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Conserved domains on  [gi|674222734|dbj|GAK62689|]
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indigoidine synthase A-like protein [Moesziomyces antarcticus]

Protein Classification

pseudouridine-5'-phosphate glycosidase family protein( domain architecture ID 10514971)

pseudouridine-5'-phosphate glycosidase containing a C-terminal ribokinase superfamily domain, may catalyze the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil, and/or the phosphorylation at a hydroxyl group of a wide variety of substrates including carbohydrates and aromatic small molecules

CATH:  3.40.1190.20|3.40.1790.10
EC:  4.2.1.70
Gene Ontology:  GO:0016310|GO:0005524|GO:0016301|GO:0004730|GO:0046872
PubMed:  8382990|23066817
SCOP:  4000759

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Indigoidine_A pfam04227
Indigoidine synthase A like protein; Indigoidine is a blue pigment synthesized by Erwinia ...
 29-328 2.64e-144

Indigoidine synthase A like protein; Indigoidine is a blue pigment synthesized by Erwinia chrysanthemi implicated in pathogenicity and protection from oxidative stress. IdgA is involved in indigoidine biosynthesis, but its specific function is unknown. The recommended name for this protein is now pseudouridine-5'-phosphate glycosidase.


:

Pssm-ID: 461231  Cd Length: 289  Bit Score: 424.11  E-value: 2.64e-144
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734   29 VRSALNpkTRAPVVALESTIITHGLPYPYNLEVAQELEQTVIDHGAVPATIALLDGKPLVGLDEPQLERLArcaidpsKN 108
Cdd:pfam04227   2 VAEALA--AGKPVVALESTIITHGLPYPQNLETALEVEAIVRENGAVPATIAILDGRPKVGLTDEELERLA-------DA 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734  109 TAIKASRRDIAHVLSKGHgsVGGTTVSGTMVLAHMAGVPIFATGGIGGVHRGAESTMDISADLTELGRTPVAVFCSGPKS 188
Cdd:pfam04227  73 GGAKVSRRDLAYVLALGL--DGGTTVAATMILAHLAGIRVFATGGIGGVHRGAEETMDISADLTELGRTPVAVVCAGVKS 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734  189 ILDIPRTLEVLETFGVSVTTFNpTGEFPAFYTSNSGLSVPY-AGTDAQAAAAIFANAQLGLQSGHVFANPIPSEWNEVGQ 267
Cdd:pfam04227 151 ILDIPRTLEYLETQGVPVVGYG-TDEFPAFYTRDSGFKSPYrVDSPEEAAAIIRAQWALGLGSGVLVANPIPEEHALDRE 229

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 674222734  268 RIQQSVEQAVRESVQQGIdkKGKEVTPWLLKRLAELIP-ESKKSNRALVVNNAKKAAQVAVE 328
Cdd:pfam04227 230 EIDAAIEQALAEAEEQGI--TGKAVTPFLLARIAELTGgKSLEANIALVKNNARLAAQIAVA 289
ribokinase_pfkB_like super family cl00192
ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including ...
 360-725 1.72e-35

ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase, 2-dehydro-3-deoxygluconokinase, 1-phosphofructokinase, the minor 6-phosphofructokinase (PfkB), inosine-guanosine kinase, and adenosine kinase. Even though there is a high degree of structural conservation within this superfamily, their multimerization level varies widely, monomeric (e.g. adenosine kinase), dimeric (e.g. ribokinase), and trimeric (e.g THZ kinase).


The actual alignment was detected with superfamily member cd01941:

Pssm-ID: 469648 [Multi-domain]  Cd Length: 288  Bit Score: 135.90  E-value: 1.72e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734 360 ILIFGAAAVDITSQTQSagtaSKLAATTYPGRVSITLGGVARNMAETATRILsplhtrstpSPVKLVTPHGDDDFGLLLR 439
Cdd:cd01941    2 IVVIGAANIDLRGKVSG----SLVPGTSNPGHVKQSPGGVGRNIAENLARLG---------VSVALLSAVGDDSEGESIL 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734 440 TGLEHAGMRTDGLFVPsgNHRTAVCSLMIDDSGDLISGVADMDIGKaaLTSTSTSVDVKSLLEFEAPrfVVFDGNIGQAH 519
Cdd:cd01941   69 EESEKAGLNVRGIVFE--GRSTASYTAILDKDGDLVVALADMDIYE--LLTPDFLRKIREALKEAKP--IVVDANLPEEA 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734 520 ADELLKACRAYNassetvrgsrpaVLTVFEPTSVAKsvtvLSHFAAAAADgtkkqpISFTTPNAVELDRIHAAALDyGLV 599
Cdd:cd01941  143 LEYLLALAAKHG------------VPVAFEPTSAPK----LKKLFYLLHA------IDLLTPNRAELEALAGALIE-NNE 199

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734 600 DPTKIQPTRLASSVpssvlpqtvldkahdlvqagifKTVLLKVGRHGVVTIDASRAQ-HHPVPAGKVE-VVNTTGCGDSF 677
Cdd:cd01941  200 DENKAAKILLLPGI----------------------KNVIVTLGAKGVLLSSREGGVeTKLFPAPQPEtVVNVTGAGDAF 257

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*...
gi 674222734 678 AGAFAASLFHllaqsqgtravagrsspGDQLDLAVRVGQLAARRTLIS 725
Cdd:cd01941  258 VAGLVAGLLE-----------------GMSLDDSLRFAQAAAALTLES 288
 
Name Accession Description Interval E-value
Indigoidine_A pfam04227
Indigoidine synthase A like protein; Indigoidine is a blue pigment synthesized by Erwinia ...
 29-328 2.64e-144

Indigoidine synthase A like protein; Indigoidine is a blue pigment synthesized by Erwinia chrysanthemi implicated in pathogenicity and protection from oxidative stress. IdgA is involved in indigoidine biosynthesis, but its specific function is unknown. The recommended name for this protein is now pseudouridine-5'-phosphate glycosidase.


