|
Name |
Accession |
Description |
Interval |
E-value |
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
288-504 |
5.97e-68 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 218.24 E-value: 5.97e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 288 RAHNDFIANVSHDLKTPLAAITGFADILvNDSANLPPEKIKGFANHIVKETKRLSSLVTDTLEMTRQPLHLKKKKLNLTA 367
Cdd:COG2205 14 RLKSEFLANVSHELRTPLTSILGAAELL-LDEEDLSPEERRELLEIIRESAERLLRLIEDLLDLSRLESGKLSLELEPVD 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 368 LT---RDVLENFKLAIQEKSLQVTTQLDE--VTVKSNDKHLYAILKNLIENAIHYTPNGGKIYLCVTKIAGKATFSISDN 442
Cdd:COG2205 93 LAellEEAVEELRPLAEEKGIRLELDLPPelPLVYADPELLEQVLANLLDNAIKYSPPGGTITISARREGDGVRISVSDN 172
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2319844185 443 GPGLTEIEKTRIFERFYRADQTRDAEGTGLGLAIVKKNLTELGGQIDVVSVVGKGTTFTVTL 504
Cdd:COG2205 173 GPGIPEEELERIFERFYRGDNSRGEGGTGLGLAIVKRIVEAHGGTIWVESEPGGGTTFTVTL 234
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
279-504 |
4.14e-67 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 220.96 E-value: 4.14e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 279 DVTAYKVTTRAHNDFIANVSHDLKTPLAAITGFADILvNDSANLPPEKIKGFANHIVKETKRLSSLVTDTLEMTR---QP 355
Cdd:COG5002 154 DITELERLEQMRREFVANVSHELRTPLTSIRGYLELL-LDGAADDPEERREYLEIILEEAERLSRLVNDLLDLSRlesGE 232
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 356 LHLKKKKLNLTALTRDVLENFKLAIQEKSLQVTTQLDE--VTVKSNDKHLYAILKNLIENAIHYTPNGGKIYLCVTKIAG 433
Cdd:COG5002 233 LKLEKEPVDLAELLEEVVEELRPLAEEKGIELELDLPEdpLLVLGDPDRLEQVLTNLLDNAIKYTPEGGTITVSLREEDD 312
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2319844185 434 KATFSISDNGPGLTEIEKTRIFERFYRADQ--TRDAEGTGLGLAIVKKNLTELGGQIDVVSVVGKGTTFTVTL 504
Cdd:COG5002 313 QVRISVRDTGIGIPEEDLPRIFERFYRVDKsrSRETGGTGLGLAIVKHIVEAHGGRIWVESEPGKGTTFTITL 385
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
288-504 |
2.13e-63 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 209.38 E-value: 2.13e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 288 RAHNDFIANVSHDLKTPLAAITGFADILVNDsanlPPEKIKGFANHIVKETKRLSSLVTDTLEMTRQPLHLKKKKLNLT- 366
Cdd:COG0642 108 EAKSRFLANVSHELRTPLTAIRGYLELLLEE----LDEEQREYLETILRSADRLLRLINDLLDLSRLEAGKLELEPEPVd 183
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 367 --ALTRDVLENFKLAIQEKSLQVTTQLDE--VTVKSNDKHLYAILKNLIENAIHYTPNGGKIYLCVTKIAGKATFSISDN 442
Cdd:COG0642 184 laELLEEVVELFRPLAEEKGIELELDLPDdlPTVRGDPDRLRQVLLNLLSNAIKYTPEGGTVTVSVRREGDRVRISVEDT 263
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2319844185 443 GPGLTEIEKTRIFERFYRADQTRDAEGTGLGLAIVKKNLTELGGQIDVVSVVGKGTTFTVTL 504
Cdd:COG0642 264 GPGIPPEDLERIFEPFFRTDPSRRGGGTGLGLAIVKRIVELHGGTIEVESEPGKGTTFTVTL 325
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
292-504 |
1.19e-43 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 161.49 E-value: 1.19e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 292 DFIANVSHDLKTPLAAITGFADILVNDSANLPPEKIKGFANHIVKETKRLSSLVTDTLEMTRQPLHLKKKKLN-LTALTR 370
Cdd:COG4251 284 QFAYVASHDLREPLRKISGFSQLLEEDYGDKLDEEGREYLERIRDAAERMQALIDDLLAYSRVGRQELEFEPVdLNELLE 363
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 371 DVLENFKLAIQEKSLQVTTQlDEVTVKSNDKHLYAILKNLIENAIHYTPNG--GKIYLCVTKIAGKATFSISDNGPGLTE 448
Cdd:COG4251 364 EVLEDLEPRIEERGAEIEVG-PLPTVRGDPTLLRQVFQNLISNAIKYSRPGepPRIEIGAEREGGEWVFSVRDNGIGIDP 442
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 2319844185 449 IEKTRIFERFYRADQTRDAEGTGLGLAIVKKNLTELGGQIDVVSVVGKGTTFTVTL 504
Cdd:COG4251 443 EYAEKIFEIFQRLHSRDEYEGTGIGLAIVKKIVERHGGRIWVESEPGEGATFYFTL 498
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
100-504 |
7.53e-40 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 148.96 E-value: 7.53e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 100 TLFETVIVIIFAGVIYVIGLGQFYLANKKRLIFEADTIAKIKNIRRSPLTQSYLISEddnkITTELNHLGETIQHQAESS 179
Cdd:COG5000 10 LLLLIALLLLLLALWLALLLARRLTRPLRRLAEATRAVAAGDLSVRLPVTGDDEIGE----LARAFNRMTDQLKEQREEL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 180 TPAKKNLYAFIEFFEFPIFIYDLKGTIRRSNASFQ------NEFMATKNLDVFSPYSDVLQFLVNKMLKPTRQEQTFYFE 253
Cdd:COG5000 86 EERRRYLETILENLPAGVIVLDADGRITLANPAAErllgipLEELIGKPLEELLPELDLAELLREALERGWQEEIELTRD 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 254 KINayyTVTVQPIEALERRIMVTMIDVTAYKVTTR--AHNDFIANVSHDLKTPLAAITGFADIL---VNDSANLPPEKIK 328
Cdd:COG5000 166 GRR---TLLVRASPLRDDGYVIVFDDITELLRAERlaAWGELARRIAHEIKNPLTPIQLSAERLrrkLADKLEEDREDLE 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 329 GFANHIVKETKRLSSLVTDTLEMTRQPLHLKKKKLNlTALTRDVLENFKLAIQEKSLQVTTQLDE--VTVKSNDKHLYAI 406
Cdd:COG5000 243 RALDTIIRQVDRLKRIVDEFLDFARLPEPQLEPVDL-NELLREVLALYEPALKEKDIRLELDLDPdlPEVLADRDQLEQV 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 407 LKNLIENAIHYTPNGGKIYLCVTKIAGKATFSISDNGPGLTEIEKTRIFERFYradqTRDAEGTGLGLAIVKKNLTELGG 486
Cdd:COG5000 322 LINLLKNAIEAIEEGGEIEVSTRREDGRVRIEVSDNGPGIPEEVLERIFEPFF----TTKPKGTGLGLAIVKKIVEEHGG 397
|
410
....*....|....*...
gi 2319844185 487 QIDVVSVVGKGTTFTVTL 504
Cdd:COG5000 398 TIELESRPGGGTTFTIRL 415
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
269-504 |
2.15e-36 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 139.76 E-value: 2.15e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 269 LERRIM------VTMI--DVTAYKVTTRAHNDFIANVSHDLKTPLAAITGFADILVNDSANLPP-EKikgfANHIVKE-T 338
Cdd:PRK11006 175 LEIRVMpytegqLLMVarDVTQMHQLEGARRNFFANVSHELRTPLTVLQGYLEMMQDQPLEGALrEK----ALHTMREqT 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 339 KRLSSLVTDTLEMTR---QPLHLKKKKLNLTALTRdVLENFKLAIQEKSLQVTTQLDE-VTVKSNDKHLYAILKNLIENA 414
Cdd:PRK11006 251 QRMEGLVKQLLTLSKieaAPTIDLNEKVDVPMMLR-VLEREAQTLSQGKHTITFEVDNsLKVFGNEDQLRSAISNLVYNA 329
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 415 IHYTPNGGKIYLCVTKIAGKATFSISDNGPGLTEIEKTRIFERFYRADQ--TRDAEGTGLGLAIVKKNLTELGGQIDVVS 492
Cdd:PRK11006 330 VNHTPEGTHITVRWQRVPQGAEFSVEDNGPGIAPEHIPRLTERFYRVDKarSRQTGGSGLGLAIVKHALSHHDSRLEIES 409
|
250
....*....|..
gi 2319844185 493 VVGKGTTFTVTL 504
Cdd:PRK11006 410 EVGKGTRFSFVL 421
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
201-504 |
4.21e-36 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 137.29 E-value: 4.21e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 201 DLKGTIRRSNASFQNEF------MATKNLDVFSPYSDVLQFLVNKMLK----PTRQEQTFYF---EKINAYYTVTVQPIE 267
Cdd:COG3852 24 DADGRITYVNPAAERLLglsaeeLLGRPLAELFPEDSPLRELLERALAegqpVTEREVTLRRkdgEERPVDVSVSPLRDA 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 268 ALERRIMVTMIDVTAYKVTTR--AHND-------FIANVSHDLKTPLAAITGFADILvndSANLPPEKIKGFANHIVKET 338
Cdd:COG3852 104 EGEGGVLLVLRDITERKRLERelRRAEklaavgeLAAGLAHEIRNPLTGIRGAAQLL---ERELPDDELREYTQLIIEEA 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 339 KRLSSLVTDTLEMTRqPLHLKKKKLNLTALTRDVLENFKLAIQeKSLQVTTQLDE--VTVKSNDKHLY-AILkNLIENAI 415
Cdd:COG3852 181 DRLNNLVDRLLSFSR-PRPPEREPVNLHEVLERVLELLRAEAP-KNIRIVRDYDPslPEVLGDPDQLIqVLL-NLVRNAA 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 416 HYTPNGGKIYLcVTKIAGKAT-----------FSISDNGPGLTEIEKTRIFERFYRadqTRDaEGTGLGLAIVKKNLTEL 484
Cdd:COG3852 258 EAMPEGGTITI-RTRVERQVTlgglrprlyvrIEVIDNGPGIPEEILDRIFEPFFT---TKE-KGTGLGLAIVQKIVEQH 332
|
330 340
....*....|....*....|
gi 2319844185 485 GGQIDVVSVVGKGTTFTVTL 504
Cdd:COG3852 333 GGTIEVESEPGKGTTFRIYL 352
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
399-504 |
1.30e-33 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 122.76 E-value: 1.30e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 399 NDKHLYAILKNLIENAIHYTPNGGKIYLCVTKIAGKATFSISDNGPGLTEIEKTRIFERFYRADQT-RDAEGTGLGLAIV 477
Cdd:smart00387 2 DPDRLRQVLSNLLDNAIKYTPEGGRITVTLERDGDHVEITVEDNGPGIPPEDLEKIFEPFFRTDKRsRKIGGTGLGLSIV 81
|
90 100
....*....|....*....|....*..
