|
Name |
Accession |
Description |
Interval |
E-value |
| SpoU |
COG0566 |
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA ... |
168-429 |
5.83e-77 |
|
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA G18 (ribose-2'-O)-methylase SpoU is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440332 [Multi-domain] Cd Length: 265 Bit Score: 240.10 E-value: 5.83e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 168 RDIPDDTSAEPASESADNLVYGRNPVREYLNCGQSANVLYTAVGV-GGLSDIIALARDRGIPVKEVSRDKLDRICGFngm 246
Cdd:COG0566 10 KDLRKLRDKKYREEEGLFLAEGRHAVEEALKAGREIEELLVTEGAlDRLAELLALAKAAGIPVYEVSREVLDKLSGT--- 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 247 sggGRNGGVVLEVASAQYVEISDILEiarSRNEPPFIIISDGITDPHNLGAVIRTALSAGAHGVVIPKRGGVSVTPavaa 326
Cdd:COG0566 87 ---ETHQGVLAVVRPPEYADLEDLLA---EAGEPPLLLVLDGVQDPGNLGAILRSAAAFGVDGVILPKRRADPYNP---- 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 327 asagatA----------YLAVARVTNISETIELLKNEGVFVYGASAEGE-NYRRASLSGAVALVIGNEGDGLRRLTRERC 395
Cdd:COG0566 157 ------KvvrasagalfHVPVARVTNLADALEELKEAGFWVVGTDLDGEaSLYEVDLPGPVALVLGNEGKGLSRLVLEAC 230
|
250 260 270
....*....|....*....|....*....|....
gi 2319736509 396 DALIGIDMLGAVGSLNASVSAGVLMYEVVRARAG 429
Cdd:COG0566 231 DELVRIPMAGGVESLNVAVAAAILLYEAARQRRA 264
|
|
| rRNA_methyl_3 |
TIGR00186 |
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases ... |
186-427 |
6.04e-63 |
|
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129290 [Multi-domain] Cd Length: 237 Bit Score: 202.96 E-value: 6.04e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 186 LVYGRNPVREYLNCGQSANVLYTAVGvGGLSDIIALARDRGIPVKEVSRDKLDRIcgfngmSGGGRNGGVVLEVASAQYV 265
Cdd:TIGR00186 3 YLYGKNAVLEALLNQQRVFILKGLES-KRLKKLIQLAKKQGINIQLVDRQKLDQL------TKGGNHQGIAAKVKPILYK 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 266 EISDILEIARSRNEPpFIIISDGITDPHNLGAVIRTALSAGAHGVVIPKRGGVSVTPAVAAASAGATAYLAVARVTNISE 345
Cdd:TIGR00186 76 DLNDLYKTAKSKKQP-FLLILDEITDPHNLGAILRTAEAFGVDGVILPKRRSAPLNSTVVKTSSGAVEYVPLARVTNLSR 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 346 TIELLKNEGVFVYGASAEG-ENYRRASLSGAVALVIGNEGDGLRRLTRERCDALIGIDMLGAVGSLNASVSAGVLMYEVV 424
Cdd:TIGR00186 155 TITKLKESGFWTVGTDLDAqDTLYQVKLTKPLALVVGNEGEGVSRLIKENCDFLIKIPMAGKVDSLNVSVAAGILLFEIK 234
|
...
gi 2319736509 425 RAR 427
Cdd:TIGR00186 235 RQR 237
|
|
| SpoU-like_RlmB |
cd18103 |
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the ... |
282-423 |
6.05e-60 |
|
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the methylation of guanosine 2251, a modification conserved in the peptidyltransferase domain of 23S rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349976 Cd Length: 143 Bit Score: 191.83 E-value: 6.05e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 282 FIIISDGITDPHNLGAVIRTALSAGAHGVVIPKRGGVSVTPAVAAASAGATAYLAVARVTNISETIELLKNEGVFVYGAS 361
Cdd:cd18103 1 LLLILDGITDPHNLGAIIRSAEAFGVDGVIIPKRRSAPLTPTVAKASAGALEHLPIARVTNLARALEELKEAGFWIYGAD 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2319736509 362 AEGE-NYRRASLSGAVALVIGNEGDGLRRLTRERCDALIGIDMLGAVGSLNASVSAGVLMYEV 423
Cdd:cd18103 81 GEAEkSLYDVDLTGPLALVLGSEGKGLRRLVLKNCDFLVKIPMAGKVDSLNVSVAAGIILYEI 143
|
|
| PRK11181 |
PRK11181 |
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB; |
215-429 |
1.03e-51 |
|
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB;
Pssm-ID: 183021 [Multi-domain] Cd Length: 244 Bit Score: 174.00 E-value: 1.03e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 215 LSDIIALARDRGIPVKEVSRDKLDricgfnGMSGGGRNGGVVLEVASA-QYVE--ISDILEiarsRNEPPFIIISDGITD 291
Cdd:PRK11181 36 LLPLINELEAQGIVIQLANRQTLD------EKAEGAVHQGIIARVKPGrQLQEndLPDLLA----SLEQPFLLILDGVTD 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 292 PHNLGAVIRTALSAGAHGVVIPKRGGVSVTPAVAAASAGATAYLAVARVTNISETIELLKNEGVFVYGASAEGEN--YrR 369
Cdd:PRK11181 106 PHNLGACLRSADAAGVHAVIVPKDRSAQLNATAKKVACGAAETVPLIRVTNLARTMRMLQEKNIWIVGTAGEADHtlY-Q 184
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 370 ASLSGAVALVIGNEGDGLRRLTRERCDALIGIDMLGAVGSLNASVSAGVLMYEVVRARAG 429
Cdd:PRK11181 185 SKLTGPLALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGICLFEAVRQRSA 244
|
|
| SpoU_methylase |
pfam00588 |
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet. |
281-421 |
5.23e-42 |
|
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet.