Pssm-ID: 461231  Cd Length: 289  Bit Score: 424.11  E-value: 2.64e-144
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734   29 VRSALNpkTRAPVVALESTIITHGLPYPYNLEVAQELEQTVIDHGAVPATIALLDGKPLVGLDEPQLERLArcaidpsKN 108
Cdd:pfam04227   2 VAEALA--AGKPVVALESTIITHGLPYPQNLETALEVEAIVRENGAVPATIAILDGRPKVGLTDEELERLA-------DA 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734  109 TAIKASRRDIAHVLSKGHgsVGGTTVSGTMVLAHMAGVPIFATGGIGGVHRGAESTMDISADLTELGRTPVAVFCSGPKS 188
Cdd:pfam04227  73 GGAKVSRRDLAYVLALGL--DGGTTVAATMILAHLAGIRVFATGGIGGVHRGAEETMDISADLTELGRTPVAVVCAGVKS 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734  189 ILDIPRTLEVLETFGVSVTTFNpTGEFPAFYTSNSGLSVPY-AGTDAQAAAAIFANAQLGLQSGHVFANPIPSEWNEVGQ 267
Cdd:pfam04227 151 ILDIPRTLEYLETQGVPVVGYG-TDEFPAFYTRDSGFKSPYrVDSPEEAAAIIRAQWALGLGSGVLVANPIPEEHALDRE 229

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 674222734  268 RIQQSVEQAVRESVQQGIdkKGKEVTPWLLKRLAELIP-ESKKSNRALVVNNAKKAAQVAVE 328
Cdd:pfam04227 230 EIDAAIEQALAEAEEQGI--TGKAVTPFLLARIAELTGgKSLEANIALVKNNARLAAQIAVA 289
PsuG COG2313
Pseudouridine-5'-phosphate glycosidase (pseudoU degradation) [Nucleotide transport and ...
 20-332 2.54e-131

Pseudouridine-5'-phosphate glycosidase (pseudoU degradation) [Nucleotide transport and metabolism];


Pssm-ID: 441887  Cd Length: 303  Bit Score: 391.00  E-value: 2.54e-131
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734  20 HPTLALSPAVRSALnpKTRAPVVALESTIITHGLPYPYNLEVAQELEQTVIDHGAVPATIALLDGKPLVGLDEPQLERLA 99
Cdd:COG2313    1 NKYLRISPEVAAAL--AAGRPVVALESTIISHGMPYPQNLETAREVEAIVREAGAVPATIAVLDGKIKVGLSDEELERLA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734 100 RcaidpSKNtAIKASRRDIAHVLSKGhgSVGGTTVSGTMVLAHMAGVPIFATGGIGGVHRGAESTMDISADLTELGRTPV 179
Cdd:COG2313   79 Q-----AKD-VAKVSRRDLPVALARG--RSGATTVAATMILAALAGIRVFATGGIGGVHRGAEETFDISADLQELARTPV 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734 180 AVFCSGPKSILDIPRTLEVLETFGVSVTTFNpTGEFPAFYTSNSGLSVPY-AGTDAQAAAAIFANAQLGLQSGHVFANPI 258
Cdd:COG2313  151 AVVCAGAKSILDLPLTLEYLETLGVPVIGYG-TDEFPAFYSRSSGLPVPYrVDSPEEIAAILRAKWALGLPGGVLVANPI 229

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 674222734 259 PSEWNEVGQRIQQSVEQAVRESVQQGIdkKGKEVTPWLLKRLAELIP-ESKKSNRALVVNNAKKAAQVAVELNRI 332
Cdd:COG2313  230 PEEDALDAEEIDAAIAEALAEAEAQGI--RGKAVTPFLLARIAELTGgRSLEANIALVKNNARLAAEIAVALAAL 302
YeiC_kinase_like cd01941
YeiC-like sugar kinase. Found in eukaryotes and bacteria, YeiC-like kinase is part of the ...
 360-725 1.72e-35

YeiC-like sugar kinase. Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time.


Pssm-ID: 238916 [Multi-domain]  Cd Length: 288  Bit Score: 135.90  E-value: 1.72e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734 360 ILIFGAAAVDITSQTQSagtaSKLAATTYPGRVSITLGGVARNMAETATRILsplhtrstpSPVKLVTPHGDDDFGLLLR 439
Cdd:cd01941    2 IVVIGAANIDLRGKVSG----SLVPGTSNPGHVKQSPGGVGRNIAENLARLG---------VSVALLSAVGDDSEGESIL 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734 440 TGLEHAGMRTDGLFVPsgNHRTAVCSLMIDDSGDLISGVADMDIGKaaLTSTSTSVDVKSLLEFEAPrfVVFDGNIGQAH 519
Cdd:cd01941   69 EESEKAGLNVRGIVFE--GRSTASYTAILDKDGDLVVALADMDIYE--LLTPDFLRKIREALKEAKP--IVVDANLPEEA 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734 520 ADELLKACRAYNassetvrgsrpaVLTVFEPTSVAKsvtvLSHFAAAAADgtkkqpISFTTPNAVELDRIHAAALDyGLV 599
Cdd:cd01941  143 LEYLLALAAKHG------------VPVAFEPTSAPK----LKKLFYLLHA------IDLLTPNRAELEALAGALIE-NNE 199

