7.93e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 587732449   26 IVCLPGLGQDhrgYKYILPFLVGKYRVIRIVWKGHGDNREPMDKWsveDQASDTIALLDSL-QVQTFVPISHSHGGWCAM 104
Cdd:pfam12697   1 VVLVHGAGLS---AAPLAALLAAGVAVLAPDLPGHGSSSPPPLDL---ADLADLAALLDELgAARPVVLVGHSLGGAVAL 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 587732449  105 EMAARLGKERV---PAILLTDLIltRPPPEFIKHLqMTQNEDTRYEAQAALVKGWLDNTTNKNVLDYFHNDVGSHGfenw 181
Cdd:pfam12697  75 AAAAAALVVGVlvaPLAAPPGLL--AALLALLARL-GAALAAPAWLAAESLARGFLDDLPADAEWAAALARLAALL---- 147
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 587732449  182 shfcwlveknYERWGSPMERIETINDPPLIRhvfsHPRDEAYFAAHEEFARKHREWfSFARLNGESHFPVVElPEAV 258
Cdd:pfam12697 148 ----------AALALLPLAAWRDLPVPVLVL----AEEDRLVPELAQRLLAALAGA-RLVVLPGAGHLPLDD-PEEV 208
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
24-126 8.21e-07

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 49.04  E-value: 8.21e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 587732449   24 PTIVCLPGLGQDHRGYKYILPFLVGK-YRVIRIVWKGHGDNREPM--DKWSVEDQASDTIALLDSLQVQTFVPISHSHGG 100
Cdd:pfam00561   1 PPVLLLHGLPGSSDLWRKLAPALARDgFRVIALDLRGFGKSSRPKaqDDYRTDDLAEDLEYILEALGLEKVNLVGHSMGG 80
                          90       100
                  ....*....|....*....|....*.
gi 587732449  101 WCAMEMAARLgKERVPAILLTDLILT 126
Cdd:pfam00561  81 LIALAYAAKY-PDRVKALVLLGALDP 105
PRK10673 PRK10673
esterase;
46-123 5.61e-05

esterase;


Pssm-ID: 182637 [Multi-domain]  Cd Length: 255  Bit Score: 43.57  E-value: 5.61e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 587732449  46 LVGKYRVIRIVWKGHG-DNREP-MDkwsVEDQASDTIALLDSLQVQTFVPISHSHGGWCAMEMAArLGKERVPAILLTDL 123
Cdd:PRK10673  39 LVNDHDIIQVDMRNHGlSPRDPvMN---YPAMAQDLLDTLDALQIEKATFIGHSMGGKAVMALTA-LAPDRIDKLVAIDI 114
PRK14875 PRK14875
acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional
22-120 1.71e-04

acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional


Pssm-ID: 184875 [Multi-domain]  Cd Length: 371  Bit Score: 42.24  E-value: 1.71e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 587732449  22 SEPTIVCLPGLGQDHRGYKYILPFLVGKYRVIRIVWKGHGDNREPMDKWSVEDQASDTIALLDSLQVQTFVPISHSHGGW 101
Cdd:PRK14875 130 DGTPVVLIHGFGGDLNNWLFNHAALAAGRPVIALDLPGHGASSKAVGAGSLDELAAAVLAFLDALGIERAHLVGHSMGGA 209
                         90
                 ....*....|....*....
gi 587732449 102 CAMEMAARlGKERVPAILL 120
Cdd:PRK14875 210 VALRLAAR-APQRVASLTL 227
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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