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Conserved domains on  [gi|2131487360|dbj|GJJ86932|]
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ligase [Enterobacter cloacae]

Protein Classification

O-antigen ligase family protein( domain architecture ID 11462199)

O-antigen ligase family protein may be involved in the synthesis of O-antigen, a lipopolysaccharide found in the outer membrane of gram-negative bacteria; similar to Escherichia coli O-antigen ligase RfaL, which adds the O-antigen on the glucose group of lipopolysaccharide

PubMed:  17890310

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
RfaL COG3307
O-antigen ligase [Cell wall/membrane/envelope biogenesis];
154-393 8.88e-21

O-antigen ligase [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442536 [Multi-domain]  Cd Length: 239  Bit Score: 90.53  E-value: 8.88e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2131487360 154 NRATVSAYVYSVLSLAFVYSLYLQQNVKLYVVAGFTILISYFVILLTGTRAAMGLYLLLAIVLTLYHFRKIHLKSALIFL 233
Cdd:COG3307     4 NPNHLAAYLALALPLLLALLLLLKRRRLRRLLALLALLLALLALLLTGSRGAWLALLVGLLLLLLLYKRKLRLRRLLLLL 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2131487360 234 CIVAGVVIVSYkPLISPKIQQTQREVERyqqgfDRTSLGARFSMWTIGIENGLAHP-LGQSLEEREAWTRHYIKDGHPHL 312
Cdd:COG3307    84 LAALLLLLLAL-ILVSPPLAERLLEILG-----KDSSLGGRLEIWKAALEMIKEHPlLGVGYGNFWYAYPAYQPAGYIWN 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2131487360 313 GsaleyikVHLHNEFIEKYSLQGIPGVAVMLFFFVSMIVYALRNRNALLLTSMLLLL-----LYGLTDVILLSSEALIFF 387
Cdd:COG3307   158 A-------GHAHNEYLEILAETGILGLLLLLLLLLVLLRRALRRLRRSRLALALLALllallVHGLTESPLFSPASALLF 230

                  ....*.
gi 2131487360 388 MILFAL 393
Cdd:COG3307   231 WLLLAL 236
 
Name Accession Description Interval E-value
RfaL COG3307
O-antigen ligase [Cell wall/membrane/envelope biogenesis];
154-393 8.88e-21

O-antigen ligase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442536 [Multi-domain]  Cd Length: 239  Bit Score: 90.53  E-value: 8.88e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2131487360 154 NRATVSAYVYSVLSLAFVYSLYLQQNVKLYVVAGFTILISYFVILLTGTRAAMGLYLLLAIVLTLYHFRKIHLKSALIFL 233
Cdd:COG3307     4 NPNHLAAYLALALPLLLALLLLLKRRRLRRLLALLALLLALLALLLTGSRGAWLALLVGLLLLLLLYKRKLRLRRLLLLL 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2131487360 234 CIVAGVVIVSYkPLISPKIQQTQREVERyqqgfDRTSLGARFSMWTIGIENGLAHP-LGQSLEEREAWTRHYIKDGHPHL 312
Cdd:COG3307    84 LAALLLLLLAL-ILVSPPLAERLLEILG-----KDSSLGGRLEIWKAALEMIKEHPlLGVGYGNFWYAYPAYQPAGYIWN 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2131487360 313 GsaleyikVHLHNEFIEKYSLQGIPGVAVMLFFFVSMIVYALRNRNALLLTSMLLLL-----LYGLTDVILLSSEALIFF 387
Cdd:COG3307   158 A-------GHAHNEYLEILAETGILGLLLLLLLLLVLLRRALRRLRRSRLALALLALllallVHGLTESPLFSPASALLF 230

                  ....*.
gi 2131487360 388 MILFAL 393
Cdd:COG3307   231 WLLLAL 236
Wzy_C pfam04932
O-Antigen ligase; This group of bacterial proteins is involved in the synthesis of O-antigen, ...
188-343 1.06e-05

O-Antigen ligase; This group of bacterial proteins is involved in the synthesis of O-antigen, a lipopolysaccharide found in the outer membrane in gram-negative bacteria. This family includes O-antigen ligases such as E. coli RfaL.


