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Conserved domains on  [gi|958193332|gb|JAO13997|]
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SEZ6 [Poeciliopsis prolifica]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 441-551 1.02e-24

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


:

Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 99.41  E-value: 1.02e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 958193332 441 CGGMIKNATYGRIVSPGFPGNYSNNLTCHWVLEAPEGHRLHIHFEKVALAEDD----DRLLIKNGNNiDSPPVYDSYEVE 516
Cdd:cd00041    1 CGGTLTASTSGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSPncsyDYLEIYDGPS-TSSPLLGRFCGS 79

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 958193332 517 YLPNEgVLSTGRYLFVEFTTDGTMTSTGAAIRYEA 551
Cdd:cd00041   80 TLPPP-IISSGNSLTVRFRSDSSVTGRGFKATYSA 113
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 618-727 2.04e-22

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


:

Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 92.86  E-value: 2.04e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 958193332 618 CSGEITDSA-GVVLSPNWPEAYDKGQDCIWGIHVEEDKRIMLDIQVLNLG-----KNDQLTFYDGDDLTGNILGQYSGAR 691
Cdd:cd00041    1 CGGTLTASTsGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLEsspncSYDYLEIYDGPSTSSPLLGRFCGST 80

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 958193332 692 PHFKLYTSMADVTIQFQSDPATNiygyNNGFVVHFF 727
Cdd:cd00041   81 LPPPIISSGNSLTVRFRSDSSVT----GRGFKATYS 112
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 735-790 1.30e-15

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


:

Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 71.40  E-value: 1.30e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 958193332   735 CPELPEIPNGWKSTSHPDLIHGTVVTYQCYPGFALVGSEILMCQWDLTWSGDVPKC 790
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
557-614 1.23e-10

Sushi repeat (SCR repeat);


:

Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 57.51  E-value: 1.23e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 958193332  557 CYEPF-VKYGNFSSSDSTYSMGAVVEFSCNPGYTLeQGSVVIECvdSQNPQWNETEPAC 614
Cdd:pfam00084   1 CPPPPdIPNGKVSATKNEYNYGASVSYECDPGYRL-VGSPTITC--QEDGTWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 382-438 2.46e-07

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


:

Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 48.23  E-value: 2.46e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 958193332 382 CTFPKEPAGGEV--SVTNLHAGGEAYFSCFTGYKLQGPKMLTCRNATTpyWSGKEPQCI 438
Cdd:cd00033    1 CPPPPVPENGTVtgSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGG--WSPPPPTCE 57
CUB super family cl00049
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 274-377 7.77e-03

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


The actual alignment was detected with superfamily member cd00041:

Pssm-ID: 412131 [Multi-domain]  Cd Length: 113  Bit Score: 37.01  E-value: 7.77e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 958193332 274 CSMNFTES-EGNIA---IQQHVDPGVECTYLITVYLGYGIEVQVLNVSVMEGEQ-----ITVEDTGGQEPFILANESVLM 344
Cdd:cd00041    1 CGGTLTAStSGTISspnYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSPNcsydyLEIYDGPSTSSPLLGRFCGST 80

                         90       100       110
                 ....*....|....*....|....*....|....
gi 958193332 345 RGLVLRSWSNQISIRFRGNQRLN-SGFlLLHYQA 377
Cdd:cd00041   81 LPPPIISSGNSLTVRFRSDSSVTgRGF-KATYSA 113
 
Name Accession Description Interval E-value
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 441-551 1.02e-24

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 99.41  E-value: 1.02e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 958193332 441 CGGMIKNATYGRIVSPGFPGNYSNNLTCHWVLEAPEGHRLHIHFEKVALAEDD----DRLLIKNGNNiDSPPVYDSYEVE 516
Cdd:cd00041    1 CGGTLTASTSGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSPncsyDYLEIYDGPS-TSSPLLGRFCGS 79

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 958193332 517 YLPNEgVLSTGRYLFVEFTTDGTMTSTGAAIRYEA 551
Cdd:cd00041   80 TLPPP-IISSGNSLTVRFRSDSSVTGRGFKATYSA 113
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 618-727 2.04e-22

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 92.86  E-value: 2.04e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 958193332 618 CSGEITDSA-GVVLSPNWPEAYDKGQDCIWGIHVEEDKRIMLDIQVLNLG-----KNDQLTFYDGDDLTGNILGQYSGAR 691
Cdd:cd00041    1 CGGTLTASTsGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLEsspncSYDYLEIYDGPSTSSPLLGRFCGST 80

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 958193332 692 PHFKLYTSMADVTIQFQSDPATNiygyNNGFVVHFF 727
Cdd:cd00041   81 LPPPIISSGNSLTVRFRSDSSVT----GRGFKATYS 112
CUB smart00042
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ...
 451-549 5.99e-20

Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.