Pssm-ID: 425768 Cd Length: 142 Bit Score: 144.98 E-value: 5.23e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 281 PFIIISDGITDPHNLGAVIRTALSAGAHGVVIPKRGGVS-VTPAVAAASAGATAYLAVARVTNISETIELLKNEGVFVYG 359
Cdd:pfam00588 1 PLVVVLDNIQDPGNLGAIIRTAAAFGADGLILVEPRSADpYNPKAIRASAGALFHLPLVVVDNLEEALKDLKEAGYAVVA 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2319736509 360 ASAEGENYRRASLSGAVALVIGNEGDGLRRLTRERCDALIGIDMLGAVGSLNASVSAGVLMY 421
Cdd:pfam00588 81 TSLGGKSLYEIDFPKKVALVFGNEGTGLSNEVLELCDRLVRIPMSGDVESLNVAVAAAIALY 142
|
|
| SpoU_sub_bind |
smart00967 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
187-242 |
8.05e-10 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 214943 [Multi-domain] Cd Length: 70 Bit Score: 54.85 E-value: 8.05e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 2319736509 187 VYGRNPVREYLNCGQSANVLY-TAVGVGGLSDIIALARDRGIPVKEVSRDKLDRICG 242
Cdd:smart00967 1 IEGRHAVEEALKSGRRIKELYlTEGRAERLKELLKLAKERGIKVIEVSKKELDKLSG 57
|
|
| PTZ00395 |
PTZ00395 |
Sec24-related protein; Provisional |
7-186 |
1.09e-05 |
|
Sec24-related protein; Provisional
Pssm-ID: 185594 [Multi-domain] Cd Length: 1560 Bit Score: 48.15 E-value: 1.09e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 7 YSKPQGAGKPhgggksfggaksYGGKPHGDNSYGSKPRGDNPYGGKPHSDNPYGGGKPSRAGTSFVRGNA---HGADEPR 83
Cdd:PTZ00395 424 YNNAPNSNTP------------YNNPPNSNTPYSNPPNSNPPYSNLPYSNTPYSNAPLSNAPPSSAKDHHsayHAAYQHR 491
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 84 ADGSPRDSKPQGGNPrDGKPFGGnkpfGAGRSYGND--TKPRGGKPrYSHTPRYARDNALAQPRtpRDNalAQARTPRDT 161
Cdd:PTZ00395 492 AANQPAANLPTANQP-AANNFHG----AAGNSVGNPfaSRPFGSAP-YGGNAATTADPNGIAKR--EDH--PEGGTNRQK 561
|
170 180
....*....|....*....|....*
gi 2319736509 162 HDTHDTRDIpDDTSAEPASESADNL 186
Cdd:PTZ00395 562 YEQSDEESV-ESSSSENSSENENEV 585
|
|
| Pro-rich |
pfam15240 |
Proline-rich protein; This family includes several eukaryotic proline-rich proteins. |
6-98 |
1.33e-03 |
|
Proline-rich protein; This family includes several eukaryotic proline-rich proteins.
Pssm-ID: 464580 [Multi-domain] Cd Length: 167 Bit Score: 39.25 E-value: 1.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 6 QYSKPQGAGKPHGGGKSFGGAKSYGGKPHGDNSYGSKPRGDNPYGGKPHSDNPYGGGKPSRAgtsfvrGNAHGADEPRAd 85
Cdd:pfam15240 74 QQPPPQGGKQKPQGPPPQGGPRPPPGKPQGPPPQGGNQQQGPPPPGKPQGPPPQGGGPPPQG------GNQQGPPPPPP- 146
|
90
....*....|....*.
