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Conserved domains on  [gi|2155676973|dbj|GJM23999|]
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MAG: hypothetical protein DHS20C16_04140 [Phycisphaerae bacterium]

Protein Classification

YraN family protein( domain architecture ID 10002721)

YraN family protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YraN COG0792
Predicted endonuclease distantly related to archaeal Holliday junction resolvase, YraN/UPF0102 ...
 14-131 7.05e-47

Predicted endonuclease distantly related to archaeal Holliday junction resolvase, YraN/UPF0102 family [Replication, recombination and repair];


:

Pssm-ID: 440555  Cd Length: 116  Bit Score: 147.20  E-value: 7.05e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155676973  14 RAKPLGDYGERIARRFLKRKGYRIVQSNYTCPIGELDIIAADDDVLVFVEVKTRRSADEGDPEESVNWHKRCKVTKVARY 93
Cdd:COG0792     1 RRRELGRRGEDLAARYLERKGYRILARNWRCRGGEIDLIARDGDTLVFVEVKTRRSARFGGPAEAVTPRKQRRLRRAAEA 80

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 2155676973  94 FIS-HKNAHNMTARFDVVAVLVPQSQkptITHFVDAFGP 131
Cdd:COG0792    81 YLArHPGLADLPVRFDVVAVTGDGRE---IEHIENAFDA 116
 
Name Accession Description Interval E-value
YraN COG0792
Predicted endonuclease distantly related to archaeal Holliday junction resolvase, YraN/UPF0102 ...
 14-131 7.05e-47

Predicted endonuclease distantly related to archaeal Holliday junction resolvase, YraN/UPF0102 family [Replication, recombination and repair];


Pssm-ID: 440555  Cd Length: 116  Bit Score: 147.20  E-value: 7.05e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155676973  14 RAKPLGDYGERIARRFLKRKGYRIVQSNYTCPIGELDIIAADDDVLVFVEVKTRRSADEGDPEESVNWHKRCKVTKVARY 93
Cdd:COG0792     1 RRRELGRRGEDLAARYLERKGYRILARNWRCRGGEIDLIARDGDTLVFVEVKTRRSARFGGPAEAVTPRKQRRLRRAAEA 80

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 2155676973  94 FIS-HKNAHNMTARFDVVAVLVPQSQkptITHFVDAFGP 131
Cdd:COG0792    81 YLArHPGLADLPVRFDVVAVTGDGRE---IEHIENAFDA 116
PRK12497 PRK12497
YraN family protein;
14-130 3.47e-45

YraN family protein;


Pssm-ID: 237119  Cd Length: 119  Bit Score: 143.02  E-value: 3.47e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155676973  14 RAKPLGDYGERIARRFLKRKGYRIVQSNYTCPIGELDIIAADDDVLVFVEVKTRRSADEGDPEESVNWHKRCKVTKVARY 93
Cdd:PRK12497    4 KKRQLGAAGEDLAARYLESKGLRILARNFRCRFGEIDLIARDGDTLVFVEVKTRRSDRFGGAAEAVTPRKQRRLRRAAQL 83

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 2155676973  94 FIS-HKNAHNMTARFDVVAVLVPqsqKPTITHFVDAFG 130
Cdd:PRK12497   84 WLArHPSLADLPCRFDVVAIGGP---GPEIEHIKNAFD 118
UPF0102 pfam02021
Uncharacterized protein family UPF0102; The function of this family is unknown.
 22-112 1.10e-41

Uncharacterized protein family UPF0102; The function of this family is unknown.


Pssm-ID: 460416 [Multi-domain]  Cd Length: 92  Bit Score: 133.29  E-value: 1.10e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155676973  22 GERIARRFLKRKGYRIVQSNYTCPIGELDIIAADDDVLVFVEVKTRRSADEGDPEESVNWHKRCKVTKVARYFIS-HKNA 100
Cdd:pfam02021   1 GEDLAARYLEAKGYRILARNWRCRFGEIDIIARDGDTLVFVEVKTRSSTRFGSPAEAVTPRKQRRLRRAAAAYLAeHPLY 80

                          90
                  ....*....|..
gi 2155676973 101 HNMTARFDVVAV 112
Cdd:pfam02021  81 ADLPCRFDVIAV 92
PoNe_Nuclease cd20736
Polymorphic Nuclease effector (PoNe) co-occurring with an N-terminal nuclease domain; The ...
 18-95 2.52e-25

