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Conserved domains on  [gi|2067289280|dbj|GJA24693|]
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lipid A biosynthesis lauroyltransferase [Aeromonas caviae]

Protein Classification

lysophospholipid acyltransferase family protein( domain architecture ID 106732)

lysophospholipid acyltransferase (LPLAT) family protein may act as an acyltransferase of a de novo or remodeling pathway of glycerophospholipid biosynthesis, catalyzing the incorporation of an acyl group from either acyl-CoAs or acyl-acyl carrier proteins (acyl-ACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LPLAT super family cl17185
Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; ...
 1-307 1.14e-139

Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Lysophospholipid acyltransferase (LPLAT) superfamily members are acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis. These proteins catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this superfamily are LPLATs such as glycerol-3-phosphate 1-acyltransferase (GPAT, PlsB), 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), lysophosphatidylcholine acyltransferase 1 (LPCAT-1), lysophosphatidylethanolamine acyltransferase (LPEAT, also known as, MBOAT2, membrane-bound O-acyltransferase domain-containing protein 2), lipid A biosynthesis lauroyl/myristoyl acyltransferase, 2-acylglycerol O-acyltransferase (MGAT), dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and Tafazzin (the protein product of the Barth syndrome (TAZ) gene).


The actual alignment was detected with superfamily member PRK06860:

Pssm-ID: 473073 [Multi-domain]  Cd Length: 309  Bit Score: 396.59  E-value: 1.14e-139
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280   1 MAQEHAPRLEPRLFHPRYWGSWLGLSLLWLLVLLPWRSQMWLGRQLGTLARKLLKSRVKIARRNLELAMPELSRDEREAL 80
Cdd:PRK06860    1 MKMTNLPKFSRALLHPRYWLTWLGIGLLWLIVLLPYPVLYKLGRGLGKLALRFMKRRAKIARRNLELCFPEMSEQEREAI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280  81 LVQNFESVGCAIFEVGMAWFWPDWRMRRLMKVEGEEHVINAMEKGQGMLLLSCHFLTLELNARCFGLVRPGVGVYRPNTN 160
Cdd:PRK06860   81 VVKNFESVGMALIETGMAWFWPDWRIKRWTEVEGLEHIREVQAQGRGVLLVGVHFLTLELGARIFGMHNPGIGVYRPNDN 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280 161 PVLEYAQYHGRCASNKYLVDRMDVKGMIKALRNGDALWYAPDHDYGSHASVFVPYFAVEQAATITGTATLARVKNTVTLP 240
Cdd:PRK06860  161 PLYDWLQTWGRLRSNKSMLDRKDLKGMIKALKKGERIWYAPDHDYGPRSSVFVPFFAVEQAATTTGTWMLARMSKAAVIP 240

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2067289280 241 CYNIRTRE--GYTLHIGAPLADYPSGDDMADASRANREIEAAVRKAPEQYMWLHRRFKTRPnPDDPGYY 307
Cdd:PRK06860  241 FVPRRKPDgkGYELIILPPEDSPPLDDAEATAAWMNKVVEKCILMAPEQYMWLHRRFKTRP-EGVPSRY 308
 
Name Accession Description Interval E-value
PRK06860 PRK06860
lipid A biosynthesis lauroyl acyltransferase; Provisional
 1-307 1.14e-139

lipid A biosynthesis lauroyl acyltransferase; Provisional


Pssm-ID: 235880 [Multi-domain]  Cd Length: 309  Bit Score: 396.59  E-value: 1.14e-139
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280   1 MAQEHAPRLEPRLFHPRYWGSWLGLSLLWLLVLLPWRSQMWLGRQLGTLARKLLKSRVKIARRNLELAMPELSRDEREAL 80
Cdd:PRK06860    1 MKMTNLPKFSRALLHPRYWLTWLGIGLLWLIVLLPYPVLYKLGRGLGKLALRFMKRRAKIARRNLELCFPEMSEQEREAI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280  81 LVQNFESVGCAIFEVGMAWFWPDWRMRRLMKVEGEEHVINAMEKGQGMLLLSCHFLTLELNARCFGLVRPGVGVYRPNTN 160
Cdd:PRK06860   81 VVKNFESVGMALIETGMAWFWPDWRIKRWTEVEGLEHIREVQAQGRGVLLVGVHFLTLELGARIFGMHNPGIGVYRPNDN 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280 161 PVLEYAQYHGRCASNKYLVDRMDVKGMIKALRNGDALWYAPDHDYGSHASVFVPYFAVEQAATITGTATLARVKNTVTLP 240
Cdd:PRK06860  161 PLYDWLQTWGRLRSNKSMLDRKDLKGMIKALKKGERIWYAPDHDYGPRSSVFVPFFAVEQAATTTGTWMLARMSKAAVIP 240

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2067289280 241 CYNIRTRE--GYTLHIGAPLADYPSGDDMADASRANREIEAAVRKAPEQYMWLHRRFKTRPnPDDPGYY 307
Cdd:PRK06860  241 FVPRRKPDgkGYELIILPPEDSPPLDDAEATAAWMNKVVEKCILMAPEQYMWLHRRFKTRP-EGVPSRY 308
lipid_A_htrB TIGR02207
lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase; This model represents a narrow ...
 7-307 4.92e-139

lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase; This model represents a narrow clade of acyltransferases, nearly all of which transfer a lauroyl group to KDO2-lipid IV-A, a lipid A precursor; these proteins are termed lipid A biosynthesis lauroyl acyltransferase, HtrB. An exception is a closely related paralog of E. coli HtrB, LpxP, which acts in cold shock conditions by transferring a palmitoleoyl rather than lauroyl group to the lipid A precursor. Members of this family are homologous to the family of acyltransferases responsible for the next step in lipid A biosynthesis. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 274031 [Multi-domain]  Cd Length: 303  Bit Score: 394.78  E-value: 4.92e-139
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280   7 PRLEPRLFHPRYWGSWLGLSLLWLLVLLPWRSQMWLGRQLGTLARKLLKSRVKIARRNLELAMPELSRDEREALLVQNFE 86
Cdd:TIGR02207   1 PEFSASLLHPRYWPTWLGLGVLWLIVQLPYPVLLALGRGIGRLAMRLMKRRVHIARRNLELCFPHMSDAERERLLRENFE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280  87 SVGCAIFEVGMAWFWPDWRMRRLMKVEGEEHVINAMEKGQGMLLLSCHFLTLELNARCFGLVRPGVGVYRPNTNPVLEYA 166
Cdd:TIGR02207  81 STGMALFETGMAWFWSDARIKKWMQIEGLEHLQRAQKQGRGVLLVGVHFLTLELGARIFGQQQPGIGVYRPHNNPLFDWI 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280 167 QYHGRCASNKYLVDRMDVKGMIKALRNGDALWYAPDHDYGSHASVFVPYFAVEQAATITGTATLARVKNTVTLPCYNIRT 246
Cdd:TIGR02207 161 QTRGRLRSNKAMIDRKDLRGMIKALKNGERIWYAPDHDYGRKSSVFVPFFAVPDAATTTGTSILARLSKCAVVPFTPRRN 240

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2067289280 247 RE--GYTLHIGAPLADYPSGDDMADASRANREIEAAVRKAPEQYMWLHRRFKTRPNPDDPGYY 307
Cdd:TIGR02207 241 EDgsGYRLKIDPPLDDFPGDDEIAAAARMNKIVEKMIMRAPEQYMWLHRRFKTRPDEGESSLY 303
LpxP COG1560
Palmitoleoyl-ACP: Kdo2-lipid-IV acyltransferase (lipid A biosynthesis) [Lipid transport and ...
 35-295 2.08e-98

Palmitoleoyl-ACP: Kdo2-lipid-IV acyltransferase (lipid A biosynthesis) [Lipid transport and metabolism]; Palmitoleoyl-ACP: Kdo2-lipid-IV acyltransferase (lipid A biosynthesis) is part of the Pathway/BioSystem: Lipid A biosynthesis


Pssm-ID: 441168 [Multi-domain]  Cd Length: 271  Bit Score: 290.55  E-value: 2.08e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280  35 PWRSQMWLGRQLGTLARKLLKSRVKIARRNLELAMPELSRDEREALLVQNFESVGCAIFEVGMAWFWPDWRMRRLMKVEG 114
Cdd:COG1560     9 PLRLLYRLGDLLGRLLYRLAGRRRRVARRNLALAFPELSEAEREALARASFRNLGRTLLETLRLWRLSPERLRKRVEVEG 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280 115 EEHVINAMEKGQGMLLLSCHFLTLELNARCFGLV-RPGVGVYRPNTNPVLEYAQYHGRCASNKYLVDRMD-VKGMIKALR 192
Cdd:COG1560    89 LEHLEAALAEGRGVILLTPHFGNWELAGAALALRgYPVTAVYRPLKNPLLDRLIRRGRERFGGELIPRKDgVRALLRALR 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280 193 NGDALWYAPDHDYGSHASVFVPYFAVEqAATITGTATLARVKNTVTLPCYNIRTREG--YTLHIGAPLADyPSGDDMADA 270
Cdd:COG1560   169 KGGIVGLLPDQDPGRKSGVFVPFFGVP-AATPTGPARLARRTGAPVVPVFARRLPDGrgYRLEIEPPLED-FSEDVEADT 246

                         250       260
                  ....*....|....*....|....*
gi 2067289280 271 SRANREIEAAVRKAPEQYMWLHRRF 295
Cdd:COG1560   247 QRLNRALEAWIREHPEQWLWLHRRW 271
Lip_A_acyltrans pfam03279
Bacterial lipid A biosynthesis acyltransferase;
7-297 3.53e-78

Bacterial lipid A biosynthesis acyltransferase;


Pssm-ID: 281296 [Multi-domain]  Cd Length: 294  Bit Score: 239.94  E-value: 3.53e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280   7 PRLEPRLFHPRYWGSWLGLSLLWLLVLLPWRSQMWLGRQLGTLARKLLKSRVKIARRNLELAMPELSRDEREALLVQNFE 86
Cdd:pfam03279   1 PKFSPELLHPRYWLDWLGIAVLRLLALLPYSALRRIGKGLGRLAGRFLKRRRKIARRNLALCFPEMSEAEREQIIDKSFA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280  87 SVGCAIFEVGMAWFWPDWRMRRLMKVEGEEHVINAMEKGQGMLLLSCHFLTLELNARCFGLVRPGVGVYRPNT-NPVLEY 165
Cdd:pfam03279  81 SVGRAIVETGRVWFWPDSRIAKRFEVIGLEHIKEALAQGRGAILVGPHFGNWDLGGRVLGQQYPGMAVYRPNLkNPLLDW 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280 166 AQYHGRCASNKYLVDRMD-VKGMIKALRNGDALWYAPDHDYGSHASVFVPYFAVEQAATiTGTATLARVKNTVTLPCYNI 244
Cdd:pfam03279 161 LQTSGRERFGGRMLPRQNgIKGLIKALRKGEVVWYLPDQDLGRKDSVFVPFFGVPAATT-TGPAKLALKTKAAVIPVFPI 239

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2067289280 245 RTREG--YTLHIGAPLADYPSGDDMADASRANREIEAAVRKAPEQYMWLHRRFKT 297
Cdd:pfam03279 240 RNGDGsgYTVIVHPALDLTITDDVEQIAQAMNQIVEKFIMPAPEQYFWLHRRWKT 294
LPLAT_LABLAT-like cd07984
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; ...
 107-296 5.06e-64

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as lipid A biosynthesis lauroyl/myristoyl (LABLAT, HtrB) acyltransferases and similar proteins.