gi 2319844185 478 KKNLTELGGQIDVVSVVGKGTTFTVTL 504
Cdd:smart00387 82 KKLVELHGGEISVESEPGGGTTFTITL 108
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
295-504 |
1.62e-33 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 130.30 E-value: 1.62e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 295 ANVSHDLKTPLAAITGFADILVND-SANLPPEKIKGFANHIVKETKRLSSLVTDTLEMTRQPLHLKKKKLNLTALtRDVL 373
Cdd:COG4191 147 AGIAHEINNPLAAILGNAELLRRRlEDEPDPEELREALERILEGAERAAEIVRSLRAFSRRDEEEREPVDLNELI-DEAL 225
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 374 ENFKLAIQEKSLQVTTQLDE--VTVKSNDKHLYAILKNLIENAIHYTPNG--GKIYLCVTKIAGKATFSISDNGPGLTEI 449
Cdd:COG4191 226 ELLRPRLKARGIEVELDLPPdlPPVLGDPGQLEQVLLNLLINAIDAMEEGegGRITISTRREGDYVVISVRDNGPGIPPE 305
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 2319844185 450 EKTRIFERFYradqT--RDAEGTGLGLAIVKKNLTELGGQIDVVSVVGKGTTFTVTL 504
Cdd:COG4191 306 VLERIFEPFF----TtkPVGKGTGLGLSISYGIVEKHGGRIEVESEPGGGTTFTITL 358
|
|
| HATPase |
cd00075 |
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ... |
403-504 |
2.23e-33 |
|
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ATPase (HATPase) domains of several ATP-binding proteins such as histidine kinase, DNA gyrase B, topoisomerases, heat shock protein 90 (HSP90), phytochrome-like ATPases and DNA mismatch repair proteins. Domains belonging to this superfamily are also referred to as GHKL (gyrase, heat-shock protein 90, histidine kinase, MutL) ATPase domains.
Pssm-ID: 340391 [Multi-domain] Cd Length: 102 Bit Score: 121.94 E-value: 2.23e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 403 LYAILKNLIENAIHYTPNGGKIYLCVTKIAGKATFSISDNGPGLTEIEKTRIFERFYRADQTRDAEGTGLGLAIVKKNLT 482
Cdd:cd00075 1 LEQVLSNLLDNALKYSPPGGTIEISLRQEGDGVVLEVEDNGPGIPEEDLERIFERFYRGDKSREGGGTGLGLAIVRRIVE 80
|
90 100
....*....|....*....|..
gi 2319844185 483 ELGGQIDVVSVVGKGTTFTVTL 504
Cdd:cd00075 81 AHGGRITVESEPGGGTTFTVTL 102
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
299-504 |
7.27e-32 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 127.65 E-value: 7.27e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 299 HDLKTPLAAITGFADILVNDsanLPPEKIKGFANHIVKETKRLSSLVTDTLEMTR---QPLHLKKKKLNLTALTRDVLEN 375
Cdd:PRK11100 265 HELKSPLAAIRGAAELLQED---PPPEDRARFTGNILTQSARLQQLIDRLLELARleqRQELEVLEPVALAALLEELVEA 341
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 376 FKLAIQEKSLQVTTQLDEVTVKSNDKHLYAILKNLIENAIHYTPNGGKIYLCVTKIAGKATFSISDNGPGLTEIEKTRIF 455
Cdd:PRK11100 342 REAQAAAKGITLRLRPDDARVLGDPFLLRQALGNLLDNAIDFSPEGGTITLSAEVDGEQVALSVEDQGPGIPDYALPRIF 421
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 2319844185 456 ERFY---RADQTRdaEGTGLGLAIVKKNLTELGGQIDVVSVVGKGTTFTVTL 504
Cdd:PRK11100 422 ERFYslpRPANGR--KSTGLGLAFVREVARLHGGEVTLRNRPEGGVLATLTL 471
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
294-504 |
1.08e-30 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 122.75 E-value: 1.08e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 294 IANVSHDLKTPLAAiTGFA----DILVNDSAN-LPPEKIKGFANHIVKETKRLSSLVTDTLEMTRQPLHLKKKKLNLTAL 368
Cdd:PRK09303 155 LAMLAHDLRTPLTA-ASLAletlELGQIDEDTeLKPALIEQLQDQARRQLEEIERLITDLLEVGRTRWEALRFNPQKLDL 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 369 TR---DVLENFKLAIQEKSLQVTTQL--DEVTVKSNDKHLYAILKNLIENAIHYTPNGGKIYLCVT-KIAGKATFSISDN 442
Cdd:PRK09303 234 GSlcqEVILELEKRWLAKSLEIQTDIpsDLPSVYADQERIRQVLLNLLDNAIKYTPEGGTITLSMLhRTTQKVQVSICDT 313
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2319844185 443 GPGLTEIEKTRIFERFYRADQTRDAEGTGLGLAIVKKNLTELGGQIDVVSVVGKGTTFTVTL 504
Cdd:PRK09303 314 GPGIPEEEQERIFEDRVRLPRDEGTEGYGIGLSVCRRIVRVHYGQIWVDSEPGQGSCFHFTL 375
|
|
| KinD |
COG5808 |
Sporulation sensor histidine kinase D [Cell cycle control, cell division, chromosome ... |
293-504 |
1.11e-29 |
|
Sporulation sensor histidine kinase D [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444510 [Multi-domain] Cd Length: 454 Bit Score: 121.01 E-value: 1.11e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 293 FIANVSHDLKTPLAAITGFADILVNDSANLPPEKikgFANHIVKETKRLSSLVTDTLEMTRqPLHLKKKKLNLTALTRDV 372
Cdd:COG5808 244 FAASTAHEIRNPLTSIKGFIQLLQEKYPELEDQK---YFDIIQEEIQRINQIVSEFLVLGK-PTAKKLELDDLNELIEEI 319
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 373 LENFKLAIQEKSLQVTTQL--DEVTVKSNDKHLYAILKNLIENAIHYTPNGGKIYLCVTKIAGKATFSISDNGPGLTEIE 450
Cdd:COG5808 320 LSIIDSEANLKNIRVEKQSldEPLHIKCDKDRIKQVLLNLIKNAIEAMKEGGKLTISIENDDEKAVIEVIDNGEGIPEDI 399
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 2319844185 451 KTRIFERFYradqTRDAEGTGLGLAIVKKNLTELGGQIDVVSVVGKGTTFTVTL 504
Cdd:COG5808 400 IDEIFEPFV----TTKEGGTGLGLSVCKRIVEMHGGEIDIESEEGKGTTFTIRL 449
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
401-504 |
3.54e-28 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 107.84 E-value: 3.54e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 401 KHLYAILKNLIENAIHYTPNGGKIYLCVTKiAGKATFSISDNGPGLTEIEKTRIFERFYRADqTRDAEGTGLGLAIVKKN 480
Cdd:pfam02518 4 LRLRQVLSNLLDNALKHAAKAGEITVTLSE-GGELTLTVEDNGIGIPPEDLPRIFEPFSTAD-KRGGGGTGLGLSIVRKL 81
|
90 100
....*....|....*....|....
gi 2319844185 481 LTELGGQIDVVSVVGKGTTFTVTL 504
Cdd:pfam02518 82 VELLGGTITVESEPGGGTTVTLTL 105
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
201-504 |
7.12e-28 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 116.23 E-value: 7.12e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 201 DLKGTIRRSNASF-------QNEFMATKNLDVFSPY-SDVLQFLVNKML--KPTRQEQTFYFEKINAYYTVTV--QPIEA 268
Cdd:COG5809 158 DLDGRIIYANPAAckllgisIEELIGKSILELIHSDdQENVAAFISQLLkdGGIAQGEVRFWTKDGRWRLLEAsgAPIKK 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 269 LERRIMVTMI--DVTAYKVTTRA--HND-------FIANVSHDLKTPLAAITGFADILvNDSANlppEKIKGFANHIVKE 337
Cdd:COG5809 238 NGEVDGIVIIfrDITERKKLEELlrKSEklsvvgeLAAGIAHEIRNPLTSLKGFIQLL-KDTID---EEQKTYLDIMLSE 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 338 TKRLSSLVTDTLEMTRqPLHLKKKKLNLTALTRDVLENFKLAIQEKSLQVTTQL--DEVTVKSNDKHLYAILKNLIENAI 415
Cdd:COG5809 314 LDRIESIISEFLVLAK-PQAIKYEPKDLNTLIEEVIPLLQPQALLKNVQIELELedDIPDILGDENQLKQVFINLLKNAI 392
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 416 HYTPNGGKIYLCVTKIA-GKATFSISDNGPGLTEIEKTRIFERFYradqTRDAEGTGLGLAIVKKNLTELGGQIDVVSVV 494
Cdd:COG5809 393 EAMPEGGNITIETKAEDdDKVVISVTDEGCGIPEERLKKLGEPFY----TTKEKGTGLGLMVSYKIIEEHGGKITVESEV 468
|
330
....*....|
gi 2319844185 495 GKGTTFTVTL 504
Cdd:COG5809 469 GKGTTFSITL 478
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
293-504 |
9.43e-26 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 110.83 E-value: 9.43e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 293 FIANVSHDLKTPLAAITGFADILVNDSANLPPEKikgFANHIVKETKRLSSLVTDTLEMTRqPLHLKKKKLNLTALTRDV 372
Cdd:PRK11360 393 LVAGVAHEIRNPLTAIRGYVQIWRQQTSDPPSQE---YLSVVLREVDRLNKVIDQLLEFSR-PRESQWQPVSLNALVEEV 468
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 373 LENFKLAIQEKSLQVTTQLDE--VTVKSNDKHLYAILKNLIENAIHYTPNGGKIYLCVTKIA-GKATFSISDNGPGLTEI 449
Cdd:PRK11360 469 LQLFQTAGVQARVDFETELDNelPPIWADPELLKQVLLNILINAVQAISARGKIRIRTWQYSdGQVAVSIEDNGCGIDPE 548
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 2319844185 450 EKTRIFERFYradqTRDAEGTGLGLAIVKKNLTELGGQIDVVSVVGKGTTFTVTL 504
Cdd:PRK11360 549 LLKKIFDPFF----TTKAKGTGLGLALSQRIINAHGGDIEVESEPGVGTTFTLYL 599
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
406-504 |
1.02e-24 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 98.33 E-value: 1.02e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 406 ILKNLIENAIHYTPNGGkIYLCVTKIA-----GKATFSISDNGPGLTEIEKTRIFERFYRADQ--TRDAEGTGLGLAIVK 478
Cdd:cd16922 4 ILLNLLGNAIKFTEEGE-VTLRVSLEEeeedgVQLRFSVEDTGIGIPEEQQARLFEPFSQADSstTRKYGGTGLGLAISK 82
|
90 100
....*....|....*....|....*..
gi 2319844185 479 KnLTEL-GGQIDVVSVVGKGTTFTVTL 504
Cdd:cd16922 83 K-LVELmGGDISVESEPGQGSTFTFTL 108
|
|
| cztS_silS_copS |
TIGR01386 |
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain ... |
292-504 |
3.72e-24 |
|
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.