Polymorphic Nuclease effector (PoNe) co-occurring with an N-terminal nuclease domain; The DNase toxin domain called PoNe (Polymorphic Nuclease effector) belongs to a diverse superfamily of PD-(D/E)xK phosphodiesterases, and is associated with several toxin delivery systems including type V, type VI, and type VII. PoNe toxicity is antagonized by cognate immunity proteins (PoNi) containing DUF1911 and DUF1910 domains. This subfamily contains proteins with PoNe domains that typically co-occur with nuclease N-terminal domains such as endonucleases involved in methyl-directed DNA mismatch repair in gram negative bacteria.


Pssm-ID: 410645 [Multi-domain]  Cd Length: 80  Bit Score: 91.52  E-value: 2.52e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155676973  18 LGDYGERIARRFLKRKGYRIVQSNYTCPIGELDIIAADDDV--LVFVEVKTRRSADEGDPEESVNWHKRCKVTKVARYFI 95
Cdd:cd20736     1 LGAWGEDIAARYLREKGYRILERNYRGGGGEIDLIARDPETgtIVFVEVKTRRSDKFGHPGEAVTRAKQRRLIKAALEYL 80
TIGR00252 TIGR00252
TIGR00252 family protein; the scores for Mycobacterium tuberculosis and Treponema pallidum are ...
 16-112 3.57e-23

TIGR00252 family protein; the scores for Mycobacterium tuberculosis and Treponema pallidum are low considering the alignment [Hypothetical proteins, Conserved]


Pssm-ID: 129354  Cd Length: 119  Bit Score: 87.27  E-value: 3.57e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155676973  16 KPLGDYGERIARRFLKRKGYRIVQSNYTCPIGELDIIAADDDVLVFVEVKTRRSADEGDPEESVNWHKRCKVTKVARYFI 95
Cdd:TIGR00252   6 TQLGQAGESQARAWLEQKGLKFIAANWNSPWGEIDLIMHDTKTIAFVEVRTRSGGNYGGALLSVNARKQEKILQTANLWL 85

                          90
                  ....*....|....*....
gi 2155676973  96 SHKNAHNMTA--RFDVVAV 112
Cdd:TIGR00252  86 ASQNPSWSDWncRFDVMAF 104
 
Name Accession Description Interval E-value
YraN COG0792
Predicted endonuclease distantly related to archaeal Holliday junction resolvase, YraN/UPF0102 ...
 14-131 7.05e-47

Predicted endonuclease distantly related to archaeal Holliday junction resolvase, YraN/UPF0102 family [Replication, recombination and repair];


Pssm-ID: 440555  Cd Length: 116  Bit Score: 147.20  E-value: 7.05e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155676973  14 RAKPLGDYGERIARRFLKRKGYRIVQSNYTCPIGELDIIAADDDVLVFVEVKTRRSADEGDPEESVNWHKRCKVTKVARY 93
Cdd:COG0792     1 RRRELGRRGEDLAARYLERKGYRILARNWRCRGGEIDLIARDGDTLVFVEVKTRRSARFGGPAEAVTPRKQRRLRRAAEA 80

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 2155676973  94 FIS-HKNAHNMTARFDVVAVLVPQSQkptITHFVDAFGP 131
Cdd:COG0792    81 YLArHPGLADLPVRFDVVAVTGDGRE---IEHIENAFDA 116
PRK12497 PRK12497
YraN family protein;
14-130 3.47e-45

YraN family protein;


Pssm-ID: 237119  Cd Length: 119  Bit Score: 143.02  E-value: 3.47e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155676973  14 RAKPLGDYGERIARRFLKRKGYRIVQSNYTCPIGELDIIAADDDVLVFVEVKTRRSADEGDPEESVNWHKRCKVTKVARY 93
Cdd:PRK12497    4 KKRQLGAAGEDLAARYLESKGLRILARNFRCRFGEIDLIARDGDTLVFVEVKTRRSDRFGGAAEAVTPRKQRRLRRAAQL 83

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 2155676973  94 FIS-HKNAHNMTARFDVVAVLVPqsqKPTITHFVDAFG 130
Cdd:PRK12497   84 WLArHPSLADLPCRFDVVAIGGP---GPEIEHIKNAFD 118
UPF0102 pfam02021
Uncharacterized protein family UPF0102; The function of this family is unknown.
 22-112 1.10e-41

Uncharacterized protein family UPF0102; The function of this family is unknown.