Pssm-ID: 214483 [Multi-domain]  Cd Length: 102  Bit Score: 85.52  E-value: 5.99e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 958193332   451 GRIVSPGFPGNYSNNLTCHWVLEAPEGHRLHIHFEKVALAEDD----DRLLIKNGNNIDSpPVYDSYEVEYLPNEGVLST 526
Cdd:smart00042   1 GTITSPNYPQSYPNNLDCVWTIRAPPGYRIELQFTDFDLESSDnceyDYVEIYDGPSASS-PLLGRFCGSEAPPPVISSS 79

                           90       100
                   ....*....|....*....|...
gi 958193332   527 GRYLFVEFTTDGTMTSTGAAIRY 549
Cdd:smart00042  80 SNSLTLTFVSDSSVQKRGFSARY 102
CUB smart00042
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ...
 627-726 4.86e-18

Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.


Pssm-ID: 214483 [Multi-domain]  Cd Length: 102  Bit Score: 80.13  E-value: 4.86e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 958193332   627 GVVLSPNWPEAYDKGQDCIWGIHVEEDKRIMLDIQVLNLGKN-----DQLTFYDGDDLTGNILGQYSGARPHFKLYTSMA 701
Cdd:smart00042   1 GTITSPNYPQSYPNNLDCVWTIRAPPGYRIELQFTDFDLESSdnceyDYVEIYDGPSASSPLLGRFCGSEAPPPVISSSS 80

                           90       100
                   ....*....|....*....|....*.
gi 958193332   702 D-VTIQFQSDPATNiygyNNGFVVHF 726
Cdd:smart00042  81 NsLTLTFVSDSSVQ----KRGFSARY 102
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 735-790 1.30e-15

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 71.40  E-value: 1.30e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 958193332   735 CPELPEIPNGWKSTSHPDLIHGTVVTYQCYPGFALVGSEILMCQWDLTWSGDVPKC 790
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
CUB pfam00431
CUB domain;
441-549 1.99e-15

CUB domain;


Pssm-ID: 395345 [Multi-domain]  Cd Length: 110  Bit Score: 72.71  E-value: 1.99e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 958193332  441 CGGMIKNATyGRIVSPGFPGNYSNNLTCHWVLEAPEGHRLHIHFEKVALAEDD----DRLLIKNGNNiDSPPVYDSYEVE 516
Cdd:pfam00431   1 CGGVLTDSS-GSISSPNYPNPYPPNKDCVWLIRAPPGFRVKLTFQDFELEDHDecgyDYVEIRDGPS-ASSPLLGRFCGS 78

                          90       100       110
                  ....*....|....*....|....*....|...
gi 958193332  517 YLPnEGVLSTGRYLFVEFTTDGTMTSTGAAIRY 549
Cdd:pfam00431  79 GIP-EDIVSSSNQMTIKFVSDASVQKRGFKATY 110
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 735-790 3.50e-15

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 70.18  E-value: 3.50e-15
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 958193332 735 CPELPEIPNGWKSTSHPDLIHGTVVTYQCYPGFALVGSEILMCQWDLTWSGDVPKC 790
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTC 56
CUB pfam00431
CUB domain;
618-726 5.52e-15

CUB domain;


Pssm-ID: 395345 [Multi-domain]  Cd Length: 110  Bit Score: 71.56  E-value: 5.52e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 958193332  618 CSGEITDSAGVVLSPNWPEAYDKGQDCIWGIHVEEDKRIMLDIQVLNL-----GKNDQLTFYDGDDLTGNILGQYSGARP 692
Cdd:pfam00431   1 CGGVLTDSSGSISSPNYPNPYPPNKDCVWLIRAPPGFRVKLTFQDFELedhdeCGYDYVEIRDGPSASSPLLGRFCGSGI 80

                          90       100       110
                  ....*....|....*....|....*....|....
gi 958193332  693 HFKLYTSMADVTIQFQSDPAtniyGYNNGFVVHF 726
Cdd:pfam00431  81 PEDIVSSSNQMTIKFVSDAS----VQKRGFKATY 110
Sushi pfam00084
Sushi repeat (SCR repeat);
735-790 1.20e-12