Pssm-ID: 153246 [Multi-domain]  Cd Length: 192  Bit Score: 200.13  E-value: 5.06e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280 107 RRLMKVEGEEHVINAMEKGQGMLLLSCHFLTLELNARCFGL-VRPGVGVYRPNTNPVLEYAQYHGRCASNKYLVDR-MDV 184
Cdd:cd07984     1 LKRVEREGLEHLEAALAKGKGVILLTAHFGNWELAGLALALlGYPVTVVYRPLKNPLLDRLITRGRERFGARLIPRgGGL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280 185 KGMIKALRNGDALWYAPDHDYGSHASVFVPyFAVEQAATITGTATLARVKNTVTLPCYNIRT-REGYTLHIGAPLADYPS 263
Cdd:cd07984    81 RELIRALKKGEIVGILPDQDPGRKGGVFVP-FFGRPAATPTGPARLALKTGAPVVPAFAYRLpGGGYRIEFEPPLENPPS 159

                         170       180       190
                  ....*....|....*....|....*....|...
gi 2067289280 264 GDDMADASRANREIEAAVRKAPEQYMWLHRRFK 296
Cdd:cd07984   160 EDVEEDTQRLNDALEAAIREHPEQWLWFHRRWK 192
 
Name Accession Description Interval E-value
PRK06860 PRK06860
lipid A biosynthesis lauroyl acyltransferase; Provisional
 1-307 1.14e-139

lipid A biosynthesis lauroyl acyltransferase; Provisional


Pssm-ID: 235880 [Multi-domain]  Cd Length: 309  Bit Score: 396.59  E-value: 1.14e-139
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280   1 MAQEHAPRLEPRLFHPRYWGSWLGLSLLWLLVLLPWRSQMWLGRQLGTLARKLLKSRVKIARRNLELAMPELSRDEREAL 80
Cdd:PRK06860    1 MKMTNLPKFSRALLHPRYWLTWLGIGLLWLIVLLPYPVLYKLGRGLGKLALRFMKRRAKIARRNLELCFPEMSEQEREAI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280  81 LVQNFESVGCAIFEVGMAWFWPDWRMRRLMKVEGEEHVINAMEKGQGMLLLSCHFLTLELNARCFGLVRPGVGVYRPNTN 160
Cdd:PRK06860   81 VVKNFESVGMALIETGMAWFWPDWRIKRWTEVEGLEHIREVQAQGRGVLLVGVHFLTLELGARIFGMHNPGIGVYRPNDN 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280 161 PVLEYAQYHGRCASNKYLVDRMDVKGMIKALRNGDALWYAPDHDYGSHASVFVPYFAVEQAATITGTATLARVKNTVTLP 240
Cdd:PRK06860  161 PLYDWLQTWGRLRSNKSMLDRKDLKGMIKALKKGERIWYAPDHDYGPRSSVFVPFFAVEQAATTTGTWMLARMSKAAVIP 240

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2067289280 241 CYNIRTRE--GYTLHIGAPLADYPSGDDMADASRANREIEAAVRKAPEQYMWLHRRFKTRPnPDDPGYY 307
Cdd:PRK06860  241 FVPRRKPDgkGYELIILPPEDSPPLDDAEATAAWMNKVVEKCILMAPEQYMWLHRRFKTRP-EGVPSRY 308
lipid_A_htrB TIGR02207
lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase; This model represents a narrow ...
 7-307 4.92e-139

lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase; This model represents a narrow clade of acyltransferases, nearly all of which transfer a lauroyl group to KDO2-lipid IV-A, a lipid A precursor; these proteins are termed lipid A biosynthesis lauroyl acyltransferase, HtrB. An exception is a closely related paralog of E. coli HtrB, LpxP, which acts in cold shock conditions by transferring a palmitoleoyl rather than lauroyl group to the lipid A precursor. Members of this family are homologous to the family of acyltransferases responsible for the next step in lipid A biosynthesis. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 274031 [Multi-domain]  Cd Length: 303  Bit Score: 394.78  E-value: 4.92e-139
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280   7 PRLEPRLFHPRYWGSWLGLSLLWLLVLLPWRSQMWLGRQLGTLARKLLKSRVKIARRNLELAMPELSRDEREALLVQNFE 86
Cdd:TIGR02207   1 PEFSASLLHPRYWPTWLGLGVLWLIVQLPYPVLLALGRGIGRLAMRLMKRRVHIARRNLELCFPHMSDAERERLLRENFE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280  87 SVGCAIFEVGMAWFWPDWRMRRLMKVEGEEHVINAMEKGQGMLLLSCHFLTLELNARCFGLVRPGVGVYRPNTNPVLEYA 166
Cdd:TIGR02207  81 STGMALFETGMAWFWSDARIKKWMQIEGLEHLQRAQKQGRGVLLVGVHFLTLELGARIFGQQQPGIGVYRPHNNPLFDWI 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280 167 QYHGRCASNKYLVDRMDVKGMIKALRNGDALWYAPDHDYGSHASVFVPYFAVEQAATITGTATLARVKNTVTLPCYNIRT 246
Cdd:TIGR02207 161 QTRGRLRSNKAMIDRKDLRGMIKALKNGERIWYAPDHDYGRKSSVFVPFFAVPDAATTTGTSILARLSKCAVVPFTPRRN 240

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2067289280 247 RE--GYTLHIGAPLADYPSGDDMADASRANREIEAAVRKAPEQYMWLHRRFKTRPNPDDPGYY 307
Cdd:TIGR02207 241 EDgsGYRLKIDPPLDDFPGDDEIAAAARMNKIVEKMIMRAPEQYMWLHRRFKTRPDEGESSLY 303
PRK08025 PRK08025
kdo(2)-lipid IV(A) palmitoleoyltransferase;
7-299 3.78e-100

kdo(2)-lipid IV(A) palmitoleoyltransferase;


Pssm-ID: 181200  Cd Length: 305  Bit Score: 296.26  E-value: 3.78e-100
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280   7 PRLEPRLFHPRYWGSWLGLSLLWLLVLLPWRSQMWLGRQLGTLARKLLKSRVKIARRNLELAMPELSRDEREALLVQNFE 86
Cdd:PRK08025    5 QKFSREFLHPRYWLTWFGLGVLWLLVQLPYPVLCFLGTRIGRMSRPFLKRRESIARKNLELCFPQMSAEEREKMIAENFR 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280  87 SVGCAIFEVGMAWFWPDWRMRRLMKVEGEEHVINAMEKGQGMLLLSCHFLTLELNARCFGLVRPGVGVYRPNTNPVLEYA 166
Cdd:PRK08025   85 SLGMALLETGMAWFWPDSRVRKWFDVEGLDNLKRAQMQNRGVMVVGVHFMSLELGGRVMGLCQPMMATYRPHNNKLMEWV 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280 167 QYHGRCASNKYLVDRMDVKGMIKALRNGDALWYAPDHDYGSHASVFVPYFAVEQAATITGTATLARVKNTVTLPCYNIRT 246
Cdd:PRK08025  165 QTRGRMRSNKAMIGRNNLRGIVGALKKGEAVWFAPDQDYGPKGSSFAPFFAVENVATTNGTYVLSRLSGAAMLTVTMVRK 244