Pssm-ID: 460416 [Multi-domain]  Cd Length: 92  Bit Score: 133.29  E-value: 1.10e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155676973  22 GERIARRFLKRKGYRIVQSNYTCPIGELDIIAADDDVLVFVEVKTRRSADEGDPEESVNWHKRCKVTKVARYFIS-HKNA 100
Cdd:pfam02021   1 GEDLAARYLEAKGYRILARNWRCRFGEIDIIARDGDTLVFVEVKTRSSTRFGSPAEAVTPRKQRRLRRAAAAYLAeHPLY 80

                          90
                  ....*....|..
gi 2155676973 101 HNMTARFDVVAV 112
Cdd:pfam02021  81 ADLPCRFDVIAV 92
PRK14675 PRK14675
hypothetical protein; Provisional
 16-129 6.82e-32

hypothetical protein; Provisional


Pssm-ID: 173138  Cd Length: 125  Bit Score: 109.54  E-value: 6.82e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155676973  16 KPLGDYGERIARRFLKRKGYRIVQSNYTCPIGELDIIAADDDVLVFVEVKTRRSADEGDPEESVNWHKRCKVTKVARYFI 95
Cdd:PRK14675    8 KSLGEIGESIAVTYLKGLRYKIVERNFRCRCGEIDIIARDGKTLVFVEVKTRKNYAYGVPQLAVTPFKQRQISKAALTWL 87

                          90       100       110
                  ....*....|....*....|....*....|....
gi 2155676973  96 SHKNAHNMTARFDVVAVLVPQSQKPTITHFVDAF 129
Cdd:PRK14675   88 AKKKLLDAEARFDVIAITQRDHAVPEIEHIKNAF 121
PoNe_Nuclease cd20736
Polymorphic Nuclease effector (PoNe) co-occurring with an N-terminal nuclease domain; The ...
 18-95 2.52e-25

Polymorphic Nuclease effector (PoNe) co-occurring with an N-terminal nuclease domain; The DNase toxin domain called PoNe (Polymorphic Nuclease effector) belongs to a diverse superfamily of PD-(D/E)xK phosphodiesterases, and is associated with several toxin delivery systems including type V, type VI, and type VII. PoNe toxicity is antagonized by cognate immunity proteins (PoNi) containing DUF1911 and DUF1910 domains. This subfamily contains proteins with PoNe domains that typically co-occur with nuclease N-terminal domains such as endonucleases involved in methyl-directed DNA mismatch repair in gram negative bacteria.


Pssm-ID: 410645 [Multi-domain]  Cd Length: 80  Bit Score: 91.52  E-value: 2.52e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155676973  18 LGDYGERIARRFLKRKGYRIVQSNYTCPIGELDIIAADDDV--LVFVEVKTRRSADEGDPEESVNWHKRCKVTKVARYFI 95
Cdd:cd20736     1 LGAWGEDIAARYLREKGYRILERNYRGGGGEIDLIARDPETgtIVFVEVKTRRSDKFGHPGEAVTRAKQRRLIKAALEYL 80
PRK14678 PRK14678
hypothetical protein; Provisional
 14-132 8.83e-24

hypothetical protein; Provisional


Pssm-ID: 173141  Cd Length: 120  Bit Score: 88.78  E-value: 8.83e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155676973  14 RAKPLGDYGERIARRFLKRKGYRIVQSNYTCPIGELDIIAADDDVLVFVEVKTRRSADEGdpeESVNWHKRCKVTKVARY 93
Cdd:PRK14678    4 PKRRLGDWGEQVAAAYLERCGYTIIARNWRCRAGEIDIVAREGDQLVFVEVRTRRDQDAL---ESITLAKRQRLVALAYH 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 2155676973  94 FIShknAHNMTA----RFDVVAVLVPQSQKPTITHFVDAFGPT 132
Cdd:PRK14678   81 YLA---AHDLPAttpwRIDVIALTVRGGRIVDIDHVIAAVGED 120
TIGR00252 TIGR00252
TIGR00252 family protein; the scores for Mycobacterium tuberculosis and Treponema pallidum are ...
 16-112 3.57e-23