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 63.29  E-value: 1.20e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 958193332  735 CPELPEIPNGWKSTSHPDLIHGTVVTYQCYPGFALVGSEILMCQWDLTWSGDVPKC 790
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
557-614 1.23e-10

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 57.51  E-value: 1.23e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 958193332  557 CYEPF-VKYGNFSSSDSTYSMGAVVEFSCNPGYTLeQGSVVIECvdSQNPQWNETEPAC 614
Cdd:pfam00084   1 CPPPPdIPNGKVSATKNEYNYGASVSYECDPGYRL-VGSPTITC--QEDGTWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 560-615 5.71e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 52.85  E-value: 5.71e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 958193332 560 PFVKYGNFSSSDSTYSMGAVVEFSCNPGYTLeQGSVVIECVDsqNPQWNETEPACR 615
Cdd:cd00033    5 PVPENGTVTGSKGSYSYGSTVTYSCNEGYTL-VGSSTITCTE--NGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 560-614 4.82e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 50.22  E-value: 4.82e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 958193332   560 PFVKYGNFSSSDSTYSMGAVVEFSCNPGYTLeQGSVVIECVDsqNPQWNETEPAC 614
Cdd:smart00032   5 PDIENGTVTSSSGTYSYGDTVTYSCDPGYTL-IGSSTITCLE--NGTWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 382-438 2.46e-07

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 48.23  E-value: 2.46e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 958193332 382 CTFPKEPAGGEV--SVTNLHAGGEAYFSCFTGYKLQGPKMLTCRNATTpyWSGKEPQCI 438
Cdd:cd00033    1 CPPPPVPENGTVtgSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGG--WSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 382-437 3.46e-07

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 47.52  E-value: 3.46e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 958193332   382 CTFPKEPAGGEVSVTN--LHAGGEAYFSCFTGYKLQGPKMLTCRNATTpyWSGKEPQC 437
Cdd:smart00032   1 CPPPPDIENGTVTSSSgtYSYGDTVTYSCDPGYTLIGSSTITCLENGT--WSPPPPTC 56
PHA02831 PHA02831
EEV host range protein; Provisional
 729-790 3.03e-04

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 43.44  E-value: 3.03e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 958193332 729 VPRNDTCP----ELPEIPNGWKSTSHPDLIHGTVVTYQCYPGFALVGSEILMCQWDLTWSGDVPKC 790
Cdd:PHA02831 130 VPKYPVCKlircKYPALQNGFLNVFEKKFYYGDIVNFKCKKGFILLGSSVSTCDINSIWYPGIPKC 195
Sushi pfam00084
Sushi repeat (SCR repeat);
382-437 6.53e-04

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 38.25  E-value: 6.53e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 958193332  382 CTFPKEPAGGEVSVT--NLHAGGEAYFSCFTGYKLQGPKMLTCRnaTTPYWSGKEPQC 437
Cdd:pfam00084   1 CPPPPDIPNGKVSATknEYNYGASVSYECDPGYRLVGSPTITCQ--EDGTWSPPFPEC 56
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 274-377 7.77e-03

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 37.01  E-value: 7.77e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 958193332 274 CSMNFTES-EGNIA---IQQHVDPGVECTYLITVYLGYGIEVQVLNVSVMEGEQ-----ITVEDTGGQEPFILANESVLM 344
Cdd:cd00041    1 CGGTLTAStSGTISspnYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSPNcsydyLEIYDGPSTSSPLLGRFCGST 80

                         90       100       110
                 ....*....|....*....|....*....|....
gi 958193332 345 RGLVLRSWSNQISIRFRGNQRLN-SGFlLLHYQA 377
Cdd:cd00041   81 LPPPIISSGNSLTVRFRSDSSVTgRGF-KATYSA 113
 
Name Accession Description Interval E-value
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 441-551 1.02e-24

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 99.41  E-value: 1.02e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 958193332 441 CGGMIKNATYGRIVSPGFPGNYSNNLTCHWVLEAPEGHRLHIHFEKVALAEDD----DRLLIKNGNNiDSPPVYDSYEVE 516
Cdd:cd00041    1 CGGTLTASTSGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSPncsyDYLEIYDGPS-TSSPLLGRFCGS 79

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 958193332 517 YLPNEgVLSTGRYLFVEFTTDGTMTSTGAAIRYEA 551
Cdd:cd00041   80 TLPPP-IISSGNSLTVRFRSDSSVTGRGFKATYSA 113
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 618-727 2.04e-22

