|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05826 |
PRK05826 |
pyruvate kinase; Provisional |
3-468 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 235619 [Multi-domain] Cd Length: 465 Bit Score: 773.17 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 3 RRLRRTKIVCTMGPSTDRDNNLEKIIAAGANVVRMNFSHGTPDDHIGRAERVRSIAKKLGKTVAILGDLQGPKIRVSTFK 82
Cdd:PRK05826 1 RMLRRTKIVATLGPASDSPENLEKLIEAGVNVVRLNFSHGSHEEHGKRAALVREIAAKLGRPVAILLDLKGPKIRVGKFK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 83 DGKIFLNVGDKFILDAElPKGEGTQESVGLDYKTLPQDVVPGDILLLDDGRVQLKVLSTDGAKVFTEVTVGGPLSNNKGI 162
Cdd:PRK05826 81 EGKITLKTGDKFTLDTD-QKEEGDKERVGVDYKGLPKDVKPGDILLLDDGKLQLKVVEVDGDEVETEVKNGGPLSNNKGI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 163 NKLGGGLSADALTEKDKADIITAARIGVDFLAVSFPRSSADLNYARELAQQAG-LNAKIVAKVERAETVANdeaMDDIIL 241
Cdd:PRK05826 160 NIPGGGLSLPALTEKDKADIKFAAEQGVDYIAVSFVRSAEDVEEARRLLREAGcPHAKIIAKIERAEAVDN---IDEIIE 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 242 ASDVIMVARGDLGVEIGDPELVGVQKKLIRRSRQLNRAVITATQMMESMISNPMPTRAEVMDVANAVLDGTDAVMLSAET 321
Cdd:PRK05826 237 ASDGIMVARGDLGVEIPDEEVPGLQKKIIRKAREAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGET 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 322 AAGQYPSETVAAMASVCLGAEKMPSINVSRHRMDKEFETIEESVAMSAMYAANHMKGVAAIVTLSSTGRTPLLMSRISSG 401
Cdd:PRK05826 317 AAGKYPVEAVEAMARICKGAEKEFSINLSKHRLDRQFDRIDEAIAMSAMYAANHLKGVKAIVALTESGRTARLISRFRPG 396
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1393663876 402 LPIFALSRNQETLNLCALYRGVTPIYHGEESRTEAGAKAALQSLKEKGYLSTGDLVLVTQGGQGATQ 468
Cdd:PRK05826 397 APIFAVTRDEKTQRRLALYRGVYPVLFDSAADTDDAAEEALRLLLEKGLVESGDLVVVTSGDPMGTA 463
|
|
| PykF |
COG0469 |
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the ... |
4-477 |
0e+00 |
|
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 440237 [Multi-domain] Cd Length: 471 Bit Score: 713.73 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 4 RLRRTKIVCTMGPSTDRDNNLEKIIAAGANVVRMNFSHGTPDDHIGRAERVRSIAKKLGKTVAILGDLQGPKIRVSTFKD 83
Cdd:COG0469 1 MMRRTKIVATLGPASDSPEVLRKLIEAGMDVARLNFSHGDHEEHRERIELIREAAKELGRPVAILLDLQGPKIRTGKFKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 84 GKIFLNVGDKFILDAElpKGEGTQESVGLDYKTLPQDVVPGDILLLDDGRVQLKVLSTDGAKVFTEVTVGGPLSNNKGIN 163
Cdd:COG0469 81 GPVELKKGDTFTLTTD--DVEGDAERVSVTYPELPEDVKPGDRILLDDGKIELRVEEVEGDEVVCEVVNGGVLSSRKGVN 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 164 KLGGGLSADALTEKDKADIITAARIGVDFLAVSFPRSSADLNYARELAQQAGLNAKIVAKVERAETVANdeaMDDIILAS 243
Cdd:COG0469 159 LPGVGLSLPALTEKDREDLKFALELGVDFIALSFVRSAEDVLEARELLEEAGGRAPIIAKIEKPEAVEN---LDEIIEAS 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 244 DVIMVARGDLGVEIGDPELVGVQKKLIRRSRQLNRAVITATQMMESMISNPMPTRAEVMDVANAVLDGTDAVMLSAETAA 323
Cdd:COG0469 236 DGIMVARGDLGVEIPLEEVPLIQKRIIRKARRAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAV 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 324 GQYPSETVAAMASVCLGAEKMPSINVSRHRM-DKEFETIEESVAMSAMYAANHMkGVAAIVTLSSTGRTPLLMSRISSGL 402
Cdd:COG0469 316 GKYPVEAVETMARIAEEAEKSLDYRRILDRLrDEPERTITDAIARAAVELAEDL-GAKAIVAFTESGSTARRISRYRPKV 394
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1393663876 403 PIFALSRNQETLNLCALYRGVTPIYHGEESRTEAGAKAALQSLKEKGYLSTGDLVLVTQG---GQGATqTNVCRTLIV 477
Cdd:COG0469 395 PILALTPNERTARRLALVWGVYPVLVDDVESTDEMIEEAVEALLEEGLVKPGDLVVITAGvpvGVPGT-TNTLKVHRV 471
|
|
| Pyruvate_Kinase |
cd00288 |
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of ... |
5-477 |
0e+00 |
|
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low affinity T state. PK exists as several different isozymes, depending on organism and tissue type. In mammals, there are four PK isozymes: R, found in red blood cells, L, found in liver, M1, found in skeletal muscle, and M2, found in kidney, adipose tissue, and lung. PK forms a homotetramer, with each subunit containing three domains. The T state to R state transition of PK is more complex than in most allosteric enzymes, involving a concerted rotation of all 3 domains of each monomer in the homotetramer.
Pssm-ID: 238178 [Multi-domain] Cd Length: 480 Bit Score: 699.84 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 5 LRRTKIVCTMGPSTDRDNNLEKIIAAGANVVRMNFSHGTPDDHIGRAERVRSIAKKLGKTVAILGDLQGPKIRVSTFKDG 84
Cdd:cd00288 1 LRRTKIVCTIGPATDSVENLKKLIKAGMNVARMNFSHGSHEYHQSRIDNVREAAEKTGGPVAIALDTKGPEIRTGLFKGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 85 -KIFLNVGDKFILDAELPKGEGTQESVGLDYKTLPQDVVPGDILLLDDGRVQLKVLSTDGA-KVFTEVTVGGPLSNNKGI 162
Cdd:cd00288 81 kDISLKAGDKFLVTTDPAAKKGTKEKIYVDYKNLTKDVSPGNTILVDDGLLSLKVLSKDDDkTLVCEVLNGGVLGSRKGV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 163 NKLGGGLSADALTEKDKADIITAARIGVDFLAVSFPRSSADLNYARELAQQAGLNAKIVAKVERAETVANDeamDDIILA 242
Cdd:cd00288 161 NLPGTDVDLPALSEKDKADLRFGVEQGVDMIFASFVRKASDVLEIREVLGEKGKDIKIIAKIENQEGVNNF---DEILEA 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 243 SDVIMVARGDLGVEIGDPELVGVQKKLIRRSRQLNRAVITATQMMESMISNPMPTRAEVMDVANAVLDGTDAVMLSAETA 322
Cdd:cd00288 238 SDGIMVARGDLGVEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETA 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 323 AGQYPSETVAAMASVCLGAEKMPSINVSRHRMDKEFE---TIEESVAMSAMYAANHMkGVAAIVTLSSTGRTPLLMSRIS 399
Cdd:cd00288 318 KGKYPVEAVKAMARICLEAEKALSHRVLFNEMRRLTPrptSTTEAVAMSAVRAAFEL-GAKAIVVLTTSGRTARLVSKYR 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 400 SGLPIFALSRNQETLNLCALYRGVTPIYHGEE-----SRTEAGAKAALQSLKEKGYLSTGDLVLVTQGGQ-GATQTNVCR 473
Cdd:cd00288 397 PNAPIIAVTRNEQTARQLHLYRGVYPVLFEEPkpgwqEDTDARLKAAVNVAKEKGLLKKGDLVVVVQGWPvGSGSTNTMR 476
|
....