TIGR00252 family protein; the scores for Mycobacterium tuberculosis and Treponema pallidum are low considering the alignment [Hypothetical proteins, Conserved]


Pssm-ID: 129354  Cd Length: 119  Bit Score: 87.27  E-value: 3.57e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155676973  16 KPLGDYGERIARRFLKRKGYRIVQSNYTCPIGELDIIAADDDVLVFVEVKTRRSADEGDPEESVNWHKRCKVTKVARYFI 95
Cdd:TIGR00252   6 TQLGQAGESQARAWLEQKGLKFIAANWNSPWGEIDLIMHDTKTIAFVEVRTRSGGNYGGALLSVNARKQEKILQTANLWL 85

                          90
                  ....*....|....*....
gi 2155676973  96 SHKNAHNMTA--RFDVVAV 112
Cdd:TIGR00252  86 ASQNPSWSDWncRFDVMAF 104
PRK14680 PRK14680
hypothetical protein; Provisional
 18-133 9.82e-23

hypothetical protein; Provisional


Pssm-ID: 173143  Cd Length: 134  Bit Score: 86.42  E-value: 9.82e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155676973  18 LGDYGERIARRFLKRKGYRIVQSNYTCPIGELDIIAADDDVLVFVEVKTRRSADEGDPEESVNWHKRCKVTKVARYFISH 97
Cdd:PRK14680    8 IGQHGEDAAAALLQRTGHRILARNWRHGGLELDIVCEDGDTIVFVEVKTRAAHGLTSPTDALTHSKRHRLIRAARAWLAA 87

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 2155676973  98 KNAHNMTARFDVVAVLvpqSQKPTIT--HFVDAFGPTP 133
Cdd:PRK14680   88 HDAWDKPCRFDLVCVT---QRGATLTleHYTHAFDLTE 122
PRK14686 PRK14686
hypothetical protein; Provisional
 18-129 3.06e-22

hypothetical protein; Provisional


Pssm-ID: 184791  Cd Length: 119  Bit Score: 84.81  E-value: 3.06e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155676973  18 LGDYGERIARRFLKRKGYRIVQSNYTCPIGELDIIAADDDVLVFVEVKTRRSADEGDPEESVNWHKRCKVTKVARYFISh 97
Cdd:PRK14686    7 LGKEGEDLAVEFLIKKGYTILERNYRFQKAEIDIIAQKGNILVIVEVKTRSSSDFGNPQDFVKPKKIQLLVKAVNHYIE- 85

                          90       100       110
                  ....*....|....*....|....*....|..
gi 2155676973  98 KNAHNMTARFDVVAVlVPQSQKPTITHFVDAF 129
Cdd:PRK14686   86 DKDLDVEIRFDIIAI-VKNKAGFKIEHIEDAF 116
PRK14673 PRK14673
hypothetical protein; Provisional
 15-112 3.73e-21

hypothetical protein; Provisional


Pssm-ID: 237786  Cd Length: 137  Bit Score: 82.42  E-value: 3.73e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155676973  15 AKPLGDYGERIARRFLKRKGYRIVQSNYTCPIGELDIIAAD-DDVLVFVEVKTRRSADEGDPEESVNWHKRCKVTKVARY 93
Cdd:PRK14673   25 TRAVGAAFEDRALAFLQRAGLALVARNYRCRGGEIDLVMRErDGTLVFVEVRARASRRFGGAAASIGARKQRRLVAAALH 104