Pssm-ID: 273593 [Multi-domain] Cd Length: 457 Bit Score: 105.16 E-value: 3.72e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 292 DFIANVSHDLKTPLAAITGFADILVNDSANLPPEKIKGFANhiVKETKRLSSLVTDTLEMTRQPLHLKKKKLNLTAL--- 368
Cdd:TIGR01386 243 QFSADLAHELRTPLTNLLGQTQVALSQPRTGEEYREVLESN--LEELERLSRMVSDMLFLARADNGQLALERVRLDLaae 320
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 369 TRDVLENFKLAIQEKSLQVTTQLDEVTVKSNDKHLYAIlKNLIENAIHYTPNGGKIYLCVTKIAGKATFSISDNGPGLTE 448
Cdd:TIGR01386 321 LAKVAEYFEPLAEERGVRIRVEGEGLVRGDPQMFRRAI-SNLLSNALRHTPDGGTITVRIERRSDEVRVSVSNPGPGIPP 399
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 2319844185 449 IEKTRIFERFYRAD--QTRDAEGTGLGLAIVKKNLTELGGQIDVVSVVGKgTTFTVTL 504
Cdd:TIGR01386 400 EHLSRLFDRFYRVDpaRSNSGEGTGLGLAIVRSIMEAHGGRASAESPDGK-TRFILRF 456
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
394-504 |
3.54e-23 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 94.39 E-value: 3.54e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 394 VTVKSNDKHLYAILKNLIENAIHYTPNGGKIYLCVTKIAGkATFSISDNGPGLTEIEKTRIFERFYRADqTRDAEGTGLG 473
Cdd:cd16940 5 IQVQGDALLLFLLLRNLVDNAVRYSPQGSRVEIKLSADDG-AVIRVEDNGPGIDEEELEALFERFYRSD-GQNYGGSGLG 82
|
90 100 110
....*....|....*....|....*....|..
gi 2319844185 474 LAIVKKnLTEL-GGQIDVVSVVGKGTTFTVTL 504
Cdd:cd16940 83 LSIVKR-IVELhGGQIFLGNAQGGGLEAWVRL 113
|
|
| KinC |
COG5807 |
Sporulation sensor histidine kinase C [Cell cycle control, cell division, chromosome ... |
295-504 |
8.23e-22 |
|
Sporulation sensor histidine kinase C [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444509 [Multi-domain] Cd Length: 358 Bit Score: 96.78 E-value: 8.23e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 295 ANVSHDLKTPLAAITGFADILVNDSanlPPEKIKGFANHIVKETKRLSSLVTDTLEMTRqPLHLKKKKLNLTALTRDV-- 372
Cdd:COG5807 152 AGIAHEIRNPLTSIKGFLQLLQESR---EDSEREEYFNIIISEIDRINTIITELLVLSK-PKKFNFKKLNLNDVLEDVia 227
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 373 LENFKLAIQEKSLQVTTQLDEVTVKSNDKHLYAILKNLIENAIHYTPNGGKIYLCVTKIAGKATFSISDNGPGLTEIEKT 452
Cdd:COG5807 228 LLSTEAILKNISIKYDLADDEPVINGDKNQLKQVFINLIKNAIEAMETGGNITIKTYVEGDFVVISVKDEGIGIPEEVLE 307
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 2319844185 453 RIFERFYradqTRDAEGTGLGLAIVKKNLTELGGQIDVVSVVGKGTTFTVTL 504
Cdd:COG5807 308 KIGEPFF----TTKEEGTGLGLSICKKIIEEHNGTIEVESKPGKGTTFTIYL 355
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
295-504 |
1.21e-21 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 97.55 E-value: 1.21e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 295 ANVSHDLKTPLAAITGFADILvndSANLPPE-KIKGFANHIVKETKRLSSLVTDTLEMTRqPLHLKKKKLNLTALTRDVL 373
Cdd:PRK10364 242 AGVAHEIRNPLSSIKGLAKYF---AERAPAGgEAHQLAQVMAKEADRLNRVVSELLELVK-PTHLALQAVDLNDLINHSL 317
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 374 ENFKLAIQEKSLQVTTQLDEV--TVKSNDKHLYAILKNLIENAIHYTPNGGKIYLCVTKIAGKATFSISDNGPGLTEIEK 451
Cdd:PRK10364 318 QLVSQDANSREIQLRFTANDTlpEIQADPDRLTQVLLNLYLNAIQAIGQHGVISVTASESGAGVKISVTDSGKGIAADQL 397
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 2319844185 452 TRIFERFYradqTRDAEGTGLGLAIVKKNLTELGGQIDVVSVVGKGTTFTVTL 504
Cdd:PRK10364 398 EAIFTPYF----TTKAEGTGLGLAVVHNIVEQHGGTIQVASQEGKGATFTLWL 446
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
200-504 |
5.59e-21 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 95.57 E-value: 5.59e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 200 YDLKGTIRRSNASFQNEF------MATKNLDVFSPYSDVLQFL-VNKMLKPTRQEQTFYFEKINA-----YYTVTVQP-- 265
Cdd:COG5805 173 IDTDGRILFINESIERLFgapreeLIGKNLLELLHPCDKEEFKeRIESITEVWQEFIIEREIITKdgrirYFEAVIVPli 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 266 -IEALERRIMVTMIDVTAYKVTTR--AHND-------FIANVSHDLKTPLAAITGFADILVNDsanlpPEKIKGFANHIV 335
Cdd:COG5805 253 dTDGSVKGILVILRDITEKKEAEElmARSEklsiagqLAAGIAHEIRNPLTSIKGFLQLLQPG-----IEDKEEYFDIML 327
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 336 KETKRLSSLVTDTLEMTRqPLHLKKKKLNLTALTRDV--LENFKLAIQEKSLqVTTQLDEV-TVKSNDKHLYAILKNLIE 412
Cdd:COG5805 328 SELDRIESIISEFLALAK-PQAVNKEKENINELIQDVvtLLETEAILHNIQI-RLELLDEDpFIYCDENQIKQVFINLIK 405
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 413 NAIHYTPNGGKIYLCVTKIAGKATFSISDNGPGLTEIEKTRIFERFYradqTRDAEGTGLGLAIVKKNLTELGGQIDVVS 492
Cdd:COG5805 406 NAIEAMPNGGTITIHTEEEDNSVIIRVIDEGIGIPEERLKKLGEPFF----TTKEKGTGLGLMVSYKIIENHNGTIDIDS 481
|
330
....*....|..
gi 2319844185 493 VVGKGTTFTVTL 504
Cdd:COG5805 482 KVGKGTTFTITL 493
|
|
| KinB |
COG5806 |
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome ... |
295-504 |
5.66e-21 |
|
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444508 [Multi-domain] Cd Length: 412 Bit Score: 94.93 E-value: 5.66e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 295 ANVSHDLKTPLAAITGFADILvnDSANLPPEKIKGFANHIVKETKRLSSLVTDTLEMTRQPLHLKKKKLNLTALTR--DV 372
Cdd:COG5806 206 ASIAHEVRNPLTVVRGFIQLL--QEPELSDEKRKQYIRIALEELDRAEAIITDYLTFAKPQPEKLEKIDVSEELEHviDV 283
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 373 LENFKLAiqeKSLQVTTQLDE-VTVKSNDKHLYAILKNLIENAIHYTPNGGKIYLCVTKIAGKATFSISDNGPGLTEIEK 451
Cdd:COG5806 284 LSPYANM---NNVEIQTELEPgLYIEGDRQKLQQCLINIIKNGIEAMPNGGTLTIDVSIDKNKVIISIKDTGVGMTKEQL 360
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 2319844185 452 TRIFERFYradqTRDAEGTGLGLAIVKKNLTELGGQIDVVSVVGKGTTFTVTL 504
Cdd:COG5806 361 ERLGEPYF----STKEKGTGLGTMVSYRIIEAMNGTIRVESEVGKGTTFTITL 409
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
403-501 |
8.02e-21 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 87.64 E-value: 8.02e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 403 LYAILKNLIENAIHYTPNGGKIYLCVTKIAGKATFSISDNGPGLTEIEKTRIFERFYRAD--QTRDAEGTGLGLAIVKKN 480
Cdd:cd16952 1 LRSAFSNLVSNAVKYTPPSDTITVRWSQEESGARLSVEDTGPGIPPEHIPRLTERFYRVDieRCRNTGGTGLGLAIVKHV 80
|
90 100
....*....|....*....|.
gi 2319844185 481 LTELGGQIDVVSVVGKGTTFT 501
Cdd:cd16952 81 MSRHDARLLIASELGKGSRFT 101
|
|
| cpxA |
PRK09470 |
envelope stress sensor histidine kinase CpxA; |
264-477 |
1.21e-20 |
|
envelope stress sensor histidine kinase CpxA;
Pssm-ID: 236532 [Multi-domain] Cd Length: 461 Bit Score: 94.61 E-value: 1.21e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 264 QPIEALERriMVTmidvtaykvttrAHNDFIANVSHDLKTPLAAI---TGFADILVNDSANLppekikgfaNHIVKETKR 340
Cdd:PRK09470 231 QMVTALER--MMT------------SQQRLLSDISHELRTPLTRLqlaTALLRRRQGESKEL---------ERIETEAQR 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 341 LSSLVTDTLEMTRQPLHLKKKKLNLTA--LTRDVLEN--FKLAIQEKSLQVTTQLDEVTVKSNDKHLYAILKNLIENAIH 416
Cdd:PRK09470 288 LDSMINDLLVLSRNQQKNHLERETFKAnsLWSEVLEDakFEAEQMGKSLTVSAPPGPWPINGNPNALASALENIVRNALR 367
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2319844185 417 YTPNggKIYLCVTKIAGKATFSISDNGPGLTEIEKTRIFERFYRADQTRDAE--GTGLGLAIV 477
Cdd:PRK09470 368 YSHT--KIEVAFSVDKDGLTITVDDDGPGVPEEEREQIFRPFYRVDEARDREsgGTGLGLAIV 428
|
|
| PRK11091 |
PRK11091 |
aerobic respiration control sensor protein ArcB; Provisional |
292-504 |
1.90e-20 |
|
aerobic respiration control sensor protein ArcB; Provisional
Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 95.01 E-value: 1.90e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 292 DFIANVSHDLKTPLAAITGFADILVNdsANLPPEKIKGFAN-HIVKETkrLSSLVTDTLEM---TRQPLHLKKKKLNLTA 367
Cdd:PRK11091 285 TFISTISHELRTPLNGIVGLSRILLD--TELTAEQRKYLKTiHVSAIT--LGNIFNDIIDMdkmERRKLQLDNQPIDFTD 360
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 368 LTRDvLENF-KLAIQEKSLQVTTQLDE---VTVKSNDKHLYAILKNLIENAIHYTPNGGKIYLCVTKIAGKATFSISDNG 443
Cdd:PRK11091 361 FLAD-LENLsGLQAEQKGLRFDLEPLLplpHKVITDGTRLRQILWNLISNAVKFTQQGGVTVRVRYEEGDMLTFEVEDSG 439
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2319844185 444 PGLTEIEKTRIFERFYRADQ---TRDAEGTGLGLAIVKKNLTELGGQIDVVSVVGKGTTFTVTL 504
Cdd:PRK11091 440 IGIPEDELDKIFAMYYQVKDshgGKPATGTGIGLAVSKRLAQAMGGDITVTSEEGKGSCFTLTI 503
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
384-504 |
9.76e-20 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 91.06 E-value: 9.76e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 384 SLQVTTQLDEVTVKSNDkhLYAILKNLIENAIHYTPNG----GKIYLCVTKIAGKATFSISDNGPGLTEIEKTRIFERFY 459
Cdd:COG3290 265 TIDIDSDLPDLPLSDTD--LVTILGNLLDNAIEAVEKLpeeeRRVELSIRDDGDELVIEVEDSGPGIPEELLEKIFERGF 342
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 2319844185 460 radQTRDAEGTGLGLAIVKKNLTELGGQIDVVSVVGKGTTFTVTL 504
Cdd:COG3290 343 ---STKLGEGRGLGLALVKQIVEKYGGTIEVESEEGEGTVFTVRL 384
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
406-504 |
1.69e-19 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 83.70 E-value: 1.69e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 406 ILKNLIENAIHYTPNGGKIYLCVTKI-AGKATFSISDNGPGLTEIEKTRIFERFYRADQ--TRDAEGTGLGLAIVKKNLT 482
Cdd:cd16925 8 VVLNLLSNAFKFTPDGGRIRCILEKFrLNRFLLTVSDSGPGIPPNLREEIFERFRQGDGssTRAHGGTGLGLSIVKEFVE 87
|
90 100
....*....|....*....|..