gi 1393663876 474 TLIV 477
Cdd:cd00288 477 ILTV 480
|
|
| pyruv_kin |
TIGR01064 |
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of ... |
6-473 |
0e+00 |
|
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of fructose-1,6-bisphosphate or similar phosphorylated sugars. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273424 [Multi-domain] Cd Length: 472 Bit Score: 652.42 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 6 RRTKIVCTMGPSTDRDNNLEKIIAAGANVVRMNFSHGTPDDHIGRAERVRSIAKKLGKTVAILGDLQGPKIRVSTFKDGK 85
Cdd:TIGR01064 1 RRTKIVCTIGPATNSPEMLKKLLDAGMNVARLNFSHGSHEEHGKRIENVREAAEKLGRPVAILLDTKGPEIRTGEIKGGE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 86 IFLNVGDKFILDAELPKGEGTQESVGLDYKTLPQDVVPGDILLLDDGRVQLKVLSTDGAKVFTEVTVGGPLSNNKGINKL 165
Cdd:TIGR01064 81 VKLKKGDKVIITTDDIKGEGDEEKVYVDYKGLTKDVVEGDKILVDDGKISLVVVSVEGDKVICEVLNGGTLKSKKGVNLP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 166 GGGLSADALTEKDKADIITAARIGVDFLAVSFPRSSADLNYARELAQQAGL-NAKIVAKVERAETVANdeaMDDIILASD 244
Cdd:TIGR01064 161 GADVDLPALSEKDKKDLKFGVEQGVDMVAASFVRTAEDVLEVREVLGEKGAkDVKIIAKIENQEGVDN---IDEIAEASD 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 245 VIMVARGDLGVEIGDPELVGVQKKLIRRSRQLNRAVITATQMMESMISNPMPTRAEVMDVANAVLDGTDAVMLSAETAAG 324
Cdd:TIGR01064 238 GIMVARGDLGVEIPAEEVPIAQKKMIRKCNRAGKPVITATQMLDSMIKNPRPTRAEVSDVANAVLDGTDAVMLSGETAKG 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 325 QYPSETVAAMASVCLGAEKMPS-INVSRHRM--DKEFETIEESVAMSAMYAANHMKgVAAIVTLSSTGRTPLLMSRISSG 401
Cdd:TIGR01064 318 KYPVEAVQMMAKIAKEAEKALAyLTNFNDRKnsDPKPSTITEAIALSAVEAAEKLD-AKAIVVLTESGRTARLLSKYRPN 396
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1393663876 402 LPIFALSRNQETLNLCALYRGVTPIYHGEE-SRTEAGAKAALQSLKEKGYLSTGDLVLVTQGG--QGATQTNVCR 473
Cdd:TIGR01064 397 APIIAVTPNERVARQLALYWGVFPFLVDEEpSDTDARVNKALELLKEKGIVKKGDLVVVIQGGpiGGEGGTNTIR 471
|
|
| PK |
pfam00224 |
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain ... |
5-350 |
0e+00 |
|
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain nested within a larger TIM barrel. The active site is found in a cleft between the two domains.
Pssm-ID: 395168 [Multi-domain] Cd Length: 348 Bit Score: 517.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 5 LRRTKIVCTMGPSTDRDNNLEKIIAAGANVVRMNFSHGTPDDHIGRAERVRSIAKKLGKTVAILGDLQGPKIRVSTFKDG 84
Cdd:pfam00224 1 LRRTKIVCTIGPASNSVENLEKLIEAGANVARMNFSHGSHEYHQSRIDNVREAEEKTGGTVAIALDTKGPEIRTGNTKDG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 85 K--IFLNVGDKFI--LDAELpKGEGTQESVGLDYKTLPQDVVPGDILLLDDGRVQLKVLSTDGAK-VFTEVTVGGPLSNN 159
Cdd:pfam00224 81 KkdIELKAGDEMIvsTDAKY-KGACDDEMIYVDYKNIVKDVSVGGTILVDDGLLSLKVLSKDDDKtLVVEVLNGGVIGSR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 160 KGINKLGGGLSADALTEKDKADIITAARIGVDFLAVSFPRSSADLNYARELAQQAGLNAKIVAKVERAETVANdeaMDDI 239
Cdd:pfam00224 160 KGVNLPGTDVDLPALSEKDKADLRFGVKNGVDMIFASFVRKASDVLEIREVLGEAGKNIQIIAKIENQEGVNN---FDEI 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 240 ILASDVIMVARGDLGVEIGDPELVGVQKKLIRRSRQLNRAVITATQMMESMISNPMPTRAEVMDVANAVLDGTDAVMLSA 319
Cdd:pfam00224 237 LEATDGIMVARGDLGIEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSG 316
|
330 340 350
....*....|....*....|....*....|..