Pssm-ID: 461489  Cd Length: 148  Bit Score: 45.08  E-value: 1.06e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2131487360 188 FTILISYFVILLTGTRAAM-GLYLLLAIVLTLYHFRKIHLKSALIFLCIVAGVVIVSYKPLISPKIQQtqrevERYQQGF 266
Cdd:pfam04932   1 LALVLLLLALVLTGSRGALlALLVALLLLLLLYLRRRLRRRLLALVLLGVLLLFALLFLADGLFTLGR-----LVSALQA 75
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2131487360 267 DRTSLGARFSMWTIGIENGLAHPL-GQSLeereAWTRHYIKDGHPHLGSALEYIKvHLHNEFIEKYSLQGIPGVAVML 343
Cdd:pfam04932  76 KDGSSSGRLEIWKSALDLIKDHPLlGVGA----GTGLAYAAYLLYAQLLGSGGYT-HAHNLYLEILAELGIPGLLLFL 148
 
Name Accession Description Interval E-value
RfaL COG3307
O-antigen ligase [Cell wall/membrane/envelope biogenesis];
154-393 8.88e-21

O-antigen ligase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442536 [Multi-domain]  Cd Length: 239  Bit Score: 90.53  E-value: 8.88e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2131487360 154 NRATVSAYVYSVLSLAFVYSLYLQQNVKLYVVAGFTILISYFVILLTGTRAAMGLYLLLAIVLTLYHFRKIHLKSALIFL 233
Cdd:COG3307     4 NPNHLAAYLALALPLLLALLLLLKRRRLRRLLALLALLLALLALLLTGSRGAWLALLVGLLLLLLLYKRKLRLRRLLLLL 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2131487360 234 CIVAGVVIVSYkPLISPKIQQTQREVERyqqgfDRTSLGARFSMWTIGIENGLAHP-LGQSLEEREAWTRHYIKDGHPHL 312
Cdd:COG3307    84 LAALLLLLLAL-ILVSPPLAERLLEILG-----KDSSLGGRLEIWKAALEMIKEHPlLGVGYGNFWYAYPAYQPAGYIWN 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2131487360 313 GsaleyikVHLHNEFIEKYSLQGIPGVAVMLFFFVSMIVYALRNRNALLLTSMLLLL-----LYGLTDVILLSSEALIFF 387
Cdd:COG3307   158 A-------GHAHNEYLEILAETGILGLLLLLLLLLVLLRRALRRLRRSRLALALLALllallVHGLTESPLFSPASALLF 230

                  ....*.
gi 2131487360 388 MILFAL 393
Cdd:COG3307   231 WLLLAL 236
Wzy_C pfam04932
O-Antigen ligase; This group of bacterial proteins is involved in the synthesis of O-antigen, ...
188-343 1.06e-05

O-Antigen ligase; This group of bacterial proteins is involved in the synthesis of O-antigen, a lipopolysaccharide found in the outer membrane in gram-negative bacteria. This family includes O-antigen ligases such as E. coli RfaL.


Pssm-ID: 461489  Cd Length: 148  Bit Score: 45.08  E-value: 1.06e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2131487360 188 FTILISYFVILLTGTRAAM-GLYLLLAIVLTLYHFRKIHLKSALIFLCIVAGVVIVSYKPLISPKIQQtqrevERYQQGF 266
Cdd:pfam04932   1 LALVLLLLALVLTGSRGALlALLVALLLLLLLYLRRRLRRRLLALVLLGVLLLFALLFLADGLFTLGR-----LVSALQA 75
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2131487360 267 DRTSLGARFSMWTIGIENGLAHPL-GQSLeereAWTRHYIKDGHPHLGSALEYIKvHLHNEFIEKYSLQGIPGVAVML 343
Cdd:pfam04932  76 KDGSSSGRLEIWKSALDLIKDHPLlGVGA----GTGLAYAAYLLYAQLLGSGGYT-HAHNLYLEILAELGIPGLLLFL 148
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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