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Conserved domains on  [gi|1619369228|dbj|GCZ86254|]
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polysaccharide export outer membrane protein [Escherichia coli]

Protein Classification

polysaccharide biosynthesis/export family protein( domain architecture ID 12809731)

polysaccharide biosynthesis/export family protein similar to Escherichia coli polysialic acid transport protein KpsD involved in the translocation of the polysialic acid capsule across the outer membrane to the cell surface

Gene Ontology:  GO:0000271|GO:0015159|GO:0015774
TCDB:  1.B.18

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Wza COG1596
Periplasmic protein Wza involved in polysaccharide export, contains SLBB domain of the ...
82-252 1.15e-43

Periplasmic protein Wza involved in polysaccharide export, contains SLBB domain of the beta-grasp fold [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 441204 [Multi-domain]  Cd Length: 182  Bit Score: 153.52  E-value: 1.15e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1619369228  82 GATVGFNPDYILNPGDSIQVRLWGAFTFDGALQVDPKGNIFLPNVGPVKVAGVSNSQLNALVTSKVKEVYQsNVNVYASL 161
Cdd:COG1596    11 AGCAAVPPDYRLGPGDVLRITVWGEPELSGEVTVDPDGTISLPLIGPVKVAGLTLEELEEEIEERLAKYLK-DPQVTVSV 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1619369228 162 LQAQPVKVYVTGFVRNPGLYGGVTSDSLLNYLIKAGGVDpERGSYVDIVVKRGNR-VRSNVNLYDFLLNGKLGLS-QFAD 239
Cdd:COG1596    90 AEYRSRRVYVLGEVNRPGRYPLSSGLTLLDAIALAGGLT-ERADLRNVQLIRGGKeVVYTVDLYDLLLGGDPSQNiRLQP 168
                         170
                  ....*....|...
gi 1619369228 240 GDTIIVGPRQHTF 252
Cdd:COG1596   169 GDVIFVPEAGRRV 181
Wza super family cl34314
Periplasmic protein Wza involved in polysaccharide export, contains SLBB domain of the ...
461-532 3.20e-03

Periplasmic protein Wza involved in polysaccharide export, contains SLBB domain of the beta-grasp fold [Cell wall/membrane/envelope biogenesis];


The actual alignment was detected with superfamily member COG1596:

Pssm-ID: 441204 [Multi-domain]  Cd Length: 182  Bit Score: 38.73  E-value: 3.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1619369228 461 VMVHGEVLFPNAVSWQKGMTTEDYIEKCGGLTQKSGNARIIVIRQNG---AAVNAEDVDS---------LKPGDEIMVLP 528
Cdd:COG1596    97 VYVLGEVNRPGRYPLSSGLTLLDAIALAGGLTERADLRNVQLIRGGKevvYTVDLYDLLLggdpsqnirLQPGDVIFVPE 176

                  ....
gi 1619369228 529 KYES 532
Cdd:COG1596   177 AGRR 180
 
Name Accession Description Interval E-value
Wza COG1596
Periplasmic protein Wza involved in polysaccharide export, contains SLBB domain of the ...
82-252 1.15e-43

Periplasmic protein Wza involved in polysaccharide export, contains SLBB domain of the beta-grasp fold [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 441204 [Multi-domain]  Cd Length: 182  Bit Score: 153.52  E-value: 1.15e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1619369228  82 GATVGFNPDYILNPGDSIQVRLWGAFTFDGALQVDPKGNIFLPNVGPVKVAGVSNSQLNALVTSKVKEVYQsNVNVYASL 161
Cdd:COG1596    11 AGCAAVPPDYRLGPGDVLRITVWGEPELSGEVTVDPDGTISLPLIGPVKVAGLTLEELEEEIEERLAKYLK-DPQVTVSV 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1619369228 162 LQAQPVKVYVTGFVRNPGLYGGVTSDSLLNYLIKAGGVDpERGSYVDIVVKRGNR-VRSNVNLYDFLLNGKLGLS-QFAD 239
Cdd:COG1596    90 AEYRSRRVYVLGEVNRPGRYPLSSGLTLLDAIALAGGLT-ERADLRNVQLIRGGKeVVYTVDLYDLLLGGDPSQNiRLQP 168
                         170
                  ....*....|...
gi 1619369228 240 GDTIIVGPRQHTF 252
Cdd:COG1596   169 GDVIFVPEAGRRV 181
Poly_export pfam02563
Polysaccharide biosynthesis/export protein; This is a family of periplasmic proteins involved ...
88-157 2.56e-17