                          90
                  ....*....|....*....
gi 2155676973  94 FISHKNAHNmTARFDVVAV 112
Cdd:PRK14673  105 FLARHGGAP-ACRFDVVAF 122
PRK14688 PRK14688
hypothetical protein; Provisional
 11-130 5.68e-21

hypothetical protein; Provisional


Pssm-ID: 184792  Cd Length: 121  Bit Score: 81.63  E-value: 5.68e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155676973  11 LSWRAKPLGDYGERIARRFLKRKGYRIVQSNYTCPIGELDIIAADDDVLVFVEVKTRRSADEGDPEESVNWHKRCKVTKV 90
Cdd:PRK14688    1 MAYNRKETGEFGEKLAAEYLKGMGYSIIQTNCRLPEGEIDIVGQDGEYLVFIEVRTKRRLGYGLPAESVTPRKKAHLMAS 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 2155676973  91 ARYFISHKNAHNMTARFDVVAVLVPQSQkPTITHFVDAFG 130
Cdd:PRK14688   81 AESYIQKHRLEHFPCRIDFVSVDLSQPE-PRLELIKNALG 119
PRK14681 PRK14681
hypothetical protein; Provisional
 14-129 9.04e-21

hypothetical protein; Provisional


Pssm-ID: 237787  Cd Length: 158  Bit Score: 82.28  E-value: 9.04e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155676973  14 RAKPLGDYGERIARRFLKRKGYRIVQSNYTCPIGELDIIAADDD-VLVFVEVKTRRSADEGDPEESVNWHKRCKVTKVA- 91
Cdd:PRK14681   41 TPKQIGALGEQYAAAWLEEHGWTTLSRNWHCRYGELDIVALNPEyTIVFVEVKTRRSMHYGYPQEAVTAAKQHNLRKAAc 120

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 2155676973  92 RYFISHKN-AHNMTARFDVVAVLVpQSQKPTITHFVDAF 129
Cdd:PRK14681  121 DWLLERRNrVPHIGVRFDVVTVVV-RVGRPLVHHIENAF 158
PRK14674 PRK14674
hypothetical protein; Provisional
 15-124 4.79e-19

hypothetical protein; Provisional


Pssm-ID: 184788  Cd Length: 133  Bit Score: 76.93  E-value: 4.79e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155676973  15 AKPLGDYGERIARRFLKRKGYRIVQSNYTCPIGELDIIAADDDVLVFVEVKTRRSADEGDPEESVNWHKRCKVTKVARYF 94
Cdd:PRK14674    4 AQQLGQWAEQTALKLLKEQNYEWVASNYHSRRGEVDLIVKRGNELIFVEVKARGQGNYGQACEMVTLSKQKKIIKTAMRF 83

                          90       100       110
                  ....*....|....*....|....*....|.
gi 2155676973  95 IS-HKNAHNMTARFDVVAVLVPQSQKPTITH 124
Cdd:PRK14674   84 LQrYPSYQDFYCRFDVICFDFPQKIAKTVQQ 114
PRK14687 PRK14687
hypothetical protein; Provisional
 4-111 9.70e-17

hypothetical protein; Provisional


Pssm-ID: 237788  Cd Length: 173  Bit Score: 71.97  E-value: 9.70e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155676973   4 LLKRLPFLSWRAKPL---------GDYGERIARRFLKRKGYRIVQSNYTCP-IGELDIIAADD----DVLVFVEVKTRRS 69
Cdd:PRK14687    9 MLSRLIDVMANDKPLmltspkqrqGGGFEQLACEFLQEQGLILIARNWQQPkVGELDLVMLEKgqawSTLVFAEVRQRKL 88

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 2155676973  70 ADEGDPEESVNWHKRCKVTKVARYFI-SHKNAHNMTARFDVVA 111
Cdd:PRK14687   89 SGFGDAAASVTAGKQRKIIKTARYFLrQHPEYADYECRFDVIA 131
PRK14682 PRK14682
hypothetical protein; Provisional
 18-130 1.50e-15

hypothetical protein; Provisional


Pssm-ID: 173145  Cd Length: 117  Bit Score: 67.77  E-value: 1.50e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155676973  18 LGDYGERIARRFLKRKGYRIVQSNYTC-PIGELDIIAADDDVLVFVEVKTRRSADEGDPEESVNWHKRCKVTKVARYFIS 96
Cdd:PRK14682    6 IGNKAELQACKFLHTQALEILAHNFKAlPYGEIDIIALDKDTLVFIEVKYRSKTKFAQAEEMLTYSKQQKLVNSASIYLQ 85