gi 1393663876 320 ETAAGQYPSETVAAMASVCLGAEKM-PSINVS 350
Cdd:pfam00224 317 ETAKGNYPVEAVRMMHEICLEAEKAlPHRNLF 348
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05826 |
PRK05826 |
pyruvate kinase; Provisional |
3-468 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 235619 [Multi-domain] Cd Length: 465 Bit Score: 773.17 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 3 RRLRRTKIVCTMGPSTDRDNNLEKIIAAGANVVRMNFSHGTPDDHIGRAERVRSIAKKLGKTVAILGDLQGPKIRVSTFK 82
Cdd:PRK05826 1 RMLRRTKIVATLGPASDSPENLEKLIEAGVNVVRLNFSHGSHEEHGKRAALVREIAAKLGRPVAILLDLKGPKIRVGKFK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 83 DGKIFLNVGDKFILDAElPKGEGTQESVGLDYKTLPQDVVPGDILLLDDGRVQLKVLSTDGAKVFTEVTVGGPLSNNKGI 162
Cdd:PRK05826 81 EGKITLKTGDKFTLDTD-QKEEGDKERVGVDYKGLPKDVKPGDILLLDDGKLQLKVVEVDGDEVETEVKNGGPLSNNKGI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 163 NKLGGGLSADALTEKDKADIITAARIGVDFLAVSFPRSSADLNYARELAQQAG-LNAKIVAKVERAETVANdeaMDDIIL 241
Cdd:PRK05826 160 NIPGGGLSLPALTEKDKADIKFAAEQGVDYIAVSFVRSAEDVEEARRLLREAGcPHAKIIAKIERAEAVDN---IDEIIE 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 242 ASDVIMVARGDLGVEIGDPELVGVQKKLIRRSRQLNRAVITATQMMESMISNPMPTRAEVMDVANAVLDGTDAVMLSAET 321
Cdd:PRK05826 237 ASDGIMVARGDLGVEIPDEEVPGLQKKIIRKAREAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGET 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 322 AAGQYPSETVAAMASVCLGAEKMPSINVSRHRMDKEFETIEESVAMSAMYAANHMKGVAAIVTLSSTGRTPLLMSRISSG 401
Cdd:PRK05826 317 AAGKYPVEAVEAMARICKGAEKEFSINLSKHRLDRQFDRIDEAIAMSAMYAANHLKGVKAIVALTESGRTARLISRFRPG 396
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1393663876 402 LPIFALSRNQETLNLCALYRGVTPIYHGEESRTEAGAKAALQSLKEKGYLSTGDLVLVTQGGQGATQ 468
Cdd:PRK05826 397 APIFAVTRDEKTQRRLALYRGVYPVLFDSAADTDDAAEEALRLLLEKGLVESGDLVVVTSGDPMGTA 463
|
|
| PykF |
COG0469 |
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the ... |
4-477 |
0e+00 |
|
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 440237 [Multi-domain] Cd Length: 471 Bit Score: 713.73 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 4 RLRRTKIVCTMGPSTDRDNNLEKIIAAGANVVRMNFSHGTPDDHIGRAERVRSIAKKLGKTVAILGDLQGPKIRVSTFKD 83
Cdd:COG0469 1 MMRRTKIVATLGPASDSPEVLRKLIEAGMDVARLNFSHGDHEEHRERIELIREAAKELGRPVAILLDLQGPKIRTGKFKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 84 GKIFLNVGDKFILDAElpKGEGTQESVGLDYKTLPQDVVPGDILLLDDGRVQLKVLSTDGAKVFTEVTVGGPLSNNKGIN 163
Cdd:COG0469 81 GPVELKKGDTFTLTTD--DVEGDAERVSVTYPELPEDVKPGDRILLDDGKIELRVEEVEGDEVVCEVVNGGVLSSRKGVN 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 164 KLGGGLSADALTEKDKADIITAARIGVDFLAVSFPRSSADLNYARELAQQAGLNAKIVAKVERAETVANdeaMDDIILAS 243
Cdd:COG0469 159 LPGVGLSLPALTEKDREDLKFALELGVDFIALSFVRSAEDVLEARELLEEAGGRAPIIAKIEKPEAVEN---LDEIIEAS 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 244 DVIMVARGDLGVEIGDPELVGVQKKLIRRSRQLNRAVITATQMMESMISNPMPTRAEVMDVANAVLDGTDAVMLSAETAA 323
Cdd:COG0469 236 DGIMVARGDLGVEIPLEEVPLIQKRIIRKARRAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAV 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 324 GQYPSETVAAMASVCLGAEKMPSINVSRHRM-DKEFETIEESVAMSAMYAANHMkGVAAIVTLSSTGRTPLLMSRISSGL 402
Cdd:COG0469 316 GKYPVEAVETMARIAEEAEKSLDYRRILDRLrDEPERTITDAIARAAVELAEDL-GAKAIVAFTESGSTARRISRYRPKV 394
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1393663876 403 PIFALSRNQETLNLCALYRGVTPIYHGEESRTEAGAKAALQSLKEKGYLSTGDLVLVTQG---GQGATqTNVCRTLIV 477
Cdd:COG0469 395 PILALTPNERTARRLALVWGVYPVLVDDVESTDEMIEEAVEALLEEGLVKPGDLVVITAGvpvGVPGT-TNTLKVHRV 471
|
|
| Pyruvate_Kinase |
cd00288 |
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of ... |
5-477 |
0e+00 |
|
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low affinity T state. PK exists as several different isozymes, depending on organism and tissue type. In mammals, there are four PK isozymes: R, found in red blood cells, L, found in liver, M1, found in skeletal muscle, and M2, found in kidney, adipose tissue, and lung. PK forms a homotetramer, with each subunit containing three domains. The T state to R state transition of PK is more complex than in most allosteric enzymes, involving a concerted rotation of all 3 domains of each monomer in the homotetramer.
Pssm-ID: 238178 [Multi-domain] Cd Length: 480 Bit Score: 699.84 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 5 LRRTKIVCTMGPSTDRDNNLEKIIAAGANVVRMNFSHGTPDDHIGRAERVRSIAKKLGKTVAILGDLQGPKIRVSTFKDG 84
Cdd:cd00288 1 LRRTKIVCTIGPATDSVENLKKLIKAGMNVARMNFSHGSHEYHQSRIDNVREAAEKTGGPVAIALDTKGPEIRTGLFKGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 85 -KIFLNVGDKFILDAELPKGEGTQESVGLDYKTLPQDVVPGDILLLDDGRVQLKVLSTDGA-KVFTEVTVGGPLSNNKGI 162
Cdd:cd00288 81 kDISLKAGDKFLVTTDPAAKKGTKEKIYVDYKNLTKDVSPGNTILVDDGLLSLKVLSKDDDkTLVCEVLNGGVLGSRKGV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 163 NKLGGGLSADALTEKDKADIITAARIGVDFLAVSFPRSSADLNYARELAQQAGLNAKIVAKVERAETVANDeamDDIILA 242
Cdd:cd00288 161 NLPGTDVDLPALSEKDKADLRFGVEQGVDMIFASFVRKASDVLEIREVLGEKGKDIKIIAKIENQEGVNNF---DEILEA 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 243 SDVIMVARGDLGVEIGDPELVGVQKKLIRRSRQLNRAVITATQMMESMISNPMPTRAEVMDVANAVLDGTDAVMLSAETA 322
Cdd:cd00288 238 SDGIMVARGDLGVEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETA 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 323 AGQYPSETVAAMASVCLGAEKMPSINVSRHRMDKEFE---TIEESVAMSAMYAANHMkGVAAIVTLSSTGRTPLLMSRIS 399
Cdd:cd00288 318 KGKYPVEAVKAMARICLEAEKALSHRVLFNEMRRLTPrptSTTEAVAMSAVRAAFEL-GAKAIVVLTTSGRTARLVSKYR 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 400 SGLPIFALSRNQETLNLCALYRGVTPIYHGEE-----SRTEAGAKAALQSLKEKGYLSTGDLVLVTQGGQ-GATQTNVCR 473
Cdd:cd00288 397 PNAPIIAVTRNEQTARQLHLYRGVYPVLFEEPkpgwqEDTDARLKAAVNVAKEKGLLKKGDLVVVVQGWPvGSGSTNTMR 476
|
....