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734 600 DPTKIQPTRLASSVpssvlpqtvldkahdlvqagifKTVLLKVGRHGVVTIDASRAQ-HHPVPAGKVE-VVNTTGCGDSF 677
Cdd:cd01941  200 DENKAAKILLLPGI----------------------KNVIVTLGAKGVLLSSREGGVeTKLFPAPQPEtVVNVTGAGDAF 257

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*...
gi 674222734 678 AGAFAASLFHllaqsqgtravagrsspGDQLDLAVRVGQLAARRTLIS 725
Cdd:cd01941  258 VAGLVAGLLE-----------------GMSLDDSLRFAQAAAALTLES 288
RbsK COG0524
Sugar or nucleoside kinase, ribokinase family [Carbohydrate transport and metabolism]; Sugar ...
 360-685 1.28e-20

Sugar or nucleoside kinase, ribokinase family [Carbohydrate transport and metabolism]; Sugar or nucleoside kinase, ribokinase family is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 440290 [Multi-domain]  Cd Length: 301  Bit Score: 93.03  E-value: 1.28e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734 360 ILIFGAAAVDITSQTQSAGTASKLAATtypGRVSITLGGVARNMAETATRiLSplhtrstpSPVKLVTPHGDDDFGLLLR 439
Cdd:COG0524    2 VLVIGEALVDLVARVDRLPKGGETVLA---GSFRRSPGGAAANVAVALAR-LG--------ARVALVGAVGDDPFGDFLL 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734 440 TGLEHAGMRTDGLFVpSGNHRTAVCSLMIDDSGD---LISGVADMDIGKAALtststsvdvkSLLEFEAPRFVVFDG--- 513
Cdd:COG0524   70 AELRAEGVDTSGVRR-DPGAPTGLAFILVDPDGErtiVFYRGANAELTPEDL----------DEALLAGADILHLGGitl 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734 514 --NIGQAHADELLKACRAYNassetvrgsrpaVLTVFEPTSVAKSVTVLSHFAAAAADGtkkqpISFTTPNAVELDRIha 591
Cdd:COG0524  139 asEPPREALLAALEAARAAG------------VPVSLDPNYRPALWEPARELLRELLAL-----VDILFPNEEEAELL-- 199

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734 592 aaldYGLVDPTKIqptrlassvpssvlpqtvldkAHDLVQAGIfKTVLLKVGRHGVVTIDASRAQHhpVPAGKVEVVNTT 671
Cdd:COG0524  200 ----TGETDPEEA---------------------AAALLARGV-KLVVVTLGAEGALLYTGGEVVH--VPAFPVEVVDTT 251

                        330
                 ....*....|....
gi 674222734 672 GCGDSFAGAFAASL 685
Cdd:COG0524  252 GAGDAFAAGFLAGL 265
PfkB pfam00294
pfkB family carbohydrate kinase; This family includes a variety of carbohydrate and pyrimidine ...
 366-685 1.82e-14

pfkB family carbohydrate kinase; This family includes a variety of carbohydrate and pyrimidine kinases.


Pssm-ID: 425587 [Multi-domain]  Cd Length: 294  Bit Score: 74.69  E-value: 1.82e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734  366 AAVDITSQTQSAGTASKLAATTYPGRVSITLGGVARNMAetatRILSPLHTRSTpspvkLVTPHGDDDFGLLLRTGLEHA 445
Cdd:pfam00294   3 VVIGEANIDLIGNVEGLPGELVRVSTVEKGPGGKGANVA----VALARLGGDVA-----FIGAVGDDNFGEFLLQELKKE 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734  446 GMRTDGLfVPSGNHRTAVCSLMIDDSGDLISGVADMDIGKAaltstSTSVDVKSLLEFEAPRFVVFDG----NIGQAHAD 521
Cdd:pfam00294  74 GVDTDYV-VIDEDTRTGTALIEVDGDGERTIVFNRGAAADL-----TPEELEENEDLLENADLLYISGslplGLPEATLE 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734  522 ELLKACRAynassetvrgSRPAVLTVFEPTSVAKSVtvLSHFAAAAadgtkkqpiSFTTPNAVELDRIhaaaldYGLVDP 601
Cdd:pfam00294 148 ELIEAAKN----------GGTFDPNLLDPLGAAREA--LLELLPLA---------DLLKPNEEELEAL------TGAKLD 200

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734  602 TkiqptrlassvpssvlPQTVLDKAHDLVQAGIfKTVLLKVGRHGVVTIDASRAQHHPvPAGKVEVVNTTGCGDSFAGAF 681
Cdd:pfam00294 201 D----------------IEEALAALHKLLAKGI-KTVIVTLGADGALVVEGDGEVHVP-AVPKVKVVDTTGAGDSFVGGF 262


                  ....
gi 674222734  682 AASL 685
Cdd:pfam00294 263 LAGL 266
PRK09850 PRK09850
pseudouridine kinase; Provisional
 360-683 3.63e-08

pseudouridine kinase; Provisional


Pssm-ID: 182111 [Multi-domain]  Cd Length: 313  Bit Score: 55.76  E-value: 3.63e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734 360 ILIFGAAAVDITSQTQsagtASKLAATTYPGRVSITLGGVARNMAETatriLSPLHTRSTpspvkLVTPHGDDDFGLLLR 439
Cdd:PRK09850   7 VVIIGSANIDVAGYSH----ESLNYADSNPGKIKFTPGGVGRNIAQN----LALLGNKAW-----LLSAVGSDFYGQSLL 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734 440 TGLEHAGMRTDGLFVPSGNHRTAVCSLMiDDSGDLISGVADMDIgkaalTSTSTSVDVKSLLEF-EAPRFVVFDGNIGQA 518
Cdd:PRK09850  74 TQTNQSGVYVDKCLIVPGENTSSYLSLL-DNTGEMLVAINDMNI-----SNAITAEYLAQHREFiQRAKVIVADCNISEE 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734 519 HADELLKacrayNAssetvrGSRPavltVF-EPTSVAKSVTVLSHFAAaaadgtkkqpISFTTPNAVELDRIHAAALDyG 597
Cdd:PRK09850 148 ALAWILD-----NA------ANVP----VFvDPVSAWKCVKVRDRLNQ----------IHTLKPNRLEAETLSGIALS-G 201

