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Conserved domains on  [gi|749460602|dbj|GAM71215|]
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hypothetical protein JCM19236_5863 [Vibrio sp. JCM 19236]

Protein Classification

Big_1 and Big_3_5 domain-containing protein( domain architecture ID 11130888)

Big_1 and Big_3_5 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Big_1 pfam02369
Bacterial Ig-like domain (group 1); This family consists of bacterial domains with an Ig-like ...
 411-476 5.89e-07

Bacterial Ig-like domain (group 1); This family consists of bacterial domains with an Ig-like fold. Members of this family are found in bacterial surface proteins such as intimins and invasins involved in pathogenicity.


:

Pssm-ID: 460541 [Multi-domain]  Cd Length: 64  Bit Score: 47.16  E-value: 5.89e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 749460602  411 ANDVDVAKITVSVR-MNGVAVTGANVFAEVASGDSSigieALNDVTDSEGHAAFEIKSTKAETAQIR 476
Cdd:pfam02369   1 ADGVDTNTVTATVTdANGNPVPGATVTFSASGGTLS----ASSGTTDANGQATVTLTSTKAGTVTVT 63
Invasin_D3 super family cl23771
Invasin, domain 3; Members of this family adopt a structure consisting of an ...
 504-562 1.18e-04

Invasin, domain 3; Members of this family adopt a structure consisting of an immunoglobulin-like beta-sandwich, with seven strands in two beta-sheets, arranged in a Greek-key topology. It forms part of the extracellular region of the protein, which can be expressed as a soluble protein (Inv497) that binds integrins and promotes subsequent uptake by cells when attached to bacteria.


The actual alignment was detected with superfamily member smart00634:

Pssm-ID: 474048 [Multi-domain]  Cd Length: 92  Bit Score: 41.16  E-value: 1.18e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 749460602   504 VIKDNAPSVGGSFDEVRASVQDAYNNTIEGQSVEFDTSNIADTYFENVQVKTDSNGHAT 562
Cdd:smart00634   7 ADKDTAVANGSDAITLTATVTDANGNPVAGQEVTFTTPSGGALTLSKGTATTDANGIAT 65
Cadherin_4 pfam17803
Bacterial cadherin-like domain; This entry contains numerous bacterial cadherin-like domains ...
 160-208 3.20e-04

Bacterial cadherin-like domain; This entry contains numerous bacterial cadherin-like domains found in extracelullar proteins.


:

Pssm-ID: 465514 [Multi-domain]  Cd Length: 71  Bit Score: 39.48  E-value: 3.20e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 749460602  160 VTIAISdGVNSLPVADDFTYSDVVDVSASVTIDVRDYISDPDNDPLQLV 208
Cdd:pfam17803   3 VTITVT-GVNDAPVAVDDTATVDEDTPVTITGNVLANDTDVDGDTLTVT 50
 
Name Accession Description Interval E-value
Big_1 pfam02369
Bacterial Ig-like domain (group 1); This family consists of bacterial domains with an Ig-like ...
 411-476 5.89e-07

Bacterial Ig-like domain (group 1); This family consists of bacterial domains with an Ig-like fold. Members of this family are found in bacterial surface proteins such as intimins and invasins involved in pathogenicity.


Pssm-ID: 460541 [Multi-domain]  Cd Length: 64  Bit Score: 47.16  E-value: 5.89e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 749460602  411 ANDVDVAKITVSVR-MNGVAVTGANVFAEVASGDSSigieALNDVTDSEGHAAFEIKSTKAETAQIR 476
Cdd:pfam02369   1 ADGVDTNTVTATVTdANGNPVPGATVTFSASGGTLS----ASSGTTDANGQATVTLTSTKAGTVTVT 63
BID_1 smart00634
Bacterial Ig-like domain (group 1);
504-562 1.18e-04

Bacterial Ig-like domain (group 1);


Pssm-ID: 214751 [Multi-domain]  Cd Length: 92  Bit Score: 41.16  E-value: 1.18e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 749460602   504 VIKDNAPSVGGSFDEVRASVQDAYNNTIEGQSVEFDTSNIADTYFENVQVKTDSNGHAT 562
Cdd:smart00634   7 ADKDTAVANGSDAITLTATVTDANGNPVAGQEVTFTTPSGGALTLSKGTATTDANGIAT 65
Cadherin_4 pfam17803
Bacterial cadherin-like domain; This entry contains numerous bacterial cadherin-like domains ...
 160-208 3.20e-04

Bacterial cadherin-like domain; This entry contains numerous bacterial cadherin-like domains found in extracelullar proteins.