gi 1393663876 474 TLIV 477
Cdd:cd00288 477 ILTV 480
|
|
| pyruv_kin |
TIGR01064 |
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of ... |
6-473 |
0e+00 |
|
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of fructose-1,6-bisphosphate or similar phosphorylated sugars. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273424 [Multi-domain] Cd Length: 472 Bit Score: 652.42 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 6 RRTKIVCTMGPSTDRDNNLEKIIAAGANVVRMNFSHGTPDDHIGRAERVRSIAKKLGKTVAILGDLQGPKIRVSTFKDGK 85
Cdd:TIGR01064 1 RRTKIVCTIGPATNSPEMLKKLLDAGMNVARLNFSHGSHEEHGKRIENVREAAEKLGRPVAILLDTKGPEIRTGEIKGGE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 86 IFLNVGDKFILDAELPKGEGTQESVGLDYKTLPQDVVPGDILLLDDGRVQLKVLSTDGAKVFTEVTVGGPLSNNKGINKL 165
Cdd:TIGR01064 81 VKLKKGDKVIITTDDIKGEGDEEKVYVDYKGLTKDVVEGDKILVDDGKISLVVVSVEGDKVICEVLNGGTLKSKKGVNLP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 166 GGGLSADALTEKDKADIITAARIGVDFLAVSFPRSSADLNYARELAQQAGL-NAKIVAKVERAETVANdeaMDDIILASD 244
Cdd:TIGR01064 161 GADVDLPALSEKDKKDLKFGVEQGVDMVAASFVRTAEDVLEVREVLGEKGAkDVKIIAKIENQEGVDN---IDEIAEASD 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 245 VIMVARGDLGVEIGDPELVGVQKKLIRRSRQLNRAVITATQMMESMISNPMPTRAEVMDVANAVLDGTDAVMLSAETAAG 324
Cdd:TIGR01064 238 GIMVARGDLGVEIPAEEVPIAQKKMIRKCNRAGKPVITATQMLDSMIKNPRPTRAEVSDVANAVLDGTDAVMLSGETAKG 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 325 QYPSETVAAMASVCLGAEKMPS-INVSRHRM--DKEFETIEESVAMSAMYAANHMKgVAAIVTLSSTGRTPLLMSRISSG 401
Cdd:TIGR01064 318 KYPVEAVQMMAKIAKEAEKALAyLTNFNDRKnsDPKPSTITEAIALSAVEAAEKLD-AKAIVVLTESGRTARLLSKYRPN 396
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1393663876 402 LPIFALSRNQETLNLCALYRGVTPIYHGEE-SRTEAGAKAALQSLKEKGYLSTGDLVLVTQGG--QGATQTNVCR 473
Cdd:TIGR01064 397 APIIAVTPNERVARQLALYWGVFPFLVDEEpSDTDARVNKALELLKEKGIVKKGDLVVVIQGGpiGGEGGTNTIR 471
|
|
| PK |
pfam00224 |
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain ... |
5-350 |
0e+00 |
|
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain nested within a larger TIM barrel. The active site is found in a cleft between the two domains.
Pssm-ID: 395168 [Multi-domain] Cd Length: 348 Bit Score: 517.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 5 LRRTKIVCTMGPSTDRDNNLEKIIAAGANVVRMNFSHGTPDDHIGRAERVRSIAKKLGKTVAILGDLQGPKIRVSTFKDG 84
Cdd:pfam00224 1 LRRTKIVCTIGPASNSVENLEKLIEAGANVARMNFSHGSHEYHQSRIDNVREAEEKTGGTVAIALDTKGPEIRTGNTKDG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 85 K--IFLNVGDKFI--LDAELpKGEGTQESVGLDYKTLPQDVVPGDILLLDDGRVQLKVLSTDGAK-VFTEVTVGGPLSNN 159
Cdd:pfam00224 81 KkdIELKAGDEMIvsTDAKY-KGACDDEMIYVDYKNIVKDVSVGGTILVDDGLLSLKVLSKDDDKtLVVEVLNGGVIGSR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 160 KGINKLGGGLSADALTEKDKADIITAARIGVDFLAVSFPRSSADLNYARELAQQAGLNAKIVAKVERAETVANdeaMDDI 239
Cdd:pfam00224 160 KGVNLPGTDVDLPALSEKDKADLRFGVKNGVDMIFASFVRKASDVLEIREVLGEAGKNIQIIAKIENQEGVNN---FDEI 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 240 ILASDVIMVARGDLGVEIGDPELVGVQKKLIRRSRQLNRAVITATQMMESMISNPMPTRAEVMDVANAVLDGTDAVMLSA 319
Cdd:pfam00224 237 LEATDGIMVARGDLGIEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSG 316
|
330 340 350
....*....|....*....|....*....|..
gi 1393663876 320 ETAAGQYPSETVAAMASVCLGAEKM-PSINVS 350
Cdd:pfam00224 317 ETAKGNYPVEAVRMMHEICLEAEKAlPHRNLF 348
|
|
| PRK06247 |
PRK06247 |
pyruvate kinase; Provisional |
3-462 |
2.73e-146 |
|
pyruvate kinase; Provisional
Pssm-ID: 180487 [Multi-domain] Cd Length: 476 Bit Score: 426.65 E-value: 2.73e-146
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 3 RRLRRTKIVCTMGPSTDRDNNLEKIIAAGANVVRMNFSHGTPDDHIGRAERVRSIAKKLGKTVAILGDLQGPKIRVSTFK 82
Cdd:PRK06247 2 KRNRRVKILATLGPASSSEDMIRKLVEAGADVFRLNFSHGDHDDHRELYKRIREVEDETGRPIGILADLQGPKLRLGRFA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 83 DGKIFLNVGDKFILDAElpKGEGTQESVGLDYKTLPQDVVPGDILLLDDGRVQLKVLSTDGAKVFTEVTVGGPLSNNKGI 162
Cdd:PRK06247 82 DGKVQLANGQTFRLDVD--DAPGDHDRVSLPHPEIAAALKPGDRLLVDDGKVRLVVEACDGDDVVCRVVEGGPVSDRKGV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 163 NKLGGGLSADALTEKDKADIITAARIGVDFLAVSFPRSSADLNYARELAqqaGLNAKIVAKVERAETVandEAMDDIILA 242
Cdd:PRK06247 160 SLPGTVLSVSALTEKDRADLEFALELGVDWVALSFVQRPEDVEEVRKII---GGRVPVMAKIEKPQAI---DRLEAIVEA 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 243 SDVIMVARGDLGVEIGDPELVGVQKKLIRRSRQLNRAVITATQMMESMISNPMPTRAEVMDVANAVLDGTDAVMLSAETA 322
Cdd:PRK06247 234 SDAIMVARGDLGVEVPLEQVPLIQKRIIRAARRAGKPVVVATQMLESMIENPVPTRAEVSDVATAVLDGADAVMLSAETA 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 323 AGQYPSETVAAMASVCLGAEKMPS----INVSRhrmdkefeTIEESVAMSAM-YAANHMKG---VAAIVTLSSTGRTPLL 394
Cdd:PRK06247 314 SGKYPVEAVRTMARIIRQVERDPTypplIHAQR--------PQPEATKRDAIsYAARDIAErldLAALVAYTSSGDTALR 385
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1393663876 395 MSRISSGLPIFALSRNQETLNLCALYRGVTPIYHGEESRTEAGAKAALQSLKEKGYLSTGDLVLVTQG 462
Cdd:PRK06247 386 AARERPPLPILALTPNPETARRLALTWGVHCVVVDDARDTDDMVRRADRIALAEGFYKRGDRVVIVAG 453
|
|
| PRK06354 |
PRK06354 |