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 2155676973  97 HK-NAHNMTARFDVVAVlvpqsQKPTITHFVDAFG 130
Cdd:PRK14682   86 HNpQYQDYQCRFDLIAI-----NESNINWIKNAFG 115
PRK14683 PRK14683
hypothetical protein; Provisional
 18-109 1.41e-14

hypothetical protein; Provisional


Pssm-ID: 173146  Cd Length: 122  Bit Score: 65.29  E-value: 1.41e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155676973  18 LGDYGERIARRFLKRKGYRIVQSNYTCPIGELDIIAADDDVLVFVEVKTR--RSadegdpEESVNWHKRCKVTKVARYFI 95
Cdd:PRK14683   15 LGYLGEVLIILFLKCKLYHIIKHRYRCPLGEIDIIAHKNKQLVFIEVKTSlfNK------NIPITYKQQKSILKSAKYFI 88

                          90
                  ....*....|....*
gi 2155676973  96 S-HKNAHNMTARFDV 109
Cdd:PRK14683   89 AfHRKFANYSIRFDL 103
PRK14689 PRK14689
hypothetical protein; Provisional
 17-115 3.58e-12

hypothetical protein; Provisional


Pssm-ID: 173152  Cd Length: 124  Bit Score: 58.97  E-value: 3.58e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155676973  17 PLGDYGERIARRFLKRKGYRIVQSNYTCPIGELDIIAADDDVLVFVEVKTRRSA--DEGDPeESVNWHKRCKVTKVARYF 94
Cdd:PRK14689    9 ALGAWAEERVLRLLQRRGWRLLDRNWSCRWGELDLVLEKQQRLLVVEVKGRRRRglDGWGL-AAFHPRKRRRLARAINCW 87

                          90       100
                  ....*....|....*....|.
gi 2155676973  95 ISHkNAHNMTARFDVVAVLVP 115
Cdd:PRK14689   88 RAA-HPYSAEHLLEVVLALVP 107
PRK14677 PRK14677
hypothetical protein; Provisional
 11-112 5.42e-12

hypothetical protein; Provisional


Pssm-ID: 184789  Cd Length: 107  Bit Score: 57.99  E-value: 5.42e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155676973  11 LSWRAkplgdyGERIARRFLKRKGYRIVQSNYTCPIGELDIIAADDDVLVFVEVKTRRSadEGDPEESVNWHKRCKVTKV 90
Cdd:PRK14677    1 MDWKE------AEELACKFLKKKGYKILERNYRTKYGEIDIVARDGREIVFVEVKSGSG--KVDPLERIDLKKVRNLEQT 72

                          90       100
                  ....*....|....*....|..
gi 2155676973  91 ARYFISHKNAHNmTARFDVVAV 112
Cdd:PRK14677   73 ARFYMIQNKLKG-PARVDFVRV 93
PRK14684 PRK14684
hypothetical protein; Provisional
 16-112 5.75e-11

hypothetical protein; Provisional


Pssm-ID: 173147  Cd Length: 120  Bit Score: 55.81  E-value: 5.75e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155676973  16 KPLGDYGERIARRFLKRKGYRIVQSNYTCPIGELDIIAADDDVLVFVEVKTRRSADEGDPEESVNWHKRCKVTKVARYFI 95
Cdd:PRK14684    6 QKIGFNAEKTACRYLQKQGLSFITKNFRYKQGEIDLIMSDQSMLVFIEVRYRRFSDFIHPVATVTPLKQRRLIKTALHYL 85

                          90
                  ....*....|....*...
gi 2155676973  96 S-HKNAHNMTARFDVVAV 112
Cdd:PRK14684   86 QkHRLLDKISCRFDIVGI 103
PRK14685 PRK14685
hypothetical protein; Provisional
 5-111 3.05e-08

hypothetical protein; Provisional


Pssm-ID: 173148  Cd Length: 177  Bit Score: 49.78  E-value: 3.05e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155676973   5 LKRLPFLSWRAKP-----------LGDYGERIARRFLKRKGYRIVQSNYTCPIGELDIIAADDDVLVFVEVKTRRSADEG 73
Cdd:PRK14685   20 LHRRPPASPRARPgardggsptqrCGQAYESAALRWLARQGLRPLARNLRCRAGEIDLAMRDGEVLVLVEVRARAHAGYG 99

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 2155676973  74 DPEESVNWHKRCKVTKVARYFI-----SHKNAHNMTARFDVVA 111
Cdd:PRK14685  100 GAAASIGASKQGRLARAAALLLpvllrRHWPGAPPPVRFDVVA 142
PoNe cd20702
Polymorphic Nuclease effector (PoNe) domain is a deoxyribonuclease; This family contains the ...
 18-69 9.60e-07