gi 2319844185 483 ELGGQIDVVSVVGKGTTFTVTL 504
Cdd:cd16925 88 LHGGTVTVSDAPGGGALFQVEL 109
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
403-488 |
5.21e-19 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 81.99 E-value: 5.21e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 403 LYAILKNLIENAIHYTPngGKIYLCVTKIAGKATFSISDNGPGLTEIEKTRIFERFYRADQTRDAE--GTGLGLAIVKKN 480
Cdd:cd16949 1 LARALENVLRNALRYSP--SKILLDISQDGDQWTITITDDGPGVPEDQLEQIFLPFYRVDSARDREsgGTGLGLAIAERA 78
|
....*...
gi 2319844185 481 LTELGGQI 488
Cdd:cd16949 79 IEQHGGKI 86
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
292-488 |
6.21e-19 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 89.31 E-value: 6.21e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 292 DFIANVSHDLKTPLAAITGFADILVNDSANLPPEKIkgfaNHIVKETKRLSSLVTD--TLEMT-RQPLHLKKKKLNLTAL 368
Cdd:PRK10549 242 DFMADISHELRTPLAVLRGELEAIQDGVRKFTPESV----ASLQAEVGTLTKLVDDlhQLSLSdEGALAYRKTPVDLVPL 317
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 369 TRDVLENFKLAIQEKSLQVTTQL-DEVTVKSNDKHLYAILKNLIENAIHYTPNGGKIYLCVTKIAGKATFSISDNGPGLT 447
Cdd:PRK10549 318 LEVAGGAFRERFASRGLTLQLSLpDSATVFGDPDRLMQLFNNLLENSLRYTDSGGSLHISAEQRDKTLRLTFADSAPGVS 397
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 2319844185 448 EIEKTRIFERFYRADQTRD--AEGTGLGLAIVkKNLTEL-GGQI 488
Cdd:PRK10549 398 DEQLQKLFERFYRTEGSRNraSGGSGLGLAIC-LNIVEAhNGRI 440
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
294-504 |
2.63e-17 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 85.08 E-value: 2.63e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 294 IANVSHDLKTPLAAITGFADILVNDSANLppeKIKGFANHIVKETKRLSSLVTDTLEMTRQPLHLKKKKLNLTALTRdVL 373
Cdd:PRK15347 402 LTTISHEIRTPLNGVLGALELLQNTPLTA---EQMDLADTARQCTLSLLAIINNLLDFSRIESGQMTLSLEETALLP-LL 477
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 374 ENFKLAIQ----EKSLQVTTQL-DEV--TVKSNDKHLYAILKNLIENAIHYTPNGGkIYLCVTKIAGKATFSISDNGPGL 446
Cdd:PRK15347 478 DQAMLTIQgpaqSKSLTLRTFVgAHVplYLHLDSLRLRQILVNLLGNAVKFTETGG-IRLRVKRHEQQLCFTVEDTGCGI 556
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 2319844185 447 TEIEKTRIFERFYRADQTrdAEGTGLGLAIVKKNLTELGGQIDVVSVVGKGTTFTVTL 504
Cdd:PRK15347 557 DIQQQQQIFTPFYQADTH--SQGTGLGLTIASSLAKMMGGELTLFSTPGVGSCFSLVL 612
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
398-504 |
4.17e-17 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 76.94 E-value: 4.17e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 398 SNDKHLYAILKNLIENAIHYTPNGGKIYLCVTKIAGKATFSISDNGPGLTEIEKTRIFERFYRADQTR-DAEGTGLGLAI 476
Cdd:cd16948 1 TDAKWLSFIIGQIVSNALKYSKQGGKIEIYSETNEQGVVLSIKDFGIGIPEEDLPRVFDKGFTGENGRnFQESTGMGLYL 80
|
90 100
....*....|....*....|....*...
gi 2319844185 477 VKKNLTELGGQIDVVSVVGKGTTFTVTL 504
Cdd:cd16948 81 VKKLCDKLGHKIDVESEVGEGTTFTITF 108
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
401-488 |
8.36e-17 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 75.96 E-value: 8.36e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 401 KHLYAILKNLIENAIHYTPNGGKIYLCVTKIAGKATFSISDNGPGLTEIEKTRIFERFYRAD--QTRDAEGTGLGLAIVK 478
Cdd:cd16946 3 DRLQQLFVNLLENSLRYTDTGGKLRIRAAQTPQEVRLDVEDSAPGVSDDQLARLFERFYRVEssRNRASGGSGLGLAICH 82
|
90
....*....|
gi 2319844185 479 KNLTELGGQI 488
Cdd:cd16946 83 NIALAHGGTI 92
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
406-504 |
2.43e-16 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 74.67 E-value: 2.43e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 406 ILKNLIENAIHYTPNG--GKIYLCVTKIAGKATFSISDNGPGLTEIEKTRIFERFYRADQTRDAEGTGLGLAIVKKNLTE 483
Cdd:cd16921 4 VLTNLLGNAIKFRRPRrpPRIEVGAEDVGEEWTFYVRDNGIGIDPEYAEKVFGIFQRLHSREEYEGTGVGLAIVRKIIER 83
|
90 100
....*....|....*....|.
gi 2319844185 484 LGGQIDVVSVVGKGTTFTVTL 504
Cdd:cd16921 84 HGGRIWLESEPGEGTTFYFTL 104
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
406-497 |
3.14e-16 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 74.02 E-value: 3.14e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 406 ILKNLIENAIHYtpNGGKIYLCVTKIAGKATFSISDNGPGLTEIEKTRIFERFYRADQTRDAEGTGLGLAIVKKNLTELG 485
Cdd:cd16950 4 VLSNLVDNALRY--GGGWVEVSSDGEGNRTRIQVLDNGPGIAPEEVDELFQPFYRGDNARGTSGTGLGLAIVQRISDAHG 81
|
90
....*....|..
gi 2319844185 486 GQIDVVSVVGKG 497
Cdd:cd16950 82 GSLTLANRAGGG 93
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
203-504 |
4.04e-16 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 81.70 E-value: 4.04e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 203 KGTIRRSNASFQNEFMAT--KNL-----DVFSPYSDVLQFlVNKMLKPTRQEQTFY---------FEK--INAYYTVTVQ 264
Cdd:PRK09959 595 QGNVISHNSAFEHYFTADyyKNAmlpleNSDSPFKDVFSN-AHEVTAETKENRTIYtqvfeidngIEKrcINHWHTLCNL 673
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 265 PI-----------EALERRIMVTMIDVTAYKV--TTRAHNDFIANVSHDLKTPLAAITGFADILvnDSANLPPEKIKGFA 331
Cdd:PRK09959 674 PAsdhavyicgwqDITETRDLIHALEVERNKAinATVAKSQFLATMSHEIRTPISSIMGFLELL--SGSGLSKEQRVEAI 751
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 332 NHIVKETKRLSSLVTDTLEMTR--------QPLHLKKkklnlTALTRDVLENFKLAIQEKSLQVT---TQLDEVTVKSND 400
Cdd:PRK09959 752 SLAYATGQSLLGLIGEILDVDKiesgnyqlQPQWVDI-----PTLVQNTCHSFGAIAASKSIALScssTFPDHYLVKIDP 826
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 401 KHLYAILKNLIENAIHYTPNGG-KIYLCVTKIAGKAT---FSISDNGPGLTEIEKTRIFERFYRADQTRDAEGTGLGLAI 476
Cdd:PRK09959 827 QAFKQVLSNLLSNALKFTTEGAvKITTSLGHIDDNHAvikMTIMDSGSGLSQEEQQQLFKRYSQTSAGRQQTGSGLGLMI 906
|
330 340
....*....|....*....|....*...
gi 2319844185 477 VKKNLTELGGQIDVVSVVGKGTTFTVTL 504
Cdd:PRK09959 907 CKELIKNMQGDLSLESHPGIGTTFTITI 934
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
291-504 |
1.09e-15 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 80.08 E-value: 1.09e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 291 NDFIANVSHDLKTPLAAITGFADILVND--SANLP--PEkikgfANHIVKETKRLSSLVTDTLEMTRQPLHLKKKKLNLT 366
Cdd:PRK10490 665 NALLAALSHDLRTPLTVLFGQAEILTLDlaSEGSPhaRQ-----ASEIRQQVLNTTRLVNNLLDMARIQSGGFNLRKEWL 739
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 367 ALTRDV---LENFKLAIQEKSLQVTTQLDEVTVKSNDKHLYAILKNLIENAIHYTPNGGKIYLCVTKIAGKATFSISDNG 443
Cdd:PRK10490 740 TLEEVVgsaLQMLEPGLSGHPINLSLPEPLTLIHVDGPLFERVLINLLENAVKYAGAQAEIGIDAHVEGERLQLDVWDNG 819
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2319844185 444 PGLTEIEKTRIFERFYRADQTRDAEGTGLGLAIVKKNLTELGGQIDVVSVVGKGTTFTVTL 504
Cdd:PRK10490 820 PGIPPGQEQLIFDKFARGNKESAIPGVGLGLAICRAIVEVHGGTIWAENRPEGGACFRVTL 880
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
265-504 |
1.65e-15 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 78.66 E-value: 1.65e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 265 PIEaLERRI-----MVTMIDvtayKVTTRAHNdFIANVSHDLKTPLAAITGFADILVndSANLPPEKIKGFANHIVKETK 339
Cdd:PRK09835 238 PIE-LEQLVlsfnhMIERIE----DVFTRQSN-FSADIAHEIRTPITNLITQTEIAL--SQSRSQKELEDVLYSNLEELT 309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 340 RLSSLVTDTLEMTRQPLHLKKKKLNLTALTRDVLENFKL--AIQEKSlQVTTQLD--EVTVKSNDKHLYAILKNLIENAI 415
Cdd:PRK09835 310 RMAKMVSDMLFLAQADNNQLIPEKKMLDLADEVGKVFDFfeAWAEER-GVELRFVgdPCQVAGDPLMLRRAISNLLSNAL 388
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 416 HYTPNGGKIYLCVTKIAGKATFSISDNGPGLTEIEKTRIFERFYRAD--QTRDAEGTGLGLAIVKKNLTELGGQIDVVSV 493
Cdd:PRK09835 389 RYTPAGEAITVRCQEVDHQVQLVVENPGTPIAPEHLPRLFDRFYRVDpsRQRKGEGSGIGLAIVKSIVVAHKGTVAVTSD 468
|
250
....*....|.