pyruvate kinase; Provisional |
1-462 |
9.70e-144 |
|
pyruvate kinase; Provisional
Pssm-ID: 235784 [Multi-domain] Cd Length: 590 Bit Score: 424.34 E-value: 9.70e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 1 MSRR--LRRTKIVCTMGPSTDRDNNLEKIIAAGANVVRMNFSHGTPDDHIGRAERVRSIAKKLGKTVAILGDLQGPKIRV 78
Cdd:PRK06354 1 MSLRdlMRRTKIVATIGPASESPEKLRQLIEAGATTARLNFSHGDHEEHGARIKNIREASKKLGKTVGILQDLQGPKIRL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 79 STFKDGKIFLNVGDKFILDAElpKGEGTQESVGLDYKTLPQDVVPGDILLLDDGRVQLKVLSTDGAK--VFTEVTVGGPL 156
Cdd:PRK06354 81 GRFEDGPIELKTGDEFILTSR--EVLGTQEKFSVTYDGLADEVPVGSRILLDDGLIELEVEEVDKADgeLHCKVLVGGVL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 157 SNNKGINKLGGGLSADALTEKDKADIITAARIGVDFLAVSFPRSSADLNYAREL-AQQAGLNAKIVAKVERAETVANdea 235
Cdd:PRK06354 159 SNKKGVNFPGVSLSLPAITEKDREDLIFGLEQGVDWIALSFVRNPSDVLEIRELiEEHNGKHIPIIAKIEKQEAIDN--- 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 236 MDDIILASDVIMVARGDLGVEIGDPELVGVQKKLIRRSRQLNRAVITATQMMESMISNPMPTRAEVMDVANAVLDGTDAV 315
Cdd:PRK06354 236 IDAILELCDGLMVARGDLGVEIPAEEVPLLQKRLIKKANRLGKPVITATQMLDSMQRNPRPTRAEASDVANAILDGTDAV 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 316 MLSAETAAGQYPSETVAAMASVCLGAEK-MPSINVSRHRmDKEFETIEESVAMSAMYAANHMkGVAAIVTLSSTGRTPLL 394
Cdd:PRK06354 316 MLSNETAAGDYPVEAVQTMATIAVRIEKdLPYRDILSKR-PEFTTTITNAISQAVSHIALQL-DAAAIVTLTKSGATARN 393
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1393663876 395 MSRISSGLPIFALSRNQETLNLCALYRGVTPIYHGEESRTEAGAKAALQSLKEKGYLSTGDLVLVTQG 462
Cdd:PRK06354 394 VSKYRPKTPILAVTPNESVARRLQLVWGVTPLLVLDAPSTDETFDAAINVAQESGLLKQGDLVVITAG 461
|
|
| PRK09206 |
PRK09206 |
pyruvate kinase PykF; |
5-469 |
3.62e-118 |
|
pyruvate kinase PykF;
Pssm-ID: 181699 [Multi-domain] Cd Length: 470 Bit Score: 354.75 E-value: 3.62e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 5 LRRTKIVCTMGPSTDRDNNLEKIIAAGANVVRMNFSHGTPDDHIGRAERVRSIAKKLGKTVAILGDLQGPKIRVSTFKDG 84
Cdd:PRK09206 1 MKKTKIVCTIGPKTESEEMLTKLLDAGMNVMRLNFSHGDYAEHGQRIKNLRNVMSKTGKKAAILLDTKGPEIRTMKLEGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 85 K-IFLNVGDKFIL--DAELpkgEGTQESVGLDYKTLPQDVVPGDILLLDDGRVQLKVLSTDGAKVFTEVTVGGPLSNNKG 161
Cdd:PRK09206 81 NdVSLKAGQTFTFttDKSV---VGNKERVAVTYEGFTADLSVGNTVLVDDGLIGMEVTAITGNEVICKVLNNGDLGENKG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 162 INKLGGGLSADALTEKDKADIITAARIGVDFLAVSFPRSSADLNYARE-LAQQAGLNAKIVAKVERAETVANdeaMDDII 240
Cdd:PRK09206 158 VNLPGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVLEIREhLKAHGGENIQIISKIENQEGLNN---FDEIL 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 241 LASDVIMVARGDLGVEIGDPELVGVQKKLIRRSRQLNRAVITATQMMESMISNPMPTRAEVMDVANAVLDGTDAVMLSAE 320
Cdd:PRK09206 235 EASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCNRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGE 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 321 TAAGQYPSETVAAMASVCLGAEK-MPSINVSRHRMDKefETIEESVAMSAMYAANHMkGVAAIVTLSSTGRTPLLMSRIS 399
Cdd:PRK09206 315 SAKGKYPLEAVSIMATICERTDRvMNSRLESNNDNRK--LRITEAVCRGAVETAEKL-DAPLIVVATQGGKSARSVRKYF 391
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1393663876 400 SGLPIFALSRNQETLNLCALYRGVTPIYHGEESRTEA----GAKAALQSlkekGYLSTGDLVLVTQGG---QGATQT 469
Cdd:PRK09206 392 PDATILALTTNEKTARQLVLSKGVVPQLVKEIASTDDfyrlGKELALQS----GLAQKGDVVVMVSGAlvpSGTTNT 464
|
|
| PTZ00066 |
PTZ00066 |
pyruvate kinase; Provisional |
4-478 |
7.84e-104 |
|
pyruvate kinase; Provisional
Pssm-ID: 173361 [Multi-domain] Cd Length: 513 Bit Score: 319.40 E-value: 7.84e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 4 RLRRTKIVCTMGPSTDRDNNLEKIIAAGANVVRMNFSHGTPDDHIGRAERVRSIAKKL-GKTVAILGDLQGPKIRVSTFK 82
Cdd:PTZ00066 36 RQKKTHIVCTMGPACKNVETLVKLIDAGMNICRFNFSHGDHESHKKTLNNVREAAKARpNANLGILLDTKGPEIRTGFLK 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 83 DGK-IFLNVGD--KFILDAELpkgEGTQESVGLDYKTLPQDVVPGDILLLDDGRVQLKVLSTDGAKVFTEVTVGGPLSNN 159
Cdd:PTZ00066 116 NHKpITLKEGQtlKITTDYTF---LGDETCISCSYKKLPQSVKVGNIILIADGSLSCKVLEVHDDYIITKVLNNATIGER 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 160 KGINKLGGGLSADALTEKDKADIIT-AARIGVDFLAVSFPRSSADLNYARELAQQAGLNAKIVAKVERAETVANdeaMDD 238
Cdd:PTZ00066 193 KNMNLPGVKVELPVIGEKDKNDILNfAIPMGCDFIALSFVQSADDVRLCRQLLGERGRHIKIIPKIENIEGLIN---FDE 269
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 239 IILASDVIMVARGDLGVEIgDPELVGV-QKKLIRRSRQLNRAVITATQMMESMISNPMPTRAEVMDVANAVLDGTDAVML 317
Cdd:PTZ00066 270 ILAESDGIMVARGDLGMEI-PPEKVFLaQKMMISKCNVAGKPVITATQMLESMIKNPRPTRAESTDVANAVLDGTDCVML 348
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 318 SAETAAGQYPSETVAAMASVCLGAEKMPSINVSRHRMDKEFET---IEESVAMSAMYAAnHMKGVAAIVTLSSTGRTPLL 394
Cdd:PTZ00066 349 SGETANGKFPVEAVNIMAKICFEAETCIDYRVLYHAIHLAVPTpvsVQEAVARSAVETA-EDINAKLIIALTETGNTARL 427
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 395 MSRISSGLPIFALSRNQETLNLCALYRGVTPIYHGEESRTEAGAKAALQSLKEKGYLSTGDLVLVTQGGQG--ATQTNVC 472
Cdd:PTZ00066 428 ISKYRPSCTILALSASPSVVKSLSVARGVTTYVVNSFQGTDVVIRNAIALAKERGLVESGDSAIAVHGVKEevAGSSNLM 507
|
....*.