gi 2319736509 86 GSPRDS---KPQGGNP 98
Cdd:pfam15240 147 GNPQGPpqrPPQPGNP 162
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| SpoU |
COG0566 |
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA ... |
168-429 |
5.83e-77 |
|
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA G18 (ribose-2'-O)-methylase SpoU is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440332 [Multi-domain] Cd Length: 265 Bit Score: 240.10 E-value: 5.83e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 168 RDIPDDTSAEPASESADNLVYGRNPVREYLNCGQSANVLYTAVGV-GGLSDIIALARDRGIPVKEVSRDKLDRICGFngm 246
Cdd:COG0566 10 KDLRKLRDKKYREEEGLFLAEGRHAVEEALKAGREIEELLVTEGAlDRLAELLALAKAAGIPVYEVSREVLDKLSGT--- 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 247 sggGRNGGVVLEVASAQYVEISDILEiarSRNEPPFIIISDGITDPHNLGAVIRTALSAGAHGVVIPKRGGVSVTPavaa 326
Cdd:COG0566 87 ---ETHQGVLAVVRPPEYADLEDLLA---EAGEPPLLLVLDGVQDPGNLGAILRSAAAFGVDGVILPKRRADPYNP---- 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 327 asagatA----------YLAVARVTNISETIELLKNEGVFVYGASAEGE-NYRRASLSGAVALVIGNEGDGLRRLTRERC 395
Cdd:COG0566 157 ------KvvrasagalfHVPVARVTNLADALEELKEAGFWVVGTDLDGEaSLYEVDLPGPVALVLGNEGKGLSRLVLEAC 230
|
250 260 270
....*....|....*....|....*....|....
gi 2319736509 396 DALIGIDMLGAVGSLNASVSAGVLMYEVVRARAG 429
Cdd:COG0566 231 DELVRIPMAGGVESLNVAVAAAILLYEAARQRRA 264
|
|
| rRNA_methyl_3 |
TIGR00186 |
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases ... |
186-427 |
6.04e-63 |
|
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129290 [Multi-domain] Cd Length: 237 Bit Score: 202.96 E-value: 6.04e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 186 LVYGRNPVREYLNCGQSANVLYTAVGvGGLSDIIALARDRGIPVKEVSRDKLDRIcgfngmSGGGRNGGVVLEVASAQYV 265
Cdd:TIGR00186 3 YLYGKNAVLEALLNQQRVFILKGLES-KRLKKLIQLAKKQGINIQLVDRQKLDQL------TKGGNHQGIAAKVKPILYK 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 266 EISDILEIARSRNEPpFIIISDGITDPHNLGAVIRTALSAGAHGVVIPKRGGVSVTPAVAAASAGATAYLAVARVTNISE 345
Cdd:TIGR00186 76 DLNDLYKTAKSKKQP-FLLILDEITDPHNLGAILRTAEAFGVDGVILPKRRSAPLNSTVVKTSSGAVEYVPLARVTNLSR 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 346 TIELLKNEGVFVYGASAEG-ENYRRASLSGAVALVIGNEGDGLRRLTRERCDALIGIDMLGAVGSLNASVSAGVLMYEVV 424
Cdd:TIGR00186 155 TITKLKESGFWTVGTDLDAqDTLYQVKLTKPLALVVGNEGEGVSRLIKENCDFLIKIPMAGKVDSLNVSVAAGILLFEIK 234
|
...
gi 2319736509 425 RAR 427
Cdd:TIGR00186 235 RQR 237
|
|
| SpoU-like_RlmB |
cd18103 |
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the ... |
282-423 |
6.05e-60 |
|
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the methylation of guanosine 2251, a modification conserved in the peptidyltransferase domain of 23S rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349976 Cd Length: 143 Bit Score: 191.83 E-value: 6.05e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 282 FIIISDGITDPHNLGAVIRTALSAGAHGVVIPKRGGVSVTPAVAAASAGATAYLAVARVTNISETIELLKNEGVFVYGAS 361
Cdd:cd18103 1 LLLILDGITDPHNLGAIIRSAEAFGVDGVIIPKRRSAPLTPTVAKASAGALEHLPIARVTNLARALEELKEAGFWIYGAD 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2319736509 362 AEGE-NYRRASLSGAVALVIGNEGDGLRRLTRERCDALIGIDMLGAVGSLNASVSAGVLMYEV 423
Cdd:cd18103 81 GEAEkSLYDVDLTGPLALVLGSEGKGLRRLVLKNCDFLVKIPMAGKVDSLNVSVAAGIILYEI 143
|
|
| PRK11181 |
PRK11181 |
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB; |
215-429 |
1.03e-51 |
|
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB;
Pssm-ID: 183021 [Multi-domain] Cd Length: 244 Bit Score: 174.00 E-value: 1.03e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 215 LSDIIALARDRGIPVKEVSRDKLDricgfnGMSGGGRNGGVVLEVASA-QYVE--ISDILEiarsRNEPPFIIISDGITD 291
Cdd:PRK11181 36 LLPLINELEAQGIVIQLANRQTLD------EKAEGAVHQGIIARVKPGrQLQEndLPDLLA----SLEQPFLLILDGVTD 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 292 PHNLGAVIRTALSAGAHGVVIPKRGGVSVTPAVAAASAGATAYLAVARVTNISETIELLKNEGVFVYGASAEGEN--YrR 369
Cdd:PRK11181 106 PHNLGACLRSADAAGVHAVIVPKDRSAQLNATAKKVACGAAETVPLIRVTNLARTMRMLQEKNIWIVGTAGEADHtlY-Q 184
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 370 ASLSGAVALVIGNEGDGLRRLTRERCDALIGIDMLGAVGSLNASVSAGVLMYEVVRARAG 429
Cdd:PRK11181 185 SKLTGPLALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGICLFEAVRQRSA 244
|
|
| SpoU_methylase |
pfam00588 |
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet. |
281-421 |
5.23e-42 |
|
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet.