gi 2319844185 494 VgKGTTFTVTL 504
Cdd:PRK09835 469 A-RGTRFVISL 478
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
403-504 |
2.71e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 71.65 E-value: 2.71e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 403 LYAILKNLIENAIHYTPNGGKIYLCVTKIAGKATFSISDNGPGLTEIEKTRIFERFYRADQTRDAEGTGLGLAIVkKNLT 482
Cdd:cd16923 1 LQRVFSNLLSNAIKYSPENTRIYITSFLTDDVVNIMFKNPSSHPLDFKLEKLFERFYRGDNSRNTEGAGLGLSIA-KAII 79
|
90 100
....*....|....*....|...
gi 2319844185 483 EL-GGQIDvVSVVGKGTTFTVTL 504
Cdd:cd16923 80 ELhGGSAS-AEYDDNHDLFKVRL 101
|
|
| HATPase_YcbM-like |
cd16947 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
393-504 |
2.88e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).
Pssm-ID: 340423 [Multi-domain] Cd Length: 125 Bit Score: 72.16 E-value: 2.88e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 393 EVTVKSNDKHLYA---------ILKNLIENAIHYTPNGGKIYLCVTKIAGKATFSISDNGPGLTEIEKTRIFERFYRADQ 463
Cdd:cd16947 2 QVEINIPDRPIYAnantealqrILKNLISNAIKYGSDGKFLGMTLREDEKHVYIDIWDKGKGISETEKDHVFERLYTLED 81
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 2319844185 464 TRDA--EGTGLGLAIVKKNLTELGGQIDVVSVVGKGTTFTVTL 504
Cdd:cd16947 82 SRNSakQGNGLGLTITKRLAESMGGSIYVNSKPYEKTVFTVTL 124
|
|
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
294-490 |
4.02e-15 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 77.26 E-value: 4.02e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 294 IANVSHDLKTPLAAITGFADILVNDSANLppekikgfANHIVKETKRLSSLVTDTLEMTRQPLHLKKKKLNLTALTRDVL 373
Cdd:PRK09467 233 MAGVSHDLRTPLTRIRLATEMMSEEDGYL--------AESINKDIEECNAIIEQFIDYLRTGQEMPMEMADLNALLGEVI 304
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 374 ENfkLAIQEKSLQVTTQLDEVTVKSNDKHLYAILKNLIENAIHYTpNGG-KIYLCVTKiaGKATFSISDNGPGLTEIEKT 452
Cdd:PRK09467 305 AA--ESGYEREIETALQPGPIEVPMNPIAIKRALANLVVNAARYG-NGWiKVSSGTEG--KRAWFQVEDDGPGIPPEQLK 379
|
170 180 190
....*....|....*....|....*....|....*...
gi 2319844185 453 RIFERFYRADQTRDAEGTGLGLAIVKKNLTELGGQIDV 490
Cdd:PRK09467 380 HLFQPFTRGDSARGSSGTGLGLAIVKRIVDQHNGKVEL 417
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
297-504 |
7.84e-15 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 77.41 E-value: 7.84e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 297 VSHDLKTPLAAITGFADILVNDSANLPP--EKIkgfaNHIVKETKRLSSLVTDTLEMTRqPLHLKKKKLNLTALTRDVLE 374
Cdd:PRK13837 457 IAHNFNNILGAILGYAEMALNKLARHSRaaRYI----DEIISAGARARLIIDQILAFGR-KGERNTKPFDLSELVTEIAP 531
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 375 NFKLAIQEKslqVTTQLDE----VTVKSNDKHLYAILKNLIENAIHYTPNGGKIYLCVTKIAGKAT-------------- 436
Cdd:PRK13837 532 LLRVSLPPG---VELDFDQdqepAVVEGNPAELQQVLMNLCSNAAQAMDGAGRVDISLSRAKLRAPkvlshgvlppgryv 608
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2319844185 437 -FSISDNGPGLTEIEKTRIFERFYradQTRdAEGTGLGLAIVKKNLTELGGQIDVVSVVGKGTTFTVTL 504
Cdd:PRK13837 609 lLRVSDTGAGIDEAVLPHIFEPFF---TTR-AGGTGLGLATVHGIVSAHAGYIDVQSTVGRGTRFDVYL 673
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
406-504 |
3.14e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 68.60 E-value: 3.14e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 406 ILKNLIENAIHYTPNGGKIYLCVTKIAGKATFSISDNGPGLTEIEKTRIFERFYradQTRD-AEGTGLGLAIVKKNLTEL 484
Cdd:cd16943 7 VLLNLLVNAAQAMEGRGRITIRTWAHVDQVLIEVEDTGSGIDPEILGRIFDPFF---TTKPvGEGTGLGLSLSYRIIQKH 83
|
90 100
....*....|....*....|
gi 2319844185 485 GGQIDVVSVVGKGTTFTVTL 504
Cdd:cd16943 84 GGTIRVASVPGGGTRFTIIL 103
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
288-353 |
7.90e-14 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 66.08 E-value: 7.90e-14
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2319844185 288 RAHNDFIANVSHDLKTPLAAITGFADILVNDsaNLPPEKIKGFANHIVKETKRLSSLVTDTLEMTR 353
Cdd:cd00082 2 QAKGEFLANVSHELRTPLTAIRGALELLEEE--LLDDEEQREYLERIREEAERLLRLINDLLDLSR 65
|
|
| HATPase_DpiB-CitA-like |
cd16915 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
403-504 |
1.56e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 DpiB, DcuS, and Bacillus subtilis CitS, DctS, and YufL; This family includes histidine kinase-like ATPase domains of Escherichia coli K-12 DpiB and DcuS, and Bacillus subtilis CitS, DctS and MalK histidine kinases (HKs) all of which are two component transduction systems (TCSs). E. coli K-12 DpiB (also known as CitA) is the histidine kinase (HK) of DpiA-DpiB, a two-component signal transduction system (TCS) required for the expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. E. coli K-12 DcuS (also known as YjdH) is the HK of DcuS-DcuR, a TCS that in the presence of the extracellular C4-dicarboxlates, activates the expression of the genes of anaerobic fumarate respiration and of aerobic C4-dicarboxylate uptake. CitS is the HK of Bacillus subtilis CitS-CitT, a TCS which regulates expression of CitM, the Mg-citrate transporter. Bacillus subtilis DctS forms a tripartite sensor unit (DctS/DctA/DctB) for sensing C4 dicarboxylates. Bacillus subtilis MalK (also known as YfuL) is the HK of MalK-MalR (YufL-YufM) a TCS which regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Proteins having this DpiB-CitA-like HATPase domain generally have sensor domains such as Cache and PAS, and a histidine kinase A (HisKA)-like SpoOB-type, alpha-helical domain.
Pssm-ID: 340392 [Multi-domain] Cd Length: 104 Bit Score: 66.54 E-value: 1.56e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 403 LYAILKNLIENAIHY---TPNGGK-IYLCVTKIAGKATFSISDNGPGLTEIEKTRIFERFYradQTRDAEGTGLGLAIVK 478
Cdd:cd16915 1 LITIVGNLIDNALDAlaaTGAPNKqVEVFLRDEGDDLVIEVRDTGPGIAPELRDKVFERGV---STKGQGERGIGLALVR 77
|
90 100
....*....|....*....|....*.
gi 2319844185 479 KNLTELGGQIDVVSVVGKGTTFTVTL 504
Cdd:cd16915 78 QSVERLGGSITVESEPGGGTTFSIRI 103
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
293-479 |
1.93e-13 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 72.37 E-value: 1.93e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 293 FIANVSHDLKTPLAAI---TGFADILVNDsanlPPEKIKGFANhIVKETKRLSSLVTDTLEMTRQPLHLKKKKLNLTALt 369
Cdd:PRK10337 240 FTSDAAHELRSPLAALkvqTEVAQLSDDD----PQARKKALLQ-LHAGIDRATRLVDQLLTLSRLDSLDNLQDVAEIPL- 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 370 RDVLENFKLAI----QEKSLQVTTQLDEVTVKSNDKHLYAIL--KNLIENAIHYTPNGGKIYLCVTKiagkATFSISDNG 443
Cdd:PRK10337 314 EDLLQSAVMDIyhtaQQAGIDVRLTLNAHPVIRTGQPLLLSLlvRNLLDNAIRYSPQGSVVDVTLNA----RNFTVRDNG 389
|
170 180 190
....*....|....*....|....*....|....*.
gi 2319844185 444 PGLTEIEKTRIFERFYRAdQTRDAEGTGLGLAIVKK 479
Cdd:PRK10337 390 PGVTPEALARIGERFYRP-PGQEATGSGLGLSIVRR 424
|
|
| PRK11107 |
PRK11107 |
hybrid sensory histidine kinase BarA; Provisional |
406-504 |
5.18e-13 |
|
hybrid sensory histidine kinase BarA; Provisional
Pssm-ID: 236848 [Multi-domain] Cd Length: 919 Bit Score: 71.80 E-value: 5.18e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 406 ILKNLIENAIHYTPNGgKIYLCVTKIAGKAT-----FSISDNGPGLTEIEKTRIFERFYRADQ--TRDAEGTGLGLAIVK 478
Cdd:PRK11107 412 IITNLVGNAIKFTESG-NIDILVELRALSNTkvqleVQIRDTGIGISERQQSQLFQAFRQADAsiSRRHGGTGLGLVITQ 490
|
90 100
....*....|....*....|....*.
gi 2319844185 479 KNLTELGGQIDVVSVVGKGTTFTVTL 504
Cdd:PRK11107 491 KLVNEMGGDISFHSQPNRGSTFWFHL 516
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
407-500 |
1.94e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 63.63 E-value: 1.94e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 407 LKNLIENAIHYTPNGGKIYLCVTKIAGKATFSISDNGPGLTEIEKTRIFERFY---RADQTRdaEGTGLGLAIVKKNLTE 483
Cdd:cd16945 9 INNLLDNAIDFSPEGGLIALQLEADTEGIELLVFDEGSGIPDYALNRVFERFYslpRPHSGQ--KSTGLGLAFVQEVAQL 86
|
90
....*....|....*..