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2067289280 247 RE--GYTLHIGAPLADYPSgDDMADASRANREIEAAVRKAPEQYMWLHRRFKTRP 299
Cdd:PRK08025  245 ADysGYRLFITPEMEGYPT-DENQAAAYMNKIIEKEIMRAPEQYLWIHRRFKTRP 298
LpxP COG1560
Palmitoleoyl-ACP: Kdo2-lipid-IV acyltransferase (lipid A biosynthesis) [Lipid transport and ...
 35-295 2.08e-98

Palmitoleoyl-ACP: Kdo2-lipid-IV acyltransferase (lipid A biosynthesis) [Lipid transport and metabolism]; Palmitoleoyl-ACP: Kdo2-lipid-IV acyltransferase (lipid A biosynthesis) is part of the Pathway/BioSystem: Lipid A biosynthesis


Pssm-ID: 441168 [Multi-domain]  Cd Length: 271  Bit Score: 290.55  E-value: 2.08e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280  35 PWRSQMWLGRQLGTLARKLLKSRVKIARRNLELAMPELSRDEREALLVQNFESVGCAIFEVGMAWFWPDWRMRRLMKVEG 114
Cdd:COG1560     9 PLRLLYRLGDLLGRLLYRLAGRRRRVARRNLALAFPELSEAEREALARASFRNLGRTLLETLRLWRLSPERLRKRVEVEG 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280 115 EEHVINAMEKGQGMLLLSCHFLTLELNARCFGLV-RPGVGVYRPNTNPVLEYAQYHGRCASNKYLVDRMD-VKGMIKALR 192
Cdd:COG1560    89 LEHLEAALAEGRGVILLTPHFGNWELAGAALALRgYPVTAVYRPLKNPLLDRLIRRGRERFGGELIPRKDgVRALLRALR 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280 193 NGDALWYAPDHDYGSHASVFVPYFAVEqAATITGTATLARVKNTVTLPCYNIRTREG--YTLHIGAPLADyPSGDDMADA 270
Cdd:COG1560   169 KGGIVGLLPDQDPGRKSGVFVPFFGVP-AATPTGPARLARRTGAPVVPVFARRLPDGrgYRLEIEPPLED-FSEDVEADT 246

                         250       260
                  ....*....|....*....|....*
gi 2067289280 271 SRANREIEAAVRKAPEQYMWLHRRF 295
Cdd:COG1560   247 QRLNRALEAWIREHPEQWLWLHRRW 271
PRK05646 PRK05646
lipid A biosynthesis lauroyl acyltransferase; Provisional
 7-307 2.36e-98

lipid A biosynthesis lauroyl acyltransferase; Provisional


Pssm-ID: 235543 [Multi-domain]  Cd Length: 310  Bit Score: 291.72  E-value: 2.36e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280   7 PRLEPRLFHPRYWGSWLGLSLLWLLVLLPWRSQMWLGRQLGTLARKLLKSRVKIARRNLELAMPELSRDEREALLVQNFE 86
Cdd:PRK05646    4 PRFRAAFLHPRFWPLWLGLGLLWLVVQLPYRVLLWLGRALGALMYRLAGSRRRIAARNLELCFPEKSAAERERLLKENFA 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280  87 SVGCAIFEVGMAWFWPDWRMRRLMKVEGEEHVINAMEKGQGMLLLSCHFLTLELNARCFGLVRPGVGVYRPNTNPVLEYA 166
Cdd:PRK05646   84 STGIAFFEMAMSWWWPKARLARLAHIEGLEHLQQAQQEGQGVILMALHFTTLEIGAALLGQQHTIDGMYREHKNPVFDFI 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280 167 QYHGRCASNK--YLVDRMDVKGMIKALRNGDALWYAPDHDYGSHASVFVPYFAVeQAATITGTATLARVKNTVTLPCYNI 244
Cdd:PRK05646  164 QRRGRERHNLdsTAIEREDVRGMLKLLRAGRAIWYAPDQDYGAKQSIFVPLFGI-PAATVTATTKFARLGRARVIPFTQK 242

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2067289280 245 RTRE--GYTLHIGAPLADYPSGDDMADASRANREIEAAVRKAPEQYMWLHRRFKTRPnPDDPGYY 307
Cdd:PRK05646  243 RLADgsGYRLVIHPPLEDFPGESEEADCLRINQWVERVVRECPEQYLWAHRRFKSRP-EGEPKLY 306
Lip_A_acyltrans pfam03279
Bacterial lipid A biosynthesis acyltransferase;
7-297 3.53e-78

Bacterial lipid A biosynthesis acyltransferase;


Pssm-ID: 281296 [Multi-domain]  Cd Length: 294  Bit Score: 239.94  E-value: 3.53e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280   7 PRLEPRLFHPRYWGSWLGLSLLWLLVLLPWRSQMWLGRQLGTLARKLLKSRVKIARRNLELAMPELSRDEREALLVQNFE 86
Cdd:pfam03279   1 PKFSPELLHPRYWLDWLGIAVLRLLALLPYSALRRIGKGLGRLAGRFLKRRRKIARRNLALCFPEMSEAEREQIIDKSFA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280  87 SVGCAIFEVGMAWFWPDWRMRRLMKVEGEEHVINAMEKGQGMLLLSCHFLTLELNARCFGLVRPGVGVYRPNT-NPVLEY 165
Cdd:pfam03279  81 SVGRAIVETGRVWFWPDSRIAKRFEVIGLEHIKEALAQGRGAILVGPHFGNWDLGGRVLGQQYPGMAVYRPNLkNPLLDW 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280 166 AQYHGRCASNKYLVDRMD-VKGMIKALRNGDALWYAPDHDYGSHASVFVPYFAVEQAATiTGTATLARVKNTVTLPCYNI 244
Cdd:pfam03279 161 LQTSGRERFGGRMLPRQNgIKGLIKALRKGEVVWYLPDQDLGRKDSVFVPFFGVPAATT-TGPAKLALKTKAAVIPVFPI 239