Pssm-ID: 425768 Cd Length: 142 Bit Score: 144.98 E-value: 5.23e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 281 PFIIISDGITDPHNLGAVIRTALSAGAHGVVIPKRGGVS-VTPAVAAASAGATAYLAVARVTNISETIELLKNEGVFVYG 359
Cdd:pfam00588 1 PLVVVLDNIQDPGNLGAIIRTAAAFGADGLILVEPRSADpYNPKAIRASAGALFHLPLVVVDNLEEALKDLKEAGYAVVA 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2319736509 360 ASAEGENYRRASLSGAVALVIGNEGDGLRRLTRERCDALIGIDMLGAVGSLNASVSAGVLMY 421
Cdd:pfam00588 81 TSLGGKSLYEIDFPKKVALVFGNEGTGLSNEVLELCDRLVRIPMSGDVESLNVAVAAAIALY 142
|
|
| SpoU-like_rRNA-MTase |
cd18095 |
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
282-422 |
3.68e-38 |
|
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349968 Cd Length: 143 Bit Score: 134.86 E-value: 3.68e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 282 FIIISDGITDPHNLGAVIRTALSAGAHGVVI---------PK-----RGGVSvtpavaaasagataYLAVARVTNISETI 347
Cdd:cd18095 1 LVLVLDGVQDPGNLGTIIRTAAAFGVDGVILskgtvdpynPKvvrasMGALF--------------RLPIIRVDDLEELL 66
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2319736509 348 ELLKNEGVFVYGASAEGE-NYRRASLSGAVALVIGNEGDGLRRLTRERCDALIGIDMLGAVGSLNASVSAGVLMYE 422
Cdd:cd18095 67 EELKEAGYKVVAADLDGGsSLYDLDLPKPVALVLGNEGNGLSDELLELCDKRVTIPMSGGVESLNVAVAAAILLYE 142
|
|
| SpoU-like_MRM1 |
cd18105 |
SAM-dependent rRNA methylase related to MRM1; MRM1 catalyzes the methylation of 2'-O-ribose ... |
282-422 |
3.03e-26 |
|
SAM-dependent rRNA methylase related to MRM1; MRM1 catalyzes the methylation of 2'-O-ribose residues G1145 to GmG residue of the mitochondrial 16S rRNA. MRM1 is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349978 Cd Length: 158 Bit Score: 103.37 E-value: 3.03e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 282 FIIISDGITDPHNLGAVIRTALSAGAHGVVIPKRGGVSVTPAVAAASAGATAYLAVARVTNISETIELLKNEGVFVYGAS 361
Cdd:cd18105 1 LWLLLDEITDPQNLGAILRSAYFLGVDGVVVSSKNSAPLSPVVSKASAGALELMPIYSVDNLASFLKSSKENGWKVVGTS 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2319736509 362 AEG-----------ENYRRASLSGAVALVIGNEGDGLRRLTRERCDALIGIDMLGA-----VGSLNASVSAGVLMYE 422
Cdd:cd18105 81 APPsassdkktipaNELSELLLEKPTILVLGNEGRGLRTNIKNLCDYLVSIPGGRSaenpgVDSLNVSVAAGILLHS 157
|
|
| SpoU-like_RNA-MTase |
cd18104 |
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
282-427 |
2.20e-25 |
|
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349977 Cd Length: 146 Bit Score: 100.73 E-value: 2.20e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 282 FIIISDGITDPHNLGAVIRTALSAGAHGVVI---------PK-----RGGVSVTPavaaasagatayLAVArvtNISETI 347
Cdd:cd18104 1 LILVLEGLEKPGNLGAILRSADAAGADAVILcdpktdlfnPNvirasLGAVFTLP------------VAEA---SSEETL 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 348 ELLKNEGVFVYGASAEGE-NYRRASLSGAVALVIGNEGDGLRRLTRERCDALIGIDMLGAVGSLNASVSAGVLMYEVVRA 426
Cdd:cd18104 66 AWLKENKIRILATTPKAEkLYYEADLRGPIAIVVGSESEGLSEFWLKAADERVRIPMAGQADSLNVSVAAAILLYEALRQ 145
|
.