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734 598 LVDPTKIqptrlassvpssvlpqtvldkAHDLVQAGIFKTVlLKVGRHGVVTIDASRAQHHPVPAgKVEVVNTTGCGDSF 677
Cdd:PRK09850 202 REDVAKV---------------------AAWFHQHGLNRLV-LSMGGDGVYYSDISGESGWSAPI-KTNVINVTGAGDAM 258


                 ....*.
gi 674222734 678 AGAFAA 683
Cdd:PRK09850 259 MAGLAS 264
 
Name Accession Description Interval E-value
Indigoidine_A pfam04227
Indigoidine synthase A like protein; Indigoidine is a blue pigment synthesized by Erwinia ...
 29-328 2.64e-144

Indigoidine synthase A like protein; Indigoidine is a blue pigment synthesized by Erwinia chrysanthemi implicated in pathogenicity and protection from oxidative stress. IdgA is involved in indigoidine biosynthesis, but its specific function is unknown. The recommended name for this protein is now pseudouridine-5'-phosphate glycosidase.


Pssm-ID: 461231  Cd Length: 289  Bit Score: 424.11  E-value: 2.64e-144
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734   29 VRSALNpkTRAPVVALESTIITHGLPYPYNLEVAQELEQTVIDHGAVPATIALLDGKPLVGLDEPQLERLArcaidpsKN 108
Cdd:pfam04227   2 VAEALA--AGKPVVALESTIITHGLPYPQNLETALEVEAIVRENGAVPATIAILDGRPKVGLTDEELERLA-------DA 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734  109 TAIKASRRDIAHVLSKGHgsVGGTTVSGTMVLAHMAGVPIFATGGIGGVHRGAESTMDISADLTELGRTPVAVFCSGPKS 188
Cdd:pfam04227  73 GGAKVSRRDLAYVLALGL--DGGTTVAATMILAHLAGIRVFATGGIGGVHRGAEETMDISADLTELGRTPVAVVCAGVKS 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734  189 ILDIPRTLEVLETFGVSVTTFNpTGEFPAFYTSNSGLSVPY-AGTDAQAAAAIFANAQLGLQSGHVFANPIPSEWNEVGQ 267
Cdd:pfam04227 151 ILDIPRTLEYLETQGVPVVGYG-TDEFPAFYTRDSGFKSPYrVDSPEEAAAIIRAQWALGLGSGVLVANPIPEEHALDRE 229

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 674222734  268 RIQQSVEQAVRESVQQGIdkKGKEVTPWLLKRLAELIP-ESKKSNRALVVNNAKKAAQVAVE 328
Cdd:pfam04227 230 EIDAAIEQALAEAEEQGI--TGKAVTPFLLARIAELTGgKSLEANIALVKNNARLAAQIAVA 289
PsuG COG2313
Pseudouridine-5'-phosphate glycosidase (pseudoU degradation) [Nucleotide transport and ...
 20-332 2.54e-131

Pseudouridine-5'-phosphate glycosidase (pseudoU degradation) [Nucleotide transport and metabolism];


Pssm-ID: 441887  Cd Length: 303  Bit Score: 391.00  E-value: 2.54e-131
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734  20 HPTLALSPAVRSALnpKTRAPVVALESTIITHGLPYPYNLEVAQELEQTVIDHGAVPATIALLDGKPLVGLDEPQLERLA 99
Cdd:COG2313    1 NKYLRISPEVAAAL--AAGRPVVALESTIISHGMPYPQNLETAREVEAIVREAGAVPATIAVLDGKIKVGLSDEELERLA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734 100 RcaidpSKNtAIKASRRDIAHVLSKGhgSVGGTTVSGTMVLAHMAGVPIFATGGIGGVHRGAESTMDISADLTELGRTPV 179
Cdd:COG2313   79 Q-----AKD-VAKVSRRDLPVALARG--RSGATTVAATMILAALAGIRVFATGGIGGVHRGAEETFDISADLQELARTPV 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734 180 AVFCSGPKSILDIPRTLEVLETFGVSVTTFNpTGEFPAFYTSNSGLSVPY-AGTDAQAAAAIFANAQLGLQSGHVFANPI 258
Cdd:COG2313  151 AVVCAGAKSILDLPLTLEYLETLGVPVIGYG-TDEFPAFYSRSSGLPVPYrVDSPEEIAAILRAKWALGLPGGVLVANPI 229

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 674222734 259 PSEWNEVGQRIQQSVEQAVRESVQQGIdkKGKEVTPWLLKRLAELIP-ESKKSNRALVVNNAKKAAQVAVELNRI 332
Cdd:COG2313  230 PEEDALDAEEIDAAIAEALAEAEAQGI--RGKAVTPFLLARIAELTGgRSLEANIALVKNNARLAAEIAVALAAL 302
YeiC_kinase_like cd01941
YeiC-like sugar kinase. Found in eukaryotes and bacteria, YeiC-like kinase is part of the ...
 360-725 1.72e-35

YeiC-like sugar kinase. Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time.