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 92.86  E-value: 2.04e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 958193332 618 CSGEITDSA-GVVLSPNWPEAYDKGQDCIWGIHVEEDKRIMLDIQVLNLG-----KNDQLTFYDGDDLTGNILGQYSGAR 691
Cdd:cd00041    1 CGGTLTASTsGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLEsspncSYDYLEIYDGPSTSSPLLGRFCGST 80

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 958193332 692 PHFKLYTSMADVTIQFQSDPATNiygyNNGFVVHFF 727
Cdd:cd00041   81 LPPPIISSGNSLTVRFRSDSSVT----GRGFKATYS 112
CUB smart00042
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ...
 451-549 5.99e-20

Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.


Pssm-ID: 214483 [Multi-domain]  Cd Length: 102  Bit Score: 85.52  E-value: 5.99e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 958193332   451 GRIVSPGFPGNYSNNLTCHWVLEAPEGHRLHIHFEKVALAEDD----DRLLIKNGNNIDSpPVYDSYEVEYLPNEGVLST 526
Cdd:smart00042   1 GTITSPNYPQSYPNNLDCVWTIRAPPGYRIELQFTDFDLESSDnceyDYVEIYDGPSASS-PLLGRFCGSEAPPPVISSS 79

                           90       100
                   ....*....|....*....|...
gi 958193332   527 GRYLFVEFTTDGTMTSTGAAIRY 549
Cdd:smart00042  80 SNSLTLTFVSDSSVQKRGFSARY 102
CUB smart00042
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ...
 627-726 4.86e-18

Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.


Pssm-ID: 214483 [Multi-domain]  Cd Length: 102  Bit Score: 80.13  E-value: 4.86e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 958193332   627 GVVLSPNWPEAYDKGQDCIWGIHVEEDKRIMLDIQVLNLGKN-----DQLTFYDGDDLTGNILGQYSGARPHFKLYTSMA 701
Cdd:smart00042   1 GTITSPNYPQSYPNNLDCVWTIRAPPGYRIELQFTDFDLESSdnceyDYVEIYDGPSASSPLLGRFCGSEAPPPVISSSS 80

                           90       100
                   ....*....|....*....|....*.
gi 958193332   702 D-VTIQFQSDPATNiygyNNGFVVHF 726
Cdd:smart00042  81 NsLTLTFVSDSSVQ----KRGFSARY 102
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 735-790 1.30e-15

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 71.40  E-value: 1.30e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 958193332   735 CPELPEIPNGWKSTSHPDLIHGTVVTYQCYPGFALVGSEILMCQWDLTWSGDVPKC 790
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
CUB pfam00431
CUB domain;
441-549 1.99e-15

CUB domain;


Pssm-ID: 395345 [Multi-domain]  Cd Length: 110  Bit Score: 72.71  E-value: 1.99e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 958193332  441 CGGMIKNATyGRIVSPGFPGNYSNNLTCHWVLEAPEGHRLHIHFEKVALAEDD----DRLLIKNGNNiDSPPVYDSYEVE 516
Cdd:pfam00431   1 CGGVLTDSS-GSISSPNYPNPYPPNKDCVWLIRAPPGFRVKLTFQDFELEDHDecgyDYVEIRDGPS-ASSPLLGRFCGS 78

                          90       100       110
                  ....*....|....*....|....*....|...
gi 958193332  517 YLPnEGVLSTGRYLFVEFTTDGTMTSTGAAIRY 549
Cdd:pfam00431  79 GIP-EDIVSSSNQMTIKFVSDASVQKRGFKATY 110
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 735-790 3.50e-15

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 70.18  E-value: 3.50e-15
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 958193332 735 CPELPEIPNGWKSTSHPDLIHGTVVTYQCYPGFALVGSEILMCQWDLTWSGDVPKC 790
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTC 56
CUB pfam00431
CUB domain;
618-726 5.52e-15

CUB domain;


Pssm-ID: 395345 [Multi-domain]  Cd Length: 110  Bit Score: 71.56  E-value: 5.52e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 958193332  618 CSGEITDSAGVVLSPNWPEAYDKGQDCIWGIHVEEDKRIMLDIQVLNL-----GKNDQLTFYDGDDLTGNILGQYSGARP 692
Cdd:pfam00431   1 CGGVLTDSSGSISSPNYPNPYPPNKDCVWLIRAPPGFRVKLTFQDFELedhdeCGYDYVEIRDGPSASSPLLGRFCGSGI 80