gi 2319844185 484 LGGQIDVVSVVGKGTTF 500
Cdd:cd16945 87 HGGRITLRNRPDGVLAF 103
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
406-504 |
5.02e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 62.09 E-value: 5.02e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 406 ILKNLIENA---IHYTPNGgKIYLCVTKIAGKATFSISDNGPGLTEIEKTRIFERFYradQTRD-AEGTGLGLAIVKKNL 481
Cdd:cd16976 4 VLMNLLQNAldaMGKVENP-RIRIAARRLGGRLVLVVRDNGPGIAEEHLSRVFDPFF---TTKPvGKGTGLGLSISYGIV 79
|
90 100
....*....|....*....|...
gi 2319844185 482 TELGGQIDVVSVVGKGTTFTVTL 504
Cdd:cd16976 80 EEHGGRLSVANEEGAGARFTFDL 102
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
406-504 |
6.20e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 62.03 E-value: 6.20e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 406 ILKNLIENAI----HYTPNGGKIYLCVTkIAGKA--TFSISDNGPGLTEIEKTRIFERFYradqTRDAEGTGLGLAIVKK 479
Cdd:cd16920 4 VLINLVRNGIeamsEGGCERRELTIRTS-PADDRavTISVKDTGPGIAEEVAGQLFDPFY----TTKSEGLGMGLSICRS 78
|
90 100
....*....|....*....|....*
gi 2319844185 480 NLTELGGQIDVVSVVGKGTTFTVTL 504
Cdd:cd16920 79 IIEAHGGRLSVESPAGGGATFQFTL 103
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
289-353 |
7.85e-12 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 60.66 E-value: 7.85e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2319844185 289 AHNDFIANVSHDLKTPLAAITGFADILVNDSANLPPEKikgFANHIVKETKRLSSLVTDTLEMTR 353
Cdd:smart00388 1 AKREFLANLSHELRTPLTAIRGYLELLLDTELSEEQRE---YLETILREAERLLRLINDLLDLSR 62
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
289-353 |
7.92e-12 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 60.30 E-value: 7.92e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2319844185 289 AHNDFIANVSHDLKTPLAAITGFADILvndSANLPPEKIKGFANHIVKETKRLSSLVTDTLEMTR 353
Cdd:pfam00512 1 AKSEFLANLSHELRTPLTAIRGYLELL---RDEKLDEEQREYLETILRSAERLLRLINDLLDLSR 62
|
|
| PRK10841 |
PRK10841 |
two-component system sensor histidine kinase RcsC; |
293-502 |
1.08e-11 |
|
two-component system sensor histidine kinase RcsC;
Pssm-ID: 182772 [Multi-domain] Cd Length: 924 Bit Score: 67.31 E-value: 1.08e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 293 FIANVSHDLKTPLAAITGFADILvnDSANLPPEkikgfANHIVKETKRLSSL----VTDTLEMTRqplhlkkkklnltal 368
Cdd:PRK10841 450 FLATVSHELRTPLYGIIGNLDLL--QTKELPKG-----VDRLVTAMNNSSSLllkiISDILDFSK--------------- 507
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 369 trdvLENFKLAIQEK----------------SLQVTTQLD---------EVTVKSNDKHLYAILKNLIENAIHYTPNGGk 423
Cdd:PRK10841 508 ----IESEQLKIEPRefsprevinhitanylPLVVKKRLGlycfiepdvPVALNGDPMRLQQVISNLLSNAIKFTDTGC- 582
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 424 IYLCVTKIAGKATFSISDNGPGLTEIEKTRIFERFYRADQ--TRDAEGTGLGLAIVKKNLTELGGQIDVVSVVGKGTTFT 501
Cdd:PRK10841 583 IVLHVRVDGDYLSFRVRDTGVGIPAKEVVRLFDPFFQVGTgvQRNFQGTGLGLAICEKLINMMDGDISVDSEPGMGSQFT 662
|
.
gi 2319844185 502 V 502
Cdd:PRK10841 663 I 663
|
|
| HATPase_PhoQ-like |
cd16954 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
381-504 |
1.11e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.
Pssm-ID: 340430 [Multi-domain] Cd Length: 135 Bit Score: 62.26 E-value: 1.11e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 381 QEKSLQVTTQLDEVTVKSNDKH-LYAILKNLIENAIHYTpnGGKIYLCVTKIAGKATFSISDNGPGLTEIEKTRIFERFY 459
Cdd:cd16954 15 QRKGVSISLDISPELRFPGERNdLMELLGNLLDNACKWC--LEFVEVTARQTDGGLHLIVDDDGPGVPESQRSKIFQRGQ 92
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 2319844185 460 RADQTRdaEGTGLGLAIVKKNLTELGGQIDVVSVVGKGTTFTVTL 504
Cdd:cd16954 93 RLDEQR--PGQGLGLAIAKEIVEQYGGELSLSDSPLGGARFEVVF 135
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
407-504 |
6.83e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 58.98 E-value: 6.83e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 407 LKNLIENAIHYTPNGGKIYLCVTkiAGKATFSISDNGPGLTEIEKTRIFERFYRADQTRDAE--GTGLGLAIVKKNLTEL 484
Cdd:cd16939 5 LDNLLRNALRYAHRTVRIALLVS--GGRLTLIVEDDGPGIPAAARERVFEPFVRLDPSRDRAtgGFGLGLAIVHRVALWH 82
|
90 100
....*....|....*....|
gi 2319844185 485 GGQIDVVSVVGKGTTFTVTL 504
Cdd:cd16939 83 GGHVECDDSELGGACFRLTW 102
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
288-504 |
6.99e-11 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 64.93 E-value: 6.99e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 288 RAHNDFIANVSHDLKTPLAAITGFADILVNDSANlppEKIKGFANHIVKETKRLSSLVTDTLEMTRQPLHLKKKKLNLTA 367
Cdd:PRK11466 442 QAKSAFLAAMSHEIRTPLYGILGTAQLLADNPAL---NAQRDDLRAITDSGESLLTILNDILDYSAIEAGGKNVSVSDEP 518
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 368 LT-RDVLEN-FKLA---IQEKSLQVTTQLDEV---TVKSNDKHLYAILKNLIENAIHYTPNGGKIYLCVTKiaGKATF-S 438
Cdd:PRK11466 519 FEpRPLLEStLQLMsgrVKGRPIRLATDIADDlptALMGDPRRIRQVITNLLSNALRFTDEGSIVLRSRTD--GEQWLvE 596
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2319844185 439 ISDNGPGLTEIEKTRIFERFYRADQTRDaeGTGLGLAIVKKNLTELGGQIDVVSVVGKGTTFTVTL 504
Cdd:PRK11466 597 VEDSGCGIDPAKLAEIFQPFVQVSGKRG--GTGLGLTISSRLAQAMGGELSATSTPEVGSCFCLRL 660
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
294-501 |
7.28e-11 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 64.24 E-value: 7.28e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 294 IANVSHDLKTPLAAITGFADILVNDSAnlpPEKIKgfanhIVKETKRLSSLVTDTL---EMTRQPLHLKKKKLNLTALTR 370
Cdd:PRK10604 216 IDGIAHELRTPLVRLRYRLEMSDNLSA---AESQA-----LNRDIGQLEALIEELLtyaRLDRPQNELHLSEPDLPAWLS 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 371 DVLENFKLAIQEKSLQVTTQLDEVTVKSNDKHLYAILKNLIENAIHYtpNGGKIYLCVTKIAGKATFSISDNGPGLTEIE 450
Cdd:PRK10604 288 THLADIQAVTPEKTVRLDTPHQGDYGALDMRLMERVLDNLLNNALRY--AHSRVRVSLLLDGNQACLIVEDDGPGIPPEE 365
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 2319844185 451 KTRIFERFYRADQTRDAE--GTGLGLAIVKKNLTELGGQIDVVSVVGKGTTFT 501
Cdd:PRK10604 366 RERVFEPFVRLDPSRDRAtgGCGLGLAIVHSIALAMGGSVNCDESELGGARFS 418
|
|
| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
293-477 |
7.84e-11 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 63.45 E-value: 7.84e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 293 FIANVSHDLKTPLAAITGFADILvndsanlppEKikgfaNHIVKET---KRLSSL---VTDTLEMTRQPLHLKKKKLNLT 366
Cdd:PRK10755 140 FTADVAHELRTPLAGIRLHLELL---------EK-----QHHIDVApliARLDQMmhtVEQLLQLARAGQSFSSGHYQTV 205
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 367 ALTRDVL----ENFK--LAIQEKSLQVTTQLDEVTVKSNDKHLYAILKNLIENAIHYTPNGGKIYLCVTKIAGKATFSIS 440
Cdd:PRK10755 206 KLLEDVIlpsqDELSemLEQRQQTLLLPESAADITVQGDATLLRLLLRNLVENAHRYSPEGSTITIKLSQEDGGAVLAVE 285
|
170 180 190
....*....|....*....|....*....|....*..
gi 2319844185 441 DNGPGLTEIEKTRIFERFYRADQTRDaeGTGLGLAIV 477
Cdd:PRK10755 286 DEGPGIDESKCGELSKAFVRMDSRYG--GIGLGLSIV 320
|
|
| PRK11086 |
PRK11086 |
sensory histidine kinase DcuS; Provisional |
375-504 |
8.65e-11 |
|
sensory histidine kinase DcuS; Provisional
Pssm-ID: 236839 [Multi-domain] Cd Length: 542 Bit Score: 64.16 E-value: 8.65e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 375 NFKLAIQEKSL-------QVTTQLdeVTVksndkhlyaiLKNLIENAIHYTPN--GGKIYLCVTKIAGKATFSISDNGPG 445
Cdd:PRK11086 411 GITLIISEDSQlpdsgdeDQVHEL--ITI----------LGNLIENALEAVGGeeGGEISVSLHYRNGWLHCEVSDDGPG 478
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 2319844185 446 LTEIEKTRIFERFYradqTRDAEGTGLGLAIVKKNLTELGGQIDVVSVVGKGTTFTVTL 504
Cdd:PRK11086 479 IAPDEIDAIFDKGY----STKGSNRGVGLYLVKQSVENLGGSIAVESEPGVGTQFFVQI 533
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
403-504 |
1.87e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 57.97 E-value: 1.87e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 403 LYAILKNLIENAIHYTP-NGGKIYLCVTKIAGKATFSISDNGPGLTEIEKTRIFERFYRADQTRDAEGT--GLGLAIVKK 479
Cdd:cd16953 1 LGQVLRNLIGNAISFSPpDTGRITVSAMPTGKMVTISVEDEGPGIPQEKLESIFDRFYTERPANEAFGQhsGLGLSISRQ 80
|
90 100
....*....|....*....|....*....
gi 2319844185 480 NLTELGGQIDVVSV----VGKGTTFTVTL 504
Cdd:cd16953 81 IIEAHGGISVAENHnqpgQVIGARFTVQL 109
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
403-488 |
8.69e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 55.93 E-value: 8.69e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 403 LYAILKNLIENAIHYTPNGGKIYLCVTKIAGKATFSISDNGPGLTEIEKTRIFERFYRADQTRDAEG-TGLGLAIVKKNL 481
Cdd:cd16975 5 LSRALINIISNACQYAPEGGTVSISIYDEEEYLYFEIWDNGHGFSEQDLKKALELFYRDDTSRRSGGhYGMGLYIAKNLV 84
|
....*..
gi 2319844185 482 TELGGQI 488
Cdd:cd16975 85 EKHGGSL 91
|
|
| HATPase_CckA-like |
cd16919 |
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar ... |
405-504 |
1.08e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar to Brucella abortus 2308 CckA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) similar to Brucella abortus 2308 CckA, which is a component of an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival; phosphoryl transfer initiates from the sensor kinase CckA and proceeds via the ChpT phosphotransferase to two regulatory substrates: the DNA-binding response regulator CtrA and the phospho-receiver protein CpdR. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), a REC signal receiver domain, and some contain PAS or PAS and GAF sensor domain(s).
