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Conserved domains on  [gi|2067347974|dbj|GJA50341|]
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hypothetical protein KAM347_21320 [Aeromonas caviae]

Protein Classification

Sec-independent protein translocase family protein( domain architecture ID 241)

Sec-independent protein translocase family protein such as Sec-independent protein translocase proteins TatA and TatB, which are part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes

Gene Ontology:  GO:0033281|GO:0043953

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TatA_B_E super family cl00788
mttA/Hcf106 family; Members of this protein family are involved in a sec independent ...
 3-49 6.79e-08

mttA/Hcf106 family; Members of this protein family are involved in a sec independent translocation mechanism. This pathway has been called the DeltapH pathway in chloroplasts. Members of this family in E.coli are involved in export of redox proteins with a "twin arginine" leader motif.


The actual alignment was detected with superfamily member PRK04598:

Pssm-ID: 445098  Cd Length: 81  Bit Score: 44.08  E-value: 6.79e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 2067347974  3 LGGIHIWHLLILLVVVVVVFGSKRLAGAGEDLGTAIRDFRNALRDDD 49
Cdd:PRK04598   1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGSDLGSAVKGFKKAMSEEE 47
 
Name Accession Description Interval E-value
tatA PRK04598
twin-arginine translocase subunit TatA;
3-49 6.79e-08

twin-arginine translocase subunit TatA;


Pssm-ID: 179867  Cd Length: 81  Bit Score: 44.08  E-value: 6.79e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 2067347974  3 LGGIHIWHLLILLVVVVVVFGSKRLAGAGEDLGTAIRDFRNALRDDD 49
Cdd:PRK04598   1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGSDLGSAVKGFKKAMSEEE 47
tatAE TIGR01411
twin arginine-targeting protein translocase, TatA/E family; This model distinguishes TatA/E ...
 5-50 3.98e-05

twin arginine-targeting protein translocase, TatA/E family; This model distinguishes TatA/E from the related TatB, but does not distinguish TatA from TatE. The Tat (twin-arginine translocation) system is a Sec-independent exporter for folded proteins, often with a redox cofactor already bound, across the bacterial inner membrane. Functionally equivalent systems are found in the chloroplast and some in archaeal species. The signal peptide recognized by the Tat system is modeled by TIGR01409. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273605 [Multi-domain]  Cd Length: 47  Bit Score: 36.05  E-value: 3.98e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 2067347974  5 GIHIWHLLILLVVVVVVFGSKRLAGAGEDLGTAIRDFRNALRDDDN 50
Cdd:TIGR01411  1 GLSPPEWLIILVVILLLFGAKKLPELGRDLGKAIKEFKKALKEEED 46
TatA COG1826
Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, ...
 22-50 4.56e-04

Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 441431 [Multi-domain]  Cd Length: 72  Bit Score: 34.14  E-value: 4.56e-04
                         10        20
                 ....*....|....*....|....*....
gi 2067347974 22 FGSKRLAGAGEDLGTAIRDFRNALRDDDN 50
Cdd:COG1826   20 FGPKKLPELARSLGKAIREFKKAANEVKE 48
TatA_B_E pfam02416
mttA/Hcf106 family; Members of this protein family are involved in a sec independent ...
 6-50 1.80e-03

mttA/Hcf106 family; Members of this protein family are involved in a sec independent translocation mechanism. This pathway has been called the DeltapH pathway in chloroplasts. Members of this family in E.coli are involved in export of redox proteins with a "twin arginine" leader motif.


Pssm-ID: 426762  Cd Length: 53  Bit Score: 31.89  E-value: 1.80e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 2067347974  6 IHIWHLLILLVVVVVVFGSKRLAGAGEDLGTAIRDFRNALRDDDN 50
Cdd:pfam02416  1 LGIPELLIILVVALLLFGPKKLPELGRALGKTLREFKKATKELEE 45
 
Name Accession Description Interval E-value
tatA PRK04598
twin-arginine translocase subunit TatA;
3-49 6.79e-08

twin-arginine translocase subunit TatA;


Pssm-ID: 179867  Cd Length: 81  Bit Score: 44.08  E-value: 6.79e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 2067347974  3 LGGIHIWHLLILLVVVVVVFGSKRLAGAGEDLGTAIRDFRNALRDDD 49
Cdd:PRK04598   1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGSDLGSAVKGFKKAMSEEE 47
tatA PRK04561
twin arginine translocase protein A; Provisional
 3-49 1.82e-07

twin arginine translocase protein A; Provisional


Pssm-ID: 179864  Cd Length: 75  Bit Score: 42.59  E-value: 1.82e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 2067347974  3 LGGIHIWHLLILLVVVVVVFGSKRLAGAGEDLGTAIRDFRNALRDDD 49
Cdd:PRK04561   1 MGSFSIWHWLVVLVIVLLVFGTKRLTSGAKDLGSAVKEFKKGMHDDD 47
tatA PRK03554
Sec-independent protein translocase subunit TatA;
3-54 2.32e-07

Sec-independent protein translocase subunit TatA;