gi 1393663876 473 RTLIVE 478
Cdd:PTZ00066 508 KVVKIP 513
|
|
| PLN02461 |
PLN02461 |
Probable pyruvate kinase |
2-457 |
2.84e-99 |
|
Probable pyruvate kinase
Pssm-ID: 215255 [Multi-domain] Cd Length: 511 Bit Score: 307.29 E-value: 2.84e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 2 SRRLRRTKIVCTMGPSTDRDNNLEKIIAAGANVVRMNFSHGTPDDHIGRAERVRSIAKKLGKTVAILGDLQGPKIRVSTF 81
Cdd:PLN02461 17 GLRRPKTKIVCTLGPASRSVPMLEKLLRAGMNVARFNFSHGSHEYHQETLDNLRQAMANTGILCAVMLDTKGPEIRTGFL 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 82 KDGK-IFLNVGDKFIL--DAELpkgEGTQESVGLDYKTLPQDVVPGDILLLDDGRVQLKVLSTDGAK--VFTEVTVGGPL 156
Cdd:PLN02461 97 KDGKpVQLKQGQEITIttDYSI---KGDENMIAMSYKKLAVDVKPGSVILCADGTITLTVLSCDVEAgtVRCRCENSAML 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 157 SNNKGINKLGGGLSADALTEKDKADIIT-AARIGVDFLAVSFPRSSADLNYARELAQQAGLNAKIVAKVERAETVANdea 235
Cdd:PLN02461 174 GERKNVNLPGVVVDLPTLTEKDKEDILQwGVPNKIDFIALSFVRKGSDLVEVRKVLGEHAKSILLISKVENQEGLDN--- 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 236 MDDIILASDVIMVARGDLGVEIGDPELVGVQKKLIRRSRQLNRAVITATQMMESMISNPMPTRAEVMDVANAVLDGTDAV 315
Cdd:PLN02461 251 FDDILAESDAFMVARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCV 330
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 316 MLSAETAAGQYPSETVAAMASVCLGAEKmpSIN---VSRHRMDKE---FETIeESVAMSAMYAANHMKGvAAIVTLSSTG 389
Cdd:PLN02461 331 MLSGETAAGAYPELAVKTMARICREAEA--SLDygaLFKEIMRSAplpMSPL-ESLASSAVRTANKVKA-SLIVVLTRGG 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 390 RTPLLMSRISSGLPI------------FALSRNQET-LNLCALYRGVTPIYHGEESR------TEAGAKAALQSLKEKGY 450
Cdd:PLN02461 407 TTARLVAKYRPAVPIlsvvvpeittdsFDWSCSDEApARHSLIYRGLIPVLAEGSAKatdsesTEEILEAAIEHAKKKGL 486
|
....*..
gi 1393663876 451 LSTGDLV 457
Cdd:PLN02461 487 CKPGDSV 493
|
|
| PTZ00300 |
PTZ00300 |
pyruvate kinase; Provisional |
33-478 |
5.88e-87 |
|
pyruvate kinase; Provisional
Pssm-ID: 140321 [Multi-domain] Cd Length: 454 Bit Score: 273.85 E-value: 5.88e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 33 NVVRMNFSHGTPDDHIGRAERVRSIAKKLGKTVAILGDLQGPKIRVSTFKDGKIFLNVGDKFILDAELP-KGEGTQESVG 111
Cdd:PTZ00300 2 SVARMNFSHGSHEYHQTTINNVRQAAAELGVNIAIALDTKGPEIRTGLFVGGEAVMERGATCYVTTDPAfADKGTKDKFY 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 112 LDYKTLPQDVVPGDILLLDDGRVQLKVLSTDGAKVFT-EVTVGGPLSNNKGINKLGGGLSADALTEKDKADIITAARIGV 190
Cdd:PTZ00300 82 IDYQNLSKVVRPGGYIYIDDGILILHVQSHEDEQTLKcTVTNAHTISDRRGVNLPGCDVDLPAVSAKDCADLQFGVEQGV 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 191 DFLAVSFPRSSADLNYARELAQQAGLNAKIVAKVERAETVANdeaMDDIILASDVIMVARGDLGVEIGDPELVGVQKKLI 270
Cdd:PTZ00300 162 DMIFASFIRSAEQVGEVRKALGAKGGDIMIICKIENHQGVQN---IDSIIEESDGIMVARGDLGVEIPAEKVVVAQKILI 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 271 RRSRQLNRAVITATQMMESMISNPMPTRAEVMDVANAVLDGTDAVMLSAETAAGQYPSETVAAMASVCLGAEKMPSINV- 349
Cdd:PTZ00300 239 SKCNVAGKPVICATQMLESMTYNPRPTRAEVSDVANAVFNGADCVMLSGETAKGKYPNEVVQYMARICLEAQSAVNEYVf 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 350 --SRHRMDKEFETIEESVAMSAMYAANHMKGvAAIVTLSSTGRTPLLMSRISSGLPIFALSRNQETLNLCALYRGVTPIY 427
Cdd:PTZ00300 319 fnSIKKLQPIPMSAEEAVCSSAVNSVYETKA-KALVVLSNTGRSARLVAKYRPNCPIVCVTTRLQTCRQLNITQGVESVF 397
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1393663876 428 ---------HGEESRTEAGAKAAlqslKEKGYLSTGDLVLVTQGGQGAT-QTNVCRTLIVE 478
Cdd:PTZ00300 398 fdaerlghdEGKEQRVAMGVGFA----KSKGYVQSGDLMVVVHADHKVKgYANQTRIILVS 454
|
|
| PRK06739 |
PRK06739 |
pyruvate kinase; Validated |
11-342 |
5.02e-86 |
|
pyruvate kinase; Validated
Pssm-ID: 180676 [Multi-domain] Cd Length: 352 Bit Score: 267.97 E-value: 5.02e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 11 VCTMGPSTDRDNNLEKIIAAGANVVRMNFSHGTPDDHIGRAERVRSiakkLGKTVAILGDLQGPKIRVSTFKDGKIFLNV 90
Cdd:PRK06739 6 ICTIGPASNNKETLAQLINNGMKIVRLNLSHGTHESHKDIIRLVKS----LDDSIKILGDVQGPKIRLGEIKGEQITLQA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 91 GDKFILDAELPKGEGTQESVglDYKTLPQDVVPGDILLLDDGRVQLKVLSTDGAKVFTEVTVGGPLSNNKGINKLGGGLS 170
Cdd:PRK06739 82 GDSFILHTQPVTGSSTEASV--DYEGIANDVKVGSRILMNDGEVELIVEKVSTDKIETKVKTGGNISSHKGVNLPGAIVR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 171 ADALTEKDKADIITAARIGVDFLAVSFPRSSADLNYARELAQQAGLNA-KIVAKVERAETVANdeaMDDIILASDVIMVA 249
Cdd:PRK06739 160 LPAITEKDKKDIQFLLEEDVDFIACSFVRKPSHIKEIRDFIQQYKETSpNLIAKIETMEAIEN---FQDICKEADGIMIA 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 250 RGDLGVEIGDPELVGVQKKLIRRSRQLNRAVITATQMMESMISNPMPTRAEVMDVANAVLDGTDAVMLSAETAAGQYPSE 329
Cdd:PRK06739 237 RGDLGVELPYQFIPLLQKMMIQECNRTNTYVITATQMLQSMVDHSIPTRAEVTDVFQAVLDGTNAVMLSAESASGEHPIE 316
|
330
....*....|...