gi 2319736509 427 R 427
Cdd:cd18104 146 R 146
|
|
| SpoU-like_family |
cd18082 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
283-422 |
9.91e-24 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349955 Cd Length: 145 Bit Score: 96.14 E-value: 9.91e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 283 IIISDGITDPHNLGAVIRTALSAGAHGVVIPKRGGVSVTPAVAAASAGATAYLAVARVTNISETIELLKNEGVFVYG--A 360
Cdd:cd18082 1 HLVLDNIRSPGNIGSIFRTADAFGVEKIYLVGPTADIFDPKAKRTSRGTHFSVPYERVDNFEEYLKSLKEEGYPLIGleL 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2319736509 361 SAEGENYRRA--SLSGAVALVIGNEGDGLRRLTRERCDALIGIDMLGAVGSLNASVSAGVLMYE 422
Cdd:cd18082 81 TDGSIPLSEFkfKKPKKIALIFGNERSGLSPELLALCDYTVHIPMSGKNSSLNVSVATGIALYE 144
|
|
| SpoU-like_TrmH |
cd18092 |
SAM-dependent tRNA methylase related to TrmH; TrmH catalyzes the transfer of the methyl group ... |
267-427 |
2.63e-22 |
|
SAM-dependent tRNA methylase related to TrmH; TrmH catalyzes the transfer of the methyl group from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of the ribose of the universally conserved guanosine 18 (G18) position in tRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349965 Cd Length: 162 Bit Score: 92.92 E-value: 2.63e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 267 ISDILEiARSRNeppFIIISDGITDPHNLGAVIRTALSAGAHGV-VIPKRGGVSVTPAVAAASAGataYLAVARVTNISE 345
Cdd:cd18092 6 IEEVLA-RRTRD---LTVVLENVHDPHNASAVLRTCDAFGVQDVhVIEPKNKFKKNRGVAMGADK---WLDVHRHDSTEE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 346 TIELLKNEGVFVYGAS--AEGENYRRASLSGAVALVIGNEGDGLRRLTRERCDALIGIDMLGAVGSLNASVSAGVLMYEV 423
Cdd:cd18092 79 CLAALKEQGYRIVATSlsPDAVPLDELDYTRPTALVFGNEKDGVSEEALAAADERVYIPMYGFVESLNVSVAAAIILYEL 158
|
....
gi 2319736509 424 VRAR 427
Cdd:cd18092 159 QRQR 162
|
|
| SpoU-like |
cd18097 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
283-423 |
2.93e-18 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349970 Cd Length: 144 Bit Score: 81.07 E-value: 2.93e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 283 IIISDGITDPHNLGAVIRTALSAGAHGVVIpkrGGVSVTPAVAAASAGA---TAYLAVARVTNISETIELLKNEGVFVYG 359
Cdd:cd18097 2 VVVLDNLRSAHNVGSIFRTADAAGVEKIYL---CGYTPTPPHPKVAKTAlgaEESVPWEHFEDTLEAVRALKARGYTIIA 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2319736509 360 A--SAEGENYRRASLSGAVALVIGNEGDGLRRLTRERCDALIGIDMLGAVGSLNASVSAGVLMYEV 423
Cdd:cd18097 79 LetTENSVPLHEARLPRPLALVLGNEVRGVSPEVLALCDAVVEIPMFGRKNSLNVAVAAAVALYEL 144
|
|
| SpoU-like_AviRb |
cd18107 |
SAM-dependent rRNA methylase related to AviRb; AviRb from Streptomyces viridochromogenes ... |
282-423 |
6.62e-17 |
|
SAM-dependent rRNA methylase related to AviRb; AviRb from Streptomyces viridochromogenes methylates the 2'-O atom of U2479 of the 23S ribosomal RNA. AviRb is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349980 Cd Length: 148 Bit Score: 77.43 E-value: 6.62e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 282 FIIISDGITDPHNLGAVIRTALSAGAHGVVIPKRGGVSVTPAVAAASAGATAYLAVARVTNISETIELLKNE-----GVF 356
Cdd:cd18107 1 LVVLFDRPTSPGNLGTIIRSADALGAHGLVVTGHAADVYDPKTIRASTGSLFSLPIVRVPSNRELEDWVEARkargtPLQ 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2319736509 357 VYGASAEGEN-YRRASLSGAVALVIGNEGDGLRRLTRERCDALIGIDMLGAVGSLNASVSAGVLMYEV 423
Cdd:cd18107 81 LVGTDEHGDHqIADHDFTRPTLLLIGNETAGLSAAWRELCDETVSIPMAGSASSLNAACAASIFLYEA 148
|
|
| SpoU-like_RNA-MTase |
cd18109 |
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
282-422 |
1.08e-15 |
|
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349982 Cd Length: 141 Bit Score: 73.73 E-value: 1.08e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 282 FIIISDGITDPHNLGAVIRTA---------LSAGAHGVVIPKRggVSVTPAvaaasagataylAVARV----TNISETIE 348
Cdd:cd18109 1 LTLALDGIQDPGNLGTIIRTAdwfgirqiiCSPDTVDPYNPKV--VQASMG------------SIFRVqihyTDLPALLA 66
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2319736509 349 LLKnEGVFVYGASAEGENYRRASLSGAVALVIGNEGDGLRRLTRERCDALIGIDMLG-AVGSLNASVSAGVLMYE 422
Cdd:cd18109 67 ELK-KAFPVYGADLDGENLYEFTLPEKGILVMGNEGHGISPEVLKLLTHRLTIPRYGkGAESLNVAVATAILLSE 140