Pssm-ID: 179592  Cd Length: 89  Bit Score: 42.74  E-value: 2.32e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 2067347974  3 LGGIHIWHLLILLVVVVVVFGSKRLAGAGEDLGTAIRDFRNALRDDDNIRNK 54
Cdd:PRK03554   1 MGGISIWQLLIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMSDDEPKQDK 52
tatA PRK01833
Sec-independent protein translocase subunit TatA;
3-48 1.18e-05

Sec-independent protein translocase subunit TatA;


Pssm-ID: 167284  Cd Length: 74  Bit Score: 38.32  E-value: 1.18e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 2067347974  3 LGGIHIWHLLILLVVVVVVFGSKRLAGAGEDLGTAIRDFRNALRDD 48
Cdd:PRK01833   1 MGGISIWQLLIIVAIIVLLFGTKKLRTLGTDLGESVKGFKKAMADD 46
tatA PRK00442
twin-arginine translocase TatA/TatE family subunit;
21-49 1.25e-05

twin-arginine translocase TatA/TatE family subunit;


Pssm-ID: 234764  Cd Length: 92  Bit Score: 38.32  E-value: 1.25e-05
                         10        20
                 ....*....|....*....|....*....
gi 2067347974 21 VFGSKRLAGAGEDLGTAIRDFRNALRDDD 49
Cdd:PRK00442  19 VFGTKKLKNLGSDVGESIKGFRKAMNEDE 47
tatAE TIGR01411
twin arginine-targeting protein translocase, TatA/E family; This model distinguishes TatA/E ...
 5-50 3.98e-05

twin arginine-targeting protein translocase, TatA/E family; This model distinguishes TatA/E from the related TatB, but does not distinguish TatA from TatE. The Tat (twin-arginine translocation) system is a Sec-independent exporter for folded proteins, often with a redox cofactor already bound, across the bacterial inner membrane. Functionally equivalent systems are found in the chloroplast and some in archaeal species. The signal peptide recognized by the Tat system is modeled by TIGR01409. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273605 [Multi-domain]  Cd Length: 47  Bit Score: 36.05  E-value: 3.98e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 2067347974  5 GIHIWHLLILLVVVVVVFGSKRLAGAGEDLGTAIRDFRNALRDDDN 50
Cdd:TIGR01411  1 GLSPPEWLIILVVILLLFGAKKLPELGRDLGKAIKEFKKALKEEED 46
tatE PRK03625
twin-arginine translocase subunit TatE;
22-49 7.92e-05

twin-arginine translocase subunit TatE;


Pssm-ID: 179612  Cd Length: 67  Bit Score: 35.90  E-value: 7.92e-05
                         10        20
                 ....*....|....*....|....*...
gi 2067347974 22 FGSKRLAGAGEDLGTAIRDFRNALRDDD 49
Cdd:PRK03625  20 FGTKKLRTLGGDLGAAIKGFKKAMNDDD 47
TatA COG1826
Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, ...
 22-50 4.56e-04

Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 441431 [Multi-domain]  Cd Length: 72  Bit Score: 34.14  E-value: 4.56e-04
                         10        20
                 ....*....|....*....|....*....
gi 2067347974 22 FGSKRLAGAGEDLGTAIRDFRNALRDDDN 50
Cdd:COG1826   20 FGPKKLPELARSLGKAIREFKKAANEVKE 48
tatA PRK02958
Sec-independent protein translocase subunit TatA;
3-49 1.58e-03

Sec-independent protein translocase subunit TatA;


Pssm-ID: 235091  Cd Length: 73  Bit Score: 32.63  E-value: 1.58e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 2067347974  3 LGGIHIWHLLILLVVVVVVFGSKRLAGAGEDLGTAIRDFRNALRDDD 49
Cdd:PRK02958   1 MGSFSIWHWLIVLVIVVLVFGTKKLRNIGSDLGGAVKGFKDGMKEGE 47
TatA_B_E pfam02416
mttA/Hcf106 family; Members of this protein family are involved in a sec independent ...
 6-50 1.80e-03

mttA/Hcf106 family; Members of this protein family are involved in a sec independent translocation mechanism. This pathway has been called the DeltapH pathway in chloroplasts. Members of this family in E.coli are involved in export of redox proteins with a "twin arginine" leader motif.


Pssm-ID: 426762  Cd Length: 53  Bit Score: 31.89  E-value: 1.80e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 2067347974  6 IHIWHLLILLVVVVVVFGSKRLAGAGEDLGTAIRDFRNALRDDDN 50
Cdd:pfam02416  1 LGIPELLIILVVALLLFGPKKLPELGRALGKTLREFKKATKELEE 45
tatE PRK01614
Sec-independent protein translocase subunit TatA;
22-49 2.57e-03

Sec-independent protein translocase subunit TatA;


Pssm-ID: 234965  Cd Length: 85  Bit Score: 32.56  E-value: 2.57e-03
                         10        20
                 ....*....|....*....|....*...
gi 2067347974 22 FGSKRLAGAGEDLGTAIRDFRNALRDDD 49
Cdd:PRK01614  20 FGTSKLRTLGADLGAALKGFKKAMRNDD 47
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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