Polymorphic Nuclease effector (PoNe) domain is a deoxyribonuclease; This family contains the DNase toxin domain called PoNe (Polymorphic Nuclease effector), which belongs to a diverse superfamily of PD-(D/E)xK phosphodiesterases, and is associated with several toxin delivery systems including type V, type VI, and type VII. PoNe toxicity is antagonized by cognate immunity proteins (PoNi) containing DUF1911 and DUF1910 domains. The PoNe domain co-occurs with a variety of N-terminal domains such as filamentous hemagglutinin, nuclease, HINT, DUFs, PAAR, RHS repeat, or LXG domains. Some members of this family also co-occur with the FIX (Found in type sIX effector) domain of unknown function, as identified by Jana et al., who have also identified this PoNe domain.


Pssm-ID: 410637  Cd Length: 77  Bit Score: 43.51  E-value: 9.60e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2155676973  18 LGDYGERIARRFLKRKGYRIVQSNYTCPIGE-LDIIAADDDV--LVFVEVKTRRS 69
Cdd:cd20702     1 KGELGELAADLYLKSQGYTKLIGGSKGGGGNgIDGVYKDPKGpeYIIVEAKFGSA 55
PRK14679 PRK14679
hypothetical protein; Provisional
 19-129 1.88e-06

hypothetical protein; Provisional


Pssm-ID: 173142  Cd Length: 128  Bit Score: 44.12  E-value: 1.88e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155676973  19 GDYGERIARRFLKRKGYRIVQSNYTCPIGELDIIAADDDVLVFVEVKTRRSADegDPEESVNWHKRCKVTKVARYFIS-H 97
Cdd:PRK14679   18 GLSAEGLALLALMLKGYRPLARRFAAAGGEIDLIVRRGRTIAFVEVKARATLD--AAATAIDARKRARFSRAARAWLArH 95

                          90       100       110
                  ....*....|....*....|....*....|..
gi 2155676973  98 KNAHNMTARFDvvAVLVPQSQKPtiTHFVDAF 129
Cdd:PRK14679   96 PLAAGATLRAD--AVFVAPRRWP--RHLPNAF 123
PRK14676 PRK14676
hypothetical protein; Provisional
 19-112 3.72e-06

hypothetical protein; Provisional


Pssm-ID: 173139  Cd Length: 117  Bit Score: 43.01  E-value: 3.72e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2155676973  19 GDYGERIARRFLKRKGYRIVQSNYTCPIGELDIIAADDDVLVFVEVKtrRSADEGDPEESVNWHKRCKVTKVARYFISHK 98
Cdd:PRK14676   10 GQTAEEAVARIYDRSGRPVAARRWRGVSGEIDLIAREGAEVIFIEVK--KSKSHAAAAARLSRRQMDRIYGAASEFLAGE 87

                          90
                  ....*....|....*
gi 2155676973  99 NAHNMTA-RFDVVAV 112
Cdd:PRK14676   88 PRGQLTAsRFDVALV 102
NERD pfam08378
Nuclease-related domain; The nuclease-related domain (NERD) is found in a range of bacterial ...
 19-86 1.71e-04

Nuclease-related domain; The nuclease-related domain (NERD) is found in a range of bacterial as well as archaeal and plant proteins. It has distant similarity to endonucleases (hence its name) and its predicted secondary structure is helix - sheet - sheet - sheet - sheet - weak sheet/long loop - helix - sheet - sheet. The majority of NERD-containing proteins are single-domain, but in several cases proteins containing NERD have additional domains which in 75% of cases are involved in DNA processing.


Pssm-ID: 462454  Cd Length: 108  Bit Score: 38.20  E-value: 1.71e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2155676973  19 GDYGERIARRFLKRKGYRIVQSNYTCP----IGELDIIAADDDVLVFVEVKTRRSADEGDPEEsvNWHKRCK 86
Cdd:pfam08378   2 GAKGERRVAEYLKLPGGYIVLHNLRLPpgtgTAEIDHLVISPNGIFVIEVKNYSGWIFGDENG--QWTQKIG 71
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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