|
|
| SpoU-like |
cd18096 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
282-422 |
3.35e-12 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349969 Cd Length: 140 Bit Score: 63.77 E-value: 3.35e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 282 FIIISDGITDPHNLGAVIRTALSAGAHGVVIPKRGGVSVTPavaaaSAGATAYLAVARVTNISETIELLKNEGVFVYG-- 359
Cdd:cd18096 1 LYLVLHNVAKRHNIGTIVRSANAFGVKEVHLVGRRKFNPFG-----AMGTDRHVKFRHFDTLAEAKEYLKERGIRLVGve 75
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2319736509 360 ASAEGENYRRASLSGAVALVIGNEGDGLRRLTRERCDALIGIDMLG-AVGSLNASVSAGVLMYE 422
Cdd:cd18096 76 IVPGAEPIETHPFPGDTAFVLGNEGTGLSDEQLAICDGFVYIPQYGsGTASLNVSVAASIVLHH 139
|
|
| PRK10864 |
PRK10864 |
putative methyltransferase; Provisional |
287-429 |
2.61e-11 |
|
putative methyltransferase; Provisional
Pssm-ID: 236779 [Multi-domain] Cd Length: 346 Bit Score: 64.41 E-value: 2.61e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 287 DGITDPHNLGAVIRTALSAGAHGVVIPKRG----GVSVtpavaAASAGATAYLAVARVTNISETIELLKNEG-VFVYGAS 361
Cdd:PRK10864 204 EDVGNPHNLGGIMRSCAHFGVKGVVVQDAAllesGAAI-----RTAEGGAEHVQPITGDSFVDVLDDFRQAGyTIVTTSS 278
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2319736509 362 AEGENYRRASLSGAVALVIGNEGDGLRRLTRERCDALIGIDMLGAVGSLNASVSAGVLMYEVVRARAG 429
Cdd:PRK10864 279 HKGTPLFKASLPAKMVLVLGQEYDGLSDAARQQGDLSVSIDGTGNVESLNVSVATGVLLAEWWRQNKA 346
|
|
| SpoU-like_RNMTL1 |
cd18106 |
SAM-dependent rRNA methylase related to RNMTL1; RNMTL1 (also known as HC90, MRM3 and RMTL1) ... |
283-422 |
1.08e-10 |
|
SAM-dependent rRNA methylase related to RNMTL1; RNMTL1 (also known as HC90, MRM3 and RMTL1) catalyzes the methylation of 2'-O-ribose residues G1370 to GmG residue of the mitochondrial 16S rRNA. RNMTL1 is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349979 Cd Length: 148 Bit Score: 59.57 E-value: 1.08e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 283 IIISDGITDPHNLGAVIRTALSAGAHGVVIPK-----------RGGVSvtpavaaasagatAYLAVARVTNIS-ETIELL 350
Cdd:cd18106 2 TVICDNIRDPGNLGSILRSAAAAGCSKVLLTKgcvdpwepkvlRAGAG-------------AHFRLPIYGNLSwDDIPNY 68
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2319736509 351 KNEGVFVYGASAEGEN---YRRASLSGAVALVIGNEGDGL----RRLTRERCDALIGIDMLGAVGSLNASVSAGVLMYE 422
Cdd:cd18106 69 LPDDSKVFLADNNLPVqpyDSIDYCSGPIVLVIGGETHGVspeaYKLAHSTGGSRVHIPLANGVDSLNSAVAASILLFE 147
|
|
| SpoU_sub_bind |
pfam08032 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
186-242 |
1.16e-10 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 429793 [Multi-domain] Cd Length: 74 Bit Score: 57.25 E-value: 1.16e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 2319736509 186 LVYGRNPVREYLNCGQSANVLYTAVGVGG--LSDIIALARDRGIPVKEVSRDKLDRICG 242
Cdd:pfam08032 1 LIYGRHAVLEALKSGPEIKKLYLTEGRRDprLKELLKLAKERGIKVEEVDRKKLDKLSG 59
|
|
| SpoU_sub_bind |
smart00967 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
187-242 |
8.05e-10 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 214943 [Multi-domain] Cd Length: 70 Bit Score: 54.85 E-value: 8.05e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 2319736509 187 VYGRNPVREYLNCGQSANVLY-TAVGVGGLSDIIALARDRGIPVKEVSRDKLDRICG 242
Cdd:smart00967 1 IEGRHAVEEALKSGRRIKELYlTEGRAERLKELLKLAKERGIKVIEVSKKELDKLSG 57
|
|
| PRK11081 |
PRK11081 |
tRNA guanosine-2'-O-methyltransferase; Provisional |
264-429 |
1.34e-09 |
|
tRNA guanosine-2'-O-methyltransferase; Provisional
Pssm-ID: 236837 [Multi-domain] Cd Length: 229 Bit Score: 58.08 E-value: 1.34e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 264 YVEISDILeiarSRNEPPFIIISDGITDPHNLGAVIRTALSAGAHGV--VIP-KRGGVSVTPAVAAASagataYLAVARV 340
Cdd:PRK11081 6 YARICEML----ARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVhaVWPgSRMRTMGSTAAGSNS-----WVQVKTH 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 341 TNISETIELLKNEG--VFVYGASAEGENYRRASLSGAVALVIGNEGDGLRRLTRERCDALIGIDMLGAVGSLNASVSAGV 418
Cdd:PRK11081 77 RTIGDAVAHLKGQGmqILATHLSDTAVDFREIDYTRPTCILMGQEKTGISQEALALADQDIIIPMIGMVQSLNVSVASAL 156
|
170
....*....|...