Pssm-ID: 238916 [Multi-domain]  Cd Length: 288  Bit Score: 135.90  E-value: 1.72e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734 360 ILIFGAAAVDITSQTQSagtaSKLAATTYPGRVSITLGGVARNMAETATRILsplhtrstpSPVKLVTPHGDDDFGLLLR 439
Cdd:cd01941    2 IVVIGAANIDLRGKVSG----SLVPGTSNPGHVKQSPGGVGRNIAENLARLG---------VSVALLSAVGDDSEGESIL 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734 440 TGLEHAGMRTDGLFVPsgNHRTAVCSLMIDDSGDLISGVADMDIGKaaLTSTSTSVDVKSLLEFEAPrfVVFDGNIGQAH 519
Cdd:cd01941   69 EESEKAGLNVRGIVFE--GRSTASYTAILDKDGDLVVALADMDIYE--LLTPDFLRKIREALKEAKP--IVVDANLPEEA 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734 520 ADELLKACRAYNassetvrgsrpaVLTVFEPTSVAKsvtvLSHFAAAAADgtkkqpISFTTPNAVELDRIHAAALDyGLV 599
Cdd:cd01941  143 LEYLLALAAKHG------------VPVAFEPTSAPK----LKKLFYLLHA------IDLLTPNRAELEALAGALIE-NNE 199

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734 600 DPTKIQPTRLASSVpssvlpqtvldkahdlvqagifKTVLLKVGRHGVVTIDASRAQ-HHPVPAGKVE-VVNTTGCGDSF 677
Cdd:cd01941  200 DENKAAKILLLPGI----------------------KNVIVTLGAKGVLLSSREGGVeTKLFPAPQPEtVVNVTGAGDAF 257

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*...
gi 674222734 678 AGAFAASLFHllaqsqgtravagrsspGDQLDLAVRVGQLAARRTLIS 725
Cdd:cd01941  258 VAGLVAGLLE-----------------GMSLDDSLRFAQAAAALTLES 288
RbsK COG0524
Sugar or nucleoside kinase, ribokinase family [Carbohydrate transport and metabolism]; Sugar ...
 360-685 1.28e-20

Sugar or nucleoside kinase, ribokinase family [Carbohydrate transport and metabolism]; Sugar or nucleoside kinase, ribokinase family is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 440290 [Multi-domain]  Cd Length: 301  Bit Score: 93.03  E-value: 1.28e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734 360 ILIFGAAAVDITSQTQSAGTASKLAATtypGRVSITLGGVARNMAETATRiLSplhtrstpSPVKLVTPHGDDDFGLLLR 439
Cdd:COG0524    2 VLVIGEALVDLVARVDRLPKGGETVLA---GSFRRSPGGAAANVAVALAR-LG--------ARVALVGAVGDDPFGDFLL 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734 440 TGLEHAGMRTDGLFVpSGNHRTAVCSLMIDDSGD---LISGVADMDIGKAALtststsvdvkSLLEFEAPRFVVFDG--- 513
Cdd:COG0524   70 AELRAEGVDTSGVRR-DPGAPTGLAFILVDPDGErtiVFYRGANAELTPEDL----------DEALLAGADILHLGGitl 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734 514 --NIGQAHADELLKACRAYNassetvrgsrpaVLTVFEPTSVAKSVTVLSHFAAAAADGtkkqpISFTTPNAVELDRIha 591
Cdd:COG0524  139 asEPPREALLAALEAARAAG------------VPVSLDPNYRPALWEPARELLRELLAL-----VDILFPNEEEAELL-- 199

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734 592 aaldYGLVDPTKIqptrlassvpssvlpqtvldkAHDLVQAGIfKTVLLKVGRHGVVTIDASRAQHhpVPAGKVEVVNTT 671
Cdd:COG0524  200 ----TGETDPEEA---------------------AAALLARGV-KLVVVTLGAEGALLYTGGEVVH--VPAFPVEVVDTT 251

                        330
                 ....*....|....
gi 674222734 672 GCGDSFAGAFAASL 685
Cdd:COG0524  252 GAGDAFAAGFLAGL 265
ribokinase cd01174
Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This ...
 359-685 1.18e-15

Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides and histidine, and for entry into the pentose phosphate pathway. Ribokinase is dimeric in solution.


Pssm-ID: 238579 [Multi-domain]  Cd Length: 292  Bit Score: 77.98  E-value: 1.18e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734 359 GILIFGAAAVDITSQTQ---SAG-TaskLAATTYpgrvSITLGGVARNMAETATRiLSplhtrstpSPVKLVTPHGDDDF 434
Cdd:cd01174    1 KVVVVGSINVDLVTRVDrlpKPGeT---VLGSSF----ETGPGGKGANQAVAAAR-LG--------ARVAMIGAVGDDAF 64

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734 435 GLLLRTGLEHAGMRTDGLFVPSGNHrTAVCSLMIDDSGD---LISGVADMDIgkaaltstsTSVDVKSLLE-FEAPRFVV 510
Cdd:cd01174   65 GDELLENLREEGIDVSYVEVVVGAP-TGTAVITVDESGEnriVVVPGANGEL---------TPADVDAALElIAAADVLL 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734 511 FDGNIGQAHADELLKACRaynassetvrgsRPAVLTVFEPTSVAKsvtvLSHFAAAAADgtkkqpisFTTPNAVEldrih 590
Cdd:cd01174  135 LQLEIPLETVLAALRAAR------------RAGVTVILNPAPARP----LPAELLALVD--------ILVPNETE----- 185

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734 591 AAALdyglvdpTKIQPTRLASSvpssvlpqtvlDKAHDLVQAGIFKTVLLKVGRHGVVTIDASRAQHhpVPAGKVEVVNT 670
Cdd:cd01174  186 AALL-------TGIEVTDEEDA-----------EKAARLLLAKGVKNVIVTLGAKGALLASGGEVEH--VPAFKVKAVDT 245

                        330
                 ....*....|....*
gi 674222734 671 TGCGDSFAGAFAASL 685
Cdd:cd01174  246 TGAGDTFIGALAAAL 260
PfkB pfam00294
pfkB family carbohydrate kinase; This family includes a variety of carbohydrate and pyrimidine ...
 366-685 1.82e-14

pfkB family carbohydrate kinase; This family includes a variety of carbohydrate and pyrimidine kinases.