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2067289280 245 RTREG--YTLHIGAPLADYPSGDDMADASRANREIEAAVRKAPEQYMWLHRRFKT 297
Cdd:pfam03279 240 RNGDGsgYTVIVHPALDLTITDDVEQIAQAMNQIVEKFIMPAPEQYFWLHRRWKT 294
PRK08733 PRK08733
LpxL/LpxP family Kdo(2)-lipid IV(A) lauroyl/palmitoleoyl acyltransferase;
1-299 1.60e-68

LpxL/LpxP family Kdo(2)-lipid IV(A) lauroyl/palmitoleoyl acyltransferase;


Pssm-ID: 181542 [Multi-domain]  Cd Length: 306  Bit Score: 215.54  E-value: 1.60e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280   1 MAQEHAPRLEPRLFHPRYWGSWLGLSLLWLLVLLPWRSQMWLGRQLGTLARKLLKSRVKIARRNLELAMPELSRDEREAL 80
Cdd:PRK08733    1 MSESANVAVRPSLRNPKHWPMYLGLAVMVLAARLPWTLQRALGRGVGWVAMRLAGTRRRAAEVNLKLCFPEQDDAWRARL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280  81 LVQNFESVGCAIFEVGMAWFWPDWRMRRLMKVEGEEHVINAMEKGQGMLLLSCHFLTLELNARCFGLVRPGVGVYRPNTN 160
Cdd:PRK08733   81 LRDSFDALGVGLFEFARAWWGSIDVIRPGVQIEGLEHLQQLQQQGRGVLLVSGHFMTLEMCGRLLCDHVPLAGMYRRHRN 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280 161 PVLEYAQYHGRCASNKYLVDRMDVKGMIKALRNGDALWYAPDHDYGSHASVFVPYFAVEqAATITGTATLARVKNTVTLP 240
Cdd:PRK08733  161 PVFEWAVKRGRLRYATHMFANEDLRATIKHLKRGGFLWYAPDQDMRGKDTVFVPFFGHP-ASTITATHQLARLTGCAVVP 239

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2067289280 241 CYNIRTREGYTLHIGAPLADYPSGDDMADASRANREIEAAVRKAPEQYMWLHRRFKTRP 299
Cdd:PRK08733  240 YFHRREGGRYVLKIAPPLADFPSDDVIADTTRVNAAIEDMVREAPDQYLWIHRRFKRQP 298
LPLAT_LABLAT-like cd07984
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; ...
 107-296 5.06e-64

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as lipid A biosynthesis lauroyl/myristoyl (LABLAT, HtrB) acyltransferases and similar proteins.


Pssm-ID: 153246 [Multi-domain]  Cd Length: 192  Bit Score: 200.13  E-value: 5.06e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280 107 RRLMKVEGEEHVINAMEKGQGMLLLSCHFLTLELNARCFGL-VRPGVGVYRPNTNPVLEYAQYHGRCASNKYLVDR-MDV 184
Cdd:cd07984     1 LKRVEREGLEHLEAALAKGKGVILLTAHFGNWELAGLALALlGYPVTVVYRPLKNPLLDRLITRGRERFGARLIPRgGGL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280 185 KGMIKALRNGDALWYAPDHDYGSHASVFVPyFAVEQAATITGTATLARVKNTVTLPCYNIRT-REGYTLHIGAPLADYPS 263
Cdd:cd07984    81 RELIRALKKGEIVGILPDQDPGRKGGVFVP-FFGRPAATPTGPARLALKTGAPVVPAFAYRLpGGGYRIEFEPPLENPPS 159

                         170       180       190
                  ....*....|....*....|....*....|...
gi 2067289280 264 GDDMADASRANREIEAAVRKAPEQYMWLHRRFK 296
Cdd:cd07984   160 EDVEEDTQRLNDALEAAIREHPEQWLWFHRRWK 192
PRK08706 PRK08706
lipid A biosynthesis lauroyl acyltransferase; Provisional
 33-306 9.36e-52

lipid A biosynthesis lauroyl acyltransferase; Provisional


Pssm-ID: 169557 [Multi-domain]  Cd Length: 289  Bit Score: 171.97  E-value: 9.36e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280  33 LLPWRSQMWLGRQLGTLARKLLKSRVKIARRNLELAMPELSRDEREALLVQNFESVGCAIFEVGMAWFWPDWRMRRLMKV 112
Cdd:PRK08706   13 FLPFALLHKLADLTGLLAYLLVKPRRRIGEINLAKCFPEWDEEKRKTVLKQHFKHMAKLMLEYGLYWYAPAGRLKSLVRY 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280 113 EGEEHVINAMEKGQGMLLLSCHFLTLELNARCFGLVRPGVGVYRPNTNPVLEYAQYHGRCA-SNKYLVDRMD-VKGMIKA 190
Cdd:PRK08706   93 RNKHYLDDALAAGEKVIILYPHFTAFEMAVYALNQDVPLISMYSHQKNKILDEQILKGRNRyHNVFLIGRTEgLRALVKQ 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280 191 LRNGDA-LWYAPDHDYGSHASVFVPYFAVeQAATITGTATLARVKNTVTLPCYNIRTREG-YTLHIGAPLADYPSGDDMA 268
Cdd:PRK08706  173 FRKSSApFLYLPDQDFGRNDSVFVDFFGI-QTATITGLSRIAALANAKVIPAIPVREADNtVTLHFYPAWDSFPSEDAQA 251