gi 2319736509 419 LMYEVVRAR--AG 429
Cdd:PRK11081 157 ILYEAQRQRqnAG 169
|
|
| SpoU-like_NHR |
cd18108 |
Nosiheptide-resistance methyltransferase (NHR); Nosiheptide-resistance methyltransferase (NHR) ... |
283-422 |
5.50e-08 |
|
Nosiheptide-resistance methyltransferase (NHR); Nosiheptide-resistance methyltransferase (NHR) confers resistance to the thiazole antibiotic nosiheptide via catalyzing 2'O-methylation of 23S rRNA at the nucleotide A1067. NHR is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349981 Cd Length: 144 Bit Score: 51.71 E-value: 5.50e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 283 IIISDGITDPHNLGAVIRTALSAGAHGVVIPKRGGVSVTPAVAAASAGATAYLAVARVTNISETIELLKNEGVFVYGASA 362
Cdd:cd18108 2 VVVLDGVRIVGNIGAIVRTSLALGAAGIVLVDSDLATVADRRLLRASRGYVFSLPVVLADREEAVAFLRDNDIPLMTLDA 81
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2319736509 363 EGENYRR--ASLSGAVALVIGNEGDGLRRLTRERCDALIGIDMLGAVGSLNASVSAGVLMYE 422
Cdd:cd18108 82 DGDVPVKelGDRPDRLALVFGSEKGGPSGLFEEAAAGTVSIPMSSSTESLNVSVSAGIALHE 143
|
|
| PTZ00395 |
PTZ00395 |
Sec24-related protein; Provisional |
7-186 |
1.09e-05 |
|
Sec24-related protein; Provisional
Pssm-ID: 185594 [Multi-domain] Cd Length: 1560 Bit Score: 48.15 E-value: 1.09e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 7 YSKPQGAGKPhgggksfggaksYGGKPHGDNSYGSKPRGDNPYGGKPHSDNPYGGGKPSRAGTSFVRGNA---HGADEPR 83
Cdd:PTZ00395 424 YNNAPNSNTP------------YNNPPNSNTPYSNPPNSNPPYSNLPYSNTPYSNAPLSNAPPSSAKDHHsayHAAYQHR 491
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 84 ADGSPRDSKPQGGNPrDGKPFGGnkpfGAGRSYGND--TKPRGGKPrYSHTPRYARDNALAQPRtpRDNalAQARTPRDT 161
Cdd:PTZ00395 492 AANQPAANLPTANQP-AANNFHG----AAGNSVGNPfaSRPFGSAP-YGGNAATTADPNGIAKR--EDH--PEGGTNRQK 561
|
170 180
....*....|....*....|....*
gi 2319736509 162 HDTHDTRDIpDDTSAEPASESADNL 186
Cdd:PTZ00395 562 YEQSDEESV-ESSSSENSSENENEV 585
|
|
| SpoU-like_TrmL |
cd18094 |
SAM-dependent tRNA methylase related to TrmL; tRNA (Um34/Cm34) methyltransferase TrmL ... |
292-425 |
2.14e-05 |
|
SAM-dependent tRNA methylase related to TrmL; tRNA (Um34/Cm34) methyltransferase TrmL catalyzes the methyl transfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH at position 34 in both tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349967 Cd Length: 145 Bit Score: 43.98 E-value: 2.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 292 PHNLGAVIRTALSAGA--HgVVIP----------KRGGVSVTPavaaasagataYLAVARVTNISETIELLKNEGVFvyG 359
Cdd:cd18094 10 PQNTGNIARTCAATGArlH-LIEPlgfslddkrlKRAGLDYWD-----------HVDLTVHDSWEAFLEALPPGRLF--L 75
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2319736509 360 ASAEGE-NYRRASLSGAVALVIGNEGDGLRRLTRERC-DALIGIDMLGAVGSLNASVSAGVLMYEVVR 425
Cdd:cd18094 76 FTTKGTkPYTDFDFKPGDYLVFGRESTGLPEEILDAFpDRRLRIPMRPKVRSLNLSNSVAIVLYEALR 143
|
|
| SpoU-like_TrmJ |
cd18093 |
SAM-dependent tRNA methylase related to TrmJ; tRNA methyltransferase TrmJ catalyzes the methyl ... |
292-422 |
3.28e-05 |
|
SAM-dependent tRNA methylase related to TrmJ; tRNA methyltransferase TrmJ catalyzes the methyl transfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH at position 32 in both tRNASer1 and tRNAGln2. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349966 Cd Length: 153 Bit Score: 43.64 E-value: 3.28e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 292 PHNLGAVIRTALSAGAHGVVIpkrggvsVTPAVAAASAGATAYLAVAR--------VTNISETIELLknegVFVYGASAE 363
Cdd:cd18093 11 PGNIGAVARAMKNFGLSDLRL-------VNPRCDDPEEAARALASGAEdvlenakvYDTLEEALADC----DLVVATTAR 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2319736509 364 GENYRRASLS--------------GAVALVIGNEGDGLrrlTRE---RCDALIGIDMLGAVGSLNASVSAGVLMYE 422
Cdd:cd18093 80 PRGLRRPLLTprelaellkehaagGKVALVFGREDSGL---TNEelaLCDLLVTIPTNPEYPSLNLAQAVAIVLYE 152
|
|
| TrmJ |
COG0565 |
tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase [Translation, ... |
355-430 |
1.59e-04 |
|
tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase [Translation, ribosomal structure and biogenesis]; tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440331 [Multi-domain] Cd Length: 237 Bit Score: 42.80 E-value: 1.59e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 355 VFVYGASAEGENYRRASLS--------------GAVALVIGNEGDGlrrLTRE---RCDALIGIDMLGAVGSLNASVSAG 417
Cdd:COG0565 73 DLVVGTTARPRELRKPVLTpreaaeellaraagGKVALVFGRERSG---LTNEelaLCDALVTIPTNPEYPSLNLAQAVQ 149
|
90
....*....|...