Pssm-ID: 425587 [Multi-domain]  Cd Length: 294  Bit Score: 74.69  E-value: 1.82e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734  366 AAVDITSQTQSAGTASKLAATTYPGRVSITLGGVARNMAetatRILSPLHTRSTpspvkLVTPHGDDDFGLLLRTGLEHA 445
Cdd:pfam00294   3 VVIGEANIDLIGNVEGLPGELVRVSTVEKGPGGKGANVA----VALARLGGDVA-----FIGAVGDDNFGEFLLQELKKE 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734  446 GMRTDGLfVPSGNHRTAVCSLMIDDSGDLISGVADMDIGKAaltstSTSVDVKSLLEFEAPRFVVFDG----NIGQAHAD 521
Cdd:pfam00294  74 GVDTDYV-VIDEDTRTGTALIEVDGDGERTIVFNRGAAADL-----TPEELEENEDLLENADLLYISGslplGLPEATLE 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734  522 ELLKACRAynassetvrgSRPAVLTVFEPTSVAKSVtvLSHFAAAAadgtkkqpiSFTTPNAVELDRIhaaaldYGLVDP 601
Cdd:pfam00294 148 ELIEAAKN----------GGTFDPNLLDPLGAAREA--LLELLPLA---------DLLKPNEEELEAL------TGAKLD 200

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734  602 TkiqptrlassvpssvlPQTVLDKAHDLVQAGIfKTVLLKVGRHGVVTIDASRAQHHPvPAGKVEVVNTTGCGDSFAGAF 681
Cdd:pfam00294 201 D----------------IEEALAALHKLLAKGI-KTVIVTLGADGALVVEGDGEVHVP-AVPKVKVVDTTGAGDSFVGGF 262


                  ....
gi 674222734  682 AASL 685
Cdd:pfam00294 263 LAGL 266
PRK09850 PRK09850
pseudouridine kinase; Provisional
 360-683 3.63e-08

pseudouridine kinase; Provisional


Pssm-ID: 182111 [Multi-domain]  Cd Length: 313  Bit Score: 55.76  E-value: 3.63e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734 360 ILIFGAAAVDITSQTQsagtASKLAATTYPGRVSITLGGVARNMAETatriLSPLHTRSTpspvkLVTPHGDDDFGLLLR 439
Cdd:PRK09850   7 VVIIGSANIDVAGYSH----ESLNYADSNPGKIKFTPGGVGRNIAQN----LALLGNKAW-----LLSAVGSDFYGQSLL 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734 440 TGLEHAGMRTDGLFVPSGNHRTAVCSLMiDDSGDLISGVADMDIgkaalTSTSTSVDVKSLLEF-EAPRFVVFDGNIGQA 518
Cdd:PRK09850  74 TQTNQSGVYVDKCLIVPGENTSSYLSLL-DNTGEMLVAINDMNI-----SNAITAEYLAQHREFiQRAKVIVADCNISEE 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734 519 HADELLKacrayNAssetvrGSRPavltVF-EPTSVAKSVTVLSHFAAaaadgtkkqpISFTTPNAVELDRIHAAALDyG 597
Cdd:PRK09850 148 ALAWILD-----NA------ANVP----VFvDPVSAWKCVKVRDRLNQ----------IHTLKPNRLEAETLSGIALS-G 201

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734 598 LVDPTKIqptrlassvpssvlpqtvldkAHDLVQAGIFKTVlLKVGRHGVVTIDASRAQHHPVPAgKVEVVNTTGCGDSF 677
Cdd:PRK09850 202 REDVAKV---------------------AAWFHQHGLNRLV-LSMGGDGVYYSDISGESGWSAPI-KTNVINVTGAGDAM 258


                 ....*.
gi 674222734 678 AGAFAA 683
Cdd:PRK09850 259 MAGLAS 264
ribokinase_pfkB_like cd00287
ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including ...
 609-686 2.19e-07

ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase, 2-dehydro-3-deoxygluconokinase, 1-phosphofructokinase, the minor 6-phosphofructokinase (PfkB), inosine-guanosine kinase, and adenosine kinase. Even though there is a high degree of structural conservation within this superfamily, their multimerization level varies widely, monomeric (e.g. adenosine kinase), dimeric (e.g. ribokinase), and trimeric (e.g THZ kinase).


Pssm-ID: 238177 [Multi-domain]  Cd Length: 196  Bit Score: 51.71  E-value: 2.19e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 674222734 609 LASSVPSSVLPQTVLDKAHDLVQAGIFKTVLLKVGRHGVVtIDASRAQHHPVPAGKVEVVNTTGCGDSFAGAFAASLF 686
Cdd:cd00287  120 AEALTGRRDLEVKEAAEAAALLLSKGPKVVIVTLGEKGAI-VATRGGTEVHVPAFPVKVVDTTGAGDAFLAALAAGLA 196
KdgK cd01166
2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form ...
 635-719 4.96e-07

2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the glycolysis and therefore use polymers, like pectin and xylan as carbon sources.