Pssm-ID: 340396 [Multi-domain] Cd Length: 116 Bit Score: 55.85 E-value: 1.08e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 405 AILkNLIENAIHYTPNGGKIYL---CVTKIAGKAT------------FSISDNGPGLTEIEKTRIFERFYRADQTrdAEG 469
Cdd:cd16919 4 AIL-NLAVNARDAMPEGGRLTIetsNQRVDADYALnyrdlipgnyvcLEVSDTGSGMPAEVLRRAFEPFFTTKEV--GKG 80
|
90 100 110
....*....|....*....|....*....|....*
gi 2319844185 470 TGLGLAIVKKNLTELGGQIDVVSVVGKGTTFTVTL 504
Cdd:cd16919 81 TGLGLSMVYGFVKQSGGHLRIYSEPGVGTTVRIYL 115
|
|
| CheA |
COG0643 |
Chemotaxis protein histidine kinase CheA [Signal transduction mechanisms]; |
461-504 |
6.12e-09 |
|
Chemotaxis protein histidine kinase CheA [Signal transduction mechanisms];
Pssm-ID: 440408 [Multi-domain] Cd Length: 563 Bit Score: 58.27 E-value: 6.12e-09
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 2319844185 461 ADQTRDAEGTGLGLAIVKKNLTELGGQIDVVSVVGKGTTFTVTL 504
Cdd:COG0643 373 AEEVTDLSGRGVGMDVVKTNIEALGGTIEIESEPGKGTTFTLRL 416
|
|
| glnL |
PRK11073 |
nitrogen regulation protein NR(II); |
244-504 |
5.01e-08 |
|
nitrogen regulation protein NR(II);
Pssm-ID: 182947 [Multi-domain] Cd Length: 348 Bit Score: 54.70 E-value: 5.01e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 244 TRQEQTFYFEKINAYYTVTVQPIEalERRIMVTMIDVTAYKVTTR---------AHNDFIANVSHDLKTPLAAITGFADI 314
Cdd:PRK11073 77 TDNEVTLVIDGRSHILSLTAQRLP--EGMILLEMAPMDNQRRLSQeqlqhaqqvAARDLVRGLAHEIKNPLGGLRGAAQL 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 315 LvndSANLPPEKIKGFANHIVKETKRLSSLVtDTLEMTRQPLHLKKKKLNLtaltrdVLEN-FKLAIQEKSLQVTTQLD- 392
Cdd:PRK11073 155 L---SKALPDPALTEYTKVIIEQADRLRNLV-DRLLGPQRPGTHVTESIHK------VAERvVQLVSLELPDNVRLIRDy 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 393 -----EVTVKSNdkHLYAILKNLIENAIH-YTPNGGKIYLcVTKIAGKATF-----------SISDNGPGL-TEIEKTRi 454
Cdd:PRK11073 225 dpslpELAHDPD--QIEQVLLNIVRNALQaLGPEGGTITL-RTRTAFQLTLhgeryrlaariDIEDNGPGIpPHLQDTL- 300
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 2319844185 455 ferFYRADQTRDAeGTGLGLAIVKKNLTELGGQIDVVSVVGKgTTFTVTL 504
Cdd:PRK11073 301 ---FYPMVSGREG-GTGLGLSIARNLIDQHSGKIEFTSWPGH-TEFSVYL 345
|
|
| HATPase_CheA-like |
cd16916 |
Histidine kinase-like ATPase domain of the chemotaxis protein histidine kinase CheA, and some ... |
446-504 |
5.05e-08 |
|
Histidine kinase-like ATPase domain of the chemotaxis protein histidine kinase CheA, and some hybrid sensor histidine kinases; This family includes the cytoplasmic histidine kinase (HK) CheA, a transmembrane receptor which, together with cytoplasmic adaptor protein (CheW), forms the lattice at the core of the chemosensory array that controls the cellular chemotaxis of motile bacteria and archaea. CheA forms a two-component signal transduction system (TCS) with the response regulator CheY. Proteins having this CheA-like HATPase domain generally also have a histidine-phosphotransfer domain, a histidine kinase homodimeric domain, and a regulatory domain; some are hybrid sensor histidine kinases as they contain a REC signal receiver domain.
Pssm-ID: 340393 [Multi-domain] Cd Length: 178 Bit Score: 52.58 E-value: 5.05e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2319844185 446 LTEIEKTR-IFER-FYRADQTRDAEGTGLGLAIVKKNLTELGGQIDVVSVVGKGTTFTVTL 504
Cdd:cd16916 117 LSDDEVLNlIFAPgFSTAEQVTDVSGRGVGMDVVKRSIESLGGTIEVESEPGQGTTFTIRL 177
|
|
| PRK10547 |
PRK10547 |
chemotaxis protein CheA; Provisional |
409-504 |
7.01e-08 |
|
chemotaxis protein CheA; Provisional
Pssm-ID: 236712 [Multi-domain] Cd Length: 670 Bit Score: 55.12 E-value: 7.01e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 409 NLIENAIHytpNGGKIYLCVT---------KIAGKAT---FSISDNgpgLTEIE-KTRIFER-FYRADQTRDAEGTGLGL 474
Cdd:PRK10547 418 NLILSAEH---QGGNICIEVTddgaglnreRILAKAAsqgLAVSEN---MSDEEvGMLIFAPgFSTAEQVTDVSGRGVGM 491
|
90 100 110
....*....|....*....|....*....|
gi 2319844185 475 AIVKKNLTELGGQIDVVSVVGKGTTFTVTL 504
Cdd:PRK10547 492 DVVKRNIQEMGGHVEIQSKQGKGTTIRILL 521
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
406-504 |
8.40e-08 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 54.64 E-value: 8.40e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 406 ILKNLIENAIHY----TPNGGKIYLCVTKIAGKATFSISDNGPGLTEIEKTRIFERFyradqTRDAEGTGLGLAIVKKNL 481
Cdd:COG2972 340 ILQPLVENAIEHgiepKEGGGTIRISIRKEGDRLVITVEDNGVGMPEEKLEKLLEEL-----SSKGEGRGIGLRNVRERL 414
|
90 100
....*....|....*....|....*.
gi 2319844185 482 TEL---GGQIDVVSVVGKGTTFTVTL 504
Cdd:COG2972 415 KLYygeEYGLEIESEPGEGTTVTIRI 440
|
|
| COG3920 |
COG3920 |
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction ... |
367-504 |
1.60e-07 |
|
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms];
Pssm-ID: 443125 [Multi-domain] Cd Length: 495 Bit Score: 53.76 E-value: 1.60e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 367 ALTRDVLENFKLAIQEKSLQVTTQLDEVTVKSNDkhlyA-----ILKNLIENAIHY---TPNGGKIYLCVTKIAGKATFS 438
Cdd:COG3920 363 DYLRELLEPLRDSYGGRGIRIELDGPDVELPADA----AvplglILNELVTNALKHaflSGEGGRIRVSWRREDGRLRLT 438
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2319844185 439 ISDNGPGLTEiektriferfyradQTRDAEGTGLGLAIVKKNLTELGGQIDVVSvvGKGTTFTVTL 504
Cdd:COG3920 439 VSDNGVGLPE--------------DVDPPARKGLGLRLIRALVRQLGGTLELDR--PEGTRVRITF 488
|
|
| HATPase_Glnl-NtrB-like |
cd16918 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
406-504 |
1.80e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli GlnL (synonyms NtrB and NRII); This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs), similar to Escherichia coli GlnL/NtrB/NRII HK of the two-component regulatory system (TCS) GlnL/GlnG (NtrB-NtrC, or NRII-NRI), which regulates the transcription of genes encoding metabolic enzymes and permeases in response to carbon and nitrogen status in E. coli and related bacteria. Also included in this family are Rhodobacter capsulatus NtrB, Azospirillum brasilense NtrB, Vibrio alginolyticus NtrB, Rhizobium leguminosarum biovar phaseoli NtrB, and Herbaspirillum seropedicae NtrB. Escherichia coli GlnL/NtrB/NRII is both a kinase and a phosphatase, catalyzing the phosphorylation and dephosphorylation of GlnG/NtrC/NRI. The kinase and phosphatase activities of GlnL/NtrB/NRII are regulated by the PII signal transduction protein, which on binding to GlnL/NtrB/NRII, inhibits the kinase activity of GlnL/NtrB/NRII and activates the GlnL/NtrB/NRII phosphatase activity. Proteins having this HATPase domain also have a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also contain PAS sensor domain(s).
Pssm-ID: 340395 [Multi-domain] Cd Length: 109 Bit Score: 49.32 E-value: 1.80e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 406 ILKNLIENAIHYTPNGGKIYLCVTKIAGKATF-----------SISDNGPGLTEIEKTRIFERFYradqTRDAEGTGLGL 474
Cdd:cd16918 4 VFLNLVRNAAQALAGSGGEIILRTRTQRQVTLghprhrlalrvSVIDNGPGIPPDLQDTIFYPMV----SGRENGTGLGL 79
|
90 100 110
....*....|....*....|....*....|
gi 2319844185 475 AIVKKNLTELGGQIDVVSVVGKgTTFTVTL 504
Cdd:cd16918 80 AIAQNIVSQHGGVIECDSQPGH-TVFSVSL 108
|
|
| LytS |
COG3275 |
Sensor histidine kinase, LytS/YehU family [Signal transduction mechanisms]; |
410-504 |
1.92e-07 |
|
Sensor histidine kinase, LytS/YehU family [Signal transduction mechanisms];
Pssm-ID: 442506 [Multi-domain] Cd Length: 352 Bit Score: 52.95 E-value: 1.92e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 410 LIENAIHY----TPNGGKIYLCVTKIAGKATFSISDNGPGLteiektriferfyraDQTRDAEGTGLGLAIVKKNLTELG 485
Cdd:COG3275 261 LVENAIKHgissKEGGGTISISIEVEGDRLVIEVENNGVGI---------------QPKKKKKGSGIGLKNVRERLELLY 325
|
90 100
....*....|....*....|..