                          90       100       110
                  ....*....|....*....|....*....|....
gi 958193332  693 HFKLYTSMADVTIQFQSDPAtniyGYNNGFVVHF 726
Cdd:pfam00431  81 PEDIVSSSNQMTIKFVSDAS----VQKRGFKATY 110
Sushi pfam00084
Sushi repeat (SCR repeat);
735-790 1.20e-12

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 63.29  E-value: 1.20e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 958193332  735 CPELPEIPNGWKSTSHPDLIHGTVVTYQCYPGFALVGSEILMCQWDLTWSGDVPKC 790
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
557-614 1.23e-10

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 57.51  E-value: 1.23e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 958193332  557 CYEPF-VKYGNFSSSDSTYSMGAVVEFSCNPGYTLeQGSVVIECvdSQNPQWNETEPAC 614
Cdd:pfam00084   1 CPPPPdIPNGKVSATKNEYNYGASVSYECDPGYRL-VGSPTITC--QEDGTWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 560-615 5.71e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 52.85  E-value: 5.71e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 958193332 560 PFVKYGNFSSSDSTYSMGAVVEFSCNPGYTLeQGSVVIECVDsqNPQWNETEPACR 615
Cdd:cd00033    5 PVPENGTVTGSKGSYSYGSTVTYSCNEGYTL-VGSSTITCTE--NGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 560-614 4.82e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 50.22  E-value: 4.82e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 958193332   560 PFVKYGNFSSSDSTYSMGAVVEFSCNPGYTLeQGSVVIECVDsqNPQWNETEPAC 614
Cdd:smart00032   5 PDIENGTVTSSSGTYSYGDTVTYSCDPGYTL-IGSSTITCLE--NGTWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 382-438 2.46e-07

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 48.23  E-value: 2.46e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 958193332 382 CTFPKEPAGGEV--SVTNLHAGGEAYFSCFTGYKLQGPKMLTCRNATTpyWSGKEPQCI 438
Cdd:cd00033    1 CPPPPVPENGTVtgSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGG--WSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 382-437 3.46e-07

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 47.52  E-value: 3.46e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 958193332   382 CTFPKEPAGGEVSVTN--LHAGGEAYFSCFTGYKLQGPKMLTCRNATTpyWSGKEPQC 437
Cdd:smart00032   1 CPPPPDIENGTVTSSSgtYSYGDTVTYSCDPGYTLIGSSTITCLENGT--WSPPPPTC 56
PHA02831 PHA02831
EEV host range protein; Provisional
 729-790 3.03e-04

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 43.44  E-value: 3.03e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 958193332 729 VPRNDTCP----ELPEIPNGWKSTSHPDLIHGTVVTYQCYPGFALVGSEILMCQWDLTWSGDVPKC 790
Cdd:PHA02831 130 VPKYPVCKlircKYPALQNGFLNVFEKKFYYGDIVNFKCKKGFILLGSSVSTCDINSIWYPGIPKC 195
Sushi pfam00084
Sushi repeat (SCR repeat);
382-437 6.53e-04

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 38.25  E-value: 6.53e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 958193332  382 CTFPKEPAGGEVSVT--NLHAGGEAYFSCFTGYKLQGPKMLTCRnaTTPYWSGKEPQC 437
Cdd:pfam00084   1 CPPPPDIPNGKVSATknEYNYGASVSYECDPGYRLVGSPTITCQ--EDGTWSPPFPEC 56
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 735-790 6.72e-03

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 39.25  E-value: 6.72e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 958193332 735 CPELPEIPNGWKSTSHPDLIHGTVVTYQCYPGFALVGSEILMCQWDlTWSgDVPKC 790
Cdd:PHA02927 148 CQSPPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLIGNSGVLCSGG-EWS-DPPTC 201
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 274-377 7.77e-03

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 37.01  E-value: 7.77e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 958193332 274 CSMNFTES-EGNIA---IQQHVDPGVECTYLITVYLGYGIEVQVLNVSVMEGEQ-----ITVEDTGGQEPFILANESVLM 344
Cdd:cd00041    1 CGGTLTAStSGTISspnYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSPNcsydyLEIYDGPSTSSPLLGRFCGST 80

                         90       100       110
                 ....*....|....*....|....*....|....
gi 958193332 345 RGLVLRSWSNQISIRFRGNQRLN-SGFlLLHYQA 377
Cdd:cd00041   81 LPPPIISSGNSLTVRFRSDSSVTgRGF-KATYSA 113
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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