Pssm-ID: 238571 [Multi-domain]  Cd Length: 294  Bit Score: 52.19  E-value: 4.96e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734 635 FKTVLLKVGRHGVVTIDASRAQHhpVPAGKVEVVNTTGCGDSFAGAFAASLfhllaqsqgtraVAGrSSPGDQLDLAVRV 714
Cdd:cd01166  219 VKAVVVKLGAEGALVYTGGGRVF--VPAYPVEVVDTTGAGDAFAAGFLAGL------------LEG-WDLEEALRFANAA 283


                 ....*
gi 674222734 715 GQLAA 719
Cdd:cd01166  284 AALVV 288
FruK COG1105
1-phosphofructokinase or 6-phosphofructokinase II [Carbohydrate transport and metabolism];
619-685 6.86e-07

1-phosphofructokinase or 6-phosphofructokinase II [Carbohydrate transport and metabolism];


Pssm-ID: 440722 [Multi-domain]  Cd Length: 304  Bit Score: 51.67  E-value: 6.86e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 674222734 619 PQTVLDKAHDLVQAGIfKTVLLKVGRHGVVTIDASRAQHHPVPagKVEVVNTTGCGDSFAGAFAASL 685
Cdd:COG1105  199 LEDIIAAARELLERGA-ENVVVSLGADGALLVTEDGVYRAKPP--KVEVVSTVGAGDSMVAGFLAGL 262
PLN02341 PLN02341
pfkB-type carbohydrate kinase family protein
 636-690 1.85e-05

pfkB-type carbohydrate kinase family protein


Pssm-ID: 215195 [Multi-domain]  Cd Length: 470  Bit Score: 47.90  E-value: 1.85e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 674222734 636 KTVLLKVGRHGVVTIdaSRAQHHPVPAGKVEVVNTTGCGDSFAGAFAASLFHLLA 690
Cdd:PLN02341 320 KWVVVKMGSKGSILV--TRSSVSCAPAFKVNVVDTVGCGDSFAAAIALGYIHNLP 372
adenosine_kinase cd01168
Adenosine kinase (AK) catalyzes the phosphorylation of ribofuranosyl-containing nucleoside ...
 636-720 3.58e-05

Adenosine kinase (AK) catalyzes the phosphorylation of ribofuranosyl-containing nucleoside analogues at the 5'-hydroxyl using ATP or GTP as the phosphate donor.The physiological function of AK is associated with the regulation of extracellular adenosine levels and the preservation of intracellular adenylate pools. Adenosine kinase is involved in the purine salvage pathway.


Pssm-ID: 238573 [Multi-domain]  Cd Length: 312  Bit Score: 46.45  E-value: 3.58e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734 636 KTVLLKVGRHGVVTIDasRAQHHPVPA-GKVEVVNTTGCGDSFAGAFAASLfhllaqsqgtraVAGRSspgdqLDLAVRV 714
Cdd:cd01168  235 RIVVITQGAKGAVVVE--GGEVYPVPAiPVEKIVDTNGAGDAFAGGFLYGL------------VQGEP-----LEECIRL 295


                 ....*.
gi 674222734 715 GQLAAR 720
Cdd:cd01168  296 GSYAAA 301
FruK_PfkB_like cd01164
1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. ...
 591-685 1.18e-04

1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose 6-phosphate pathway, which responsible for breakdown of the galactose moiety during lactose metabolism by bacteria such as L. lactis.


Pssm-ID: 238570 [Multi-domain]  Cd Length: 289  Bit Score: 44.83  E-value: 1.18e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734 591 AAALDYGlvdPTKIQPTR--LASSVPSSVLPQT-VLDKAHDLVQAGIfKTVLLKVGRHGVVTIDASRAQHhpVPAGKVEV 667
Cdd:cd01164  171 LAALAAK---PFLIKPNReeLEELFGRPLGDEEdVIAAARKLIERGA-ENVLVSLGADGALLVTKDGVYR--ASPPKVKV 244

                         90
                 ....*....|....*...
gi 674222734 668 VNTTGCGDSFAGAFAASL 685
Cdd:cd01164  245 VSTVGAGDSMVAGFVAGL 262
Guanosine_kinase_like cd01947
Guanosine kinase-like sugar kinases. Found in bacteria and archaea, the guanosine kinase-like ...
 625-687 1.50e-04

Guanosine kinase-like sugar kinases. Found in bacteria and archaea, the guanosine kinase-like group is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time.


Pssm-ID: 238922 [Multi-domain]  Cd Length: 265  Bit Score: 44.33  E-value: 1.50e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 674222734 625 KAHDLVQAGIF-KTVLLKVGRHGVVTIDASRAQHhpVPAGKVEVVNTTGCGDSFAGAFAASLFH 687
Cdd:cd01947  179 LVVAEKIAGPFpRYLIVTEGELGAILYPGGRYNH--VPAKKAKVPDSTGAGDSFAAGFIYGLLK 240
PRK09434 PRK09434
aminoimidazole riboside kinase; Provisional
 636-718 1.57e-04

aminoimidazole riboside kinase; Provisional


Pssm-ID: 236514 [Multi-domain]  Cd Length: 304  Bit Score: 44.54  E-value: 1.57e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734 636 KTVLLKVGRHGVVTIDASRAQHhpVPAGKVEVVNTTGCGDsfagAFAASLFHLLAQsqgtravAGRSSPGDQL----DLA 711
Cdd:PRK09434 214 ALLLVTLGAEGVLVHTRGQVQH--FPAPSVDPVDTTGAGD----AFVAGLLAGLSQ-------AGLWTDEAELaeiiAQA 280


                 ....*..
gi 674222734 712 VRVGQLA 718
Cdd:PRK09434 281 QACGALA 287
ribokinase_group_B cd01945
Ribokinase-like subgroup B. Found in bacteria and plants, this subgroup is part of the ...
 643-697 2.25e-04

Ribokinase-like subgroup B. Found in bacteria and plants, this subgroup is part of the ribokinase/pfkB superfamily. Its oligomerization state is unknown at this time. .