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 2067289280 269 DASRANREIEAAVRKAPEQYMWLHRRFKTRPNPDDPGY 306
Cdd:PRK08706  252 DAQRMNRFIEERVREHPEQYFWLHKRFKTRPEGSPDFY 289
PRK08943 PRK08943
lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; Validated
 4-303 1.06e-48

lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; Validated


Pssm-ID: 236355  Cd Length: 314  Bit Score: 164.66  E-value: 1.06e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280   4 EHAPRLEPRLFHPRYWGSWLGLSLLWLLVLLPWRSQMWLGRQLGTLARKLLKSRVKIARRNLELAMPELSRDEREALLVQ 83
Cdd:PRK08943    9 EYIPRFQKSFLHPRYWGTWLGIGALAGLALMPPRLRDPLAAKLGRLVGKLAKKARRRARINLSLCFPEKSEAEREAIIDE 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280  84 NFESVGCAIFEVG-MAWFWPDWRMRRlMKVEGEEHVINAMEKGQGMLLLSCH-----FLTLELNARcfGLvrPGVGVYRP 157
Cdd:PRK08943   89 MFATAPQAMLMMAeLALRSPKHLQRR-VEWHGLEILEEARANGENVIFLVPHgwaidIPAMLLASQ--GQ--PMAAMFHN 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280 158 NTNPVLEY------AQYHGRcasnkyLVDRMD-VKGMIKALRNGDALWYAPDHDYGSHASVFVPYFAVEQaATITGTATL 230
Cdd:PRK08943  164 QRNPLFDWlwnrvrRRFGGR------LHAREDgIKPFISSVRQGYWGYYLPDEDHGPEHSVFVDFFATYK-ATLPGIGRL 236

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2067289280 231 ARVKNTVTLPC---YNIRTREgYTLHIGAPLADYPSGDDMADASRANREIEAAVRKAPEQYMWLHRRFKTRPNPDD 303
Cdd:PRK08943  237 AKVCRARVVPLfpvYNGKTHR-LDIEIRPPMDDLLSADDETIARRMNEEVEQFVGPHPEQYMWILKLLKTRKPGED 311
PRK06946 PRK06946
lipid A biosynthesis lauroyl acyltransferase; Provisional
 42-307 7.91e-48

lipid A biosynthesis lauroyl acyltransferase; Provisional


Pssm-ID: 180770 [Multi-domain]  Cd Length: 293  Bit Score: 161.77  E-value: 7.91e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280  42 LGRQLGTLARKLLKSRVKIARRNLELAMPELSRDEREALLVQNFESVGCAIFEVGMAWFWPDWRMRRLMKVEGEEHVINA 121
Cdd:PRK06946   27 FGDGLGWLLYRIPSRRRRIVHTNLKLCFPDWSDARREELARRHFRHVIRSYVERSVQWFGSEKKLEKLVQVDSAIDLTDP 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280 122 meKGQGMLLLSCHFLTLELNA--RCFGLVRPGVGVYRPNTNPVLEYAQYHGRCASNKYLVDRMD-VKGMIKALRNGDALW 198
Cdd:PRK06946  107 --DGPPTIFLGLHFVGIEAGSiwLNYSLRRRVGSLYTPMSNPLLDAIAKAARGRFGAEMVSRADsARQVLRWLRDGKPVM 184

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280 199 YAPDHDYGSHASVFVPYFAVeQAATITGTATLARVKNTVTLPCYN--IRTREGYTLHIGAPLADYPSGDDMADASRANRE 276
Cdd:PRK06946  185 LGADMDFGLRDSTFVPFFGV-PACTLTAVSRLARTGGAQVVPFITevLPDYKGYRLRVFKPWENYPTGDDDLDARRMNAF 263

                         250       260       270
                  ....*....|....*....|....*....|.
gi 2067289280 277 IEAAVRKAPEQYMWLHRRFKTRPnPDDPGYY 307
Cdd:PRK06946  264 LEEQIRLMPEQYYWVHKRFKTRP-PGEPSVY 293
lipid_A_msbB TIGR02208
lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; This family consists of MsbB ...
 7-299 4.86e-41

lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; This family consists of MsbB in E. coli and closely related proteins in other species. MsbB is homologous to HtrB (TIGR02207) and acts immediately after it in the biosynthesis of KDO-2 lipid A (also called Re LPS and Re endotoxin). These two enzymes act after creation of KDO-2 lipid IV-A by addition of the KDO sugars. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 274032  Cd Length: 305  Bit Score: 144.56  E-value: 4.86e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280   7 PRLEPRLFHPRYWGSWLGLSLLWLLVLLPWRSQMWLGRQLGTLARKLLKSRVKIARRNLELAMPELSRDEREALLVQNFE 86
Cdd:TIGR02208   3 RRFQKSFLHPKYWGTWLGVFALVLLAFMPAKLRDPIAKVLAKFVGPIAKKPRGRARINLSACFPEKSEAERETIIDNNFA 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280  87 SVGCAIFEVGMAWFWPDWRMRRLMKVEGEEHVINAMEKGQGMLLLSCHFLTLELNA-RCFGLVRPGVGVYRPNTNPVLEY 165
Cdd:TIGR02208  83 TFVQVMLSQAELAIRSKAHLRRRVNLMGLEHIEAAQAAGKPVIFLVPHGWAIDYAGlRLASQGLPMVTMFNNHKNPLFDW 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280 166 AQYHGRCASNKYLVDRMD-VKGMIKALRNGDALWYAPDHDYGSHASVFVPYFAVeQAATITGTATLARVKNTVTLPC--- 241
Cdd:TIGR02208 163 LWNRVRSRFGGHVYAREAgIKALLASLKRGESGYYLPDEDHGPEQSVFVPFFAT-YKATLPVVGRLAKAGNAQVVPVfpg 241

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2067289280 242 YNIRTREgYTLHIGAPLADYPSGDDMADASRANREIEAAVRKAPEQYMWLHRRFKTRP 299
Cdd:TIGR02208 242 YNQVTGK-FELTVRPAMATELSVDPEQEARAMNKEVEQFILPYPEQYMWILRLLKTRP 298
PRK08905 PRK08905
lysophospholipid acyltransferase family protein;
42-304 4.08e-30

lysophospholipid acyltransferase family protein;