gi 2319736509 418 VLMYEVVRARAGE 430
Cdd:COG0565 150 VVAYELRKAALEA 162
|
|
| TrmL |
COG0219 |
tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain [Translation, ... |
377-425 |
1.97e-04 |
|
tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain [Translation, ribosomal structure and biogenesis]; tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 439989 Cd Length: 153 Bit Score: 41.56 E-value: 1.97e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 2319736509 377 ALVIGNEGDGL-RRLTRERCDALIGIDMLGAVGSLNASVSAGVLMYEVVR 425
Cdd:COG0219 96 VLLFGRETAGLpEEVLAAPADQRLRIPMRPGVRSLNLSNAVAIVLYEALR 145
|
|
| SpoU-like_TRM3-like |
cd18091 |
SAM-dependent tRNA methylase related to TRM3; Yeast tRNA (guanosine(18)-2'-O) ... |
282-422 |
8.33e-04 |
|
SAM-dependent tRNA methylase related to TRM3; Yeast tRNA (guanosine(18)-2'-O)-methyltransferase TRM3 catalyzes the formation of 2'-O-methylguanosine at position 18 (Gm18) in various tRNAs. TRM3 is similar to C-terminal domain of TAR (HIV-1) RNA binding protein 1 (TARBP1), a protein binding to TAR, which functions as a RNA regulatory signal by forming a stable stem-loop structure to which transactivator protein Tat binds. The role of TARBP1 is believed to be to disengage RNA polymerase II from TAR during transcriptional elongation. TRM3 and the C-terminal methyltransferase domain of TARBP1 are members of the SPOUT methyltransferase superfamily.
Pssm-ID: 349964 Cd Length: 145 Bit Score: 39.44 E-value: 8.33e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 282 FIIISDGITDPHNLGAVIRTALSAGAHGVVIPkrgGVSVTPAVAaasagataYLAVARVTNISETIELLKNEGVFVYGAS 361
Cdd:cd18091 1 LIVVASLIDKPPNLGGLCRTCEIFGVSKLVLP---NLAVVEDKQ--------FKALSVSAEKWLPIEEVKPEDLLPYLKE 69
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2319736509 362 AEGENYRRASL---SGAV-----------ALVIGNEGDG----LRRLtrerCDALIGIDMLGAVGSLNASVSAGVLMYE 422
Cdd:cd18091 70 KKQEGYTIVGLeqtANSVslhdfqfpkktVLVLGNEKEGipaeLLSL----LDVCVEIPQLGVIRSLNVHVSGAIAIYE 144
|
|
| Pro-rich |
pfam15240 |
Proline-rich protein; This family includes several eukaryotic proline-rich proteins. |
6-98 |
1.33e-03 |
|
Proline-rich protein; This family includes several eukaryotic proline-rich proteins.
Pssm-ID: 464580 [Multi-domain] Cd Length: 167 Bit Score: 39.25 E-value: 1.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2319736509 6 QYSKPQGAGKPHGGGKSFGGAKSYGGKPHGDNSYGSKPRGDNPYGGKPHSDNPYGGGKPSRAgtsfvrGNAHGADEPRAd 85
Cdd:pfam15240 74 QQPPPQGGKQKPQGPPPQGGPRPPPGKPQGPPPQGGNQQQGPPPPGKPQGPPPQGGGPPPQG------GNQQGPPPPPP- 146
|
90
....*....|....*.
gi 2319736509 86 GSPRDS---KPQGGNP 98
Cdd:pfam15240 147 GNPQGPpqrPPQPGNP 162
|
|
| |