Pssm-ID: 238920 [Multi-domain]  Cd Length: 284  Bit Score: 43.82  E-value: 2.25e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 674222734 643 GRHGVVTIDASRAQHHpVPAGKVEVVNTTGCGDSFAGAFAaslfHLLAQSQGTRA 697
Cdd:cd01945  211 GEAGCLWLERDGELFH-VPAFPVEVVDTTGAGDVFHGAFA----HALAEGMPLRE 260
ribokinase_group_A cd01942
Ribokinase-like subgroup A. Found in bacteria and archaea, this subgroup is part of the ...
 636-681 4.13e-04

Ribokinase-like subgroup A. Found in bacteria and archaea, this subgroup is part of the ribokinase/pfkB superfamily. Its oligomerization state is unknown at this time.


Pssm-ID: 238917 [Multi-domain]  Cd Length: 279  Bit Score: 43.07  E-value: 4.13e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 674222734 636 KTVLLKVGRHGVVTIDASRAQHHPvPAGKVEVVNTTGCGDSFAGAF 681
Cdd:cd01942  204 RVVVVTLGPKGAIVFEDGEEVEVP-AVPAVKVVDTTGAGDAFRAGF 248
ribokinase_group_D cd01937
Ribokinase-like subgroup D. Found in bacteria and archaea, this subgroup is part of the ...
 614-685 5.32e-04

Ribokinase-like subgroup D. Found in bacteria and archaea, this subgroup is part of the ribokinase/pfkB superfamily. Its oligomerization state is unknown at this time.


Pssm-ID: 238912 [Multi-domain]  Cd Length: 254  Bit Score: 42.39  E-value: 5.32e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 674222734 614 PSSVLPQTVLDKAH--DLVQAGIFKTVLLKVGRHGVVTIDASRAqhHPVPAGKVEVVNTTGCGDSFAGAFAASL 685
Cdd:cd01937  161 LSRVEAEVISTPTElaRLIKETGVKEIIVTDGEEGGYIFDGNGK--YTIPASKKDVVDPTGAGDVFLAAFLYSR 232
RfaE_like cd01172
RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the ...
 622-685 9.92e-04

RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer membrane of gram-negative bacteria. RfaE consists of two domains, a sugar kinase domain, represented here, and a domain belonging to the cytidylyltransferase superfamily.


Pssm-ID: 238577 [Multi-domain]  Cd Length: 304  Bit Score: 41.78  E-value: 9.92e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 674222734 622 VLDKAHDLVQAGIFKTVLLKVGRHGVVTIDASRAQHHpVPAGKVEVVNTTGCGDSFAGAFAASL 685
Cdd:cd01172  206 LEAAGEKLLELLNLEALLVTLGEEGMTLFERDGEVQH-IPALAKEVYDVTGAGDTVIATLALAL 268
bac_FRK cd01167
Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for ...
 654-721 1.06e-03

Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into glucose-6-phosphate. This is in contrast to FRKs [or ketohexokinases (KHKs)] from mammalia and halophilic archaebacteria, which phosphorylate fructose to fructose-1-phosphate.


Pssm-ID: 238572 [Multi-domain]  Cd Length: 295  Bit Score: 41.85  E-value: 1.06e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 674222734 654 RAQHHPVPAGKVEVVNTTGCGDSFAGAFaasLFHLLAQSQGTRavaGRSSPGDQLDLAVRVGQLAARR 721
Cdd:cd01167  230 KGGVGEVPGIPVEVVDTTGAGDAFVAGL---LAQLLSRGLLAL---DEDELAEALRFANAVGALTCTK 291
PTZ00292 PTZ00292
ribokinase; Provisional
 615-685 1.10e-03

ribokinase; Provisional


Pssm-ID: 185541 [Multi-domain]  Cd Length: 326  Bit Score: 42.03  E-value: 1.10e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 674222734 615 SSVLPQTVLDKAHDLVQAGIFKTVLLKVGRHGVVTIDASRAQHHpVPAGKVEVVNTTGCGDSFAGAFAASL 685
Cdd:PTZ00292 215 MEVTDTESAFKASKELQQLGVENVIITLGANGCLIVEKENEPVH-VPGKRVKAVDTTGAGDCFVGSMAYFM 284
PRK09813 PRK09813
fructoselysine 6-kinase; Provisional
 624-723 7.60e-03

fructoselysine 6-kinase; Provisional


Pssm-ID: 182090 [Multi-domain]  Cd Length: 260  Bit Score: 38.95  E-value: 7.60e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674222734 624 DKAHDLVQAGIfKTVLLKVGRHGVVTIDASRAQHHPVPagKVEVVNTTGCGDSFAGAFaasLFHLLAqsqgtravagrss 703
Cdd:PRK09813 175 LKMKAIVARGA-GVVIVTLGENGSIAWDGAQFWRQAPE--PVTVVDTMGAGDSFIAGF---LCGWLA------------- 235

                         90       100
                 ....*....|....*....|
gi 674222734 704 pGDQLDLAVRVGQLAARRTL 723
Cdd:PRK09813 236 -GMTLPQAMAQGTACAAKTI 254
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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