Polysaccharide biosynthesis/export protein; This is a family of periplasmic proteins involved in polysaccharide biosynthesis and/or export.


Pssm-ID: 426836 [Multi-domain]  Cd Length: 74  Bit Score: 76.46  E-value: 2.56e-17
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1619369228  88 NPDYILNPGDSIQVRLWGAFTFDGALQVDPKGNIFLPNVGPVKVAGVSNSQLNALVTSKVKEVYQS-NVNV 157
Cdd:pfam02563   4 PPDYRLGPGDVLRITVWGEPELSQEYTVDPDGTISLPLIGPVKVAGLTVEELEALIAERLAKYLRDpQVTV 74
PRK15078 PRK15078
polysaccharide export protein Wza; Provisional
91-280 1.57e-07

polysaccharide export protein Wza; Provisional


Pssm-ID: 237903 [Multi-domain]  Cd Length: 379  Bit Score: 53.48  E-value: 1.57e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1619369228  91 YILNPGDSIQVRLW---------GAF--TFDGALQVDPKGNIFLPNVGPVKVAGVSNSQLNALVT---SKVKEVYQSNVN 156
Cdd:PRK15078   85 YRVGPGDVLNVTVWdhpelttpaGQYrsASDTGNWVHADGTIFYPYIGKVHVAGKTVTEIRSDITgrlAKYIESPQVDVN 164
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1619369228 157 VYAslLQAQpvKVYVTGFVRNPGlYGGVTSD--SLLNYLIKAGGVDPErGSYVDIVVKRgNRVRSNVNLYDFLLNGKlgL 234
Cdd:PRK15078  165 IAA--FRSQ--KAYVTGEVNKSG-QQAITNVplTILDAINAAGGLTDD-ADWRNVVLTH-NGKEERISLQALMQNGD--L 235
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1619369228 235 SQ---FADGDTIIVgPR---QHTFsVQGDVFNSYDFEFRESSIPVTEALSWA 280
Cdd:PRK15078  236 SQnrlLYPGDILYV-PRnddLKVF-VMGEVKKQSTLKMDRSGMTLTEALGNA 285
Wza COG1596
Periplasmic protein Wza involved in polysaccharide export, contains SLBB domain of the ...
461-532 3.20e-03

Periplasmic protein Wza involved in polysaccharide export, contains SLBB domain of the beta-grasp fold [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 441204 [Multi-domain]  Cd Length: 182  Bit Score: 38.73  E-value: 3.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1619369228 461 VMVHGEVLFPNAVSWQKGMTTEDYIEKCGGLTQKSGNARIIVIRQNG---AAVNAEDVDS---------LKPGDEIMVLP 528
Cdd:COG1596    97 VYVLGEVNRPGRYPLSSGLTLLDAIALAGGLTERADLRNVQLIRGGKevvYTVDLYDLLLggdpsqnirLQPGDVIFVPE 176

                  ....
gi 1619369228 529 KYES 532
Cdd:COG1596   177 AGRR 180
 
Name Accession Description Interval E-value
Wza COG1596
Periplasmic protein Wza involved in polysaccharide export, contains SLBB domain of the ...
82-252 1.15e-43