gi 1393663876 330 TVAAMASVCLGAE 342
Cdd:PRK06739 317 SVSTLRLVSEFAE 329
|
|
| PLN02623 |
PLN02623 |
pyruvate kinase |
6-463 |
1.16e-84 |
|
pyruvate kinase
Pssm-ID: 215334 [Multi-domain] Cd Length: 581 Bit Score: 271.80 E-value: 1.16e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 6 RRTKIVCTMGPSTDRDNNLEKIIAAGANVVRMNFSHGTPDDHIGRAERVRSI-AKKLGKTVAILGDLQGPKIRVSTFKDg 84
Cdd:PLN02623 110 RKTKIVCTIGPSTNTREMIWKLAEAGMNVARLNMSHGDHASHQKVIDLVKEYnAQSKDNVIAIMLDTKGPEVRSGDLPQ- 188
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 85 KIFLNVGDKFILdaELPKGEGTQESVGLDYKTLPQDVVPGDILLLDDGRVQLKVLSTDGAKVFTEVTVGGPLSNNKGINK 164
Cdd:PLN02623 189 PIMLEEGQEFTF--TIKRGVSTEDCVSVNYDDFVNDVEVGDMLLVDGGMMSLAVKSKTSDSVKCEVVDGGELKSRRHLNV 266
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 165 LGGGLSADALTEKDKADIITAARIGVDFLAVSFPRSSADLNYARELAQQAGLNAKIVAKVERAETVANdeaMDDIILASD 244
Cdd:PLN02623 267 RGKSATLPSITEKDWEDIKFGVENKVDFYAVSFVKDAQVVHELKDYLKSCNADIHVIVKIESADSIPN---LHSIITASD 343
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 245 VIMVARGDLGVEIGDPELVGVQKKLIRRSRQLNRAVITATQMMESMISNPMPTRAEVMDVANAVLDGTDAVMLSAETAAG 324
Cdd:PLN02623 344 GAMVARGDLGAELPIEEVPLLQEEIIRRCRSMGKPVIVATNMLESMIVHPTPTRAEVSDIAIAVREGADAVMLSGETAHG 423
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 325 QYPSETVAAMASVCLGAEKMPSINVSRHRMDKEFETieesvAMSAMYA--ANHMKGV--AAIVTLSSTGRTPLLMSRISS 400
Cdd:PLN02623 424 KFPLKAVKVMHTVALRTEATLPEGTTPPNLGQAFKN-----HMSEMFAfhATMMANTlgTSIIVFTRTGFMAILLSHYRP 498
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1393663876 401 GLPIFALSRNQETLNLCALYRGVTPIYHGEESRTEAGAKAALQSLKEKGYLSTGDLVLVTQGG 463
Cdd:PLN02623 499 SGTIFAFTNEKRIQQRLALYQGVCPIYMQFSDDAEETFARALSLLLNKGMVKEGEEVALVQSG 561
|
|
| PLN02762 |
PLN02762 |
pyruvate kinase complex alpha subunit |
3-459 |
2.59e-78 |
|
pyruvate kinase complex alpha subunit
Pssm-ID: 215407 [Multi-domain] Cd Length: 509 Bit Score: 253.13 E-value: 2.59e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 3 RRLRRTKIVCTMGPSTDRDNNLEKIIAAGANVVRMNFSHGTPDDHIGRAERVRSIAKKLGKTVAILGDLQGPKIRVSTF- 81
Cdd:PLN02762 22 RSTRRTKLVCTIGPACCGFEQLEALAMGGMNVARLNMCHGTREWHRDVIRRVRRLNEEKGFAVAVMMDTEGSEIHMGDLg 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 82 -------KDGKIFLNVGDKFildaELPKGEGTqesVGLDYKTLPQDVVPGDILLLDDGRVQLKVLSTDGAKVFTEVTVGG 154
Cdd:PLN02762 102 gassakaEDGEEWTFTVRKF----DGSRPEFT---IQVNYDGFAEDVKVGDELVVDGGMVRFEVIEKIGPDVKCKCTDPG 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 155 PL---------SNNKGINKLGGGLSAdaLTEKDKADIITAARIGVDFLAVSFPRSSADLNYARELAQQAGLNAKI--VAK 223
Cdd:PLN02762 175 LLlpranltfwRDGSLVRERNAMLPT--ISSKDWLDIDFGISEGVDFIAVSFVKSAEVIKHLKSYIAARSRDSDIgvIAK 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 224 VERAETVANdeaMDDIILASDVIMVARGDLGVEIGDPELVGVQKKLIRRSRQLNRAVITATQMMESMISNPMPTRAEVMD 303
Cdd:PLN02762 253 IESLDSLKN---LEEIIRASDGAMVARGDLGAQIPLEQVPSVQEKIVRLCRQLNKPVIVASQLLESMIEYPTPTRAEVAD 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 304 VANAVLDGTDAVMLSAETAAGQYPSETVAAMASVCLGAEKMpSINVSRHRMDKEFE-------TIEESVAMSAMYAANHM 376
Cdd:PLN02762 330 VSEAVRQRADALMLSGESAMGLYPEKALSVLRSVSLRMELW-SREEKRHEALELPQlssslsdRISEEICNSAAKMANNL 408
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 377 kGVAAIVTLSSTGRTPLLMSRISSGLPIFALSRNQETLNLCALYRGVTPIYHGEESRTEAGAKAALQSLKEKGYLSTGDL 456
Cdd:PLN02762 409 -GVDAIFVYTKHGHMASLLSRNRPDCPIFAFTDTTSVRRRLNLQWGLIPFRLDFSDDMESNLNKTFSLLKARGMIKSGDL 487
|
...