Pssm-ID: 465514 [Multi-domain]  Cd Length: 71  Bit Score: 39.48  E-value: 3.20e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 749460602  160 VTIAISdGVNSLPVADDFTYSDVVDVSASVTIDVRDYISDPDNDPLQLV 208
Cdd:pfam17803   3 VTITVT-GVNDAPVAVDDTATVDEDTPVTITGNVLANDTDVDGDTLTVT 50
Big_1 pfam02369
Bacterial Ig-like domain (group 1); This family consists of bacterial domains with an Ig-like ...
 513-565 2.12e-03

Bacterial Ig-like domain (group 1); This family consists of bacterial domains with an Ig-like fold. Members of this family are found in bacterial surface proteins such as intimins and invasins involved in pathogenicity.


Pssm-ID: 460541 [Multi-domain]  Cd Length: 64  Bit Score: 36.76  E-value: 2.12e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 749460602  513 GGSFDEVRASVQDAYNNTIEGQSVEFDTSNiADTYfeNVQVKTDSNGHATNKV 565
Cdd:pfam02369   3 GVDTNTVTATVTDANGNPVPGATVTFSASG-GTLS--ASSGTTDANGQATVTL 52
 
Name Accession Description Interval E-value
Big_1 pfam02369
Bacterial Ig-like domain (group 1); This family consists of bacterial domains with an Ig-like ...
 411-476 5.89e-07

Bacterial Ig-like domain (group 1); This family consists of bacterial domains with an Ig-like fold. Members of this family are found in bacterial surface proteins such as intimins and invasins involved in pathogenicity.


Pssm-ID: 460541 [Multi-domain]  Cd Length: 64  Bit Score: 47.16  E-value: 5.89e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 749460602  411 ANDVDVAKITVSVR-MNGVAVTGANVFAEVASGDSSigieALNDVTDSEGHAAFEIKSTKAETAQIR 476
Cdd:pfam02369   1 ADGVDTNTVTATVTdANGNPVPGATVTFSASGGTLS----ASSGTTDANGQATVTLTSTKAGTVTVT 63
BID_1 smart00634
Bacterial Ig-like domain (group 1);
504-562 1.18e-04

Bacterial Ig-like domain (group 1);


Pssm-ID: 214751 [Multi-domain]  Cd Length: 92  Bit Score: 41.16  E-value: 1.18e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 749460602   504 VIKDNAPSVGGSFDEVRASVQDAYNNTIEGQSVEFDTSNIADTYFENVQVKTDSNGHAT 562
Cdd:smart00634   7 ADKDTAVANGSDAITLTATVTDANGNPVAGQEVTFTTPSGGALTLSKGTATTDANGIAT 65
Cadherin_4 pfam17803
Bacterial cadherin-like domain; This entry contains numerous bacterial cadherin-like domains ...
 160-208 3.20e-04

Bacterial cadherin-like domain; This entry contains numerous bacterial cadherin-like domains found in extracelullar proteins.


Pssm-ID: 465514 [Multi-domain]  Cd Length: 71  Bit Score: 39.48  E-value: 3.20e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 749460602  160 VTIAISdGVNSLPVADDFTYSDVVDVSASVTIDVRDYISDPDNDPLQLV 208
Cdd:pfam17803   3 VTITVT-GVNDAPVAVDDTATVDEDTPVTITGNVLANDTDVDGDTLTVT 50
Big_1 pfam02369
Bacterial Ig-like domain (group 1); This family consists of bacterial domains with an Ig-like ...
 513-565 2.12e-03

Bacterial Ig-like domain (group 1); This family consists of bacterial domains with an Ig-like fold. Members of this family are found in bacterial surface proteins such as intimins and invasins involved in pathogenicity.


Pssm-ID: 460541 [Multi-domain]  Cd Length: 64  Bit Score: 36.76  E-value: 2.12e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 749460602  513 GGSFDEVRASVQDAYNNTIEGQSVEFDTSNiADTYfeNVQVKTDSNGHATNKV 565
Cdd:pfam02369   3 GVDTNTVTATVTDANGNPVPGATVTFSASG-GTLS--ASSGTTDANGQATVTL 52
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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