Pssm-ID: 236348 [Multi-domain]  Cd Length: 289  Bit Score: 115.09  E-value: 4.08e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280  42 LGRQLGTLARKLLKSRVKIARRNLELAMPelsrDEREALLVQNFESVGCAIFEvgMAWFW---PDWRMRRLMKVEGEEHV 118
Cdd:PRK08905   20 LGGWLGRLAYRLPGRYRRRLRANLRQAGG----DPDPAMVKAAAAETGRMILE--LPYVWfrkPEEIETMVKDDHGWEHV 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280 119 INAMEKGQGMLLLSCHFLTLELNARCFGLVRPGVGVYRPNTNPVLEYAQYHGRCASNKYLV--DRMDVKGMIKALRNGDA 196
Cdd:PRK08905   94 EAALAEGRGILFLTPHLGCFEVTARYIAQRFPLTAMFRPPRKAALRPLMEAGRARGNMRTApaTPQGVRMLVKALRRGEA 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280 197 LWYAPDHDYGSHASVFVPYFAvEQAATITGTATLARVKNTVTLPCYNIRTR--EGYTLHIgAPLADYPSGDDMADASRAN 274
Cdd:PRK08905  174 VGILPDQVPSGGEGVWAPFFG-RPAYTMTLVARLAEVTGVPVIFVAGERLPrgRGYRLHL-RPVQEPLPGDKAADAAVIN 251

                         250       260       270
                  ....*....|....*....|....*....|
gi 2067289280 275 REIEAAVRKAPEQYMWLHRRFKTRPNPDDP 304
Cdd:PRK08905  252 AEIERLIRRFPTQYLWGYNRYKRPRGAPAP 281
PRK05645 PRK05645
lysophospholipid acyltransferase;
35-307 3.41e-24

lysophospholipid acyltransferase;


Pssm-ID: 135493 [Multi-domain]  Cd Length: 295  Bit Score: 99.59  E-value: 3.41e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280  35 PWRSQMWLGRQLGTLARKLLKSRVKIARRNLELAMPELSRDEREALLVQNFESVGCAIFEVGMAWFWPDWRMRRLMK-VE 113
Cdd:PRK05645   20 PWRAVQGVGAGIGWLMWKLPNRSREVVRINLSKCFPELSPAELEKLVGQSLMDIGKTLTESACAWIWPPQKSLELVReVE 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280 114 GEEHVINAMEKGQGMLLLSCHFLTLE-LNARCFGLVRPgVGVYRPntnPVL---------EYAQYHGRCASNKylvdRMD 183
Cdd:PRK05645  100 GLEVLEQALASGKGVVGITSHLGNWEvLNHFYCSQCKP-IIFYRP---PKLkavdellrkQRVQLGNRVAPST----KEG 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280 184 VKGMIKALRNGDALWYAPDHDYGSHASVFVPYFAVEQAATITGTATLARVKNT-VTLPCYNIRTREGYTLHIGAPLADYP 262
Cdd:PRK05645  172 ILSVIKEVRKGGQVGIPADPEPAESAGIFVPFLGTQALTSKFVPNMLAGGKAVgVFLHALRLPDGSGYKVILEAAPEDMY 251

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 2067289280 263 SGDDMADASRANREIEAAVRKAPEQYMWLHRRFKTRPnPDDPGYY 307
Cdd:PRK05645  252 STDVEVSAAAMSKVVERYVRAYPSQYMWSMKRFKKRP-AGEARWY 295
PRK08734 PRK08734
lauroyl acyltransferase;
35-307 7.68e-24

lauroyl acyltransferase;


Pssm-ID: 181543 [Multi-domain]  Cd Length: 305  Bit Score: 98.80  E-value: 7.68e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280  35 PWRSQMWLGRQLGTLARKLLKSRVKIARRNLELAMPELSRDEREALLVQNFESVGCAIFEVGMAWFWPDWR-MRRLMKVE 113
Cdd:PRK08734   21 PWPLLKRLADLLAWSWRKLNARESRVTRRNLELAYPELSPQQRAQLHAQILRSTARQALEVLRTWTHPPAEnLARLRQRH 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280 114 GEEHVINAMEKGQGMLLLSCHFLTLELNARCFGLVRPGVGVYRPNTNPVLEYAQYHGRCASNKYLV--DRMDVKGMIKAL 191
Cdd:PRK08734  101 GQELYDAALASGRGVIVAAPHFGNWELLNQWLSERGPIAIVYRPPESEAVDGFLQLVRGGDNVRQVraEGPAVRQLFKVL 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280 192 RNGDALWYAPDHDYGSHASVFVPYFAVeQAATITGTATLARVKNTVTLP--CYNIRTREGYTLHIGAPLADYPSGDDMAD 269
Cdd:PRK08734  181 KDGGAVGILPDQQPKMGDGVFAPFFGI-PALTMTLVNRLAERTGATVLYgwCERIGPDLEFALHVQPADPAVADPDPLRA 259

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 2067289280 270 ASRANREIEAAVRKAPEQYMWLHRRFKTR-PNPDDPGYY 307
Cdd:PRK08734  260 ATALNAGIERIARRDPAQYQWTYKRYTLRpPGSGEHNPY 298
PRK08419 PRK08419
lipid A biosynthesis lauroyl acyltransferase; Reviewed
 46-296 1.35e-16

lipid A biosynthesis lauroyl acyltransferase; Reviewed


Pssm-ID: 181420 [Multi-domain]  Cd Length: 298  Bit Score: 78.53  E-value: 1.35e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280  46 LGTLARKLLKSRVKIARRNLELAMPE-LSRDEREALLVQNFESVGCAIFEVGMAWFWPDWRMRRLMKVEGEEHVINAMEK 124
Cdd:PRK08419   32 LAFIMRYLDKKRRKIAKANLDFCFGEsKSQEEKKRIIKKCYENFAFFGLDFIRNQNTTKEEILNKVTFINEENLLDALKK 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280 125 GQGMLLLSCHFLTLELNARCFGLVRPGVG-VYRPNTNPVLEYAQYHGRCASNKYLVDRMDV-KGMIKALRNGDALWYAPD 202
Cdd:PRK08419  112 KRPIIVTTAHYGYWELFSLALAAYYGAVSiVGRLLKSAPINEMISKRREQFGIELIDKKGAmKELLKALKQGRALGILVD 191