gi 1393663876 457 VLV 459
Cdd:PLN02762 488 VIA 490
|
|
| PLN02765 |
PLN02765 |
pyruvate kinase |
8-461 |
6.19e-69 |
|
pyruvate kinase
Pssm-ID: 215409 [Multi-domain] Cd Length: 526 Bit Score: 228.79 E-value: 6.19e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 8 TKIVCTMGPSTDRDNNLEKIIAAGANVVRMNFSHGTPDDHIGRAERVRSIAKKLGKTVAILGDLQGPKIRVSTFKDGKIF 87
Cdd:PLN02765 30 TKIVGTLGPKSRSVEVIEACLKAGMSVARFDFSWGDAEYHQETLENLKIAVKNTKKLCAVMLDTVGPELQVINKTEKPIS 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 88 LNVGDKFILDAELPKgEGTQESVGLDYKTLPQDVVPGDILLL--------DDGRVQLKVLSTDGAKVFTEV----TVGGP 155
Cdd:PLN02765 110 LKAGNTVTLTPDQSK-EASSEVLPINFPGLAKAVKPGDTIFVgqylftgsETTSVWLEVDEVKGDDVVCTVknsaTLAGS 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 156 L----SNNKGInklggglSADALTEKDKADIIT-AARIGVDFLAVSFPRSSADLNYARELAQQAGLN-AKIVAKVERAET 229
Cdd:PLN02765 189 LftlhVSQVRI-------DLPTLSEKDKEVISTwGVPNKIDFLSLSYTRHAEDVREAREFLSSLGLSqTQIFAKIENVEG 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 230 VANdeaMDDIILASDVIMVARGDLGVEIgDPELVGV-QKKLIRRSRQLNRAVITaTQMMESMISNPMPTRAEVMDVANAV 308
Cdd:PLN02765 262 LTH---FDEILQEADGIILSRGNLGIDL-PPEKVFLfQKAALYKCNMAGKPAVV-TRVVDSMTDNLRPTRAEATDVANAV 336
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 309 LDGTDAVMLSAETAAGQYPSETVAAMASVCLGAEKMPSINVSRHRMDK---EFETIEESVAMSAMYAANHMKGvAAIVTL 385
Cdd:PLN02765 337 LDGADAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLYFKKTVKyvgEPMSHLESIASSAVRAAIKVKA-SVIIVF 415
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 386 SSTGRTPLLMSRISSGLPIFALSRNQETLNL-------------CALYRGVTPIY----HGEES---RTEAGAKAALQSL 445
Cdd:PLN02765 416 TSSGRAARLIAKYRPTMPVLSVVIPRLKTNQlkwsftgafqarqCLIVRGLFPMLadprHSAEStsaTNESVLKVALDHG 495
|
490
....*....|....*.
gi 1393663876 446 KEKGYLSTGDLVLVTQ 461
Cdd:PLN02765 496 KAAGVIKSHDRVVVCQ 511
|
|
| PRK08187 |
PRK08187 |
pyruvate kinase; Validated |
3-337 |
6.27e-38 |
|
pyruvate kinase; Validated
Pssm-ID: 236178 Cd Length: 493 Bit Score: 144.77 E-value: 6.27e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 3 RRLRRTKIVCTMgPSTDRDNN--LEKIIAAGANVVRMNFSHGTPDDHIGRAERVRSIAKKLGKTVAILGDLQGPKIRVST 80
Cdd:PRK08187 130 PAARRTRIMVTL-PSEAADDPdfVLRLAERGMDCARINCAHDDPAAWQAMIGHLRQAERATGRRCKILMDLAGPKIRTGA 208
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 81 F--KDGKIFLNVGDKFILDAELPKgEGTQESVGLDYKTLPQ---DVVPGDILLLDDGRVQLKVLSTDGAKVFTEVTVGGP 155
Cdd:PRK08187 209 VagPLGKTRLYTGDRLALVAQGPP-RRIDEEHFQVTCTLPEilaRLAVGARVWIDDGKLGARVERVGPGGALLEVTHARP 287
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 156 ----LSNNKGINKLGGGLSADALTEKDKADIITAARiGVDFLAVSFPRSSADLN-YARELAQQAGLNAK---IVAKVERA 227
Cdd:PRK08187 288 kglkLKPEKGLNFPDTALDLPALTEKDRADLDFVAR-HADLVGYSFVQSPGDVEaLQAALAARRPDDWRklgLVLKIETP 366
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 228 ETVANdeaMDDIILASD-----VIMVARGDLGVEIGDPELVGVQKKLIRRSRQLNRAVITATQMMESMISNPMPTRAEVM 302
Cdd:PRK08187 367 RAVAN---LPELIVQAAgrqpfGVMIARGDLAVEIGFERLAEMQEEILWLCEAAHVPVIWATQVLEGLVKKGLPSRAEMT 443
|
330 340 350
....*....|....*....|....*....|....*
gi 1393663876 303 DVANAvlDGTDAVMLSaetaAGQYPSETVAAMASV 337
Cdd:PRK08187 444 DAAMA--ARAECVMLN----KGPYLVEAVTFLDDL 472
|
|
| PK_C |
pfam02887 |
Pyruvate kinase, alpha/beta domain; As well as being found in pyruvate kinase this family is ... |
363-473 |
1.30e-31 |
|
Pyruvate kinase, alpha/beta domain; As well as being found in pyruvate kinase this family is found as an isolated domain in some bacterial proteins.
Pssm-ID: 460738 [Multi-domain] Cd Length: 114 Bit Score: 117.20 E-value: 1.30e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 363 ESVAMSAMYAANHMkGVAAIVTLSSTGRTPLLMSRISSGLPIFALSRNQETLNLCALYRGVTPIYHGEESRTEAGAKAAL 442
Cdd:pfam02887 1 EAIAHAAVEAAEEL-GAKAIVVLTESGYTARLISRYRPGVPIIAVTPNELTARQLALYWGVYPVLFDEAETTDEMLRRAV 79
|
90 100 110
....*....|....*....|....*....|....
gi 1393663876 443 QSLKEKGYLSTGDLVLVTQG---GQGATqTNVCR 473
Cdd:pfam02887 80 KVAKEAGLVKKGDLVVITAGvpfGVSGT-TNTLK 112
|
|
| PRK14725 |
PRK14725 |
pyruvate kinase; Provisional |
81-317 |
1.82e-26 |
|
pyruvate kinase; Provisional
Pssm-ID: 237804 Cd Length: 608 Bit Score: 112.74 E-value: 1.82e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 81 FKDGKIFLNVGDKFILDAEL-----PKGEGTQESVGLdykTLPQ---DVVPGDILLLDDGRVQLKVLSTDGAKVFTEVTV 152
Cdd:PRK14725 328 PVEQKLRLKVGDRLVLTRDDapgdpAQGDAPPARISC---TLPEafrAARVGERVWFDDGKIGAVVVKVEADEVELRITH 404
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 153 GGP----LSNNKGINKLGGGLSADALTEKDKADIITAARIGvDFLAVSFPRSSADLNYA-RELAQQAGLNAKIVAKVEra 227
Cdd:PRK14725 405 ARPggskLKAGKGINLPDSHLPLPALTDKDLEDLAFVAKHA-DIVALSFVRSPEDVRLLlDALEKLGADDLGVVLKIE-- 481
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393663876 228 eTVANDEAMDDIILAS----DV-IMVARGDLGVEIGDPELVGVQKKLIRRSRQLNRAVITATQMMESMISNPMPTRAEVM 302
Cdd:PRK14725 482 -TRRAFENLPRILLEAmrhpRFgVMIARGDLAVEVGFERLAEVQEEILWLCEAAHVPVIWATQVLESLAKKGLPSRAEIT 560
|
250
....*....|....*
gi 1393663876 303 DVANAVLdgTDAVML 317
Cdd:PRK14725 561 DAAMALR--AECVML 573
|
|
| |