Periplasmic protein Wza involved in polysaccharide export, contains SLBB domain of the beta-grasp fold [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 441204 [Multi-domain]  Cd Length: 182  Bit Score: 153.52  E-value: 1.15e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1619369228  82 GATVGFNPDYILNPGDSIQVRLWGAFTFDGALQVDPKGNIFLPNVGPVKVAGVSNSQLNALVTSKVKEVYQsNVNVYASL 161
Cdd:COG1596    11 AGCAAVPPDYRLGPGDVLRITVWGEPELSGEVTVDPDGTISLPLIGPVKVAGLTLEELEEEIEERLAKYLK-DPQVTVSV 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1619369228 162 LQAQPVKVYVTGFVRNPGLYGGVTSDSLLNYLIKAGGVDpERGSYVDIVVKRGNR-VRSNVNLYDFLLNGKLGLS-QFAD 239
Cdd:COG1596    90 AEYRSRRVYVLGEVNRPGRYPLSSGLTLLDAIALAGGLT-ERADLRNVQLIRGGKeVVYTVDLYDLLLGGDPSQNiRLQP 168
                         170
                  ....*....|...
gi 1619369228 240 GDTIIVGPRQHTF 252
Cdd:COG1596   169 GDVIFVPEAGRRV 181
Poly_export pfam02563
Polysaccharide biosynthesis/export protein; This is a family of periplasmic proteins involved ...
88-157 2.56e-17

Polysaccharide biosynthesis/export protein; This is a family of periplasmic proteins involved in polysaccharide biosynthesis and/or export.


Pssm-ID: 426836 [Multi-domain]  Cd Length: 74  Bit Score: 76.46  E-value: 2.56e-17
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1619369228  88 NPDYILNPGDSIQVRLWGAFTFDGALQVDPKGNIFLPNVGPVKVAGVSNSQLNALVTSKVKEVYQS-NVNV 157
Cdd:pfam02563   4 PPDYRLGPGDVLRITVWGEPELSQEYTVDPDGTISLPLIGPVKVAGLTVEELEALIAERLAKYLRDpQVTV 74
PRK15078 PRK15078
polysaccharide export protein Wza; Provisional
91-280 1.57e-07

polysaccharide export protein Wza; Provisional


Pssm-ID: 237903 [Multi-domain]  Cd Length: 379  Bit Score: 53.48  E-value: 1.57e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1619369228  91 YILNPGDSIQVRLW---------GAF--TFDGALQVDPKGNIFLPNVGPVKVAGVSNSQLNALVT---SKVKEVYQSNVN 156
Cdd:PRK15078   85 YRVGPGDVLNVTVWdhpelttpaGQYrsASDTGNWVHADGTIFYPYIGKVHVAGKTVTEIRSDITgrlAKYIESPQVDVN 164
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1619369228 157 VYAslLQAQpvKVYVTGFVRNPGlYGGVTSD--SLLNYLIKAGGVDPErGSYVDIVVKRgNRVRSNVNLYDFLLNGKlgL 234
Cdd:PRK15078  165 IAA--FRSQ--KAYVTGEVNKSG-QQAITNVplTILDAINAAGGLTDD-ADWRNVVLTH-NGKEERISLQALMQNGD--L 235
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1619369228 235 SQ---FADGDTIIVgPR---QHTFsVQGDVFNSYDFEFRESSIPVTEALSWA 280
Cdd:PRK15078  236 SQnrlLYPGDILYV-PRnddLKVF-VMGEVKKQSTLKMDRSGMTLTEALGNA 285
Wza COG1596
Periplasmic protein Wza involved in polysaccharide export, contains SLBB domain of the ...
461-532 3.20e-03

Periplasmic protein Wza involved in polysaccharide export, contains SLBB domain of the beta-grasp fold [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 441204 [Multi-domain]  Cd Length: 182  Bit Score: 38.73  E-value: 3.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1619369228 461 VMVHGEVLFPNAVSWQKGMTTEDYIEKCGGLTQKSGNARIIVIRQNG---AAVNAEDVDS---------LKPGDEIMVLP 528
Cdd:COG1596    97 VYVLGEVNRPGRYPLSSGLTLLDAIALAGGLTERADLRNVQLIRGGKevvYTVDLYDLLLggdpsqnirLQPGDVIFVPE 176

                  ....
gi 1619369228 529 KYES 532
Cdd:COG1596   177 AGRR 180
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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