gi 2319844185 486 G---QIDVVSVVGKGTTFTVTL 504
Cdd:COG3275 326 GdkySLEIESTDGGGTKVTLKI 347
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
403-504 |
8.66e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 47.53 E-value: 8.66e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 403 LYAILKNLIEnAIHYTPNG-GKIYLCV-TKIAGKATFSISDNGPGLTEIEKTRIFERFYradqTRDAEGTGLGLAIVKKN 480
Cdd:cd16944 9 LTNILKNAAE-AIEGRPSDvGEVRIRVeADQDGRIVLIVCDNGKGFPREMRHRATEPYV----TTRPKGTGLGLAIVKKI 83
|
90 100
....*....|....*....|....
gi 2319844185 481 LTELGGQIDVVSVVGKGTTFTVTL 504
Cdd:cd16944 84 MEEHGGRISLSNREAGGACIRIIL 107
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
378-497 |
1.18e-06 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 51.23 E-value: 1.18e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 378 LAIQEKSLQVTTQL-DEVTVKSNDKHLYAILKNLIENAIHYTPNGGKIYLCVTKIAGKATFSISDNGPGLTEIEKtrIFE 456
Cdd:COG4192 518 VESRAKPQQITLHIpDDLMVQGDQVLLEQVLVNLLVNALDAVATQPQISVDLLSNAENLRVAISDNGNGWPLVDK--LFT 595
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 2319844185 457 RFYradqTRDAEGTGLGLAIVKKNLTELGGQIDVVSVVGKG 497
Cdd:COG4192 596 PFT----TTKEVGLGLGLSICRSIMQQFGGDLYLASTLERG 632
|
|
| ComP |
COG4585 |
Signal transduction histidine kinase ComP [Signal transduction mechanisms]; |
402-504 |
2.61e-06 |
|
Signal transduction histidine kinase ComP [Signal transduction mechanisms];
Pssm-ID: 443642 [Multi-domain] Cd Length: 252 Bit Score: 48.85 E-value: 2.61e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 402 HLYAILKNLIENAIHYTPnGGKIYLCVTKIAGKATFSISDNGPGLTeiektriferfyradqTRDAEGTGLGLAIVKKNL 481
Cdd:COG4585 162 ALYRIVQEALTNALKHAG-ATRVTVTLEVDDGELTLTVRDDGVGFD----------------PEAAPGGGLGLRGMRERA 224
|
90 100
....*....|....*....|...
gi 2319844185 482 TELGGQIDVVSVVGKGTTFTVTL 504
Cdd:COG4585 225 EALGGTLTIGSAPGGGTRVRATL 247
|
|
| HATPase_UhpB-NarQ-NarX-like |
cd16917 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
403-504 |
4.28e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli UhpB, NarQ and NarX, and Bacillus subtilis YdfH, YhcY and YfiJ; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli UhpB, a HK of the UhpB-UhpA TCS, NarQ and NarX, HKs of the NarQ-NarP and NarX-NarL TCSs, respectively, and Bacillus YdfH, YhcY and YfiJ HKs, of the YdfH-YdfI, YhcY-YhcZ and YfiJ-YfiK TCSs, respectively. In addition, it includes Bacillus YxjM, ComP, LiaS and DesK, HKs of the YxjM-YxjML, ComP-ComA, LiaS-LiaR, DesR-DesK TCSs, respectively. Proteins having this HATPase domain have a histidine kinase dimerization and phosphoacceptor domain; some have accessory domains such as GAF, HAMP, PAS and MASE sensor domains.
Pssm-ID: 340394 [Multi-domain] Cd Length: 87 Bit Score: 42.16 E-value: 4.28e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 403 LYAILKNLIENAIHYTPnGGKIYLCVTKIAGKATFSISDNGPGLTEIEKTRiferfyradqtrdaeGTGLGLAIVKKNLT 482
Cdd:cd16917 1 LYRIVQEALTNALKHAG-ASRVRVTLSYTADELTLTVVDDGVGFDGPAPPG---------------GGGFGLLGMRERAE 64
|
90 100
....*....|....*....|..
gi 2319844185 483 ELGGQIDVVSVVGKGTTFTVTL 504
Cdd:cd16917 65 LLGGTLTIGSRPGGGTRVTARL 86
|
|
| PRK13557 |
PRK13557 |
histidine kinase; Provisional |
435-499 |
4.30e-04 |
|
histidine kinase; Provisional
Pssm-ID: 237425 [Multi-domain] Cd Length: 540 Bit Score: 42.74 E-value: 4.30e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2319844185 435 ATFSISDNGPGLTEIEKTRIFERFYradQTRD-AEGTGLGLAIVKKNLTELGGQIDVVSVVGKGTT 499
Cdd:PRK13557 325 VSIAVTDTGSGMPPEILARVMDPFF---TTKEeGKGTGLGLSMVYGFAKQSGGAVRIYSEVGEGTT 387
|
|
| HATPase_YpdA-YehU-LytS-like |
cd16924 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
405-504 |
4.42e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli YpdA, YehU, Bacillus subtilis LytS, and some hybrid sensor histidine kinases; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis LytS, a HK of the two-component system (TCS) LytS-LytR needed for growth on pyruvate, and Staphylococcus aureus LytS-LytR TCS involved in the adaptation of S. aureus to cationic antimicrobial peptides. It also includes the HATPase domains of Escherichia coli YpdA and YehU, HKs of YpdA-YpdB and YehU-YehTCSs, which are involved together in a nutrient sensing regulatory network. Proteins having this HATPase domain also contain a histidine kinase domain (His-kinase), some having accessory sensor domain(s) such as Cache, HAMP or GAF; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340401 [Multi-domain] Cd Length: 103 Bit Score: 39.74 E-value: 4.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 405 AILKNLIENAI-HYTP---NGGKIYLCVTKIAGKATFSISDNGPGLTEIEKTRIferfyradQTRDAEGTGLGLAIVKKN 480
Cdd:cd16924 4 FTLQPLVENAIqHGLSpltDKGVVTISALKEDNHVMIEVEDNGRGIDPKVLNIL--------GKKPKEGNGIGLYNVHQR 75
|
90 100
....*....|....*....|....*..
gi 2319844185 481 LTELGGQ---IDVVSVVGKGTTFTVTL 504
Cdd:cd16924 76 LILLFGEdygIHIASEPDKGTRITFTI 102
|
|
| RsbW |
COG2172 |
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; |
410-504 |
5.84e-04 |
|
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms];
Pssm-ID: 441775 [Multi-domain] Cd Length: 127 Bit Score: 39.90 E-value: 5.84e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 410 LIENAIHYTPNG---GKIYLCVTKIAGKATFSISDNGPGlteiektriFERFYRADQTRDAEGTGLGLAIVKKNLTELgg 486
Cdd:COG2172 42 AVTNAVRHAYGGdpdGPVEVELELDPDGLEIEVRDEGPG---------FDPEDLPDPYSTLAEGGRGLFLIRRLMDEV-- 110
|
90
....*....|....*...
gi 2319844185 487 qiDVVSVVGkGTTFTVTL 504
Cdd:COG2172 111 --EYESDPG-GTTVRLVK 125
|
|
| PRK10815 |
PRK10815 |
two-component system sensor histidine kinase PhoQ; |
406-488 |
1.96e-03 |
|
two-component system sensor histidine kinase PhoQ;
Pssm-ID: 182754 [Multi-domain] Cd Length: 485 Bit Score: 40.77 E-value: 1.96e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 406 ILKNLIENAIHYTPNGGKIYLCVTKiaGKATFSISDNGPGLTEIEKTRIFERFYRADQTRdaEGTGLGLAIVKKNLTELG 485
Cdd:PRK10815 382 VMGNVLDNACKYCLEFVEISARQTD--EHLHIVVEDDGPGIPESKRELIFDRGQRADTLR--PGQGLGLSVAREITEQYE 457
|
...
gi 2319844185 486 GQI 488
Cdd:PRK10815 458 GKI 460
|
|
| PRK14868 |
PRK14868 |
DNA topoisomerase VI subunit B; Provisional |
398-482 |
3.35e-03 |
|
DNA topoisomerase VI subunit B; Provisional
Pssm-ID: 237842 [Multi-domain] Cd Length: 795 Bit Score: 40.17 E-value: 3.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 398 SNDKHLYAILKNLIENAIHYTPNGG---KIYLCVTKIAGKATFSISDNGPGLTEIEKTRIF------ERFYRADQTRDAE 468
Cdd:PRK14868 42 SGARGLVTAVKEAVDNALDATEEAGilpDIYVEIEEVGDYYRLVVEDNGPGITKEQIPKVFgkllygSRFHAREQSRGQQ 121
|
90
....*....|....
gi 2319844185 469 GTGLGLAIVKKNLT 482
Cdd:PRK14868 122 GIGISAAVLYSQLT 135
|
|
| HATPase_YehU-like |
cd16956 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
407-504 |
4.16e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli YehU; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) including Escherichia coli YehU, a HK of the two-component system (TCS) YehU-YehT which is involved in a nutrient sensing regulatory network. Proteins having this HATPase domain also contain a histidine kinase domain (His-kinase); some have a GAF sensor domain while some have a cupin domain.
Pssm-ID: 340432 [Multi-domain] Cd Length: 101 Bit Score: 36.65 E-value: 4.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 407 LKNLIENAI-HYT---PNGGKIYLCVTKIAGKATFSISDNGPGLTEIEKTRIFERfyradqtrdaEGTGLGLAIVKKNLT 482
Cdd:cd16956 6 LQPIVENAVkHGLsglLDGGRVEITARLDGQHLLLEVEDNGGGMDPDTLARILIR----------SSNGLGLNLVDKRLR 75
|
90 100
....*....|....*....|....*
gi 2319844185 483 ELGGQ---IDVVSVVGKGTTFTVTL 504
Cdd:cd16956 76 QAFGNdygLDIECAPGEGTRITIRL 100
|
|
| HATPase_TopVIB-like |
cd16933 |
Histidine kinase-like ATPase domain of type IIB topoisomerase, Topo VI, subunit B; This family ... |
401-482 |
7.70e-03 |
|
Histidine kinase-like ATPase domain of type IIB topoisomerase, Topo VI, subunit B; This family includes the histidine kinase-like ATPase (HATPase) domain of the B subunit of topoisomerase VI (Topo VIB). Topo VI is a heterotetrameric complex composed of two TopVIA and two TopVIB subunits and is categorized as a type II B DNA topoisomerase. It is found in archaea and also in plants. Type II enzymes cleave both strands of a DNA duplex and pass a second duplex through the resulting break in an ATP-dependent mechanism. DNA cleavage by Topo VI generates two-nucleotide 5'-protruding ends.
Pssm-ID: 340410 [Multi-domain] Cd Length: 203 Bit Score: 37.71 E-value: 7.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319844185 401 KHLYAILKNLIENAIHYTPNGG---KIYLCVTKI-AGKATFSISDNGPGLTEIEKTRIFERF-----YRADQTRDAEGTG 471
Cdd:cd16933 18 RSLYTTVRELVENSLDATEEAGilpDIKVEIEEIgKDHYKVIVEDNGPGIPEEQIPKVFGKVlygskYHNKQSRGQQGLG 97
|
90
....*....|.
gi 2319844185 472 LGLAIVKKNLT 482
Cdd:cd16933 98 ISAAVLYSQMT 108
|
|
| |