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280 203 HDYGSHASVFVPYFAvEQAATITGTATLARVKNTVTLPCYNIRTREG-YTLHIGAPLADYPSGDDMADASRANRE----I 277
Cdd:PRK08419  192 QNVVPKEGVEVKFFN-KRVTHTTIASILARRYNALIIPVFIFNDDYShFTITFFPPIRSKITDDAEADILEATQAqasaC 270

                         250
                  ....*....|....*....
gi 2067289280 278 EAAVRKAPEQYMWLHRRFK 296
Cdd:PRK08419  271 EEMIRKKPDEYFWFHRRFK 289
PRK06628 PRK06628
lipid A biosynthesis lauroyl acyltransferase; Provisional
 49-296 1.50e-08

lipid A biosynthesis lauroyl acyltransferase; Provisional


Pssm-ID: 102471  Cd Length: 290  Bit Score: 54.94  E-value: 1.50e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280  49 LARK--LLKSRVKIARRNLELAMPELSrdEREALLVQNFESVGCAIFEVGMAWFWPDWRMRRLMKVEGEEHVINAmeKGQ 126
Cdd:PRK06628   39 IARKvgILFAVNKIARRNIKAVFGDMC--DVEKIIDQTWDNFGRFIGEFTYVNKMDEAELERRIEIIGIENIKKL--EGQ 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280 127 GMLLLSCHFLTLELNARCFGLVRPGVGV-YRPNTNPVLEYAQYHGRCASNKYLVDR--MDVKGMIKALRNGDALWYAPDH 203
Cdd:PRK06628  115 PFLLFSGHFANWDISLKILHKFYPKVAViYRKANNPYVNKLVNESRAGDKLRLIPKgpEGSRALVRAIKESESIVMLVDQ 194

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280 204 DYGShaSVFVPYFAvEQAATITGTATLARVKNTVTLPCYNIRTREGYTLHIGAPLADYP-SGDDMADASRA----NREIE 278
Cdd:PRK06628  195 KMND--GIEVPFLG-HPAMTASAIAKIALQYKYPIIPCQIIRTKGSYFKVIVHPQLKFEqTGDNKADCYNImlniNQMLG 271

                         250
                  ....*....|....*...
gi 2067289280 279 AAVRKAPEQYMWLHRRFK 296
Cdd:PRK06628  272 EWVKQNPAQWFWFHNRWK 289
PRK06553 PRK06553
lipid A biosynthesis lauroyl acyltransferase; Provisional
 47-294 2.90e-07

lipid A biosynthesis lauroyl acyltransferase; Provisional


Pssm-ID: 235827 [Multi-domain]  Cd Length: 308  Bit Score: 51.13  E-value: 2.90e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280  47 GTLARKL--LKSRVKIARRNLELAMPELSRDEREALLVQNFESVGCAIFE-VGMAWFW---PDWRMRRLMKVEGEEHVIN 120
Cdd:PRK06553   48 GRLARLIgpLLPRHRVALDNLRAAFPEKSEAEIEAIALGMWDNLGRLGAEyAFLDAIFdydPEAPEPGRVEVRGIEIFER 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280 121 AMEKGQGMLLLSCHFLTLELNARC---FGLvrPGVGVYRPNTNPVLEYAQYHGRCASNKYLV--DRMDVKGMIKALRNGD 195
Cdd:PRK06553  128 LRDDGKPALIFTAHLGNWELLAIAaaaFGL--DVTVLFRPPNNPYAARKVLEARRTTMGGLVpsGAGAAFALAGVLERGG 205

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280 196 ALWYAPDHDYGShaSVFVPYFAVEQAATITgTATLARVKN-------TVTLPcyNIRTREGYTLHIGAPLADYPSGDDMA 268
Cdd:PRK06553  206 HVGMLVDQKFTR--GVEVTFFGRPVKTNPL-LAKLARQYDcpvhgarCIRLP--GGRFRLELTERVELPRDADGQIDVQA 280

                         250       260
                  ....*....|....*....|....*.
gi 2067289280 269 DASRANREIEAAVRKAPEQYMWLHRR 294
Cdd:PRK06553  281 TMQALTDVVEGWVREYPGQWLWLHRR 306
PRK05906 PRK05906
lipid A biosynthesis lauroyl acyltransferase; Provisional
 42-296 8.10e-04

lipid A biosynthesis lauroyl acyltransferase; Provisional


Pssm-ID: 168292 [Multi-domain]  Cd Length: 454  Bit Score: 40.92  E-value: 8.10e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280  42 LGRQLGTLARKLLKSRVKIARRNLELAMPELSRDER----------------EALLVQNF-----ESVGCAIFEVGMAWF 100
Cdd:PRK05906   39 FGKGLGTLLFYFISDYRKTALTNLALAFPEKSFAERyqiarqsvqhviitflELLAVEKLaghidELIAIATSEDAPEGF 118

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280 101 WPDwrmrRLMKVEGEEHVINAMEKGQGMLLLSCHFLTLELNARCFGLVRPGVGVYRPNTNPVLEYAQYHGR-CASNKYLV 179
Cdd:PRK05906  119 FPE----EVSSQQELEHTFSRLDEQEGAILFCGHQANWELPFLYITKRYPGLAFAKPIKNRRLNKKIFSLReSFKGKIVP 194

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2067289280 180 DRMDVKGMIKALRNGDALWYAPDHDYGShASVFVPYFAvEQAATITGTATLArVKNTVTLPCYNI-RTREGYTLhigapl 258
Cdd:PRK05906  195 PKNGINQALRALHQGEVVGIVGDQALLS-SSYSYPLFG-SQAFTTTSPALLA-YKTGKPVIAVAIyRKPNGYLV------ 265

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 2067289280 259 adYPSGDDMADASRANRE------------IEAAVRKAPEQYMWLHRRFK 296
Cdd:PRK05906  266 --VPSKKFYANKSLPIKEsteqlmdrlmrfLEKGIACKPEQWMWLHKRWK 313
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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